RIPK3 TRIO PDK4 STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK PIK3CA FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

ROR1 SRC RET LCK TEC YES1 RYK FER KIT EPHA10 DYRK2

RIPK3 TRIO PDK4 STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK PIK3CA FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 TRIO PDK4 STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK PIK3CA FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 TRIO PDK4 STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK PIK3CA FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

SRC LCK TEC YES1 FER

ROR1 RET RYK KIT EPHA10

ROR1 RYK FZD5

ROR1 RET RYK KIT EPHA10

RIPK3 TRIO STK17A LMTK2 CAMK1 PIK3CA MAP3K10 MAP3K21 DYRK2

PDK4 ESR2 ROR1 SRC LMTK2 RET LCK YES1 SVEP1 RYK STAT5A STAT5B CUL5 GHSR MYOF PIK3CA FER HRG RABGEF1 BAIAP2 KIT EPHA10

FER RABGEF1 KIT

FER RABGEF1 KIT

FER RABGEF1 KIT

TRIO PDK4 ESR2 ROR1 SRC LMTK2 RET LCK YES1 SVEP1 RYK STAT5A STAT5B CUL5 GHSR MYOF PIK3CA FER HRG RABGEF1 BAIAP2 KIT EPHA10

RIPK3 ROR1 SRC CAMK1 RET RYK PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

HTR1B PDK4 ESR2 SRC CPN1 CCKAR STAT5A STAT5B PHEX GHSR OTC GTF2H1 ARSB PLPP1 PIK3CA FER BAIAP2 PADI2 NPAS4

THEMIS RIPK3 CHD7 LCK STAT5A STAT5B KLHL25 FZD5 BTN2A3P SEMA4A KIT

THEMIS RIPK3 CHD7 LCK CR2 STAT5A STAT5B KLHL25 FZD5 BTN2A3P SEMA4A KIT HECTD1

THEMIS SRC LCK TEC CR2 YES1 PIK3CA BTN2A3P FER RABGEF1 KIT

SRC LCK YES1 FER KIT

PDK4 ESR2 SRC CCKAR STAT5A STAT5B PHEX GHSR GTF2H1 PLPP1 PIK3CA FER BAIAP2 PADI2 NPAS4

LCK STAT5A STAT5B

RIPK3 ROR1 SRC CAMK1 RET RYK PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

