Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	DCHS2 MYO5A CDHR2 CDH23 CDHR5 CABYR FAT1 FAT2 HMCN2 RPTN PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCLO PCDHA6 CUBN MACF1 UNC13C PLCH1 PCDHGC3 CDH5 CDH12 CDH17	2.71e-07	749	207	25	GO:0005509
GeneOntologyMolecularFunction	cell adhesion molecule binding	CDHR2 OBSCN CDH23 SH3GLB2 CDHR5 ITGA2 ITGA2B PROM1 FASN VWF DOCK9 PPL ICAM5 TLN1 MACF1 SCRIB CDH5 CDH12 CDH17	1.63e-05	599	207	19	GO:0050839
GeneOntologyMolecularFunction	cadherin binding	OBSCN CDH23 SH3GLB2 PROM1 FASN DOCK9 PPL TLN1 MACF1 SCRIB CDH5 CDH12 CDH17	5.66e-05	339	207	13	GO:0045296
GeneOntologyMolecularFunction	tRNA-4-demethylwyosine synthase activity	TYW1B TYW1	1.07e-04	2	207	2	GO:0102521
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 HMCN2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	4.99e-12	187	203	17	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 SLITRK2 HMCN2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	2.19e-09	313	203	18	GO:0098742
GeneOntologyBiologicalProcess	cell-cell adhesion	CYP1B1 DCHS2 ERBB2 CDHR2 ABCA12 CDH23 CDHR5 ITGA2 ITGA2B ITPKB FAT1 FAT2 SLITRK2 HMCN2 PKHD1 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 AKNA AMBRA1 PCDHA6 ICAM5 TLN1 SCRIB PCDHGC3 CDH5 CDH12 CDH17	2.54e-07	1077	203	30	GO:0098609
GeneOntologyBiologicalProcess	epithelial cell development	RAPGEF6 ARID4B ABCA12 FASN TFCP2L1 FAT1 PKHD1 COL27A1 JMJD1C AKAP9 SCRIB CDH5	1.53e-05	269	203	12	GO:0002064
GeneOntologyBiologicalProcess	epithelium development	RAPGEF6 ARID4B MYO5A CDHR2 ABCA12 CCNO CDH23 ITGA2 PROM1 FREM2 FASN TFCP2L1 FAT1 PKHD1 USH2A TCTN1 CCDC40 FAT4 FRAS1 IPO7 COL27A1 COMMD5 AIRE AMBRA1 JMJD1C PPL TGFBR3 AKAP9 PHACTR4 SCRIB CDH5	4.58e-05	1469	203	31	GO:0060429
GeneOntologyBiologicalProcess	epithelial cell differentiation	RAPGEF6 ARID4B CDHR2 ABCA12 CCNO CDH23 ITGA2 PROM1 FASN TFCP2L1 FAT1 PKHD1 USH2A FAT4 IPO7 COL27A1 COMMD5 JMJD1C PPL AKAP9 SCRIB CDH5	5.01e-05	870	203	22	GO:0030855
GeneOntologyBiologicalProcess	intermicrovillar adhesion	CDHR2 CDHR5	9.64e-05	2	203	2	GO:0090675
GeneOntologyBiologicalProcess	epithelial cell morphogenesis	FAT1 PKHD1 COL27A1 JMJD1C SCRIB	1.18e-04	49	203	5	GO:0003382
GeneOntologyCellularComponent	extrinsic component of plasma membrane	CDH23 TOLLIP APOE CUBN PPL AKAP9 SCRIB CDH5 CDH12 CDH17	1.07e-06	137	206	10	GO:0019897
GeneOntologyCellularComponent	extrinsic component of membrane	CDH23 TOLLIP KALRN APOE CUBN PPL AKAP9 KIAA1755 SCRIB CDH5 CDH12 CDH17	3.18e-06	230	206	12	GO:0019898
GeneOntologyCellularComponent	catenin complex	CDH23 CDH5 CDH12 CDH17	2.65e-04	32	206	4	GO:0016342
GeneOntologyCellularComponent	apical part of cell	ERBB2 PLB1 RAPGEF6 CDHR2 CDH23 CDHR5 PROM1 FAT1 PKHD1 USH2A MGAM FAT4 SI CUBN SCRIB OCLN	2.71e-04	592	206	16	GO:0045177
GeneOntologyCellularComponent	sperm end piece	FSIP2 CABYR	2.88e-04	3	206	2	GO:0097229
GeneOntologyCellularComponent	apical plasma membrane	ERBB2 PLB1 RAPGEF6 CDHR2 CDHR5 PROM1 FAT1 PKHD1 USH2A MGAM SI CUBN SCRIB OCLN	3.55e-04	487	206	14	GO:0016324
GeneOntologyCellularComponent	cluster of actin-based cell projections	PLB1 CDHR2 CDH23 CDHR5 PROM1 USH2A SI CUBN KPTN	3.83e-04	223	206	9	GO:0098862
GeneOntologyCellularComponent	actin-based cell projection	ERBB2 MYO5A CDHR2 CDH23 CDHR5 PROM1 FAT1 USH2A CUBN KPTN	4.56e-04	278	206	10	GO:0098858
GeneOntologyCellularComponent	microvillus membrane	CDHR2 CDHR5 PROM1 CUBN	5.20e-04	38	206	4	GO:0031528
GeneOntologyCellularComponent	extrinsic component of external side of plasma membrane	APOE CUBN	5.72e-04	4	206	2	GO:0031232
GeneOntologyCellularComponent	EARP complex	VPS52 VPS50	9.48e-04	5	206	2	GO:1990745
GeneOntologyCellularComponent	postsynapse	ERBB2 MYO5A SH3GLB2 VPS52 SLITRK2 RNF216 PCDH10 KIF17 DAGLA CHRNA6 KALRN PCLO LAMA2 DGKZ KPTN AKAP9 SLC18A2 DROSHA ICAM5 MACF1 SCRIB	1.15e-03	1018	206	21	GO:0098794
GeneOntologyCellularComponent	ciliary transition zone	USH2A KIF17 TCTN1 KIAA1549 CEP131	1.24e-03	81	206	5	GO:0035869
GeneOntologyCellularComponent	basement membrane	FREM1 FREM2 HMCN2 USH2A FRAS1 LAMA2	1.33e-03	122	206	6	GO:0005604
GeneOntologyCellularComponent	periciliary membrane compartment	USH2A KIF17	1.41e-03	6	206	2	GO:1990075
GeneOntologyCellularComponent	cell leading edge	ERBB2 MYO5A FAT1 USH2A DAGLA APBB2 DGKZ KPTN TLN1 PHACTR4 MACF1 SCRIB OCLN	1.44e-03	500	206	13	GO:0031252
GeneOntologyCellularComponent	male germ cell nucleus	MORC1 ACTRT3 BRCA1 AIRE ZFPM2	1.62e-03	86	206	5	GO:0001673
MousePheno	cryptophthalmos	FREM1 FREM2 FRAS1	1.90e-06	3	174	3	MP:0005242
MousePheno	absent eyelids	FREM1 FREM2 FRAS1 SCRIB	1.06e-05	12	174	4	MP:0001341
Domain	Cadherin	DCHS2 CDHR2 CDH23 CDHR5 FREM1 FREM2 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	7.54e-16	118	205	18	IPR002126
Domain	CA	DCHS2 CDHR2 CDH23 CDHR5 FREM2 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	8.47e-15	115	205	17	SM00112
Domain	Cadherin_CS	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	5.99e-14	109	205	16	IPR020894
Domain	CADHERIN_1	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	1.07e-13	113	205	16	PS00232
Domain	CADHERIN_2	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	1.23e-13	114	205	16	PS50268
Domain	-	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	1.23e-13	114	205	16	2.60.40.60
Domain	Cadherin-like	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	1.63e-13	116	205	16	IPR015919
Domain	Cadherin	DCHS2 CDHR2 CDH23 FAT1 FAT2 PCDH10 FAT4 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3 CDH5 CDH12 CDH17	1.70e-12	113	205	15	PF00028
Domain	LAM_G_DOMAIN	FAT1 FAT2 USH2A FAT4 COL27A1 LAMA2	3.35e-06	38	205	6	PS50025
Domain	Laminin_G	FAT1 FAT2 USH2A FAT4 COL27A1 LAMA2	4.09e-05	58	205	6	IPR001791
Domain	Cadherin_tail	PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	4.97e-05	37	205	5	PF15974
Domain	Cadherin_CBD	PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	4.97e-05	37	205	5	IPR031904
Domain	Laminin_G_2	FAT1 FAT2 USH2A FAT4 LAMA2	7.30e-05	40	205	5	PF02210
Domain	Cadherin_2	PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	7.83e-05	65	205	6	PF08266
Domain	Cadherin_N	PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	7.83e-05	65	205	6	IPR013164
Domain	Cadherin_C	PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHGC3	9.28e-05	42	205	5	IPR032455
Domain	Cadherin_C_2	PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHGC3	9.28e-05	42	205	5	PF16492
Domain	Calx_beta	FREM1 FREM2 FRAS1	1.04e-04	9	205	3	IPR003644
Domain	Calx-beta	FREM1 FREM2 FRAS1	1.04e-04	9	205	3	PF03160
Domain	LamG	FAT1 FAT2 USH2A FAT4 LAMA2	1.16e-04	44	205	5	SM00282
Domain	Sec16_CCD	SEC16A SEC16B	1.20e-04	2	205	2	IPR024340
Domain	Sec16	SEC16A SEC16B	1.20e-04	2	205	2	IPR024880
Domain	Sec16	SEC16A SEC16B	1.20e-04	2	205	2	PF12932
Domain	tRNA_wybutosine-synth	TYW1B TYW1	1.20e-04	2	205	2	IPR013917
Domain	Wyosine_form	TYW1B TYW1	1.20e-04	2	205	2	PF08608
Domain	Spectrin_repeat	KALRN CCDC141 PPL MACF1	2.70e-04	29	205	4	IPR002017
