Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	AIP3_C	SRCIN1 KIAA1217	2.78e-05	2	99	2	IPR022782
Domain	AIP3	SRCIN1 KIAA1217	2.78e-05	2	99	2	PF03915
Domain	MAP1	MAP1B MAP1S	8.32e-05	3	99	2	IPR026074
Domain	Reticulon	RETREG2 RTN1	5.74e-04	7	99	2	PF02453
Domain	ARM-like	MROH2A HUWE1 RIF1 NBEAL2 AP5Z1 TAF7L HTT	5.86e-04	270	99	7	IPR011989
Domain	Reticulon	RETREG2 RTN1	7.63e-04	8	99	2	IPR003388
Domain	WWE	HUWE1 RNF146	1.77e-03	12	99	2	PS50918
Domain	WWE	HUWE1 RNF146	1.77e-03	12	99	2	PF02825
Domain	WWE-dom	HUWE1 RNF146	1.77e-03	12	99	2	IPR004170
Domain	ARM-type_fold	MROH2A INTS1 HUWE1 NCDN RIF1 NBEAL2 HTT	2.18e-03	339	99	7	IPR016024
Domain	AT_hook	PHF21A KMT2C	3.18e-03	16	99	2	PF02178
Domain	-	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.21e-03	679	99	10	3.30.160.60
Domain	Znf_C2H2-like	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 ZNF750 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.26e-03	796	99	11	IPR015880
Domain	Znf_C2H2	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 ZNF750 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.55e-03	805	99	11	IPR007087
Domain	ZnF_C2H2	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 ZNF750 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.65e-03	808	99	11	SM00355
Domain	zf-C2H2	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.70e-03	693	99	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	3.74e-03	694	99	10	IPR013087
Domain	CONNEXINS_1	GJA3 GJA10	4.48e-03	19	99	2	PS00407
Domain	CONNEXINS_2	GJA3 GJA10	4.97e-03	20	99	2	PS00408
Domain	Connexin	GJA3 GJA10	4.97e-03	20	99	2	IPR000500
Domain	Connexin_CCC	GJA3 GJA10	4.97e-03	20	99	2	IPR019570
Domain	Connexin_N	GJA3 GJA10	4.97e-03	20	99	2	IPR013092
Domain	Connexin	GJA3 GJA10	4.97e-03	20	99	2	PF00029
Domain	Connexin_CCC	GJA3 GJA10	4.97e-03	20	99	2	SM01089
Domain	Connexin_CS	GJA3 GJA10	4.97e-03	20	99	2	IPR017990
Domain	-	MAP1B MAP1S	4.97e-03	20	99	2	3.60.15.10
Domain	Metallo-B-lactamas	MAP1B MAP1S	4.97e-03	20	99	2	IPR001279
Domain	CNX	GJA3 GJA10	4.97e-03	20	99	2	SM00037
Domain	PWWP	ZCWPW2 PWWP2B	6.54e-03	23	99	2	PF00855
Domain	PWWP_dom	ZCWPW2 PWWP2B	6.54e-03	23	99	2	IPR000313
Domain	PDZ	SIPA1L3 APBA2 PDZD7 AHNAK2	6.74e-03	141	99	4	PF00595
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SIPA1L3 INTS1 LMTK2 GBX2 HUWE1 MDFI ITGA5 KIFC2 MAPK8IP3 HIVEP3 KMT2C PWWP2B MAP1S SGSM2 NBEAL2 PPP1R15B FLCN PDCD11 TANC1 HTT AHNAK2	1.78e-11	1105	106	21	35748872
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ANK3 MAP1B SIPA1L3 SRCIN1 HUWE1 CHRM3 SH2B1 NCDN MAPK8IP3 HIVEP3 KMT2C PTPDC1 PWWP2B SGSM2 KIAA1217 LRRC27 SEMA6A TANC1 HTT	1.15e-07	1489	106	19	28611215
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ANK3 RRP1B PPP1R12B SIPA1L3 LMTK2 HUWE1 ITGA5 PPM1J LUZP1 PTPDC1 RIF1 TOX4 CSPG5 SLTM TANC1 CRYBG3	1.22e-07	1049	106	16	27880917
Pubmed	Protein phosphatase 1γ isoforms linked interactions in the brain.	RRP1B LMTK2 ZDBF2 RIF1 PPP1R15B	8.83e-07	57	106	5	23080069
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ANK3 APBA2 KIAA1217 PLEKHA5 TANC1 CRYBG3 GOLGA2 AHNAK2	1.53e-06	263	106	8	34702444
Pubmed	A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia.	CCDC170 ZBTB2 AKAP12	2.28e-06	9	106	3	21540461
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	SIPA1L3 ZDBF2 RTN1 LUZP1 PLEKHA5 TANC1 CRYBG3	3.77e-06	209	106	7	36779422
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RRP1B LMTK2 SRCIN1 PHF21A KMT2C NBEAL2 AP5Z1 PDCD11 PLEKHA5 ZNF646	5.26e-06	529	106	10	14621295
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 ZDBF2 E2F6 HUWE1 PHF21A LUZP1 TOX4 PLEKHA5 CRYBG3	5.64e-06	418	106	9	34709266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANK3 SIPA1L3 SIRPB1 HUWE1 RTN1 NCDN AKAP12 LUZP1 MAPK8IP3 KIAA1217 PDE4DIP PLEKHA5 GOLGA2	7.68e-06	963	106	13	28671696
Pubmed	Chromosome assignment of human brain expressed sequence tags (ESTs) by analyzing fluorescently labeled PCR products from hybrid cell panels.	MAP1B TST	9.20e-06	2	106	2	8404072
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RETREG2 ANK3 MAP1B APBA2 LMTK2 ZDBF2 SRCIN1 HUWE1 RTN1 MAPK8IP3 MAP1S KIAA1217 PDE4DIP CRYBG3	9.67e-06	1139	106	14	36417873
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP1B NTRK3 SIPA1L3 ZNF629 LMTK2 MAP3K6 LUZP1 KIAA1217 PLEKHA5 TANC1 CRYBG3 AHNAK2	1.28e-05	861	106	12	36931259
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RRP1B PPP1R12B LMTK2 RIF1 TOX4 KIAA1217 PPP1R15B PDCD11	1.55e-05	361	106	8	30344098
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SRCIN1 PHF21A LRRC27 PLEKHA5 TANC1	1.57e-05	102	106	5	11214970
Pubmed	Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.	MAP1S HTT	2.76e-05	3	106	2	26540094
Pubmed	RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics.	MAP1B MAP1S	2.76e-05	3	106	2	15205320
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK3 MAP1B PPP1R12B SIPA1L3 SRCIN1 RTN1 NCDN LUZP1 MAPK8IP3 GJA3 MAP1S KIAA1217 PDE4DIP PLEKHA5 TANC1	2.94e-05	1431	106	15	37142655
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	MAP1B LUZP1 KIAA1217 GOLGA2 AHNAK2	3.18e-05	118	106	5	30979931
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GBX2 E2F6 PHF21A OVOL2 HIVEP3 ZNF750 RIF1 TOX4 SLTM ZNF76 ZNF646	3.73e-05	808	106	11	20412781
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ANK3 MAP1B HUWE1 LUZP1 KMT2C TOX4 PDCD11 PLEKHA5 HTT	4.82e-05	549	106	9	38280479
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ANK3 SIPA1L3 SRCIN1 LUZP1 KIAA1217 NECTIN4 PLEKHA5 TANC1 GOLGA2	6.01e-05	565	106	9	25468996