ROR1 SRC OBSL1 CAMK1 RET ARSB PIK3CA RAB3IP NEURL1 AFDN BAIAP2 KIT

RET STAT5A STAT5B

RET STAT5A STAT5B

KCTD19 SMCHD1 ESR2 SRC CHD7 DNAAF11 CFAP43 RNF17 ZNF595 STAT5A STAT5B GHSR PIK3CA FZD5 NEURL1 CCDC87 FER PLG KIT HECTD1

LCK STAT5A STAT5B

RIPK3 SRC LMTK2 LCK FER MAP3K10 MAP3K21 KIT

THEMIS RIPK3 SRC CHD7 LCK TEC CR2 YES1 SVEP1 STAT5A STAT5B KLHL25 PIK3CA FZD5 BTN2A3P FER HRG RABGEF1 SEMA4A KIT HECTD1

LCK STAT5A STAT5B

SRC LCK TEC F11 SVEP1 STAT5A STAT5B PIK3CA NEURL1 HRG PLG

GHSR KIT

STAT5A STAT5B

RIPK3 SRC RET LCK YES1 STAT5B FER RABGEF1 PLG KIT PADI2

STAT5A STAT5B PHEX GHSR

THEMIS RIPK3 SRC CHD7 LCK YES1 STAT5A STAT5B KLHL25 PIK3CA FZD5 BTN2A3P SEMA4A KIT

LCK STAT5A STAT5B

DNAH2 DNAAF11 DNAAF1

THEMIS RIPK3 CHD7 LCK CR2 STAT5A STAT5B KLHL25 FZD5 BTN2A3P SEMA4A KIT HECTD1

CHD7 STAT5A STAT5B GHSR

STAT5B RABGEF1 KIT

PDK4 SRC PIK3CA

F11 HRG PLG

SRC LCK YES1 STAT5A NEURL1 FER HRG KIT DYRK2

SRC LCK YES1 STAT5A NEURL1 FER HRG KIT DYRK2

SRC LCK TEC F11 SVEP1 PIK3CA HRG PLG

RET LCK STAT5A STAT5B FER OCIAD2 KIT

LCK STAT5A STAT5B

ROR1 SRC OBSL1 CAMK1 RET RYK ARSB PIK3CA RAB3IP NEURL1 FER HRG AFDN BAIAP2 KIT

NEXMIF FER AFDN PLG

SRC LCK TEC F11 SVEP1 PIK3CA HRG PLG

RIPK3 SRC LCK TEC YES1 SVEP1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P FER HRG RABGEF1

SRC LCK TEC F11 SVEP1 PIK3CA HRG PLG

SRC LCK YES1 PIK3CA

NEXMIF AFDN PLG

CHD7 STAT5A STAT5B GHSR PIK3CA

ROR1 SRC OBSL1 CAMK1 RET RYK ARSB PIK3CA RAB3IP NEURL1 FER HRG AFDN BAIAP2 KIT

SRC LCK YES1 PIK3CA

RIPK3 SRC CAMK1 PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

RIPK3 STAT5A STAT5B BTN2A3P

RIPK3 ROR1 SRC CAMK1 RET RYK GTF2H1 PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

RIPK3 ROR1 SRC CAMK1 RET LCK YES1 RYK PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

