Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A8 SLC4A3 SLC26A8 SLC4A5

9.31e-06321805GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC4A8 SLC4A3 SLC26A8 SLC4A5

9.31e-06321805GO:0005452
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A5

1.41e-0561803GO:0008510
GeneOntologyMolecularFunctioncalcium ion binding

UNC13B CABP5 DSG2 CDHR2 CETN2 CAPN2 NUCB1 BCAN RYR1 RYR3 BMP1 SLC8A1 CDH22 TCHH SUSD1 RASEF EFCC1 PLA2G4F CAPS2 CDH5

1.47e-0574918020GO:0005509
GeneOntologyMolecularFunctionankyrin binding

SPTB OBSCN SLC8A1 PLEC

4.95e-05231804GO:0030506
GeneOntologyMolecularFunctioncytoskeletal protein binding

PRICKLE4 SYNPO2 CTTNBP2 CALD1 KIF26B MYH7B CETN2 SPTB CAPN2 CEP290 OBSCN FHOD3 ADCY8 TRAK1 CEP350 SLC8A1 SYNE3 FEZ1 MYH14 NISCH COBL PLEC PDLIM2 VBP1

5.34e-05109918024GO:0008092
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A5

1.93e-04131803GO:0140410
GeneOntologyMolecularFunctionmolecular adaptor activity

DCAF1 NCOA2 LDLRAP1 SYNPO2 RAPSN RETREG2 IRF4 BTAF1 SNAP47 DDB1 LDB2 IFNAR2 FEM1B AP4E1 TCHH SYNE3 AP2B1 MYH14 HELZ2 TCF25 TAB1 PIH1D1 MAP2K2 AIM2 MED13 PCNT

2.12e-04135618026GO:0060090
GeneOntologyMolecularFunctioncalmodulin binding

UNC13B CALD1 OBSCN ADCY8 RYR1 RYR3 SLC8A1 MYH14 PCNT

2.48e-042301809GO:0005516
GeneOntologyMolecularFunctionmuscle alpha-actinin binding

PRICKLE4 SYNPO2 PDLIM2

3.03e-04151803GO:0051371
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

DCAF1 NCOA2 LDLRAP1 SYNPO2 RAPSN RETREG2 IRF4 BTAF1 SNAP47 DDB1 LDB2 IFNAR2 FEM1B AP4E1 TCHH SYNE3 AP2B1 HELZ2 TCF25 PIH1D1 MAP2K2 AIM2 MED13

3.17e-04116018023GO:0030674
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

4.79e-0441802GO:0005219
GeneOntologyMolecularFunctioncell adhesion molecule binding

RANGAP1 CALD1 DSG2 CDHR2 OBSCN ITGA10 LAMA5 ITGA7 TGFBI CDH22 NISCH PLEC CDH5 PHLDB2

1.10e-0359918014GO:0050839
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

1.18e-0361802GO:0048763
GeneOntologyMolecularFunctionactin binding

PRICKLE4 SYNPO2 CALD1 MYH7B SPTB FHOD3 ADCY8 SYNE3 MYH14 COBL PLEC PDLIM2

1.39e-0347918012GO:0003779
GeneOntologyMolecularFunctioncargo adaptor activity

LDLRAP1 AP4E1 AP2B1

1.43e-03251803GO:0140312
GeneOntologyBiologicalProcessorganelle assembly

KRT8 SYNPO2 CETN2 IFT172 CEP290 OBSCN LAMA5 RNF213 FHOD3 BBS9 DDB1 CEP350 LRGUK AP1B1 FEZ1 NISCH CEP250 RAB3IP PAN2 TNKS PLEC LZTS2 DNMBP PCNT CCDC40

1.77e-05113817925GO:0070925
GeneOntologyBiologicalProcessbicarbonate transport

SLC4A7 SLC4A8 SLC4A3 SLC26A8 SLC4A5

1.85e-05381795GO:0015701
GeneOntologyCellularComponentZ disc

PRICKLE4 KRT8 SYNPO2 OBSCN FHOD3 RYR1 RYR3 SLC8A1 RTL1 PYGM PLEC PDLIM2

7.16e-0915117912GO:0030018
GeneOntologyCellularComponentI band

PRICKLE4 KRT8 SYNPO2 OBSCN FHOD3 RYR1 RYR3 SLC8A1 RTL1 PYGM PLEC PDLIM2

2.08e-0816617912GO:0031674
GeneOntologyCellularComponentmyofibril

PRICKLE4 KRT8 SYNPO2 CALD1 MYH7B OBSCN FHOD3 RYR1 RYR3 SLC8A1 RTL1 PYGM PLEC PDLIM2

1.04e-0727317914GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

PRICKLE4 KRT8 SYNPO2 CALD1 MYH7B OBSCN FHOD3 RYR1 RYR3 SLC8A1 RTL1 PYGM PLEC PDLIM2

2.18e-0729017914GO:0043292
GeneOntologyCellularComponentsarcomere

PRICKLE4 KRT8 SYNPO2 OBSCN FHOD3 RYR1 RYR3 SLC8A1 RTL1 PYGM PLEC PDLIM2

1.68e-0624917912GO:0030017
GeneOntologyCellularComponentcell cortex

UNC13B CTTNBP2 CALD1 SPTB CAPN2 RYR1 TRAK1 RAPGEF3 CLTA COBL MAP2K2 PDLIM2 PHLDB2

1.97e-0537117913GO:0005938
GeneOntologyCellularComponentcortical actin cytoskeleton

CALD1 SPTB CAPN2 RAPGEF3 COBL PDLIM2

1.49e-04931796GO:0030864
GeneOntologyCellularComponentsupramolecular fiber

LDLRAP1 NES PRICKLE4 KRT8 SYNPO2 CALD1 KIF26B MYH7B OBSCN FHOD3 RYR1 RYR3 SLC8A1 FEZ1 MYH14 RTL1 COBL PYGM PLEC LZTS2 MAP2K2 PDLIM2 PCNT

1.92e-04117917923GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

LDLRAP1 NES PRICKLE4 KRT8 SYNPO2 CALD1 KIF26B MYH7B OBSCN FHOD3 RYR1 RYR3 SLC8A1 FEZ1 MYH14 RTL1 COBL PYGM PLEC LZTS2 MAP2K2 PDLIM2 PCNT

2.11e-04118717923GO:0099081
GeneOntologyCellularComponentnuclear membrane

IPO5 RANGAP1 INTS1 RIF1 UTP18 SYNE3 RNF6 ANKRD17 ITPRIP TNKS CDH5

2.20e-0434917911GO:0031965
GeneOntologyCellularComponentsarcolemma

TRIM72 KRT8 OBSCN ITGA7 RYR1 RYR3 SLC8A1 PLEC

2.39e-041901798GO:0042383
GeneOntologyCellularComponentanchoring junction

PRICKLE4 RRAS2 KRT8 SYNPO2 DSG2 RPLP2 CDHR2 CAPN2 OBSCN ITGA7 LAP3 SLC8A1 CDH22 SKAP1 PLEC DNMBP MAP2K2 CDH5 PDLIM2 PHLDB2

2.75e-0497617920GO:0070161
GeneOntologyCellularComponenttrans-Golgi network

NUCB1 CPD LAP3 TGFBI AP4E1 VPS52 ATP8A1 AP1B1 RAB3IP CLTA

3.19e-0430617910GO:0005802
GeneOntologyCellularComponentFAR/SIN/STRIPAK complex

CTTNBP2 STRIP2 STK25

3.84e-04171793GO:0090443
GeneOntologyCellularComponentdendrite

NCOA2 RANGAP1 CTTNBP2 SLC4A8 CALD1 CAPN2 BCAN SNAP47 ADCY8 TRAK1 DIP2A SLC8A1 FEZ1 RAB3IP XRN1 COBL PLEC HNRNPR

4.26e-0485817918GO:0030425
GeneOntologyCellularComponentdendritic tree

NCOA2 RANGAP1 CTTNBP2 SLC4A8 CALD1 CAPN2 BCAN SNAP47 ADCY8 TRAK1 DIP2A SLC8A1 FEZ1 RAB3IP XRN1 COBL PLEC HNRNPR

4.38e-0486017918GO:0097447
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

VPS33A AP4E1 AP1B1 AP2B1

7.54e-04481794GO:0030119
GeneOntologyCellularComponentcortical cytoskeleton

CALD1 SPTB CAPN2 RAPGEF3 COBL PDLIM2

8.64e-041291796GO:0030863
GeneOntologyCellularComponentnuclear envelope

IPO5 RANGAP1 CETN2 INTS1 CC2D1B RIF1 UTP18 SYNE3 RNF6 ANKRD17 ITPRIP TNKS CDH5

1.11e-0356017913GO:0005635
GeneOntologyCellularComponentmyosin filament

MYH7B OBSCN MYH14

1.24e-03251793GO:0032982
GeneOntologyCellularComponentclathrin coat

VPS33A AP1B1 AP2B1 CLTA

1.35e-03561794GO:0030118
GeneOntologyCellularComponentactin cytoskeleton

PRICKLE4 SYNPO2 CTTNBP2 CALD1 MYH7B SPTB CAPN2 FHOD3 ADCY8 MYH14 RAPGEF3 COBL PDLIM2

1.43e-0357617913GO:0015629
GeneOntologyCellularComponentGolgi apparatus subcompartment

