Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

FGD2 SBF2 ARHGEF18 SPRED1 CNKSR2 NIBAN3

1.31e-033915862.30.29.30
DomainPH

FGD2 SBF2 ARHGEF18 CNKSR2 NIBAN3

1.70e-03278585SM00233
DomainHis_PPase_superfam

PPIP5K1 PFKFB2

1.74e-0320582IPR029033
Domain-

PPIP5K1 PFKFB2

1.74e-03205823.40.50.1240
DomainPH_domain

FGD2 SBF2 ARHGEF18 CNKSR2 NIBAN3

1.75e-03280585IPR001849
DomainPH_dom-like

FGD2 SBF2 ARHGEF18 SPRED1 CNKSR2 NIBAN3

2.02e-03426586IPR011993
DomainSAM

SHANK2 PPP1R9A CNKSR2

2.59e-0388583SM00454
DomainSAM_DOMAIN

SHANK2 PPP1R9A CNKSR2

3.21e-0395583PS50105
DomainSAM

SHANK2 PPP1R9A CNKSR2

3.41e-0397583IPR001660
Domain-

SHANK2 PPP1R9A CNKSR2

4.37e-031065831.10.150.50
DomainPH

FGD2 SBF2 ARHGEF18 CNKSR2

5.57e-03229584PF00169
DomainSAM/pointed

SHANK2 PPP1R9A CNKSR2

5.75e-03117583IPR013761
DomainZnf_FYVE

FGD2 SYTL5

6.20e-0338582IPR000306
DomainZF_FYVE

FGD2 SYTL5

6.85e-0340582PS50178
DomainC2

ITCH SYTL5 PRF1

7.86e-03131583PF00168
DomainC2

ITCH SYTL5 PRF1

8.88e-03137583SM00239
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PIK3R4 KAT7 SHANK2 SLC7A6OS SBF2 NFKB2 AMOTL2 PLRG1 GLCCI1 AXIN1 EIF4E2

1.20e-061038591126673895
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR2 SLK ITCH SHANK2 PPP1R9A NUMA1 ARHGEF18 CNKSR2 CTNND2 TNR

4.65e-06963591028671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SLK KANSL1 PPP1R9A PPIP5K1 CNKSR2 ULK2 LARGE1

5.77e-0640759712693553
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK2 PPP1R9A ARHGEF18 CNKSR2 CTNND2 TNR

8.30e-0628159628706196
Pubmed

Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase.

ITCH AXIN1

5.91e-05759228966723
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SLK SHANK2 PPP1R9A CNKSR2 CTNND2

6.85e-0525159527507650
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PIK3R4 KAT7 TGM2 NCOR2 ITCH KANSL1 NFKB2 NUMA1 BIRC6 PLRG1

8.49e-051353591029467282
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PPP1R9A FBF1 PFKFB2 AMOTL2 BIRC6 EIF4E2

1.09e-0444659624255178
Pubmed

A catalogue of genes in mouse embryonal carcinoma F9 cells identified with expressed sequence tags.

KANSL1 PPIP5K1

1.54e-04115928743579
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

KAT7 NUMA1 TMEM209 PLRG1 NUP54

2.52e-0433259525693804
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

SHANK2 CTNND2

2.54e-041459216452088
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PIK3R4 PANK2 KMT5B CAB39L CNKSR2 OSGEP PLRG1 AXIN1 EIF4E2

2.95e-04128459917353931
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PIK3R4 ITCH LARP6 ADAMTS9 SPRED1 STAMBPL1 CTNND2 AMOTL2 ZNF879

2.97e-04128559935914814
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

PANK2 NUMA1 PFKFB2 EIF4E2

3.11e-0419059415161933
Pubmed

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.

NUMA1 TMEM209 CNKSR2 BIRC6 EIF4E2

3.61e-0435959535559673
Pubmed

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

NUMA1 AXIN1

3.79e-041759222153077
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ITCH ADAMTS9 BIRC6 GLCCI1 LARGE1

3.80e-0436359514691545
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NCOR2 SHANK2 KANSL1 KLHL36 SBF2 NFKB2 BIRC6 ULK2

5.34e-04110559835748872
Pubmed

An Alternative Splicing Program for Mouse Craniofacial Development.