GHSR KIT

F11 PLG

SRC RET OTC FZD5 DNAAF1 KIT

THEMIS RIPK3 SRC CHD7 LCK CR2 YES1 STAT5A STAT5B KLHL25 PIK3CA FZD5 BTN2A3P SEMA4A KIT HECTD1

SRC PIK3CA FER HRG KIT

THEMIS RIPK3 SRC CHD7 LCK CR2 YES1 STAT5A STAT5B KLHL25 PIK3CA FZD5 BTN2A3P FER RABGEF1 SEMA4A KIT HECTD1

RET LCK STAT5A STAT5B FER OCIAD2 KIT

THEMIS RIPK3 SRC CHD7 LCK CR2 STAT5A STAT5B KLHL25 FZD5 BTN2A3P SEMA4A KIT HECTD1

THEMIS RIPK3 SRC LCK TEC CR2 YES1 SVEP1 STAT5A STAT5B PIK3CA FZD5 BTN2A3P FER HRG RABGEF1 KIT

THEMIS SRC LCK TEC CR2 YES1 PIK3CA BTN2A3P RABGEF1

SRC PIK3CA FER HRG

ESR2 SRC CHD7 STAT5A STAT5B KIT

SRC LCK TEC SVEP1 PIK3CA HRG

SRC LCK YES1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P

RIPK3 ROR1 SRC CAMK1 RET RYK GTF2H1 PIK3CA FZD5 HPF1 NEURL1 MAP3K10 KIF14 KIT

PDK4 SRC PIK3CA

GHSR KIT

STAT5A KIT

RIPK3 NEXMIF SRC RET RYK STAT5A STAT5B GHSR ARSB PGAM4 FER KIF14 HRG AFDN RABGEF1 SEMA4A PLG KIT PADI2

DNAH2 DNAAF11 CFAP43 NEURL1 DNAAF1

RIPK3 ROR1 SRC CAMK1 RET LCK YES1 RYK GTF2H1 PIK3CA FZD5 NEURL1 FER MAP3K10 KIF14 HRG RABGEF1 KIT

STAT5A STAT5B GHSR

SRC RET OTC FZD5 DNAAF1 KIT

BRINP3 HTR1B PDK4 ESR2 SRC CPN1 RET CR2 YES1 STAT5B PHEX GHSR PLPP1 PIK3CA FER PADI2 NPAS4

HTR1B ESR2 SRC CPN1 GHSR PLPP1 PIK3CA PADI2 NPAS4

NEXMIF SRC RET LCK YES1 STAT5A STAT5B KLHL25 LMO7 PIK3CA BTN2A3P KIF14 HRG AFDN PLG

RIPK3 STAT5A STAT5B BTN2A3P

RIPK3 CR2 SVEP1 STAT5A STAT5B FZD5 RABGEF1 KIT

SRC LCK YES1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P AFDN

F11 HRG PLG

GHSR KIT

THEMIS SRC LCK TEC CR2 YES1 SVEP1 STAT5A STAT5B PIK3CA FZD5 BTN2A3P HRG RABGEF1

SRC LCK YES1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P

SRC YES1 FER

CAMK1 NEURL1 AFDN BAIAP2

SRC PIK3CA RAB3IP NEURL1 FER HRG KIT

SRC RET LCK YES1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P HRG AFDN

NEXMIF SRC LCK YES1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P AFDN PLG

DNAAF11 RAB3IP

CR2 SVEP1

STAT5A KIT

HTR1B SRC CPN1 GHSR PIK3CA NPAS4

NEXMIF SRC RET LCK YES1 SVEP1 STAT5A STAT5B KLHL25 PIK3CA BTN2A3P FER AFDN BAIAP2 PLG KIT

LCK STAT5A STAT5B

RIPK3 ROR1 SRC CAMK1 RET LCK YES1 RYK PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

RIPK3 ROR1 SRC CAMK1 RET LCK YES1 RYK PIK3CA FZD5 NEURL1 MAP3K10 KIF14 KIT

RAB3IP RAB3IL1

THEMIS OBSL1 LCK TEC GJA9 LMO7 PIK3CA FZD5 FER AFDN BAIAP2 KIT

SRC LCK YES1 BAIAP2

CPN1 MYOF PLG KIT

ROR1 SRC LMTK2 RET LCK TEC YES1 RYK FER MAP3K10 MAP3K21 KIT EPHA10

ROR1 SRC LMTK2 RET LCK TEC YES1 RYK FER MAP3K10 MAP3K21 KIT EPHA10

ROR1 SRC RET LCK TEC YES1 RYK FER MAP3K21 KIT EPHA10

ROR1 SRC RET LCK TEC YES1 RYK FER MAP3K21 KIT EPHA10

ROR1 SRC LMTK2 RET LCK TEC YES1 RYK FER KIT EPHA10

ROR1 SRC LMTK2 RET LCK TEC YES1 RYK FER KIT EPHA10

RIPK3 TRIO STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 TRIO STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK PIK3CA FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 TRIO STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 TRIO STK17A ROR1 SRC LMTK2 CAMK1 RET LCK TEC YES1 RYK FER MAP3K10 MAP3K21 KIT EPHA10 DYRK2

