Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 FZD10 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	9.21e-23	884	133	40	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	5.36e-20	431	133	28	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CHRNA3 CHRNA4 CCKAR CHRNB4 OR8B3 OR8B8 ZACN OR2A12 OR13C9 OR10H3 OR13C2 FZD10 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.73e-19	1353	133	44	GO:0004888
GeneOntologyMolecularFunction	transporter activity	SLC37A1 ABCC1 SLC29A3 SLC22A25 SLC6A17 OCA2 STING1 ANO10 SLC7A7 SLC30A4 ABCA8 CHRNA3 CHRNA4 SLC22A12 ATP10D CHRNB4 SLC7A9 SLC22A9 ZACN ATP11B SLCO4C1 SLC44A5 SLC41A3 ABCA6 SERINC3 ATP11C CACNA1I SLC35E4 SLC45A1 ATP4A SLC4A11	2.78e-10	1289	133	31	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC37A1 ABCC1 SLC29A3 SLC22A25 SLC6A17 OCA2 STING1 ANO10 SLC7A7 SLC30A4 ABCA8 CHRNA3 CHRNA4 SLC22A12 CHRNB4 SLC7A9 SLC22A9 ZACN ATP11B SLCO4C1 SLC44A5 SLC41A3 ABCA6 SERINC3 CACNA1I SLC35E4 SLC45A1 ATP4A SLC4A11	7.18e-10	1180	133	29	GO:0022857
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC37A1 ABCC1 SLC29A3 SLC22A25 SLC6A17 SLC30A4 ABCA8 SLC7A9 SLC22A9 SLCO4C1 SLC44A5 SLC41A3 ABCA6 SLC35E4 SLC45A1 ATP4A SLC4A11	1.95e-08	477	133	17	GO:0022804
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC37A1 SLC22A25 SLC6A17 SLC30A4 SLC7A9 SLC22A9 SLCO4C1 SLC44A5 SLC41A3 SLC35E4 SLC45A1 SLC4A11	7.01e-07	296	133	12	GO:0015291
GeneOntologyMolecularFunction	odorant binding	OR5AU1 OR8K3 OR10T2 OR8B3 OR8B8 OR8D4 OR8B2 OR5D13	2.16e-06	127	133	8	GO:0005549
GeneOntologyMolecularFunction	lipid transporter activity	ABCC1 SLC22A25 ANO10 ABCA8 ATP10D SLC22A9 ATP11B ABCA6 ATP11C	6.72e-06	196	133	9	GO:0005319
GeneOntologyMolecularFunction	antiporter activity	SLC37A1 SLC30A4 SLC7A9 SLC44A5 SLC41A3 SLC35E4 SLC4A11	3.90e-05	138	133	7	GO:0015297
GeneOntologyMolecularFunction	acetylcholine binding	CHRNA3 CHRNA4 CHRNB4	7.87e-05	13	133	3	GO:0042166
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC37A1 ABCC1 SLC22A25 SLC7A7 SLC7A9 SLC22A9 SLCO4C1 SERINC3 SLC4A11	1.55e-04	293	133	9	GO:0008514
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA3 CHRNA4 CHRNB4	1.83e-04	17	133	3	GO:0022848
GeneOntologyMolecularFunction	flippase activity	ATP10D ATP11B ATP11C	1.83e-04	17	133	3	GO:0140327
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLC22A25 SLC22A9 SLCO4C1	2.19e-04	18	133	3	GO:0015347
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ANO10 ATP10D ATP11B ATP11C	3.69e-04	51	133	4	GO:0140303
GeneOntologyMolecularFunction	short-chain fatty acid transmembrane transporter activity	SLC22A25 SLC22A9	4.35e-04	5	133	2	GO:0015636
GeneOntologyMolecularFunction	prostaglandin E receptor activity	PTGER2 PTGER4	4.35e-04	5	133	2	GO:0004957
GeneOntologyMolecularFunction	fatty acid transmembrane transporter activity	ABCC1 SLC22A25 SLC22A9	4.64e-04	23	133	3	GO:0015245
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA3 CHRNA4 CHRNB4	4.64e-04	23	133	3	GO:0015464
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	OCA2 STING1 ANO10 SLC30A4 CHRNA3 CHRNA4 CHRNB4 ZACN ATP11B SLC41A3 CACNA1I SLC45A1 ATP4A SLC4A11	8.37e-04	793	133	14	GO:0015075