SLK NUMA1

5.82e-042159233013468
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PIK3R4 SLK SHANK2 PPP1R12B PPP1R9A CNKSR2 CTNND2 IGLV8-61 TNR

6.48e-04143159937142655
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KANSL1 PPP1R9A BIRC6

7.27e-0410359310574462
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

NCOR2 PPP1R12B FBF1 FGF3 NUP54 EIF4E2

7.41e-0463959623443559
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOR2 NUMA1 ARHGEF18 SLA2 CNKSR2

8.17e-0443059535044719
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

ADAMTS9 AXIN1

8.28e-042559229475039
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TTC8 NCOR2 ITCH SHANK2 SBF2 PPP1R9A ARHGEF18 CAB39L SPIDR

8.59e-04148959928611215
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

NCOR2 NUMA1 ULK2

1.03e-0311659321282530
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

TGM2 NCOR2 GLCCI1

1.08e-0311859330979931
Pubmed

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.

SHANK2 CTNND2

1.12e-032959219208628
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

ITCH NUMA1

1.36e-033259227437069
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SHANK2 PPP1R9A NFKB2 CNKSR2 BIRC6 EIF4E2

1.36e-0371959635337019
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

SHANK2 SRRM4 CTNND2

1.36e-0312859330995482
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ADAMTS9 SBF2 ARHGEF18 SPIDR BIRC6

1.50e-0349359515368895
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

SLK ITCH PPP1R9A CNKSR2 STAMBPL1 PLRG1 EIF4E2

1.52e-03100559719615732
Pubmed

Genomic analysis of mouse retinal development.

PIK3R4 NCOR2 FGF3 PPIP5K1 GLCCI1 AXIN1 LARGE1

1.53e-03100659715226823
Pubmed

Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche.

FGF3 AXIN1

1.53e-033459220883684
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ITCH ADAMTS9 SPRED1 OSGEP BIRC6

1.55e-0349759523414517
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

KAT7 KMT5B

1.62e-033559227142060
Pubmed

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.

PPP1R9A EIF4E2

1.62e-033559237758766
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R12B PPP1R9A SPRED1 AXIN1

6.08e-04181394694
GeneFamilySterile alpha motif domain containing

SHANK2 PPP1R9A CNKSR2

8.97e-0488393760
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD2 SBF2 ARHGEF18 CNKSR2

9.85e-04206394682
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ITCH PRF1

2.73e-0336392823
GeneFamilyPDZ domain containing

SHANK2 PPP1R9A CNKSR2

4.27e-031523931220
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 KANSL1 PPP1R12B SBF2 PPP1R9A SPIDR BIRC6

8.37e-0919959794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 KCNC4 ARHGEF18 TNR NIBAN3

3.17e-0617159520ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SHANK2 PRF1 SLA2 GLCCI1 AXIN1

5.04e-06188595186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHANK2 ADAMTS9 PPP1R9A GLCCI1 LARGE1

5.87e-0619459597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 KANSL1 PPP1R9A SPIDR GLCCI1

6.17e-06196595ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 KANSL1 PPP1R9A SPIDR GLCCI1

6.48e-061985951996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KMT5B ARHGEF18 NIBAN3 LARGE1

2.76e-05131594a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCellLymphoid-B_cells|World / shred on cell class and cell subclass (v4)

B3GNT5 FGD2 NFKB2 NIBAN3

4.33e-05147594aa4486200c523f2c9d3bad7a14f1764c2d92076b
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GNT5 FGD2 ARHGEF18 NIBAN3

4.45e-05148594b78dac56b333bf901136ccafb0999f345e978f51
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

KAT7 KANSL1 PPP1R12B EIF4E2

4.56e-0514959441f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellLymphoid-Lymphoid-B_cells|Lymphoid / shred on cell class and cell subclass (v4)

B3GNT5 FGD2 NFKB2 NIBAN3

4.68e-051505945ebf6b4b9b029422a4676ba09a6a9225bd25db47
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GNT5 FGD2 ARHGEF18 NIBAN3

4.81e-05151594ee56b88c56c3b6a5ec9644c43cae521ea0e05920
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GNT5 FGD2 ARHGEF18 NIBAN3