Domain	Sec16_C	SEC16A SEC16B	3.57e-04	3	205	2	PF12931
Domain	ACE1_Sec16_Sec31	SEC16A SEC16B	3.57e-04	3	205	2	IPR024298
Domain	-	FAT1 FAT2 USH2A FAT4 LAMA2 WDFY3	6.28e-04	95	205	6	2.60.120.200
Domain	Glyco_hydro_31_CS	MGAM SI	7.09e-04	4	205	2	IPR030459
Domain	Gal_mutarotase_N	MGAM SI	7.09e-04	4	205	2	IPR031727
Domain	NtCtMGAM_N	MGAM SI	7.09e-04	4	205	2	PF16863
Domain	Biotin_BS	ACACB PC	1.17e-03	5	205	2	IPR001882
Domain	GLYCOSYL_HYDROL_F31_2	MGAM SI	1.17e-03	5	205	2	PS00707
Domain	Biotin_COase_C	ACACB PC	1.17e-03	5	205	2	IPR005482
Domain	BC	ACACB PC	1.17e-03	5	205	2	PS50979
Domain	Biotin_carb_C	ACACB PC	1.17e-03	5	205	2	SM00878
Domain	Biotin_carb_C	ACACB PC	1.17e-03	5	205	2	PF02785
Domain	Biotin_carboxylation_dom	ACACB PC	1.17e-03	5	205	2	IPR011764
Domain	BIOTIN	ACACB PC	1.17e-03	5	205	2	PS00188
Domain	Glyco_hydro_31_AS	MGAM SI	1.75e-03	6	205	2	IPR030458
Domain	GAR	GAS2L1 MACF1	1.75e-03	6	205	2	PS51460
Domain	CP2	TFCP2L1 TFCP2	1.75e-03	6	205	2	PF04516
Domain	CP2	TFCP2L1 TFCP2	1.75e-03	6	205	2	IPR007604
Domain	Rudment_hybrid_motif	ACACB PC	1.75e-03	6	205	2	IPR011054
Domain	RIIa	CABYR PRKAR2A	1.75e-03	6	205	2	SM00394
Domain	GAS2	GAS2L1 MACF1	1.75e-03	6	205	2	PF02187
Domain	-	GAS2L1 MACF1	1.75e-03	6	205	2	3.30.920.20
Domain	GAS_dom	GAS2L1 MACF1	1.75e-03	6	205	2	IPR003108
Domain	GAS2	GAS2L1 MACF1	1.75e-03	6	205	2	SM00243
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MON2 MTA2 CAAP1 ERBB2 ARID4B ACTR5 ABCA12 TSPYL2 ZNF518A FAT1 VPS52 HMCN2 BRCA1 SEC16A ANKRD52 RAE1 ARHGAP23 VPS50 KIAA1549 AMBRA1 CHD9 TTC7A DROSHA TBK1 MACF1 WDFY3 MRGBP SCRIB KIF18B	3.41e-11	1116	208	29	31753913
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZBTB38 OBSCN SH3GLB2 BIRC6 MYO18B RABGGTB VWF IPO7 KALRN DOCK9 LAMA2 CCDC141 JMJD1C AKAP9 DROSHA TBK1 TLN1 MACF1	1.46e-09	497	208	18	23414517
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ACACB BIRC6 TASOR2 PTPN3 FAT1 VPS52 BRCA1 SEC16A PCDH10 GOLGB1 IGSF3 SMAP1 FAT4 APBB2 HUWE1 PPL SEC24C PHACTR4 CEP131 SCRIB OCLN PC	2.02e-09	777	208	22	35844135
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ERBB2 RAPGEF6 HDAC4 MATK ITPKB FSIP2 PTPN3 WWC2 SEC16A GOLGB1 EHBP1 ARHGEF5 LARP1B AKAP9 DCP1B PHACTR4 MACF1 CEP131 SCRIB PLCH1 PC SAMD4A AHNAK2	2.56e-09	861	208	23	36931259
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	BIRC6 ZNF518A SEC16A DAGLA PRUNE2 DOCK9 TTC7A TLN1 HELZ2 MACF1 WDFY3 SCRIB	1.30e-08	225	208	12	12168954
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT1 FAT2 FAT4	4.29e-08	7	208	4	16059920
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ERBB2 RAPGEF6 ACACB ITGA2 SEC16A GOLGB1 EHBP1 APBB2 PHACTR4 LRRC1 MACF1 SCRIB OCLN PLCH1 SLC12A7	4.42e-08	421	208	15	36976175
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 MTA2 ERBB2 RAPGEF6 OBSCN BIRC6 FASN FAT1 SEC16A IGSF3 FRAS1 KALRN DOCK9 AKNA AMBRA1 HUWE1 GAS2L1 TLN1 HELZ2 NPRL3 CEP131 WDFY3 PC AHNAK2	5.88e-08	1105	208	24	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAPGEF6 NCAPG2 XAB2 FREM2 RNF216 FRAS1 ARHGAP23 ARHGEF5 AMBRA1 JMJD1C DROSHA TBK1 MARF1 SCRIB PLCH1 SLC12A7 PCDHGC3 RAVER1	8.86e-08	650	208	18	38777146
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MTA2 MYO5A ITGA2 ITPKB FASN HECW2 SEC16A TOLLIP DNAH6 DAGLA SMAP1 VWF ARHGAP23 KALRN PCLO KIAA1549 DGKZ APOE GAS2L1 SEC24C ICAM5 TLN1 PRKAR2A MACF1 SCRIB PLCH1 PC	1.43e-07	1431	208	27	37142655
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 MAP3K4 SEC16A PCDH10 KIF17 FRAS1 DOCK9 VPS8 AKAP9 SEC24C TLN1 GPCPD1 MACF1 SCRIB	1.93e-07	407	208	14	12693553
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	FAT2 PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	2.62e-07	72	208	7	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	CDHR5 PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	3.17e-07	74	208	7	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	FAT2 PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	4.17e-07	77	208	7	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	FAT2 PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	5.43e-07	80	208	7	10716726
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	OBSCN ZNF226 BIRC6 FREM2 SAMD9L HECW2 PKHD1 PCDH10 FAT4 PCDHGB3 PCLO HUWE1 ADO DROSHA TBK1 TLN1 SCRIB RBM41	5.44e-07	736	208	18	29676528
Pubmed	The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia.	FREM1 FREM2 FRAS1	8.40e-07	4	208	3	29618029
Pubmed	Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.	FREM1 FREM2 FRAS1	8.40e-07	4	208	3	23221805
Pubmed	Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.	FREM1 FREM2 FRAS1	8.40e-07	4	208	3	36495293
Pubmed	Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.	FREM1 FREM2 FRAS1	8.40e-07	4	208	3	18563433
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CDHR2 CDHR5 PROM1 FASN FAT1 PKHD1 PGLS TOLLIP MNDA NAA16 VWF KALRN VPS50 HUWE1 APOE CUBN PPL TGFBR3 TLN1 SERPINB1 PRKAR2A	9.23e-07	1016	208	21	19056867
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CAAP1 RAPGEF6 ARID4B MATK WWC2 PPIG FASN SEC16A SEC16B HUWE1 TFAP4 PPL SEC24C PHACTR4 HELZ2 SCRIB CDH17 RAVER1	1.12e-06	774	208	18	15302935
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAPGEF6 ACACB BIRC6 FASN SEC16A ANKRD52 GOLGB1 EHBP1 HUWE1 JMJD1C TBK1 CEP131 PC	1.64e-06	418	208	13	34709266
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BIRC6 FAT2 SAMD9L PRUNE2 EHBP1 SEC16B ARHGAP23 COL27A1 ATP10A JMJD1C HELZ2 MACF1 PLCH1 NEURL4	1.88e-06	493	208	14	15368895
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	CDHR5 ITGA2 PROM1 PTPN3 FAT1 SLITRK2 NRK IGSF3 EHBP1 DOCK9 KIAA1549 PHACTR4 SCRIB OCLN SLC12A7	2.00e-06	569	208	15	30639242
Pubmed	Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.	DNAH6 CCDC40 DNAH1	2.09e-06	5	208	3	39056782
Pubmed	Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.	ITGA2 ITGA2B TLN1	2.09e-06	5	208	3	18086863
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FREM1 FREM2 FRAS1	2.09e-06	5	208	3	23536828
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FREM1 FREM2 FRAS1	2.09e-06	5	208	3	17596926
Pubmed	Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.	FREM1 FREM2 FRAS1	2.09e-06	5	208	3	17251066
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CDH23 PPIG FAT1 SAMD9L HMCN2 MYO18B DNAH6 SEC16B SMCHD1 ATP10A JMJD1C MACF1	2.09e-06	361	208	12	26167880
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RAPGEF6 HDAC4 ACACB SH3GLB2 BIRC6 SEC16A ANKRD52 RAE1 KIAA1549 AKAP9 TBK1 CEP131 SAMD4A	3.32e-06	446	208	13	24255178
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDH10 PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	3.42e-06	68	208	6	11230163
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ERBB2 HDAC4 MYO5A TSPYL2 OBSCN TASOR2 ITPKB DAGLA GOLGB1 PRUNE2 EHBP1 APBB2 CHD9 MSH5 HUWE1 NAALADL2 ATP10A JMJD1C TFAP4 DNAH1 TBK1 LRRC1 MACF1 NRG3 RAVER1	3.49e-06	1489	208	25	28611215
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FREM1 FREM2 FRAS1 LAMA2	3.56e-06	18	208	4	14730302
