Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX1 ALX3 SOX9 SOX10 ZNF219 GATA2 GATA6 IRF7 POU4F1 NKX2-6 KLF4 ZNF446 ZIC3 MEOX1 USF3 SAFB SOX21 DACH2 NFATC2 NKX2-1 GLI3 ZNF589 TBR1 PROX1	1.46e-06	1459	112	24	GO:0000977
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	1.70e-06	5	112	3	GO:0030156
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX1 ALX3 SOX9 SOX10 ZNF219 GATA2 GATA6 IRF7 POU4F1 NKX2-6 KLF4 ZNF446 ZIC3 MEOX1 USF3 SOX21 DACH2 NFATC2 NKX2-1 GLI3 ZNF589 TBR1 PROX1	2.97e-06	1412	112	23	GO:0000981
GeneOntologyMolecularFunction	chromatin binding	SOX9 SOX10 ARID3A GATA2 GATA6 POU4F1 KLF4 MEOX1 CITED2 NCOR2 SAFB NFATC2 GLI3 AUTS2 ANKRD17 TBR1	3.65e-06	739	112	16	GO:0003682
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	SOX9 SOX10 TRIP6 GATA2 GATA6 SIK1 POU4F1 BCL2 KLF4 CITED2 NCOR2 NKX2-1 MED13 PROX1	4.76e-06	582	112	14	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX1 SOX9 SOX10 ZNF219 GATA2 GATA6 IRF7 POU4F1 NKX2-6 KLF4 ZNF446 ZIC3 MEOX1 SAFB SOX21 DACH2 NFATC2 NKX2-1 GLI3 TBR1 PROX1	5.00e-06	1244	112	21	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX1 SOX9 SOX10 ZNF219 GATA2 GATA6 IRF7 POU4F1 NKX2-6 KLF4 ZNF446 ZIC3 MEOX1 SAFB SOX21 DACH2 NFATC2 NKX2-1 GLI3 TBR1 PROX1	6.97e-06	1271	112	21	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	SOX1 SOX9 SOX10 GATA2 POU4F1 NKX2-6 KLF4 ZIC3 MEOX1 USF3 SOX21 NFATC2 NKX2-1	1.55e-05	560	112	13	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	SOX1 SOX9 SOX10 GATA2 POU4F1 NKX2-6 KLF4 ZIC3 MEOX1 USF3 SOX21 NFATC2 NKX2-1	1.74e-05	566	112	13	GO:0001216
GeneOntologyMolecularFunction	transcription factor binding	SOX9 SOX10 TRIP6 GATA2 GATA6 SIK1 POU4F1 BCL2 KLF4 CITED2 NCOR2 NFATC2 NKX2-1 MED13 PROX1	2.02e-05	753	112	15	GO:0008134
GeneOntologyMolecularFunction	beta-catenin binding	SOX9 CD2AP DVL3 KLF4 AXIN1 GLI3	5.92e-05	120	112	6	GO:0008013
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	TRIP6 GATA2 GATA6 POU4F1 KLF4 CITED2 NCOR2 NKX2-1 MED13 PROX1	1.21e-04	417	112	10	GO:0061629
GeneOntologyMolecularFunction	transcription coregulator activity	ARID3A ATN1 SF1 ZIC3 CITED2 KMT2C NCOR2 NKX2-1 MED22 DYRK1B MED13	3.21e-04	562	112	11	GO:0003712
GeneOntologyMolecularFunction	LBD domain binding	CITED2 PROX1	6.43e-04	7	112	2	GO:0050693
GeneOntologyMolecularFunction	protein serine kinase activity	CDK8 CDC42BPG RPS6KA2 PAK5 SIK1 MAP3K1 DYRK1B ULK1	1.02e-03	363	112	8	GO:0106310
GeneOntologyMolecularFunction	transcription coactivator activity	ATN1 ZIC3 CITED2 KMT2C NKX2-1 DYRK1B MED13	1.61e-03	303	112	7	GO:0003713
GeneOntologyMolecularFunction	protein phosphatase 2A binding	BCL2 ADCY8 SMG7	1.68e-03	42	112	3	GO:0051721
GeneOntologyMolecularFunction	protein serine/threonine/tyrosine kinase activity	RPS6KA2 MAP3K1 DYRK1B	2.33e-03	47	112	3	GO:0004712
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SOX1 CDK8 SOX9 SOX10 ZNF219 ARID3A GATA2 DVL3 GATA6 IRF7 POU4F1 NKX2-6 KLF4 MAP3K1 ZIC3 MEOX1 CITED2 KMT2C USF3 SAFB SOX21 NFATC2 NKX2-1 GLI3 MED22 AUTS2 TBR1 MED13 PROX1	1.94e-10	1390	112	29	GO:0045944
GeneOntologyBiologicalProcess	hindbrain development	CACNA1A USP9X GATA2 POU4F1 BCL2 NCOR2 PIANP SCN5A ULK1 TBR1 PROX1	1.82e-08	208	112	11	GO:0030902
GeneOntologyBiologicalProcess	neuron fate commitment	SOX1 SOX9 GATA2 POU4F1 NKX2-1 GLI3 TBR1 PROX1	3.43e-08	91	112	8	GO:0048663
GeneOntologyBiologicalProcess	head development	SOX1 CACNA1A SOX9 USP9X GATA2 DVL3 POU4F1 BCL2 NKX2-6 AXIN1 ZIC3 NCOR2 PIANP SOX21 NKX2-1 GLI3 SCN5A ULK1 TBR1 PROX1	1.04e-07	919	112	20	GO:0060322
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	SOX1 SOX9 SOX10 ZNF219 ATN1 USP9X GATA2 GATA6 SIK1 IRF7 POU4F1 KLF4 CITED2 NCOR2 SOX21 NFATC2 NKX2-1 GLI3 ZNF589 SAP130 PROX1	2.05e-07	1053	112	21	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	SOX1 SOX9 SOX10 ZNF219 ATN1 USP9X GATA2 GATA6 SIK1 IRF7 POU4F1 KLF4 SF1 AXIN1 CITED2 NCOR2 SOX21 NFATC2 NKX2-1 GLI3 ZNF589 TBR1 SAP130 PROX1	3.86e-07	1399	112	24	GO:0045892
GeneOntologyBiologicalProcess	chordate embryonic development	ALX3 SOX9 SOX10 TRIP6 USP9X GATA2 DVL3 GATA6 NKX2-6 CUBN KLF4 AXIN1 ZIC3 MEOX1 CITED2 NCOR2 GLI3 USPL1 PROX1	3.98e-07	906	112	19	GO:0043009
GeneOntologyBiologicalProcess	central nervous system development	SOX1 CACNA1A SOX9 SOX10 ATN1 USP9X GATA2 DVL3 POU4F1 BCL2 NKX2-6 ZIC3 CITED2 NCOR2 PIANP SOX21 NKX2-1 GLI3 SCN5A ULK1 TBR1 PROX1	4.07e-07	1197	112	22	GO:0007417
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	SOX1 SOX9 SOX10 ZNF219 ATN1 USP9X GATA2 GATA6 SIK1 IRF7 POU4F1 KLF4 SF1 AXIN1 CITED2 NCOR2 SOX21 NFATC2 NKX2-1 GLI3 ZNF589 TBR1 SAP130 PROX1	4.62e-07	1413	112	24	GO:1902679
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	ALX3 SOX9 SOX10 TRIP6 USP9X GATA2 DVL3 GATA6 NKX2-6 CUBN KLF4 AXIN1 ZIC3 MEOX1 CITED2 NCOR2 GLI3 USPL1 PROX1	5.81e-07	929	112	19	GO:0009792
GeneOntologyBiologicalProcess	brain development	SOX1 CACNA1A USP9X GATA2 DVL3 POU4F1 BCL2 NKX2-6 ZIC3 NCOR2 PIANP SOX21 NKX2-1 GLI3 SCN5A ULK1 TBR1 PROX1	8.45e-07	859	112	18	GO:0007420
GeneOntologyBiologicalProcess	limbic system development	USP9X NKX2-6 ZIC3 PIANP NKX2-1 GLI3 TBR1 PROX1	1.02e-06	141	112	8	GO:0021761
GeneOntologyBiologicalProcess	forebrain generation of neurons	SOX1 GATA2 NKX2-1 GLI3 TBR1 PROX1	1.43e-06	65	112	6	GO:0021872
GeneOntologyBiologicalProcess	metencephalon development	CACNA1A USP9X BCL2 NCOR2 PIANP SCN5A ULK1 PROX1	1.89e-06	153	112	8	GO:0022037
GeneOntologyBiologicalProcess	cell fate commitment	SOX1 SOX9 GATA2 GATA6 POU4F1 BCL2 KLF4 NKX2-1 GLI3 TBR1 PROX1	2.34e-06	338	112	11	GO:0045165
GeneOntologyBiologicalProcess	forebrain development	SOX1 USP9X GATA2 POU4F1 NKX2-6 ZIC3 NCOR2 PIANP NKX2-1 GLI3 SCN5A TBR1 PROX1	2.56e-06	489	112	13	GO:0030900
GeneOntologyBiologicalProcess	central nervous system neuron differentiation	SOX1 CACNA1A GATA2 POU4F1 NKX2-1 GLI3 ULK1 TBR1 PROX1	2.88e-06	217	112	9	GO:0021953
GeneOntologyBiologicalProcess	animal organ morphogenesis	SOX1 ALX3 SOX9 XIRP1 GATA2 DVL3 GATA6 NTNG1 POU4F1 BCL2 AXIN1 ZIC3 CITED2 NCOR2 NKX2-1 GLI3 SCN5A TBR1 MMP13 SOD1 PROX1	4.13e-06	1269	112	21	GO:0009887
GeneOntologyBiologicalProcess	forebrain neuron differentiation	SOX1 GATA2 NKX2-1 TBR1 PROX1	1.01e-05	53	112	5	GO:0021879
GeneOntologyBiologicalProcess	gland development	SOX9 SOX10 CD2AP GATA2 GATA6 BCL2 ZIC3 CITED2 NCOR2 NKX2-1 GLI3 SOD1 PROX1	1.06e-05	558	112	13	GO:0048732
GeneOntologyBiologicalProcess	cerebellum development	CACNA1A USP9X NCOR2 PIANP SCN5A ULK1 PROX1	1.09e-05	139	112	7	GO:0021549
GeneOntologyBiologicalProcess	forebrain neuron fate commitment	GATA2 NKX2-1 TBR1	1.28e-05	9	112	3	GO:0021877
GeneOntologyBiologicalProcess	heart development	SOX9 XIRP1 RPS6KA2 DVL3 GATA6 SIK1 POU4F1 NKX2-6 ZIC3 CITED2 NCOR2 GLI3 SCN5A MMP13 PROX1	1.48e-05	757	112	15	GO:0007507
GeneOntologyBiologicalProcess	sensory organ morphogenesis	SOX1 SOX9 GATA2 DVL3 BCL2 ZIC3 CITED2 GLI3 SOD1 PROX1	1.79e-05	343	112	10	GO:0090596
GeneOntologyBiologicalProcess	digestive tract development	SOX9 SOX10 GATA6 BCL2 NKX2-6 ZIC3 GLI3	1.95e-05	152	112	7	GO:0048565
GeneOntologyBiologicalProcess	lung epithelium development	SOX9 GATA6 NCOR2 NKX2-1 RCN3	2.01e-05	61	112	5	GO:0060428
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	ALX3 SOX9 GATA2 DVL3 AXIN1 ZIC3 CITED2 GLI3 SOD1 PROX1	2.18e-05	351	112	10	GO:0048562
GeneOntologyBiologicalProcess	neuron migration	SOX1 USP9X GATA2 NTNG1 POU4F1 NKX2-1 AUTS2 ULK1	2.54e-05	218	112	8	GO:0001764
GeneOntologyBiologicalProcess	cell differentiation in hindbrain	CACNA1A GATA2 ULK1 PROX1	2.63e-05	32	112	4	GO:0021533
GeneOntologyBiologicalProcess	hippocampus development	USP9X ZIC3 PIANP NKX2-1 GLI3 PROX1	2.73e-05	108	112	6	GO:0021766
GeneOntologyBiologicalProcess	negative regulation of developmental process	SOX9 SOX10 GATA2 BCL2 KLF4 AXIN1 CITED2 NCOR2 USF3 SOX21 NFATC2 ZFP36L2 NKX2-1 GLI3 ANKRD17 ULK1 SAP130 SOD1 PROX1	2.95e-05	1220	112	19	GO:0051093
GeneOntologyBiologicalProcess	developmental growth	SOX9 SOX10 XIRP1 ATN1 USP9X CD2AP GATA6 BCL2 CITED2 KMT2C GLI3 AUTS2 ULK1 MMP13 SOD1 PROX1	3.28e-05	911	112	16	GO:0048589
GeneOntologyBiologicalProcess	growth	SOX9 SOX10 XIRP1 ATN1 OGFR USP9X CD2AP PAK5 GATA6 BCL2 CITED2 KMT2C SAFB GLI3 AUTS2 ULK1 MMP13 SOD1 PROX1	3.49e-05	1235	112	19	GO:0040007
GeneOntologyBiologicalProcess	development of primary sexual characteristics	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 DACH2 NKX2-1 SOD1	3.54e-05	297	112	9	GO:0045137
GeneOntologyBiologicalProcess	digestive system development	SOX9 SOX10 GATA6 BCL2 NKX2-6 ZIC3 GLI3	3.57e-05	167	112	7	GO:0055123
GeneOntologyBiologicalProcess	peptidyl-threonine phosphorylation	CDC42BPG BCL2 AXIN1 DYRK1B TNKS1BP1 ULK1	3.90e-05	115	112	6	GO:0018107
GeneOntologyBiologicalProcess	male gonad development	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 NKX2-1	4.15e-05	171	112	7	GO:0008584
GeneOntologyBiologicalProcess	sensory organ development	SOX1 SOX9 GATA2 DVL3 BCL2 NKX2-6 KLF4 MAP3K1 ZIC3 CITED2 KMT2C GLI3 SOD1 PROX1	4.16e-05	730	112	14	GO:0007423
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	CACNA1A RIMBP3 RIMBP3C RIMBP3B	4.24e-05	36	112	4	GO:0007274
GeneOntologyBiologicalProcess	development of primary male sexual characteristics	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 NKX2-1	4.31e-05	172	112	7	GO:0046546
GeneOntologyBiologicalProcess	stem cell differentiation	SOX9 SOX10 GATA6 BCL2 ZIC3 MEOX1 CITED2 SOX21 ZFP36L2	4.47e-05	306	112	9	GO:0048863
GeneOntologyBiologicalProcess	ventral spinal cord interneuron differentiation	SOX1 GATA2 GLI3	5.43e-05	14	112	3	GO:0021514
