Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP synthase activity	CTPS2 CTPS1	2.64e-05	2	103	2	GO:0003883
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL6A3 COL12A1 VWF ACAN VCAN FGA TNXB	5.42e-05	188	103	7	GO:0005201
GeneOntologyMolecularFunction	cell adhesion molecule binding	FLNA FLNB VWF CDH23 ITGAL PTPN11 USO1 FGA MMP14 TNXB CDH8 VCL	6.05e-05	599	103	12	GO:0050839
GeneOntologyMolecularFunction	ceramide floppase activity	ABCB1 ABCB4	7.88e-05	3	103	2	GO:0099038
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCB1 ABCB4	1.57e-04	4	103	2	GO:0046623
GeneOntologyMolecularFunction	structural molecule activity	COL6A3 COL12A1 EPPK1 VWF COPA MAP2 EHHADH ACAN VCAN FGA RIMBP2 TNXB VCL	6.64e-04	891	103	13	GO:0005198
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCB1 ABCB4	7.23e-04	8	103	2	GO:0090554
GeneOntologyMolecularFunction	actin binding	MYO1G FLNA FLNB MAP2 SYNE1 SYNPO PSTPIP1 TLNRD1 VCL	8.34e-04	479	103	9	GO:0003779
GeneOntologyBiologicalProcess	regulation of nucleus organization	SYNE1 NFE2L1	2.47e-05	2	103	2	GO:1903353
GeneOntologyBiologicalProcess	'de novo' CTP biosynthetic process	CTPS2 CTPS1	2.47e-05	2	103	2	GO:0044210
GeneOntologyCellularComponent	actin filament bundle	FLNA FLNB SYNPO PSTPIP1 TLNRD1 PTPN11 VCL	1.81e-06	118	102	7	GO:0032432
GeneOntologyCellularComponent	contractile actin filament bundle	FLNB SYNPO PSTPIP1 TLNRD1 PTPN11 VCL	1.41e-05	107	102	6	GO:0097517
GeneOntologyCellularComponent	stress fiber	FLNB SYNPO PSTPIP1 TLNRD1 PTPN11 VCL	1.41e-05	107	102	6	GO:0001725
GeneOntologyCellularComponent	actomyosin	FLNB SYNPO PSTPIP1 TLNRD1 PTPN11 VCL	2.35e-05	117	102	6	GO:0042641
GeneOntologyCellularComponent	supramolecular fiber	KIF13B NES FLNA FLNB COL6A3 EPPK1 MAP2 SYNE1 INPP5D FAM161B SYNPO PSTPIP1 CTPS2 EHHADH CTPS1 VCL NIN	5.34e-05	1179	102	17	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KIF13B NES FLNA FLNB COL6A3 EPPK1 MAP2 SYNE1 INPP5D FAM161B SYNPO PSTPIP1 CTPS2 EHHADH CTPS1 VCL NIN	5.81e-05	1187	102	17	GO:0099081
GeneOntologyCellularComponent	cytoophidium	CTPS2 CTPS1	7.05e-05	3	102	2	GO:0097268
GeneOntologyCellularComponent	main axon	KIF13B MAP2 DBH MAPK8IP3 KCNH1	7.52e-05	89	102	5	GO:0044304
GeneOntologyCellularComponent	actin cytoskeleton	MYO1G FLNA FLNB MAP2 INPP5D SYNPO PSTPIP1 TLNRD1 PTPN11 VCL	5.13e-04	576	102	10	GO:0015629
GeneOntologyCellularComponent	cell-cell junction	FLNA EPPK1 SYNPO YBX3 ITGAL ABCB1 ABCB4 NPHS2 CDH8 VCL	6.25e-04	591	102	10	GO:0005911
GeneOntologyCellularComponent	intercellular canaliculus	ABCB1 ABCB4	8.30e-04	9	102	2	GO:0046581
GeneOntologyCellularComponent	perineuronal net	ACAN VCAN	1.03e-03	10	102	2	GO:0072534
GeneOntologyCellularComponent	parallel fiber to Purkinje cell synapse	PPFIA4 KCNH1 ATP2B3	1.21e-03	43	102	3	GO:0098688
GeneOntologyCellularComponent	perisynaptic extracellular matrix	ACAN VCAN	1.26e-03	11	102	2	GO:0098966
GeneOntologyCellularComponent	distal axon	FLNA COPA MAP2 DBH MAPK8IP3 RIMBP2 CDH8 NIN	1.31e-03	435	102	8	GO:0150034
GeneOntologyCellularComponent	axon	KIF13B FLNA COPA MAP2 SYNPO DBH MAPK8IP3 KCNH1 RIMBP2 ATP2B3 CDH8 NIN	1.33e-03	891	102	12	GO:0030424
GeneOntologyCellularComponent	MLL3/4 complex	KDM6B KMT2C	1.51e-03	12	102	2	GO:0044666
GeneOntologyCellularComponent	synapse-associated extracellular matrix	ACAN VCAN	1.78e-03	13	102	2	GO:0099535
HumanPheno	Spina bifida occulta	FLNA FLNB PTPN11 KCNH1 MAP3K7 TNXB	2.89e-05	77	41	6	HP:0003298
HumanPheno	Limited elbow movement	FLNA FLNB COL6A3 COL12A1 SYNE1 PSTPIP1 PTPN11 MAP3K7	4.47e-05	168	41	8	HP:0002996
HumanPheno	Accessory carpal bones	FLNA FLNB	6.32e-05	2	41	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	6.32e-05	2	41	2	HP:0008127
HumanPheno	Short diaphyses	FLNA MAP3K7	6.32e-05	2	41	2	HP:0000941
HumanPheno	Pes valgus	FLNA COL6A3 COL12A1 MAPK8IP3 MAP3K7	7.42e-05	56	41	5	HP:0008081
HumanPheno	Elbow flexion contracture	FLNA COL6A3 COL12A1 SYNE1 PSTPIP1 MAP3K7	1.07e-04	97	41	6	HP:0002987
HumanPheno	Scapular winging	FLNA FLNB COL6A3 COL12A1 SYNE1 PTPN11	1.20e-04	99	41	6	HP:0003691
HumanPheno	Abnormality of the shoulder girdle musculature	FLNA FLNB COL6A3 COL12A1 SYNE1 PTPN11 MAP3K7	1.55e-04	149	41	7	HP:0001435
HumanPheno	Abnormality of the distal phalanx of the thumb	FLNA FLNB KCNH1 MAP3K7	1.77e-04	36	41	4	HP:0009617
HumanPheno	Hypotrophy of the small hand muscles	FLNA MAP3K7	1.89e-04	3	41	2	HP:0006006
HumanPheno	Progressive bowing of long bones	FLNA MAP3K7	1.89e-04	3	41	2	HP:0006383
HumanPheno	Elbow contracture	FLNA COL6A3 COL12A1 SYNE1 PSTPIP1 MAP3K7	2.04e-04	109	41	6	HP:0034391
HumanPheno	Wrist flexion contracture	FLNA COL6A3 COL12A1 MAP3K7	2.19e-04	38	41	4	HP:0001239
HumanPheno	Mixed hearing impairment	FLNA FLNB SIX5 MAP3K7	2.68e-04	40	41	4	HP:0000410
HumanPheno	Atypical scarring of skin	FLNA COL6A3 COL12A1 MAP3K7 TNXB	2.81e-04	74	41	5	HP:0000987
HumanPheno	Subglottic stenosis	FLNA MAP3K7 NIN	3.04e-04	17	41	3	HP:0001607
HumanPheno	Eruption failure	FLNA FLNB MAP3K7	3.04e-04	17	41	3	HP:0000706
HumanPheno	Abnormality of the wrist	FLNA FLNB COL6A3 COL12A1 MMP14 MAP3K7 NIN	3.26e-04	168	41	7	HP:0003019
HumanPheno	Spina bifida	FLNA FLNB FANCM PTPN11 KCNH1 MAP3K7 TNXB	3.64e-04	171	41	7	HP:0002414
HumanPheno	Reduced muscle collagen VI	COL6A3 COL12A1	3.75e-04	4	41	2	HP:0030095
HumanPheno	Curved toe phalanx	COL6A3 COL12A1	3.75e-04	4	41	2	HP:0010176
HumanPheno	Reduced maximal expiratory pressure	COL6A3 COL12A1	3.75e-04	4	41	2	HP:0012497
HumanPheno	Soft skin	COL12A1 KCNH1 MAP3K7 TNXB	3.89e-04	44	41	4	HP:0000977
HumanPheno	Mitral valve prolapse	FLNA VWF PTPN11 MMP14 MAP3K7 TNXB	3.95e-04	123	41	6	HP:0001634
Domain	COLD_SHOCK	YBX1 YBX3 YBX2	3.03e-06	6	101	3	PS00352
Domain	Cold-shock_CS	YBX1 YBX3 YBX2	3.03e-06	6	101	3	IPR019844
Domain	CSP	YBX1 YBX3 YBX2	8.43e-06	8	101	3	SM00357
Domain	Cold_shock_prot	YBX1 YBX3 YBX2	8.43e-06	8	101	3	IPR011129
