Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXO3 FOXJ3 CREB5 POU4F2 USF3 PAX6	1.79e-05	560	21	6	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	FOXO3 FOXJ3 CREB5 POU4F2 USF3 PAX6	1.91e-05	566	21	6	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF711 FOXO3 FOXJ3 CREB5 POU4F2 USF3 PAX6 YLPM1	5.42e-05	1412	21	8	GO:0000981
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	FOXO3 POU4F2 PAX6 YLPM1	3.12e-04	320	21	4	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	FOXO3 POU4F2 PAX6 YLPM1	3.35e-04	326	21	4	GO:0001217
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF711 FOXO3 FOXJ3 CREB5 POU4F2 USF3 PAX6	5.11e-04	1459	21	7	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF711 FOXO3 FOXJ3 CREB5 POU4F2 PAX6	1.39e-03	1244	21	6	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF711 FOXO3 FOXJ3 CREB5 POU4F2 PAX6	1.56e-03	1271	21	6	GO:0000987
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZNF711 KAT6B FOXO3 FOXJ3 CREB5 POU4F2 USF3 MED4 PAX6	3.91e-06	1390	21	9	GO:0045944
GeneOntologyBiologicalProcess	ovulation from ovarian follicle	FOXO3 ADAMTS1	1.03e-04	15	21	2	GO:0001542
GeneOntologyBiologicalProcess	negative regulation of neuron differentiation	FOXO3 POU4F2 PAX6	1.15e-04	94	21	3	GO:0045665
GeneOntologyBiologicalProcess	positive regulation of transcription regulatory region DNA binding	POU4F2 PAX6	1.86e-04	20	21	2	GO:2000679
GeneOntologyBiologicalProcess	ovulation	FOXO3 ADAMTS1	2.69e-04	24	21	2	GO:0030728
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	KAT6B FOXO3 TLE3 POU4F2 PAX6 YLPM1 BCL7A	3.25e-04	1399	21	7	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	KAT6B FOXO3 TLE3 POU4F2 PAX6 YLPM1 BCL7A	3.45e-04	1413	21	7	GO:1902679
GeneOntologyCellularComponent	chromatin	ZNF711 KAT6B FOXO3 FOXJ3 CREB5 POU4F2 PAX6 BCL7A	5.47e-05	1480	21	8	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	FOXO3 TLE3 POU4F2 MED4 PAX6	2.58e-04	596	21	5	GO:0005667
MousePheno	unresponsive to tactile stimuli	FOXJ3 USF3 BCL7A	1.25e-04	73	19	3	MP:0001491
MousePheno	abnormal reflex	SCN10A FOXO3 FOXJ3 POU4F2 USF3 YLPM1 MIPEP BCL7A	1.57e-04	1294	19	8	MP:0001961
MousePheno	abnormal endocrine pancreas development	TLE3 PAX6	2.95e-04	19	19	2	MP:0011932
MousePheno	abnormal lacrimal apparatus morphology	KAT6B PAX6	3.98e-04	22	19	2	MP:0008968
MousePheno	abnormal sensory capabilities/reflexes/nociception	SCN10A FOXO3 FOXJ3 POU4F2 USF3 YLPM1 MIPEP BCL7A	4.12e-04	1486	19	8	MP:0002067
MousePheno	abnormal ear position	KAT6B PAX6	6.48e-04	28	19	2	MP:0000023
MousePheno	absent allantois	SLC31A1 PRKCI	7.44e-04	30	19	2	MP:0003087
MousePheno	lymphoid hyperplasia	FOXO3 IL12RB2	7.44e-04	30	19	2	MP:0000688
MousePheno	large lymphoid organs	FOXO3 IL12RB2	9.01e-04	33	19	2	MP:0002220
MousePheno	abnormal spinal reflex	FOXJ3 USF3 BCL7A	9.95e-04	148	19	3	MP:0012079
MousePheno	abnormal response to tactile stimuli	FOXJ3 USF3 BCL7A	9.95e-04	148	19	3	MP:0005316
MousePheno	abnormal cortical plate morphology	KAT6B PAX6	1.01e-03	35	19	2	MP:0008439
MousePheno	abnormal tectum morphology	KAT6B POU4F2	1.01e-03	35	19	2	MP:0006104
MousePheno	abnormal midbrain roof plate morphology	KAT6B POU4F2	1.01e-03	35	19	2	MP:0006103
MousePheno	abnormal pancreas development	TLE3 PAX6	1.01e-03	35	19	2	MP:0003934
MousePheno	abnormal corpora quadrigemina morphology	KAT6B POU4F2	1.01e-03	35	19	2	MP:0000899
MousePheno	abnormal midbrain morphology	KAT6B POU4F2 PAX6	1.05e-03	151	19	3	MP:0000897
MousePheno	salivary gland inflammation	FOXO3 IL12RB2	1.20e-03	38	19	2	MP:0001870