GeneOntologyBiologicalProcess	peptidyl-threonine modification	CDC42BPG BCL2 AXIN1 DYRK1B TNKS1BP1 ULK1	6.22e-05	125	112	6	GO:0018210
GeneOntologyBiologicalProcess	heart morphogenesis	SOX9 XIRP1 DVL3 GATA6 POU4F1 ZIC3 CITED2 NCOR2 PROX1	6.46e-05	321	112	9	GO:0003007
GeneOntologyBiologicalProcess	cardiac muscle tissue development	XIRP1 GATA6 SIK1 POU4F1 NKX2-6 ZIC3 CITED2 SCN5A PROX1	7.45e-05	327	112	9	GO:0048738
GeneOntologyBiologicalProcess	sensory system development	SOX1 SOX9 POU4F1 BCL2 KLF4 MAP3K1 CITED2 KMT2C GLI3 ULK1 PROX1	7.50e-05	491	112	11	GO:0048880
GeneOntologyBiologicalProcess	neuron fate specification	SOX1 SOX9 POU4F1 GLI3	7.86e-05	42	112	4	GO:0048665
GeneOntologyBiologicalProcess	lung cell differentiation	SOX9 GATA6 NCOR2 NKX2-1	7.86e-05	42	112	4	GO:0060479
GeneOntologyBiologicalProcess	lung epithelial cell differentiation	SOX9 GATA6 NCOR2 NKX2-1	7.86e-05	42	112	4	GO:0060487
GeneOntologyBiologicalProcess	telencephalon development	USP9X ZIC3 NCOR2 PIANP NKX2-1 GLI3 SCN5A TBR1 PROX1	8.36e-05	332	112	9	GO:0021537
GeneOntologyBiologicalProcess	embryo development	ALX3 SOX9 SOX10 TRIP6 USP9X GATA2 DVL3 GATA6 NKX2-6 CUBN KLF4 AXIN1 ZIC3 MEOX1 CITED2 NCOR2 GLI3 USPL1 SOD1 PROX1	8.59e-05	1437	112	20	GO:0009790
GeneOntologyBiologicalProcess	regulation of miRNA transcription	SOX9 GATA2 GATA6 KLF4 NCOR2	8.94e-05	83	112	5	GO:1902893
GeneOntologyBiologicalProcess	miRNA transcription	SOX9 GATA2 GATA6 KLF4 NCOR2	9.47e-05	84	112	5	GO:0061614
GeneOntologyBiologicalProcess	response to transforming growth factor beta	SOX9 USP9X CD2AP MAP3K1 AXIN1 CITED2 ZFP36L2 NKX2-1 SAP130	1.07e-04	343	112	9	GO:0071559
GeneOntologyBiologicalProcess	male sex differentiation	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 NKX2-1	1.08e-04	199	112	7	GO:0046661
GeneOntologyBiologicalProcess	epithelium development	SOX9 SOX10 CD2AP GATA2 DVL3 GATA6 BCL2 NKX2-6 KLF4 MAP3K1 ZIC3 MEOX1 CITED2 NCOR2 SOX21 NKX2-1 GLI3 RCN3 SOD1 PROX1	1.16e-04	1469	112	20	GO:0060429
GeneOntologyBiologicalProcess	striated muscle tissue development	XIRP1 GATA6 SIK1 POU4F1 NKX2-6 ZIC3 CITED2 SCN5A PROX1	1.22e-04	349	112	9	GO:0014706
GeneOntologyBiologicalProcess	sex differentiation	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 DACH2 NKX2-1 SOD1	1.30e-04	352	112	9	GO:0007548
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	CACNA1A SOX9 XIRP1 ZNF219 GATA2 DVL3 GATA6 KLF4 AXIN1 ZIC3 MEOX1 CITED2 NFATC2 NKX2-1 GLI3 DYRK1B ULK1 TBR1 USPL1 PROX1	1.32e-04	1483	112	20	GO:0048646
GeneOntologyBiologicalProcess	cerebellar cortex morphogenesis	CACNA1A USP9X ULK1 PROX1	1.33e-04	48	112	4	GO:0021696
GeneOntologyBiologicalProcess	glandular epithelial cell differentiation	SOX9 GATA2 GATA6 KLF4 PROX1	1.38e-04	91	112	5	GO:0002067
GeneOntologyBiologicalProcess	cell fate determination	GATA2 GATA6 KLF4 PROX1	1.56e-04	50	112	4	GO:0001709
GeneOntologyBiologicalProcess	ear development	SOX9 GATA2 DVL3 BCL2 ZIC3 GLI3 SOD1 PROX1	1.66e-04	285	112	8	GO:0043583
GeneOntologyBiologicalProcess	club cell differentiation	GATA6 NKX2-1	1.74e-04	4	112	2	GO:0060486
GeneOntologyBiologicalProcess	axon development	CACNA1A USP9X CD2AP NTNG1 POU4F1 BCL2 KLF4 NKX2-1 GLI3 AUTS2 ULK1 TBR1	1.93e-04	642	112	12	GO:0061564
GeneOntologyBiologicalProcess	gonad development	SOX9 ATN1 CD2AP BCL2 SF1 CITED2 NKX2-1 SOD1	1.95e-04	292	112	8	GO:0008406
GeneOntologyBiologicalProcess	ear morphogenesis	SOX9 GATA2 DVL3 ZIC3 SOD1 PROX1	1.96e-04	154	112	6	GO:0042471
GeneOntologyBiologicalProcess	pallium development	USP9X ZIC3 PIANP NKX2-1 GLI3 TBR1 PROX1	2.12e-04	222	112	7	GO:0021543
GeneOntologyBiologicalProcess	muscle tissue development	SOX9 XIRP1 GATA6 SIK1 POU4F1 BCL2 NKX2-6 ZIC3 CITED2 SCN5A PROX1	2.29e-04	558	112	11	GO:0060537
GeneOntologyBiologicalProcess	embryonic organ development	ALX3 SOX9 GATA2 DVL3 NKX2-6 AXIN1 ZIC3 CITED2 GLI3 SOD1 PROX1	2.40e-04	561	112	11	GO:0048568
GeneOntologyBiologicalProcess	regulation of miRNA metabolic process	SOX9 GATA2 GATA6 KLF4 NCOR2	2.47e-04	103	112	5	GO:2000628
GeneOntologyBiologicalProcess	axonogenesis	CACNA1A USP9X CD2AP NTNG1 POU4F1 BCL2 NKX2-1 GLI3 AUTS2 ULK1 TBR1	2.59e-04	566	112	11	GO:0007409
GeneOntologyBiologicalProcess	ventral spinal cord development	SOX1 CACNA1A GATA2 GLI3	2.61e-04	57	112	4	GO:0021517
GeneOntologyBiologicalProcess	respiratory system development	SOX9 GATA6 ZIC3 NCOR2 NKX2-1 GLI3 RCN3 PROX1	2.62e-04	305	112	8	GO:0060541
GeneOntologyBiologicalProcess	circulatory system development	SOX9 XIRP1 RPS6KA2 GATA2 DVL3 GATA6 SIK1 POU4F1 NKX2-6 KLF4 ZIC3 CITED2 NCOR2 NFATC2 GLI3 SCN5A ANKRD17 MMP13 PROX1	2.67e-04	1442	112	19	GO:0072359
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	SOX9 SOX10 GATA2 AXIN1 NCOR2 USF3 SOX21 NFATC2 ZFP36L2 NKX2-1 GLI3 ANKRD17 ULK1 PROX1	2.79e-04	875	112	14	GO:0045596
GeneOntologyBiologicalProcess	positive regulation of chondrocyte differentiation	SOX9 ZNF219 GLI3	2.90e-04	24	112	3	GO:0032332
GeneOntologyBiologicalProcess	skin epidermis development	SOX9 GATA6 BCL2 KLF4 NCOR2 SOX21	2.94e-04	166	112	6	GO:0098773
GeneOntologyBiologicalProcess	stem cell population maintenance	SOX9 GATA2 KLF4 ZIC3 ZFP36L2 SAP130 PROX1	3.15e-04	237	112	7	GO:0019827
GeneOntologyBiologicalProcess	cerebellum morphogenesis	CACNA1A USP9X ULK1 PROX1	3.18e-04	60	112	4	GO:0021587
GeneOntologyBiologicalProcess	atrial cardiac muscle tissue development	GATA6 ZIC3 PROX1	3.29e-04	25	112	3	GO:0003228
GeneOntologyBiologicalProcess	maintenance of cell number	SOX9 GATA2 KLF4 ZIC3 ZFP36L2 SAP130 PROX1	3.57e-04	242	112	7	GO:0098727
GeneOntologyBiologicalProcess	cell differentiation in spinal cord	SOX1 CACNA1A GATA2 GLI3	3.83e-04	63	112	4	GO:0021515
GeneOntologyBiologicalProcess	in utero embryonic development	SOX10 USP9X GATA2 GATA6 CUBN KLF4 AXIN1 CITED2 NCOR2 GLI3 USPL1	4.01e-04	596	112	11	GO:0001701
GeneOntologyBiologicalProcess	negative regulation of apoptotic process	CACNA1A SOX9 SOX10 CD2AP PAK5 GATA2 GATA6 IRF7 POU4F1 BCL2 NKX2-6 KLF4 CITED2 GLI3 CPEB4 SOD1	4.06e-04	1133	112	16	GO:0043066
GeneOntologyBiologicalProcess	hindbrain morphogenesis	CACNA1A USP9X ULK1 PROX1	4.07e-04	64	112	4	GO:0021575
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CACNA1A USP9X CD2AP DVL3 NTNG1 GAS7 POU4F1 BCL2 NKX2-1 GLI3 AUTS2 ULK1 TBR1	4.12e-04	802	112	13	GO:0048812
GeneOntologyBiologicalProcess	negative regulation of transforming growth factor beta1 production	CD2AP GATA6	4.32e-04	6	112	2	GO:0032911
GeneOntologyBiologicalProcess	commitment of neuronal cell to specific neuron type in forebrain	GATA2 TBR1	4.32e-04	6	112	2	GO:0021902
GeneOntologyBiologicalProcess	regulation of forebrain neuron differentiation	GATA2 PROX1	4.32e-04	6	112	2	GO:2000977
GeneOntologyBiologicalProcess	lens morphogenesis in camera-type eye	SOX1 CITED2 PROX1	4.62e-04	28	112	3	GO:0002089
GeneOntologyBiologicalProcess	spinal cord development	SOX1 CACNA1A GATA2 GLI3 PROX1	4.82e-04	119	112	5	GO:0021510
GeneOntologyBiologicalProcess	miRNA metabolic process	SOX9 GATA2 GATA6 KLF4 NCOR2	4.82e-04	119	112	5	GO:0010586
GeneOntologyBiologicalProcess	regulation of neuroblast proliferation	SOX10 GATA2 GLI3 PROX1	4.85e-04	67	112	4	GO:1902692
GeneOntologyBiologicalProcess	regulation of neuron differentiation	SOX9 ATN1 GATA2 BCL2 SOX21 GLI3 PROX1	4.89e-04	255	112	7	GO:0045664
GeneOntologyBiologicalProcess	embryonic morphogenesis	ALX3 SOX9 GATA2 DVL3 GATA6 KLF4 AXIN1 ZIC3 CITED2 GLI3 SOD1 PROX1	4.98e-04	713	112	12	GO:0048598
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	SOX9 USP9X MAP3K1 AXIN1 CITED2 ZFP36L2 NKX2-1 SAP130	4.99e-04	336	112	8	GO:0071560
GeneOntologyBiologicalProcess	organ growth	SOX9 GATA6 BCL2 CITED2 MMP13 SOD1 PROX1	5.01e-04	256	112	7	GO:0035265
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CACNA1A USP9X CD2AP DVL3 NTNG1 GAS7 POU4F1 BCL2 NKX2-1 GLI3 AUTS2 ULK1 TBR1	5.02e-04	819	112	13	GO:0120039
GeneOntologyBiologicalProcess	branching involved in ureteric bud morphogenesis	SOX9 BCL2 CITED2 GLI3	5.13e-04	68	112	4	GO:0001658
GeneOntologyCellularComponent	chromatin	SOX1 ALX3 SOX9 SOX10 DVL3 GATA6 IRF7 POU4F1 NKX2-6 KLF4 ZNF446 MEOX1 CITED2 NCOR2 SOX21 NFATC2 UBR5 NKX2-1 ANKRD17 TNKS1BP1 TBR1 SAP130 PROX1	3.57e-06	1480	113	23	GO:0000785
GeneOntologyCellularComponent	CKM complex	CDK8 MED13	2.87e-04	5	113	2	GO:1990508
GeneOntologyCellularComponent	transcription regulator complex	SOX9 GATA2 GATA6 POU4F1 KLF4 NCOR2 DACH2 NFATC2 NKX2-1 GLI3 MED22	3.88e-04	596	113	11	GO:0005667
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	4.57e-04	28	113	3	GO:0002177
Domain	HMG_box_dom	SOX1 SOX9 SOX10 KMT2C SOX21 HMGXB3 PROX1	1.21e-07	65	112	7	IPR009071
Domain	AUTS2	FBRS FBRSL1 AUTS2	2.10e-07	3	112	3	IPR023246
Domain	HMG_box	SOX1 SOX9 SOX10 KMT2C SOX21 HMGXB3	7.42e-07	53	112	6	PF00505
Domain	HMG	SOX1 SOX9 SOX10 KMT2C SOX21 HMGXB3	8.30e-07	54	112	6	SM00398
Domain	HMG_BOX_2	SOX1 SOX9 SOX10 SOX21 HMGXB3	1.77e-05	54	112	5	PS50118
Domain	-	SOX1 SOX9 SOX10 SOX21 HMGXB3	1.94e-05	55	112	5	1.10.30.10
Domain	SH3_9	CD2AP GAS7 RIMBP3 RIMBP3C RIMBP3B	1.06e-04	78	112	5	PF14604
Domain	Sox_N	SOX9 SOX10	1.07e-04	3	112	2	IPR022151
Domain	Sox_N	SOX9 SOX10	1.07e-04	3	112	2	PF12444
Domain	SOXp	SOX1 SOX21	3.52e-04	5	112	2	PF12336
Domain	SOX_fam	SOX1 SOX21	3.52e-04	5	112	2	IPR022097
Domain	DIX	DVL3 AXIN1	7.34e-04	7	112	2	PF00778
Domain	DIX	DVL3 AXIN1	7.34e-04	7	112	2	IPR001158
Domain	DIX	DVL3 AXIN1	7.34e-04	7	112	2	PS50841
Domain	DAX	DVL3 AXIN1	7.34e-04	7	112	2	SM00021
Pathway	WP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION	SOX9 MAP3K1 AXIN1	1.35e-04	17	85	3	M39907