Domain	CSD	YBX1 YBX3 YBX2	8.43e-06	8	101	3	PF00313
Domain	CSP_DNA-bd	YBX1 YBX3 YBX2	8.43e-06	8	101	3	IPR002059
Domain	CTP_synthase_N	CTPS2 CTPS1	2.90e-05	2	101	2	IPR017456
Domain	K_chnl_volt-dep_EAG	KCNH1 KCNH5	2.90e-05	2	101	2	IPR003949
Domain	GATase1_CTP_Synthase	CTPS2 CTPS1	2.90e-05	2	101	2	IPR033828
Domain	CTP_synthase	CTPS2 CTPS1	2.90e-05	2	101	2	IPR004468
Domain	CTP_synth_N	CTPS2 CTPS1	2.90e-05	2	101	2	PF06418
Domain	GART_AS	GART ALDH1L1	8.66e-05	3	101	2	IPR001555
Domain	GART	GART ALDH1L1	8.66e-05	3	101	2	PS00373
Domain	-	GART ALDH1L1	1.73e-04	4	101	2	3.40.50.170
Domain	Formyl_transf_N	GART ALDH1L1	1.73e-04	4	101	2	IPR002376
Domain	Formyl_trans_N	GART ALDH1L1	1.73e-04	4	101	2	PF00551
Domain	VWA	COL6A3 COL12A1 VWF ITGAL	2.38e-04	56	101	4	PF00092
Domain	ACTININ_2	FLNA FLNB SYNE1	2.51e-04	23	101	3	PS00020
Domain	ACTININ_1	FLNA FLNB SYNE1	2.51e-04	23	101	3	PS00019
Domain	Actinin_actin-bd_CS	FLNA FLNB SYNE1	2.51e-04	23	101	3	IPR001589
Domain	GATase	CTPS2 CTPS1	2.86e-04	5	101	2	PF00117
Domain	GATASE_TYPE_1	CTPS2 CTPS1	4.28e-04	6	101	2	PS51273
Domain	GATASE	CTPS2 CTPS1	4.28e-04	6	101	2	IPR017926
Domain	-	FLNA FLNB SYNE1 CEP95	5.93e-04	71	101	4	1.10.418.10
Domain	CH-domain	FLNA FLNB SYNE1 CEP95	7.29e-04	75	101	4	IPR001715
Domain	Helicase/UvrB_N	FANCM SBNO1	7.94e-04	8	101	2	IPR006935
Domain	ResIII	FANCM SBNO1	7.94e-04	8	101	2	PF04851
Domain	VWFA	COL6A3 COL12A1 VWF ITGAL	1.02e-03	82	101	4	PS50234
Domain	VWA	COL6A3 COL12A1 VWF ITGAL	1.12e-03	84	101	4	SM00327
Domain	IG_FLMN	FLNA FLNB	1.27e-03	10	101	2	SM00557
Domain	-	CTPS2 CTPS1	1.27e-03	10	101	2	3.40.50.880
Domain	6PGD_dom_2	HIBADH EHHADH	1.27e-03	10	101	2	IPR013328
Domain	PAS_9	KCNH1 KCNH5	1.27e-03	10	101	2	PF13426
Domain	-	HIBADH EHHADH	1.27e-03	10	101	2	1.10.1040.10
Domain	Filamin	FLNA FLNB	1.54e-03	11	101	2	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB	1.54e-03	11	101	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB	1.54e-03	11	101	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB	1.54e-03	11	101	2	IPR017868
Domain	Class_I_gatase-like	CTPS2 CTPS1	1.84e-03	12	101	2	IPR029062
Domain	VWF_A	COL6A3 COL12A1 VWF ITGAL	2.05e-03	99	101	4	IPR002035
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH1 KCNH5	2.53e-03	14	101	2	IPR003938
Domain	ATPase_P-typ_TM_dom	ATP1A4 ATP2B3	3.31e-03	16	101	2	IPR023298
Domain	AT_hook	PRR12 KMT2C	3.31e-03	16	101	2	PF02178
Domain	-	ATP1A4 ATP2B3	3.31e-03	16	101	2	1.20.1110.10
Domain	FN3	COL6A3 COL12A1 RIMBP2 OSMR TNXB	3.32e-03	185	101	5	SM00060
Domain	ATPase_P-typ_cation-transptr_C	ATP1A4 ATP2B3	3.73e-03	17	101	2	IPR006068
Domain	Cation_ATPase_C	ATP1A4 ATP2B3	3.73e-03	17	101	2	PF00689
Domain	Cation_ATPase_N	ATP1A4 ATP2B3	4.19e-03	18	101	2	PF00690
Domain	Cation_ATPase_N	ATP1A4 ATP2B3	4.19e-03	18	101	2	SM00831
Domain	FN3	COL6A3 COL12A1 RIMBP2 OSMR TNXB	4.53e-03	199	101	5	PS50853
Domain	Fibrinogen_CS	FGA TNXB	4.66e-03	19	101	2	IPR020837
Domain	6-PGluconate_DH_C-like	HIBADH EHHADH	4.66e-03	19	101	2	IPR008927
Domain	ATPase_P-typ_cation-transptr_N	ATP1A4 ATP2B3	4.66e-03	19	101	2	IPR004014
Domain	CH	FLNA FLNB SYNE1	5.26e-03	65	101	3	SM00033
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL6A3 COL12A1 VWF ITGAL ACAN VCAN FGA MMP14 TNXB	2.23e-05	258	84	9	MM14572
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL6A3 COL12A1 VWF ITGAL ACAN VCAN FGA MMP14 TNXB	7.22e-05	300	84	9	M610
Pubmed	The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins.	FLNA YBX1 YBX3 YBX2	9.04e-09	9	103	4	8871564
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	FLNA FLNB COPA YBX1 GART ABCB1 PKMYT1 URB1 PTPN11 USO1 MAP3K7 VCL	2.24e-08	484	103	12	31995728
Pubmed	Cold shock domain family members YB-1 and MSY4 share essential functions during murine embryogenesis.	YBX1 YBX3 YBX2	2.52e-08	3	103	3	16954378
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	FLNA FLNB EPPK1 COPA YBX1 GART YBX3 MCCC2 DECR1 PTPN11 CTPS2 PELP1 SBNO1 USO1 ARHGEF1 DDX54 ZNF638 CTPS1 HECTD1	3.20e-08	1415	103	19	28515276
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	KIF13B FLNA COL6A3 COPA GART USO1 CTPS1 VCL	6.60e-08	179	103	8	36261009
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NES FLNA FLNB ZSWIM8 EPPK1 COPA GART URB1 PELP1 DDX54 ZNF638 HECTD1 VCL	7.30e-08	653	103	13	22586326
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNA FLNB COPA YBX1 SYNE1 GART YBX3 MCCC2 URB1 PTPN11 PELP1 SBNO1 USO1 DDX54 MPHOSPH8 CTPS1 ATP2B3 VCL	1.92e-07	1425	103	18	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	NES FLNA FLNB VWF COPA MAP2 PPFIA4 SYNE1 SYNPO ALDH1L1 MAPK8IP3 USO1 ARHGEF1 VCAN FGA RIMBP2 ATP2B3 VCL	2.04e-07	1431	103	18	37142655
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KIF13B FLNA FLNB COPA YBX1 PPFIA4 SYNE1 SYNPO YBX3 AKAP8L ABCB1 ABCB4 CYB5B YBX2 SBNO1 MPHOSPH8 ATP1A4 ATP2B3	2.28e-07	1442	103	18	35575683
Pubmed	Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.	COL6A3 COL12A1 FGA ATP2B3 VCL	3.94e-07	50	103	5	24769233
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NES FLNA FLNB COPA YBX1 GART YBX3 MCCC2 AKAP8L DECR1 URB1 ARHGEF1 DDX54 ZNF638 CTPS1 MMP14 VCL	4.71e-07	1353	103	17	29467282
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	FLNA FLNB EPPK1 COPA YBX1 CDH23 ASAP2 VCAN	5.28e-07	235	103	8	30258100
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	FLNA FLNB EPPK1 YBX1 YBX3 DECR1 PELP1 DDX54	7.23e-07	245	103	8	21182205
Pubmed	Brefeldin A-inhibited guanine exchange factor 2 regulates filamin A phosphorylation and neuronal migration.	NES FLNA VCL	8.75e-07	7	103	3	22956851
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	FLNA FLNB YBX1 YBX3 PKMYT1 CCNYL1 MAP3K7 RAD23A	1.16e-06	261	103	8	33277362
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	GPRASP1 FLNA COL12A1 EPPK1 SETD6 SYNPO HIBADH PEX26 KMT2C CEP95 VCAN ZNF638 OSMR TNXB HYDIN RAD23A	1.30e-06	1293	103	16	15342556