MousePheno	abnormal touch/ nociception	SCN10A FOXJ3 USF3 BCL7A	1.45e-03	376	19	4	MP:0001968
Domain	-	KAT6B FOXO3 FOXJ3 PAX6	9.25e-05	218	21	4	1.10.10.10
Domain	WHTH_DNA-bd_dom	KAT6B FOXO3 FOXJ3 PAX6	1.38e-04	242	21	4	IPR011991
Domain	TF_fork_head_CS_2	FOXO3 FOXJ3	1.21e-03	46	21	2	IPR030456
Domain	TF_fork_head_CS_1	FOXO3 FOXJ3	1.26e-03	47	21	2	IPR018122
Domain	FORK_HEAD_3	FOXO3 FOXJ3	1.37e-03	49	21	2	PS50039
Domain	FH	FOXO3 FOXJ3	1.37e-03	49	21	2	SM00339
Domain	FORK_HEAD_1	FOXO3 FOXJ3	1.37e-03	49	21	2	PS00657
Domain	FORK_HEAD_2	FOXO3 FOXJ3	1.37e-03	49	21	2	PS00658
Domain	Forkhead	FOXO3 FOXJ3	1.37e-03	49	21	2	PF00250
Domain	Fork_head_dom	FOXO3 FOXJ3	1.37e-03	49	21	2	IPR001766
Domain	Prefoldin	TLE3 CFAP57	2.94e-03	72	21	2	IPR009053
Domain	MetalloPept_cat_dom	ADAMTS1 MIPEP	3.70e-03	81	21	2	IPR024079
Domain	-	ADAMTS1 MIPEP	3.70e-03	81	21	2	3.40.390.10
Domain	ZINC_PROTEASE	ADAMTS1 MIPEP	5.36e-03	98	21	2	PS00142
Domain	Homeobox_CS	POU4F2 PAX6	1.83e-02	186	21	2	IPR017970
Pubmed	Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development.	PRKCI POU4F2 PAX6	1.06e-07	16	21	3	16959241
Pubmed	Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina.	PRKCI POU4F2 PAX6	3.33e-07	23	21	3	16267237
Pubmed	Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.	PRKCI POU4F2 PAX6	5.50e-07	27	21	3	26628093
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF711 FOXO3 FOXJ3 CREB5 POU4F2 USF3 PAX6	6.82e-07	908	21	7	19274049
Pubmed	Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors.	FOXO3 FOXJ3	1.04e-06	3	21	2	26578569
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KAT6B FOXO3 SLC31A1 FOXJ3 DTNB PRKCI TLE3 USF3	1.37e-06	1489	21	8	28611215
Pubmed	The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons.	POU4F2 PAX6	2.08e-06	4	21	2	15233918
Pubmed	Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6.	POU4F2 PAX6	5.20e-06	6	21	2	12756174
Pubmed	AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle.	POU4F2 PAX6	5.20e-06	6	21	2	9918694
Pubmed	Negative regulation of Vsx1 by its paralog Chx10/Vsx2 is conserved in the vertebrate retina.	POU4F2 PAX6	7.28e-06	7	21	2	17919464
Pubmed	Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells.	POU4F2 PAX6	7.28e-06	7	21	2	27402841
Pubmed	A Novel Reporter Mouse Uncovers Endogenous Brn3b Expression.	POU4F2 PAX6	9.70e-06	8	21	2	31197108
Pubmed	Effects of caloric restriction and growth hormone resistance on insulin-related intermediates in the skeletal muscle.	FOXO3 PRKCI	1.25e-05	9	21	2	17301033
Pubmed	Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina.	POU4F2 PAX6	1.25e-05	9	21	2	12724837
Pubmed	Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.	PRKCI PAX6	1.56e-05	10	21	2	32150534
Pubmed	RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.	POU4F2 PAX6	1.56e-05	10	21	2	23805044
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TLE3 MED4 YLPM1 BCL7A	1.86e-05	268	21	4	33640491
Pubmed	Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Müller glial cell development.	POU4F2 PAX6	1.90e-05	11	21	2	18626943
Pubmed	Delayed expression of the Crx gene and photoreceptor development in the Chx10-deficient retina.	POU4F2 PAX6	1.90e-05	11	21	2	14744875
Pubmed	Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina.	POU4F2 PAX6	1.90e-05	11	21	2	28356311
Pubmed	Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells.	POU4F2 PAX6	1.90e-05	11	21	2	17661397
Pubmed	Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.	POU4F2 PAX6	1.90e-05	11	21	2	16343477