RIPK3 STK17A SRC LMTK2 CAMK1 RET LCK TEC YES1 FER MAP3K10 MAP3K21 KIT DYRK2

SRC LCK TEC YES1 STAT5A STAT5B FER

SRC LCK TEC YES1 STAT5A STAT5B FER

SRC LCK TEC YES1 STAT5A STAT5B FER

SRC LCK TEC YES1 STAT5A STAT5B FER

SRC LCK TEC YES1 STAT5A STAT5B FER

RAB3IP RAB3IL1

RAB3IP RAB3IL1

TRIO SRC LCK TEC YES1 MAP3K10 BAIAP2 MAP3K21

TRIO SRC LCK TEC YES1 MAP3K10 BAIAP2 MAP3K21

TRIO SRC LCK TEC YES1 MAP3K10 MAP3K21

TRIO SRC LCK TEC YES1 MAP3K10 BAIAP2 MAP3K21

MAP3K10 MAP3K21

MAP3K10 MAP3K21

CHD3 CHD7 CBX5

CHD3 CHD7 CBX5

CHD3 CHD7 CBX5

CHD3 CHD7 CBX5

STAT5A STAT5B

STAT5A STAT5B

F11 PLG

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

F11 PLG

STAT5A STAT5B

F11 PLG

STAT5A STAT5B

CHD3 CHD7 CBX5

CHD3 CHD7 CBX5

CHD3 CHD7 CBX5

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

DNAH3 DNAH2

TRIM4 CHD3 RNF17 KMT2C NEURL1 SCAF11 ARIH1

IRF6 KIF14 AFDN

TRIO ROR1 OBSL1 SIGLEC5 LRIG3 KIT

TRIO ROR1 OBSL1 SIGLEC5 LRIG3 KIT

ROR1 PLG

ROR1 PLG

ROR1 PLG

ROR1 PLG

ROR1 PLG

ROR1 PLG

CHD3 CBX5

SRC LCK TEC YES1 STAT5A STAT5B PIK3CA FER KIT

SRC LCK YES1 STAT5A STAT5B PIK3CA KIT

SRC LCK YES1 STAT5A STAT5B PIK3CA FER KIT

SRC LCK TEC YES1 STAT5A STAT5B PIK3CA

SRC LCK YES1 STAT5A STAT5B PIK3CA FER

SRC LCK YES1 KIT

SRC LCK YES1 KIT

LCK STAT5A STAT5B PIK3CA

LCK STAT5A STAT5B PIK3CA

SRC LCK YES1 STAT5A STAT5B PIK3CA AFDN BAIAP2

SRC TEC YES1 STAT5A STAT5B KIT

SRC YES1 LMO7 FER AFDN BAIAP2

TEC YES1 STAT5A STAT5B PIK3CA

TEC STAT5A PIK3CA FER KIT

SRC STAT5A STAT5B PIK3CA

LCK STAT5A STAT5B

SRC STAT5A STAT5B PIK3CA

SRC STAT5A STAT5B PIK3CA PLG

SRC LCK YES1 PIK3CA

LCK STAT5A STAT5B PIK3CA

SRC STAT5A STAT5B PIK3CA PLG

SRC TEC STAT5A STAT5B KIT

SRC LCK YES1

LCK STAT5A STAT5B

SRC LCK YES1

TRIO SRC YES1 PIK3CA

SRC LCK YES1 PIK3CA

SRC LCK TEC STAT5A STAT5B PIK3CA

SRC LCK YES1 STAT5A STAT5B PIK3CA

SRC LCK YES1 PIK3CA

LCK STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

LCK STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

YES1 STAT5A STAT5B PIK3CA

SRC LCK YES1 PLG

SRC LCK PIK3CA

SRC TEC STAT5A STAT5B PIK3CA

SRC STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

SRC YES1 EPHA10

LCK STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

ESR2 SRC LCK PIK3CA KIT

SRC LCK YES1 PIK3CA

STAT5A STAT5B PIK3CA PLG

SRC LCK YES1

SRC LCK YES1

SRC YES1 CUL5 PIK3CA

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

LCK STAT5A STAT5B

SRC LCK TEC YES1 STAT5A STAT5B CUL5 PIK3CA FER BAIAP2 PLG KIT

SRC YES1 PIK3CA

LCK STAT5A STAT5B

STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

ESR2 SRC LCK YES1 STAT5A STAT5B LMO7 PIK3CA FZD5 NEURL1 KIT

STAT5A STAT5B PIK3CA

LCK STAT5A STAT5B PIK3CA

STAT5A STAT5B

SRC PIK3CA

STAT5A STAT5B

STAT5A STAT5B CUL5

STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA KIT

SRC STAT5A STAT5B

SRC STAT5A STAT5B

STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA

SRC LCK YES1

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B

STAT5A STAT5B PIK3CA

SRC LCK YES1 STAT5A STAT5B PIK3CA FER BAIAP2 PLG KIT

ZNF141 CHD3 ZNF519 CBX5 ZNF264

STAT5A STAT5B PIK3CA

SRC YES1 EPHA10

ESR2 SRC LCK PIK3CA KIT

STAT5A STAT5B CUL5

SRC LCK YES1

SRC PIK3CA AFDN

SRC CAMK1 STAT5A FZD5

SRC LCK YES1 PIK3CA

PIK3CA KIT

SRC PIK3CA

RET PIK3CA

STAT5A STAT5B PIK3CA

SRC YES1 PIK3CA

ESR2 SRC LCK PIK3CA KIT

SRC STAT5A STAT5B PIK3CA