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	NES FLNA FLNB VWF GART AKAP8L USO1 ARHGEF1 ZNF638	1.32e-06	360	103	9	33111431
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	NES FLNA FLNB	1.40e-06	8	103	3	17145501
Pubmed	A human MAP kinase interactome.	FLNA VWF SYNE1 SYNPO CCDC88B KMT2C ASAP2 CEP95 ARHGEF1 MAP3K7	1.92e-06	486	103	10	20936779
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB VCL	2.09e-06	9	103	3	11807098
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNB COL6A3 COL12A1 VWF SETD6 SYNE1 PTPN11 NFE2L1 MAP3K7 VCL	2.34e-06	497	103	10	23414517
Pubmed	Expression of TGF-betas in the embryonic nervous system: analysis of interbalance between isoforms.	NES MAP2 VCAN	2.98e-06	10	103	3	18498095
Pubmed	Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.	FLNA FLNB ACAN	2.98e-06	10	103	3	24436304
Pubmed	Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.	NES KCNH1 KCNH5	2.98e-06	10	103	3	22855790
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	COL6A3 SYNPO YBX3 AKAP8L PRR12 YBX2 ACAN OSMR MAP3K7 HECTD1	3.09e-06	513	103	10	25798074
Pubmed	A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.	FLNA FLNB EPPK1 PTPN11	3.14e-06	34	103	4	12577067
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL6A3 COL12A1 VWF VCAN FGA TNXB	3.21e-06	135	103	6	28675934
Pubmed	ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.	NES MAP2 ACAN	4.09e-06	11	103	3	27909010
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNA EPPK1 KDM6B MAPK8IP3 PKMYT1 TBC1D16 ESRP2 PRR12 TLNRD1 KMT2C URB1 IFRD2 MMP14 HECTD1	4.88e-06	1105	103	14	35748872
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL6A3 COL12A1 VWF ACAN VCAN TNXB	5.05e-06	146	103	6	27068509
Pubmed	Defining the molecular character of the developing and adult kidney podocyte.	NES SYNPO NPHS2 FOXD1	5.51e-06	39	103	4	21931791
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	FLNA FLNB DCPS COPA MAP2 YBX1 GART YBX3 PTPN11 CTPS2 SBNO1 ARHGEF1 CTPS1 HECTD1 VCL RAD23A	5.87e-06	1455	103	16	22863883
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL6A3 COL12A1 VWF VCAN FGA TNXB	6.61e-06	153	103	6	25037231
Pubmed	Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.	VWF SYNPO NPHS2	7.06e-06	13	103	3	29114040
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	NES FLNA FLNB COPA YBX1 MCCC2 AKAP8L URB1 PELP1 DDX54 ZNF638 MPHOSPH8 VCL	7.41e-06	989	103	13	36424410
Pubmed	Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.	NES FLNA FLNB MAP2	8.19e-06	43	103	4	27664421
Pubmed	Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.	FLNA SYNPO ALDH1L1 MBLAC1 PTPN11 USO1 FGA CRYZL1	8.33e-06	341	103	8	29791485
Pubmed	Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.	ABCB1 ABCB4	8.69e-06	2	103	2	10488067
Pubmed	Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.	ABCB1 ABCB4	8.69e-06	2	103	2	21705081
Pubmed	Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.	ABCB1 ATP1A4	8.69e-06	2	103	2	10562306
Pubmed	The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.	ABCB1 ABCB4	8.69e-06	2	103	2	10552998
Pubmed	Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.	ABCB1 ABCB4	8.69e-06	2	103	2	28441502
Pubmed	Genetic dissection of the function of mammalian P-glycoproteins.	ABCB1 ABCB4	8.69e-06	2	103	2	9196326
Pubmed	Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.	ABCB1 ABCB4	8.69e-06	2	103	2	22184139
Pubmed	Isolation and expression of a complementary DNA that confers multidrug resistance.	ABCB1 ABCB4	8.69e-06	2	103	2	3022150
Pubmed	Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.	ABCB1 ABCB4	8.69e-06	2	103	2	2570420
Pubmed	MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.	ABCB1 ABCB4	8.69e-06	2	103	2	8898203
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	8.69e-06	2	103	2	17635842
Pubmed	YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis.	YBX1 MMP14	8.69e-06	2	103	2	20599698
Pubmed	Identification and characterization of versican/PG-M aggregates in cartilage.	ACAN VCAN	8.69e-06	2	103	2	16648631
Pubmed	Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus.	KDM6B ITGAL	8.69e-06	2	103	2	28430662
Pubmed	Functional distinction of human EAG1 and EAG2 potassium channels.	KCNH1 KCNH5	8.69e-06	2	103	2	11943152
Pubmed	Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.	ABCB1 ABCB4	8.69e-06	2	103	2	2473069
Pubmed	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	ABCB1 ABCB4	8.69e-06	2	103	2	28274756
Pubmed	A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.	ABCB1 ABCB4	8.69e-06	2	103	2	19185004
Pubmed	Cleavage of the carboxyl tail from the G3 domain of aggrecan but not versican and identification of the amino acids involved in the degradation.	ACAN VCAN	8.69e-06	2	103	2	11932252
Pubmed	Differential expression of the multidrug resistance 1 (MDR1) protein in prostate cancer cells is independent from anticancer drug treatment and Y box binding protein 1 (YB-1) activity.	YBX1 ABCB1	8.69e-06	2	103	2	25544376
Pubmed	Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.	ABCB1 ABCB4	8.69e-06	2	103	2	18215618
Pubmed	Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen.	VWF FGA	8.69e-06	2	103	2	10930441
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	8.69e-06	2	103	2	21325628
Pubmed	YB-3 substitutes YB-1 in global mRNA binding.	YBX1 YBX3	8.69e-06	2	103	2	31944153
Pubmed	Regulation of MDR1 gene expression in multidrug-resistant cancer cells is independent from YB-1.	YBX1 ABCB1	8.69e-06	2	103	2	17418094
Pubmed	[Microtubule-associated protein 2 and nestin expressions in human embryonic and fetal gastric tissues].	NES MAP2	8.69e-06	2	103	2	22985576
Pubmed	What have we learnt thus far from mice with disrupted P-glycoprotein genes?	ABCB1 ABCB4	8.69e-06	2	103	2	8763339
Pubmed	[Effect of regulation of Y-box protein 1 by RNA interference on the doxorubicin induced mdr1 gene expression in K562 cells].	YBX1 ABCB1	8.69e-06	2	103	2	21781495