NUCB1 CPD LAP3 TGFBI AP4E1 VPS52 ATP8A1 AP1B1 RAB3IP CLTA DNMBP

1.57e-0344317911GO:0098791
GeneOntologyCellularComponentbasal part of cell

LDLRAP1 SLC4A7 SLC4A8 ADCY8 SLC8A1 SLC16A5 RAPGEF3 PLEC SLC4A5 PHLDB2

1.61e-0337817910GO:0045178
GeneOntologyCellularComponentpericentriolar material

BBS9 TNKS PCNT

1.73e-03281793GO:0000242
GeneOntologyCellularComponentcoated membrane

VPS33A AP4E1 AP1B1 AP2B1 CLTA

2.20e-031061795GO:0048475
GeneOntologyCellularComponentmembrane coat

VPS33A AP4E1 AP1B1 AP2B1 CLTA

2.20e-031061795GO:0030117
GeneOntologyCellularComponentcontractile actin filament bundle

PRICKLE4 SYNPO2 CALD1 MYH14 PDLIM2

2.29e-031071795GO:0097517
GeneOntologyCellularComponentstress fiber

PRICKLE4 SYNPO2 CALD1 MYH14 PDLIM2

2.29e-031071795GO:0001725
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

2.52e-0391792GO:0030314
GeneOntologyCellularComponentclathrin complex

VPS33A CLTA

2.52e-0391792GO:0071439
GeneOntologyCellularComponenttrans-Golgi network membrane

AP4E1 VPS52 AP1B1 RAB3IP CLTA

2.79e-031121795GO:0032588
GeneOntologyCellularComponentactomyosin

PRICKLE4 SYNPO2 CALD1 MYH14 PDLIM2

3.37e-031171795GO:0042641
GeneOntologyCellularComponentactin filament bundle

PRICKLE4 SYNPO2 CALD1 MYH14 PDLIM2

3.49e-031181795GO:0032432
GeneOntologyCellularComponentbasal plasma membrane

LDLRAP1 SLC4A7 SLC4A8 ADCY8 SLC8A1 SLC16A5 RAPGEF3 PLEC SLC4A5

3.54e-033541799GO:0009925
DomainANION_EXCHANGER_2

SLC4A7 SLC4A8 SLC4A3 SLC4A5

2.73e-0771784PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A8 SLC4A3 SLC4A5

2.73e-0771784PS00219
Domain-

SLC4A7 SLC4A8 SLC4A3 SLC4A5

9.68e-07917843.40.1100.10
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A8 SLC4A3 SLC4A5

9.68e-0791784IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A8 SLC4A3 SLC4A5

9.68e-0791784PF07565
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.60e-06101784IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.60e-06101784IPR003020
DomainHCO3_cotransp

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.60e-06101784PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.60e-06101784IPR011531
DomainCoatomer/calthrin_app_sub_C

AP4E1 AP1B1 AP2B1

4.60e-0581783IPR009028
DomainEF_hand_dom

CABP5 CETN2 CAPN2 NUCB1 RYR1 RYR3 TCHH RASEF EFCC1 CAPS2

7.95e-0523217810IPR002048
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

9.03e-0521782IPR013037
Domain-

AP1B1 AP2B1

9.03e-05217822.60.40.1150
DomainARM-type_fold

DOCK1 DCAF1 IPO5 IFT172 INTS1 FHOD3 BTAF1 RYR3 AP4E1 RIF1 AP1B1 AP2B1

1.03e-0433917812IPR016024
DomainRyanodine_rcpt

RYR1 RYR3

2.69e-0431782IPR003032
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

2.69e-0431782IPR016342
DomainRyanrecept_TM4-6

RYR1 RYR3

2.69e-0431782IPR009460
DomainRyR

RYR1 RYR3

2.69e-0431782PF02026
DomainB2-adapt-app_C

AP1B1 AP2B1

2.69e-0431782PF09066
DomainRR_TM4-6

RYR1 RYR3

2.69e-0431782PF06459
DomainRyan_recept

RYR1 RYR3

2.69e-0431782IPR013333
DomainClathrin/coatomer_adapt-like_N

AP4E1 AP1B1 AP2B1

3.56e-04151783IPR002553
DomainAdaptin_N

AP4E1 AP1B1 AP2B1

3.56e-04151783PF01602
DomainEF_HAND_2

CABP5 CETN2 CAPN2 NUCB1 RYR3 TCHH RASEF EFCC1 CAPS2

3.83e-042311789PS50222
DomainAAA

ABCA12 ABCA13 RNF213 MCM4 BCS1L DHX15 HELZ2

4.66e-041441787SM00382
DomainAAA+_ATPase

ABCA12 ABCA13 RNF213 MCM4 BCS1L DHX15 HELZ2

4.66e-041441787IPR003593
DomainB2-adapt-app_C

AP1B1 AP2B1

5.35e-0441782SM01020
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

5.35e-0441782IPR015151
DomainEF-hand_1

CABP5 CETN2 CAPN2 NUCB1 RYR3 TCHH CAPS2

6.44e-041521787PF00036
DomainEF_HAND_1

CABP5 CETN2 CAPN2 NUCB1 TCHH RASEF EFCC1 CAPS2

7.73e-042041788PS00018
DomainAP_beta

AP1B1 AP2B1

8.86e-0451782IPR026739
DomainNa/HCO3_transpt

SLC4A8 SLC4A5

8.86e-0451782IPR003024
DomainAnion_exchange

SLC4A7 SLC4A3

8.86e-0451782IPR001717
Domain-

CABP5 CETN2 CAPN2 NUCB1 RYR1 RYR3 TCHH RASEF CAPS2

9.18e-0426117891.10.238.10
DomainARM-like

DCAF1 IPO5 RANGAP1 FHOD3 BTAF1 AP4E1 RIF1 AP1B1 AP2B1

1.16e-032701789IPR011989
DomainRIH_assoc-dom

RYR1 RYR3

1.32e-0361782IPR013662
DomainIns145_P3_rec

RYR1 RYR3

1.32e-0361782PF08709
DomainRIH_assoc

RYR1 RYR3

1.32e-0361782PF08454
DomainRIH_dom

RYR1 RYR3

1.32e-0361782IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3

1.32e-0361782IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3

1.32e-0361782IPR015925
Domain-

RYR1 RYR3

1.32e-03617821.25.10.30
DomainRYDR_ITPR

RYR1 RYR3

1.32e-0361782PF01365
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

1.32e-0361782IPR012295
Domain-

AP1B1 AP2B1

1.32e-03617823.30.310.10
DomainCadherin_C

DSG2 CDH22 CDH5

1.68e-03251783PF01049
DomainCadherin_cytoplasmic-dom

DSG2 CDH22 CDH5

1.68e-03251783IPR000233
DomainEF-hand-dom_pair

CABP5 CETN2 CAPN2 NUCB1 RYR1 RYR3 TCHH RASEF CAPS2

1.77e-032871789IPR011992
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.52e-06101334M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.52e-06101334MM15073
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 NES RANGAP1 DDX31 RPLP2 INTS1 MCM4 RBM28 DDB1 DHX15 RIF1 UTP18 AP1B1 AP2B1 MYH14 SUPT6H HELZ2 XRN1 SLTM ANKRD17 PLEC PCNT

5.58e-126531822222586326
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

UNC13B DCAF1 IPO5 TSR2 KRT8 RANGAP1 GALK1 CTTNBP2 CETN2 MCM4 STRIP2 FEM1B POLR1F UTP18 AP2B1 SUPT6H AFP OTUD6B CLTA PAN2 ANKRD17 TNKS PLEC KLHL8 VBP1 STK25

2.11e-1110051822619615732
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

IPO5 NES RRAS2 RANGAP1 CALD1 DSG2 RPLP2 CEP290 INTS1 MCM4 BTAF1 RBM28 DDB1 CEP350 DHX15 RIF1 AARS2 MYH14 SUPT6H CLTA SLTM PLEC PHLDB2 HNRNPR PCNT

1.79e-1010241822524711643
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B SEMA6C PALD1 INTS1 OBSCN LAMA5 BTAF1 SMG5 REV3L RYR1 PLEKHH3 TRAK1 DIP2A SYNE3 SLC16A5 NISCH HELZ2 C19orf44 COBL PCNX1 ZNF579 PLEC DNMBP MED13 PCNT

8.56e-1011051822535748872
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

KRT8 RANGAP1 CALD1 DSG2 CEP290 CPD DDB1 CEP350 AP4E1 VPS52 PROSER3 CEP250 XRN1 COBL RASEF TAB1 PLEC PIH1D1 DNMBP VBP1 PCNT

4.97e-098531822128718761
Pubmed

Defining the membrane proteome of NK cells.

IPO5 GALK1 RPLP2 CEP290 NUCB1 INTS1 RNF213 MCM4 IRF4 CPD CEP350 SYNE3 ATP8A1 AP2B1 MYH14 NISCH CLTA HELZ2 XRN1 ANKRD17 ITPRIP MAP2K3 MED13 PCNT

1.23e-0811681822419946888
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 NES RRAS2 RANGAP1 GALK1 RPLP2 CAPN2 MCM4 RBM28 DDB1 DHX15 POLR1F RIF1 UTP18 ADPRS AP2B1 MYH14 XRN1 SLTM ANKIB1 ANKRD17 PLEC MAP2K3 PHLDB2 HNRNPR

4.70e-0813531822529467282
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

DCAF1 NES KRT8 CALD1 DSG2 SPTB BTAF1 AARS2 AP1B1 ZNF579 PLEC PCNT STK25

6.53e-083601821333111431
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B NCOA2 IPO5 LDLRAP1 IFT172 SPTB CEP290 NUCB1 SMG5 REV3L PNISR SLC4A3 LDB2 RYR3 CEP350 DIP2A AP2B1 FEZ1 MYH14 NISCH TNKS PLEC MED13 PCNT

7.36e-0812851822435914814
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 IPO5 LDLRAP1 RANGAP1 VPS33A INTS1 BTAF1 DDB1 RIF1 GSDME AP1B1 PLEC MAP2K2 MAP2K3 HNRNPR PCNT

8.40e-085821821620467437
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

DDX31 HECW1 MYH7B LAMA5 RNF213 DDB1 DHX15 RIF1 MYH14 HELZ2 HNRNPR

9.63e-082501821133536335
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

IPO5 NES KRT8 RANGAP1 GALK1 CALD1 RPLP2 CETN2 MCM4 DDB1 LAP3 DHX15 AP1B1 AP2B1 NISCH CLTA PEX19 ANKRD17 TAB1 PLEC VBP1 HNRNPR

1.77e-0711491822235446349
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

CTTNBP2 CAPN2 VPS33A STRIP2 SUPT6H XRN1 PAN2 ANKRD17 PIH1D1 PCNT

1.97e-072121821033853758
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

PRICKLE4 ABCA12 CAPN2 OBSCN LAMA5 RNF213 BCS1L RYR1 PLEC STK25

2.15e-072141821022199357
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DCAF1 IPO5 RRAS2 GALK1 DSG2 IFT172 CAPN2 MCM4 CPD RBM28 DDB1 AP1B1 AP2B1 PEX19 XRN1 ANKRD17 TNKS TAB1 LZTS2 VBP1

2.24e-079741822028675297
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

TRIM72 INTS1 BTAF1 DDB1 DHX15 RIF1 VPS52 SUPT6H TAB1 PLEC MED13

2.25e-072721821131010829
Pubmed

A human MAP kinase interactome.