4.81e-051515942c239b09970acbaa90c5ebe1097f453c516f868e
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GNT5 FGD2 ARHGEF18 NIBAN3

4.93e-05152594b750302d442160a1007659c2386ac90282bf95d2
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

KMT5B ARHGEF18 NIBAN3 LARGE1

5.88e-051595942881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

TTC8 TGM2 PPP1R9A CTNND2

6.47e-051635947f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellfacs-Aorta-Heart-24m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD2 SLA2 CTNND2 NIBAN3

7.11e-05167594b85fd7ab21c80470bca804c788ce49a2bce763f8
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 PRF1 ARHGEF18 SLA2

7.27e-0516859468ef5d1043fca804032669bf990edf110d65cf63
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 KCNC4 ARHGEF18 TNR

7.44e-05169594c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

TGM2 LARP6 SYTL5 TNR

7.61e-0517059497df5ffb328196c46568975d2d97722bcc753bf5
ToppCellImmune_cells-B_cell|Immune_cells / Lineage and Cell class

B3GNT5 FGD2 PFKFB2 NIBAN3

7.97e-05172594b646894b691a99bf2742bd9da8e578dff0e87f1f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 PPIP5K1 CNKSR2 NIBAN3

8.33e-051745946987fe7959afce347282f632abc16d800ccab7c4
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGM2 KCNC4 ADAMTS9 PPP1R12B

8.33e-05174594015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellfacs-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRF1 ARHGEF18 SLA2 CTNND2

8.90e-0517759417065d37fd41f04f67282bee00365daa185e8355
ToppCellfacs-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRF1 ARHGEF18 SLA2 CTNND2

8.90e-051775946e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCellfacs-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRF1 ARHGEF18 SLA2 CTNND2

8.90e-051775949ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-8|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FGD2 PFKFB2 NIBAN3 LARGE1

8.90e-05177594066e7500e7bdde88a7914f50a4661d8adf6db925
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|390C / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 KAT7 SLC7A6OS CNKSR2

9.10e-05178594829ea00c022a78d1861aa3ec53503272976775d9
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

PRF1 FBF1 ZNF324 SLA2

9.29e-0517959410c7d371937d9d93c12c8d3465430ef9e0c2ec81
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

SLA2 PFKFB2 NIBAN3 GLCCI1

9.50e-051805940f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell3'_v3-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

CNKSR2 TNR NIBAN3 LARGE1

9.50e-05180594237a2130a3f48595dad2417539c21e44585962b8
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 FGD2 NIBAN3 GLCCI1

9.50e-05180594b51b10781082bc0305ba6a81e978729b329f7771
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 FGD2 ARHGEF18 NIBAN3

9.70e-05181594ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCellfacs-Heart-LV-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 FGD2 ARHGEF18 ULK2

9.91e-051825946dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

SHANK2 PPP1R9A CTNND2 GLCCI1

1.01e-04183594942530449e9c6583705eeb8f6f12621daea57252
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 CNKSR2 NIBAN3 LARGE1

1.01e-04183594dbc7ec66da5930c2bf4e0405937b054e04c22a34
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SHANK2 KCNC4 PPP1R9A CNKSR2

1.03e-0418459425ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRF1 FBF1 ZNF324 SLA2

1.06e-04185594daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KAT7 KANSL1 PPP1R12B EIF4E2

1.08e-0418659474c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCellBL-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FGD2 TNR NIBAN3 LARGE1

1.08e-0418659427d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FGD2 CNKSR2 TNR NIBAN3

1.10e-041875948fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

FGD2 ARHGEF18 NIBAN3 LARGE1

1.10e-041875944e64be635f445276e71f2937f33f041c3a4204ab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FGD2 CNKSR2 TNR NIBAN3

1.10e-04187594edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

SHANK2 CTNND2 AMOTL2 GLCCI1

1.10e-0418759477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

FGD2 ARHGEF18 NIBAN3 LARGE1

1.10e-04187594af1327559f7e01bec070881cae52834917c3da65
ToppCell(0)_Myeloid-(011)_pDC|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

SLA2 STAMBPL1 PFKFB2 NIBAN3

1.12e-04188594a81b5d840490d6a636fe168f8cff2c4984369f09
ToppCellCOVID-19_Severe-pDC-|COVID-19_Severe / Disease condition and Cell class