Pubmed	Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.	ABCB1 ABCB4	8.69e-06	2	103	2	9473291
Pubmed	The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.	ABCB1 ABCB4	8.69e-06	2	103	2	2471060
Pubmed	Differential distribution of Y-box-binding protein 1 and cold shock domain protein A in developing and adult human brain.	YBX1 YBX3	8.69e-06	2	103	2	24817634
Pubmed	MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.	ABCB1 ABCB4	8.69e-06	2	103	2	18231753
Pubmed	MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.	YBX3 YBX2	8.69e-06	2	103	2	11564883
Pubmed	ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.	ABCB1 ABCB4	8.69e-06	2	103	2	32058310
Pubmed	Vinculin negatively regulates transcription of MT1-MMP through MEK/ERK pathway.	MMP14 VCL	8.69e-06	2	103	2	25449281
Pubmed	Prolactin increases expression of cytoskeletal proteins in SK-N-SH cells.	NES MAP2	8.69e-06	2	103	2	25629269
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	8.69e-06	2	103	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	8.69e-06	2	103	2	33649519
Pubmed	A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4.	YBX3 YBX2	8.69e-06	2	103	2	10772793
Pubmed	Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.	ABCB1 ABCB4	8.69e-06	2	103	2	3768958
Pubmed	Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression.	YBX3 YBX2	8.69e-06	2	103	2	26646932
Pubmed	Evidence that differential packaging of the major platelet granule proteins von Willebrand factor and fibrinogen can support their differential release.	VWF FGA	8.69e-06	2	103	2	17650077
Pubmed	Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.	ABCB1 ABCB4	8.69e-06	2	103	2	38522903
Pubmed	Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.	ABCB1 ABCB4	8.69e-06	2	103	2	3477522
Pubmed	Roles of surface residues of intracellular domains of heag potassium channels.	KCNH1 KCNH5	8.69e-06	2	103	2	19172261
Pubmed	Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.	ABCB1 ABCB4	8.69e-06	2	103	2	16857572
Pubmed	High glucose alters the expression of genes involved in proliferation and cell-fate specification of embryonic neural stem cells.	NES MAP2	8.69e-06	2	103	2	16508779
Pubmed	Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.	ABCB1 ABCB4	8.69e-06	2	103	2	1969609
Pubmed	The expression of P-glycoprotein in leukemia cells is associated with the upregulated expression of nestin, a class 6 filament protein.	NES ABCB1	8.69e-06	2	103	2	27479651
Pubmed	Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.	ABCB1 ABCB4	8.69e-06	2	103	2	24140176
Pubmed	Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.	ABCB1 ABCB4	8.69e-06	2	103	2	9419367
Pubmed	Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.	ABCB1 ABCB4	8.69e-06	2	103	2	2248681
Pubmed	[Effects of changwelqing on nuclear translocation of Y-box binding protein-1 and expression of P-glycoprotein in human colon cancer cell line with drug-resistance induced by vincristine].	YBX1 ABCB1	8.69e-06	2	103	2	20929136
Pubmed	Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2.	YBX1 YBX2	8.69e-06	2	103	2	9780336
Pubmed	The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.	ABCB1 ABCB4	8.69e-06	2	103	2	17440929
Pubmed	Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.	ABCB1 ABCB4	8.69e-06	2	103	2	7832992
Pubmed	Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.	ABCB1 ABCB4	8.69e-06	2	103	2	11826402
Pubmed	Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human breast carcinoma.	YBX1 ABCB1	8.69e-06	2	103	2	12565174
Pubmed	CTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1.	YBX1 CTPS1	8.69e-06	2	103	2	34991621
Pubmed	Bioinformatics analysis identified MMP14 and COL12A1 as immune-related biomarkers associated with pancreatic adenocarcinoma prognosis.	COL12A1 MMP14	8.69e-06	2	103	2	34517516
Pubmed	mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.	ABCB1 ABCB4	8.69e-06	2	103	2	10453001
Pubmed	Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.	CTPS2 CTPS1	8.69e-06	2	103	2	20739275
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NES FLNA FLNB EPPK1 COPA YBX1 SYNE1 GART ABCB1 URB1 PELP1 DDX54 ZNF638	1.07e-05	1024	103	13	24711643
Cytoband	5q12-q13	MCCC2 FOXD1	2.98e-05	4	103	2	5q12-q13
Cytoband	16q22.1	ESRP2 CYB5B CDH8 CA7	1.15e-04	110	103	4	16q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	ESRP2 CYB5B HYDIN CA7	7.94e-04	183	103	4	chr16q22
Cytoband	17p13.1	KDM6B YBX2 PLSCR3	2.43e-03	118	103	3	17p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr12q24	UNC119B PTPN11 SBNO1 DDX54 RIMBP2	2.50e-03	415	103	5	chr12q24
Cytoband	1q23.2	COPA ATP1A4	2.83e-03	35	103	2	1q23.2
GeneFamily	Y box binding proteins	YBX1 YBX3 YBX2	4.65e-08	3	66	3	106
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ACAN VCAN	7.84e-05	4	66	2	574
GeneFamily	ATP binding cassette subfamily B	ABCB1 ABCB4	7.07e-04	11	66	2	806
Coexpression	GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN	GTF2A1L YBX3 MCCC2 ALDH1L1 URB1 ASAP2 NFE2L1 RAD23A	9.78e-07	193	103	8	M3137
Coexpression	GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP	NES FLNB ESRP2 GUCA1A NFE2L1 ARHGEF1 VCAN RAD23A	1.28e-06	200	103	8	M9060
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP	COL6A3 COL12A1 VWF INPP5D ASAP2 VCAN	4.43e-05	162	103	6	M45037
Coexpression	SCHERER_PBMC_YF_VAX_AGE_18_40YO_4_TO_7DY_DN	MYO1G FLNA POLM PPFIA4 PSTPIP1 CCDC88B AKAP8L	5.29e-05	245	103	7	M41070
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	MYO1G FLNA YBX1 SYNE1 INPP5D PSTPIP1 ITGAL CCDC88B ABCB1 KMT2C PTPN11 SBNO1 ARHGEF1 ZNF638 MPHOSPH8 RNF139 NIN	6.87e-05	1492	103	17	M40023
Coexpression	MURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL	NES FLNA COL6A3 COL12A1 COPA YBX1 TBC1D16 VCAN OSMR VCL NIN	7.68e-05	681	103	11	M39175
Coexpression	NABA_CORE_MATRISOME	COL6A3 COL12A1 VWF ACAN VCAN FGA TNXB	9.72e-05	270	103	7	MM17057