DOCK1 KRT8 SYNPO2 KIF26B CEP290 PNISR CEP350 RIF1 AP2B1 CEP250 ANKRD17 COBL PLEC MAP2K2

3.19e-074861821420936779
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

IPO5 CTTNBP2 SPTB OBSCN RYR1 DHX15 GSDME MYH14 SUPT6H PYGM TNKS PLEC MED13 HNRNPR

4.17e-074971821423414517
Pubmed

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.

SLC4A7 SLC4A8 SLC4A5

5.62e-074182317715183
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

RANGAP1 CALD1 RPLP2 VPS33A HKDC1 MCM4 RBM28 AP1B1 AP2B1 MYH14 SUPT6H CEP250 CLTA ANKRD17 PLEC MAP2K3 VBP1 PCNT

5.72e-078471821835235311
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

IPO5 RANGAP1 CALD1 DSG2 RPLP2 MCM4 SSR1 RBM28 DDB1 DHX15 UTP18 AP2B1 MYH14 CLTA SLTM TCF25 PLEC MAP2K3 HNRNPR

6.68e-079491821936574265
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

UNC13B NCOA2 SLC4A7 SLC4A8 ZNF235 DHX15 AP1B1 NISCH TLR2 PCNX1 DNMBP CDH5

6.82e-073711821215747579
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

NES KRT8 RANGAP1 SLC4A7 DSG2 KIF26B XRN1 ANKRD17 PLEC PIH1D1

1.11e-062561821033397691
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

CETN2 MCM4 FEZ1 CEP250 TNKS LZTS2 PCNT

1.16e-06102182720508983
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

IPO5 GALK1 RPLP2 NUCB1 LAMA5 MCM4 RBM28 LAP3 DHX15 AP2B1 MYH14 CLTA HELZ2 SLTM PLEC MAP2K2 HNRNPR

1.26e-068031821736517590
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

IPO5 RANGAP1 DSG2 IFT172 MCM4 DDB1 DHX15 RIF1 AARS2 AP1B1 AP2B1 SUPT6H PLEC MAP2K2 HNRNPR

1.53e-066381821533239621
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

IPO5 RANGAP1 CAPN2 MCM4 CPD BCS1L DDB1 VPS52 UTP18 AARS2 AP1B1 AP2B1 SUPT6H TCF25

1.70e-065601821435241646
Pubmed

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

CETN2 CEP290 CEP250 PCNT

2.64e-0619182424421332
Pubmed

CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels.

DCAF1 DDB1 CEP350

2.79e-066182334259627
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DCAF1 IPO5 RRAS2 RANGAP1 RETREG2 CALD1 DSG2 CETN2 LCN1 DDB1 CRY2 CEP350 DHX15 PHF20L1 AP2B1 ITPRIP PYGM VBP1 HNRNPR STK25

3.08e-0611551822020360068
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES KRT8 SLC4A7 DSG2 RPLP2 KIF26B TRAK1 CEP350 POLR1F XRN1 ANKRD17 COBL TAB1 PLEC DNMBP MAP2K2 PHLDB2

3.21e-068611821736931259
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 RANGAP1 SLC4A7 DDX31 DSG2 RPLP2 NUCB1 CPD SSR1 RBM28 SNAP47 BCS1L DDB1 DIP2A UTP18 SYNE3 SUPT6H NISCH CLTA PEX19 LZTS2 PIH1D1 PCNT

3.54e-0614871822333957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 NCOA2 CPAMD8 CALD1 SPTB OBSCN TMEM63C RNF213 CPD BTAF1 FOXN3 MYH14 SUPT6H RAB3IP ANKIB1 ANKRD17 COBL RASEF LZTS2 MAP2K2 MAP2K3 SLC4A5 PCNT

3.62e-0614891822328611215
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

CAPN2 RYR1 RYR3

4.86e-067182320962236
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

DCAF1 DSG2 INTS1 DDB1 CEP350 VPS52 XRN1 ANKRD17 MAP2K3

5.73e-06242182934011540
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

NCOA2 PALD1 CTTNBP2 CALD1 DSG2 RPLP2 SPTB OBSCN CC2D1B IRGQ AARS2 FEZ1 RAPGEF3 CLTA MAP3K15 ZNF579 KLHL8 LZTS2 TVP23A MED13

6.52e-0612151822015146197
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANGAP1 CALD1 CETN2 ESRRA SMG5 CEP350 DHX15 POLR1F MYH14 XRN1 ANKRD17 PLEC DNMBP MAP2K3 HNRNPR

7.05e-067241821536232890
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

DOCK1 IPO5 RANGAP1 CAPN2 INTS1 DDB1 DHX15 SUPT6H PIH1D1 MAP2K2 HNRNPR

7.40e-063901821117643375
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

KRT8 MCM4 RBM28 SLTM ANKRD17 PLEC

8.18e-0690182635654790
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

RANGAP1 RPLP2 ABCA13 INTS1 SSR1 LCN1 DDB1 DHX15 RIF1 MYH14 SLTM PYGM PLEC HNRNPR

9.66e-066521821431180492
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PNISR TRAK1 CRY2 CEP350 AP4E1 VPS52 UTP18 AP1B1 AP2B1 PEX19 XRN1 TCF25 C19orf44 TNKS TAB1 LZTS2 PIH1D1 MAP2K2

9.68e-0610381821826673895
Pubmed

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

RRAS2 KRT8 CALD1 DSG2 RPLP2 MYH14 CLTA PAN2 PLEC LZTS2

9.92e-063281821023398456
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B DCAF1 PALD1 IFT172 STRIP2 TRAK1 FEM1B NISCH TCF25 COBL PCNT

1.10e-054071821112693553
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

CTTNBP2 CALD1 RPLP2 OBSCN SSR1 DHX15 AP2B1 TAB1 PLEC HNRNPR

1.13e-053331821032665550
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 DCAF1 IPO5 BTAF1 MYH14 XRN1 ANKRD17 PLEC

1.21e-05202182833005030
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOA2 RRAS2 RANGAP1 SLC4A7 MCM4 BTAF1 SMG5 FOXN3 REV3L LDB2 RIF1 AARS2 PHF20L1 NISCH ANKRD17 MAP2K3

1.26e-058571821625609649
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IPO5 PALD1 SLC4A7 RNF213 CPD RBM28 SNAP47 BCS1L DDB1 TRAK1 DIP2A VPS52 UTP18 AARS2 NISCH PEX19 TAB1 PIH1D1 MIEF2 VBP1 HNRNPR PCNT

1.29e-0514961822232877691
Pubmed

Genetic link between renal birth defects and congenital heart disease.

CEP290 LAMA5 AP1B1 AP2B1

1.35e-0528182427002738
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DOCK1 CEP290 LAMA5 AP1B1 AP2B1 TAB1

1.50e-05100182625807483
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RANGAP1 ESRRA MCM4 BTAF1 PNISR RIF1 UTP18 HELZ2 ANKRD17 ZNF579 PLEC DNMBP MAP2K2 MED13 PHLDB2

1.55e-057741821515302935
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DCAF1 NES DDX31 RPLP2 CETN2 MCM4 RBM28 DDB1 LAP3 DHX15 POLR1F RIF1 UTP18 SUPT6H SLTM PLEC HNRNPR

1.93e-059891821736424410
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DOCK1 GALK1 DSG2 CPD SNAP47 AP4E1 VPS52 AP1B1 COBL

2.11e-05285182934369648
Pubmed

Network organization of the human autophagy system.

DOCK1 DCAF1 IPO5 TSR2 VPS33A IRGQ DDB1 LAP3 RIF1 CLTA MAP3K15

2.13e-054371821120562859
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DOCK1 IPO5 PALD1 RANGAP1 CALD1 DSG2 MCM4 CC2D1B CPD DDB1 DHX15 XRN1 TCF25 ANKRD17

2.40e-057081821439231216
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA6C RANGAP1 LAMA5 SMG5 SUPT6H ANKIB1 PAN2 ANKRD17 PCNX1 LZTS2 DNMBP MED13

2.49e-055291821214621295
Pubmed

The DNA sequence and analysis of human chromosome 14.

TMEM63C FOXN3 SYNE3 RTL1 TMEM179 PCNX1

2.72e-05111182612508121
Pubmed

Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis.

SYNE3 PLEC

2.72e-052182223761073
Pubmed

Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest.

DCAF1 DDB1

2.72e-052182224558487
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.72e-05218229489997
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

2.72e-052182212640042
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

2.72e-052182214592949
Pubmed

The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection.