SLA2 STAMBPL1 PFKFB2 NIBAN3

1.12e-041885949fd1116e31a05554850b8ed3c005ea660dfbd51c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHANK2 ADAMTS9 GLCCI1 LARGE1

1.12e-0418859463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOVID-19_Severe-pDC|COVID-19_Severe / Disease condition and Cell class

SLA2 STAMBPL1 PFKFB2 NIBAN3

1.12e-04188594475008f45673b42b75ef231c2df91f8b9adc9201
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SHANK2 SYTL5 PPP1R9A CTNND2

1.15e-04189594c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GNT5 FGD2 NIBAN3 GLCCI1

1.19e-041915946729b71fb674aea770a4a3167ccfc07acbf9f302
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A GLCCI1 LARGE1

1.19e-04191594d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A GLCCI1 LARGE1

1.19e-04191594e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-B_cell-B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GNT5 FGD2 NIBAN3 GLCCI1

1.19e-04191594f9fed8dbc4e4e34e59d8c4154e4e3fb320b12257
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 NFKB2 NIBAN3 GLCCI1

1.22e-041925942de242d81dc085ae734eb7d1f091af9a542e0866
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A PFKFB2 GLCCI1

1.22e-0419259429f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A GLCCI1 LARGE1

1.22e-04192594efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT5 NFKB2 NIBAN3 GLCCI1

1.22e-04192594ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KANSL1 SBF2 SPIDR BIRC6

1.24e-04193594779276e775cb2492e8dd36436295a536084a6415
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PPP1R12B PPP1R9A CTNND2 LARGE1

1.24e-04193594dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-pDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLA2 STAMBPL1 PFKFB2 NIBAN3

1.24e-041935942c35aadc397e7e365c3daf8017ae1d3bd045f305
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SHANK2 SRRM4 PPP1R9A CTNND2

1.27e-04194594c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SHANK2 SRRM4 PPP1R9A CTNND2

1.27e-04194594b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PPP1R12B PPP1R9A CTNND2 LARGE1

1.29e-04195594f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SHANK2 PPP1R9A CTNND2 GLCCI1

1.29e-04195594d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

PPP1R12B PPP1R9A CTNND2 LARGE1

1.29e-0419559475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FGD2 CNKSR2 TNR NIBAN3

1.32e-04196594de43dd0697e1daf4d50800957cf0b27b54a7a333
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FGD2 SLA2 STAMBPL1 NIBAN3

1.34e-041975948fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MXRA5 PPP1R12B CAB39L CNKSR2

1.34e-0419759431c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 MXRA5 CTNND2 TNR

1.37e-0419859409be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 LARP6 ADAMTS9 AMOTL2

1.37e-041985949d61483b0decac2fe90045b3474843360b2c49b3
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A CAB39L GLCCI1

1.37e-041985945fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FGD2 SLA2 STAMBPL1 NIBAN3

1.37e-04198594ba3b97bb3e1533df758e845bde7d82eb1525b057
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 LARP6 ADAMTS9 AMOTL2

1.37e-04198594bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FGD2 SLA2 STAMBPL1 NIBAN3

1.37e-04198594436f3a9ef31b0991765bb97c21960f20fa71d578
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHANK2 PPP1R9A CAB39L GLCCI1

1.37e-041985946ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellMS-IIF-Lymphocyte-T/NK-NK_CD56bright|IIF / Disease, condition lineage and cell class

PRF1 SDR42E2 PPP1R9A GLCCI1

1.40e-041995949eb2b7d4900b118338590db778a47504559e228d
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FGD2 SLA2 STAMBPL1 NIBAN3

1.40e-04199594f197ab861767ee06aa47b86c537fb3d8c2b2bc3e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

SLK ITCH SYTL5

4.41e-0411259367b4d2ecc437398c985e6543b82bb593cb164f7f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|356C / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 PRF1 SBF2

5.53e-041215934ec70ad316942d9ade7bbdbf0e117e7c52b59d90
ToppCellBAL-Severe-cDC_6|Severe / Compartment, Disease Groups and Clusters