Coexpression	NABA_CORE_MATRISOME	COL6A3 COL12A1 VWF ACAN VCAN FGA TNXB	1.09e-04	275	103	7	M5884
Coexpression	GSE27786_BCELL_VS_CD4_TCELL_DN	FLNA ITGAL CCDC88B NPHS2 ARHGEF1 HECTD1	1.34e-04	198	103	6	M4800
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN	ABCB4 USO1 VCAN CTPS1 VCL RAD23A	1.34e-04	198	103	6	M3792
Coexpression	GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN	YBX1 SETD6 DECR1 IFRD2 FGA CTPS1	1.38e-04	199	103	6	M3313
Coexpression	GSE20715_WT_VS_TLR4_KO_LUNG_DN	VWF SYNE1 INPP5D HIBADH MAPK8IP3 MMP14	1.38e-04	199	103	6	M4350
Coexpression	GSE7831_1H_VS_4H_CPG_STIM_PDC_DN	MXD3 FLNB ITGAL PKMYT1 SBNO1 FGA	1.38e-04	199	103	6	M6961
Coexpression	GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_UP	YBX1 KDM6B TBC1D16 PELP1 IFRD2 VCL	1.42e-04	200	103	6	M9493
Coexpression	GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN	FLNB COPA KCNH1 ZNF638 OSMR VCL	1.42e-04	200	103	6	M9677
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	FLNA COL6A3 COL12A1 COPA VCAN MMP14	1.42e-04	200	103	6	M5930
Coexpression	GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP	GPRASP1 COL6A3 DCPS PPFIA4 GUCA1A KCNH1	1.42e-04	200	103	6	M8209
Coexpression	GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN	SBNO1 NFE2L1 DDX54 FGA HECTD1 CDH8	1.42e-04	200	103	6	M9563
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN	FLNB YBX3 ABCB4 PTPN11 GUCA1A FOXD1	1.42e-04	200	103	6	M3752
Coexpression	GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP	GPRASP1 NES DCPS HIBADH DECR1 GUCA1A	1.42e-04	200	103	6	M4103
Coexpression	GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN	UNC119B VWF ARMCX4 ESRP2 PTPN11 MMP14	1.42e-04	200	103	6	M4354
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA COL6A3 COL12A1 YBX2 CCNYL1 ACAN VCAN	9.79e-08	161	103	7	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA COL6A3 COL12A1 YBX2 CCNYL1 ACAN VCAN	9.79e-08	161	103	7	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB VWF ARMCX4 ABCB4 NFE2L1 OSMR CA7	2.17e-07	181	103	7	4ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FLNA COL6A3 SYNE1 VCAN ATP1A4 TNXB VCL	4.26e-07	200	103	7	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC119B CDH23 CCNYL1 EHHADH DDX54 NIN	2.21e-06	163	103	6	7a04192710f55acf5a4681d5f09942358fdb02ff
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	COL6A3 COL12A1 GUCA1A ACAN VCAN MMP14	2.28e-06	164	103	6	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G FLNA COL6A3 SYNE1 INPP5D ITGAL	3.44e-06	176	103	6	6b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCell	10x5'-blood\|World / Manually curated celltypes from each tissue	MYO1G FLNA COL6A3 VCAN PLSCR3 VCL	5.83e-06	193	103	6	359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPRASP1 MAPK8IP3 RIMBP2 NYAP1 ATP2B3 CDH8	5.83e-06	193	103	6	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	COVID-19-lung-NK_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B ARHGEF1	6.01e-06	194	103	6	4c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCell	Control-CD8+_Tem\|Control / Disease condition and Cell class	MYO1G FLNA SYNE1 YBX3 ITGAL NIN	6.19e-06	195	103	6	7503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCell	normal_Lung-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	MYO1G FLNA SYNE1 YBX3 ITGAL NIN	6.19e-06	195	103	6	3af8ea15e2ac8efdeb4d4f69357b83b8dbcfab8d
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytotoxic_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYO1G FLNA SYNE1 PSTPIP1 ITGAL ARHGEF1	6.19e-06	195	103	6	730c613cf6f4d16ca51fd44de1f5a883f615c5c5
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B VCAN	6.75e-06	198	103	6	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA COL6A3 SYNE1 ATP1A4 TNXB VCL	6.95e-06	199	103	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B ABCB1	6.95e-06	199	103	6	713fab2e946b300d21215aff1553785e8857ce65
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A3 SYNE1 VCAN OSMR MMP14 TNXB	6.95e-06	199	103	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A3 SYNE1 VCAN OSMR MMP14 TNXB	6.95e-06	199	103	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A3 SYNE1 VCAN OSMR MMP14 TNXB	6.95e-06	199	103	6	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	tumor_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	FLNB COL6A3 COL12A1 VCAN MMP14 VCL	6.95e-06	199	103	6	f89d67e3d8cd48ef5c30a5ad71764f4ebbc8bcb3
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B ABCB1	6.95e-06	199	103	6	ffd5b4d58d81b76e01d87016209f16879d81c592
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A3 SYNE1 VCAN OSMR MMP14 TNXB	7.15e-06	200	103	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	GPRASP1 SBNO1 KCNH1 RIMBP2 MPHOSPH8 NYAP1	7.15e-06	200	103	6	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNB COL12A1 VWF KMT2C ASAP2 NIN	7.15e-06	200	103	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NES FLNA SYNE1 ACAN ATP1A4 VCL	7.15e-06	200	103	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNA COL6A3 SYNE1 ATP1A4 TNXB VCL	7.15e-06	200	103	6	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NES FLNA SYNE1 ACAN ATP1A4 VCL	7.15e-06	200	103	6	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	FLNA COL6A3 SYNE1 VCAN ATP1A4 VCL	7.15e-06	200	103	6	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA COL6A3 SYNE1 ATP1A4 TNXB VCL	7.15e-06	200	103	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	NES FLNA SYNE1 ACAN ATP1A4 VCL	7.15e-06	200	103	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	metastatic_Lymph_Node-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	COL6A3 COL12A1 VCAN MMP14	2.50e-05	73	103	4	116259a036373bccaeb77fe3c675741a5ca81c52