STAT5A STAT5B PIK3CA KIT

SRC LCK YES1

CHD7 YES1 FZD5

SRC YES1 PIK3CA BAIAP2

The protein tyrosine kinase family of the human genome.

ROR1 SRC RET LCK TEC YES1 RYK FER KIT

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation.

SRC LCK YES1 KIT

Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells.

SRC LCK YES1 KIT

Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.

SRC LCK YES1 KIT

Substrate-trapping techniques in the identification of cellular PTP targets.

SRC RET TEC YES1 STAT5A STAT5B

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO LMTK2 LCK USP31 IPO9 LMO7 NEURL1 MAP3K10 KIF14 AFDN RABGEF1 BAIAP2 MAP3K21 HECTD1 OTOG DYRK2

STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation.

LCK STAT5A STAT5B

STAT protein recruitment and activation in c-Kit deletion mutants.

STAT5A STAT5B KIT

A STAT5 modifier locus on murine chromosome 7 modulates engraftment of hematopoietic stem cells during steady-state hematopoiesis.

STAT5A STAT5B KIT

Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells.

SRC TEC YES1 KIT

Phospho-tyrosine dependent protein-protein interaction network.

SRC OBSL1 CAMK1 LCK YES1 STAT5A KMT2C PIK3CA CCDC87 FER BAIAP2

Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation.

LCK STAT5A STAT5B

PTPN2 regulates T cell lineage commitment and αβ versus γδ specification.

LCK STAT5A STAT5B

Direct interaction between Kit and the interleukin-7 receptor.

STAT5A STAT5B KIT

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

HAUS6 MYO19 OBSL1 C15orf39 DNAAF11 NXN URGCP GTF2H1 IPO9 LMO7 CDC16 RAB3IP AFDN RABGEF1 BAIAP2 DNAAF1 MAP3K21 RAB3IL1 DYRK2

FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.

SRC RET LCK YES1

Stat5 expression is critical for mast cell development and survival.

STAT5A STAT5B KIT

Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors.

SRC LCK YES1

Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.

SRC LCK YES1

Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates.

STAT5A STAT5B KIT

Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases.

SRC LCK YES1

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress.

SRC LCK YES1

p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction.

SRC YES1 FER

Phosphorylation of SOCS1 Inhibits the SOCS1-p53 Tumor Suppressor Axis.

SRC LCK YES1

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TRIO SRC CHD3 NXN LIN52 ZNF595 STAT5B CUL5 RLF KMT2C FAM120A PLPP1 RAB3IP SCAF11 BAIAP2 ARIH1 HECTD1 NBR1 MOCOS

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

SRC LCK YES1 PHEX

Murine txk: a protein tyrosine kinase gene regulated by T cell activation.

SRC TEC RYK KIT

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EEFSEC MYO19 PARG OBSL1 C15orf39 CHD3 URGCP STAT5B CUL5 FAM120A AFDN MOCOS

JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

SRC YES1 STAT5A

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

SRC LCK TEC YES1 KIT

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

TRIO STK17A SRC OBSL1 RET LCK TEC YES1 MYOF GTF2H1 CDC16 FER MAP3K21 DYRK2

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

SRC RET LCK CUL5 GHSR PIK3CA MAP3K10 RABGEF1

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

SRC LCK TEC YES1 FER

Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.

STAT5A STAT5B

Ret-mediated mitogenesis requires Src kinase activity.