DCAF1 DDB1

2.72e-052182219264781
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

2.72e-05218229799464
Pubmed

Epac1 regulates integrity of endothelial cell junctions through VE-cadherin.

RAPGEF3 CDH5

2.72e-052182216115630
Pubmed

ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells.

LDLRAP1 AP1B1

2.72e-052182221444685
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

2.72e-052182217118445
Pubmed

AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity.

IRF4 AIM2

2.72e-052182237867943
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

2.72e-052182211500519
Pubmed

A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm.

AFP ANKRD17

2.72e-052182211165478
Pubmed

Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx.

DCAF1 DDB1

2.72e-052182225499532
Pubmed

Autophagosome-lysosome fusion is facilitated by plectin-stabilized actin and keratin 8 during macroautophagic process.

KRT8 PLEC

2.72e-052182235080691
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

2.72e-052182212565913
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.72e-05218229192302
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

2.72e-05218227556644
Pubmed

Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest.

DCAF1 DDB1

2.72e-052182224912982
Pubmed

Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis.

OGN BMP1

2.72e-052182215292192
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

2.72e-052182215894801
Pubmed

Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy.

MYH7B ITGA7

2.72e-052182223800289
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

2.72e-05218229817784
Pubmed

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system.

DCAF1 DDB1

2.72e-052182217559673
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

IPO5 RANGAP1 SLC4A7 DSG2 CPD SSR1 DHX15 NISCH XRN1 ANKRD17 VBP1

2.72e-054491821131732153
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

SLC4A7 DHX15 FEM1B RIF1 PHF20L1 ANKIB1 HNRNPR

2.77e-05165182716107646
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

KRT8 RETREG2 SSR1 ZNF235 BCS1L LAP3 DHX15 FEZ1 CLTA TCF25 C19orf44 TAB1 ZNF579 PIH1D1 MAP2K3 VBP1 HNRNPR STK25

2.78e-0511241821821900206
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR3 SLC8A1

3.00e-0512182319095005
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

IPO5 RRAS2 RANGAP1 RPLP2 MCM4 DDB1 DHX15 RNF6 AP2B1 MYH14 CLTA XRN1 ANKRD17 LZTS2 MAP2K2 MAP2K3 MED13 PHLDB2 HNRNPR

3.24e-0512471821927684187
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PALD1 NES SLC4A7 CEP290 RNF213 RBM28 SNAP47 DDB1 STRIP2 CEP350 VPS52 PROSER3 PEX19 XRN1

3.50e-057331821434672954
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

DCAF1 RPLP2 CEP290 DDB1 CEP350 DHX15 SUPT6H CEP250 ANKIB1 ANKRD17 LZTS2 PHLDB2 HNRNPR

3.53e-056391821323443559
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

DOCK1 IPO5 PALD1 CTTNBP2 RPLP2 DDB1 MYH14 PLEC

3.59e-05235182830258100
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CETN2 CEP290 PCNT

3.88e-0513182317920017
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

HECW1 NUCB1 LAMA5 DDB1 LAP3 CLTA PEX19 ANKIB1 TCF25 COBL LZTS2 HNRNPR

4.32e-055601821221653829
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

IPO5 MCM4 BTAF1 RBM28 DDB1 DHX15 RIF1 UTP18 AP1B1 AP2B1 SUPT6H SLTM HNRNPR

4.41e-056531821333742100
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

RANGAP1 CALD1 RPLP2 DHX15 POLR1F AP2B1 CLTA TAB1 HNRNPR

4.83e-05317182917620599
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 NES RANGAP1 CTTNBP2 SLC4A8 HECW1 DDB1 LDB2 AP1B1 AP2B1 NISCH RAB3IP ANKRD17 TNKS PHLDB2 PCNT

5.13e-059631821628671696
Pubmed

A "double adaptor" method for improved shotgun library construction.

SEMA6C CPD BCS1L CEP350 RIF1 CDH22 GSDME UTP18 ATP8A1 RAPGEF3 SUPT6H TNKS

5.48e-05574182128619474
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

KRT8 CALD1 RPLP2 CAPN2 LAMA5 DDB1 TGFBI AP2B1 MYH14 PLEC PHLDB2

5.77e-054881821131324722
Pubmed

Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.

DSG2 OBSCN BTAF1 DHX15 NISCH HNRNPR

6.88e-05131182628031328
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT8 RANGAP1 CALD1 MYH7B CETN2 NUCB1 HKDC1 CC2D1B PNISR SLC4A3 UTP18 PHF20L1 AP2B1 SUSD1 MYH14 XRN1 PLEC MED13 HNRNPR PCNT

7.35e-0514421822035575683
Pubmed

Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

SEMA6C NES SEMA3D

7.51e-0516182322632726
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CALD1 DSG2 KIF26B CEP290 INTS1 PLEKHH3 CEP350 SYNE3 AARS2 ITPRIP ZNF579 LZTS2 STK25

7.57e-056891821336543142
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

8.14e-053182218403125
InteractionSIRT7 interactions

DCAF1 IPO5 NES RANGAP1 DDX31 RPLP2 INTS1 MCM4 RBM28 DDB1 DHX15 RIF1 UTP18 AP1B1 AP2B1 MYH14 SUPT6H HELZ2 XRN1 SLTM ANKRD17 PLEC PCNT

2.46e-0774418123int:SIRT7
InteractionCEP78 interactions

DCAF1 IPO5 VPS33A DDB1 TRAK1 CEP350 CEP250 CDH5

2.45e-06961818int:CEP78
InteractionOFD1 interactions

IPO5 KRT8 CAPN2 CEP290 IRF4 CEP350 SYNE3 AP2B1 XRN1 PAN2 LZTS2 PIH1D1 PHLDB2 PCNT

3.22e-0634718114int:OFD1
InteractionN4BP2 interactions

KRT8 SYNE3 AP2B1 CEP250 ANKRD17 PLEC LZTS2

1.56e-05891817int:N4BP2
InteractionTOP3B interactions

UNC13B IPO5 SEMA6C PALD1 SPTB INTS1 OBSCN LAMA5 BTAF1 SMG5 REV3L RYR1 PLEKHH3 TRAK1 DIP2A SYNE3 SLC16A5 NISCH CLTA HELZ2 XRN1 C19orf44 ANKRD17 COBL PCNX1 ZNF579 PLEC DNMBP MED13 PCNT

1.92e-05147018130int:TOP3B
InteractionCCDC18 interactions

KRT8 CEP290 SYNE3 AP2B1 CEP250 PCNT

3.33e-05681816int:CCDC18
InteractionTNRC6C interactions

KRT8 SYNE3 AP2B1 CLTA PAN2 ANKRD17 TAB1 LZTS2

3.56e-051381818int:TNRC6C
InteractionCEP152 interactions

KRT8 MCM4 SMG5 CEP350 SYNE3 AP2B1 XRN1 LZTS2 PCNT

3.57e-051791819int:CEP152
InteractionTNRC6A interactions

NES KRT8 SMG5 SYNE3 AP2B1 CEP250 CLTA PAN2 ANKRD17 LZTS2 MED13

4.78e-0528018111int:TNRC6A
InteractionTNRC6B interactions

KRT8 SMG5 SYNE3 AP2B1 CLTA XRN1 PAN2 ANKRD17 LZTS2 PIH1D1 DNMBP

5.09e-0528218111int:TNRC6B
InteractionMTDH interactions

PRICKLE4 ABCA12 ESRRA CAPN2 OBSCN LAMA5 RNF213 SSR1 RBM28 BCS1L RYR1 AP2B1 OTUD6B PLEC STK25

5.37e-0550518115int:MTDH
InteractionCEP250 interactions

DCAF1 RPLP2 DDB1 CEP350 DHX15 SUPT6H CEP250 ANKIB1 LZTS2 PHLDB2 HNRNPR

5.96e-0528718111int:CEP250
InteractionCEP192 interactions

KRT8 CEP350 SYNE3 AP2B1 FEZ1 CLTA XRN1 LZTS2 PCNT

6.16e-051921819int:CEP192
InteractionKIAA1671 interactions

KRT8 CALD1 SYNE3 AP2B1 NISCH CLTA PAN2 LZTS2 PCNT

6.67e-051941819int:KIAA1671
InteractionNINL interactions

KRT8 RPLP2 CEP290 LCN1 DDB1 CEP350 VPS52 PROSER3 CEP250 XRN1 COBL LZTS2 DNMBP PCNT

7.07e-0545818114int:NINL
InteractionKIAA0753 interactions

KRT8 CEP290 CEP350 SYNE3 RNF6 XRN1 LZTS2 PCNT

8.88e-051571818int:KIAA0753
InteractionEED interactions

DCAF1 IPO5 RRAS2 KRT8 RANGAP1 GALK1 DSG2 RPLP2 CAPN2 CEP290 INTS1 OBSCN LAMA5 MCM4 RBM28 DDB1 DHX15 RIF1 UTP18 AP2B1 SUPT6H SLTM PALM3 PLEC LZTS2 MAP2K3 HNRNPR PCNT

9.31e-05144518128int:EED
InteractionKCNA3 interactions

DOCK1 NCOA2 IPO5 PALD1 RANGAP1 CALD1 DSG2 ABCA13 MYH7B RNF213 MCM4 CC2D1B CPD DDB1 RYR1 DHX15 XRN1 TCF25 ANKRD17 COBL

1.15e-0487118120int:KCNA3
GeneFamilyEF-hand domain containing

CABP5 CETN2 CAPN2 NUCB1 RYR3 TCHH RASEF EFCC1 CAPS2

1.45e-052191199863
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

1.28e-0431192287
GeneFamilyProtein phosphatase catalytic subunits|STRIPAK complex

CTTNBP2 STRIP2 STK25

2.92e-042011931371
GeneFamilyBardet-Biedl syndrome associated|BBSome

IFT172 CEP290 BBS9

3.39e-04211193980
GeneFamilyMitogen-activated protein kinase kinases

MAP2K2 MAP2K3

8.83e-0471192653
CoexpressionGSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN