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	UNC119B ZSWIM8 GART CDH23 PKMYT1	2.94e-05	154	103	5	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MXD3 FLNB VWF CCNYL1 CTPS1	3.03e-05	155	103	5	8e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NES VWF ABCB1 ASAP2 NFE2L1	3.13e-05	156	103	5	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G PPFIA4 ITGAL CCDC88B CA7	3.23e-05	157	103	5	904cd98ae85ed6459e0663f077ac462842bf12df
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G INPP5D PSTPIP1 CCDC88B NPHS2	3.64e-05	161	103	5	16f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G INPP5D PSTPIP1 CCDC88B NPHS2	3.64e-05	161	103	5	f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1G FLNA SYNE1 ABCB1 FOXD1	3.64e-05	161	103	5	bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G INPP5D PSTPIP1 CCDC88B NPHS2	3.64e-05	161	103	5	58a32a1033f379579697bda1bbf047a088e4a34f
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF13B INPP5D CCDC88B GUCA1A HERC3	3.75e-05	162	103	5	388670cf3acef17df971c0d8ae3ce14398945192
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF13B INPP5D CCDC88B GUCA1A HERC3	3.75e-05	162	103	5	9333d923225df7bfdf6b3a4c32816751315aec50
ToppCell	tumor_Lung-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	MYO1G FLNA SYNE1 YBX3 ITGAL	3.97e-05	164	103	5	60fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO1G FLNB TLNRD1 VCAN MMP14	4.21e-05	166	103	5	ce570b768988e30898cf0387c2aa99989631f13f
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MXD3 CABLES2 COL6A3 COL12A1 VCAN	4.21e-05	166	103	5	49103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAP2 PKMYT1 KMT2C ENTPD6 RNF139	4.46e-05	168	103	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF SYNPO PEX26 YBX2 KCNH1	4.46e-05	168	103	5	32e4d82efaccf336d347e4063253c3635a3ec672
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NES VWF ABCB1 ABCB4 TNXB	4.58e-05	169	103	5	0d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF TLNRD1 KCNH1 OSMR CTPS1	4.71e-05	170	103	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF TLNRD1 KCNH1 OSMR CTPS1	4.71e-05	170	103	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G PSTPIP1 ITGAL CCDC88B ABCB1	4.71e-05	170	103	5	c4f00c1acde1d3b521101e469101d10fd257653e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G PSTPIP1 ITGAL CCDC88B ABCB1	4.71e-05	170	103	5	d3c1edaf0190d8927578043c372dba7477e75e14
ToppCell	Monocytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	MYO1G CDH23 PSTPIP1 ITGAL VCAN	4.71e-05	170	103	5	4e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCell	severe_influenza-B_cell\|World / disease group, cell group and cell class (v2)	YBX3 KDM6B ABCB1 ABCB4	4.76e-05	86	103	4	7b595bcba4bcb72b7de7c06e19f690f0c739c529
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 COL12A1 MAP2 ACAN VCAN	4.85e-05	171	103	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CABLES2 NES VWF ABCB1 OSMR	4.85e-05	171	103	5	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 COL12A1 MAP2 ACAN VCAN	4.85e-05	171	103	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G PSTPIP1 ITGAL CCDC88B ABCB1	5.12e-05	173	103	5	6397b3fa72e2621a9a0f27f49446de2d3a30e420
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4\|TCGA-Adrenal / Sample_Type by Project: Shred V9	ABCB4 PKMYT1 CYB5B SIX5 TNXB	5.26e-05	174	103	5	15e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	MXD3 FANCM ACAN SIX5 MMP14	5.26e-05	174	103	5	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 COL12A1 VCAN PLSCR3 FOXD1	5.56e-05	176	103	5	fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL6A3 NPHS2 SIX5 TNXB FOXD1	5.86e-05	178	103	5	cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B	6.18e-05	180	103	5	bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1G INPP5D PSTPIP1 ITGAL CCDC88B	6.18e-05	180	103	5	c62417f205bcbf3b212ae177f63562ec6467c855
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	FLNA SYNE1 ITGAL ABCB1 VCL	6.68e-05	183	103	5	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL6A3 NPHS2 HYDIN FOXD1	6.68e-05	183	103	5	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FLNB COL12A1 MAP2 SYNPO RIMBP2	6.68e-05	183	103	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL6A3 COL12A1 GUCA1A ACAN MMP14	6.86e-05	184	103	5	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	facs-Lung-24m-Hematologic-myeloid\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1G FLNA PPFIA4 ITGAL CCDC88B	6.86e-05	184	103	5	c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 SYNPO NPHS2 HYDIN FOXD1	6.86e-05	184	103	5	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL12A1 VWF ABCB1 TLNRD1 ASAP2	7.04e-05	185	103	5	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF SYNPO CCNYL1 OSMR CA7	7.04e-05	185	103	5	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G INPP5D PSTPIP1 ITGAL ABCB1	7.22e-05	186	103	5	885aed2472cead81d60c9f3a28c0ff10eb449592
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES FLNB VWF YBX1 KDM6B	7.22e-05	186	103	5	f8ed078684ce6d914fd9cb1f0ef4aba36db39b3f
ToppCell	facs-Heart-LA-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES FLNB VWF YBX1 KDM6B	7.22e-05	186	103	5	1d08e60d239153c9e5ea42135d702d494d8b42b1
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF ARMCX4 CCNYL1 OSMR	7.22e-05	186	103	5	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF SYNPO ARMCX4 OSMR CTPS1	7.22e-05	186	103	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB VWF YBX3 ABCB1 NFE2L1	7.22e-05	186	103	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF SYNPO OSMR CTPS1	7.22e-05	186	103	5	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF SYNPO OSMR CTPS1	7.22e-05	186	103	5	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF ARMCX4 CCNYL1 OSMR	7.40e-05	187	103	5	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF ARMCX4 CCNYL1 OSMR	7.40e-05	187	103	5	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF SYNPO CCNYL1 OSMR CA7	7.40e-05	187	103	5	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	Pericytes-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	NES COL6A3 COL12A1 ACAN CDH8	7.59e-05	188	103	5	f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB VWF ARMCX4 ASAP2 MPHOSPH8	7.59e-05	188	103	5	59f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCell	wk_08-11-Epithelial-PNS-MFNG+_DBH+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KIF13B DBH ABCB1 ATP2B3 KCNH5	7.59e-05	188	103	5	d3d7d21d4fa39ac4106a164652673de1bef8662d