SRC RET

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

STAT5A STAT5B

Activation of phosphatidylinositol-3-kinase in Jurkat T cells depends on the presence of the p56lck tyrosine kinase.

LCK PIK3CA

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.

STAT5A STAT5B

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

STAT5A STAT5B

Recurrent inflammatory myofibroblastic tumors harboring PIK3CA and KIT mutations.

PIK3CA KIT

Familial association of high levels of histidine-rich glycoprotein and plasminogen activator inhibitor-1 with venous thromboembolism.

HRG PLG

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

STAT5A STAT5B

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.

STAT5A STAT5B

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.

STAT5A STAT5B

Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.

STAT5A STAT5B

Tyrosine Kinase Inhibition in HPV-related Squamous Cell Carcinoma Reveals Beneficial Expression of cKIT and Src.

SRC KIT

Constitutively active Stat5A and Stat5B promote adipogenesis.

STAT5A STAT5B

Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.

STAT5A STAT5B

STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.

STAT5A STAT5B

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

STAT5A STAT5B

STAT5A and STAT5B have opposite correlations with drug response gene expression.

STAT5A STAT5B

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.

STAT5A STAT5B

Fer tyrosine kinase oligomer mediates and amplifies Src-induced tumor progression.

SRC FER

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.

STAT5A STAT5B

STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.

STAT5A STAT5B

Restriction of Src activity by Cullin-5.

SRC CUL5

Smchd1 is a maternal effect gene required for genomic imprinting.

SMCHD1 KIT

The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.

STAT5A STAT5B

Stat5: an essential regulator of mast cell biology.

STAT5A STAT5B

Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.

STAT5A STAT5B

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.

STAT5A STAT5B

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.

MAP3K10 DYRK2

Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.

STAT5A STAT5B

Ouabain stimulates a Na+/K+-ATPase-mediated SFK-activated signalling pathway that regulates tight junction function in the mouse blastocyst.

SRC YES1

Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.

STAT5A STAT5B

Lck associates with and is activated by Kit in a small cell lung cancer cell line: inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1.

LCK KIT

Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice.

SRC YES1

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.

STAT5A STAT5B

The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.

STAT5A STAT5B

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

STAT5A STAT5B

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

STAT5A STAT5B

Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.

STAT5A STAT5B

In vivo identification of novel STAT5 target genes.

STAT5A STAT5B

Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.

STAT5A STAT5B

Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.

STAT5A STAT5B

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.

STAT5A STAT5B

Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.

STAT5A STAT5B

Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.

STAT5A STAT5B

The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes.

PDK4 STAT5A

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.

STAT5A STAT5B

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.

STAT5A STAT5B

Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.

STAT5A STAT5B

PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.

PIK3CA KIT

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

STAT5A STAT5B

Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.

STAT5A STAT5B

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

STAT5A STAT5B

Identification of STAT5A and STAT5B target genes in human T cells.

STAT5A STAT5B

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

STAT5A STAT5B

STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.

STAT5A STAT5B

STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.

STAT5A STAT5B

STAT5 signaling in sexually dimorphic gene expression and growth patterns.

STAT5A STAT5B

The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.

STAT5A STAT5B

MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.

STAT5A STAT5B

Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival.

SRC RET

Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.

STAT5A STAT5B

Brain STAT5 signaling modulates learning and memory formation.

STAT5A STAT5B

STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.

STAT5A STAT5B

Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.

STAT5A STAT5B

The first intestinal motility patterns in fetal mice are not mediated by neurons or interstitial cells of Cajal.

RET KIT

The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.

