Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of intracellular transport	ARHGAP1 RANGAP1 ABCA2 DERL3	4.74e-06	61	38	4	GO:0032387
GeneOntologyBiologicalProcess	central nervous system myelin formation	ERCC2 ABCA2	1.18e-04	9	38	2	GO:0032289
GeneOntologyBiologicalProcess	regulation of cholesterol metabolic process	ABCA2 ARV1 SERPINA12	1.27e-04	53	38	3	GO:0090181
GeneOntologyBiologicalProcess	regulation of intracellular sterol transport	ABCA2 ARV1	2.16e-04	12	38	2	GO:0032380
GeneOntologyBiologicalProcess	regulation of intracellular cholesterol transport	ABCA2 ARV1	2.16e-04	12	38	2	GO:0032383
GeneOntologyBiologicalProcess	regulation of intracellular lipid transport	ABCA2 ARV1	2.55e-04	13	38	2	GO:0032377
GeneOntologyBiologicalProcess	regulation of intracellular transport	ARHGAP1 RANGAP1 ABCA2 ARV1 DERL3	2.63e-04	314	38	5	GO:0032386
Domain	UBIQUITIN_1	SACS UBLCP1	2.43e-03	37	37	2	PS00299
Domain	ubiquitin	SACS UBLCP1	3.90e-03	47	37	2	PF00240
Domain	UBIQUITIN_2	SACS UBLCP1	5.12e-03	54	37	2	PS50053
Domain	Ubiquitin_dom	SACS UBLCP1	5.89e-03	58	37	2	IPR000626
Pubmed	Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.	TSHR SLC16A2	1.16e-06	2	38	2	29290039
Pubmed	The Amino Acid Transporter Mct10/Tat1 Is Important to Maintain the TSH Receptor at Its Canonical Basolateral Localization and Assures Regular Turnover of Thyroid Follicle Cells in Male Mice.	TSHR SLC16A2	6.96e-06	4	38	2	34071318
Pubmed	The chromosomal distribution of mouse odorant receptor genes.	OR8A1 SAG ZP2	2.87e-05	54	38	3	8570653
Pubmed	Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea.	TSHR SLC16A2	5.20e-05	10	38	2	21878515
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	DOCK7 DBT GCN1 PLBD2	8.12e-05	210	38	4	26217791
Pubmed	Myosin-X recruits lamellipodin to filopodia tips.	RANGAP1 SACS GCN1	1.28e-04	89	38	3	36861887
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DOCK7 RANGAP1 DBT MED23 SACS GCN1 RCL1	1.50e-04	1082	38	7	38697112
Pubmed	The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.	TSHR SLC16A2	2.18e-04	20	38	2	24265449
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TUBGCP6 PPP4R3B RANGAP1 ABCA2 MED23	2.65e-04	529	38	5	14621295
Pubmed	Regulation of planar cell polarity by Smurf ubiquitin ligases.	PRICKLE1 SMURF2	3.43e-04	25	38	2	19379695
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	GPD1L ARHGAP1 RANGAP1 SLC16A2 GCN1 UBLCP1	3.52e-04	878	38	6	37223481
Pubmed	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	ZBTB40 ARHGAP1	4.01e-04	27	38	2	19801982
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	ARHGAP1 RANGAP1 GCN1 UBLCP1 PLBD2 SERPINA12 RCL1	6.18e-04	1367	38	7	32687490
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP4R3B ARHGAP1 RANGAP1 DBT GCN1 UBLCP1	8.97e-04	1049	38	6	27880917
Interaction	TSPAN8 interactions	ARV1 SERPINA12 TMEM161B FAM210B	1.06e-05	75	37	4	int:TSPAN8
Interaction	FOXJ3 interactions	RANGAP1 MED23 SERPINA12	4.24e-05	37	37	3	int:FOXJ3
Interaction	SCN3B interactions	MED23 ARV1 ALG6 GCN1 PLBD2	4.26e-05	214	37	5	int:SCN3B
Cytoband	1p31.3	DOCK7 ALG6	8.29e-04	51	38	2	1p31.3
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	BAIAP3 SMURF2	9.50e-04	36	23	2	823
Disease	sulfate measurement	SLC13A1 UBLCP1	1.38e-04	14	37	2	EFO_0007864
Disease	feeling tense measurement	RANGAP1 TMEM161B	7.88e-04	33	37	2	EFO_0009596
Disease	left ventricular ejection fraction measurement	DEFB136 DERL3	1.16e-03	40	37	2	EFO_0008373
Disease	bitter beverage consumption measurement	RANGAP1 TMEM161B	1.28e-03	42	37	2	EFO_0010089

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFLKDGKLKLSLFQP	CNTNAP3	421	Q9BZ76
LLLKCLGKLQLFQPS	BAIAP3	536	O94812
LILQPSSKGFKFTLV	ALG6	316	Q9Y672
KFPLISTLKKALGLQ	CHIA	376	Q9BZP6
LLKKLGSNTYPFLLT	SAG	111	P10523
KRLLQTPGFLKLLLD	DERL3	196	Q96Q80
IPGLKKIYLQVLSFL	SLC16A2	381	P36021
VLKATALPLLKQFGI	RCL1	131	Q9Y2P8
FPKALAPLLLAFVTK	RANGAP1	551	P46060
FLKSFLPLKTGLLIA	SDR16C5	276	Q8N3Y7
FLKAASLGLLQFPIL	DBT	311	P11182
ILKQKGLLDKFPLFT	GPD1L	311	Q8N335
PAILLKLGFKESLVQ	FAM210B	126	Q96KR6
IKGFISQLLPTVFKS	MED23	581	Q9ULK4
KLPFLGLALSSRKNL	ERCC2	101	P18074
PPTLSLLTIGFLFKK	TUBGCP6	451	Q96RT7
SLLLAKVGIALKPFL	GCN1	2331	Q92616
FKTLAKLGILPALEI	PPP4R3B	356	Q5MIZ7
QLLSKLKGFLFQLCP	MTERF2	246	Q49AM1
TQLLLKFGDKSLFQP	PRICKLE1	416	Q96MT3
FLQTLTGRLPTKKLF	DOCK7	971	Q96N67
KALLLSSYGKLLLIP	ARV1	181	Q9H2C2
KLPKALFIGLTLAIA	GALNT8	6	Q9NY28
FFILLGLRQKKPTIS	ABCA2	36	Q9BZC7
SALLFFLVILLPSGK	DEFB136	6	Q30KP8
LIGLLFFLIPAKTLT	SLC13A1	391	Q9BZW2
FLGLLKKPTVDLVIN	SACS	2281	Q9NZJ4
LKGLTKRADLQLPLF	OR8A1	31	Q8NGG7
LKNIFTPLLFRGLLS	TMEM161B	446	Q8NDZ6
LILFKPLISFKFGQK	ARHGAP1	171	Q07960
TLPLIGKLLKFQLLQ	SPAG17	121	Q6Q759
LAVLLTVKGLLKPSF	SERPINA12	11	Q8IW75
LPFYKQLLGKSITLD	SMURF2	506	Q9HAU4
LDLKQFLKTLTGVLP	UBLCP1	26	Q8WVY7
KFTIKPLGFLLLQLS	PLBD2	206	Q8NHP8
SLKLTFISPGQKVIF	ZP2	241	Q05996
TTFPNLGLLLEKLQK	ZBTB40	431	Q9NUA8
ALKELPLLKFLGIFN	TSHR	121	P16473