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	MYO1G INPP5D CDH23 ITGAL VCAN	7.78e-05	189	103	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	MYO1G FLNA ITGAL CCDC88B MMP14	7.78e-05	189	103	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G SYNE1 INPP5D ITGAL ARHGEF1	7.98e-05	190	103	5	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF SYNPO OSMR CTPS1	7.98e-05	190	103	5	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1G INPP5D PSTPIP1 ITGAL ARHGEF1	7.98e-05	190	103	5	b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCell	droplet-Marrow-nan-21m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G FLNB PPFIA4 PKMYT1 CTPS2	7.98e-05	190	103	5	6c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB VWF YBX3 ASAP2 KCNH1	8.18e-05	191	103	5	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1G INPP5D PSTPIP1 ITGAL ARHGEF1	8.18e-05	191	103	5	1a2d5fec2bea96da2154b0aed252f1bb35102f6e
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB VWF SYNPO ARMCX4 KCNH1	8.18e-05	191	103	5	27f23c2254b610abac1a88d0fecff305addde9da
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1G INPP5D PSTPIP1 ITGAL ARHGEF1	8.18e-05	191	103	5	326b4541069efedc8ab409f85bb11f77346dda90
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	FLNB VWF MAP2 SYNE1 CDH23	8.18e-05	191	103	5	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB VWF ASAP2 KCNH1 SIX5	8.38e-05	192	103	5	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	droplet-Lung-nan-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB VWF ARMCX4 ASAP2 KCNH1	8.38e-05	192	103	5	45929c757d873fe314cc36d27abd265414635490
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B COL12A1 VCAN MMP14 TNXB	8.38e-05	192	103	5	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB VWF INPP5D ABCB1 TLNRD1	8.38e-05	192	103	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
Drug	hydroxyl radicals	COL6A3 VWF COPA GART DBH MCCC2 ALDH1L1 HIBADH ABCB1 ABCB4 DECR1 PTPN11 CTPS2 EHHADH ENTPD6 FGA CTPS1 MMP14 ATP2B3 CA7	1.77e-06	1341	102	20	CID000000961
Drug	Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; PC3; HT_HG-U133A	ITGAL ABCB1 URB1 NPHS2 ACAN HERC3 MMP14 VCL	2.98e-06	197	102	8	5768_UP
Drug	colchine	COL6A3 COL12A1 MAP2 DBH ABCB1 ABCB4 ACAN VCAN VCL KCNH5	8.70e-06	383	102	10	CID000002833
Drug	AC1L9E0Q	ABCB1 ABCB4 KCNH1 KCNH5	9.51e-06	30	102	4	CID000443095
Drug	Gdrgdsp	VWF ACAN FGA MMP14 TNXB VCL	9.72e-06	109	102	6	CID000115346
Drug	Ro 44-9883	VWF FGA MMP14 VCL	1.09e-05	31	102	4	CID000071453
Drug	trimetrexate	SYNE1 GART ABCB1 DECR1	1.41e-05	33	102	4	CID000005582
Drug	1,9-dideoxyforskolin	ABCB1 ABCB4	1.99e-05	2	102	2	ctd:C047983
Drug	BrEpG	DBH DECR1	1.99e-05	2	102	2	CID000158717
Drug	1-benzosuberone	SYNE1 NPHS2	1.99e-05	2	102	2	CID000070003
Drug	Methotrexate [59-05-2]; Up 200; 8.8uM; HL60; HG-U133A	UNC119B FLNA POLM SETD6 KDM6B CYB5B PLSCR3	2.47e-05	191	102	7	2041_UP
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A	ZSWIM8 PEX26 MAPK8IP3 URB1 GUCA1A ACAN MMP14	2.73e-05	194	102	7	3716_UP
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Down 200; 11.8uM; PC3; HT_HG-U133A	MXD3 POLM ITGAL ARHGEF1 DDX54 PLSCR3 ATP2B3	2.82e-05	195	102	7	4015_DN
Drug	Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A	EPPK1 SYNE1 MAPK8IP3 URB1 NPHS2 MMP14 ATP2B3	3.32e-05	200	102	7	4176_UP
Disease	Frontometaphyseal dysplasia	FLNA MAP3K7	1.09e-05	2	98	2	C0265293
Disease	FRONTOMETAPHYSEAL DYSPLASIA 1	FLNA MAP3K7	1.09e-05	2	98	2	C4281559
Disease	Frontometaphyseal dysplasia	FLNA MAP3K7	1.09e-05	2	98	2	cv:C0265293
Disease	brain ischemia (biomarker_via_orthology)	NES MAP2 DBH ABCB1 MMP14	2.35e-05	102	98	5	DOID:2316 (biomarker_via_orthology)
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB	3.27e-05	3	98	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB	3.27e-05	3	98	2	DOID:0111190 (implicated_via_orthology)
Disease	Ullrich congenital muscular dystrophy	COL6A3 COL12A1	6.52e-05	4	98	2	cv:C4551860
Disease	Bethlem myopathy	COL6A3 COL12A1	6.52e-05	4	98	2	cv:C1834674
Disease	BETHLEM MYOPATHY 1	COL6A3 COL12A1	6.52e-05	4	98	2	C1834674
Disease	Ullrich congenital muscular dystrophy 1	COL6A3 COL12A1	6.52e-05	4	98	2	C0410179
Disease	Bethlem myopathy (is_implicated_in)	COL6A3 COL12A1	6.52e-05	4	98	2	DOID:0050663 (is_implicated_in)
Disease	Ullrich congenital muscular dystrophy (is_implicated_in)	COL6A3 COL12A1	6.52e-05	4	98	2	DOID:0050558 (is_implicated_in)
Disease	Disproportionate short stature	FLNA FLNB PTPN11 ACAN	1.29e-04	77	98	4	C0878659
Disease	neutrophil count	MYO1G NES FLNB DCPS COPA INPP5D CDH23 PSTPIP1 KDM6B ITGAL SBNO1 ATP1A4 TNXB HYDIN	1.88e-04	1382	98	14	EFO_0004833
Disease	myocardial infarction (biomarker_via_orthology)	VWF YBX1 VCAN MMP14 MAP3K7	1.99e-04	160	98	5	DOID:5844 (biomarker_via_orthology)
Disease	systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus	FLNB PRR12 PTPN11	2.75e-04	38	98	3	EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Disease	gallbladder neoplasm	ABCB1 ABCB4	3.87e-04	9	98	2	EFO_0004606
Disease	cystic fibrosis (implicated_via_orthology)	ABCB1 ABCB4	3.87e-04	9	98	2	DOID:1485 (implicated_via_orthology)
Disease	amino acid measurement	VWF GTF2A1L SYNE1 SYNPO HIBADH PKMYT1 PELP1 VCAN MAP3K7	4.33e-04	678	98	9	EFO_0005134
Disease	age at menarche, spine bone mineral density	ABCB1 KCNH1	4.83e-04	10	98	2	EFO_0004703, EFO_0007701
Disease	Immature Reticulocyte Fraction Measurement	IFRD2 OSMR	4.83e-04	10	98	2	EFO_0009253