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CDH23 FREM1 FAT2 FRAS1 COL27A1 AKAP9 MACF1 PC	4.01e-06	152	208	8	34299191
Pubmed	Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.	FREM1 FREM2 FRAS1	4.16e-06	6	208	3	24700879
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	FREM1 FREM2 FRAS1	4.16e-06	6	208	3	17462874
Pubmed	Identification of Erbin interlinking MuSK and ErbB2 and its impact on acetylcholine receptor aggregation at the neuromuscular junction.	ERBB2 LRRC1 SCRIB	4.16e-06	6	208	3	20463225
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MON2 SAAL1 MYO5A BIRC6 PHKA1 PTPN3 WWC2 SEC16A ANKRD52 IPO7 KIAA1549 HUWE1 AKAP9 LRRC1 CEP131 SCRIB PC SLC12A7 NEURL4 RAVER1	5.68e-06	1049	208	20	27880917
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARID4B ACACB ORC6 NAP1L3 ITPKB ANKRD52 IGSF3 FAT4 IPO7 PRELP SERPINB1 WDFY3 CDH17 AHNAK2 RAVER1	7.91e-06	638	208	15	31182584
Pubmed	Defining the membrane proteome of NK cells.	CALCOCO2 MTA2 MYO5A ORC6 BIRC6 NCAPG2 XAB2 FASN GOLGB1 IPO7 DOCK9 VPS50 AKNA HUWE1 APOE DCP1B HELZ2 MARF1 SERPINB1 PRKAR2A ITPRIP	8.01e-06	1168	208	21	19946888
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FREM1 FREM2 HMCN2 FRAS1 VWF COL27A1 LAMA2 PRELP	8.03e-06	167	208	8	22159717
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ERBB2 SH3GLB2 FASN GOLGB1 EHBP1 ARHGAP23 DOCK9 PPL TTC7A TLN1 PHACTR4 MACF1 SCRIB OCLN	8.90e-06	565	208	14	25468996
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MTA2 CAAP1 XAB2 PPIG FASN GCLM SEC16A SEC16B IPO7 RAE1 SMCHD1 LARP1B TFCP2 AKAP9 SEC24C DROSHA TBK1 TLN1 HELZ2 MARF1 CEP131 MRGBP PC	8.93e-06	1371	208	23	36244648
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MTA2 MYO5A BIRC6 XAB2 TASOR2 FASN SEC16A ANKRD52 IPO7 SMCHD1 HUWE1 SEC24C TLN1 HELZ2 MACF1	1.04e-05	653	208	15	22586326
Pubmed	Importance of Endogenous Atrial and Brain Natriuretic Peptides in Murine Embryonic Vascular and Organ Development.	NPR1 VWF CDH5	1.15e-05	8	208	3	26517044
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	RAPGEF6 HDAC4 ACACB TSPYL2 TASOR2 PRR14 PRUNE2 IPO7 ARHGEF5 CCDC141 TLN1 NEURL4	1.23e-05	430	208	12	35044719
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 SH3GLB2 RMI1 SEC16A ANKRD52 GOLGB1 RAE1 VPS50 HUWE1 ADO DROSHA TBK1 MACF1 CEP131	1.39e-05	588	208	14	38580884
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	FREM1 FREM2 FRAS1	2.45e-05	10	208	3	15345741
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RAPGEF6 FASN SEC16A GOLGB1 IPO7 JMJD1C TLN1 SCRIB AHNAK2	2.60e-05	256	208	9	33397691
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FREM1 FREM2 FRAS1 LAMA2	2.63e-05	29	208	4	22613833
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ERBB2 FASN GCLM SEC16A GOLGB1 EHBP1 IPO7 JMJD1C SEC24C TLN1 PHACTR4 MACF1 SCRIB OCLN PLCH1	2.66e-05	708	208	15	39231216
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MTA2 RAPGEF6 FASN SEC16A SMCHD1 HUWE1 APOE JMJD1C ICAM5 TLN1 PHACTR4 SCRIB PC	2.99e-05	549	208	13	38280479
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZMYND19 SAAL1 RAPGEF6 OBSCN WWC2 KCNJ8 SEC16A TOLLIP GOLGB1 DOCK9 DGKZ MSH5 HUWE1 CUBN SEC24C TYW1B ITPRIP MACF1 TYW1	3.12e-05	1084	208	19	11544199
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	SEC16A GOLGB1 EHBP1 KIAA1549 JMJD1C MACF1 SCRIB OCLN AHNAK2	3.22e-05	263	208	9	34702444
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 ZBTB38 MYO5A TSPYL2 NAP1L3 SH3GLB2 XAB2 TOLLIP RNF216 VWF KALRN APBB2 AIRE CHD9 HUWE1 APOE DROSHA MACF1 WDFY3 SCRIB PC	3.28e-05	1285	208	21	35914814
Pubmed	Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.	FAT1 FAT4 SCRIB	3.36e-05	11	208	3	26114487
Pubmed	VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.	CALCOCO2 TOLLIP TBK1	3.36e-05	11	208	3	37352355
Pubmed	Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer.	ERBB2 MATK	3.56e-05	2	208	2	12122014
Pubmed	655Val and 1170Pro ERBB2 SNPs in familial breast cancer risk and BRCA1 alterations.	ERBB2 BRCA1	3.56e-05	2	208	2	17452776
Pubmed	HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway.	BRCA1 HUWE1	3.56e-05	2	208	2	24342616
Pubmed	Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.	ERBB2 FASN	3.56e-05	2	208	2	26107737
Pubmed	Increased atherosclerosis and smooth muscle cell hypertrophy in natriuretic peptide receptor A-/-apolipoprotein E-/- mice.	NPR1 APOE	3.56e-05	2	208	2	12702516
Pubmed	Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.	ERBB2 FASN	3.56e-05	2	208	2	27714708
Pubmed	HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway.	BRCA1 HUWE1	3.56e-05	2	208	2	24472556
Pubmed	Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation.	TFCP2L1 TFCP2	3.56e-05	2	208	2	20661472
Pubmed	Platelet collagen receptor alpha2beta1 integrin and glycoprotein IIIa Pl(A1/A2) polymorphisms are not associated with nephropathy in type 2 diabetes.	ITGA2 ITGA2B	3.56e-05	2	208	2	11728949
Pubmed	Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.	CYP1B1 APOE	3.56e-05	2	208	2	27301358
Pubmed	Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.	TGM6 FAT2	3.56e-05	2	208	2	29053796
Pubmed	Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development.	FREM1 FRAS1	3.56e-05	2	208	2	17240369
Pubmed	Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.	TYW1B TYW1	3.56e-05	2	208	2	16162496
Pubmed	Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies.	ITGA2B VWF	3.56e-05	2	208	2	18084279
Pubmed	A homozygous mutation p.Arg2167Trp in FREM2 causes isolated cryptophthalmos.	FREM1 FREM2	3.56e-05	2	208	2	29688405
Pubmed	Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice.	GCLM APOE	3.56e-05	2	208	2	21868708
Pubmed	A myosin family tree.	MYO5A CDH23	3.56e-05	2	208	2	10984423
Pubmed	Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.	MGAM SI	3.56e-05	2	208	2	27480812
Pubmed	Toll-interacting protein deficiency promotes neurodegeneration via impeding autophagy completion in high-fat diet-fed ApoE-/- mouse model.	TOLLIP APOE	3.56e-05	2	208	2	27720815
Pubmed	Tollip Deficiency Alters Atherosclerosis and Steatosis by Disrupting Lipophagy.	TOLLIP APOE	3.56e-05	2	208	2	28396568
Pubmed	FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.	ERBB2 FASN	3.56e-05	2	208	2	26936618
Pubmed	Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer.	ERBB2 FASN	3.56e-05	2	208	2	25433947
Pubmed	Myeloid-Specific Deletion of Diacylglycerol Lipase α Inhibits Atherogenesis in ApoE-Deficient Mice.	DAGLA APOE	3.56e-05	2	208	2	26731274
Pubmed	LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling.	LRRC1 MACF1	3.56e-05	2	208	2	38165568
Pubmed	Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.	FREM2 FRAS1	3.56e-05	2	208	2	21900877
Pubmed	Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.	CDHR2 CDHR5	3.56e-05	2	208	2	34871294
Pubmed	The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway.	LRRC1 SCRIB	3.56e-05	2	208	2	31513346
Pubmed	Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.	ERBB2 FASN	3.56e-05	2	208	2	25674245
