| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | potassium:chloride symporter activity | 8.34e-05 | 9 | 31 | 2 | GO:0015379 | |
| GeneOntologyMolecularFunction | inorganic anion transmembrane transporter activity | 1.36e-04 | 171 | 31 | 4 | GO:0015103 | |
| GeneOntologyMolecularFunction | ammonium channel activity | 1.52e-04 | 12 | 31 | 2 | GO:0008519 | |
| GeneOntologyMolecularFunction | chloride:monoatomic cation symporter activity | 5.78e-04 | 23 | 31 | 2 | GO:0015377 | |
| GeneOntologyMolecularFunction | monoatomic anion:monoatomic cation symporter activity | 7.41e-04 | 26 | 31 | 2 | GO:0015296 | |
| GeneOntologyMolecularFunction | solute:monoatomic cation symporter activity | 8.21e-04 | 119 | 31 | 3 | GO:0015294 | |
| GeneOntologyMolecularFunction | chloride transmembrane transporter activity | 9.47e-04 | 125 | 31 | 3 | GO:0015108 | |
| GeneOntologyMolecularFunction | symporter activity | 1.60e-03 | 150 | 31 | 3 | GO:0015293 | |
| GeneOntologyMolecularFunction | monoatomic anion transmembrane transporter activity | 1.63e-03 | 151 | 31 | 3 | GO:0008509 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 6.07e-03 | 477 | 31 | 4 | GO:0022804 | |
| GeneOntologyBiologicalProcess | inorganic anion transport | 6.77e-06 | 180 | 31 | 5 | GO:0015698 | |
| GeneOntologyBiologicalProcess | chloride ion homeostasis | 6.91e-06 | 25 | 31 | 3 | GO:0055064 | |
| GeneOntologyBiologicalProcess | monoatomic anion homeostasis | 9.82e-06 | 28 | 31 | 3 | GO:0055081 | |
| GeneOntologyBiologicalProcess | ammonium import across plasma membrane | 1.31e-05 | 4 | 31 | 2 | GO:0140157 | |
| GeneOntologyBiologicalProcess | chloride transport | 3.91e-05 | 128 | 31 | 4 | GO:0006821 | |
| GeneOntologyBiologicalProcess | inorganic anion transmembrane transport | 4.68e-05 | 134 | 31 | 4 | GO:0098661 | |
| GeneOntologyBiologicalProcess | potassium ion import across plasma membrane | 6.10e-05 | 51 | 31 | 3 | GO:1990573 | |
| GeneOntologyBiologicalProcess | monoatomic anion transport | 1.56e-04 | 183 | 31 | 4 | GO:0006820 | |
| GeneOntologyBiologicalProcess | ammonium transmembrane transport | 1.69e-04 | 13 | 31 | 2 | GO:0072488 | |
| GeneOntologyBiologicalProcess | regulation of neuron projection arborization | 2.27e-04 | 15 | 31 | 2 | GO:0150011 | |
| GeneOntologyBiologicalProcess | metal ion transport | 5.82e-04 | 1000 | 31 | 7 | GO:0030001 | |
| GeneOntologyBiologicalProcess | chloride transmembrane transport | 6.27e-04 | 112 | 31 | 3 | GO:1902476 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | 6.44e-04 | 1017 | 31 | 7 | GO:0098660 | |
| GeneOntologyBiologicalProcess | potassium ion transport | 7.03e-04 | 272 | 31 | 4 | GO:0006813 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | 7.52e-04 | 1374 | 31 | 8 | GO:0006811 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | 1.11e-03 | 1115 | 31 | 7 | GO:0034220 | |
| GeneOntologyBiologicalProcess | glomerular filtration | 1.12e-03 | 33 | 31 | 2 | GO:0003094 | |
| GeneOntologyBiologicalProcess | inorganic ion import across plasma membrane | 1.25e-03 | 142 | 31 | 3 | GO:0099587 | |
| GeneOntologyBiologicalProcess | inorganic cation import across plasma membrane | 1.25e-03 | 142 | 31 | 3 | GO:0098659 | |