Disease	Epilepsy	FLNA ABCB1 KCNH1 KCNH5	4.87e-04	109	98	4	C0014544
Disease	Neuroblastoma	DBH ABCB1 PTPN11	5.18e-04	47	98	3	C0027819
Disease	cholestasis (biomarker_via_orthology)	ALDH1L1 ABCB1 ABCB4	5.86e-04	49	98	3	DOID:13580 (biomarker_via_orthology)
Disease	rheumatoid arthritis (implicated_via_orthology)	KMT2C MMP14	7.05e-04	12	98	2	DOID:7148 (implicated_via_orthology)
Disease	renal cell carcinoma (is_marker_for)	VWF KDM6B ABCB1 KCNH1	8.91e-04	128	98	4	DOID:4450 (is_marker_for)
Disease	Pneumoconiosis	CDH23 ACAN	9.68e-04	14	98	2	C0032273
Disease	Bagassosis	CDH23 ACAN	9.68e-04	14	98	2	C0004681
Disease	response to methotrexate, aspartate aminotransferase measurement	MAP2 RIMBP2	9.68e-04	14	98	2	EFO_0004736, GO_0031427
Disease	unipolar depression, mood disorder, response to antidepressant	NFE2L1 CDH8	9.68e-04	14	98	2	EFO_0003761, EFO_0004247, GO_0036276
Disease	intracranial aneurysm (is_marker_for)	VWF MMP14	9.68e-04	14	98	2	DOID:10941 (is_marker_for)
Disease	Liver Cirrhosis, Experimental	FLNA COL12A1 VWF YBX1 INPP5D ALDH1L1 PSTPIP1 ITGAL ABCB1	1.11e-03	774	98	9	C0023893
Disease	Nephrosis	NES NPHS2	1.11e-03	15	98	2	C0027720
Disease	Schizoaffective disorder-bipolar type	MYO1G PKMYT1	1.27e-03	16	98	2	EFO_0009965
Disease	Intrahepatic cholestasis of pregnancy	ABCB1 ABCB4	1.27e-03	16	98	2	EFO_0009048
Disease	muscular dystrophy (is_implicated_in)	COL6A3 SYNE1	1.44e-03	17	98	2	DOID:9884 (is_implicated_in)
Disease	C-X-C motif chemokine 16 measurement	CDH23 PELP1	1.61e-03	18	98	2	EFO_0010911
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	1.80e-03	19	98	2	DOID:2256 (is_implicated_in)
Disease	asthma, response to diisocyanate	COL12A1 ASAP2 VCAN ENTPD6 NIN	1.81e-03	261	98	5	EFO_0006995, MONDO_0004979
Disease	epilepsy (implicated_via_orthology)	ABCB1 KCNH1 ATP1A4 KCNH5	2.17e-03	163	98	4	DOID:1826 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	FLNA ABCB1 KCNH1	2.60e-03	82	98	3	C0086237
Disease	Awakening Epilepsy	FLNA ABCB1 KCNH1	2.60e-03	82	98	3	C0751111
Disease	Aura	FLNA ABCB1 KCNH1	2.60e-03	82	98	3	C0236018
Disease	descending aortic diameter	FLNB COL6A3 TBC1D16	3.18e-03	88	98	3	EFO_0021788

Protein segments in the cluster

Peptide	Gene	Start	Entry
EIGDVLLARFDGAEG	ARHGEF1	491	Q92888
ALGLAGLVGEAEDSE	CCDC88B	21	A6NC98
IDEGLGEVGTVNEID	VCAN	2041	P13611
EVLSGFISREEGEVG	ALPK3	1566	Q96L96
ASGDGDGEDAVVILE	DCPS	71	Q96C86
GAEGKFEIDESTGLI	CDH23	1251	Q9H251
AVVEPAELDFGEGEG	CCNYL1	46	Q8N7R7
VESRLGAGEEAGVES	ARMCX4	1861	Q5H9R4
GIIFTLLGAGGEEEE	ATP2B3	286	Q16720
EATEGLEGTEAVEKG	AKAP8L	311	Q9ULX6
EILAEAAGFEGSEGR	POLM	161	Q9NP87
ETEVIIIEVDEEGGG	MMP14	521	P50281
IIEVDEEGGGAVSAA	MMP14	526	P50281
EQGFGEDLEDLGAVA	NFE2L1	146	Q14494
LADISDVEGEVGAIG	RAD23A	291	P54725
VEEERIAGTEGGFSL	OSMR	531	Q99650
EETGGLGVDIVLDAG	CRYZL1	211	O95825
SGLAEETDIDVVGEG	FOXD1	11	Q16676
DVIAGFDDGVIVEKG	ABCB1	596	P08183
SAGDILEVILEGEDG	PSTPIP1	381	O43586
AVDDETKGVEGTDGV	KMT2C	1256	Q8NEZ4
LEVDVESLVFGGEAE	MXD3	171	Q9BW11
SEVIGDVDEGADLLG	MAPK8IP3	391	Q9UPT6
TGEEVSAEDLGGADL	MCCC2	251	Q9HCC0
LKVIFDGEEAVDAGG	HERC3	731	Q15034
DGEEAVDAGGVTKEF	HERC3	736	Q15034
GVRDGAAEEEGTVEL	PPFIA4	201	O75335
DELTFSEGDVIIVDG	ASAP2	961	O43150
VSTCVGEEGLDIGEV	FANCM	541	Q8IYD8
EDGEILEELFFGTEG	KDM6B	496	O15054
DEVVAILGKGDVFGD	KCNH5	601	Q8NCM2
AGESVEDIFSEVVGR	DDX54	641	Q8TDD1
ELGGVDLVIEAVFEE	EHHADH	371	Q08426
TAGAGVGDIGVEVED	FLNB	381	O75369
GGLVREALTDADDFG	PLSCR3	241	Q9NRY6
EAEELVVGSAAFGEE	PEX26	176	Q7Z412
IEVEEVVGRGAFGVV	MAP3K7	36	O43318
RGSGEEGTEVVALLE	NPHS2	71	Q9NP85
DGFTGKEEVVEQGEL	NES	986	P48681
DDEVVAILGKGDVFG	KCNH1	631	O95259
ADTEAGEELSGDGLV	FAM161B	26	Q96MY7
VGGGERFDSLTDLVE	PTPN11	181	Q06124
ELEEVEDLEFGTAGG	PELP1	956	Q8IZL8
GEEVLEISASGFGDL	ACAN	1531	P16112
NADVIAGFEDGVIVE	ABCB4	596	P21439
EASVGDGFTGDIAID	MALRD1	1001	Q5VYJ5
VIKFDGGEEVLISGE	DECR1	296	Q16698
KSVLEVEFLGEEGTG	HECTD1	2156	Q9ULT8
AEGGLDFGIVRVTEE	HYDIN	3051	Q4G0P3
AGDALFGEGTTLEER	COL12A1	891	Q99715
DFVVEAIGDDVGTLG	FLNA	596	P21333
DGFVEATEGLGDDAL	COPA	856	P53621
GEKDVVFLLDGSEGV	COL6A3	1026	P12111
GGEEVLLEQAGVDAS	CYB5B	61	O43169
EDRELATVGGFGILE	DBH	471	P09172
DGDEAESTGEIIRLG	CEP95	171	Q96GE4
TAGDALIEGSVEEGA	FGA	761	P02671
NGDGELSLEEFIEGV	GUCA1A	146	P43080
TVVVAGDVFERDGDE	MBLAC1	186	A4D2B0
GGECEEEIVRFGFEV	IFRD2	406	Q12894
DGLAVVGVFLETGDE	CA7	141	P43166
GGGEEDTEAFDIATL	CDH8	671	P55286
EALEEGGGELNDFVS	SBNO1	641	A3KN83
FELEGVELGADGKVV	CABLES2	226	Q9BTV7
TEELAEVEEGVGVVG	MPHOSPH8	21	Q99549
EVEEGVGVVGEDNDA	MPHOSPH8	26	Q99549
EEEEEEVGAATFGAG	NYAP1	616	Q6ZVC0
GLGILAFIGSTEEDD	RNF139	306	Q8WU17
SGEQVDIEAGIGEEA	GPRASP1	556	Q5JY77
SGDVGERIAGGDEVA	KIF13B	841	Q9NQT8
ERIAGGDEVAEVSFE	KIF13B	846	Q9NQT8
IISEEGNSDGGIVVE	USO1	216	O60763
CTGDIITVFGEIDED	RIMBP2	981	O15034
VEGLAEGTEDLDGEL	SYNE1	5821	Q8NF91
DAEKGGSLVVGDFEI	ENTPD6	396	O75354
CQVIGEEEVEGDGAL	NIN	1036	Q8N4C6
GEVGVEEEPFALGAE	SYNPO	656	Q8N3V7
LSVEEAVAAGVVGGE	EPPK1	2281	P58107
LSVEEAVAAGVVGGE	EPPK1	4416	P58107
GEVFVLDDGGEVDLD	CTPS1	56	P17812
GENEEGSEGELVVKF	INPP5D	766	Q92835
LGATAGGEVDEGLEA	SIX5	706	Q8N196
EGAFVIGREEVLTEE	SETD6	351	Q8TBK2
GLGLETDATEDDFGV	ESRP2	186	Q9H6T0
LEGDGLADVAVGAES	ITGAL	591	P20701
AIEGGAEDLGQEEVV	PRR12	1991	Q9ULL5
VLVEGSEGLDEEIGF	URB1	756	O60287
GGVEDEFAAAQELLG	HIBADH	176	P31937
IGGEFVDAEGAKTSE	ALDH1L1	426	O75891
GVGIISEGTETAEEV	ATP1A4	636	Q13733
GEVFVLNDGGEVDLD	CTPS2	56	Q9NRF8
GETVEFDVVEGEKGA	YBX2	141	Q9Y2T7
GDGETVEFDVVEGEK	YBX3	136	P16989
GETVEFDVVEGEKGA	YBX1	106	P67809
TILVEGGEIELFDGE	VWF	926	P04275
VELGTAGAGEVQEGD	PKMYT1	256	Q99640
DDIGEIIQVDGSGDT	GTF2A1L	341	Q9UNN4
AGEEDGSLELSAEGV	TBC1D16	206	Q8TBP0
RVGGEESEVTVGGLE	TNXB	2456	P22105
AEVGIGVVAEADAAD	VCL	921	P18206
EEGGGDVDISAGRFV	UNC119B	126	A6NIH7
GEAGDSLVELGDLVV	TLNRD1	106	Q9H1K6
GAAGETIVIEELLDG	GART	181	P22102
EEAGDEIETFGLGVT	MAP2	981	P11137
GDEELGFEAAVAALG	ZSWIM8	951	A7E2V4
GLEVDVFLGAHGEDV	PRR23C	121	Q6ZRP0
GVEGELSFVTLDEIG	ZNF638	1591	Q14966
EFVETEEGGLQKEGL	MYO1G	286	B0I1T2