Pubmed	[Expressions of integrinalpha2beta1 and CD133 in benign prostatic hyperplasia complicated by prostatitis and their significance].	ITGA2 PROM1	3.56e-05	2	208	2	22049795
Pubmed	Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.	OBSCN PRUNE2	3.56e-05	2	208	2	17360660
Pubmed	Molecular study of 33 families with Fraser syndrome new data and mutation review.	FREM2 FRAS1	3.56e-05	2	208	2	18671281
Pubmed	Platelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIb.	ITGA2B APOE	3.56e-05	2	208	2	16103235
Pubmed	Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.	ERBB2 FASN	3.56e-05	2	208	2	15235125
Pubmed	Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.	FREM2 FRAS1	3.56e-05	2	208	2	32643034
Pubmed	Differential expression of fatty acid synthase (FAS) and ErbB2 in nonmalignant and malignant oral keratinocytes.	ERBB2 FASN	3.56e-05	2	208	2	18528705
Pubmed	Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.	CDH23 USH2A	3.56e-05	2	208	2	17360538
Pubmed	A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-∆11q splice variant.	BRCA1 HUWE1	3.56e-05	2	208	2	37491606
Pubmed	Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.	MGAM SI	3.56e-05	2	208	2	36968271
Pubmed	Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis.	ITGA2B VWF	3.56e-05	2	208	2	1737795
Pubmed	Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence.	ITGA2B TLN1	3.56e-05	2	208	2	17872456
Pubmed	Expression status of fatty acid synthase (FAS) but not HER2 is correlated with the differentiation grade and prognosis of esophageal carcinoma.	ERBB2 FASN	3.56e-05	2	208	2	23419663
Interaction	PFN1 interactions	MON2 CALCOCO2 RAPGEF6 MYO5A BIRC6 PHKA1 PPIG FASN BRCA1 SEC16A TOLLIP GOLGB1 PCLO AKAP9 DCP1B PRKAR2A MACF1 CEP131 AHNAK2	1.29e-06	509	206	19	int:PFN1
Interaction	XAGE1A interactions	TSPYL2 FREM2 FAT1 FAT4 FRAS1 PCDHGC3	3.54e-06	41	206	6	int:XAGE1A
Interaction	CEACAM8 interactions	GLB1L FREM2 FAT1 IGSF3 FAT4 FRAS1 KIAA1549 APOE TYW1	3.75e-06	119	206	9	int:CEACAM8
Interaction	GOLGA1 interactions	MON2 RAPGEF6 BIRC6 VPS52 SEC16A ANKRD52 GOLGB1 MACF1 CEP131 AHNAK2	1.95e-05	183	206	10	int:GOLGA1
GeneFamily	Cadherin related	DCHS2 CDHR2 CDH23 CDHR5 FAT1 FAT2 FAT4	1.82e-11	17	133	7	24
GeneFamily	Clustered protocadherins	PCDHGB7 PCDHGB5 PCDHGB3 PCDHA6 PCDHGC3	1.08e-04	64	133	5	20
GeneFamily	PDZ domain containing	RAPGEF6 PTPN3 ARHGAP23 PCLO SCRIB AHNAK2	9.13e-04	152	133	6	1220
GeneFamily	EF-hand domain containing\|Plakins	PPL MACF1	1.46e-03	8	133	2	939
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ITGA2B BRCA1 AKAP9 PHACTR4 MARF1 OCLN	2.23e-03	181	133	6	694
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	HECW2 TOLLIP PCLO	2.33e-03	36	133	3	823
Coexpression	SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN	ACACB ABCA12 PROM1 FREM2 TFCP2L1 PXDNL COL27A1 TGFBR3 AHNAK2	1.16e-05	175	208	9	M6750
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	ZBTB38 PKHD1 GOLGB1 PRUNE2 EHBP1 FRAS1 PCLO CHD9 CUBN WDFY3	1.16e-05	221	208	10	M39222
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 OBSCN FREM1 FREM2 FAT1 SLITRK2 NRK PKHD1 USH2A PCDH10 MGAM FAT4 FRAS1 KALRN PCLO DNAH1 UNC13C PLCH1	8.70e-19	184	208	18	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 OBSCN FREM1 FREM2 FAT1 SLITRK2 NRK PKHD1 USH2A PCDH10 MGAM FAT4 FRAS1 KALRN PCLO DNAH1 UNC13C PLCH1	8.70e-19	184	208	18	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 OBSCN FREM1 FREM2 FAT1 SLITRK2 NRK PKHD1 USH2A PCDH10 MGAM FAT4 FRAS1 KALRN PCLO DNAH1 UNC13C PLCH1	8.70e-19	184	208	18	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 NALCN PKHD1 USH2A DNAH6 FRAS1 PCLO APOE CUBN DNAH1 UNC13C PLCH1	2.79e-11	169	208	12	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ERBB2 FREM2 TFCP2L1 PKHD1 PCDH10 TRABD2A FRAS1 COL27A1 KIAA1549 TBK1 UNC13C	1.26e-09	185	208	11	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MON2 ARID4B TSPYL2 BIRC6 TASOR2 GOLGB1 SMCHD1 HUWE1 JMJD1C GPCPD1 MACF1	1.49e-09	188	208	11	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 OBSCN SLITRK2 HECW2 KALRN DOCK9 ZFPM2 TGFBR3 NRG3 CDH5	2.31e-08	190	208	10	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	MON2 RAPGEF6 ARID4B HDAC4 TSPYL2 SMCHD1 DOCK9 JMJD1C GPCPD1 MACF1	2.56e-08	192	208	10	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FAT1 HMCN2 PXDNL NRK IGSF3 PRUNE2 LAMA2 ATP10A PRELP AHNAK2	3.11e-08	196	208	10	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ACACB PROM1 NRK MROH7 COL27A1 DNAH1 PRELP WDFY3 AHNAK2	1.66e-07	178	208	9	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYP24A1 PROM1 FAT1 PKHD1 PRUNE2 FRAS1 COL27A1 KIAA1549 CUBN	2.10e-07	183	208	9	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNFRSF10D PROM1 SAMD9L VWF ARHGEF5 ATP10A HELZ2 OCLN CDH5	2.10e-07	183	208	9	c7fc96ac1d5d31ccefe0c1fc6ec76c7d8607a172
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNFRSF10D PROM1 SAMD9L VWF ARHGEF5 ATP10A HELZ2 OCLN CDH5	2.10e-07	183	208	9	6cdadb3ece45a94a2915063aa461048e1d371ccd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNFRSF10D PROM1 SAMD9L VWF ARHGEF5 ATP10A HELZ2 OCLN CDH5	2.10e-07	183	208	9	8714d3e7663c93cdf9b25b647353572e136f30c3
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CYP1B1 DCHS2 DAGLA IGSF3 EHBP1 IPO7 DOCK9 PPL AHNAK2	2.20e-07	184	208	9	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB38 CDHR2 CDHR5 PKHD1 PRUNE2 CUBN KIAA1755 PLPP4 PC	2.42e-07	186	208	9	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 FAT1 PKHD1 PRUNE2 COL27A1 CUBN NRG3 PLCH1 SAMD4A	2.42e-07	186	208	9	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 FREM1 ITPKB TFCP2L1 NRK PKHD1 FRAS1 APBB2 NAALADL2	2.77e-07	189	208	9	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 PTPN3 TFCP2L1 PKHD1 FRAS1 PPL NRG3 OCLN SAMD4A	2.77e-07	189	208	9	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 FREM1 ITPKB TFCP2L1 NRK PKHD1 FRAS1 APBB2 NAALADL2	2.77e-07	189	208	9	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 PTPN3 TFCP2L1 PKHD1 FRAS1 PPL NRG3 OCLN SAMD4A	2.77e-07	189	208	9	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HECW2 FAT4 VWF KALRN DOCK9 TGFBR3 LRRC1 ITPRIP NRG3	2.89e-07	190	208	9	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM1 PROM1 NALCN PXDNL COL27A1 APOE ZFPM2 TGFBR3 PRELP	3.02e-07	191	208	9	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	CDH23 TNFRSF10D ITPKB VWF KALRN DOCK9 APBB2 NRG3 CDH5	3.02e-07	191	208	9	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FREM1 PROM1 FREM2 PTPN3 TFCP2L1 PKHD1 FRAS1 NAALADL2 PLPP4	3.16e-07	192	208	9	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN3 TFCP2L1 FAT1 PKHD1 PRUNE2 FRAS1 PCLO CUBN NAALADL2	3.30e-07	193	208	9	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 FREM2 PTPN3 TFCP2L1 FAT1 PKHD1 FRAS1 PCLO NAALADL2	3.45e-07	194	208	9	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPKB HECW2 FAT4 VWF DOCK9 APBB2 ZFPM2 MACF1 CDH5	3.45e-07	194	208	9	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HECW2 FAT4 VWF KALRN DOCK9 ZFPM2 TGFBR3 NRG3 CDH5	3.60e-07	195	208	9	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 