Pathway	WP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION	SOX9 SOX10 GATA6 KLF4 TBR1 FUT4	1.44e-04	132	85	6	M48110
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	CDK8 KLF4 NCOR2 MED22 MED13	1.50e-04	84	85	5	M1008
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	DVL3 SSPOP AXIN1	1.62e-04	18	85	3	M31
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	CDK8 SOX9 ELOA2 ARID3A USP9X GATA2 POU4F1 KLF4 ZNF446 AXIN1 CITED2 KMT2C NCOR2 NFATC2 GLI3 ZNF589 AUTS2 TNKS1BP1 MMP13 MED13	1.71e-04	1387	85	20	M734
Pathway	WP_WNT_SIGNALING_WP363	SOX1 DVL3 AXIN1 NFATC2	2.48e-04	51	85	4	M39721
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	SOX1 CDK8 ALX3 SOX9 SOX10 RPS6KA2 PAK5 GATA2 GATA6 BCL2 KLF4 ZIC3 KMT2C NCOR2 ZFP36L2 MED22 SCN5A CLTB TNKS1BP1 MED13	2.62e-04	1432	85	20	M509
Pathway	WP_MESODERMAL_COMMITMENT_PATHWAY	GATA6 KLF4 AXIN1 ZIC3 SOX21 UBR5	3.20e-04	153	85	6	M39546
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SOX9 SOX10 ZNF219 ARID3A GATA2 GATA6 DIDO1 KLF4 SF1 MEOX1 CITED2 KMT2C ST6GAL2 IBTK SOX21 NFATC2 NKX2-1 GLI3 HMGXB3 PROX1	2.25e-13	709	115	20	22988430
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX1 ALX3 SOX9 SOX10 GATA2 GATA6 IRF7 POU4F1 NKX2-6 KLF4 MEOX1 USF3 SOX21 DACH2 NFATC2 ZFP36L2 NKX2-1 GLI3 TBR1 PROX1	1.98e-11	908	115	20	19274049
Pubmed	Human transcription factor protein interaction networks.	SOX9 SOX10 ARID3A ATN1 PITRM1 TRIP6 USP9X FBRS GATA2 FBRSL1 GATA6 DIDO1 PROSER1 KLF4 ZIC3 KMT2C NCOR2 SMG7 GLI3 AUTS2 ANKRD17 TBR1 SAP130	2.65e-10	1429	115	23	35140242
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX1 ZNF219 ARID3A TRIP6 GATA2 GATA6 DIDO1 KLF4 ZNF446 SF1 CITED2 IBTK SOX21 ZFP36L2 NKX2-1 GLI3 HMGXB3	1.48e-09	808	115	17	20412781
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	SOX9 ZNF219 ARID3A GATA2 GATA6 MEOX1 NCOR2 GLI3 PROX1	1.60e-08	191	115	9	24146773
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ALX3 SOX9 SOX10 GATA2 GATA6 IRF7 POU4F1 KLF4 ZIC3 MEOX1 NFATC2 GLI3 PROX1	3.32e-08	544	115	13	28473536
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ALX3 SOX9 ZNF219 ELOA2 GATA2 GATA6 IRF7 POU4F1 ZNF446 MEOX1 NCOR2 DACH2 NKX2-1 GLI3 HMGXB3 PROX1	3.41e-08	877	115	16	20211142
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ATN1 FBRS FBRSL1 PROSER1 SF1 NCOR2 AUTS2 DTX2	4.41e-08	152	115	8	38360978
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.41e-07	4	115	3	19091768
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CDK8 ZNF219 ATN1 TRIP6 FBRS FBRSL1 GAS7 NCOR2 SMG7 UBR5 GLI3 ZNF589 CPEB4 SCN5A ANKRD17 SAP130 PROX1	1.63e-07	1116	115	17	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PITRM1 FBRSL1 DIDO1 KMT2C ST6GAL2 IBTK SMG7 AUTS2 ANKRD17 HMGXB3 TNKS1BP1 MED13	2.02e-07	529	115	12	14621295
Pubmed	Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh.	SOX1 SOX9 NKX2-1 GLI3	2.61e-07	17	115	4	23444355
Pubmed	Spatio-temporal expression of Sox genes in murine palatogenesis.	SOX1 SOX9 SOX10 SOX21	2.61e-07	17	115	4	27241892
Pubmed	Expression of Sox genes in tooth development.	SOX1 SOX9 SOX10 SOX21	3.35e-07	18	115	4	26864488
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	3.50e-07	5	115	3	17855024
Pubmed	Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.	SOX9 SOX10 POU4F1 SF1	6.50e-07	21	115	4	23300469
Pubmed	Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors.	SOX9 SF1 FUT4	6.99e-07	6	115	3	20736371
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARID3A RPS6KA2 FBRS GATA2 FBRSL1 PAPLN KLF4 KMT2C NCOR2 ZFP36L2 SCN5A HMGXB3 TNKS1BP1 DTX2 ULK1 MED13	7.61e-07	1105	115	16	35748872
Pubmed	Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.	SOX9 SOX10 MEOX1 CITED2	7.92e-07	22	115	4	15162501
Pubmed	Ets1 is required for proper migration and differentiation of the cardiac neural crest.	SOX9 SOX10 GATA6 MEOX1	7.92e-07	22	115	4	20356956
Pubmed	Developmental lung expression and transcriptional regulation of claudin-6 by TTF-1, Gata-6, and FoxA2.	SOX9 GATA6 NKX2-1	1.22e-06	7	115	3	24970044
Pubmed	Tagging genes with cassette-exchange sites.	CDC42BPG USP9X NTNG1 DIDO1 SIK1 KMT2C NCOR2 SAFB TNS1	1.84e-06	335	115	9	15741177
Pubmed	Mutations in MAP3K1 tilt the balance from SOX9/FGF9 to WNT/β-catenin signaling.	SOX9 MAP3K1 AXIN1	1.95e-06	8	115	3	24135036
Pubmed	Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme.	SOX1 SOX9 SOX10	1.95e-06	8	115	3	24198279
Pubmed	Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15.	SOX1 SOX21 GLI3 PROX1	2.91e-06	30	115	4	28560839
Pubmed	Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling.	SOX9 SOX10 NKX2-1 GLI3	2.91e-06	30	115	4	16368932
Pubmed	MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.	DVL3 MAP3K1 AXIN1	2.92e-06	9	115	3	20128690
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CD2AP FBRS GATA6 PTPN23 DIDO1 SEC31A CUBN KLF4 KMT2C ANKRD17 HMGXB3 BOD1L1 DTX2 TNS1 SOD1	3.02e-06	1084	115	15	11544199
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	ATN1 TRIP6 FBRS KMT2C NCOR2 SMG7 AUTS2 ANKRD17 DTX2 SAP130	3.03e-06	457	115	10	32344865
Pubmed	SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch.	SOX1 SOX9 SOX10 SOX21	3.33e-06	31	115	4	19723505
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A ZNF219 USP9X RPS6KA2 PAK5 IQSEC2 DIDO1 SEC31A NCOR2 UBR5 ANKRD17 TNS1 FERMT3 PROX1	3.78e-06	963	115	14	28671696
Pubmed	From head to toes: the multiple facets of Sox proteins.	SOX1 SOX9 SOX10	4.16e-06	10	115	3	10037800
Pubmed	Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti.	SOX9 SOX10 PROX1	4.16e-06	10	115	3	19748502
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TRIP6 USP9X FBRS FBRSL1 RIMBP3 TBC1D8 NCOR2 SMG7 UBR5 TNKS1BP1 CDCA4	4.28e-06	588	115	11	38580884
Pubmed	Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.	SOX1 SOX9 GATA2 POU4F1	4.31e-06	33	115	4	25179941
Pubmed	Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo.	ALX3 SOX9 SOX10 GLI3	4.87e-06	34	115	4	12086465
Pubmed	The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX.	SOX1 SOX9 PROX1	5.70e-06	11	115	3	36067402
Pubmed	Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.	SSPOP NKX2-1 TBR1 PROX1	6.16e-06	36	115	4	18094027
Pubmed	Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome.	GATA6 KLF4 NCOR2 NKX2-1	6.89e-06	37	115	4	22001906
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	ARID3A USP9X DIDO1 ZIC3 NCOR2 IBTK SOX21 UBR5 SAP130	7.14e-06	396	115	9	26687479
Pubmed	Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators.	SOX1 SOX9 SOX10	7.58e-06	12	115	3	11071752
Pubmed	An AUTS2-Polycomb complex activates gene expression in the CNS.	ATN1 FBRS PPP1R8 AUTS2	7.68e-06	38	115	4	25519132
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TRIP6 USP9X IQSEC2 FBRS DVL3 FBRSL1 SIK1 SEC31A MAP3K1 AXIN1 SMG7 UBR5 ZFP36L2 TNKS1BP1	8.85e-06	1038	115	14	26673895
Pubmed	Seven new members of the Sox gene family expressed during mouse development.	SOX1 SOX9 SOX10	9.83e-06	13	115	3	8441686
Pubmed	Stabilization of Epithelial β-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis.	SOX9 SOX10 DACH2	9.83e-06	13	115	3	38159590
Pubmed	CDK8 is a positive regulator of transcriptional elongation within the serum response network.	CDK8 MED22 MED13	9.83e-06	13	115	3	20098423
Pubmed	VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance.	GATA2 KLF4 PROX1	9.83e-06	13	115	3	31461654
Pubmed	MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.	CDK8 GATA2 MED13	9.83e-06	13	115	3	27570068
Pubmed	Post-transcriptional regulation in cranial neural crest cells expands developmental potential.	SOX1 SOX9 SOX10	9.83e-06	13	115	3	36724256
Pubmed	Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.	SOX1 NKX2-1	1.08e-05	2	115	2	35848993
Pubmed	AKT-mediated phosphorylation of Sox9 induces Sox10 transcription in a murine model of HER2-positive breast cancer.	SOX9 SOX10	1.08e-05	2	115	2	33985544
Pubmed	Overproduction of Cu/Zn-superoxide dismutase or Bcl-2 prevents the brain mitochondrial respiratory dysfunction induced by glutathione depletion.	BCL2 SOD1	1.08e-05	2	115	2	10415149
Pubmed	Characterization of the interactions of human ZIC3 mutants with GLI3.	ZIC3 GLI3	1.08e-05	2	115	2	17764085
Pubmed	Dysregulated expression of GATA2 and GATA6 transcription factors in adenomyosis: implications for impaired endometrial receptivity.	GATA2 GATA6	1.08e-05	2	115	2	37972693
Pubmed	Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.	SOX9 SOX10	1.08e-05	2	115	2	25629959
Pubmed	Expression of SOX9 and SOX10 in central neuroepithelial tumor.	SOX9 SOX10	1.08e-05	2	115	2	16791471
Pubmed	Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.	NFATC2 SCN5A	1.08e-05	2	115	2	32778883
Pubmed	Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis.	GATA2 GATA6	1.08e-05	2	115	2	24603652
Pubmed	Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1.	BCL2 SOD1	1.08e-05	2	115	2	16790527
Pubmed	ZNF219 protects human lens epithelial cells against H2O2-induced injury via targeting SOX9 through activating AKT/GSK3β pathway.	SOX9 ZNF219	1.08e-05	2	115	2	34167360
Pubmed	Disruption of GLI3-ZIC3 interaction in the cadmium-induced omphalocele chick model.	ZIC3 GLI3	1.08e-05	2	115	2	21069353
Pubmed	Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.	SOX9 SOX10	1.08e-05	2	115	2	15896776
Pubmed	ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.	BCL2 SOD1	1.08e-05	2	115	2	20460269
Pubmed	Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery.	AXIN1 UBR5	1.08e-05	2	115	2	36224534
Pubmed	Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria.	BCL2 SOD1	1.08e-05	2	115	2	15233914