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ASXL1 ZNF536 ZBTB2 MAP1B E2F6 HUWE1 SH2B1 PHF21A RIF1 AP5Z1 ZBTB40	6.32e-05	857	106	11	25609649
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	MAP1B RRP1B PPP1R12B INTS1 LMTK2 RIF1 TOX4 MAP1S PPP1R15B	6.69e-05	573	106	9	28330616
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZNF629 ZDBF2 HUWE1 LUZP1 GSR KIAA1217 TANC1 CRYBG3 GOLGA2	8.14e-05	588	106	9	38580884
Pubmed	Identification of Arx transcriptional targets in the developing basal forebrain.	MAGEL2 GBX2 PDE4DIP	8.53e-05	28	106	3	18799476
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ANK3 RRP1B SIPA1L3 ITGA5 MAP1S SLTM PLEKHA5	1.24e-04	361	106	7	26167880
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	ZDBF2 LUZP1 PLEKHA5 TANC1 GOLGA2 AHNAK2	1.38e-04	256	106	6	33397691
Pubmed	Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.	MAP1B NCDN HTT	1.40e-04	33	106	3	26025364
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 ZBTB2 ZNF629 APBA2 SIRPB1 PHF21A LUZP1 PWWP2B TAF7L TANC1 CRYBG3 ZNF646	1.55e-04	1116	106	12	31753913
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	ASXL1 MAP1B ZDBF2 HIVEP3	1.70e-04	90	106	4	15033168
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAP1B ZNF629 MAP3K6 NCDN SLTM PLEKHA5 TANC1 CRYBG3 GOLGA2	1.73e-04	650	106	9	38777146
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	MAP1B RRP1B LMTK2 RIF1 TOX4 MAP1S	1.85e-04	270	106	6	24366813
Pubmed	Functional significance of gap junctional coupling in preimplantation development.	GJA3 GJA10	1.91e-04	7	106	2	11967204
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	NTRK3 MDFI EDA TOX4 PDE4DIP GOLGA2 HTT	2.39e-04	402	106	7	24722188
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	SIPA1L3 PHF21A CYB5B RIF1 GZF1 KIAA1217 PLEKHA5 TANC1	2.43e-04	536	106	8	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	SIPA1L3 PHF21A CYB5B RIF1 GZF1 KIAA1217 PLEKHA5 TANC1	2.49e-04	538	106	8	10512203
Pubmed	Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice.	MAP1B MAP1S	2.55e-04	8	106	2	21486449
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ZBTB2 MIER3 HUWE1 PHF21A RIF1 PDCD11	2.66e-04	289	106	6	23752268
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZNF536 ZNF629 HUWE1 ZNF646	2.97e-04	104	106	4	9205841
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SIPA1L3 NCDN NBEAL2 GPRIN2	3.08e-04	105	106	4	9628581
Pubmed	Identification and characterization of novel substrates of Trk receptors in developing neurons.	NTRK3 SH2B1	3.27e-04	9	106	2	9856458
Pubmed	Identification of novel germline polymorphisms governing capecitabine sensitivity.	GJA3 PDE4DIP	3.27e-04	9	106	2	22864933
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	INTS1 ZNF629 ZDBF2 E2F6 HUWE1 RIF1 PDCD11 ZNF646	4.25e-04	583	106	8	29844126
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MAP1B RRP1B INTS1 MAP3K6 LUZP1 CYB5B MAP1S PDE4DIP FLCN GOLGA2	4.74e-04	910	106	10	36736316
Pubmed	Multiple genetic loci for bone mineral density and fractures.	CCDC170 ZBTB40	4.97e-04	11	106	2	18445777
Pubmed	Proteomic analysis of in vivo phosphorylated synaptic proteins.	MAP1B SRCIN1 RTN1	5.77e-04	53	106	3	15572359
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	RRP1B ZDBF2 E2F6 PHF21A TOX4 PDCD11	6.18e-04	339	106	6	30415952
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ASXL1 SIPA1L3 KMT2C ZBTB40 PLEKHA5	6.46e-04	225	106	5	12168954
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	MAP1S PPP1R15B FLCN TANC1	6.51e-04	128	106	4	25332235
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	PPP1R12B PDE4DIP ZBTB40	6.78e-04	56	106	3	9455484
Pubmed	Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.	ANK3 GBX2	7.02e-04	13	106	2	15931389
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	MAP1B RRP1B HUWE1 SLTM PDCD11 ZNF646	7.19e-04	349	106	6	25665578
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MAP1B PODXL2 SRCIN1 LUZP1 MAPK8IP3	7.28e-04	231	106	5	16452087
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PDZD7 AKAP12 KMT2C RIF1 PDE4DIP	7.56e-04	233	106	5	37704626
Pubmed	Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain.	GBX2 SEMA6A	8.18e-04	14	106	2	22821687
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ANK3 SRCIN1 KMT2C MAP1S NBEAL2 PLEKHA5 GOLGA2	8.42e-04	497	106	7	36774506
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	AKAP12 LUZP1 KIAA1217 PLEKHA5 GOLGA2 AHNAK2	8.44e-04	360	106	6	33111431
Pubmed	Characterization of the murine mafF gene.	TST KIFC2	9.41e-04	15	106	2	10409670
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM64 TRIM64B	9.41e-04	15	106	2	19703589
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	ZBTB2 GZF1 ZBTB40	9.57e-04	63	106	3	34351428
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	MAP1B APBA2 SRCIN1 HUWE1 AKAP12	9.64e-04	246	106	5	15345747
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	ZBTB2 INTS1 KMT2C KIAA1217	1.06e-03	146	106	4	23892456
Pubmed	Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.	MAGEL2 MAP1B	1.07e-03	16	106	2	19627984
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	RRP1B RIF1	1.07e-03	16	106	2	29764992
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	MAP1B PPP1R12B SRCIN1	1.14e-03	67	106	3	29254152
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	MAP1B HUWE1 GSR RIF1 RNF146	1.15e-03	256	106	5	32698014
Pubmed	Identification of the human testis protein phosphatase 1 interactome.	LMTK2 RIF1 PPP1R15B	1.19e-03	68	106	3	21382349
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	HUWE1 ZBTB40	1.21e-03	17	106	2	28169274
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	MAP1B INTS1 SRCIN1 EDA AKAP12 KMT2C PDE4DIP ZNF646	1.25e-03	689	106	8	36543142