PTPN3 TFCP2L1 FAT1 PKHD1 FRAS1 NAALADL2 PPL UNC13C	3.76e-07	196	208	9	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 FREM2 PTPN3 TFCP2L1 FAT1 PKHD1 FRAS1 PCLO NAALADL2	3.76e-07	196	208	9	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYP24A1 PTPN3 TFCP2L1 FAT1 PKHD1 PRUNE2 FRAS1 NAALADL2 NRG3	3.92e-07	197	208	9	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ITGA2 FAT4 NPR1 VWF DOCK9 JMJD1C GPCPD1 MACF1 CDH5	4.45e-07	200	208	9	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARID4B BIRC6 SAMD9L GOLGB1 SMCHD1 JMJD1C AKAP9 HELZ2 MACF1	4.45e-07	200	208	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	CYP1B1 PLB1 ITPKB SAMD9L FRAS1 APOE TGFBR3 PRELP SERPINB1	4.45e-07	200	208	9	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ERBB2 ITGA2 PTPN3 FAT2 GOLGB1 PCLO PPL AKAP9 AHNAK2	4.45e-07	200	208	9	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	CYP1B1 PLB1 ITPKB SAMD9L FRAS1 APOE TGFBR3 PRELP SERPINB1	4.45e-07	200	208	9	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB2 ITGA2 PTPN3 FAT2 GOLGB1 PCLO PPL AKAP9 AHNAK2	4.45e-07	200	208	9	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT2 PCDH10 PRUNE2 ZCCHC18 LAMA2 ZFPM2 TGFBR3 PRELP	6.35e-07	153	208	8	1524557514668f515ac1bbe847611f564b265b42
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CYP1B1 NALCN HECW2 KCNJ8 NRK ATP10A ZFPM2 NRG3	6.67e-07	154	208	8	511923b27469ea20f8bd82a9ec27119a6e884644
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	OBSCN HECW2 VWF ARHGAP23 KALRN TGFBR3 NRG3 CDH5	1.23e-06	167	208	8	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K4 FASN PCDH10 FAT4 COL27A1 LAMA2 ZFPM2 ICAM5	1.47e-06	171	208	8	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RAPGEF6 TSPYL2 GOLGB1 SMCHD1 AKNA JMJD1C AKAP9 MACF1	1.47e-06	171	208	8	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K4 FASN PCDH10 FAT4 COL27A1 LAMA2 ZFPM2 ICAM5	1.47e-06	171	208	8	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	HDAC4 NAP1L3 NALCN GOLGB1 MARF1 WDFY3 NRG3 PC	1.90e-06	177	208	8	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 FREM1 ITPKB TFCP2L1 NRK FRAS1 APBB2 NAALADL2	2.07e-06	179	208	8	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NALCN FAT4 COL27A1 LAMA2 ZFPM2 TGFBR3 PRELP UNC13C	2.16e-06	180	208	8	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYP1B1 DCHS2 PROM1 FAT1 NALCN NPR1 ZFPM2 NRG3	2.25e-06	181	208	8	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NALCN NRK PRUNE2 FAT4 LAMA2 TGFBR3 PRELP KIAA1755	2.25e-06	181	208	8	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYP1B1 DCHS2 PROM1 FAT1 NALCN NPR1 ZFPM2 NRG3	2.25e-06	181	208	8	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 HECW2 KALRN DOCK9 ZFPM2 TGFBR3 NRG3 CDH5	2.34e-06	182	208	8	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PROM1 PTPN3 TFCP2L1 PKHD1 PRUNE2 FRAS1 PCLO CUBN	2.34e-06	182	208	8	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 FREM1 ITPKB TFCP2L1 NRK FRAS1 APBB2 UNC13C	2.44e-06	183	208	8	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	CYP24A1 FAT1 PKHD1 PRUNE2 SEC16B COL27A1 KIAA1549 CUBN	2.54e-06	184	208	8	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYP1B1 HMCN2 PXDNL LAMA2 ZFPM2 TGFBR3 PRELP KIAA1755	2.64e-06	185	208	8	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	KIF17 SEC16B FAT4 NPR1 VWF DOCK9 LRRC1 CDH5	2.86e-06	187	208	8	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PROM1 PTPN3 TFCP2L1 PKHD1 PRUNE2 FRAS1 PCLO CUBN	2.86e-06	187	208	8	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYP1B1 FREM1 HMCN2 LAMA2 ZFPM2 TGFBR3 PRELP KIAA1755	2.98e-06	188	208	8	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	HECW2 VWF KALRN DOCK9 ZFPM2 TGFBR3 LRRC1 NRG3	2.98e-06	188	208	8	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	ITGA2 ITPKB PTPN3 TFCP2L1 NRK PKHD1 APBB2 NAALADL2	2.98e-06	188	208	8	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	HECW2 VWF KALRN DOCK9 TGFBR3 ITPRIP NRG3 CDH5	2.98e-06	188	208	8	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TNFRSF10D ITGA2 KIF17 NPR1 VWF DOCK9 NRG3 CDH5	2.98e-06	188	208	8	986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	NPR1 VWF ARHGAP23 KALRN ZFPM2 LRRC1 NRG3 CDH5	3.10e-06	189	208	8	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PROM1 FAT1 PKHD1 DNAH6 PRUNE2 NPR1 PPL WDFY3	3.10e-06	189	208	8	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MON2 ACACB TSPYL2 TFCP2L1 GOLGB1 MGAM FRAS1 KIAA1549	3.10e-06	189	208	8	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CYP24A1 FAT1 PKHD1 PRUNE2 COL27A1 CUBN NRG3 SAMD4A	3.10e-06	189	208	8	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|World / Lineage and Cell class	MORC1 ITGA2 ITGA2B VWF KALRN ZFPM2 GAS2L1 SLC18A2	3.22e-06	190	208	8	1d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KREMEN1 FREM2 PKHD1 FRAS1 PCLO PPL OCLN PLCH1	3.22e-06	190	208	8	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HECW2 FAT4 KALRN DOCK9 ZFPM2 TGFBR3 NRG3 CDH5	3.22e-06	190	208	8	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	IPF-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	PTPN3 HECW2 KALRN DOCK9 ZFPM2 LRRC1 NRG3 CDH5	3.22e-06	190	208	8	ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM1 NRK IGSF3 VWF PPL SLC18A2 LRRC1 OCLN	3.35e-06	191	208	8	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ACACB OBSCN PXDNL MYO18B LAMA2 CCDC141 ZFPM2 SAMD4A	3.35e-06	191	208	8	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MON2 BIRC6 SMCHD1 HUWE1 GPCPD1 MACF1 TYW1 POLQ	3.35e-06	191	208	8	9454f642c3621370fa23640b631301346b300950
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	FREM2 PTPN3 FASN TFCP2L1 PCLO CCDC141 NAALADL2 PLCH1	3.35e-06	191	208	8	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HECW2 FAT4 KALRN DOCK9 ZFPM2 TGFBR3 NRG3 CDH5	3.35e-06	191	208	8	f229abf69a1217194f74b0502486907e07dba989
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	CDH23 ITPKB VWF KALRN DOCK9 APBB2 NRG3 CDH5	3.48e-06	192	208	8	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	IPF-Endothelial-Lymphatic\|IPF / Disease state, Lineage and Cell class	PTPN3 HECW2 KALRN DOCK9 ZFPM2 LRRC1 NRG3 CDH5	3.48e-06	192	208	8	2496edd8f3a41146d418879de9ee2ccc7857431f
ToppCell	Control-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	PTPN3 HECW2 ARHGAP23 KALRN ZFPM2 LRRC1 NRG3 CDH5	3.48e-06	192	208	8	f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KREMEN1 FREM2 PKHD1 FRAS1 PCLO PPL OCLN PLCH1	3.48e-06	192	208	8	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VWF KALRN DOCK9 ZFPM2 TGFBR3 LRRC1 NRG3 CDH5	3.62e-06	193	208	8	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA2 ITPKB HECW2 FAT4 VWF DOCK9 GPCPD1 CDH5	3.62e-06	193	208	8	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	COPD-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	PTPN3 HECW2 ARHGAP23 KALRN DOCK9 ZFPM2 LRRC1 CDH5	3.62e-06	193	208	8	25bdc557055b5bce6a21f8696b48e991c696b979