Pubmed	Brn3a target gene recognition in embryonic sensory neurons.	SOX10 POU4F1	1.08e-05	2	115	2	17196582
Pubmed	Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling.	MAP3K1 AXIN1	1.08e-05	2	115	2	10575011
Pubmed	Aberrant GATA2 epigenetic dysregulation induces a GATA2/GATA6 switch in human gastric cancer.	GATA2 GATA6	1.08e-05	2	115	2	29106391
Pubmed	CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer.	CITED2 NCOR2	1.08e-05	2	115	2	19904269
Pubmed	Dentate gyrus development requires a cortical hem-derived astrocytic scaffold.	SOX1 SOX9 PROX1	1.25e-05	14	115	3	33393905
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	1.25e-05	14	115	3	17662146
Pubmed	Developmental diversification of cortical inhibitory interneurons.	SOX9 CITED2 SOX21 NKX2-1 PROX1	1.34e-05	91	115	5	29513653
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TRIP6 USP9X CD2AP PTPN23 DIDO1 KMT2C SMG7 TNKS1BP1 BOD1L1 SAP130	1.50e-05	549	115	10	38280479
Pubmed	Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.	SOX1 SOX9 SOX10	1.56e-05	15	115	3	15893981
Pubmed	Loss of Axin2 Causes Ocular Defects During Mouse Eye Development.	SOX9 POU4F1 PROX1	1.56e-05	15	115	3	27701636
Pubmed	Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes.	SOX1 SOX9 SOX10	1.91e-05	16	115	3	24257626
Pubmed	New semidominant mutations that affect mouse development.	SOX9 SOX10 ZIC3	1.91e-05	16	115	3	15384171
Pubmed	Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence.	SOX9 POU4F1 PROX1	1.91e-05	16	115	3	24125957
Pubmed	A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.	SOX9 SOX10 GLI3	1.91e-05	16	115	3	38713624
Pubmed	Interaction network of human early embryonic transcription factors.	ARID3A ATN1 FBRS FBRSL1 PROSER1 KMT2C NCOR2 AUTS2	2.30e-05	351	115	8	38297188
Pubmed	MicroRNA-140 plays dual roles in both cartilage development and homeostasis.	SOX9 MEOX1 MMP13	2.32e-05	17	115	3	20466812
Pubmed	Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice.	SOX1 NKX2-1 GLI3	2.32e-05	17	115	3	28778798
Pubmed	FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart.	SOX9 GATA6 MEOX1	2.32e-05	17	115	3	17274974
Pubmed	NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.	POU4F1 AUTS2 TBR1	2.32e-05	17	115	3	34637754
Pubmed	The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina.	SOX9 POU4F1 PROX1	2.32e-05	17	115	3	25501893
Pubmed	Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.	SOX9 SOX10 CITED2	2.32e-05	17	115	3	18330926
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	MSRB2 KMT2C UBR5 BOD1L1	2.32e-05	50	115	4	37974198
Pubmed	NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis.	SOX9 TBR1 PROX1	2.77e-05	18	115	3	23042739
Pubmed	Sex-dependent expression of TRPV1 in bladder arterioles.	SOX9 SOX21 NKX2-1	2.77e-05	18	115	3	27654891
Pubmed	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.	ATN1 NKX2-1 GLI3	2.77e-05	18	115	3	14645126
Pubmed	Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development.	SOX9 GATA6 GLI3	2.77e-05	18	115	3	27352137
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	ALX3 SOX9 SOX10 TRIP6 NKX2-6 MEOX1 PROX1	2.85e-05	263	115	7	20932939
Pubmed	A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis.	ALX3 SOX9 SOX10 GLI3	2.93e-05	53	115	4	38466355
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	TENT4A NTNG1 KMT2C ST6GAL2 AUTS2 TNS1 MN1	3.00e-05	265	115	7	19240061
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CDK8 ATN1 FBRS KLF4 MED22 SAP130 MED13	3.22e-05	268	115	7	33640491
Pubmed	Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells.	SOX1 BCL2	3.24e-05	3	115	2	18437159
Pubmed	Rare genetic variants in GATA transcription factors in patients with hypertrophic cardiomyopathy.	GATA2 GATA6	3.24e-05	3	115	2	28381408
Pubmed	Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.	ZIC3 GLI3	3.24e-05	3	115	2	22234993
Pubmed	Differential expression of epithelial–mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer.	SOX9 SOX10	3.24e-05	3	115	2	26467042
Pubmed	The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors.	GATA6 NKX2-1	3.24e-05	3	115	2	21126317
Interaction	NFIC interactions	SOX9 SOX10 ARID3A FBRS GATA2 FBRSL1 NCOR2 NKX2-1 DTX2 TBR1 SAP130	2.78e-08	210	113	11	int:NFIC
Interaction	BCL9 interactions	SOX9 SOX10 USP9X GATA2 KLF4 SMG7 DTX2 TBR1	2.81e-08	86	113	8	int:BCL9
Interaction	NCOA3 interactions	SOX9 SOX10 ZNF219 GATA2 KLF4 NCOR2 SMG7 NKX2-1 DTX2 TBR1 MN1	5.39e-08	224	113	11	int:NCOA3
Interaction	EYA4 interactions	ATN1 TRIP6 FBRS GATA2 DVL3 FBRSL1 PROSER1 SF1 NCOR2 AUTS2 DTX2	1.23e-07	243	113	11	int:EYA4
Interaction	TLE3 interactions	SOX9 ATN1 FBRS GATA2 FBRSL1 PROSER1 NCOR2 SMG7 UBR5 AUTS2 TNKS1BP1 TBR1 SAP130	1.93e-07	376	113	13	int:TLE3
Interaction	PIN1 interactions	ATN1 TRIP6 DIDO1 SIK1 BCL2 ZNF446 SF1 ZNF783 AXIN1 MEOX1 NCOR2 NFATC2 SOD1	2.38e-07	383	113	13	int:PIN1
Interaction	TBXT interactions	ARID3A ATN1 FBRS FBRSL1 KMT2C NCOR2 TBR1 SAP130	2.92e-07	116	113	8	int:TBXT
Interaction	FANCD2OS interactions	FBRS FBRSL1 DYRK1B AUTS2 TNKS1BP1	3.04e-07	26	113	5	int:FANCD2OS
Interaction	PAX9 interactions	ATN1 FBRS FBRSL1 PROSER1 KLF4 KMT2C NCOR2 SAP130	7.00e-07	130	113	8	int:PAX9
Interaction	CREBBP interactions	CDK8 SOX9 RPS6KA2 GATA2 IRF7 KLF4 CITED2 PPP1R8 NCOR2 SMG7 NFATC2 NKX2-1 GLI3 DYRK1B PROX1	1.29e-06	599	113	15	int:CREBBP
Interaction	NFIB interactions	SOX10 ARID3A FBRS GATA2 KMT2C NCOR2 DTX2 TBR1	1.37e-06	142	113	8	int:NFIB
Interaction	ZNF609 interactions	SOX9 SOX10 ATN1 GATA2 SMG7 AUTS2 DTX2 TBR1	1.69e-06	146	113	8	int:ZNF609
Interaction	CTBP1 interactions	ZNF219 FBRS DVL3 FBRSL1 SEC31A KLF4 SF1 NCOR2 NFATC2 NKX2-1 DYRK1B DTX2	3.01e-06	406	113	12	int:CTBP1
Interaction	KDM6A interactions	SOX9 SOX10 GATA2 PROSER1 KLF4 KMT2C BOD1L1 TBR1	3.67e-06	162	113	8	int:KDM6A
Interaction	TNRC6A interactions	KMT2C SMG7 UBR5 GLI3 CPEB4 CLTB ANKRD17 TNKS1BP1 DTX2 MED13	4.03e-06	280	113	10	int:TNRC6A
Interaction	CEP85 interactions	CEP128 MAP3K1 SMG7 GLI3 CPEB4 ANKRD17 TNKS1BP1 DTX2	5.02e-06	169	113	8	int:CEP85
Interaction	KMT2D interactions	SOX9 SOX10 GATA2 KLF4 KMT2C SMG7 BOD1L1 TBR1	5.02e-06	169	113	8	int:KMT2D
Interaction	EGR2 interactions	SOX10 ARID3A ATN1 FBRS FBRSL1 PROSER1 KMT2C NCOR2	5.48e-06	171	113	8	int:EGR2
Interaction	TLX1 interactions	ARID3A ATN1 FBRS FBRSL1 KMT2C NCOR2 AUTS2 SAP130	6.49e-06	175	113	8	int:TLX1
Interaction	BCOR interactions	RPS6KA2 FBRS GATA2 FBRSL1 NCOR2 IBTK SMG7 GLI3 DTX2 TBR1	7.84e-06	302	113	10	int:BCOR
Interaction	SP7 interactions	ARID3A ATN1 PITRM1 FBRS FBRSL1 PROSER1 KMT2C NCOR2 TBR1 SAP130	8.30e-06	304	113	10	int:SP7
Interaction	PRR12 interactions	SOX9 GATA2 SMG7 DTX2 TBR1 SOD1	1.01e-05	88	113	6	int:PRR12
Interaction	HIVEP1 interactions	CDK8 CACNA1A SOX10 GATA2 KLF4 SMG7 TBR1 SOD1	1.01e-05	186	113	8	int:HIVEP1
Interaction	KMT2C interactions	SOX9 ATN1 GATA2 KLF4 KMT2C BOD1L1 TBR1	1.06e-05	134	113	7	int:KMT2C
Interaction	SMAD2 interactions	CDK8 SOX9 USP9X IRF7 AXIN1 CITED2 KMT2C UBR5 GLI3 MED22 SOD1	1.09e-05	385	113	11	int:SMAD2
Interaction	NFIA interactions	SOX9 SOX10 ARID3A GATA2 KLF4 NCOR2 DTX2 TBR1	1.10e-05	188	113	8	int:NFIA
Interaction	HNF1B interactions	SOX9 SOX10 ARID3A PROSER1 KMT2C NCOR2 TBR1 SAP130	1.18e-05	190	113	8	int:HNF1B
Interaction	ZNF608 interactions	SOX10 ATN1 GATA2 SMG7 AUTS2 TBR1	1.39e-05	93	113	6	int:ZNF608
Interaction	ARID4B interactions	CDK8 SOX9 SOX10 ZNF219 USP9X GATA2 TBR1 SAP130	1.66e-05	199	113	8	int:ARID4B
Interaction	NCOA6 interactions	SOX9 GATA2 SF1 KMT2C NCOR2 SMG7 BOD1L1	1.76e-05	145	113	7	int:NCOA6
Interaction	RING1 interactions	FBRS GATA2 FBRSL1 KMT2C SMG7 UBR5 AUTS2 MN1	1.78e-05	201	113	8	int:RING1
Interaction	HIPK2 interactions	DVL3 POU4F1 MAP3K1 AXIN1 NKX2-1 DYRK1B	1.88e-05	98	113	6	int:HIPK2
Interaction	NUP35 interactions	ATN1 TRIP6 FBRS KMT2C NCOR2 SMG7 NKX2-1 AUTS2 ANKRD17 DTX2 SAP130	2.67e-05	424	113	11	int:NUP35
Interaction	MED19 interactions	CDK8 TRIP6 UBR5 MED22 DTX2 MED13	2.94e-05	106	113	6	int:MED19
Interaction	TNRC6B interactions	FBRS PTPN23 CEP128 SMG7 GLI3 CPEB4 CLTB ANKRD17 TNKS1BP1	3.04e-05	282	113	9	int:TNRC6B
Interaction	KDM2B interactions	SOX9 FBRS GATA2 KLF4 SMG7 GLI3 TBR1	3.46e-05	161	113	7	int:KDM2B
Interaction	ERG interactions	SOX10 ARID3A USP9X FBRS FBRSL1 KMT2C NCOR2 UBR5	3.74e-05	223	113	8	int:ERG
Interaction	PAX6 interactions	SOX9 SOX10 ARID3A FBRS FBRSL1 KMT2C NCOR2 SAP130 SOD1 PROX1	4.08e-05	366	113	10	int:PAX6
Interaction	TBR1 interactions	FBRS FBRSL1 PROSER1 KMT2C NCOR2 TBR1	4.22e-05	113	113	6	int:TBR1
Interaction	NFIX interactions	SOX9 SOX10 ARID3A KMT2C NCOR2 DTX2 TBR1 SAP130	4.25e-05	227	113	8	int:NFIX
Interaction	DCAF7 interactions	SOX10 FBRS GATA2 FBRSL1 SIK1 SEC31A MAP3K1 NFATC2 DYRK1B AUTS2	4.27e-05	368	113	10	int:DCAF7
Interaction	TOP3B interactions	ARID3A RPS6KA2 FBRS GATA2 FBRSL1 PAPLN KLF4 KMT2C NCOR2 IBTK SAFB SMG7 ZFP36L2 CPEB4 SCN5A ANKRD17 HMGXB3 TNKS1BP1 DTX2 ULK1 MED13	6.09e-05	1470	113	21	int:TOP3B
Interaction	PAX7 interactions	ARID3A FBRS FBRSL1 KMT2C NCOR2 SAP130	7.10e-05	124	113	6	int:PAX7
Interaction	CRX interactions	SOX10 ARID3A ATN1 FBRS FBRSL1 PROSER1 KMT2C NCOR2	9.34e-05	254	113	8	int:CRX
Interaction	RCOR1 interactions	CD2AP FBRS GATA2 DVL3 KLF4 NCOR2 NFATC2 UBR5 NKX2-1 ANKRD17 TNKS1BP1	1.05e-04	494	113	11	int:RCOR1
Interaction	POU5F1 interactions	SOX10 ZNF219 USP9X CUBN KLF4 ZIC3 NCOR2 IBTK SOX21 UBR5 ANKRD17 SAP130	1.08e-04	584	113	12	int:POU5F1
Interaction	IRF4 interactions	FBRS KMT2C NCOR2 NFATC2 PROX1	1.16e-04	85	113	5	int:IRF4
Interaction	PRRC2B interactions	ATN1 CD2AP GATA2 SF1 SMG7 GLI3 CPEB4 ANKRD17	1.25e-04	265	113	8	int:PRRC2B