RANGAP1 NUCB1 NCF4 DDB1 VPS52 AP2B1 SUPT6H NISCH MAP2K2

1.16e-052001829M5977
CoexpressionGSE17721_LPS_VS_CPG_16H_BMDC_UP

CABP5 IFT172 FHOD3 LAP3 TRAK1 PLA1A RAPGEF3 HELZ2 PCNX1

1.16e-052001829M4007
CoexpressionGSE12839_CTRL_VS_IL12_TREATED_PBMC_DN

HECW1 FOXN3 ADCY8 TRAK1 SEMA3D GSDME PYGM

3.07e-051271827M441
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK1 NCOA2 RRAS2 SLC4A7 BTAF1 FOXN3 REV3L PNISR TRAK1 CEP350 DHX15 RIF1 UTP18 ANKRD17 TNKS DNMBP MED13 PCNT

3.12e-0585618218M4500
CoexpressionSMID_BREAST_CANCER_BASAL_DN

KRT8 SLC4A7 SLC4A8 ABCA12 CPD ITGA7 OGN TRAK1 CRY2 ATP8A1 PLA1A RAPGEF3 SUPT6H AFP PAN2 DNMBP

3.21e-0569918216M4960
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN

NUCB1 INTS1 IRF4 NCF4 SMG5 PNISR BCS1L STRIP2 DIP2A VPS52 SLC16A5 NISCH HELZ2 TCF25 PAN2 SLC4A5 PCNT STK25

6.38e-0590518218M40865
CoexpressionPETRETTO_HEART_MASS_QTL_CIS_UP

OGN VPS52 RNF6 PLEC

6.95e-05321824M17037
CoexpressionGSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_DN

IPO5 RRAS2 SLC4A8 VPS33A POLR1F AP1B1 CEP250 ZNF579

7.67e-051981828M6033
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN

SLC4A8 IFT172 IRF4 CPD SEMA3D SUPT6H SKAP1 PHLDB2

7.67e-051981828M9234
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_PROJECTION_NEURONS

HECW1 LDB2 RYR3 TRAK1 SLC8A1 PCNX1 KLHL8

7.80e-051471827MM414
CoexpressionGSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN

TRIM72 RETREG2 KIF26B NCF4 PNISR CEP350 HELZ2 ZNF579

7.94e-051991828M7451
CoexpressionGSE2826_WT_VS_BTK_KO_BCELL_UP

RETREG2 NCF4 SMG5 CRY2 CEP350 CLTA ANKRD17 PLEC

8.22e-052001828M4898
CoexpressionGSE360_CTRL_VS_L_DONOVANI_MAC_UP

KRT8 SLC4A7 NUCB1 FOXN3 DDB1 AP1B1 MAP2K3 CDH5

8.22e-052001828M5157
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

SEMA6C SLC4A7 CDHR2 HKDC1 BMP1 GSDME MYH14 CREB3L3 PLEC

8.75e-052591829M40029
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500

DOCK1 KRT8 DSG2 LAMA5 HKDC1 CPD REV3L PNISR CEP350 SEMA3D SLC8A1 TCHH SLC16A5 AFP ANKIB1 MED13

2.33e-0739018016gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

DOCK1 RRAS2 KRT8 DSG2 LAMA5 HKDC1 CPD REV3L PNISR CEP350 SEMA3D SLC8A1 TCHH ATP8A1 IFTAP SLC16A5 AFP RAB3IP ANKIB1 MED13

9.79e-0677418020gudmap_developingKidney_e15.5_cortic collect duct_1000
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500

DOCK1 RRAS2 KRT8 DSG2 LAMA5 HKDC1 FHOD3 REV3L SEMA3D TCHH SLC16A5 AFP RAB3IP MED13

1.01e-0540618014gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

MORC1 SEMA6C RANGAP1 SLC4A7 CALD1 RNF213 CPD PNISR RIF1 GSDME ATP8A1 IFTAP PHF20L1 PLA1A AFP NISCH ANKRD17 CAPS2 PLEC HNRNPR

1.76e-0580618020gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

NCOA2 SEMA6C NES SLC4A8 CEP290 FHOD3 POU6F1 FOXN3 IRGQ ZNF235 BBS9 CEP350 DIP2A ATP8A1 FEZ1 RTL1 ZNF579

1.98e-0561418017Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000

SEMA6C SYNPO2 SLC4A8 DSG2 KIF26B RNF213 NCF4 POU6F1 FOXN3 ZNF235 ADCY8 BMP1 DIP2A SEMA3D SLC8A1 FEZ1 MYH14 RTL1 PALM3 EFCC1 ZNF579 TVP23A

2.48e-0596718022Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

SEMA6C SYNPO2 SLC4A8 DSG2 KIF26B RNF213 NCF4 POU6F1 FOXN3 ZNF235 ADCY8 BMP1 DIP2A SEMA3D SLC8A1 FEZ1 MYH14 RTL1 PALM3 EFCC1 ZNF579 TVP23A

2.48e-0596718022Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_500

MORC1 CPD RIF1 AFP NISCH HNRNPR

3.35e-05721806gudmap_developingGonad_e16.5_ovary_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000

DOCK1 RRAS2 KRT8 DSG2 LAMA5 HKDC1 FHOD3 CPD REV3L CEP350 SEMA3D RIF1 TCHH SLC16A5 AFP SKAP1 RAB3IP DNMBP MED13

5.30e-0580118019gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NCOA2 SLC4A7 SLC4A8 CEP290 REV3L PNISR RIF1 SLTM ANKIB1 PALM3 ZNF579

7.34e-0531118011Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500

DOCK1 CPD REV3L PNISR CEP350 SEMA3D SLC8A1 MED13

7.76e-051631808gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_1000

CALD1 BMP1 RIF1 GSDME FEZ1 NISCH HNRNPR

9.15e-051241807gudmap_developingGonad_e16.5_epididymis_1000_k1
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_500

KRT8 DSG2 LAMA5 HKDC1 TCHH SLC16A5

1.11e-04891806gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

DOCK1 ABCA13 FHOD3 CPD REV3L PNISR CEP350 SEMA3D SLC16A5 PLA1A AFP SKAP1 RAB3IP ANKIB1 TNKS DNMBP MED13 STK25

1.50e-0479518018gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#1

SEMA6C SLC4A8 POU6F1 FOXN3 ZNF235 DIP2A FEZ1 RTL1 ZNF579

1.74e-042331809Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K1
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 CPD REV3L PNISR RIF1 TNKS MED13

2.52e-041461807gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#1_top-relative-expression-ranked_1000

CALD1 RIF1 GSDME FEZ1 NISCH HNRNPR

2.74e-041051806gudmap_developingGonad_e18.5_epididymis_1000_k1
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 DSG2 SPTB OBSCN FHOD3 RYR3 STRIP2 SLC8A1 MYH14 PYGM

6.82e-091911821097fb4232417a39801e87725755fd16a57c250209
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 DSG2 SPTB OBSCN FHOD3 RYR3 STRIP2 SLC8A1 MYH14 PYGM

6.82e-091911821064070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PALD1 CPAMD8 KIF26B LAMA5 LAP3 LDB2 HELZ2 EFCC1 CDH5

5.86e-081801829d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 DSG2 SPTB OBSCN FHOD3 STRIP2 SLC8A1 CDH22 PYGM

9.74e-081911829c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 DSG2 SPTB OBSCN FHOD3 STRIP2 SLC8A1 CDH22 PYGM

9.74e-081911829715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT8 HKDC1 BCAN ATP8A1 MYH14 COBL RASEF PLA2G4F SLC4A5

1.02e-071921829f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 REV3L DDB1 RAD51AP2 RIF1 SLC8A1 NISCH XRN1 PHLDB2

1.16e-0719518297796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

TRIM72 RAPSN HECW1 SPTB RYR1 COBL PYGM PCNT

2.55e-071551828d7e26696fd9c0a759524f331243db43059b33ed9
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 CDHR2 HKDC1 MYH14 ANKIB1 CREB3L3 PLEC PDLIM2

6.14e-0717418287c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 CDHR2 HKDC1 MYH14 ANKIB1 CREB3L3 PLEC PDLIM2

6.14e-0717418282fbdb62e269acf4447b171700a615e878dde7f9f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANGAP1 CDHR2 CAPN2 OBSCN TMEM63C LAMA5 STRIP2 MYH14

6.14e-071741828207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 CDHR2 ABCA12 HKDC1 SLC8A1 SLC16A5 MYH14 PDLIM2

6.70e-0717618287622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO2 CALD1 HECW1 ITGA10 ITGA7 SLC4A3 MAP3K15 TAB1

7.93e-071801828a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO2 CALD1 HECW1 ITGA10 ITGA7 SLC4A3 MAP3K15 TAB1

7.93e-07180182863a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 CALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5 PHLDB2

8.27e-071811828e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 MYH7B SPTB OBSCN FHOD3 SLC4A3 SLC8A1 PXDNL

9.36e-071841828e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 CALD1 OBSCN ITGA10 LAMA5 REV3L TGFBI EFCC1

1.10e-061881828997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN DSG2 FHOD3 SLC4A3 RYR3 STRIP2 CDH22 MYH14

1.15e-061891828b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN DSG2 FHOD3 SLC4A3 RYR3 STRIP2 CDH22 MYH14

1.15e-061891828e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES SYNPO2 CALD1 OBSCN ITGA10 LAMA5 LDB2 CDH5

1.19e-0619018280a351609a72fd638c84b2435782e312ee6a33aac
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB OBSCN FHOD3 STRIP2 SLC8A1 MYH14 PYGM

1.29e-061921828f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB OBSCN FHOD3 STRIP2 SLC8A1 MYH14 PYGM