ToppCell	COPD-Endothelial-Lymphatic\|COPD / Disease state, Lineage and Cell class	PTPN3 HECW2 ARHGAP23 KALRN DOCK9 ZFPM2 LRRC1 CDH5	3.62e-06	193	208	8	18bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPKB HECW2 FAT4 NPR1 VWF DOCK9 PHACTR4 CDH5	3.62e-06	193	208	8	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPKB HECW2 FAT4 NPR1 VWF DOCK9 PHACTR4 CDH5	3.62e-06	193	208	8	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	NPR1 VWF KALRN DOCK9 TGFBR3 LRRC1 NRG3 CDH5	3.62e-06	193	208	8	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 FREM2 PTPN3 TFCP2L1 FAT1 PKHD1 FRAS1 PCLO	3.76e-06	194	208	8	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KREMEN1 FREM2 PKHD1 FRAS1 PCLO PPL OCLN PLCH1	3.76e-06	194	208	8	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN HECW2 FAT4 VWF DOCK9 KIAA1549 TGFBR3 CDH5	3.76e-06	194	208	8	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	HECW2 VWF ARHGAP23 KALRN DOCK9 ZFPM2 NRG3 CDH5	3.76e-06	194	208	8	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN3 TFCP2L1 FAT1 PKHD1 PRUNE2 FRAS1 CUBN PHACTR4	3.76e-06	194	208	8	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	background-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HECW2 NPR1 VWF KALRN TGFBR3 ITPRIP NRG3 CDH5	3.90e-06	195	208	8	c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCell	proximal-Endothelial-Vein\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP1B1 TNFRSF10D FAT4 VWF TYW1B ITPRIP CDH5 NEURL4	3.90e-06	195	208	8	0aebdd635a956dd2367883c1cf73d73ce9790635
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGA2 NUDT8 FAT2 ARHGAP23 ARHGEF5 PPL SERPINB1 AHNAK2	3.90e-06	195	208	8	24d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	ITPKB VWF KALRN SMCHD1 DOCK9 ITPRIP MACF1 CDH5	3.90e-06	195	208	8	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	proximal-3-Endothelial-Vein\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP1B1 TNFRSF10D FAT4 VWF TYW1B ITPRIP CDH5 NEURL4	3.90e-06	195	208	8	c81eb541c15b866f9b6ca6a5f1751c5f1243f4fb
ToppCell	proximal-Endothelial-Vein-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP1B1 TNFRSF10D FAT4 VWF TYW1B ITPRIP CDH5 NEURL4	3.90e-06	195	208	8	df00f94facc5d6107aac83cef3c64fefc7f8e562
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 PROM1 PTPN3 TFCP2L1 PKHD1 FRAS1 PCLO NAALADL2	3.90e-06	195	208	8	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 ZBTB38 LAMA2 CHD9 JMJD1C TGFBR3 AKAP9 PRELP	3.90e-06	195	208	8	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLB1 TSPYL2 NAP1L3 CUBN PPL NEURL4 AHNAK2	3.96e-06	138	208	7	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	ARID4B RNF216 EHBP1 DOCK9 APBB2 AMBRA1 CHD9 JMJD1C LRRC1 WDFY3 PLCH1	5.93e-07	174	207	11	7530_DN
Drug	N-ethyl-N-nitrosourea	MTA2 ERBB2 ABCA12 CCNO ITGA2B MAP3K4 ITPKB KCNJ8 VWF SMCHD1 ZFPM2 NRG3 POLQ	1.53e-06	275	207	13	CID000012967
Disease	venous thromboembolism, fibrinogen measurement	DCHS2 RAPGEF6 VWF CHD9 DGKZ JMJD1C ZFPM2	4.17e-07	67	204	7	EFO_0004286, EFO_0004623
Disease	Fraser syndrome (implicated_via_orthology)	FREM1 FREM2 FRAS1	1.30e-06	4	204	3	DOID:0090001 (implicated_via_orthology)
Disease	von Willebrand's disease 1 (is_implicated_in)	ITGA2 ITGA2B VWF	1.30e-06	4	204	3	DOID:0060573 (is_implicated_in)
Disease	urate measurement, bone density	PLB1 ACTR5 FREM1 ITPKB FSIP2 A2ML1 SEC16A VWA3B USH2A FRAS1 NAALADL2 PPL DNAH1 HELZ2 KIAA1755 PRKAR2A CDH12	1.64e-06	619	204	17	EFO_0003923, EFO_0004531
Disease	Unilateral agenesis of kidney	FREM1 FREM2 FRAS1	1.78e-05	8	204	3	C0266294
Disease	platelet component distribution width	KREMEN1 ITGA2 ITGA2B ZPR1 CCDC40 PRUNE2 VWF KALRN DOCK9 APOE CUBN JMJD1C ZFPM2 ADO TLN1 MACF1 SLC12A7	2.20e-05	755	204	17	EFO_0007984
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB BIRC6 RMI1 ZPR1 SEC16B APOE JMJD1C DNAH1 TYW1B MACF1	2.44e-05	276	204	10	EFO_0004612, EFO_0020943
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	ZPR1 DAGLA APOE JMJD1C NRG3	2.47e-05	50	204	5	EFO_0010732
Disease	von Willebrand's disease 2 (is_implicated_in)	ITGA2 VWF	4.76e-05	2	204	2	DOID:0060574 (is_implicated_in)
Disease	Marles Greenberg Persaud syndrome	FREM1 FREM2	4.76e-05	2	204	2	C1855425
Disease	Malignant neoplasm of breast	CYP1B1 ERBB2 HDAC4 CYP24A1 OBSCN FASN BRCA1 MROH7 GOLGB1 EHBP1 VWF KALRN LAMA2 PANX2 CUBN AKAP9 ICAM5 MACF1 OCLN CDH5	6.09e-05	1074	204	20	C0006142
Disease	Disorder of eye	CYP1B1 CDH23 FREM1 PROM1 FREM2 USH2A TCTN1 FRAS1	1.21e-04	212	204	8	C0015397
Disease	Proteinuria	VWF CUBN UNC13C	1.39e-04	15	204	3	HP_0000093
Disease	Glanzmann's thrombasthenia (is_implicated_in)	ITGA2 ITGA2B	1.42e-04	3	204	2	DOID:2219 (is_implicated_in)
Disease	Cryptophthalmos syndrome	FREM2 FRAS1	1.42e-04	3	204	2	C0265233
Disease	protocadherin beta-10 measurement	ZPR1 APOE	1.42e-04	3	204	2	EFO_0801974
Disease	FRASER SYNDROME 1	FREM2 FRAS1	1.42e-04	3	204	2	C4551480
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ZPR1 SEC16A SEC16B APOE JMJD1C TYW1B HELZ2 MACF1	1.66e-04	222	204	8	EFO_0008317, EFO_0020943
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	ZPR1 SEC16A SEC16B APOE JMJD1C TYW1B HELZ2 MACF1	1.82e-04	225	204	8	EFO_0008317, EFO_0020947
Disease	depressive symptom measurement	CAAP1 ACTR5 PKHD1 DAGLA EHBP1 VWF PCLO PCDHA6 MSH5 NAALADL2 PRKAR2A	2.01e-04	426	204	11	EFO_0007006
Disease	mean platelet volume	ZBTB38 MYO5A CYP24A1 ITGA2 ITGA2B ZPR1 VWF PCDHGB7 PCDHGB5 KALRN PCDHGB3 CHD9 JMJD1C TFAP4 ZFPM2 ITPRIP SLC12A7 PCDHGC3	2.77e-04	1020	204	18	EFO_0004584
Disease	dihydrofolate reductase measurement	VWF APOE	2.83e-04	4	204	2	EFO_0801526
Disease	coronary artery disease (implicated_via_orthology)	KCNJ8 APOE	2.83e-04	4	204	2	DOID:3393 (implicated_via_orthology)
Disease	neutrophil-activating peptide 2 measurement	JMJD1C ZFPM2	2.83e-04	4	204	2	EFO_0020606
Disease	oleoyl-oleoyl-glycerol (18:1/18:1) [2] measurement	ZPR1 APOE	2.83e-04	4	204	2	EFO_0800498
Disease	congenital diaphragmatic hernia (is_implicated_in)	FREM1 ZFPM2	2.83e-04	4	204	2	DOID:3827 (is_implicated_in)
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB RMI1 ZPR1 APOE JMJD1C DNAH1 TYW1B MACF1	3.06e-04	243	204	8	EFO_0004612, EFO_0020944
Disease	cholesteryl esters to total lipids in small VLDL percentage	ZPR1 SEC16A APOE JMJD1C	3.68e-04	49	204	4	EFO_0022256
Disease	cognitive inhibition measurement	TGM6 PXDNL A2ML1 USH2A	3.98e-04	50	204	4	EFO_0007969
Disease	gestational age	ZBTB38 VWA3B COL27A1 NAALADL2 TFAP4 TGFBR3	4.09e-04	138	204	6	EFO_0005112
Disease	retinal drusen	ITGA2 VWF LARP1B UNC13C	4.30e-04	51	204	4	EFO_1001155
Disease	muscular disease (implicated_via_orthology)	ACACB FASN	4.69e-04	5	204	2	DOID:0080000 (implicated_via_orthology)
Disease	linoleoyl-linoleoyl-glycerol (18:2/18:2) [1] measurement	ZPR1 APOE	4.69e-04	5	204	2	EFO_0800510
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ACACB ZPR1 APOE JMJD1C DNAH1 TYW1B MACF1	5.06e-04	200	204	7	EFO_0004611, EFO_0020945
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF DGKZ ZFPM2	5.21e-04	23	204	3	EFO_0004286, EFO_0004791