Interaction	GSC interactions	ATN1 FBRS KMT2C NCOR2 AUTS2	1.30e-04	87	113	5	int:GSC
Interaction	GATA2 interactions	ARID3A FBRS GATA2 FBRSL1 KMT2C NCOR2 SAP130	1.32e-04	199	113	7	int:GATA2
Interaction	CAPN13 interactions	DIDO1 SF1 SAFB	1.56e-04	19	113	3	int:CAPN13
Interaction	SOX10 interactions	SOX9 SOX10 PROSER1 MEOX1 NCOR2	1.69e-04	92	113	5	int:SOX10
Interaction	FOXI1 interactions	FBRS FBRSL1 KMT2C NCOR2 DTX2	1.69e-04	92	113	5	int:FOXI1
Interaction	PCGF1 interactions	SOX10 USP9X FBRS GATA2 DIDO1 IBTK TBR1	1.73e-04	208	113	7	int:PCGF1
Interaction	DPF1 interactions	SOX9 SOX10 GATA2 KLF4 TBR1	1.97e-04	95	113	5	int:DPF1
Interaction	TLE1 interactions	SOX9 SOX10 ATN1 GATA2 KLF4 SMG7 TBR1	2.00e-04	213	113	7	int:TLE1
Interaction	TP53BP1 interactions	CDK8 ALX3 ARID3A PPP1R8 SAFB NFATC2 UBR5 MED22 USPL1 SAP130 MED13	2.04e-04	533	113	11	int:TP53BP1
Interaction	KDM1A interactions	USP9X TEDC2 CD2AP FBRS GATA2 DVL3 NCOR2 SMG7 NFATC2 UBR5 NKX2-1 ANKRD17 TNKS1BP1 PROX1 CDCA4	2.45e-04	941	113	15	int:KDM1A
Interaction	ODF2 interactions	TRIP6 DVL3 CEP128 MAP3K1 IBTK SMG7	2.67e-04	158	113	6	int:ODF2
Interaction	EP300 interactions	SOX9 SOX10 TENT4A USP9X GATA2 GATA6 IRF7 SEC31A KLF4 SF1 CITED2 NCOR2 SAFB NFATC2 DYRK1B AUTS2 TBR1 MN1 PROX1	2.80e-04	1401	113	19	int:EP300
Interaction	ZNF503 interactions	ATN1 GATA2 DTX2 TBR1	2.94e-04	57	113	4	int:ZNF503
Interaction	KLF3 interactions	ARID3A PITRM1 FBRS DVL3 FBRSL1 NCOR2 SAP130	3.03e-04	228	113	7	int:KLF3
Interaction	YTHDF1 interactions	RPS6KA2 CEP128 SF1 SMG7 GLI3 CPEB4 PRR32 ANKRD17	3.04e-04	302	113	8	int:YTHDF1
Interaction	NANOG interactions	ZNF219 ARID3A USP9X DIDO1 ZIC3 KMT2C NCOR2 IBTK SOX21 SAP130	3.78e-04	481	113	10	int:NANOG
Interaction	PAX8 interactions	FBRSL1 PROSER1 KMT2C NCOR2 NKX2-1	4.05e-04	111	113	5	int:PAX8
Interaction	PRR32 interactions	PRR32 DTX2	4.61e-04	6	113	2	int:PRR32
Interaction	LDB1 interactions	SOX10 GATA2 ZNF446 DTX2 TBR1	4.77e-04	115	113	5	int:LDB1
Interaction	RUNX1 interactions	ARID3A GATA2 SF1 NCOR2 NFATC2 NKX2-1 DTX2 FERMT3	4.85e-04	324	113	8	int:RUNX1
Interaction	ARID1B interactions	SOX9 SOX10 GATA2 KLF4 SMG7 TBR1	4.90e-04	177	113	6	int:ARID1B
Interaction	ZNF750 interactions	KLF4 UBR5 TNKS1BP1	5.08e-04	28	113	3	int:ZNF750
Interaction	AURKA interactions	CDK8 PITRM1 TRIP6 USP9X PAK5 PTPN23 KLF4 CEP128 NCOR2 SAFB UBR5 TNKS1BP1	5.35e-04	696	113	12	int:AURKA
Interaction	ALG13 interactions	ATN1 FBRS SF1 NCOR2 SMG7 CPEB4	5.84e-04	183	113	6	int:ALG13
Interaction	WWTR1 interactions	TRIP6 CD2AP DVL3 PTPN23 DIDO1 SMG7 NKX2-1 TNKS1BP1 DTX2	6.23e-04	422	113	9	int:WWTR1
Interaction	FRS3 interactions	TRIP6 CD2AP ZNF446 RIMBP3C TNS1	6.24e-04	122	113	5	int:FRS3
Interaction	SSPOP interactions	ATN1 SSPOP	6.43e-04	7	113	2	int:SSPOP
Interaction	TAF1 interactions	CDK8 ATN1 FBRS FBRSL1 UBR5 GLI3 CPEB4	6.63e-04	260	113	7	int:TAF1
Interaction	FAM193A interactions	IBTK SMG7 CPEB4 ANKRD17	6.82e-04	71	113	4	int:FAM193A
Interaction	PROSER1 interactions	SOX10 PROSER1 TBR1	6.88e-04	31	113	3	int:PROSER1
Interaction	DGCR6L interactions	ATN1 ZNF446 RIMBP3	6.88e-04	31	113	3	int:DGCR6L
Interaction	CEP44 interactions	TRIP6 DVL3 CEP128 IBTK SMG7 GLI3	6.92e-04	189	113	6	int:CEP44
Interaction	MBP interactions	CDK8 ATN1 MAP3K1 DYRK1B ULK1	7.22e-04	126	113	5	int:MBP
Interaction	NCOR2 interactions	SOX10 GATA2 SF1 NCOR2 SMG7 DTX2 TBR1	7.25e-04	264	113	7	int:NCOR2
Interaction	PML interactions	ARID3A CD2AP PAK5 GATA2 DVL3 IRF7 BCL2 SF1 AXIN1 NCOR2 SAFB UBR5 TNKS1BP1 SAP130	7.27e-04	933	113	14	int:PML
Interaction	SMARCA2 interactions	CDK8 SOX9 SOX10 GATA2 KLF4 CPEB4 SCN5A TBR1	7.46e-04	346	113	8	int:SMARCA2
GeneFamily	SRY-boxes	SOX1 SOX9 SOX10 SOX21	8.56e-07	19	72	4	757
GeneFamily	Cyclins\|Mediator complex	CDK8 MED22 MED13	3.03e-04	33	72	3	1061
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA2 GATA6	1.59e-03	15	72	2	82
Coexpression	BENPORATH_SUZ12_TARGETS	SOX1 ALX3 CACNA1A SOX9 SOX10 GATA2 GATA6 GAS7 POU4F1 BCL2 GPR88 KLF4 ADCY8 RIMBP3 SOX21 DACH2 NKX2-1 RIMBP3C TBR1 FUT4 RIMBP3B	3.61e-09	1035	114	21	M9898
Coexpression	BENPORATH_PRC2_TARGETS	ALX3 GATA2 GATA6 POU4F1 BCL2 GPR88 KLF4 ADCY8 RIMBP3 DACH2 NKX2-1 RIMBP3C TBR1 FUT4 RIMBP3B	1.52e-07	650	114	15	M8448
Coexpression	BENPORATH_ES_WITH_H3K27ME3	ALX3 IL10RA CACNA1A SOX9 RPS6KA2 GATA2 GATA6 POU4F1 BCL2 GPR88 KLF4 ADCY8 RIMBP3 DACH2 NKX2-1 RIMBP3C TBR1 FUT4 RIMBP3B	3.33e-07	1115	114	19	M10371
Coexpression	BENPORATH_EED_TARGETS	SOX1 ALX3 GATA2 GATA6 POU4F1 BCL2 GPR88 KLF4 ADCY8 RIMBP3 SOX21 DACH2 NKX2-1 AUTS2 RIMBP3C TBR1 FUT4 RIMBP3B	7.31e-07	1059	114	18	M7617
Coexpression	GSE3982_DC_VS_NKCELL_DN	DVL3 DIDO1 IRF7 BCL2 MAP3K1 SMG7 ANKRD17 CDCA4	2.46e-06	197	114	8	M5480
Coexpression	GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP	TENT4A DVL3 SIK1 SEC31A TBC1D8 NCOR2 ULK1	2.23e-05	193	114	7	M3303
Coexpression	GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN	TENT4A RPS6KA2 FBRS PTPN23 IRF7 ANKRD17 MMP13	2.80e-05	200	114	7	M8647
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	XIRP1 ELOA2 NCOR2 USF3 CPEB4 DTX2 FUT4 TNS1 MN1 RCN3	2.90e-05	452	114	10	M18685
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	ALX3 CACNA1A SOX9 GATA2 GPR135 GAS7 VWA7 MSRB2 SMG7 DYRK1B DTX2 TNS1 TNXA CDCA4	4.13e-05	909	114	14	M41018
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SOX1 SOX9 GATA2 GATA6 GPR88 KLF4 ZIC3 SOX21 NFATC2 ZFP36L2 GLI3 SCN5A TBR1 FUT4 PROX1	6.55e-05	1074	114	15	M1941
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	CDK8 ARID3A CD2AP IRF7 CEP128 USF3 NFATC2	3.53e-07	174	115	7	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	facs-Skin-nan-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 KLF4 CEP128 MAP3K1 TNS1 MN1 SOD1	7.61e-07	195	115	7	ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	CDK8 ARID3A CD2AP KLF4 CEP128 USF3	6.50e-06	176	115	6	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	ARID3A TENT4A RPS6KA2 CD2AP IRF7 AUTS2	6.72e-06	177	115	6	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX9 PAPLN POU4F1 SOX21 ZFP36L2 GLI3	6.94e-06	178	115	6	4813d6509738f088c12ebf395b70d496af04649a
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SOX9 OGFR USP9X CD2AP IRF7 KMT2C	8.13e-06	183	115	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	CF-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	TENT4A CD2AP BCL2 CEP128 NFATC2 AUTS2	1.13e-05	194	115	6	3feb8a0ba3368673c53e9cbd4980e73d18697718
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A USP9X RPS6KA2 SEC31A KMT2C BOD1L1	1.17e-05	195	115	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A USP9X RPS6KA2 SEC31A KMT2C BOD1L1	1.17e-05	195	115	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	mLN-T_cell-Treg\|T_cell / Region, Cell class and subclass	IL10RA BCL2 MAP3K1 MEOX1 TBC1D8 SOD1	1.24e-05	197	115	6	3779489d57ebda33277c79cba037f4c73128c8ba
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA FBRSL1 SEC31A SF1 ZFP36L2 FERMT3	1.24e-05	197	115	6	e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCell	facs-Brain_Myeloid-Cortex_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA FBRSL1 SEC31A SF1 ZFP36L2 FERMT3	1.24e-05	197	115	6	81379fe6bd14a1ba26f4a159497262adcb600b18
ToppCell	facs-Brain_Myeloid-Cortex_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA FBRSL1 SEC31A SF1 ZFP36L2 FERMT3	1.24e-05	197	115	6	271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA FBRSL1 SEC31A SF1 ZFP36L2 FERMT3	1.24e-05	197	115	6	9db329c6fea532dd1afb624f4c29c92407f45568
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA FBRSL1 SEC31A SF1 ZFP36L2 FERMT3	1.24e-05	197	115	6	173c0c8de4e69882a9f91189deeb4a651fefe551
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	NTNG1 POU4F1 FREM3 ZIC3 PROX1	1.28e-05	116	115	5	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early\|World / Primary Cells by Cluster	ALX3 SOX9 ZNF219 CITED2 ZFP36L2 GLI3	1.31e-05	199	115	6	549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-early-40\|World / Primary Cells by Cluster	ALX3 SOX9 ZNF219 CITED2 ZFP36L2 GLI3	1.31e-05	199	115	6	23625d757173bdd35a51c7919ff4b588168d2553
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX9 USP9X ST6GAL2 ZFP36L2 GLI3 MN1	1.31e-05	199	115	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SIK1 MAP3K1 CITED2 SCN5A PROX1	3.87e-05	146	115	5	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	Mild_COVID-19-Myeloid-TRAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	GPR135 PROSER1 KLF4 DENND4B ULK1	4.99e-05	154	115	5	ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPG PTPN23 DIDO1 BCL2 PIANP	6.53e-05	163	115	5	a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	PTPN23 VWA7 USF3 SMG7 ZNF589	7.12e-05	166	115	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL2 CUBN RIMBP3 ZP1 PROX1	7.12e-05	166	115	5	67370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GATA2 IRF7 KLF4 ZIC3 MEOX1	7.12e-05	166	115	5	27af6c906cff1d40d134f0386db7708869691121
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL2 CUBN RIMBP3 ZP1 PROX1	7.12e-05	166	115	5	7f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA PITRM1 TRIP6 IQSEC2 AUTS2	7.53e-05	168	115	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	368C-Lymphocytic-ILC\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF219 PROSER1 BCL2 CUBN MEOX1	8.19e-05	171	115	5	3b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MAP3K1 CITED2 DACH2 SCN5A PROX1	8.19e-05	171	115	5	5efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCell	368C-Lymphocytic-ILC-ILC-2\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF219 PROSER1 BCL2 CUBN MEOX1	8.19e-05	171	115	5	fd01076574dcc82bfd4a1538812500543b16794f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SIK1 MAP3K1 CITED2 DACH2 PROX1	8.19e-05	171	115	5	f9ae7964a3740f559431125c17c660549798cccc