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	HUWE1 RTN1 AKAP12 RIF1	1.26e-03	153	106	4	26365490
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	INTS1 SH2B1 SEMA6A MUC20	1.26e-03	153	106	4	10718198
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	RIF1 KIAA1217 CRYBG3	1.35e-03	71	106	3	33541421
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	MAP1B LUZP1 TANC1 CRYBG3	1.36e-03	156	106	4	32850835
Pubmed	An expression atlas of connexin genes in the mouse.	GJA3 GJA10	1.36e-03	18	106	2	15081111
Pubmed	The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice.	GBX2 SEMA6A	1.36e-03	18	106	2	12421703
Pubmed	The novel mouse connexin39 gene is expressed in developing striated muscle fibers.	GJA3 GJA10	1.36e-03	18	106	2	15466892
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	INTS1 ZDBF2 RIF1 PDCD11 KIAA2012	1.50e-03	272	106	5	31010829
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM64 TRIM64B	1.52e-03	19	106	2	22144910
Pubmed	An update on connexin genes and their nomenclature in mouse and man.	GJA3 GJA10	1.52e-03	19	106	2	14681012
Pubmed	Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers.	NTRK3 NHLH1	1.52e-03	19	106	2	32880858
Pubmed	Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2.	GBX2 SEMA6A	1.52e-03	19	106	2	17493606
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	ASXL1 KMT2C	1.69e-03	20	106	2	29785026
Pubmed	Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.	C14orf93 EDA	1.69e-03	20	106	2	23704328
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK3 NTRK3 SRCIN1 NCDN LUZP1	1.73e-03	281	106	5	28706196
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANK3 LMTK2 HUWE1 KIFC2 NCDN AKAP12 ZNF750 KMT2C SLTM ZBTB40	1.78e-03	1084	106	10	11544199
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	ZDBF2 AKAP12 LUZP1 CYB5B TANC1 GOLGA2 AHNAK2	1.81e-03	568	106	7	37774976
Pubmed	Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.	RRP1B SEMA6A	1.86e-03	21	106	2	25017104
Pubmed	Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.	CCDC170 ZBTB40	1.86e-03	21	106	2	24249740
Pubmed	Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1.	NPPB NTRK3	1.86e-03	21	106	2	28476948
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ANK3 SIPA1L3 APBA2 CLIC6 HUWE1 SH2B1 MAPK8IP3 MAP1S SGSM2 PDE4DIP ZNF76	1.89e-03	1285	106	11	35914814
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ANK3 RRP1B E2F6 NCDN AKAP12 GSR PPP1R15B PDCD11 PLEKHA5 SEMA6A TANC1 CRYBG3	1.93e-03	1487	106	12	33957083
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	C14orf93 RRP1B INTS1 ZNF629 E2F6 PHF21A KMT2C RIF1 TOX4 SLTM PDCD11	2.00e-03	1294	106	11	30804502
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	RRP1B ZDBF2 HUWE1 RTN1 LUZP1 CYB5B KIAA1217 PPP1R15B PDCD11 TANC1 CRYBG3 AHNAK2	2.03e-03	1496	106	12	32877691
Pubmed	Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.	HUWE1 RTN1	2.04e-03	22	106	2	37225996
Pubmed	Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes.	GBX2 SEMA6A	2.23e-03	23	106	2	27655933
Pubmed	The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy.	NPPB E2F6	2.23e-03	23	106	2	22403008
Pubmed	Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.	PDE4DIP GOLGA2	2.23e-03	23	106	2	22792062
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MAP1B RTN1 PHF21A AKAP12 GSR RIF1 TOX4 KIAA1217 AHNAK2	2.25e-03	934	106	9	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HUWE1 MAPK8IP3 TANC1	2.42e-03	87	106	3	12465718
Interaction	ZYX interactions	SIPA1L3 RTN1 PHF21A LUZP1 KIAA1217 PLEKHA5 TANC1 CRYBG3 GOLGA2 AHNAK2	6.62e-06	329	102	10	int:ZYX
Interaction	TOP3B interactions	SIPA1L3 INTS1 LMTK2 GBX2 HUWE1 MDFI ITGA5 KIFC2 MAPK8IP3 HIVEP3 KMT2C PWWP2B MAP1S SGSM2 NBEAL2 PPP1R15B FLCN PDCD11 TANC1 HTT AHNAK2	1.22e-05	1470	102	21	int:TOP3B
Interaction	MAPRE3 interactions	SIPA1L3 LUZP1 MAP1S KIAA1217 PDE4DIP PLEKHA5 TANC1 GOLGA2	2.22e-05	230	102	8	int:MAPRE3
Cytoband	15q11-q12	MAGEL2 APBA2	5.26e-05	5	106	2	15q11-q12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF536 ZBTB2 ZNF629 OVOL2 HIVEP3 GZF1 ZBTB40 ZNF76 ZNF79 ZNF646	2.27e-04	718	65	10	28
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAP1B RRP1B PPP1R12B LMTK2 PPP1R15B	4.83e-04	181	65	5	694
GeneFamily	PDZ domain containing	SIPA1L3 APBA2 PDZD7 AHNAK2	2.18e-03	152	65	4	1220
GeneFamily	Gap junction proteins	GJA3 GJA10	2.81e-03	22	65	2	314
GeneFamily	PWWP domain containing	ZCWPW2 PWWP2B	2.81e-03	22	65	2	1147
GeneFamily	DNA polymerases	POLG2 POLQ	3.07e-03	23	65	2	535
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SIPA1L3 CLIC6 TST OVOL2 ZNF750 PWWP2B NECTIN4 ZNF76	2.35e-08	196	106	8	547901c7a665770eff78eede69b8625b416c8186
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SIPA1L3 CLIC6 TST OVOL2 ZNF750 PWWP2B NECTIN4 ZNF76	2.35e-08	196	106	8	6e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NPPB ZNF536 ANK3 PPP1R12B EDA PDE4DIP TANC1	4.23e-07	194	106	7	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 ANK3 MAP1B SRCIN1 RTN1 HIVEP3 PDE4DIP	5.19e-07	200	106	7	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANK3 SRCIN1 CLIC6 KIAA1217 NECTIN4 TANC1	3.32e-06	170	106	6	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 LMTK2 SGSM2 KIAA1217 NECTIN4 TANC1	4.47e-06	179	106	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 NECTIN4 TANC1	5.57e-06	186	106	6	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	droplet-Heart-HEART-1m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 ANK3 PCDHGB6 NTRK3 SRCIN1 CSPG5	5.57e-06	186	106	6	fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PODXL2 RTN1 KIFC2 NCDN SGSM2	5.75e-06	187	106	6	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PODXL2 RTN1 KIFC2 NCDN SGSM2	5.75e-06	187	106	6	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PODXL2 RTN1 KIFC2 NCDN SGSM2	5.75e-06	187	106	6	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ANK3 SIPA1L3 CHRM3 KIAA1217 SEMA6A TANC1	5.93e-06	188	106	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 PLEKHA5 TANC1	7.30e-06	195	106	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 PLEKHA5 TANC1	7.30e-06	195	106	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 MAP1B RTN1 NCDN HIVEP3 PDE4DIP	8.44e-06	200	106	6	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SRCIN1 SIRPB1 ITGA5 MAP1S RNF146	2.62e-05	146	106	5	1e81ad3d6d5d5ad2f0176d2a9593a954d38fa294