1.29e-0619218281a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NES SYNPO2 DSG2 IRF4 STRIP2 CEP350 ATP8A1 TVP23A

1.34e-0619318287426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NES SYNPO2 DSG2 IRF4 STRIP2 CEP350 ATP8A1 TVP23A

1.34e-061931828a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

RPLP2 CEP290 RBM28 PNISR CEP350 NISCH SLTM TCF25

1.56e-0619718280fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellBAL-Severe-cDC_10|Severe / Compartment, Disease Groups and Clusters

NES SYNPO2 DSG2 IRF4 STRIP2 CEP350 ATP8A1 TVP23A

1.68e-06199182854bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-062001828032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-06200182868fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-062001828878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-062001828376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-0620018287fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

UNC13B DOCK1 SYNPO2 CALD1 CAPN2 BBS9 PLEKHH3 CDH5

1.75e-0620018287136936d05ab344a560cf159684c881063b5430d
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN EID3 CDHR2 STRIP2 RAPGEF3 SKAP1 PALM3

4.20e-061591827e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN EID3 CDHR2 STRIP2 RAPGEF3 SKAP1 PALM3

4.20e-0615918279db971130509c62d439e0cab16588a4d994d7aa0
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYH7B ITGA10 TGFBI SLC16A5 CEP250 PALM3 COBL

5.15e-061641827dcd3c3ee73900180451fad9b4de0efedbd375e1c
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYH7B ITGA10 TGFBI SLC16A5 CEP250 PALM3 COBL

5.15e-061641827dd29decc6c41a580cfdf03962827ec18d432935f
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ZNF235 LDB2 SEMA3D SYNE3 SKAP1 PLEC

5.80e-061671827fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ZNF235 LDB2 SEMA3D SYNE3 SKAP1 PLEC

5.80e-061671827f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ZNF235 LDB2 SEMA3D SYNE3 SKAP1 PLEC

5.80e-061671827b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ZNF235 LDB2 SEMA3D SYNE3 SKAP1 PLEC

5.80e-06167182726cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO5 PRICKLE4 SYNPO2 CALD1 FHOD3 RYR3 SEMA3D

6.77e-06171182709e653973962fb884878089d281f0947f7a285f6
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO5 PRICKLE4 SYNPO2 CALD1 FHOD3 RYR3 SEMA3D

6.77e-06171182782de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 CDHR2 ABCA12 HKDC1 SLC8A1 SLC16A5 ANKIB1

7.30e-061731827e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 CDHR2 ABCA12 HKDC1 SLC8A1 SLC16A5 ANKIB1

7.30e-06173182799532bb768ee35fed939a377acb5215d3f8904bd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5 NLRP13

8.48e-061771827c8a51e480b978dc0ded85583261f2c892e085be8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5 NLRP13

8.48e-061771827c274fbdc141855ff4581d437d4997c64cc193278
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5 NLRP13

8.48e-061771827f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MORC1 SYNPO2 CALD1 CETN2 OGN FEM1B FEZ1

8.48e-06177182788403b055eb9fdf96e4695fb6e0d78179e30a1e3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MORC1 SYNPO2 CALD1 CETN2 OGN FEM1B FEZ1

8.48e-0617718278903aeaab61abd81a148ea623038c5114b8a183b
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PALD1 NES CPAMD8 CALD1 ITGA10 LDB2 CDH5

9.81e-06181182761608123959483ff60f07d8467996853c4371b6a
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 MYH7B SPTB OBSCN FHOD3 SLC8A1 PXDNL

9.81e-061811827719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

SYNPO2 CTTNBP2 CALD1 FHOD3 ITGA7 BCS1L RYR3

1.02e-051821827ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 CALD1 LDB2 SEMA3D EFCC1 CDH5 PHLDB2

1.05e-0518318274d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 ABCA12 ABCA13 KIF26B OBSCN RYR3 SLC8A1

1.09e-0518418272cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 ABCA12 ABCA13 KIF26B OBSCN RYR3 SLC8A1

1.09e-0518418272b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

PALD1 NES CPAMD8 CALD1 ITGA10 LDB2 CDH5

1.09e-0518418275f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 ABCA12 ABCA13 KIF26B OBSCN RYR3 SLC8A1

1.09e-051841827ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 MYH7B SPTB OBSCN FHOD3 SLC8A1 PXDNL

1.13e-051851827549eeb521c3985bff396ea0f202db21822efa51f
ToppCelldroplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HKDC1 BCAN ITGA7 MYH14 COBL PLA2G4F SLC4A5

1.13e-0518518276938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCelldroplet-Lung-nan-21m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HKDC1 BCAN ITGA7 MYH14 COBL PLA2G4F SLC4A5

1.13e-0518518270e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB FHOD3 SLC4A3 STRIP2 CDH22 MYH14

1.17e-051861827337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB FHOD3 SLC4A3 STRIP2 CDH22 MYH14

1.17e-051861827e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 CALD1 LDB2 SEMA3D EFCC1 CDH5 PHLDB2

1.17e-05186182740070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 CALD1 LDB2 SEMA3D EFCC1 CDH5 PHLDB2

1.17e-05186182720340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7B SPTB OBSCN FHOD3 SLC4A3 STRIP2 MYH14

1.21e-051871827c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7B SPTB OBSCN FHOD3 SLC4A3 STRIP2 MYH14

1.21e-051871827362e56426a568423a81e8a30e3ecf99b76135843
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 MYH7B SPTB FHOD3 SLC4A3 STRIP2 MYH14

1.25e-0518818274db566f3f708e66730aa9e16f4d73d91dc534177
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

PALD1 NES CALD1 OBSCN ITGA10 LDB2 CDH5

1.25e-051881827e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 MYH7B SPTB FHOD3 SLC4A3 STRIP2 MYH14

1.25e-0518818276704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 SYNE3 EFCC1 CDH5

1.34e-051901827876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 RYR3 SEMA3D PLA1A ITPRIP CDH5

1.34e-051901827656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCelldroplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES SYNPO2 CALD1 ITGA7 OGN PLEKHH3 PYGM

1.34e-051901827e04f47705851563515b6a66a2634cf7a574f7bda
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES SYNPO2 CALD1 ITGA7 OGN PLEKHH3 PYGM

1.34e-0519018271803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 SYNE3 EFCC1 CDH5

1.34e-05190182709a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

RRAS2 CALD1 MYH7B OBSCN FHOD3 SLC8A1 PHLDB2

1.34e-05190182793c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

NES CABP5 CALD1 LDB2 PLA1A RAPGEF3 CDH5

1.34e-0519018276e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNPO2 CALD1 MYH7B SPTB OBSCN ITGA7 PXDNL

1.34e-051901827918ad5037881212008f9f69d5df5da91fd01422c
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NCF4 RYR1 TGFBI SLC8A1 TCHH TLR2 DNMBP

1.34e-0519018272d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

SPTB FHOD3 STRIP2 PXDNL COBL ITPRIP KLHL8

1.34e-0519018273729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 LDB2 SEMA3D CDH22 SYNE3 EFCC1 CDH5

1.34e-051901827be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

UNC13B CPAMD8 LAMA5 MALRD1 ATP8A1 MYH14 COBL

1.39e-051911827d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT8 HKDC1 BCAN ATP8A1 MYH14 RASEF PLA2G4F

1.44e-05192182713e4b17d7a592604140777aca235f795df6b3f91
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT8 HKDC1 BCAN ATP8A1 MYH14 RASEF PLA2G4F

1.44e-0519218276244541688f85917018a057aa0b3e5972934dfbc
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB OBSCN STRIP2 SLC8A1 MYH14 PYGM

1.44e-0519218270bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 SPTB OBSCN STRIP2 SLC8A1 MYH14 PYGM

1.44e-051921827d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 ABCA13 RNF213 SLC16A5 MYH14 SKAP1 COBL

1.54e-051941827e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellproximal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 BTAF1 TCHH PLA1A TLR2 TVP23A AIM2

1.59e-0519518278592d0332bc82a91e173680cfd1afc5ee189b289
ToppCellproximal-Hematologic-IGSF21+_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 BTAF1 TCHH PLA1A TLR2 TVP23A AIM2

1.59e-051951827c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCellproximal-Hematologic-IGSF21+_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 BTAF1 TCHH PLA1A TLR2 TVP23A AIM2

1.59e-051951827ae9d61011e95f7840cbb154738c79745fd29943e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 REV3L RAD51AP2 RIF1 SLC8A1 NISCH PHLDB2

1.59e-0519518273e519cffa6144a62b06124642a14c9ff39b76554
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UNC13B NES CALD1 LAMA5 ITGA7 RYR3 CDH5

1.64e-051961827b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CALD1 ITGA10 OGN BMP1 RTL1 PXDNL PDLIM2

1.70e-0519718272872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 RNF213 NCF4 RYR1 SLC8A1 AP1B1 TLR2

1.70e-05197182710190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

RNF213 FOXN3 PNISR LAP3 HELZ2 XRN1 TCF25

1.70e-0519718275c33454b10023decd2f5ccda9229b6512659711e
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

NES SYNPO2 CALD1 ITGA10 LAMA5 ITGA7 TGFBI

1.75e-051981827f540f464118edc0fb809ebcb813d0302e6952253
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 CALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5

1.75e-0519818279ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM72 SYNPO2 CALD1 HECW1 ITGA7 SEMA3D SLC8A1

1.75e-051981827d1827e3707b929e3a3562989a0c11537d344e164
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 CALD1 LDB2 SEMA3D CDH22 EFCC1 CDH5

1.75e-051981827e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

NES SYNPO2 DSG2 IRF4 STRIP2 ATP8A1 TVP23A

1.75e-05198182790f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

NES SYNPO2 CALD1 SPTB LAMA5 ITGA7 TGFBI

1.81e-051991827d65847ceb68a560798df3f73e6f838e7c3e38a1c
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A8 SLC4A3 SLC4A5