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPG FBRSL1 AXIN1 TBC1D8 DTX2	9.38e-05	176	115	5	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDC42BPG FBRSL1 AXIN1 TBC1D8 DTX2	9.63e-05	177	115	5	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	BAL-Severe-cDC_3\|Severe / Compartment, Disease Groups and Clusters	GATA2 GPR135 CITED2 USF3 ZFP36L2	9.63e-05	177	115	5	939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RIMBP3 RIMBP3C RIMBP3B MN1 PROX1	9.89e-05	178	115	5	39889db130216655a34796e7030ffeb372465500
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX9 PAPLN BCL2 CUBN ADCY8	1.02e-04	179	115	5	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS7 ST6GAL2 DACH2 NFATC2 AUTS2	1.04e-04	180	115	5	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS7 ST6GAL2 DACH2 NFATC2 AUTS2	1.04e-04	180	115	5	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	droplet-Marrow-BM\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 OGFR IRF7 ZFP36L2 SOD1	1.07e-04	181	115	5	4169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 IRF7 KLF4 TNS1	1.10e-04	182	115	5	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 IRF7 KLF4 TNS1	1.10e-04	182	115	5	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 IRF7 KLF4 TNS1	1.10e-04	182	115	5	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX1 SOX10 GAS7 ZIC3 SOX21	1.16e-04	184	115	5	7712f2e1fae5cdde2d4e355b860dc8536b28e4f6
ToppCell	droplet-Marrow-BM-1m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OGFR IRF7 KLF4 CITED2 DTX2	1.16e-04	184	115	5	69348c9237e44f7752ac01f60e733ad41580fdb8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SOX1 NTNG1 GPR88 RIMBP3C PROX1	1.19e-04	185	115	5	6e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 SOX9 GAS7 MEOX1 RCN3	1.22e-04	186	115	5	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 SOX9 GAS7 MEOX1 RCN3	1.22e-04	186	115	5	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GATA2 GATA6 KLF4 TNKS1BP1 FERMT3	1.28e-04	188	115	5	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SIK1 BCL2 SF1 MAP3K1 SOD1	1.28e-04	188	115	5	939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 GATA2 GATA6 CITED2 TBC1D8	1.31e-04	189	115	5	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 VWA7 RIMBP3 CITED2 SOD1	1.31e-04	189	115	5	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 XIRP1 GATA6 SCN5A RCN3	1.31e-04	189	115	5	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 IRF7 KLF4 MEOX1 MN1	1.31e-04	189	115	5	92319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 GATA2 GATA6 CITED2 TBC1D8	1.31e-04	189	115	5	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS7 ST6GAL2 DACH2 NFATC2 AUTS2	1.41e-04	192	115	5	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS7 ST6GAL2 DACH2 NFATC2 AUTS2	1.41e-04	192	115	5	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 SIK1 KLF4 ZIC3	1.44e-04	193	115	5	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 SIK1 KLF4 ZIC3	1.44e-04	193	115	5	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	facs-Marrow-B-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS7 SIK1 KLF4 MAP3K1 MED13	1.44e-04	193	115	5	24c34c6635eb7fc2878282803c421b64320e77d8
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP GATA2 SIK1 KLF4 ZIC3	1.44e-04	193	115	5	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS7 SIK1 KLF4 MAP3K1 MED13	1.48e-04	194	115	5	7ee8ac172c2dee7df7dc4eb222e0985a0089bda8
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 GATA6 GAS7 MN1 RCN3	1.48e-04	194	115	5	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 GATA6 GAS7 MN1 RCN3	1.52e-04	195	115	5	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	droplet-Marrow-BM-1m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 OGFR IRF7 CITED2 ZFP36L2	1.52e-04	195	115	5	637b06ef3967b03f7165d102d316e8b7161a817d
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 GATA6 GAS7 MN1 RCN3	1.52e-04	195	115	5	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Cytl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GATA2 GATA6 IRF7 KLF4	1.53e-04	104	115	4	5d9cd14e53a2f1060e528abf6c0694be9d72c356
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	CACNA1A RPS6KA2 GATA2 KLF4 MEOX1	1.63e-04	198	115	5	3c3a5d2555f6af4aa33f9ea778808315d0e39d86
ToppCell	(00)_Basal-(1)_GFP\|(00)_Basal / shred by cell type by condition	SOX9 GATA6 SIK1 KLF4 CLTB	1.67e-04	199	115	5	105b15157f35df3fdf857e306f11e4e8200e05d4
ToppCell	IPF-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	RPS6KA2 SIK1 BCL2 TBC1D8 TNS1	1.67e-04	199	115	5	3c2b362d5e824e1a04830e70352f8818de984174
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IRF7 NFATC2 ZFP36L2 AUTS2 SOD1	1.67e-04	199	115	5	f3cc3cda38f78d1d12d865df339d93c5fecf19f2
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IRF7 NFATC2 ZFP36L2 AUTS2 SOD1	1.67e-04	199	115	5	c3c73c9404a73133bfad1f9ced292f5e508ef767
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PAK5 ST6GAL2 CPEB4 AUTS2 TBR1	1.71e-04	200	115	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Glia_progenitor_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SOX9 MAP3K1 MEOX1 NFATC2 ZFP36L2	1.71e-04	200	115	5	859f98f63797087e7df18be632de153009b6cab1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Stem_cells\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX1 SOX9 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	474e6ab48f199315f3cca86b81fdf54e0461b7b8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte\|3m / Sample Type, Dataset, Time_group, and Cell type.	SOX9 TRIP6 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	98d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX1 SOX9 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A PAPLN BCL2 ZNF446 AXIN1	1.71e-04	200	115	5	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PAK5 PIANP CPEB4 AUTS2 TBR1	1.71e-04	200	115	5	44bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PAK5 ST6GAL2 CPEB4 AUTS2 TBR1	1.71e-04	200	115	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal-Neurons\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PAK5 ST6GAL2 CPEB4 AUTS2 TBR1	1.71e-04	200	115	5	ddac952ad1d46021c2d17d816de9bc31730a0941
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A PAK5 GAS7 AUTS2 MN1	1.71e-04	200	115	5	5b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX1 SOX9 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	IL10RA IRF7 SF1 ZFP36L2 BOD1L1	1.71e-04	200	115	5	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial\|3m / Sample Type, Dataset, Time_group, and Cell type.	SOX9 TRIP6 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	38b51f337e183011e3ff32997ec26d8a424c6b78
ToppCell	mLN-Dendritic_cell-pDC\|Dendritic_cell / Region, Cell class and subclass	ARID3A IRF7 KMT2C ZFP36L2 ULK1	1.71e-04	200	115	5	10ae1ac8a98346320a92e855aebb3a7109f0ab9b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Stem_cells-Stem_cells\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX1 SOX9 SOX21 ZFP36L2 GLI3	1.71e-04	200	115	5	01a29651e9bb64ef7666c6a61ec396eeb88b2816
Drug	glycidol	ALX3 IL10RA SOX9 CDC42BPG ARID3A IQSEC2 BCL2 NKX2-6 VWA7 KLF4 SSPOP ADCY8 FUT4	5.05e-07	466	112	13	ctd:C004312
Drug	5213008; Down 200; 18uM; MCF7; HT_HG-U133A_EA	ARID3A OGFR RPS6KA2 FBRS GATA2 DVL3 IRF7 ZFP36L2 CLTB	5.30e-07	195	112	9	898_DN
Drug	Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A	SOX10 ATN1 GPR135 POU4F1 KLF4 MAP3K1 ZIC3 SOX21 ZNF589	5.30e-07	195	112	9	6691_UP
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	OGFR TEDC2 RPS6KA2 DIDO1 IRF7 KLF4 CITED2 ZFP36L2 ZNF589	5.53e-07	196	112	9	2974_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ATN1 ZNF446 SF1 NCOR2 SMG7 ZFP36L2 SCN5A CLTB TBR1	5.77e-07	197	112	9	5276_UP
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; PC3; HT_HG-U133A	ELOA2 ATN1 TEDC2 RPS6KA2 GPR135 GAS7 TNS1 RCN3 PROX1	6.02e-07	198	112	9	5108_UP
Drug	ST021200; Down 200; 10uM; MCF7; HT_HG-U133A	SOX9 ZNF219 DVL3 NCOR2 SMG7 ZFP36L2 ZNF589 AUTS2 MMP13	6.02e-07	198	112	9	7554_DN
Drug	Pentetic acid [67-43-6]; Down 200; 10.2uM; PC3; HT_HG-U133A	ZNF219 ATN1 RPS6KA2 IQSEC2 ZNF446 SF1 ZFP36L2 HMGXB3 TNS1	6.02e-07	198	112	9	4669_DN
Drug	Niclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	INHBE GPR88 ZNF446 NCOR2 AUTS2 ULK1 TBR1 MMP13	1.16e-06	158	112	8	4136_UP
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A	INHBE BCL2 KLF4 ZNF783 AXIN1 MSRB2 FUT4 TNS1	5.37e-06	194	112	8	2485_DN
Drug	Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	ALX3 SOX9 RPS6KA2 ZNF446 SF1 ZFP36L2 ZNF589 FUT4	5.57e-06	195	112	8	3478_UP
Drug	Carcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A	INHBE ZNF219 NTNG1 GAS7 BCL2 KLF4 KCNH4 TNS1	5.79e-06	196	112	8	4225_UP
Drug	Paclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A	SOX9 ELOA2 ATN1 OGFR RPS6KA2 KLF4 ZNF783 ZFP36L2	5.79e-06	196	112	8	5320_UP
Drug	Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A	OGFR RPS6KA2 IQSEC2 ZNF446 ZNF783 ZFP36L2 ZNF589 AUTS2	5.79e-06	196	112	8	4958_UP
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A	CACNA1A ATN1 OGFR ZNF783 SOX21 SMG7 FUT4 TNS1	6.01e-06	197	112	8	4631_DN
Drug	Atracurium besylate [64228-81-5]; Up 200; 3.2uM; MCF7; HT_HG-U133A	OGFR BCL2 MAP3K1 CITED2 NCOR2 AUTS2 FUT4 RCN3	6.01e-06	197	112	8	1702_UP