SDR42E2 PPP1R12B CAB39L

6.81e-041305934104d1e10609331b67db3b85c63537aec58b1713
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

PRF1 SBF2 GLCCI1

6.96e-04131593cc5b5afab8622e98f673fa116a226d930c295327
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7|TCGA-Stomach / Sample_Type by Project: Shred V9

PPP1R12B ARHGEF18 CNKSR2

7.60e-04135593451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCellLPS_only-Myeloid-Dendritic_cells-pDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD2 SLA2 NIBAN3

7.60e-041355930afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRF1 SLA2 AXIN1

8.27e-04139593ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

SYTL5 ZNF879 LARGE1

8.79e-04142593e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

KMT5B ARHGEF18 LARGE1

8.97e-04143593bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 SLA2 TNR

9.34e-0414559307acbf086cffce0628accf078d31bf190f803988
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|368C / Donor, Lineage, Cell class and subclass (all cells)

PRF1 SLA2 STAMBPL1

9.53e-041465930e38e1fa40b1fcd1bb61f7af7cc2206846c192ae
ToppCellURO-Lymphocyte-T_NK-NK_CD56bright|URO / Disease, Lineage and Cell Type

PRF1 PPP1R9A SLA2

9.72e-04147593a6ca90e8dc37a016572ff68f34ab227b020eef70
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

MXRA5 PPP1R12B LARGE1

9.72e-041475938970eb6b82589f39439c61a57d999661ec8342de
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTC8 PRF1 SBF2

9.91e-04148593e7bbb5ddf44b11b8495e83863fbf1fd9f3f24472
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

PRF1 PPP1R12B ZNF879

9.91e-04148593d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

SBF2 SLA2 IGLV8-61

1.03e-03150593c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRF1 ARHGEF18 SLA2

1.03e-031505931f83e3be3f94aefe991a3ccd292c2d11ddef858e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARHGEF18 PPIP5K1 AMOTL2

1.03e-03150593ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRF1 ARHGEF18 SLA2

1.03e-03150593cd666db614bc1b43d71e8eb7bf38cae4d580be80
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRF1 ARHGEF18 SLA2

1.03e-03150593f6ed3e7b36014d1e429b255b0027d89865e1ac07
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV8-61 NIBAN3 LARGE1

1.05e-031515932314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PRF1 SBF2 SLA2

1.05e-03151593512f7f37ddc8dfa1906f7fff92b571929236c9ea
DrugOzagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; MCF7; HT_HG-U133A

LARP6 KLHL36 PPP1R12B ZNF324 OSGEP CTNND2

1.13e-051955963503_DN
DrugPizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A

NCOR2 ADAMTS9 KLHL36 PFKFB2 SPIDR CTNND2

1.23e-051985963134_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; MCF7; HT_HG-U133A

TGM2 SHANK2 KLHL36 PRF1 NFKB2 NUMA1

1.27e-051995966810_DN
Diseasemacula measurement

KANSL1 ADAMTS9 CTNND2 GLCCI1

5.28e-04189584EFO_0008375
Diseaseestradiol measurement

TTC8 SHANK2 PPP1R12B

1.34e-03110583EFO_0004697
Diseasepuberty onset measurement

KANSL1 ZNF324 BIRC6

1.93e-03125583EFO_0005677
DiseaseAbnormality of refraction

PIK3R4 TTC8 ADAMTS9 CNKSR2 CTNND2 BIRC6

2.04e-03673586HP_0000539
Diseaselate-onset Alzheimers disease

SHANK2 KLHL36 CNKSR2 CTNND2

2.62e-03292584EFO_1001870
Diseaseautism spectrum disorder (implicated_via_orthology)

SHANK2 KMT5B CTNND2

3.36e-03152583DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RRQIGTRSPTVEYIS