Pubmed	Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye.	POU4F2 PAX6	1.90e-05	11	21	2	11069887
Pubmed	Molecular mechanisms controlling midline crossing by precerebellar neurons.	POU4F2 PAX6	1.90e-05	11	21	2	18562598
Pubmed	Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.	CREB5 PAX6	1.90e-05	11	21	2	23638021
Pubmed	AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis.	POU4F2 PAX6	2.28e-05	12	21	2	20150232
Pubmed	Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression.	PRKCI PAX6	2.28e-05	12	21	2	25916881
Pubmed	Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex.	TLE3 PAX6	2.28e-05	12	21	2	20348416
Pubmed	The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.	PRKCI PAX6	2.28e-05	12	21	2	22031545
Pubmed	Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits.	POU4F2 PAX6	2.28e-05	12	21	2	20949055
Pubmed	Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.	POU4F2 PAX6	2.28e-05	12	21	2	23649630
Pubmed	Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.	TLE3 PAX6	2.70e-05	13	21	2	22735158
Pubmed	Retinoic acid from the meninges regulates cortical neuron generation.	PRKCI PAX6	2.70e-05	13	21	2	19879845
Pubmed	The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.	POU4F2 PAX6	2.70e-05	13	21	2	19081073
Pubmed	Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease.	POU4F2 PAX6	3.15e-05	14	21	2	37126314
Pubmed	Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type.	POU4F2 PAX6	3.15e-05	14	21	2	15733660
Pubmed	Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina.	POU4F2 PAX6	3.15e-05	14	21	2	17480014
Pubmed	Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.	TLE3 PAX6	3.15e-05	14	21	2	17202186
Pubmed	Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.	POU4F2 PAX6	3.15e-05	14	21	2	14625556
Pubmed	Cell-autonomous involvement of Mab21l1 is essential for lens placode development.	POU4F2 PAX6	3.15e-05	14	21	2	12642482
Pubmed	Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.	PRKCI PAX6	3.15e-05	14	21	2	24859200
Pubmed	Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina.	POU4F2 PAX6	3.63e-05	15	21	2	15604100
Pubmed	SWI/SNF complexes are required for retinal pigmented epithelium differentiation and for the inhibition of cell proliferation and neural differentiation programs.	POU4F2 PAX6	4.15e-05	16	21	2	37522516
Pubmed	BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons.	POU4F2 PAX6	4.15e-05	16	21	2	19339595
Pubmed	An entosis-like process induces mitotic disruption in Pals1 microcephaly pathogenesis.	PRKCI PAX6	4.70e-05	17	21	2	36604424
Pubmed	A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis.	POU4F2 PAX6	4.70e-05	17	21	2	38823017
Pubmed	Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.	POU4F2 PAX6	4.70e-05	17	21	2	15797020
Pubmed	Math5 determines the competence state of retinal ganglion cell progenitors.	POU4F2 PAX6	4.70e-05	17	21	2	14623245
Pubmed	Math5 is required for retinal ganglion cell and optic nerve formation.	POU4F2 PAX6	4.70e-05	17	21	2	11493566
Pubmed	Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina.	POU4F2 PAX6	4.70e-05	17	21	2	23197712
Pubmed	Atoh7-independent specification of retinal ganglion cell identity.	POU4F2 PAX6	4.70e-05	17	21	2	33712461
Pubmed	Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.	POU4F2 PAX6	5.28e-05	18	21	2	18987029
Pubmed	Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.	POU4F2 PAX6	5.28e-05	18	21	2	25794677