STAT5A STAT5B

HGH1 PDK4 MYO19 SRC DNAH2 OBSL1 CHD3 RET LCK YES1 CUL5 KMT2C FER MAP3K10 KIF14 RABGEF1 SCAF11 MAP3K21 USP48 HECTD1 NBR1

SRC LCK TEC YES1 STAT5A STAT5B PIK3CA KIT

SRC RET LCK TEC YES1 KIT

ESR2 DNAH2 OBSL1 CHD3 KIF14 SCAF11 USP48 HECTD1 NBR1

MYO19 ESR2 SRC OBSL1 LCK YES1 STAT5A STAT5B KIF14 AFDN

ESR2 SRC LCK STAT5A STAT5B CBX5 KIT

HAUS6 TRIO KIAA0586 STAT5A STAT5B IPO9 KIF14 RABGEF1

SRC TEC YES1

ESR2 SRC RET LCK STAT5A STAT5B MYOF CCDC87 FER OCIAD2 SCAF11 HECTD1

MYO19 ESR2 ROR1 OBSL1 LCK RYK KIF14 AFDN NBR1

SRC CAMK1 TEC YES1 STAT5B PIK3CA FER KIT

SRC RET LCK RYK KIF14 AFDN

RIPK3 SRC RET LCK TEC YES1 FER KIF14 AFDN

SRC YES1 STAT5A STAT5B

PDK4 ESR2 OBSL1 STAT5A STAT5B OTC KIF14 USP48 HECTD1

MYO19 ESR2 SRC OBSL1 YES1 PIK3CA KIF14 USP48

ESR2 OBSL1 CHD3 RYK ZNF263 KIF14 HECTD1 EPHA10

OBSL1 RET LCK YES1 STAT5A KIT

TRIO OBSL1 GLS

LCK STAT5A CUL5 KIT

HGH1 ESR2 ROR1 OBSL1 CHD3 KIF14 HECTD1

THEMIS SRC SIGLEC5 RET LCK RYK STAT5A STAT5B PIK3CA KIT

ESR2 RET CUL5 KIF14 RABGEF1 ARIH1 USP48 RABGGTA

ESR2 OBSL1 KIF14 AFDN HECTD1

SRC LCK TEC YES1 STAT5A STAT5B FER

ROR1 LMTK2 RET RYK KIT

TRIO CHD7 LCK TBC1D8B ARSB FZD5 FER SEMA4A USP48 KIT PADI2

HTR1B FER SEMA4A PLG PADI2 TEC MOCOS

HTR1B FER SEMA4A PLG PADI2 TEC MOCOS

ROR1 CHD7 MYOF LMO7 IL17RE BAIAP2 MOCOS

ROR1 CHD7 LMO7 IL17RE AFDN BAIAP2 MOCOS

ROR1 CHD7 MYOF LMO7 IL17RE BAIAP2 MOCOS

THEMIS ESR2 OBSL1 CFAP43 LCK OCIAD2

THEMIS STK17A ESR2 CFAP43 LCK OCIAD2

HTR1B CHD3 FER PLG PADI2 TEC

THEMIS STK17A CHD3 LCK TEC DYRK2

THEMIS STK17A CHD3 LCK TEC DYRK2

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

NEXMIF CYTL1 CPN1 CCKAR OCIAD2 MAP3K21

ESR2 MMP21 IRF6 CYTL1 NXN MYOF

NEXMIF CYTL1 CPN1 CCKAR IL17RE MAP3K21

STK17A SMCHD1 CR2 RLF GLS ARIH1

ROR1 LMTK2 MYOF LMO7 GLS AFDN

BRINP3 SLC44A1 GLS MAP3K21 KIT MOCOS

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

ESR2 IRF6 CYTL1 RET NXN OCIAD2

NEXMIF IRF6 CYTL1 NXN OCIAD2 KIT

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

NEXMIF CPN1 RET CCKAR GADL1 OCIAD2

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