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHRM3 VWDE ZNF750 NECTIN4 MUC20	3.82e-05	158	106	5	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 MAP1B RTN1 NCDN	4.01e-05	80	106	4	5c39136f5f855efbf61e1f5348ea97ea2130b241
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ZNF536 PPP1R12B MIER3 PDZD7 CHRM3	4.43e-05	163	106	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PCDHGB6 RRP1B MAP1S NECTIN4 ZNF79	5.11e-05	168	106	5	2fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RTN1 SEMA6A TANC1 CRYBG3 POLQ	5.26e-05	169	106	5	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 ANK3 APBA2 SRCIN1 EDA	6.72e-05	178	106	5	3e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	ITGA5 EDA CHRM3 KIAA1217 SEMA6A	7.09e-05	180	106	5	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	15-Distal-Epithelial-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	ANK3 SRCIN1 RTN1 NHLH1 ZNF79	7.09e-05	180	106	5	99e2db9ad8e09fedc3542233553acece69f579f1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF536 MAP1B PPP1R12B AKAP12 AHNAK2	7.66e-05	183	106	5	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF536 NCDN TANC1 CRYBG3 ZNF646	7.86e-05	184	106	5	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	NPPB ANK3 PPP1R12B PDE4DIP PLEKHA5	7.86e-05	184	106	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF536 ANK3 MAP1B NTRK3 PPP1R12B	8.27e-05	186	106	5	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	8.27e-05	186	106	5	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NPPB ANK3 PPP1R12B PDE4DIP TANC1	8.70e-05	188	106	5	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ASXL1 ZCWPW2 ANK3 APBA2 TANC1	8.70e-05	188	106	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EDA RTN1 KIAA1217 SEMA6A TANC1	8.92e-05	189	106	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 ANK3 RTN1 PWWP2B NHLH1	8.92e-05	189	106	5	3717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	8.92e-05	189	106	5	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK3 MAPK8IP3 KIAA1217 PDE4DIP TANC1	8.92e-05	189	106	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EDA CHRM3 KIAA1217 SEMA6A TANC1	9.14e-05	190	106	5	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EDA CHRM3 KIAA1217 SEMA6A TANC1	9.14e-05	190	106	5	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	ZCWPW2 CLIC6 KIAA1217 NECTIN4 TANC1	9.37e-05	191	106	5	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	NPPB ANK3 PPP1R12B PDE4DIP TANC1	9.37e-05	191	106	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	9.37e-05	191	106	5	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EDA CHRM3 KIAA1217 SEMA6A TANC1	9.37e-05	191	106	5	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	ZCWPW2 AKAP12 KIAA1217 SEMA6A TANC1	9.37e-05	191	106	5	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLIC6 OVOL2 ZNF750 KIAA1217 AHNAK2	9.60e-05	192	106	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	9.60e-05	192	106	5	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ASXL1 ITGA5 AKAP12 LUZP1 PPP1R15B	9.60e-05	192	106	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLIC6 OVOL2 ZNF750 KIAA1217 AHNAK2	9.60e-05	192	106	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	COPD-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	ZCWPW2 MAP1B AKAP12 SEMA6A TANC1	9.84e-05	193	106	5	25bdc557055b5bce6a21f8696b48e991c696b979
ToppCell	15\|World / Age, Tissue, Lineage and Cell class	NTRK3 CLIC6 RTN1 NECTIN4 MUC20	9.84e-05	193	106	5	a8ad0de955494d6f5929dc44ba46627d06d95453
ToppCell	Control-Endothelial-Lymphatic\|Control / Disease state, Lineage and Cell class	ZCWPW2 MAP1B AKAP12 SEMA6A TANC1	9.84e-05	193	106	5	64d19be73e5432d491436a01da5de5c926b615a9
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	ZCWPW2 AKAP12 KIAA1217 SEMA6A TANC1	9.84e-05	193	106	5	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPP1R12B MDFI KIAA1217 PLEKHA5 AHNAK2	9.84e-05	193	106	5	739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 CLIC6 MDFI NECTIN4 MUC20	9.84e-05	193	106	5	22ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC170 MAP1B AKAP12 KIAA1217 TANC1	1.01e-04	194	106	5	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC170 MAP1B AKAP12 KIAA1217 TANC1	1.01e-04	194	106	5	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ANK3 PPP1R12B EDA PDE4DIP TANC1	1.01e-04	194	106	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	ZCWPW2 AKAP12 KIAA1217 SEMA6A TANC1	1.01e-04	194	106	5	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	Differ-Basal\|World / shred by cell class for mouse tongue	ANK3 TST MAP3K6 GSR SEMA6A	1.01e-04	194	106	5	851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	1.03e-04	195	106	5	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 PLEKHA5	1.03e-04	195	106	