Pubmed	Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice.	POU4F2 PAX6	5.28e-05	18	21	2	17166916
Pubmed	The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development.	POU4F2 PAX6	5.90e-05	19	21	2	16182275
Pubmed	Msx1-Positive Progenitors in the Retinal Ciliary Margin Give Rise to Both Neural and Non-neural Progenies in Mammals.	POU4F2 PAX6	5.90e-05	19	21	2	28011038
Pubmed	ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.	PRKCI PAX6	5.90e-05	19	21	2	20619750
Pubmed	SOX2 is a dose-dependent regulator of retinal neural progenitor competence.	POU4F2 PAX6	5.90e-05	19	21	2	16651659
Pubmed	Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.	POU4F2 PAX6	6.55e-05	20	21	2	20696379
Pubmed	Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina.	POU4F2 PAX6	6.55e-05	20	21	2	16026391
Pubmed	Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.	POU4F2 PAX6	6.55e-05	20	21	2	19088125
Pubmed	Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.	PRKCI PAX6	6.55e-05	20	21	2	27616714
Pubmed	Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development.	POU4F2 PAX6	7.24e-05	21	21	2	20969844
Pubmed	Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1.	POU4F2 PAX6	7.24e-05	21	21	2	19692620
Pubmed	ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.	PRKCI PAX6	7.24e-05	21	21	2	38402586
Pubmed	Onecut1 is essential for horizontal cell genesis and retinal integrity.	POU4F2 PAX6	7.24e-05	21	21	2	23926259
Pubmed	Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity.	POU4F2 PAX6	7.24e-05	21	21	2	25995483
Pubmed	Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.	POU4F2 PAX6	7.24e-05	21	21	2	17559664
Pubmed	Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.	POU4F2 PAX6	7.24e-05	21	21	2	27385012
Pubmed	Multiple requirements for Hes 1 during early eye formation.	POU4F2 PAX6	7.96e-05	22	21	2	16038893
Pubmed	The apical complex couples cell fate and cell survival to cerebral cortical development.	PRKCI PAX6	7.96e-05	22	21	2	20399730
Pubmed	Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.	POU4F2 PAX6	7.96e-05	22	21	2	29249622
Pubmed	m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina.	PAX6 BCL7A	7.96e-05	22	21	2	36459087
Pubmed	Lim1 is essential for the correct laminar positioning of retinal horizontal cells.	POU4F2 PAX6	7.96e-05	22	21	2	18094249
Pubmed	Pten coordinates retinal neurogenesis by regulating Notch signalling.	POU4F2 PAX6	7.96e-05	22	21	2	22258620
Pubmed	Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.	POU4F2 PAX6	7.96e-05	22	21	2	18460603
Pubmed	PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus.	PRKCI PAX6	7.96e-05	22	21	2	22705452
Pubmed	MATH5 controls the acquisition of multiple retinal cell fates.	POU4F2 PAX6	7.96e-05	22	21	2	21087508
Pubmed	PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.	PRKCI PAX6	8.72e-05	23	21	2	31504280
Pubmed	Cd9 Protects Photoreceptors from Injury and Potentiates Edn2 Expression.	POU4F2 PAX6	8.72e-05	23	21	2	32150249
Pubmed	Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.	POU4F2 PAX6	8.72e-05	23	21	2	25966682
Pubmed	The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.	PRKCI PAX6	9.51e-05	24	21	2	16892058
Pubmed	Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.	POU4F2 PAX6	9.51e-05	24	21	2	19416500
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	POU4F2 PAX6	9.51e-05	24	21	2	20826655
Pubmed	Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina.	POU4F2 PAX6	9.51e-05	24	21	2	17092954