CAB39L

106

Q9H9S4
ETTTAVTDPRYRARG

AMOTL2

221

Q9Y2J4
TDTGSETPTARRLYT

ERICH1

56

Q86X53
SSSNTIRRPRNYSVG

PFKFB2

471

O60825
GRSRSVPVSFYEIRS

ARHGEF18

151

Q6ZSZ5
YERSRGTPSGTQSSR

BIRC6

4711

Q9NR09
RDIYSRVVASGVPRS

BTBD11

246

A6QL63
TIRRTSSLDTITGPY

GLCCI1

166

Q86VQ1
STIERDRQRPYSSSR

CTNND2

1041

Q9UQB3
ESPSRYQGSRSITPR

RNF212B

136

A8MTL3
QSPSGTRLRREVYSF

NIBAN3

411

Q86XR2
RVPSDSAITYRGSIT

NCOR2

1216

Q9Y618
GTEEPAYSTRRVTRS

KAT7

66

O95251
RQTRVSRPYKISESS

KLHL36

6

Q8N4N3
SPRYTASSQRERESL

LARGE1

51

O95461
ISGSSSRSRPEYFRI

SBF2

1126

Q86WG5
SSPCTYITRRSVRTR

KMT5B

531

Q4FZB7
SRLYRTVSSTPGARR

FGF3

131

P11487
ISTVRGVIVSTRSPY

PLRG1

246

O43660
TSLRRSGSFPVDTQR

PRF1

51

P14222
TSVPPQRRGSRSYRS

KANSL1

936

Q7Z3B3
PDIRRISSRYSQVGT

LARP6

241

Q9BRS8
HRTPLSDSGVTQRYR

OSGEP

311

Q9NPF4
VIYVVERSPNGTSRR

NUP54

241

Q7Z3B4
RLGSYSGPTSVSRQR

PANK2

186

Q9BZ23
RTLIYSTNTRSSGVP

IGLV8-61

71

A0A075B6I0
RRTTTYIDPRTGKSA

ITCH

501

Q96J02
TAPENYDRRSGIRRT

B3GNT5

96

Q9BYG0
APETRRSTYSAPRTQ

ADAMTS9

1171

Q9P2N4
YQPTVVSSEGRQSRR

FBF1

291

Q8TES7
AAPRVSSSRRYSEGR

AXIN1

276

O15169
VGSEPRTVSRRYLNS

FGD2

61

Q7Z6J4
ELYVQSTTRRPRGST

SDR42E2

371

A6NKP2
RRTPGRPTSSQSYEQ

EIF4E2

66

O60573
YRPTTRSSARRSQAG

NUMA1

1876

Q14980
PSTRTVTSVISREYG

SYTL5

266

Q8TDW5
TRTIQRRDSFIGTPY

SLK

181

Q9H2G2
RESQTRRGSYSLSVR

SLA2

121

Q9H6Q3
SGVTFRSPLVTSRAR

RITA1

231

Q96K30
QSRPPDYESRTSGTR

SHANK2

1691

Q9UPX8
RSSSQGRRESTPTYG

CNKSR2

421

Q8WXI2
TTRSILTYSRIGGRV

PIK3R4

1031

Q99570
GRYRVLSSRRSLGTT

SLC7A6OS

101

Q96CW6
CSRRSSPVYVGRVVS

TGM2

211

P21980
YTARPITSSSGRFVR

TTC8

146

Q8TAM2
VPSGTDTTLSRTTYR

ZNF324

61

O75467
DTTLSRTTYRRRNPG

ZNF324

66

O75467
VQRVYSLPSRDSTRG

SPIDR

486

Q14159
TVVTSEPYRSSNIRP

SPRED1

161

Q7Z699
TISEDITPRRYFRSG

STAMBPL1

41

Q96FJ0
TASPLTTSRGRSQEY

SRRM4

271

A7MD48
VSYRPTQVGRLDSSV

TNR

896

Q92752
TVGPVESSGLRSRYR

TMEM209

206

Q96SK2
ESSGLRSRYRSSPTV

TMEM209

211

Q96SK2
QTVGRRLSTGSSRPY

ULK2

461

Q8IYT8
IVSRGRRPRSQQYSV

ZNF879

176

B4DU55
IGSRSSVYSPESSVR

PPIP5K1

226

Q6PFW1
RHETYRSTLRTLPGT

KCNC4

46

Q03721
ARITGTSPRRTDVRY

MXRA5

2146

Q9NR99
IRDRGSSIYRSSSSP

PPP1R12B

461

O60237
QRPSRTRLYDSVSST

PPP1R9A

896

Q9ULJ8
RSLVDTYRQTTSPSG

NFKB2

801

Q00653