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP10D ATP11B ATP11C	8.38e-04	28	133	3	GO:0140326
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ATP11B ATP11C	9.05e-04	7	133	2	GO:0090555
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ATP11B ATP11C	1.54e-03	9	133	2	GO:0090556
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	STING1 ANO10 SLC30A4 CHRNA3 CHRNA4 CHRNB4 ZACN SLC41A3 CACNA1I SLC45A1 ATP4A SLC4A11	1.63e-03	664	133	12	GO:0008324
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRNA3 CHRNA4 CHRNB4 ZACN	1.75e-03	77	133	4	GO:0005230
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	NPY2R F2RL3 MLNR GPR84 CCKAR	1.98e-03	133	133	5	GO:0008528
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCC1 RHOD ABCA8 ATP10D DNAH12 MDN1 ATP11B ABCA6 ATP11C ATP4A RAC1 RAC2 RAC3	2.02e-03	775	133	13	GO:0017111
GeneOntologyMolecularFunction	monoatomic cation channel activity	STING1 ANO10 CHRNA3 CHRNA4 CHRNB4 ZACN CACNA1I SLC4A11	2.13e-03	343	133	8	GO:0005261
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC29A3 SLC7A7 SLC44A5 SERINC3	2.30e-03	83	133	4	GO:0015101
GeneOntologyMolecularFunction	prostaglandin receptor activity	PTGER2 PTGER4	2.33e-03	11	133	2	GO:0004955
GeneOntologyMolecularFunction	peptide receptor activity	NPY2R F2RL3 MLNR GPR84 CCKAR	2.47e-03	140	133	5	GO:0001653
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	ANO10 CHRNA3 CHRNA4 CHRNB4 ZACN	2.47e-03	140	133	5	GO:0099094
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC1 SLC22A25 SLC7A7 SLC7A9 SLC22A9 SERINC3	2.66e-03	207	133	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC1 SLC22A25 SLC7A7 SLC7A9 SLC22A9 SERINC3	2.73e-03	208	133	6	GO:0005342
GeneOntologyMolecularFunction	toxin transmembrane transporter activity	SLC22A25 SLC22A9	2.78e-03	12	133	2	GO:0019534
GeneOntologyMolecularFunction	prostanoid receptor activity	PTGER2 PTGER4	2.78e-03	12	133	2	GO:0004954
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC1 ABCA8 ATP10D DNAH12 MDN1 ATP11B ABCA6 ATP11C ATP4A	2.82e-03	441	133	9	GO:0016887
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	CHRNA3 CHRNA4 CHRNB4	2.93e-03	43	133	3	GO:0005231
GeneOntologyMolecularFunction	monoatomic ion channel activity	OCA2 STING1 ANO10 CHRNA3 CHRNA4 CHRNB4 ZACN CACNA1I SLC4A11	3.66e-03	459	133	9	GO:0005216
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP11B ATP11C	3.80e-03	14	133	2	GO:0140333
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCC1 RHOD ABCA8 ATP10D DNAH12 MDN1 ATP11B ABCA6 ATP11C ATP4A RAC1 RAC2 RAC3	3.99e-03	839	133	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCC1 RHOD ABCA8 ATP10D DNAH12 MDN1 ATP11B ABCA6 ATP11C ATP4A RAC1 RAC2 RAC3	4.03e-03	840	133	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCC1 RHOD ABCA8 ATP10D DNAH12 MDN1 ATP11B ABCA6 ATP11C ATP4A RAC1 RAC2 RAC3	4.03e-03	840	133	13	GO:0016818
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC1 ABCA8 ABCA6	4.26e-03	49	133	3	GO:0140359
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC1 ABCA8	4.37e-03	15	133	2	GO:0008559
GeneOntologyMolecularFunction	neurotransmitter receptor activity	HTR1D CHRNA3 CHRNA4 CHRNB4	4.50e-03	100	133	4	GO:0030594