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANK3 CLIC6 OVOL2 KIAA1217 NECTIN4	1.03e-04	195	106	5	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	1.03e-04	195	106	5	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	ANK3 CLIC6 KIAA1217 TANC1 LRRC36	1.03e-04	195	106	5	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	1.06e-04	196	106	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANK3 MAP1B PODXL2 RTN1 NCDN	1.06e-04	196	106	5	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1B NTRK3 MDFI CHRM3 KIAA1217	1.06e-04	196	106	5	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	ZCWPW2 ANK3 CLIC6 KIAA1217 TANC1	1.06e-04	196	106	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	droplet-Tongue-nan-3m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TST MAP3K6 ZNF750 NECTIN4 SEMA6A	1.06e-04	196	106	5	159061fd0961b2cfb5941d403acc5b395dd0d3a0
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	EDA CHRM3 RTN1 KIAA1217 SEMA6A	1.06e-04	196	106	5	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF536 MAP1B NTRK3 ITGA5 AKAP12	1.08e-04	197	106	5	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF629 AKAP12 KMT2C SEMA6A POLQ	1.08e-04	197	106	5	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B PPP1R12B ITGA5 AKAP12 AHNAK2	1.08e-04	197	106	5	ba6393671a980a1d439307601d18db70a1b1e1f3
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZNF536 ANK3 MAP1B AKAP12 KIAA1217	1.08e-04	197	106	5	b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ANK3 MDFI HIVEP3 PLEKHA5 TANC1	1.08e-04	197	106	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 CLIC6 CHRM3 KIAA1217 NECTIN4	1.11e-04	198	106	5	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK3 MAP1B CHRM3 RTN1 PLEKHA5	1.11e-04	198	106	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC170 ANK3 GSR KIAA2012 MUC20	1.11e-04	198	106	5	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	Transverse-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	AMZ1 SIRPB1 MDFI AKAP12 POLQ	1.14e-04	199	106	5	7cfe9b2538ea008d67343f3e8bfec3bf81200de6
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MDFI ZNF750 NECTIN4 PLEKHA5 AHNAK2	1.14e-04	199	106	5	974f71b56f66243c78f2f297a1540e0e186df530
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1B NTRK3 ZNF629 PDZD7 AKAP12	1.14e-04	199	106	5	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B ITGA5 MAP3K6 AKAP12 AHNAK2	1.14e-04	199	106	5	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 PPP1R12B SIPA1L3 CHRM3 KMT2C	1.14e-04	199	106	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 MAP1B RTN1 HIVEP3 PDE4DIP	1.14e-04	199	106	5	a255484ba77bd2741a541da278efc8cf4abbe570
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 RTN1 NCDN PDE4DIP SEMA6A	1.16e-04	200	106	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 SIPA1L3 KIAA1217 SEMA6A CRYBG3	1.16e-04	200	106	5	f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANK3 KIAA1217 NECTIN4 AHNAK2 MUC20	1.16e-04	200	106	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 KIAA1217 NECTIN4 PLEKHA5 MUC20	1.16e-04	200	106	5	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	ANK3 MAP1B CHRM3 RTN1 PLEKHA5	1.16e-04	200	106	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 SIPA1L3 KIAA1217 SEMA6A CRYBG3	1.16e-04	200	106	5	70a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 RTN1 NCDN PDE4DIP SEMA6A	1.16e-04	200	106	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF536 SIPA1L3 KIAA1217 SEMA6A CRYBG3	1.16e-04	200	106	5	1639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 KIAA1217 NECTIN4 AHNAK2 MUC20	1.16e-04	200	106	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 CHRM3 RTN1 KIAA1217 TANC1	1.16e-04	200	106	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF536 ZDBF2 CHRM3 POLQ	2.00e-04	121	106	4	da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CLIC6 MDFI ZNF750 AHNAK2	2.20e-04	124	106	4	b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CLIC6 MDFI ZNF750 AHNAK2	2.20e-04	124	106	4	231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCell	ASK452-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	C14orf93 NTRK3 SGSM2 ZNF79	2.79e-04	132	106	4	49ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCell	RV-05._Cytoplasmic_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	MROH2A PDZD7 TSSC4 GPRIN2	3.21e-04	137	106	4	97f090732bc73db1cff050b1d6380b5ecc9a95e5
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	TRIM64B MALRD1 LINC00208 KIAA2012	3.40e-04	139	106	4	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ZCWPW2 ZDBF2 ITGA5 CHRM3	3.68e-04	142	106	4	85e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 RTN1 NCDN	3.75e-04	59	106	3	74590437b1d9a2a8fe56d79b2e66803528b81298
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A	MAP1B RRP1B NTRK3 SIPA1L3 LUZP1 HIVEP3 SGSM2 AP5Z1 ZNF646	2.28e-07	194	102	9	3404_UP
Drug	PNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A	SIPA1L3 MDFI CHRM3 MAPK8IP3 RIF1 SGSM2 RNF146 ZNF76 GOLGA2	2.38e-07	195	102	9	3735_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	ANK3 TSSC4 SH2B1 HIVEP3 MAP1S AP5Z1 FLCN PDCD11 ZNF79	2.70e-07	198	102	9	4800_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	ASXL1 TSSC4 NCDN MAPK8IP3 MAP1S NBEAL2 PDE4DIP ZNF79	2.98e-06	197	102	8	5211_DN
Drug	SR-95639A [115767-94-7]; Down 200; 10uM; MCF7; HT_HG-U133A	C14orf93 ANK3 CHRM3 HIVEP3 ZNF750 AP5Z1 PDE4DIP GOLGA2	2.98e-06	197	102	8	4977_DN
Drug	rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A	APBA2 EDA LUZP1 MAPK8IP3 AP5Z1 PDE4DIP FLCN GPRIN2	3.21e-06	199	102	8	5975_DN
Drug	sodium tellurite	GSR SEMA6A	1.99e-05	2	102	2	CID000024935