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	ZPR1 SEC16A SEC16B APOE JMJD1C TYW1B HELZ2 MACF1	5.30e-04	264	204	8	EFO_0008317, EFO_0020944
Disease	triglyceride measurement, phospholipid measurement	ACACB ZPR1 APOE JMJD1C DNAH1 TYW1B	5.51e-04	146	204	6	EFO_0004530, EFO_0004639
Disease	complex trait	ZBTB38 FREM1 ZPR1 APOE CCDC141 ADO KIAA1755 MACF1	6.29e-04	271	204	8	EFO_0010578
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	RMI1 ZPR1 APOE JMJD1C TYW1B MACF1	6.36e-04	150	204	6	EFO_0004611, EFO_0020947
Disease	FNAITP	ITGA2 ITGA2B	7.01e-04	6	204	2	C3854603
Disease	Neonatal Alloimmune Thrombocytopenia	ITGA2 ITGA2B	7.01e-04	6	204	2	C3853779
Disease	gamma-enolase measurement	JMJD1C ZFPM2	7.01e-04	6	204	2	EFO_0021845
Disease	Colorectal Neoplasms	CALCOCO2 CYP1B1 ABCA12 PROM1 CABYR FAT1 ICAM5 CDH5	7.25e-04	277	204	8	C0009404
Disease	glycerol measurement	FAT4 PCLO NPRL3	7.53e-04	26	204	3	EFO_0010115
Disease	lung carcinoma (is_implicated_in)	CYP24A1 APOE	9.76e-04	7	204	2	DOID:3905 (is_implicated_in)
Disease	X-24870 measurement	ZPR1 APOE	9.76e-04	7	204	2	EFO_0022143
Disease	grapefruit juice consumption measurement	PCLO DCP1B	9.76e-04	7	204	2	EFO_0010094
Disease	vitamin k-dependent protein S measurement	COL27A1 AKNA	9.76e-04	7	204	2	EFO_0020850
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	ACACB MAP3K4 ZPR1 EHBP1 APOE TYW1B GPCPD1	9.85e-04	224	204	7	EFO_0004574, EFO_0008317
Disease	carcinoma (implicated_via_orthology)	ERBB2 FAT4 LRRC1 SCRIB	1.02e-03	64	204	4	DOID:305 (implicated_via_orthology)
Disease	Ciliopathies	CDH23 PKHD1 USH2A TCTN1 CCDC40	1.02e-03	110	204	5	C4277690
Disease	cholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	ACACB ZPR1 APOE JMJD1C TYW1B	1.02e-03	110	204	5	EFO_0008317, EFO_0008596, EFO_0010351
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	ACACB ZPR1 APOE JMJD1C TYW1B	1.02e-03	110	204	5	EFO_0008317, EFO_0008591, EFO_0008596
Disease	chylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement	ACACB ZPR1 APOE JMJD1C TYW1B	1.02e-03	110	204	5	EFO_0004574, EFO_0008317, EFO_0008596
Disease	1,5 anhydroglucitol measurement	MGAM SI PCDHA6	1.04e-03	29	204	3	EFO_0008009
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	ACACB MAP3K4 ZPR1 EHBP1 APOE TYW1B GPCPD1	1.12e-03	229	204	7	EFO_0004639, EFO_0008317
Disease	factor XI measurement, venous thromboembolism	VWF DGKZ ZFPM2	1.15e-03	30	204	3	EFO_0004286, EFO_0004694
Disease	immature platelet fraction	VWF KALRN JMJD1C ZFPM2 SLC12A7	1.20e-03	114	204	5	EFO_0009187
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	ZPR1 APOE JMJD1C MACF1	1.21e-03	67	204	4	EFO_0008595, EFO_0020946
Disease	electrocardiography	OBSCN PROM1 PTPN3 HMCN2 MYO18B CCDC141 JMJD1C ZFPM2 NPRL3 KIAA1755 CDH17	1.23e-03	530	204	11	EFO_0004327
Disease	cholesteryl esters to total lipids in large LDL percentage	ZPR1 APOE JMJD1C	1.27e-03	31	204	3	EFO_0022249
Disease	Colorectal Carcinoma	CALCOCO2 CYP1B1 ABCA12 OBSCN PROM1 CABYR FAT1 PKHD1 KALRN CUBN AKAP9 ICAM5 CDH5	1.28e-03	702	204	13	C0009402
Disease	Benign Neoplasm	BIRC6 FASN BRCA1 OCLN	1.28e-03	68	204	4	C0086692
Disease	Neoplasms	BIRC6 FASN BRCA1 OCLN	1.28e-03	68	204	4	C0027651
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	ZPR1 APOE	1.30e-03	8	204	2	EFO_0008317, EFO_0008589, EFO_0008596
Disease	benign neoplasm (implicated_via_orthology)	LRRC1 SCRIB	1.30e-03	8	204	2	DOID:0060072 (implicated_via_orthology)
Disease	Dickkopf-related protein 4 measurement	JMJD1C ZFPM2	1.30e-03	8	204	2	EFO_0008110
Disease	omega-3 polyunsaturated fatty acid measurement	ZPR1 DAGLA APOE JMJD1C TYW1B	1.40e-03	118	204	5	EFO_0010119
Disease	immature platelet measurement	VWF KALRN JMJD1C ZFPM2 SLC12A7	1.45e-03	119	204	5	EFO_0803541
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGB7 PCDHGB5 PCDHGB3 PCDHGC3	1.50e-03	71	204	4	EFO_0007878, EFO_0007979
Disease	platelet measurement	GLB1L ITGA2B VWF KALRN CHD9 JMJD1C ZFPM2 SLC12A7	1.65e-03	315	204	8	EFO_0005036
Disease	DCN1-like protein 5 measurement	ZPR1 APOE	1.66e-03	9	204	2	EFO_0801520
Disease	diacylglycerol 36:4 measurement	ZPR1 APOE	1.66e-03	9	204	2	EFO_0020063
Disease	vascular endothelial growth factor A, isoform 121 measurement	JMJD1C ZFPM2	1.66e-03	9	204	2	EFO_0020847
Disease	22q11 partial monosomy syndrome	JMJD1C SEC24C	1.66e-03	9	204	2	C3266101
Disease	glucose metabolism decline measurement, cingulate cortex measurement	CDH23 TYW1	1.66e-03	9	204	2	EFO_0007738, EFO_0009392
Disease	factor VIII measurement, venous thromboembolism	VWF DGKZ ZFPM2	1.66e-03	34	204	3	EFO_0004286, EFO_0004630
Disease	puberty onset measurement	BIRC6 RMI1 SEC16B JMJD1C TFAP4	1.80e-03	125	204	5	EFO_0005677
Disease	Kartagener Syndrome	CCNO CCDC40 DNAH1	1.81e-03	35	204	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	CCNO CCDC40 DNAH1	1.81e-03	35	204	3	C4551906
Disease	Polynesian Bronchiectasis	CCNO CCDC40 DNAH1	1.81e-03	35	204	3	C4317124
Disease	response to alcohol	WWC2 PKHD1 LAMA2 NAALADL2	1.84e-03	75	204	4	EFO_0005526
Disease	alkaline phosphatase measurement	CALCOCO2 ACACB CYP24A1 ITPKB PRR14 KIF17 GOLGB1 SEC16B LARP1B APOE JMJD1C TFAP4 PPL TTC7A MACF1 UNC13C	1.94e-03	1015	204	16	EFO_0004533
Disease	Primary ciliary dyskinesia	CCNO CCDC40 DNAH1	1.97e-03	36	204	3	cv:C0008780
Disease	Malignant Neoplasms	ERBB2 BIRC6 FASN BRCA1 OCLN	2.00e-03	128	204	5	C0006826
Disease	1,7-dimethylurate measurement	ITGA2 NAALADL2	2.06e-03	10	204	2	EFO_0021512
Disease	estrogen measurement	SLC22A25 DAGLA	2.06e-03	10	204	2	EFO_0011007
Disease	Asymmetric crying face association	JMJD1C SEC24C	2.06e-03	10	204	2	C0431406
Disease	CXCL5 measurement	JMJD1C ZFPM2	2.06e-03	10	204	2	EFO_0009422
Disease	C-X-C motif chemokine 5 measurement	JMJD1C ZFPM2	2.06e-03	10	204	2	EFO_0008058
Disease	quinone oxidoreductase-like protein 1 measurement	ZPR1 APOE	2.06e-03	10	204	2	EFO_0021880
Disease	oleoyl-linoleoyl-glycerol (18:1/18:2) [2] measurement	ZPR1 APOE	2.06e-03	10	204	2	EFO_0800333
Disease	22q11 Deletion Syndrome	JMJD1C SEC24C	2.06e-03	10	204	2	C2936346
Disease	PR interval	ABCA12 OBSCN FREM2 FAT1 KALRN TFAP4 ZFPM2 KIAA1755 MACF1 SLC12A7	2.47e-03	495	204	10	EFO_0004462
Disease	degree of unsaturation measurement	ZPR1 APOE JMJD1C	2.48e-03	39	204	3	EFO_0022261
Disease	cytochrome p450 3a4 measurement	ZPR1 APOE	2.51e-03	11	204	2	EFO_0020303
Disease	coagulation factor XA measurement	COL27A1 AKNA	2.51e-03	11	204	2	EFO_0020266
Disease	Pancreatic Ductal Adenocarcinoma	ACACB ABCA12	2.51e-03	11	204	2	C1335302
Disease	kidney cancer (implicated_via_orthology)	LRRC1 SCRIB	2.51e-03	11	204	2	DOID:263 (implicated_via_orthology)
Disease	oleoyl-linoleoyl-glycerol (18:1/18:2) [1] measurement	ZPR1 APOE	2.51e-03	11	204	2	EFO_0800332

Protein segments in the cluster

Peptide	Gene	Start	Entry
EIEPFPEERENFLQQ	ARID4B	301	Q4LE39
PLQPEQLQVFETLEE	ERBB2	391	P04626
EQQLKVVPRFQPISE	AKAP9	2091	Q99996
RANVNLDVPLQVDFP	APBB2	566	Q92870
EQAVETEPEPELRQQ	APOE	21	P02649
DVQTPLIIQPEQRNV	BIRC6	806	Q9NR09
PAQPVAQLDLQTFRD	CCNO	86	P22674
LEDQEENPLPAALVQ	PGLS	216	O95336