GeneOntologyMolecularFunction	floppase activity	ATP11B ATP11C	4.97e-03	16	133	2	GO:0140328
GeneOntologyMolecularFunction	icosanoid receptor activity	PTGER2 PTGER4	4.97e-03	16	133	2	GO:0004953
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC37A1 ABCC1 OCA2 ANO10 SLC4A11	5.79e-03	171	133	5	GO:0015103
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC1 ABCA8 ABCA6 ATP4A	6.11e-03	109	133	4	GO:0042626
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNA3 CHRNA4 CHRNB4	6.50e-03	57	133	3	GO:1904315
GeneOntologyBiologicalProcess	sensory perception of smell	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 NXNL2 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.37e-20	465	133	29	GO:0007608
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 FZD10 OR4D5 OR8D4 OR8B2 NOS2 PIK3R5 RAC1 RAC2 HTT OR5D13 OR1L4	2.27e-20	1395	133	45	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	2.46e-20	432	133	28	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 NXNL2 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.04e-19	547	133	30	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	5.32e-19	485	133	28	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	4.05e-18	524	133	28	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	6.15e-17	582	133	28	GO:0050906
GeneOntologyBiologicalProcess	sensory perception	USP53 OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 NXNL2 OR2B6 OR10T2 OR10X1 CHRNA4 OR8B3 OR8B8 CRYAA OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 USH2A OR5D13 OR1L4	4.92e-15	1072	133	34	GO:0007600
GeneOntologyBiologicalProcess	detection of stimulus	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.44e-14	722	133	28	GO:0051606
GeneOntologyBiologicalProcess	monoatomic ion transport	ABCC1 SLC22A25 ZMPSTE24 F2RL3 SLC6A17 OCA2 STING1 ANO10 SLC30A4 CHRNA3 CHRNA4 SLC22A12 ATP10D CCKAR CHRNB4 SLC22A9 ZACN ATP11B SLCO4C1 SLC41A3 ATP11C CACNA1I ATP4A SLC4A11 HTT	2.10e-06	1374	133	25	GO:0006811
GeneOntologyBiologicalProcess	behavioral response to nicotine	CHRNA3 CHRNA4 CHRNB4	4.16e-05	11	133	3	GO:0035095
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	ABCC1 F2RL3 SLC6A17 OCA2 STING1 ANO10 SLC30A4 CHRNA3 CHRNA4 ATP10D CHRNB4 ZACN ATP11B SLC41A3 ATP11C CACNA1I ATP4A SLC4A11 HTT	9.84e-05	1115	133	19	GO:0034220
GeneOntologyBiologicalProcess	synaptic transmission involved in micturition	CHRNA3 CHRNB4	1.23e-04	3	133	2	GO:0060084
GeneOntologyBiologicalProcess	organic anion transport	SLC37A1 ABCC1 SLC22A25 SLC6A17 SLC7A7 SLC22A12 SLC7A9 SLC22A9 SLCO4C1 SERINC3 NOS2 SLC4A11	1.28e-04	515	133	12	GO:0015711
GeneOntologyCellularComponent	NADPH oxidase complex	DUOX1 RAC1 RAC2 RAC3	5.03e-06	18	137	4	GO:0043020
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP10D ATP11B ATP11C	9.51e-05	14	137	3	GO:1990531
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNA3 CHRNA4 CHRNB4	2.09e-04	18	137	3	GO:0005892
GeneOntologyCellularComponent	endoplasmic reticulum membrane	PIGY SLC37A1 ZMPSTE24 OR2M2 OCA2 OR2M3 STING1 ATP10D STT3A TMEM33 ZDHHC22 DISP3 CYP7B1 ATP11C UGT2B28 UBIAD1 ALG6 RAC1 RAC2 RAC3	2.93e-04	1293	137	20	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	PIGY SLC37A1 ZMPSTE24 OR2M2 OCA2 OR2M3 STING1 ATP10D STT3A TMEM33 ZDHHC22 DISP3 CYP7B1 ATP11C UGT2B28 UBIAD1 ALG6 RAC1 RAC2 RAC3	3.11e-04	1299	137	20	GO:0098827