DNAH3 EFCAB6 DNAH2 DNAAF11 CFAP43 DNAAF1

PDK4 IRF6 MYOF LMO7 IL17RE OCIAD2

THEMIS STK17A CHD3 LCK LMO7 OCIAD2

THEMIS STK17A CHD3 LCK LMO7 OCIAD2

STK17A LCK ZNF595 SLC44A1 OCIAD2 KIT

EFCAB6 TRIO LMTK2 COLCA1 ZNF263 SEMA4A

THEMIS STK17A CHD3 LCK STAT5B DYRK2

IRF6 OTC SULT1B1 LMO7 RAB3IP GLS

THEMIS STK17A CHD3 LCK GLS DYRK2

COLCA1 IRF6 LMO7 IL17RE OCIAD2 MAP3K21

THEMIS STK17A LCK METTL24 LMO7 OCIAD2

STK17A CYTL1 SLC44A1 OCIAD2 KIT TEC

THEMIS STK17A CHD3 LCK LMO7 OCIAD2

ROR1 LMTK2 NXN LMO7 IL17RE FZD5

STK17A CYTL1 SLC44A1 OCIAD2 KIT TEC

CHD7 RLF CDC16 MAP3K10

ROR1 OBSL1 MMP21 NXN NEURL1

RIPK3 CR2 IL17RE TPH2

RIPK3 CR2 IL17RE TPH2

PDK4 SRC CAMK1 MYOF AFDN

CPN1 RNF17 OTC TLL2 HRG

CPN1 RNF17 OTC TLL2 HRG

CPN1 RNF17 OTC TLL2 HRG

DNAH3 EFCAB6 CFAP43 LMO7 DNAAF1

LCK ARSB SEMA4A KIT PADI2

BRINP3 ZNF595 KLHL25 DNAAF1 MOCOS

CHD3 LCK STAT5A NEMP2 RAB3IP

LCK ARSB FZD5 SEMA4A PADI2

CHD3 LCK STAT5A NEMP2 RAB3IP

LCK LRIG3 ARSB SEMA4A PADI2

LCK ARSB SEMA4A USP48 PADI2

THEMIS CHD3 LCK ARSB PADI2

LCK ARSB SEMA4A KIT PADI2

LCK ARSB SEMA4A KIT PADI2

IRF6 CYTL1 RET NXN MYOF

LCK ARSB SEMA4A KIT PADI2

IRF6 CYTL1 RET NXN MYOF

STK17A ESR2 CFAP43 LCK OCIAD2

PDK4 SULT1B1 NEURL1 AFDN KIT

SRC DNAAF11 RET RYK RAB3IL1

DNAH3 EFCAB6 DNAAF11 CFAP43 DNAAF1

PDK4 SULT1B1 NEURL1 AFDN KIT

DNAH3 DNAH2 DNAAF11 CFAP43 DNAAF1

THEMIS STK17A CHD3 LCK OCIAD2

PDK4 CAMK1 YES1 KIT TEC

CYTL1 OTC IL17RE OCIAD2 PLG

ROR1 RAB3IP ARMH3 PADI2 RAB3IL1

TRIO OBSL1 LMTK2 CYTL1 KIT

ROR1 RAB3IP ARMH3 PADI2 RAB3IL1

HAUS6 THEMIS IRF6 LCK IL17RE

CPN1 F11 OTC HRG PLG

PARG RAB3IP NEURL1 ZNF264 DYRK2

THEMIS STK17A CHD3 LCK PHEX

THEMIS LCK ARSB SEMA4A PADI2

THEMIS CHD3 LCK SEMA4A PADI2

PDK4 SIGLEC5 MYOF KIF14 SEMA4A

HTR1B THEMIS LCK IL17RE SEMA4A

HTR1B THEMIS LCK IL17RE SEMA4A

HTR1B THEMIS LCK IL17RE SEMA4A

GPR179 GHSR SULT1B1 IQCM TEC

ESR2 CYTL1 NXN LMO7 FER

DNAH3 DNAH2 DNAAF11 CFAP43 DNAAF1

ROR1 MYOF LMO7 BAIAP2 MOCOS

THEMIS CHD3 LCK RAB3IP SEMA4A

ROR1 MYOF LMO7 BAIAP2 MOCOS

THEMIS STK17A LCK LMO7 OCIAD2

DNAH3 DNAH2 CFAP43 PLG DNAAF1