Drug	Nadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A	DVL3 BCL2 KLF4 MAP3K1 ZNF589 DYRK1B TNS1 MN1	6.01e-06	197	112	8	6091_UP
Drug	Racecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A	SOX9 OGFR FBRS IRF7 KLF4 ZNF783 GLI3 ZNF589	6.23e-06	198	112	8	2774_DN
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A	CACNA1A ELOA2 ATN1 RPS6KA2 KLF4 ZNF446 AXIN1 NCOR2	6.71e-06	200	112	8	6612_DN
Drug	forskolin; Up 200; 50uM; MCF7; HT_HG-U133A_EA	RPS6KA2 DIDO1 SIK1 BCL2 ZNF446 MAP3K1 CITED2	1.28e-05	157	112	7	913_UP
Drug	retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A	SOX9 DVL3 SIK1 NCOR2 ZFP36L2 CLTB FUT4	2.88e-05	178	112	7	1636_UP
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	DIDO1 KLF4 CITED2 PPP1R8 ZFP36L2 USPL1 CDCA4	3.56e-05	184	112	7	5671_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; MCF7; HT_HG-U133A	SOX9 INHBE OGFR DVL3 KLF4 MAP3K1 AUTS2	4.22e-05	189	112	7	3408_UP
Drug	Perphenazine [58-39-9]; Up 200; 10uM; PC3; HT_HG-U133A	ZNF219 ARID3A CUBN KLF4 SOX21 ZNF589 CLTB	4.37e-05	190	112	7	4637_UP
Drug	15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A	TEDC2 GATA2 BCL2 CITED2 ZFP36L2 ZNF589 FUT4	4.37e-05	190	112	7	1172_DN
Drug	Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ATN1 OGFR RPS6KA2 IQSEC2 ZFP36L2 ZNF589 MMP13	4.52e-05	191	112	7	3574_UP
Drug	Megestrol acetate [595-33-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A	OGFR IQSEC2 BCL2 ZFP36L2 ZNF589 FUT4 RCN3	4.67e-05	192	112	7	5013_UP
Drug	Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A	INHBE RPS6KA2 GAS7 POU4F1 BCL2 ZFP36L2 ZNF589	4.67e-05	192	112	7	2807_UP
Drug	0393-0188; Up 200; 10uM; PC3; HT_HG-U133A	SOX10 OGFR RPS6KA2 KLF4 ZFP36L2 ULK1 TNS1	4.67e-05	192	112	7	7536_UP
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; MCF7; HT_HG-U133A	OGFR ZNF783 AXIN1 GLI3 ZNF589 HMGXB3 FUT4	4.98e-05	194	112	7	2824_DN
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	INHBE OGFR DVL3 ZNF783 ZNF589 AUTS2 TNS1	4.98e-05	194	112	7	4961_UP
Drug	PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A	ZNF219 ARID3A ATN1 GPR135 BCL2 ZIC3 SOX21	4.98e-05	194	112	7	6368_UP
Drug	Doxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A	ATN1 OGFR FBRS AXIN1 CITED2 ZFP36L2 RCN3	5.15e-05	195	112	7	4235_DN
Drug	Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	ATN1 OGFR DVL3 GAS7 CLTB AUTS2 RCN3	5.15e-05	195	112	7	4180_DN
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	OGFR FBRS GAS7 ZIC3 CITED2 TNS1 PROX1	5.15e-05	195	112	7	4300_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	ATN1 OGFR GATA2 DVL3 GAS7 ZNF446 ZIC3	5.32e-05	196	112	7	5604_DN
Drug	Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; MCF7; HT_HG-U133A	CACNA1A RPS6KA2 IQSEC2 SIK1 POU4F1 ZNF446 ZFP36L2	5.32e-05	196	112	7	2232_DN
Drug	Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A	CACNA1A FBRS ZNF783 ZFP36L2 MN1 RCN3 PROX1	5.32e-05	196	112	7	4587_DN
Drug	Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A	NTNG1 GPR135 MAP3K1 SOX21 MED22 TNS1 PROX1	5.32e-05	196	112	7	6715_UP
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	ARID3A GPR135 ZNF783 ZNF589 FUT4 MMP13 RCN3	5.49e-05	197	112	7	7495_UP
Drug	PF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A	ATN1 RPS6KA2 IQSEC2 DVL3 KLF4 ZNF446 TNS1	5.49e-05	197	112	7	5939_UP
Drug	genistein; Down 200; 10uM; HL60; HT_HG-U133A	INHBE GATA2 BCL2 AXIN1 MED22 FUT4 TNS1	5.49e-05	197	112	7	2695_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A	ZNF219 DVL3 NTNG1 ZNF446 MAP3K1 MMP13 TNS1	5.49e-05	197	112	7	3824_DN
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A	OGFR IQSEC2 GAS7 ZNF446 ZIC3 ZFP36L2 RCN3	5.49e-05	197	112	7	6105_DN
Drug	Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; PC3; HT_HG-U133A	ZNF219 ELOA2 ATN1 RPS6KA2 POU4F1 ZNF783 ZFP36L2	5.49e-05	197	112	7	6705_UP
Drug	C75; Down 200; 10uM; PC3; HT_HG-U133A	ZNF219 ARID3A RPS6KA2 GPR135 MED22 ZNF589 MMP13	5.49e-05	197	112	7	6428_DN
Drug	Alprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A	CACNA1A ATN1 GAS7 DIDO1 BCL2 ZIC3 NCOR2	5.67e-05	198	112	7	4099_DN
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; PC3; HT_HG-U133A	OGFR KLF4 SOX21 ZFP36L2 ZNF589 CLTB RCN3	5.67e-05	198	112	7	6698_UP
Drug	Doxycycline hydrochloride [10592-13-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	SOX9 DVL3 DIDO1 MAP3K1 ZFP36L2 ZNF589 FUT4	5.67e-05	198	112	7	3479_UP
Drug	iloprost; Down 200; 1uM; SKMEL5; HG-U133A	OGFR DIDO1 IRF7 AXIN1 ZFP36L2 CLTB TNS1	5.67e-05	198	112	7	496_DN
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; HL60; HT_HG-U133A	CACNA1A FBRS GAS7 IRF7 MAP3K1 TNS1 RCN3	5.67e-05	198	112	7	2555_DN
Drug	Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; HL60; HT_HG-U133A	ZNF219 OGFR PAK5 IQSEC2 MAP3K1 AXIN1 GLI3	5.67e-05	198	112	7	2173_UP
Drug	Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A	INHBE ZNF219 ELOA2 OGFR RPS6KA2 GAS7 DYRK1B	5.67e-05	198	112	7	5110_UP
Drug	Famotidine [76824-35-6]; Down 200; 11.8uM; PC3; HT_HG-U133A	RPS6KA2 IQSEC2 GATA2 KLF4 AXIN1 SMG7 ZFP36L2	5.85e-05	199	112	7	6665_DN
Drug	SC-58125; Up 200; 10uM; MCF7; HG-U133A	ATN1 GPR135 CUBN AXIN1 NCOR2 SCN5A TNS1	5.85e-05	199	112	7	254_UP
Drug	Furazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ELOA2 OGFR NCOR2 ZNF589 FUT4 MMP13 MN1	5.85e-05	199	112	7	4178_UP
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	ATN1 RPS6KA2 FBRS DVL3 SIK1 BCL2 RCN3	6.04e-05	200	112	7	6963_UP
Drug	Aminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	SOX10 INHBE OGFR BCL2 SMG7 SCN5A MMP13	6.04e-05	200	112	7	3623_UP
Drug	Taylor's blue	SOX9 SOX10 MMP13	8.96e-05	18	112	3	CID000123898
Drug	thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	SOX9 INHBE RPS6KA2 SIK1 ZNF446 AXIN1	1.24e-04	156	112	6	1010_UP
Drug	Niclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	INHBE KLF4 ZNF446 MAP3K1 ZFP36L2 ULK1	1.57e-04	163	112	6	1498_UP
Drug	1,3,2-dioxaborolan-2-ol	IL10RA INHBE KLF4 AXIN1 DACH2	1.64e-04	104	112	5	CID005289333
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	TRIP6 OGFR DIDO1 BCL2 ZNF783 SAFB	1.68e-04	165	112	6	2835_DN
Drug	tamibarotene	CDK8 USP9X GATA2 IRF7 BCL2 SEC31A AXIN1 NCOR2 CLTB ANKRD17 FUT4	1.74e-04	596	112	11	ctd:C061133
Drug	Ciclopirox ethanolamine [41621-49-2]; Up 200; 15uM; PC3; HT_HG-U133A	ARID3A NTNG1 GPR135 KLF4 CITED2 NCOR2	1.79e-04	167	112	6	6677_UP
Drug	Cycloheximide [66-81-9]; Down 200; 14.2uM; HL60; HT_HG-U133A	INHBE RPS6KA2 GATA2 BCL2 ZNF589 FUT4	2.04e-04	171	112	6	2723_DN
Drug	SAHA; Down 200; 10uM; HL60; HT_HG-U133A	TRIP6 BCL2 ZFP36L2 DENND4B FUT4 TNS1	2.31e-04	175	112	6	1161_DN
Drug	SC-203048	BCL2 NCOR2	2.38e-04	5	112	2	ctd:C572332
Drug	idoxifene	BCL2 SOD1	2.38e-04	5	112	2	ctd:C071362
Drug	Carboplatin	SIK1 BCL2 MAP3K1 CITED2 SOD1	2.42e-04	113	112	5	ctd:D016190
Drug	Parthenolide [20554-84-1]; Down 200; 16.2uM; HL60; HG-U133A	IL10RA TRIP6 GAS7 BCL2 CITED2 ZFP36L2	2.53e-04	178	112	6	1736_DN
Drug	Alexidine dihydrochloride [22573-93-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A	CACNA1A SOX9 INHBE NCOR2 MMP13 PROX1	2.61e-04	179	112	6	4721_UP
Drug	Propofol [2078-54-8]; Up 200; 22.4uM; MCF7; HT_HG-U133A	INHBE OGFR IRF7 KLF4 SMG7 ZNF589	2.69e-04	180	112	6	5306_UP
Drug	H-7 dihydrochloride; Down 200; 100uM; PC3; HT_HG-U133A	SOX9 DIDO1 SIK1 SF1 ZFP36L2 CDCA4	2.85e-04	182	112	6	5941_DN
Drug	Dimaprit dihydrochloride [23256-33-9]; Down 200; 17uM; HL60; HT_HG-U133A	INHBE OGFR GATA2 BCL2 ZNF783 FUT4	2.85e-04	182	112	6	3141_DN
Drug	Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A	SOX9 RPS6KA2 SF1 SMG7 ZFP36L2 ZNF589	2.94e-04	183	112	6	1709_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT_HG-U133A	SOX9 DIDO1 KLF4 ZFP36L2 GLI3 CDCA4	3.02e-04	184	112	6	4610_DN
Drug	2-propylpentanoic acid; Down 200; 1000uM; HL60; HT_HG-U133A	INHBE ELOA2 FBRS SIK1 IRF7 NCOR2	3.30e-04	187	112	6	2669_DN
Drug	Rescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A	SOX10 INHBE ELOA2 ARID3A ATN1 PAK5	3.39e-04	188	112	6	4386_UP
Drug	H-7 dihydrochloride; Down 200; 100uM; MCF7; HT_HG-U133A	GATA2 GATA6 SIK1 KLF4 CITED2 ZFP36L2	3.49e-04	189	112	6	5936_DN
Drug	Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A	ATN1 IQSEC2 DVL3 NCOR2 SOX21 PROX1	3.49e-04	189	112	6	4304_UP
Drug	Strophantine octahydrate [11018-89-6]; Down 200; 5.4uM; PC3; HT_HG-U133A	SOX9 TEDC2 GAS7 FUT4 TNS1 MN1	3.59e-04	190	112	6	6680_DN
Drug	LY294002; Up 200; 10uM; MCF7; HG-U133A	CDK8 CD2AP ZNF446 AXIN1 CITED2 DYRK1B	3.59e-04	190	112	6	328_UP
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A	SOX9 ELOA2 SF1 MAP3K1 SMG7 ZFP36L2	3.59e-04	190	112	6	5614_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	TEDC2 FBRS IRF7 SMG7 ZFP36L2 CDCA4	3.69e-04	191	112	6	998_DN
Drug	17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A	ATN1 OGFR TEDC2 FBRS GPR135 KLF4	3.69e-04	191	112	6	4437_DN
Drug	Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A	SOX9 OGFR TEDC2 SMG7 ZFP36L2 ZNF589	3.69e-04	191	112	6	6644_DN
Drug	Desipramine hydrochloride [58-28-6]; Up 200; 13.2uM; PC3; HT_HG-U133A	RPS6KA2 KLF4 ZNF783 ZNF589 MMP13 PROX1	3.69e-04	191	112	6	6693_UP
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A	ATN1 IQSEC2 GAS7 DIDO1 MSRB2 HMGXB3	3.69e-04	191	112	6	3890_DN
Drug	Niclosamide [50-65-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	SOX9 SMG7 ZFP36L2 ZNF589 TNS1 MN1	3.79e-04	192	112	6	4018_DN
Drug	troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	SOX9 GATA6 GAS7 SIK1 ZFP36L2 GLI3	3.90e-04	193	112	6	6949_UP
Drug	Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A	PAK5 GAS7 NCOR2 ZNF589 CLTB TNS1	3.90e-04	193	112	6	2283_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A	ATN1 RPS6KA2 GATA2 NCOR2 SMG7 ZNF589	3.90e-04	193	112	6	5922_UP