GeneOntologyCellularComponent	cholinergic synapse	CHRNA3 CHRNA4 CHRNB4	3.87e-04	22	137	3	GO:0098981
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	PIGY SLC37A1 ZMPSTE24 OR2M2 OCA2 OR2M3 STING1 ATP10D STT3A TMEM33 ZDHHC22 DISP3 CYP7B1 ATP11C UGT2B28 UBIAD1 ALG6 RAC1 RAC2 RAC3	4.10e-04	1327	137	20	GO:0042175
GeneOntologyCellularComponent	transporter complex	CHRNA3 CHRNA4 ATP10D CHRNB4 WDR93 ZACN ATP11B CNTNAP2 ATP11C CACNA1I ATP4A	1.01e-03	550	137	11	GO:1990351
Domain	GPCR_Rhodpsn_7TM	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	5.65e-25	670	134	39	IPR017452
Domain	7tm_1	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	8.28e-25	677	134	39	PF00001
Domain	G_PROTEIN_RECEP_F1_1	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.27e-24	685	134	39	PS00237
Domain	G_PROTEIN_RECEP_F1_2	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.75e-24	691	134	39	PS50262
Domain	GPCR_Rhodpsn	NPY2R HTR1D OR2L3 OR2M2 OR2B2 GPR33 OR5AU1 F2RL3 OR13C5 MLNR OR13C8 OR13C4 OR2G2 OXGR1 GPR84 OR2J3 OR10H4 OR2B3 TAAR5 OR6C68 OR8K3 OR2M3 PTGER2 OR2B6 PTGER4 OR10T2 OR10X1 CCKAR OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.85e-24	692	134	39	IPR000276
Domain	Olfact_rcpt	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	3.19e-20	393	134	28	IPR000725
Domain	RHO	RHOD RAC1 RAC2 RAC3	1.12e-05	20	134	4	PS51420
Domain	7TM_GPCR_Srsx	NPY2R HTR1D OR2M2 MLNR TAAR5 OR2M3 CCKAR	1.62e-05	112	134	7	SM01381
Domain	-	CHRNA3 CHRNA4 CHRNB4 ZACN	2.02e-05	23	134	4	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRNA3 CHRNA4 CHRNB4 ZACN	2.02e-05	23	134	4	IPR027361
Domain	-	ATP10D ATP11B ATP11C ATP4A	7.79e-05	32	134	4	3.40.1110.10
Domain	-	ATP10D ATP11B ATP11C ATP4A	7.79e-05	32	134	4	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP10D ATP11B ATP11C ATP4A	1.12e-04	35	134	4	IPR023299
Domain	P_typ_ATPase_c	ATP10D ATP11B ATP11C	1.24e-04	14	134	3	IPR032630
Domain	P-type_ATPase_N	ATP10D ATP11B ATP11C	1.24e-04	14	134	3	IPR032631
Domain	P-type_ATPase_IV	ATP10D ATP11B ATP11C	1.24e-04	14	134	3	IPR006539
Domain	PhoLip_ATPase_C	ATP10D ATP11B ATP11C	1.24e-04	14	134	3	PF16212
Domain	PhoLip_ATPase_N	ATP10D ATP11B ATP11C	1.24e-04	14	134	3	PF16209
Domain	P_typ_ATPase	ATP10D ATP11B ATP11C ATP4A	1.25e-04	36	134	4	IPR001757
Domain	ATPase_P-typ_P_site	ATP10D ATP11B ATP11C ATP4A	1.25e-04	36	134	4	IPR018303
Domain	ATPASE_E1_E2	ATP10D ATP11B ATP11C ATP4A	1.25e-04	36	134	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP10D ATP11B ATP11C ATP4A	1.39e-04	37	134	4	IPR008250
Domain	E1-E2_ATPase	ATP10D ATP11B ATP11C ATP4A	1.39e-04	37	134	4	PF00122
Domain	Nicotinic_acetylcholine_rcpt	CHRNA3 CHRNA4 CHRNB4	1.89e-04	16	134	3	IPR002394
Domain	MFS_1	SLC37A1 SLC22A25 SLC22A12 SLC22A9 SLC45A1	2.30e-04	77	134	5	PF07690
Domain	MFS	SLC37A1 SLC22A25 SLC22A12 SLC22A9 SLC45A1	2.30e-04	77	134	5	IPR011701
Domain	Neurotransmitter_ion_chnl_CS	CHRNA3 CHRNA4 CHRNB4 ZACN	3.00e-04	45	134	4	IPR018000
Domain	Neur_chan_LBD	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	PF02931
Domain	NEUROTR_ION_CHANNEL	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	PS00236