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	C14orf93 SIPA1L3 SH2B1 PDE4DIP ZNF76 ZNF79 GOLGA2	2.23e-05	188	102	7	1023_UP
Drug	Roxithromycin [80214-83-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 EDA MAPK8IP3 AP5Z1 ZNF76 ZNF646	2.91e-05	196	102	7	3331_UP
Drug	Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A	MAP1B SH2B1 LUZP1 PDE4DIP ZNF76 ZNF79 GPRIN2	3.01e-05	197	102	7	5349_UP
Drug	Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; PC3; HT_HG-U133A	C14orf93 INTS1 EDA RTN1 SH2B1 MAPK8IP3 PDE4DIP	3.01e-05	197	102	7	4625_UP
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	ANK3 RRP1B EDA AKAP12 MAPK8IP3 HIVEP3 SEMA6A	3.01e-05	197	102	7	7521_UP
Drug	Halcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	C14orf93 SIPA1L3 APBA2 MAP3K6 AKAP12 LUZP1 ZNF79	3.11e-05	198	102	7	4703_DN
Drug	nitrendipine; Down 200; 10uM; MCF7; HG-U133A	NPPB TSSC4 MAP3K6 EDA AKAP12 LUZP1 PDE4DIP	3.11e-05	198	102	7	336_DN
Drug	(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; HL60; HT_HG-U133A	C14orf93 IRF7 NBEAL2 PDE4DIP PDCD11 ZNF76 HTT	3.11e-05	198	102	7	2961_DN
Drug	Flucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A	C14orf93 PODXL2 MAPK8IP3 HIVEP3 SGSM2 AP5Z1 ZNF79	3.32e-05	200	102	7	6690_DN
Drug	Letrozole [112809-51-5]; Down 200; 14uM; MCF7; HT_HG-U133A	MAP1B APBA2 LUZP1 HIVEP3 SGSM2 ZBTB40 FLCN	3.32e-05	200	102	7	4824_DN
Drug	4,4'-diaminodibenzyl	EDA SEMA6A	1.19e-04	4	102	2	CID000012138
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1B IRF7 AKAP12 AP5Z1 PDE4DIP AHNAK2	1.52e-04	178	102	6	5693_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	MAP1B IRF7 AKAP12 AP5Z1 PDE4DIP AHNAK2	1.57e-04	179	102	6	6951_UP
Drug	SAHA; Up 200; 10uM; MCF7; HT_HG-U133A	MAP1B IRF7 AKAP12 LUZP1 PDE4DIP AHNAK2	1.61e-04	180	102	6	6939_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	MAP1B IRF7 AKAP12 AP5Z1 PDE4DIP AHNAK2	1.61e-04	180	102	6	6579_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1B EDA AKAP12 PDE4DIP SEMA6A AHNAK2	1.66e-04	181	102	6	2881_UP
Drug	Dequalinium dichloride [522-51-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A	LUZP1 ZNF750 PDE4DIP ZNF76 GPRIN2 ZNF646	1.99e-04	187	102	6	5396_UP
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	C14orf93 CHRM3 SH2B1 PDE4DIP FLCN AHNAK2	2.04e-04	188	102	6	1667_UP
Drug	2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA	MAP1B PHF21A MAPK8IP3 CSPG5 PDE4DIP AHNAK2	2.10e-04	189	102	6	989_UP
Drug	Isoflupredone acetate [338-98-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	RRP1B GBX2 NCDN AP5Z1 ZBTB40 ZNF79	2.10e-04	189	102	6	1832_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	C14orf93 ANK3 SH2B1 ZBTB40 GOLGA2 AHNAK2	2.10e-04	189	102	6	1646_UP
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	ZBTB40 PDCD11 ZNF76 ZNF79 GOLGA2 GPRIN2	2.23e-04	191	102	6	5234_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A	GBX2 SH2B1 HIVEP3 AP5Z1 RNF146 ZNF76	2.23e-04	191	102	6	3665_DN
Drug	Thiostrepton [1393-48-2]; Down 200; 2.4uM; PC3; HT_HG-U133A	PPP1R12B ZNF629 CSPG5 ZNF76 ZNF79 AHNAK2	2.23e-04	191	102	6	4563_DN
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Up 200; 100uM; MCF7; HT_HG-U133A_EA	NPPB MAP1B CHRM3 MAPK8IP3 AP5Z1 ZNF79	2.35e-04	193	102	6	881_UP
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A	PODXL2 AKAP12 MAPK8IP3 PDE4DIP ZNF76 GOLGA2	2.35e-04	193	102	6	2078_UP
Drug	Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; PC3; HT_HG-U133A	ANK3 SIPA1L3 GBX2 MDFI ZNF76 GOLGA2	2.35e-04	193	102	6	4671_DN
Drug	Colchicine [64-86-8]; Down 200; 10uM; MCF7; HT_HG-U133A	NCDN AKAP12 TOX4 RNF146 PDE4DIP ZNF79	2.35e-04	193	102	6	3213_DN
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	C14orf93 MAP1B INTS1 LMTK2 EDA ZNF76	2.42e-04	194	102	6	3285_UP
Drug	Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	RETREG2 ZNF629 IRF7 MAPK8IP3 NBEAL2 PDE4DIP	2.42e-04	194	102	6	7423_DN
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	PODXL2 HUWE1 HIVEP3 ZBTB40 ZNF76 GOLGA2	2.49e-04	195	102	6	5265_UP
Drug	Mecamylamine hydrochloride [826-39-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	MAP1B RRP1B TSSC4 MAPK8IP3 NBEAL2 GOLGA2	2.49e-04	195	102	6	3525_DN
Drug	Isoetharine mesylate salt [7279-75-6]; Down 200; 12uM; MCF7; HT_HG-U133A	C14orf93 RRP1B SIPA1L3 NBEAL2 ZBTB40 ZNF79	2.49e-04	195	102	6	3451_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	ANK3 SIPA1L3 LUZP1 PDE4DIP ZBTB40 FLCN	2.49e-04	195	102	6	2311_DN
Drug	Lidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A	SIPA1L3 EDA CHRM3 SH2B1 FLCN SEMA6A	2.49e-04	195	102	6	3201_DN
Drug	Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; PC3; HT_HG-U133A	RRP1B PPP1R12B SIPA1L3 SGSM2 FLCN ZNF79	2.49e-04	195	102	6	7400_DN
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	C14orf93 SIPA1L3 NCDN MAP1S NBEAL2 GOLGA2	2.56e-04	196	102	6	5350_UP
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	RRP1B MAP3K6 CYB5B MAP1S SGSM2 AP5Z1	2.56e-04	196	102	6	1794_DN
Drug	Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; PC3; HT_HG-U133A	PPP1R12B SGSM2 CSPG5 ZNF76 ZNF79 GOLGA2	2.56e-04	196	102	6	4570_DN
Drug	Meclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A	ITGA5 NCDN AKAP12 LUZP1 ZNF750 PDE4DIP	2.56e-04	196	102	6	4982_DN
Drug	Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A	ASXL1 SIPA1L3 IRF7 MAP1S PDE4DIP ZBTB40	2.56e-04	196	102	6	7477_DN
Drug	Pimethixene maleate [13187-06-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 PODXL2 ITGA5 SH2B1 AHNAK2	2.56e-04	196	102	6	7426_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A	MAP1B PODXL2 NBEAL2 PDE4DIP ZNF76 ZNF79	2.56e-04	196	102	6	5765_DN