| GeneOntologyBiologicalProcess | renal filtration | 1.33e-03 | 36 | 31 | 2 | GO:0097205 | |
| GeneOntologyBiologicalProcess | monoatomic cation transport | 1.38e-03 | 1157 | 31 | 7 | GO:0006812 | |
| GeneOntologyBiologicalProcess | potassium ion homeostasis | 1.41e-03 | 37 | 31 | 2 | GO:0055075 | |
| GeneOntologyBiologicalProcess | renal system process | 1.43e-03 | 149 | 31 | 3 | GO:0003014 | |
| GeneOntologyBiologicalProcess | neuron projection arborization | 1.49e-03 | 38 | 31 | 2 | GO:0140058 | |
| GeneOntologyBiologicalProcess | monoatomic anion transmembrane transport | 1.54e-03 | 153 | 31 | 3 | GO:0098656 | |
| Domain | KCL_cotranspt | 1.60e-05 | 4 | 31 | 2 | IPR000076 | |
| Domain | SLC12A_fam | 5.57e-05 | 7 | 31 | 2 | IPR004842 | |
| Domain | SLC12 | 7.42e-05 | 8 | 31 | 2 | PF03522 | |
| Domain | SLC12_C | 7.42e-05 | 8 | 31 | 2 | IPR018491 | |
| Domain | AA-permease/SLC12A_dom | 6.03e-04 | 22 | 31 | 2 | IPR004841 | |
| Domain | AA_permease | 6.03e-04 | 22 | 31 | 2 | PF00324 | |
| Domain | Glycoside_hydrolase_SF | 3.49e-03 | 53 | 31 | 2 | IPR017853 | |
| Domain | SAM/pointed | 1.61e-02 | 117 | 31 | 2 | IPR013761 | |
| Pathway | REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS | 6.83e-05 | 7 | 26 | 2 | M27339 | |
| Pathway | REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS | 6.83e-05 | 7 | 26 | 2 | MM15081 | |
| Pathway | WP_2Q13_COPY_NUMBER_VARIATION_SYNDROME | 2.06e-04 | 63 | 26 | 3 | M45526 | |
| Pubmed | Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney. | 2.46e-06 | 3 | 32 | 2 | 24089410 | |
| Pubmed | 2.46e-06 | 3 | 32 | 2 | 11551954 | ||
| Pubmed | 2.46e-06 | 3 | 32 | 2 | 15262997 | ||
| Pubmed | K-Cl cotransporter gene expression during human and murine erythroid differentiation. | 2.46e-06 | 3 | 32 | 2 | 21733850 | |
| Pubmed | 4.92e-06 | 4 | 32 | 2 | 12637262 | ||
| Pubmed | 2.29e-05 | 8 | 32 | 2 | 11395011 | ||
| Pubmed | The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. | 2.29e-05 | 8 | 32 | 2 | 24393035 | |
| Pubmed | Similar effects of all WNK3 variants on SLC12 cotransporters. | 2.29e-05 | 8 | 32 | 2 | 21613606 | |
| Pubmed | 2.29e-05 | 8 | 32 | 2 | 12386165 | ||
| Pubmed | 2.94e-05 | 9 | 32 | 2 | 19323993 | ||
| Pubmed | USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses. | 3.67e-05 | 10 | 32 | 2 | 25538220 | |
| Pubmed | 7.41e-05 | 14 | 32 | 2 | 32251422 | ||
| Pubmed | Rare independent mutations in renal salt handling genes contribute to blood pressure variation. | 1.87e-04 | 22 | 32 | 2 | 18391953 | |
| Pubmed | Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. | 4.25e-04 | 33 | 32 | 2 | 16870172 | |
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | 6.86e-04 | 440 | 32 | 4 | 34244565 | |
| Pubmed | Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. | 7.57e-04 | 44 | 32 | 2 | 27534441 | |
| Interaction | SLC31A1 interactions | 8.75e-06 | 192 | 30 | 5 | int:SLC31A1 | |
| Cytoband | 2q13 | 1.49e-05 | 68 | 32 | 3 | 2q13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q14 | 2.09e-04 | 165 | 32 | 3 | chr2q14 | |
| GeneFamily | Solute carriers | 1.17e-02 | 395 | 22 | 3 | 752 | |
| CoexpressionAtlas | dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000 | 2.01e-05 | 115 | 30 | 4 | gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k4_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500 | 2.29e-05 | 420 | 30 | 6 | gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500 | |