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KAT6B FOXO3 FOXJ3 TLE3 PAX6	9.98e-05	808	21	5	20412781
Pubmed	GDF11 controls the timing of progenitor cell competence in developing retina.	POU4F2 PAX6	1.03e-04	25	21	2	15976303
Pubmed	Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate.	POU4F2 PAX6	1.03e-04	25	21	2	25775587
Pubmed	Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity.	POU4F2 PAX6	1.03e-04	25	21	2	33795534
Pubmed	Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina.	POU4F2 PAX6	1.03e-04	25	21	2	22411557
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	KAT6B SLC31A1 TLE3 PAX6	1.11e-04	424	21	4	21731673
Pubmed	The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.	POU4F2 PAX6	1.12e-04	26	21	2	27697904
Pubmed	miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression.	POU4F2 PAX6	1.12e-04	26	21	2	21857657
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KAT6B PAX6 BCL7A	1.13e-04	157	21	3	30186101
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SCN10A FOXJ3 USF3 YLPM1	1.17e-04	430	21	4	35044719
Pubmed	Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.	POU4F2 PAX6	1.21e-04	27	21	2	22323600
Pubmed	BMP receptor 1b is required for axon guidance and cell survival in the developing retina.	POU4F2 PAX6	1.21e-04	27	21	2	12654290
Pubmed	Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice.	POU4F2 PAX6	1.21e-04	27	21	2	28579317
Pubmed	An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.	POU4F2 PAX6	1.40e-04	29	21	2	23652001
Pubmed	Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.	CREB5 PAX6	1.40e-04	29	21	2	29543863
Cytoband	1p34.2	FOXJ3 CFAP57	3.13e-04	57	21	2	1p34.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1p34	FOXJ3 CFAP57	7.92e-03	294	21	2	chr1p34
GeneFamily	Forkhead boxes	FOXO3 FOXJ3	7.35e-04	43	17	2	508
GeneFamily	WD repeat domain containing	TLE3 CFAP57	2.47e-02	262	17	2	362
Computational	Genes in the cancer module 200.	POU4F2 PAX6	7.13e-04	27	16	2	MODULE_200
Computational	Genes in the cancer module 80.	POU4F2 PAX6	1.00e-03	32	16	2	MODULE_80
Computational	Genes in the cancer module 51.	POU4F2 PAX6	1.27e-03	36	16	2	MODULE_51
Disease	venous thromboembolism	MAP3K21 TLE3 MIPEP BCL7A	2.83e-04	460	21	4	EFO_0004286
Disease	TPE interval measurement	SCN10A CREB5	6.26e-04	52	21	2	EFO_0004644
Disease	isoleucine measurement	CFAP57 MIPEP	7.26e-04	56	21	2	EFO_0009793
Disease	atrial fibrillation	SCN10A CREB5 TLE3	2.22e-03	371	21	3	EFO_0000275
Disease	neurotic disorder	PAX6 YLPM1	2.33e-03	101	21	2	EFO_0004257
Disease	Alloxan Diabetes	FOXO3 PAX6	2.66e-03	108	21	2	C0002152
Disease	Streptozotocin Diabetes	FOXO3 PAX6	2.66e-03	108	21	2	C0038433
Disease	Diabetes Mellitus, Experimental	FOXO3 PAX6	2.66e-03	108	21	2	C0011853

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSHMMASMLSNLDHS	ADAMTS1	426	Q9UHI8
SMSQPMMNSGYHSNH	KAT6B	1996	Q8WYB5
HMQTHMNSQPMGTSG	PAX6	376	P26367
THHPAAMSNGNMNTM	CREB5	241	Q02930
MPMDQSSMHSDHAQT	PRKCI	201	P41743
MVAASSHSQMSMPQV	CFAP57	271	Q96MR6
HQASEKDMMHSASSP	IL12RB2	736	Q99665
DMSMNMLPPNHSSDF	MED4	226	Q9NPJ6
TTMAGHHRAMNQQHM	FOXJ3	581	Q9UPW0
NMNDTMVSHMSSGVP	DTNB	341	O60941
SSSPGMMDMHDDNSN	BCL7A	81	Q4VC05
HMGMSYMDSNSTMQP	SLC31A1	6	O15431
HSDVMMTQSDPLMSQ	FOXO3	481	O43524
ITPDSSHQNRHAMMM	BMT2	276	Q1RMZ1
MTEMPQESFHSMQDD	MAP3K21	406	Q5TCX8
HMATMNPMHQAALSM	POU4F2	221	Q12837
TPSMMENLFHEMGHA	MIPEP	486	Q99797
FMAMEHHGMSPTFEA	SCN10A	681	Q9Y5Y9
PPMHMTNSHLSNFNM	USF3	2176	Q68DE3
FAMMSHHEMNGSLTS	TLE3	371	Q04726
MAEHMPSSHHSSEMM	YLPM1	1416	P49750
HTPDSRMAHTMIMQD	ZNF711	11	Q9Y462