1.62e-06151774DOID:2355 (implicated_via_orthology)
DiseaseJT interval

NCOA2 SLC4A7 RAPSN OBSCN FHOD3 FOXN3 RBM28 SLC4A3 SLC8A1 ZNF579

2.76e-0624817710EFO_0007885
Diseasecataract

CPAMD8 PLEKHH3 DIP2A PROSER3 TNKS DNMBP PCNT

2.39e-051411777MONDO_0005129
Diseasecystic kidney disease (implicated_via_orthology)

IFT172 CEP290 LAMA5

2.47e-05101773DOID:2975 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

1.07e-0431772DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

1.07e-0431772DOID:8545 (implicated_via_orthology)
Diseaserespiratory symptom change measurement, response to placebo

BBS9 ADCY8 DHX15

1.36e-04171773EFO_0008344, EFO_0010068
DiseaseWaldenstrom macroglobulinemia

IRF4 SYNE3

3.54e-0451772EFO_0009441
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

RAPSN RYR1

5.28e-0461772C1854678
Diseaselevel of Sphingomyelin (d36:2) in blood serum

RAPSN ANKRD17

7.37e-0471772OBA_2045177
Diseaselysophosphatidylcholine 22:4 measurement

RAPSN SYNE3

7.37e-0471772EFO_0021461
Diseaseright ventricular ejection fraction measurement

OBSCN FHOD3 PLEC

7.65e-04301773EFO_0021816
Diseasemean reticulocyte volume

KRT8 RAPSN RETREG2 SPTB MCM4 LDB2 CEP350 DIP2A PHF20L1 AP2B1 HELZ2 MAP2K2 MAP2K3

1.12e-0379917713EFO_0010701
Diseasewaist-hip ratio

CPAMD8 RRAS2 RAPSN TMEM63C ITGA7 ADCY8 SEMA3D UTP18 RAPGEF3 NISCH XRN1 PCNX1 TAB1 CREB3L3 MAP2K3 PHLDB2 HNRNPR

1.18e-03122617717EFO_0004343
DiseaseRASopathy (implicated_via_orthology)

RRAS2 MAP2K2

1.25e-0391772DOID:0080690 (implicated_via_orthology)
DiseaseCataract

CPAMD8 GALK1 INTS1

1.42e-03371773C0086543
Diseasecerebral cavernous malformation (implicated_via_orthology)

RNF213 STK25

1.90e-03111772DOID:0060669 (implicated_via_orthology)
DiseaseDental enamel hypoplasia

MYH7B MYH14

2.27e-03121772EFO_1001304
DiseaseCongenital muscular dystrophy

ITGA7 RYR1

2.27e-03121772cv:C0699743
DiseaseADHD symptom measurement

CALD1 FOXN3

2.27e-03121772EFO_0007860
Diseasecognitive impairment measurement

UNC13B PXDNL CDH5

2.35e-03441773EFO_0007998
Diseaseserum alanine aminotransferase measurement

KRT8 GALK1 RAPSN MYH7B LAMA5 HKDC1 SSR1 FEZ1 RASEF TNKS CREB3L3 KLHL8 DNMBP

2.35e-0386917713EFO_0004735
Diseaselevel of Sphingomyelin (d34:2) in blood serum

RAPSN ANKRD17

2.67e-03131772OBA_2045174
DiseaseBardet-Biedl Syndrome

IFT172 CEP290

2.67e-03131772C0752166
Diseasephosphatidylcholine 36:5 measurement

RAPSN RASEF

3.11e-03141772EFO_0010383
Diseasecorpus callosum volume measurement

CTTNBP2 KIF26B POLR1F PLEC

3.14e-031001774EFO_0010299
Diseaseaspartate aminotransferase measurement

KRT8 SLC4A7 MYH7B OBSCN HKDC1 RNF213 DHX15 AP1B1 FEZ1 TNKS KLHL8 TVP23A DNMBP

3.29e-0390417713EFO_0004736
DiseaseDuchenne muscular dystrophy, disease progression measurement

DOCK1 ADCY8 SLC8A1

3.38e-03501773EFO_0008336, MONDO_0010679
DiseaseColorectal Carcinoma

UNC13B CPAMD8 ABCA12 ABCA13 OBSCN ADCY8 CDH22 TLR2 PAN2 LZTS2 CDH5

3.55e-0370217711C0009402
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

MYH7B MYH14

3.57e-03151772EFO_0006833, EFO_0006896
Diseasebody mass index, fasting blood glucose measurement

RAPSN FOXN3 CRY2

3.58e-03511773EFO_0004340, EFO_0004465
Diseaseneutrophil collagenase measurement

ABCA13 DNMBP

4.06e-03161772EFO_0008248
DiseaseBardet-Biedl syndrome 1 (disorder)

CEP290 BBS9

4.59e-03171772C2936862
Diseasephosphoglyceric acid measurement

SUSD1 TVP23A

4.59e-03171772EFO_0010523
DiseaseMoyamoya Disease

RNF213 PCNT

4.59e-03171772C0026654
Diseaseelectrocardiography

NCOA2 OBSCN FHOD3 FOXN3 SLC4A3 TRAK1 SLC8A1 PCNX1 PLEC

4.88e-035301779EFO_0004327
Diseasesweet liking measurement

TMEM63C RGS9BP

5.14e-03181772EFO_0010156
Diseasetriacylglycerol 56:3 measurement

RAPSN MAP3K15

5.14e-03181772EFO_0010430
DiseaseCongenital Fiber Type Disproportion

ITGA7 RYR1

5.14e-03181772C0546264
DiseaseBardet-Biedl syndrome

CEP290 BBS9

5.14e-03181772cv:C0752166
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

AP1B1 CCDC40

5.72e-03191772DOID:9562 (implicated_via_orthology)
Diseaselevel of Sphingomyelin (d38:2) in blood serum