EPALNPLANRQQITE	ACTRT3	106	Q9BYD9
QQFEPPLQPREREAV	ADO	151	Q96SZ5
IPIPDNRAEIISQVF	ABCA12	586	Q86UK0
FPVQQVEFISNPEVR	ARHGEF5	1561	Q12774
SQINPDLVREFPDVL	GCLM	56	P48507
VEITLQDINDNPPVF	FAT4	1726	Q6V0I7
ISIRPIPEENFLAAQ	A4GNT	171	Q9UNA3
VNRLVFQQDTLPNVP	A2ML1	1281	A8K2U0
PDTFRDQLQELCIPQ	COMMD5	106	Q9GZQ3
QLPEQIVIPFTDQVA	CABYR	311	O75952
SPFDRNVPVNLELQE	ACTR5	96	Q9H9F9
PEDVQPSAQQLELLE	CAAP1	326	Q9H8G2
LQNAETQTEREVPEP	AMBRA1	1111	Q9C0C7
EDPQERPPFQQIRLT	NPR1	786	P16066
ITDQPPLVQAIFSRD	ANKRD52	6	Q8NB46
QPLRIQAQDPEFSDL	CDHR5	381	Q9HBB8
INITDVDEPPIFQQP	CDH5	361	P33151
DINDSRPEFLNPIQT	CDH23	2166	Q9H251
LDRDVPANVLLTNPQ	ATP10A	1141	O60312
LQATVQEVQPRAEEP	AIRE	341	O43918
PVSPCQNILRVIEEF	MROH7	671	Q68CQ1
QLENQPSEFRRIESP	RAE1	196	P78406
PSLTQQQFEELVRPF	RAVER1	141	Q8IY67
LTQPIEFVPEDEIQR	RBM41	271	Q96IZ5
PDNPLTDRQIDQFLV	MTA2	181	O94776
LLFPRENATVPENEE	ITPRIP	21	Q8IWB1
VQELPLTSPVDDFRQ	OCLN	351	Q16625
PQSLRPNSEEVDEVF	NUDT8	126	Q8WV74
RVRFFIPDPNTLQQE	PTPN3	106	P26045
AQIRILVIDANDNPP	PCDHGB7	226	Q9Y5F8
INDNPPLFPVEEQRV	PCDHA6	126	Q9UN73
ESRFQVQTVLQFVPP	KIAA1549	1041	Q9HCM3
RLAEQQPQPQFIPVD	MORC1	561	Q86VD1
EDFPILFRQVQSEIP	ACACB	471	O00763
QPNIFEILQERQPDL	HECW2	1091	Q9P2P5
QQLEESRIPDQDTIP	NRG3	511	P56975
VIVSVLDINDNPPVF	FAT1	3216	Q14517
DQQLPVFQVTAPRLA	FRAS1	1591	Q86XX4
LDIPVDNPIESNNIF	KCNJ8	246	Q15842
QFSLPVAEPALREQQ	HDAC4	56	P56524
VEPGQRQPSEQELLF	HDAC4	576	P56524
PIPRISQAEEEDQQL	HINT2	96	Q9BX68
EAVQQLQPPEDGLFL	MATK	131	P42679
VQPVQPEEVSARDFL	LYSMD2	166	Q8IV50
ITSPEFVDDRPQVVN	KIAA1755	181	Q5JYT7
ADRNFTLQVQVPPVL	HMCN2	3401	Q8NDA2
ILVLQSAPVFQVEPQ	HMCN2	4296	Q8NDA2
VESVLNRVPQPEYRQ	PHKA1	1111	P46020
PVVNELERINCIPDQ	MGAM	91	O43451
FVDPVLNQLQRPPQE	JMJD1C	996	Q15652
RQFFPIVIIPTNDEQ	FREM2	1176	Q5SZK8
QRPPLVQQRFLDVAN	ZFPM2	751	Q8WW38
PIAPIIRNILNEIFQ	FSIP2	1776	Q5CZC0
DQVFPIAREEAPINL	PCLO	2841	Q9Y6V0
VRVSIEDVNDNPPKF	FAT2	2056	Q9NYQ8
VVNVSDINDNPPEFR	FAT2	2366	Q9NYQ8
QLVDIREPETQPVCF	ICAM5	86	Q9UMF0
LENLRFPNNVEPVTN	IPO7	801	O95373
QFEEQPVENLFPELT	KPTN	181	Q9Y664
VPDPVLEESFQQLQR	PPL	941	O60437
LEEFRQTQQVPPNKI	NAA16	171	Q6N069
EFRNPLAPAVQETQL	NPRL3	376	Q12980
FNITILPVDNQVPEA	FREM1	766	Q5H8C1
LNPNFIQEVAPEFLV	KALRN	2461	O60229
PQERPAVNQTVAEVI	KREMEN1	326	Q96MU8
RIRVAPQQDDLDSPQ	LAMA2	551	P24043
IPPDNLSIQEFQRNE	MON2	1506	Q7Z3U7
TELRIQVTDANDNPP	PCDHGB5	226	Q9Y5G0
TQIRVIVADANDNPP	PCDHGB3	226	Q9Y5G1
TIVRVQVSDINDNPP	PCDHGC3	441	Q9UN70
FQVEIEVLDINDNPP	PCDH10	106	Q9P2E7
PPAIQEEVLAQQRAE	HUWE1	3026	Q7Z6Z7
LDVRQIPAAQEQPFI	ITGA2	801	P17301
QVVDERVLVFNPEEP	KIF18B	31	Q86Y91
QRPTPEELEQRNILQ	PHACTR4	591	Q8IZ21
TEFLDPFQRVIQPEE	PLPP4	21	Q5VZY2
LSDNEIQRLPPEIAN	LRRC1	66	Q9BTT6
LIQRDQEPIPQNIDR	MACF1	6901	Q9UPN3
RVLDVNDNPPVFSQD	DCHS2	2436	Q6V1P9
AENLEAQPQSTVRPE	PPIG	261	Q13427
EQQEARAESPLPQVS	OBSCN	7236	Q5VST9
PEEVLQRVNVQPELV	RABGGTB	316	P53611
PQVPQQTTVLDLRFN	PXDNL	46	A1KZ92
FVTEPQIIQERPLTN	BRCA1	486	P38398
LEEQNRQEPLIPVEQ	BTBD19	236	C9JJ37
LAAPPETRIQLQFED	CUBN	2251	O60494
EQQTPLFQVISPQRI	DCP1B	501	Q8IZD4
TNLEPRFIEPQTANL	DNAH1	3646	Q9P2D7
NQFIRPVENVSDPVT	CHRNA6	46	Q15825
LVDPNIFIQPITEER	CHD9	1906	Q3L8U1
VVDQPDLDPQFVREF	CDHR2	231	Q9BYE9
LESIFNAPDIQRQLP	DNAH6	1111	Q9C0G6
EPVEFRCILEAQNVP	IGSF3	296	O75054
PEQPNIFQVEQLERL	GPCPD1	616	Q9NPB8
NKFIAPSVPQQEERI	CCDC141	1056	Q6ZP82
NVQRINVRDVSPFPV	DOCK9	1176	Q9BZ29
IQSVLPENQVPRAED	CYP24A1	356	Q07973
SIFRTPLQLDPQQEQ	GAS2L1	501	Q99501
RITFTEPNIQNVPRD	POLQ	2241	O75417
PREGDLPVFQDQIQQ	CCDC40	236	Q4G0X9
ELEDVPLQPQVQFLD	GLB1L	606	Q6UWU2
ITRVPQEFQTPEQAT	AKNA	426	Q7Z591
IPFQFRPENEEDILV	CALCOCO2	121	Q13137
RTQDPQQLPIISVDN	COL27A1	1826	Q8IZC6
PNNLVNPVQELETER	EHBP1	381	Q8NDI1
QSADLIQFEERPQEP	MARF1	1646	Q9Y4F3
QEILLRAQFEPNLVP	DAGLA	956	Q9Y4D2
VLRQQPPDLVEFAVE	PRKAR2A	21	P13861
QPQQTLATEPRENVI	CDH12	26	P55289
PNPVRTVFREFEQLN	CYP1B1	251	Q16678
PENLDFIEVNVSLPR	SERPINB1	261	P30740
DQQPVPEQLRIQVSR	DGKZ	636	Q13574
LVDSFLQQDPAQPVV	FKRP	66	Q9H9S5
PEARLVLEVQFQIDP	HELZ2	461	Q9BYK8
SAPRRQQEQQVPILE	FASN	1101	P49327
PSPVTVFEVQENERL	CDH17	341	Q12864
PETRNQPLLDSIQDV	SLC22A25	516	Q6T423
IPSPIQVIEDDRNNR	SEC24C	326	P53992
PRENSPFLNNVEVEQ	SLC12A7	46	Q9Y666
DQPQEESEEQPVFRL	SAAL1	231	Q96ER3
QQPPEDRTQDVLAQD	CEP131	421	Q9UPN4
QPLVPQLLVQVRIDF	NEURL4	1166	Q96JN8
ENLTPELPFEPNQEV	LARP1B	526	Q659C4
APQQILIATFDEPRT	PANX2	656	Q96RD6
DPLPVVDQQQVLARL	KIF17	731	Q9P2E2
DARRNVPQNDPVTVV	MNDA	201	P41218
NRFTVLPNIDPEIDE	MSH5	391	O43196
VPEIRQPIDNSFDIQ	MAP3K4	471	Q9Y6R4
EEPESLRVNAQVFLP	NRK	576	Q7Z2Y5
IIQFFSPQPTEIRIQ	USH2A	386	O75445
QLDREQFNPDVITFP	DROSHA	756	Q9NRR4
DLEPNEVRLEQQSVP	XAB2	831	Q9HCS7
DFSNPSDIPDQVIRV	RAPGEF6	741	Q8TEU7
RVGVPFNIPLEFQDE	SMCHD1	836	A6NHR9
NLPPREDIINVLQET	PRUNE2	201	Q8WUY3
IPNNSNENIPRVTDV	RMI1	221	Q9H9A7
LQRLPQAEPVEIVAF	SMIM5	21	Q71RC9
EPRFVEVLLQNNTPS	SAMD9L	286	Q8IVG5
LQPPEALVERQGQFL	ITPKB	336	P27987
PERNFVLPEEIIQEV	MRGBP	101	Q9NV56
IDETPNFIIPAQRAE	PRR14	171	Q9BWN1
PPVDAELDNVNNVLR	PROM1	336	O43490
DQLPAFIQIDLQENP	SLITRK2	516	Q9H156
EVLLQPNPSARVEEF	SH3GLB2	61	Q9NR46
EIEIQPRVVPNASFF	NAP1L3	426	Q99457
PQTQQVDLDLSRPLF	ORC6	126	Q9Y5N6
QLEEVPSALPRNLEQ	PRELP	161	P51888
REITNQVVPQERQPE	RNF216	186	Q9NWF9
QVVPQERQPEAELGR	RNF216	191	Q9NWF9
EPVLDPQQIQAFDQL	VPS8	1356	Q8N3P4
RVIVQSFPEEPSQVQ	PKHD1	2186	P08F94
NELPVQPQLVFLDEQ	PKHD1	3756	P08F94
VNVRINCIPEQFPTE	SI	71	P14410
LSDNEIQRLPPEVAN	SCRIB	66	Q14160
QIFLPEPEQPSRLQD	ITGA2B	891	P08514
EVPRVLVNLVDFLNP	PLB1	891	Q6P1J6
QEEPQLSPENEARLP	TFCP2L1	31	Q9NZI6
FIPTVREVQCPEANI	AHNAK2	5406	Q8IVF2
LIFNSFLPVNQPEEV	NCAPG2	521	Q86XI2
ATIPRQDEVPQQTVA	TNFRSF10D	56	Q9UBN6
REQPSDPQAEQELIN	VPS50	41	Q96JG6
LEAPVTEPRFLEQLQ	VPS52	186	Q8N1B4
LFRPISAEDEEQQPT	ZPR1	31	O75312
QLPTDPIEEQFPVLN	ZMYND19	131	Q96E35
VFQPNQPLVDSIDLD	WWC2	841	Q6AWC2
PPQQRPRLQEETEAA	TSPYL2	41	Q9H2G4
VFPSNTQPFQRLLEE	WDFY3	736	Q8IZQ1
EIREDENQNIPEQPV	UNC13C	946	Q8NB66
NAPILIQDFETLPRE	VWF	1646	P04275
NLEFVQNQEVLPSEP	SEC16A	461	O15027
IDPRANPTQLNTVEF	TFCP2	161	Q12800
ETVRELLENPVQPIN	TLN1	1371	Q9Y490
QPATENQRVPLIVAA	ARHGAP23	911	Q9P227
EIRDLYVNIQPVQEP	RTCA	221	O00442
ELPQDFLRITPTQQQ	TOLLIP	16	Q9H0E2
FTANPPQRVFELVDQ	TCTN1	131	Q2MV58
PQRVFELVDQINPSI	TCTN1	136	Q2MV58
FINATLPPQERITAQ	TRABD2A	276	Q86V40
NLPENFRRPQTDQAV	SMAP1	101	Q8IYB5
SEFLPPEVNQLLQDV	ZNF518A	776	Q6AHZ1
QALISPRETENNPFE	nan	86	Q6ZUG5
ETLRPSVPEIFNNIQ	PLCH1	1411	Q4KWH8
TFQDDFVPQEIKPRQ	SAXO2	116	Q658L1
RQPPVANLINLTDED	SEC16B	401	Q96JE7
VAVVDQNPSQVRLPA	MYO18B	1011	Q8IUG5
PFKQDVSPIERNEQL	ZNF226	51	Q9NYT6
ARPLDQVLVIDSPNN	ZCCHC18	301	P0CG32
LERAQQLAPSDPQVI	TTC7A	521	Q9ULT0
VRPINAEPVFQAQEI	TASOR2	1671	Q5VWN6
EVNQERSPQPAAVLT	ZBTB38	291	Q8NAP3
VTNAQFPAEIRNLEP	TYW1	511	Q9NV66
DQPPETVIDQVKRFQ	VWA3B	611	Q502W6
QRPNDPETVETILNL	RPTN	46	Q6XPR3
QLFVLQPSRVQPESQ	SLC18A2	266	Q05940
ENIFQTQPLNPILED	EDA2R	206	Q9HAV5
IDENPELFQLRPAQN	PC	481	P11498
LANIPLTPETQRDQE	TFAP4	31	Q01664
PEFQLPVTEPDINNR	SAMD4A	681	Q9UPU9
DVPTLEPQERASVQF	TGM6	656	O95932
PEPQQDEILQRLLFS	TEX46	51	H3BTG2
QFPAEIRNLEPVTQL	TYW1B	451	Q6NUM6
ENPIFVVSREPLNTI	TBK1	376	Q9UHD2
SIQLFPGLREPEEVQ	TGFBR3	431	Q03167
PEELREPQQSFSEAQ	GOLGB1	3126	Q14789
QQQELSRFLNPPSIE	NALCN	1601	Q8IZF0
EVILQIANEPVLPFN	NAALADL2	636	Q58DX5
AQNLQLPPEARIEAS	MYO5A	1386	Q9Y4I1