Drug	DNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A	ITGA5 HIVEP3 AP5Z1 ZNF76 ZNF79 GPRIN2	2.56e-04	196	102	6	7513_DN
Drug	Glipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A	APBA2 CHRM3 AKAP12 MAPK8IP3 HIVEP3 ZNF79	2.56e-04	196	102	6	1508_UP
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	APBA2 SH2B1 MAPK8IP3 SGSM2 AP5Z1 FLCN	2.56e-04	196	102	6	4697_DN
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A	C14orf93 APBA2 CHRM3 ZBTB40 ZNF79 HTT	2.56e-04	196	102	6	5007_DN
Drug	Azaperone [1649-18-9]; Down 200; 12.2uM; PC3; HT_HG-U133A	MAP3K6 LUZP1 GSR MAPK8IP3 SGSM2 GOLGA2	2.56e-04	196	102	6	5877_DN
Drug	6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 MAP3K6 NBEAL2 PDCD11 GOLGA2	2.56e-04	196	102	6	4833_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A	C14orf93 SIPA1L3 MAPK8IP3 TOX4 AP5Z1 PDE4DIP	2.56e-04	196	102	6	6942_UP
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	C14orf93 NTRK3 AKAP12 LUZP1 MAPK8IP3 PDE4DIP	2.56e-04	196	102	6	7167_UP
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	C14orf93 PODXL2 ZNF750 PDE4DIP ZNF79 AHNAK2	2.56e-04	196	102	6	5624_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ANK3 MAP3K6 LUZP1 AP5Z1 PDE4DIP FLCN	2.56e-04	196	102	6	1684_DN
Drug	R(+)-verapamil hydrochloride; Up 200; 10uM; MCF7; HG-U133A	RRP1B NTRK3 ZBTB40 GOLGA2 GPRIN2 ZNF646	2.56e-04	196	102	6	164_UP
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	C14orf93 SIPA1L3 MAPK8IP3 HIVEP3 PDE4DIP SEMA6A	2.63e-04	197	102	6	6952_UP
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A	PODXL2 MAPK8IP3 HIVEP3 SGSM2 ZBTB40 ZNF79	2.63e-04	197	102	6	6700_DN
Drug	Carbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A	APBA2 SH2B1 LUZP1 ZNF750 ZNF76 GPRIN2	2.63e-04	197	102	6	3466_UP
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	MDFI SH2B1 RIF1 SGSM2 PDE4DIP ZNF79	2.63e-04	197	102	6	4666_DN
Drug	Trichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A	MAP1B AKAP12 AP5Z1 ZBTB40 AHNAK2 ZNF646	2.63e-04	197	102	6	1675_UP
Drug	Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 MAP1S ZNF79 SEMA6A GPRIN2	2.63e-04	197	102	6	5360_UP
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; HL60; HT_HG-U133A	RRP1B SIPA1L3 PODXL2 HUWE1 ZNF76 GPRIN2	2.63e-04	197	102	6	3056_DN
Drug	Lymecycline [992-21-2]; Down 200; 6.6uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 CHRM3 SH2B1 LUZP1 FLCN	2.63e-04	197	102	6	5994_DN
Drug	Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A	C14orf93 RRP1B ITGA5 CHRM3 LUZP1 HIVEP3	2.63e-04	197	102	6	3195_DN
Drug	Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A	C14orf93 PPP1R12B SH2B1 HIVEP3 SEMA6A GPRIN2	2.63e-04	197	102	6	6453_DN
Drug	Fluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; PC3; HT_HG-U133A	NTRK3 HIVEP3 RIF1 ZNF76 ZNF79 ZNF646	2.63e-04	197	102	6	5741_UP
Drug	Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	INTS1 IRF7 EDA MAPK8IP3 ZNF76 ZNF646	2.63e-04	197	102	6	3388_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; HL60; HT_HG-U133A	SIPA1L3 TOX4 ZBTB40 PLEKHA5 GOLGA2 HTT	2.63e-04	197	102	6	1322_DN
Drug	Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A	RRP1B SH2B1 MAP1S PDE4DIP FLCN ZNF79	2.63e-04	197	102	6	5314_UP
Drug	Eserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; MCF7; HT_HG-U133A	RRP1B PODXL2 RTN1 ZNF76 GPRIN2 ZNF646	2.70e-04	198	102	6	2768_UP
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; HL60; HT_HG-U133A	SIPA1L3 NCDN MAPK8IP3 HIVEP3 NBEAL2 ZNF76	2.70e-04	198	102	6	2549_DN
Drug	Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A	C14orf93 RETREG2 SIPA1L3 INTS1 NCDN PDE4DIP	2.70e-04	198	102	6	3475_DN
Drug	Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; PC3; HT_HG-U133A	C14orf93 RRP1B MAPK8IP3 SGSM2 GOLGA2 GPRIN2	2.70e-04	198	102	6	4595_DN
Drug	Roxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A	TSSC4 SH2B1 LUZP1 PDE4DIP ZNF79 GOLGA2	2.70e-04	198	102	6	3511_DN
Drug	Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; PC3; HT_HG-U133A	MDFI SGSM2 NBEAL2 AP5Z1 ZNF76 GPRIN2	2.70e-04	198	102	6	4569_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; PC3; HT_HG-U133A	RRP1B PPP1R12B MAPK8IP3 HIVEP3 AP5Z1 ZNF76	2.70e-04	198	102	6	4654_DN
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A	NTRK3 INTS1 EDA ZNF750 AP5Z1 ZNF76	2.70e-04	198	102	6	5443_UP
Drug	Prednisone [53-03-2]; Down 200; 11.2uM; HL60; HG-U133A	ASXL1 TSSC4 EDA SGSM2 ZBTB40 FLCN	2.70e-04	198	102	6	1978_DN
Drug	(+/-)-verapamil hydrochloride; Up 200; 10uM; MCF7; HG-U133A	RRP1B NTRK3 SH2B1 ZBTB40 SEMA6A GOLGA2	2.70e-04	198	102	6	161_UP
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	RETREG2 PODXL2 IRF7 MAP3K6 MAP1S PDE4DIP	2.70e-04	198	102	6	983_DN
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A	MAP1B PODXL2 CHRM3 MAPK8IP3 PDE4DIP GPRIN2	2.70e-04	198	102	6	6104_DN
Drug	Tropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A	C14orf93 CHRM3 HIVEP3 MAP1S SGSM2 PDE4DIP	2.70e-04	198	102	6	3569_DN
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	TSSC4 SH2B1 LUZP1 HIVEP3 AP5Z1 ZNF79	2.70e-04	198	102	6	4805_DN
Drug	Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; PC3; HT_HG-U133A	C14orf93 MDFI MAPK8IP3 MAP1S PDE4DIP ZBTB40	2.70e-04	198	102	6	4479_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 CHRM3 AKAP12 PDE4DIP SEMA6A	2.70e-04	198	102	6	6930_UP
Drug	Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	RETREG2 ANK3 MAP3K6 EDA MAPK8IP3 SEMA6A	2.70e-04	198	102	6	3260_UP
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	APBA2 SH2B1 MAPK8IP3 AP5Z1 PDE4DIP ZNF79	2.78e-04	199	102	6	3345_DN