RAPSN ANKRD17

5.72e-03191772OBA_2045179

Protein segments in the cluster

PeptideGeneStartEntry
ERGDELADSALEIFK

TGFBI

641

Q15582
LNEIIADFDELLGED

ADCY8

1011

P40145
ADDRQDLLSAISEFL

SLC4A3

591

P48751
VEDQGFLDSLRDLIA

AP2B1

156

P63010
AERIDNADELLESFL

AP2B1

456

P63010
RLDLGSLVDSDDEDN

CAPS2

66

Q9BXY5
DSFELLDLLFDRQDG

CREB3L3

21

Q68CJ9
ESEFDLQLLEAAELG

ABCA12

466

Q86UK0
LEDVDAAFLSRDLAV

BCS1L

281

Q9Y276
LTGLDNITDEELDRF

AIM2

11

O14862
TRNFLREVDADGDLI

GSDME

6

O60443
REVDADGDLIAVSNL

GSDME

11

O60443
FDELDALAVERGSSL

SPATA5

726

Q8NB90
EDFLDLRDFLVALGN

ABCA13

1226

Q86UQ4
ESGLALDEETRDFLS

ANKIB1

866

Q9P2G1
LSAQLDEELDFREGD

DNMBP

156

Q6XZF7
AERIDNADELLESFL

AP1B1

456

Q10567
LIERGASLEEVNDEG

ANKRD17

486

O75179
DLLLFLTGQEEIDEA

DHX15

351

O43143
QEIREAFDLFDADGT

CETN2

31

P41208
AFLGDIALDEEDLRA

BMP1

51

P13497
DAETGDVFAIERLDR

CDH5

96

P33151
ALDEVDEQLFRSVEG

EFCC1

376

Q9HA90
GDALRKENDFALIID

ATP8A1

731

Q9Y2Q0
ENGLVFEDSEELAAL

ALG1L

101

Q6GMV1
LRLLAEGFDDETEDQ

AP4E1

471

Q9UPM8
ELKDDDFERISELGA

MAP2K2

66

P36507
FDSLTRIENDFELEE

RAD51AP2

591

Q09MP3
LEAEGDFDVADLREL

RGS9BP

136

Q6ZS82
EDFDSLEALRLEGNT

RANGAP1

46

P46060
NLSFDSEEEELGELL

RBM28

341

Q9NW13
DTARELEDADFLLES

RAPSN

71

Q13702
LDAIERAQDLAEEVG

RAPSN

306

Q13702
GQELEELTASLFEEA

RAB3IP

206

Q96QF0
DAEAVFQRLDADRDG

RASEF

46

Q8IZ41
REFLEGFVDDLLEAL

ITPRIP

161

Q8IWB1
EDFDQLLEALRAALS

PALD1

636

Q9ULE6
LQERLEAAASIEGED

PALM3

306

A6NDB9
LEAAIADAEQRGELA

KRT8

331

P05787
ALAELLDNARDAGAE

MORC1

31

Q86VD1
LDNARDAGAERLDVF

MORC1

36

Q86VD1
LDDGLDEAFSRLAQS

LDLRAP1

251

Q5SW96
DNTDAEGRLILADAL

LAP3

361

P28838
FIEGELDDRFLDDLG

DSG2

816

Q14126
LADVLEGDSSEDRAF

BCAN

21

Q96GW7
ALLAEDGNLVSLEED

C22orf15

41

Q8WYQ4
EEALRALADDDFLTV

MCM4

841

P33991
FVTLNEEEAELRSDG

PAN2

981

Q504Q3
LNLEDQGALLSDDEI

DCAF1

496

Q9Y4B6
ELEARELADLGLAEQ

LZTS2

641

Q9BRK4
VLLDEIEAAELEGND

INTS1

121

Q8N201
DFEELVERSQLDISD

IRF4

106

Q15306
QLDLGEEASALLLED

HECW1

461

Q76N89
FAELQERLDCIDGSE

KIF26B

926

Q2KJY2
EFGDEDERLITRLEN

LDB2

311

O43679
GQDEIEELREAFLEF

CABP5

26

Q9NP86
EALELLGASFANDRE

FEM1B

251

Q9UK73
RELDSAQFQEGLELE

TMEM63C

786

Q9P1W3
LTEALEEANVLFDGV

EID3

66

Q8N140
EAAGLREQLEEEAAA

MYH14

1361

Q7Z406
AAELEELRAALEQGE

MYH7B

1731

A7E2Y1
DSLEEDLDFLRDQFT

VBP1

156

P61758
EGSEEQDLAADRKLF

PCNX1

196

Q96RV3
TLIEIRDFDGDAIED

KLHL8

106

Q9P2G9
EELEAARDLVSKEGF

GALK1

261

P51570
DALREFNEEGALSVL

HNRNPR

66

O43390
EDIALNYRDAEGDLV

NCF4

281

Q15080
SLDEDGINLEEIREF

POU6F1

136

Q14863
AAEVARDNLAEELEG

NES

76

P48681
NLEALEDFEKAAGAR

LCN1

141

P31025
RRLDFTGNLIEDIED

OGN

146

P20774
LDQVEGAIRDFSEEL

FEZ1

236

Q99689
LNLEEEFDGVLREEA

LRGUK

96

Q96M69
DEDIGEQFAAVSLDR

LAMA5

2821

O15230
VFDEADRILDLGFEK

DDX31

386

Q9H8H2
DIAAELARNLIDEDG

IPO5

111

O00410
SDGVLDEQELEALFT

NUCB1

256

Q02818
DLDLRLGFDLSDGEQ

PLA2G4F

311

Q68DD2
LGFDLSDGEQEFLDR

PLA2G4F

316

Q68DD2
ILDSVGIEADDDRLN

RPLP2

26

P05387
GAEEAAELQLAELER

PCNT

1826

O95613
DGAQAEDLLLEVDLR

BBS9

61

Q3SYG4
FLNRFLDLTDAIEEG

IFT172

1596

Q9UG01
DLNSVFLRVLDDEDS

IFNAR2

426

P48551
SEDVDALLAEAAVGR

OBSCN

7371

Q5VST9
ALGEEERAELQLFCA

PRICKLE4

46

Q2TBC4
LDGNEDIFIALDDIS

MALRD1

1871

Q5VYJ5
EERIAEAEIENLTGA

OTUD6B

116

Q8N6M0
GAEADRELEELLESA

PEX19

11

P40855
LEDDTRLNVFDDGTL

PXDNL

276

A1KZ92
GSLDREQLLEADEEV

CDHR2

301

Q9BYE9
EILGDEVQLFSLDEE

IFTAP

166

Q86VG3
DLDLVVRDEDGNILD

DOCK1

161

Q14185
IEGLQDLDDDVRAVA

BTAF1

436

O14981
GVRVFDELLLDADFS

CRY2

396

Q49AN0
FLDENEALRERVGLE

CEP290

496

O15078
LDQRLSLGSDDEADL

CTTNBP2

1516

Q8WZ74
EGADDSLDEFRINIL

C19orf44

351

Q9H6X5
QEDDDLDFSLPDIRL

FOXN3

36

O00409
GFRADIESLEQLLLD

CPAMD8

1581

Q8IZJ3
QADFDTLEADLTRLG

CCDC40

1041

Q4G0X9
AEEAGAELQADLRDI

CEP250

671

Q9BV73
ASNDEEDLLIAGEFR

COBL

476

O75128
AGEFRKTLAELDEDL

COBL

486

O75128
DLEATLAEQRDELEG

FHOD3

71

Q2V2M9
EDLEAELLALTGEAQ

CC2D1B

46

Q5T0F9
EEELESALREAAAAG

CPD

61

O75976
ELELSREFLSALGDD

CEP350

2856

Q5VT06
DLEGDAQSVLDAREL

ADPRS

221

Q9NX46
DGRLDLDGDDLVDVA

ITGA10

616

O75578
LSQDLAIRDELDGGE

ITGA7

166

Q13683
AIDRESDLDQIFDID

CDH22

431

Q9UJ99
VELDGLEQDALDLVA

DIP2A

1501

Q14689
GELNADDAILRELLD

HELZ2

1066

Q9BYK8
SEDDIDDGFRRLFAQ

CAPN2

526

P17655
RLFAQLAGEDAEISA

CAPN2

536

P17655
EAQEGELLVRDEFSV

RYR1

3386

P21817
FAEDLVLDEEGARAA

ESRRA

286

P11474
AVEILDDDNFLGAEN

DDB1

956

Q16531
FEVLGAAELEAVREA

IRGQ

186

Q8WZA9
EQLEAVIADFSGLLE

AFP

566

P02771
VDLSGENLSDVDFLD

PHF20L1

631

A8MW92
TIGDRNFEVEADDLV

MAP2K3

51

P46734
EDRDQGLFLLRKDSE

MAP3K15

996

Q6ZN16
NLFSSLREEEIDDIG

MIEF2

426

Q96C03
GDEDVVLREALQDDL

RTL1

1226

A6NKG5
FGDVENDEDALLRRL

UTP18

96

Q9Y5J1
DRNDLLSGIDEFLDQ

SLC4A7

506

Q9Y6M7
RFENLAAEEAGLEDS

PLEKHH3

471

Q7Z736
RGLLAVAQDLTEDEE

SSR1

26

P43307
AIGADSARFEELLLQ

PIH1D1

16

Q9NWS0
NELAGVDTELLAERF

SMG5

186

Q9UPR3
ELERQDEALDGVAAA

SNAP47

431

Q5SQN1
GERTLDGELDLLEQD

STRIP2

381

Q9ULQ0
GDAESQEAEFERLVA

SYNE3

681

Q6ZMZ3
NEDELFRLSQLGLDA

TAB1

211

Q15750
EDIRTEFDRELDLGS

HKDC1

271

Q2TB90
SLEDEGFSNLLFVDR

RIF1

741

Q5UIP0
SEQEAGLGLDLDLDR

SLC26A8

866

Q96RN1
ALTTEDFELLDQGEL

RETREG2

486

Q8NC44
DAITLDFDGDDLLET

SLTM

251

Q9NWH9
FFLLNESDDDDRIRG

RNF6

591

Q9Y252
AARLDILDTAGQEEF

RRAS2

61

P62070
ADARLSFLLDQAEDL

PROSER3

436

Q2NL68
AKERDDLLAGIDEFL

SLC4A8

376

Q2Y0W8
FLEDELDIIGRNTDC

MED13

1141

Q9UHV7
GSVEFDEADLESLRQ

PHLDB2

386

Q86SQ0
SFRLLQEALEAEERG

PDLIM2

241

Q96JY6
GALEELENAFSLAEE

STK25

381

O00506
VSEDEAAFLASLERG

AARS2

401

Q5JTZ9
FREEDNATAALVELD

PNMA6A

56

P0CW24
EGLDFQTLLLDEERG

SEMA3D

66

O95025
TQVEGDDEAAFLERL

CALD1

86

Q05682
SEIAGIENDEAFAIL

CLTA

41

P09496
ALRNFDGLEEIDRAL

NCOA2

1086

Q15596
IILETEAADLGNDER

TRAK1

466

Q9UPV9
DLDLDAFAEELERQG

SUPT6H

1101

Q7KZ85
VEERLDAGDALFVEA

PLA1A

201

Q53H76
LLDEITRAQDLFLDG

RNF213

2721

Q63HN8
QLGELDITSDEFILD

VPS52

41

Q8N1B4
GQRTDEELDLIFEEL

RAPGEF3

226

O95398
RNADLELDEVEDFLG

TSR2

56

Q969E8
ELDEVEDFLGELLTN

TSR2

61

Q969E8
AFLGASESEVDEELL

SYNPO2

436

Q9UMS6
ELQDIDLELGVDNSA

TMEM179

151

Q6ZVK1
ADALERDLFLEAKDG

SLC16A5

431

O15375
ERIGEDFISDLDQLR

PYGM

506

P11217
DLAEFEGDFSLEGLR

REV3L

1936

O60673
AGLRAFFENAAEDLE

RYR3

2951

Q15413
EVDLLEDDGSFNISI

SUSD1

391

Q6UWL2
DIQDLLRGDAALLDA

TNKS

796

O95271
EINGITAALAEELFE

NISCH

121

Q9Y2I1
GANREADVLFEVLFD

XRN1

1131

Q8IZH2
LETDILNEDSDGLVF

TTC41P

401

Q6P2S7
RNREDLIAGIDEFLD

SLC4A5

381

Q9BY07
EDDAVAAELGLDFQR

SEMA6C

51

Q9H3T2
NEDVSLEFLRGALER

UNC13B

1076

O14795
AFEDELRGLDAHLEQ

SPTB

681

P11277
VFLAALEGSLDREAE

TRIM72

181

Q6ZMU5
ELEFEVFRLDSDAAG

POLR1F

176

Q3B726
LEAEAGRFRELAEEA

PLEC

1926

Q15149
LSLLEAREADGDVVN

PNISR

466

Q8TF01
AEIAALRFLSQLEDG

VPS33A

556

Q96AX1
DVSLDFGNEEELAFR

TVP23A

11

A6NH52
AGLTFLEELEIDASD

TLR2

171

O60603
SEEAEAGAAELRAEL

ZNF579

196

Q8NAF0
LDLDSNGRVDFNEFL

TCHH

61

Q07283
AFTEEELGLLDSAQR

ZNF235

16

Q14590
EASENGLEDIDRILE

TCF25

141

Q9BQ70
DAEEFLAEGLRNENL

SKAP1

16

Q86WV1
GRIFEVDLNILEDEE

NLRP13

656

Q86W25
ENFLDGALVLEVDER

SLC8A1

301

P32418