Drug	Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	OGFR DVL3 ZNF783 NCOR2 ZNF589 PROX1	3.90e-04	193	112	6	4536_UP
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	OGFR ZNF446 SMG7 ZFP36L2 ZNF589 ULK1	3.90e-04	193	112	6	5215_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	SOX9 ELOA2 GATA2 GAS7 FUT4 TNS1	3.90e-04	193	112	6	5602_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	IQSEC2 FBRS SIK1 ZNF446 TBC1D8 ZFP36L2	4.01e-04	194	112	6	7001_UP
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A	ARID3A GPR135 GAS7 ZNF446 ZNF783 ZFP36L2	4.01e-04	194	112	6	6710_UP
Drug	Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A	SOX9 POU4F1 ZNF446 ZNF783 MAP3K1 SMG7	4.01e-04	194	112	6	5450_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	ATN1 OGFR ZNF783 AXIN1 ZFP36L2 RCN3	4.01e-04	194	112	6	4331_DN
Disease	ventricular septal defect (is_implicated_in)	GATA6 NKX2-6 CITED2	1.59e-05	14	106	3	DOID:1657 (is_implicated_in)
Disease	Tetralogy of Fallot	GATA6 NKX2-6 CITED2	2.44e-05	16	106	3	C0039685
Disease	Adenocarcinoma of large intestine	CDK8 RPS6KA2 PAK5 AXIN1 UBR5	2.56e-05	96	106	5	C1319315
Disease	Feeding difficulties	CDK8 ATN1 MN1	3.54e-05	18	106	3	C0232466
Disease	Metastatic melanoma	RPS6KA2 PAK5 SIK1 DYRK1B	4.33e-05	54	106	4	C0278883
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	GATA6 NKX2-6 SCN5A	6.60e-05	22	106	3	C1843687
Disease	CONOTRUNCAL HEART MALFORMATIONS	GATA6 NKX2-6	7.63e-05	4	106	2	217095
Disease	Conotruncal heart malformations	GATA6 NKX2-6	7.63e-05	4	106	2	cv:C1857586
Disease	Acute Myeloid Leukemia, M1	GATA2 POU4F1 BCL2 KMT2C MN1	9.06e-05	125	106	5	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	GATA2 POU4F1 BCL2 KMT2C MN1	9.06e-05	125	106	5	C1879321
Disease	anodontia (is_implicated_in)	GLI3 MMP13	1.27e-04	5	106	2	DOID:13714 (is_implicated_in)
Disease	Klatskin's tumor (is_implicated_in)	GATA6 KMT2C	1.27e-04	5	106	2	DOID:4927 (is_implicated_in)
Disease	laryngeal carcinoma (is_marker_for)	KMT2C UBR5	1.90e-04	6	106	2	DOID:2600 (is_marker_for)
Disease	CONOTRUNCAL HEART MALFORMATIONS (disorder)	GATA6 NKX2-6	1.90e-04	6	106	2	C1857586
Disease	Intellectual Disability	CDK8 SOX9 ATN1 PITRM1 PTPN23 KMT2C MN1 MED13	2.15e-04	447	106	8	C3714756
Disease	Swyer Syndrome	SOX9 MAP3K1	2.65e-04	7	106	2	C2936694
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A PITRM1	2.65e-04	7	106	2	DOID:0050951 (implicated_via_orthology)
Disease	Gonadal Dysgenesis, 46,XY	SOX9 MAP3K1	3.53e-04	8	106	2	C0018054
Disease	AUTISM, SUSCEPTIBILITY TO, 15	CDK8 AUTS2	3.53e-04	8	106	2	C2677504
Disease	reticulocyte count	ARID3A USP9X CD2AP BCL2 ADCY8 MAP3K1 TBC1D8 ZFP36L2 CPEB4 MMP13 TNS1 FERMT3	3.78e-04	1045	106	12	EFO_0007986
Disease	Leukemia, Myelocytic, Acute	GATA2 POU4F1 BCL2 KMT2C MN1	4.11e-04	173	106	5	C0023467
Disease	Anorectal Malformations	CDK8 ZIC3 GLI3	4.35e-04	41	106	3	C3495676
Disease	Ostium secundum atrial septal defect	GATA6 CITED2	4.53e-04	9	106	2	C0344724
Disease	46,XY partial gonadal dysgenesis	SOX9 MAP3K1	6.88e-04	11	106	2	C4510744
Disease	chronic kidney disease, Proteinuria	CACNA1A GAS7	6.88e-04	11	106	2	EFO_0003884, HP_0000093
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	FBRSL1 TBC1D8 CPEB4	7.36e-04	49	106	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	acute myeloid leukemia (is_marker_for)	GATA2 BCL2 FERMT3	7.36e-04	49	106	3	DOID:9119 (is_marker_for)
Disease	myeloid leukemia (is_implicated_in)	GATA2 MN1	9.72e-04	13	106	2	DOID:8692 (is_implicated_in)
Disease	Colorectal Carcinoma	ELOA2 NTNG1 BCL2 CUBN ADCY8 KCNH4 KMT2C ZFP36L2 GLI3	9.80e-04	702	106	9	C0009402
Disease	familial atrial fibrillation (is_implicated_in)	NKX2-6 SCN5A	1.13e-03	14	106	2	DOID:0050650 (is_implicated_in)
Disease	Diabetes Mellitus, Non-Insulin-Dependent	BCL2 NFATC2 AUTS2 SOD1 PROX1	1.24e-03	221	106	5	C0011860
Disease	Muscular Atrophy	CITED2 SOD1	1.30e-03	15	106	2	C0026846
Disease	Generalized hypotonia	CDK8 ATN1	1.30e-03	15	106	2	C1858120
Disease	Neurogenic Muscular Atrophy	CITED2 SOD1	1.30e-03	15	106	2	C0270948
Disease	PROSTATE CANCER, HEREDITARY, 1	FBRSL1 BCL2 DENND4B	1.33e-03	60	106	3	C4722327
Disease	teratocarcinoma-derived growth factor 1 measurement	GAS7 TNS1	1.48e-03	16	106	2	EFO_0008297
Disease	syndromic intellectual disability (implicated_via_orthology)	DYRK1B AUTS2	1.48e-03	16	106	2	DOID:0050888 (implicated_via_orthology)
Disease	Cardiovascular Abnormalities	ATN1 GATA2	1.48e-03	16	106	2	C0243050
Disease	Prostate cancer, familial	FBRSL1 BCL2 DENND4B	1.99e-03	69	106	3	C2931456
Disease	end stage renal disease (implicated_via_orthology)	CD2AP BCL2	2.33e-03	20	106	2	DOID:783 (implicated_via_orthology)
Disease	lung cancer (is_implicated_in)	SOX9 DVL3 AXIN1	2.43e-03	74	106	3	DOID:1324 (is_implicated_in)
Disease	Craniofacial Abnormalities	SOX9 GATA2 ZIC3 MMP13	2.46e-03	156	106	4	C0376634
Disease	glucose measurement	FBRSL1 AXIN1 ZFP36L2 GLI3 AUTS2 PROX1	2.54e-03	380	106	6	EFO_0004468
Disease	Retinal Degeneration	BCL2 SOD1	2.57e-03	21	106	2	C0035304
Disease	Disproportionate short stature	SOX9 GLI3 MMP13	2.72e-03	77	106	3	C0878659
Disease	liver cirrhosis (is_marker_for)	AXIN1 GLI3 CPEB4	3.25e-03	82	106	3	DOID:5082 (is_marker_for)
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	GATA6 SOD1	3.35e-03	24	106	2	DOID:3827 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VPGLAAHPGSHSDQP	nan	86	A8MUN3
PAGGGPNHHAPQLSG	ADCY8	71	P40145
PHGSLGHAGLPQSPA	CACNA1A	1081	O00555
AAHPASNPFGPSAHP	FBRSL1	656	Q9HCM7
GGTGSELHHFPPTSP	CEP128	116	Q6ZU80
HGFPPTLGGHSFEPS	ALX3	301	O95076
QQHHGNSGPPPPGAF	ATN1	501	P54259
LPGRFNGGHSPTHSP	CD2AP	501	Q9Y5K6
AGGPIFNGPHAADPS	ANKRD17	2551	O75179
TGGIGDSRPPSFHPH	DVL3	106	Q92997
DSRPPSFHPHAGGGS	DVL3	111	Q92997
SPFAAPGPQHGIAHA	DACH2	271	Q96NX9
GHGPFSGFPGPQEHT	DYRK1B	6	Q9Y463
HPGHQPGSAGQSPDL	NKX2-1	316	P43699
HGAQGKPSPDAGPHG	RCN3	16	Q96D15
GPAPHTPLASAGFGH	NKX2-6	266	A6NCS4
HFRGHPALSGSPDPQ	RIMBP3B	206	A6NNM3
HFRGHPALSGSPDPQ	RIMBP3C	206	A6NJZ7
PIPAQHHFSSGIPAG	PTPN23	931	Q9H3S7
HSEGNGASGLPHYPP	MEOX1	26	P50221
GTLPPPSHGAFSGHH	CDC42BPG	376	Q6DT37
PTPDQGASSHGPGHA	PAK5	106	Q9P286
HGAPFAGHLPRGSPV	NCOR2	1546	Q9Y618
SHVAPQDHGSPAGYP	NFATC2	281	Q13469
PSGLPHPGLVAAAAH	POU4F1	211	Q01851
PAAPGKQPGRGHTHA	ELOA2	186	Q8IYF1
GPPLSNGHRPAAHDF	KLF4	291	O43474
GSAFGHSPPLIHPAP	GLI3	371	P10071
QHAPGPGGAAHPAQA	GPR88	251	Q9GZN0
HLPHNSLPPGSGLGT	KMT2C	1571	Q8NEZ4
GSFHGVFPGPPASSH	MAFIP	11	Q8WZ33
HLGPQHLPPGSSTSG	DTX2	286	Q86UW9
HGTPGPEGNHISDLP	IBTK	1246	Q9P2D0
GQGPRPLHSGTAPFH	FUT4	71	P22083
LQVAAPAHSHAGGPG	MED22	181	Q15528
PGGSYSHPHHPQSPL	IQSEC2	1411	Q5JU85
GLQPNPGDPSAGHHS	HMGXB3	1176	Q12766
PPHLAGSPGIAASFH	INHBE	281	P58166
AHAFPPGPNYGGDAH	MMP13	186	P45452
TGTPFGPPPHHSNFL	AUTS2	721	Q8WXX7
LAGQGHSASPHGPPR	KCNH4	786	Q9UQ05
TQGGSALGHHSPPEP	IL10RA	416	Q13651
QGGPPGPFLAHTHAG	IRF7	151	Q92985
GQPGHPNTGGAAAHP	PRR25	16	Q96S07
GPAPAGSPSQHQFHP	TENT4A	151	Q5XG87
PSAFKGPSHSGNPSH	PROSER1	616	Q86XN7
PSVHKPSAGQGHPSA	BOD1L1	2411	Q8NFC6
GTIQSPGHPNVYPHG	CUBN	941	O60494
PTAAHSGSHLFGFPP	GATA2	161	P23769
SSYASHPFGAPHGPS	GATA6	81	Q92908
HPFGAPHGPSAPGVA	GATA6	86	Q92908
DPAHVSHAPSGAPGQ	EEF1DP3	111	Q658K8
AAPGAHGPFLSPSTH	FBRS	156	Q9HAH7
LGSQHSGAPSAAGPP	GPR135	16	Q8IZ08
GSLGSVAPPPGGHSH	GGT6	86	Q6P531
SPGPGHRSPDSGHVA	AXIN1	486	O15169
GHFVGPRGPHPSQFE	DIDO1	1921	Q9BTC0
PYSHSANLAPPGPGH	DENND4B	126	O75064
QTPGPHPGHQLLLFG	KLHDC9	196	Q8NEP7
PHHVSPGFGGSFSPQ	CPEB4	211	Q17RY0
GHPGNQDSSHTQGPP	CDK8	386	P49336
LAGSPAPSGHPKAGH	OGFR	481	Q9NZT2
NTHFKAPAFHTGGPP	MN1	31	Q10571
PPPHGAASRGGAHLT	MAP3K1	111	Q13233
DSGQGAPPHGSPALL	NTNG1	511	Q9Y2I2
THPPGHPGQQGYVVS	FREM3	351	P0C091
SPGNHGNHYSDGPNP	USP9X	986	Q93008
GHTHSHPSPGNPGYM	SOX21	221	Q9Y651
YPGQHGPAHPAFSIG	TBR1	126	Q16650
GLPPTHSEAGSQPHG	PPP1R8	266	Q12972
VSPGPASGVPHHGES	SSPOP	2326	A2VEC9
APPHSPGQAGGHASD	TEDC2	121	Q7L2K0
HFRGHPALSGSPDPQ	RIMBP3	206	Q9UFD9
GFAAPHGLATPHPNS	PIANP	131	Q8IYJ0
PPTVNGYHASGTPAH	GAS7	126	O60861
GYHASGTPAHPPETA	GAS7	131	O60861
SASGPAAGGHHQPLH	PROX1	451	Q92786
PALGKSPPHHSGFQQ	SMG7	776	Q92540
PVPSSSGGDAHVPHG	PITRM1	821	Q5JRX3
PSPGTSAPGHALHGK	SCN5A	576	Q14524
SPFHAPAQSPGLHGG	SIK1B	626	A0A0B4J2F2
SPFHAPAQSPGLHGG	SIK1	626	P57059
PRAHPAGSFHAGPGD	ST6GAL2	81	Q96JF0
HFHSGGMPAPASPNR	PRR32	281	B1ATL7
VHSPGEHSGQSQGPP	SOX9	221	P48436
GSPVHSPGSHYPHGG	MED13	2021	Q9UHV7
HSPGGAQAPTNLSGP	SOX1	11	O00570
AGPHFNPLSRKHGGP	SOD1	61	P00441
SFAPGGASRGHPIPH	SAFB	876	Q15424
GAAPAPGIFSSQPGH	BCL2	41	P10415
GPAHPGGAAHVAPQL	ARID3A	201	Q99856
AHPAPGLGDGHTQGP	CDCA4	111	Q9BXL8
GTVNGGHPPSALAPA	CITED2	76	Q99967
HAAPAQPGPTSGAGS	CLTB	51	P09497
LFPGLHEQGAGHPSP	ZIC3	161	O60481
GPPSSNGTAAHPHAH	USPL1	831	Q5W0Q7
RGASQASGPLPGPHF	TRIP6	186	Q15654
GHAFPSPLDPGHSSV	ZP1	176	P60852
AHLGHVFPDGPGPNG	MSRB2	151	Q9Y3D2
LGGDAGSPAPPFHSS	PAPLN	891	O95428
SPGPPVGSHHAFFSD	TBC1D8	736	O95759
GSPSAAGPGFPAALH	SOGA1	1081	O94964
SNAPGPPLHIGASHL	SAP130	216	Q9H0E3
PAEASGSGPGSPHLH	TNKS1BP1	291	Q9C0C2
TPGSPSLGRHPGAHQ	TNS1	1266	Q9HBL0
LPPNGHPGHVSSYSA	SOX10	301	P56693
LPHPSVSHGNGDQGP	USF3	1951	Q68DE3
GPGNHPHGPDASAEG	FERMT3	486	Q86UX7
GAPHGAPHSDSPLGF	TNXA	6	Q16473
SPPLAAQSPEGNHGH	ZNF446	181	Q9NWS9
PIPGFHAGNQLHPGN	ZNF589	106	Q86UQ0
ASFQHGGPGAPPSSS	SEC31A	951	O94979
SFPQPHLPGGQPFHG	SEC31A	1051	O94979
SGFPSGHHQPPGGLE	ZFP36L2	261	P47974
GSRANPGDPQPHFSH	VWA7	641	Q9Y334
TNTRPGAHPPEHGGV	nan	91	Q6ZTI0
GAHPPEHGGVAALPA	nan	96	Q6ZTI0
LASGPQAAGASPHPH	XIRP1	1236	Q702N8
SFPHPLPSLTGGHGG	SF1	396	Q15637
ASPSPPAHAEHGGVL	ULK1	476	O75385
SLHPRPGEGPGHSAS	ZNF219	451	Q9P2Y4
GSALASAGDPGHPNH	UBR5	1856	O95071
VGPHFPAAPARHGSL	ZNF783	521	Q6ZMS7
PGVPPSANAHHLFRG	RPS6KA2	361	Q15349