Drug	Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A	NTRK3 MDFI LUZP1 MAPK8IP3 AP5Z1 PDE4DIP	2.78e-04	199	102	6	2625_UP
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	SIPA1L3 PODXL2 SH2B1 ZNF750 PDE4DIP SEMA6A	2.78e-04	199	102	6	5617_DN
Drug	SR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A	SIPA1L3 MDFI SH2B1 MAPK8IP3 AP5Z1 GPRIN2	2.78e-04	199	102	6	6632_DN
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	NTRK3 HUWE1 MAPK8IP3 GJA3 CSPG5 ZNF76	2.78e-04	199	102	6	3615_UP
Drug	Vigabatrin [60643-86-9]; Up 200; 31uM; MCF7; HT_HG-U133A	SIPA1L3 APBA2 EDA NBEAL2 AP5Z1 ZNF79	2.78e-04	199	102	6	5415_UP
Drug	Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	MAP1B SIPA1L3 APBA2 RIF1 AP5Z1 ZBTB40	2.78e-04	199	102	6	7148_DN
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; HL60; HT_HG-U133A	HIVEP3 ZBTB40 FLCN ZNF79 GOLGA2 HTT	2.78e-04	199	102	6	1325_DN
Disease	cataract (implicated_via_orthology)	SIPA1L3 INTS1 GSR GJA3	7.74e-06	38	98	4	DOID:83 (implicated_via_orthology)
Disease	adenoid cystic carcinoma (is_implicated_in)	NTRK3 KMT2C	1.08e-04	5	98	2	DOID:0080202 (is_implicated_in)
Disease	risk-taking behaviour	CCDC170 ZNF536 NTRK3 SH2B1 PHF21A HIVEP3 CYB5B LINC00208 KIAA2012 HTT	2.30e-04	764	98	10	EFO_0008579
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	ANK3 CHRM3	5.89e-04	11	98	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	osteoporosis	CCDC170 HCG22 ZBTB40	1.87e-03	73	98	3	EFO_0003882
Disease	Hematochezia, response to radiation	ERICH1 GSR	2.00e-03	20	98	2	GO_0009314, HP_0002573
Disease	Colorectal Carcinoma	ERICH1 MAP1B EDA NCDN AKAP12 HIVEP3 KMT2C FLCN	2.37e-03	702	98	8	C0009402
Disease	frailty measurement	ANK3 HTT	2.64e-03	23	98	2	EFO_0009885
Disease	odontogenesis	C14orf93 EDA	2.87e-03	24	98	2	GO_0042476
Disease	thalamus volume	AMZ1 CYB5B PLEKHA5	2.88e-03	85	98	3	EFO_0006935

Protein segments in the cluster

Peptide	Gene	Start	Entry
AHLASPSEVGGEPEI	LINC00208	26	Q96KT6
HAEPLTDTGSETPTA	ERICH1	51	Q86X53
GTSVSEPLTPDAGSH	AMZ1	361	Q400G9
SPGTSENHPDTEGET	CSPG5	231	O95196
EDILSSEVSPGHHGP	CRYBG3	2096	Q68DQ2
GSGVEHSTPDTEPGK	AKAP12	786	Q02952
SSSEGIEDETGPPFH	GJA10	246	Q969M2
FSHPPIGTVGLTEDE	GSR	416	P00390
SVATDGPHPSGLTDS	GZF1	166	Q9H116
SPDGTTDDPLGGHTV	CHRM3	51	P20309
SITSASEASPEHGPE	APBA2	241	Q99767
LHSGPEGPGTLDTDD	AP5Z1	251	O43299
EESPDSSPHGEASRG	CLIC6	391	Q96NY7
DGEAKTDPAGLSSPH	ASXL1	451	Q8IXJ9
PHGGEDLTSHPETLT	PCDHGB6	791	Q9Y5F9
SGAEHPDEDPLGSRT	PODXL2	316	Q9NZ53
SSGSDESHVAAAPPD	MMADHC	36	Q9H3L0
SGTHGPADDPLADIS	KMT2C	1421	Q8NEZ4
HPLGGEFSEAPLSTS	KMT2C	2651	Q8NEZ4
PASSIHDETLPGGSE	MAP1B	1081	P46821
SLPAEVGSPHSTEVD	MAP1S	681	Q66K74
DEPDTGDSAHGPTSR	MAGEL2	1231	Q9UJ55
DREGDGEPKSAHTSP	MAPK8IP3	741	Q9UPT6
TSPGHDTSVLPDSVE	NCDN	501	Q9UBB6
HSPAEGASVESSSPG	FLCN	61	Q8NFG4
AGSSPHPSLTEEEDS	INTS1	281	Q8N201
HGITTPSSLDAGPDT	NTRK3	486	Q16288
ASESSASSDGPHPVI	MUC20	211	Q8N307
ASESSASSDGPHPVI	MUC20	306	Q8N307
EPASPEESSGLSLLH	MAP3K6	981	O95382
STSLDDLTPAHGSVP	LRRC36	421	Q1X8D7
SSALTDGGLPADHLP	PDZD7	961	Q9H5P4
LPSPTSTDGDIHEDF	PHF21A	476	Q96BD5
EDSSDPTLGHFLLGP	KIAA2012	586	Q0VF49
SSLPGDLHVTSGPES	LMTK2	616	Q8IWU2
HPEAPGSGEGSEALL	POLG2	56	Q9UHN1
PETTTSGGCHSPEDE	GOLGA6L1	96	Q8N7Z2
SPETTTSGGCHSPED	GOLGA6L22	46	H0YM25
SHPLGSPGSASDLET	NPPB	26	P16860
AALTTGEAAAPESPH	IRF7	251	Q92985
SADVSGSHSPGEPVS	PTPDC1	491	A2A3K4
PVGSLSSEDHDFDPT	MIER3	11	Q7Z3K6
GGAESSSSPHAPESE	OVOL2	66	Q9BRP0
PETTTSGGCHSPEDT	GOLGA2	56	Q08379
PVSEGLEHSDLPDGT	HUWE1	1181	Q7Z6Z7
ADPGTTKHSITADPG	HCG22	211	E2RYF7
EPTPTLTLTGHDEFG	ITGA5	376	P08648
SSIPAAGTEPAADHT	MALRD1	1331	Q5VYJ5
SSLGGLDPDSPITSH	EDA	91	Q92838
HALEETPPSSGAAGS	GBX2	226	P52951
DLPPTHSETESGFSD	NHLH1	11	Q02575
PLDGDGHVSLETVSP	HTT	2081	P42858
VGTSSSESTHPEGPE	E2F6	251	O75461
SSDSHGVDILTPESP	POLQ	1401	O75417
SIPDEDGESRAHSSP	C14orf93	106	Q9H972
IGDIHPSDLKPESGS	CYB5B	96	O43169
EESVTDHAGPPSSEL	ANK3	2481	Q12955
DHAGPPSSELQGSDK	ANK3	2486	Q12955
STHPAEAAPEEGSLE	MDFI	41	Q99750
FSDTTHGSVPSDPLG	LUZP1	511	Q86V48
TSHIALGAASPAPEE	CCDC170	6	Q8IYT3
GSSSPPLAHEAEAGA	GJA3	356	Q9Y6H8
VPPLDLGDTTAHSSS	GPRIN2	196	O60269
SEGTPADTGDLSPGH	PWWP2B	436	Q6NUJ5
SHFTAVPGEPLGDET	KIFC2	166	Q96AC6
GSVPDEHGTDIHPIS	PTCHD3	571	Q3KNS1
SLEHPSGPSDTATDD	MROH2A	1551	A6NES4
PSPLDHEASSAESGD	RTN1	396	Q16799
DGDIHLSPEEPAAST	TAF7L	186	Q5H9L4
SPGAEISPHDLSLES	SH2B1	96	Q9NRF2
TSSTGEESGSEHPPA	RRP1B	451	Q14684
DLPSPGLELSGDHAS	LRRC27	196	Q9C0I9
PLLETLEDPSASHGG	RIF1	11	Q5UIP0
AGPAETHDLVGPELT	NBEAL2	911	Q6ZNJ1
SSPEEPHSDSEGAGS	RETREG2	131	Q8NC44
TPGTPDSSDPSHLLG	PPM1J	201	Q5JR12
HSVEFDSPDSGLPSS	SGSM2	696	O43147
PLPSEGSLAEADHTA	SLTM	211	Q9NWH9
SPSSGEGHLAEPALS	SIPA1L3	451	O60292
PSLGDPVEHLSETSA	KIAA1217	131	Q5T5P2
GEEDHESPSSGRVPA	RNF146	266	Q9NTX7
GSDFGPETSPVLHLD	TANC1	21	Q9C0D5
SGSLPETPEHSSGEE	PPP1R15B	526	Q5SWA1
PGEPGAETEDDHSVT	AHNAK2	26	Q8IVF2
GSDITHEAALAPTAP	SIRPB1	356	O00241
GTEGSEDGPSHPETK	ZNF750	586	Q32MQ0
SHILDDVPEGTSPTT	PDCD11	1066	Q14690
DPEGSDIHFTLDSGP	VWDE	1121	Q8N2E2
LHELSGPAEGASLTP	SRCIN1	871	Q9C0H9
DSPDSTDPLGAVSSH	SEMA6A	611	Q9H2E6
EETSATSGHPAELSP	HIVEP3	286	Q5T1R4
TGEPSPSVEGEHGTE	TSSC4	6	Q9Y5U2
PSGESPHGAEGNLES	ZNF646	711	O15015
EPSGSEISSDSHAPL	ZDBF2	866	Q9HCK1
HPSSPSSSDIGEEAG	ZNF536	716	O15090
LGSGDSEVTEPDHPV	ZBTB2	486	Q8N680
LQPTATPDESEEGHG	ZCWPW2	281	Q504Y3
TEPEPDAVGLDSGHI	TST	191	Q16762
GDDHLSAPTDPQGVD	TRIM64	311	A6NGJ6
GETPTPTESSSHGEG	ZNF629	816	Q9UEG4
TPSTHDKTLGPGAEE	PLEKHA5	476	Q9HAU0
GDDHLSAPTDPQGVD	TRIM64B	311	A6NI03
PPGDSDHGTSDLEKS	ZNF79	136	Q15937
TPSPTSSLHEDGVED	TOX4	176	O94842
IPSPDADLATSGTHT	ZNF76	471	P36508
SEGAGEPHSSPELAA	ZBTB40	151	Q9NUA8
VGTLEGSSPHSVPDE	PDE4DIP	1401	Q5VU43
TEGLEGSPEKHEPSA	PPP1R12B	681	O60237
DGDTLGFPPLTTEHS	NECTIN4	296	Q96NY8