| CoexpressionAtlas | dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_500 | 6.79e-05 | 157 | 30 | 4 | gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_500 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_200 | 8.42e-05 | 166 | 30 | 4 | gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200 | |
| CoexpressionAtlas | dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000 | 1.03e-04 | 804 | 30 | 7 | gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#3_top-relative-expression-ranked_200 | 1.25e-04 | 69 | 30 | 3 | gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200_k3 | |
| Drug | ((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid | 1.91e-06 | 2 | 32 | 2 | ctd:C095651 | |
| Drug | ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA | 6.12e-06 | 188 | 32 | 5 | 974_UP | |
| Drug | Isoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A | 7.49e-06 | 196 | 32 | 5 | 2056_DN | |
| Drug | Trichlormethiazide | 1.91e-05 | 5 | 32 | 2 | ctd:D014237 | |
| Drug | Potassium Chloride | 2.86e-05 | 6 | 32 | 2 | DB00761 | |
| Disease | Endometrioma | 5.81e-04 | 161 | 30 | 3 | C0269102 | |
| Disease | Endometriosis | 5.81e-04 | 161 | 30 | 3 | C0014175 | |
| Disease | Metastatic melanoma | 1.38e-03 | 54 | 30 | 2 | C0278883 | |
| Disease | smoking behavior | 4.93e-03 | 341 | 30 | 3 | EFO_0004318 | |
| Disease | hypertension (is_implicated_in) | 6.73e-03 | 121 | 30 | 2 | DOID:10763 (is_implicated_in) | |
| Disease | response to bronchodilator, FEV/FEC ratio | 7.22e-03 | 766 | 30 | 4 | EFO_0004713, GO_0097366 | |
| Disease | attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement | 8.43e-03 | 801 | 30 | 4 | EFO_0003888, EFO_0007052, MONDO_0002491 | |
| Disease | Bladder Neoplasm | 8.91e-03 | 140 | 30 | 2 | C0005695 | |
| Disease | Malignant neoplasm of urinary bladder | 9.04e-03 | 141 | 30 | 2 | C0005684 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| MWRAIRTAFKNRKRA | 1471 | Q8WWZ7 | |
| ARRDRMPCRNFFWKT | 86 | O00230 | |
| RLDTFFDPRWRKRMS | 511 | O60477 | |
| ISRFRRWLPKKPMRL | 206 | Q32M45 | |
| IPLGRRFRSLKMWFV | 351 | P20711 | |
| EMKRRVFPFTWRPRH | 426 | O94810 | |
| QKRKESMPRKARRFW | 256 | P55040 | |
| WFQNRRMKKKRLLLR | 261 | P31275 | |
| RSPSWRKMFREKDLR | 1126 | O75145 | |
| LRKRQIRPHWMFVLD | 1091 | O95382 | |
| KPKRWISFKSFFRRR | 921 | Q9H792 | |
| MWPLRVYTRKKREGQ | 1 | A0A087WXM9 | |
| WKKIRQRFVKPRQHM | 231 | P36382 | |
| FRVPREYWRDRLLKM | 71 | Q8IW92 | |
| RQHKVWRKCRMRIFT | 866 | Q9Y666 | |
| VWFFVCPRMKRKIER | 246 | Q8WUM9 | |
| KLVRLKLWFPRFMNV | 196 | Q9BQ95 | |
| KRMLFTGRRQKFSPW | 16 | A6NM36 | |
| RWADVRFPEKRRMKL | 81 | Q9HCE1 | |
| RPWVMEQRKELFRRL | 71 | O60502 | |
| RQHKVWRKCRMRIFT | 866 | Q9UP95 | |
| FMFKFTRREPWIGLR | 146 | P0C7M8 | |
| KPLLWGRMNKYRSLR | 391 | Q70EL2 | |
| AFLRLKRKFIQMRRP | 236 | Q9H2G4 | |
| KTRSRIPLLRKRWFQ | 276 | A0A494C086 | |
| SWPRIIMRFRKRKNF | 166 | Q7Z2W9 | |
| VMRNLFVRKLYLWPR | 181 | Q92889 | |
| RRNFPIAMIRPKWKT | 186 | Q9H9Y6 | |
| HWKRLRRDNPRFNLM | 26 | Q8NG68 | |
| LRRFREMKPRVLQRW | 266 | Q96J92 | |
| QYRQFQRRKWPEMKR | 841 | Q8IWU5 | |
| IRPQRAKMRFWAKGK | 1751 | B2RTY4 |