Domain	Neurotrans-gated_channel_TM	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	IPR006029
Domain	-	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	2.70.170.10
Domain	Neur_channel	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	IPR006201
Domain	Neur_chan_lig-bd	CHRNA3 CHRNA4 CHRNB4 ZACN	3.56e-04	47	134	4	IPR006202
Domain	MFS	SLC37A1 SLC22A25 SLC22A12 SLC22A9 SLCO4C1	1.09e-03	108	134	5	PS50850
Domain	Prostanoid_rcpt	PTGER2 PTGER4	1.39e-03	8	134	2	IPR008365
Domain	HAD-like_dom	ATP10D ATP11B ATP11C ATP4A	2.51e-03	79	134	4	IPR023214
Domain	MFS_dom	SLC37A1 SLC22A25 SLC22A12 SLC22A9 SLCO4C1	2.81e-03	134	134	5	IPR020846
Domain	ABC_A	ABCA8 ABCA6	3.22e-03	12	134	2	IPR026082
Domain	AA_permease_2	SLC7A7 SLC7A9	3.78e-03	13	134	2	PF13520
Domain	SSD	ZDHHC22 DISP3	3.78e-03	13	134	2	IPR000731
Domain	SSD	ZDHHC22 DISP3	3.78e-03	13	134	2	PS50156
Domain	AA/rel_permease1	SLC7A7 SLC7A9	3.78e-03	13	134	2	IPR002293
Domain	AAA+_ATPase	ABCC1 ABCA8 DNAH12 MDN1 ABCA6	3.83e-03	144	134	5	IPR003593
Domain	AAA	ABCC1 ABCA8 DNAH12 MDN1 ABCA6	3.83e-03	144	134	5	SM00382
Domain	F-box-like	ECT2L FBXO16 FBXO41	3.86e-03	44	134	3	PF12937
Domain	Neur_chan_memb	CHRNA3 CHRNA4 CHRNB4	4.38e-03	46	134	3	PF02932
Domain	ATPase_dyneun-rel_AAA	DNAH12 MDN1	4.39e-03	14	134	2	IPR011704
Domain	AAA_5	DNAH12 MDN1	4.39e-03	14	134	2	PF07728
Domain	ABC_tran	ABCC1 ABCA8 ABCA6	4.93e-03	48	134	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC1 ABCA8 ABCA6	4.93e-03	48	134	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCC1 ABCA8 ABCA6	5.23e-03	49	134	3	PS00211
Domain	ABC_transporter-like	ABCC1 ABCA8 ABCA6	5.53e-03	50	134	3	IPR003439
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	3.32e-19	417	107	28	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR5D13 OR1L4	8.59e-18	389	107	26	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR6C68 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.82e-14	636	107	28	M41834
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	NPY2R HTR1D OR2B2 F2RL3 MLNR OR2J3 OR2B3 PTGER2 OR2B6 PTGER4 CCKAR OR8B8 OR10H3	8.21e-08	260	107	13	M39397
Pathway	WP_GPCRS_ODORANT	GPR33 GPR84 OR10H4 TAAR5 OR2B6 OR8B3 OR8B8 OR10H3 OR8B2	2.96e-06	157	107	9	MM15872
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	NPY2R HTR1D F2RL3 MLNR TAAR5 PTGER2 PTGER4 CHRNA3 CHRNA4 CCKAR CHRNB4	6.79e-06	272	107	11	M13380
Pathway	REACTOME_HIGHLY_SODIUM_PERMEABLE_POSTSYNAPTIC_ACETYLCHOLINE_NICOTINIC_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	1.46e-05	7	107	3	M27596
Pathway	REACTOME_HIGHLY_SODIUM_PERMEABLE_POSTSYNAPTIC_ACETYLCHOLINE_NICOTINIC_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	1.46e-05	7	107	3	MM15311
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	1.46e-05	7	107	3	M47538
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	3.45e-05	9	107	3	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	3.45e-05	9	107	3	MM15313
Pathway	KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	4.91e-05	10	107	3	M47727
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	6.71e-05	11	107	3	M883
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	NPY2R HTR1D GPR33 F2RL3 PTGER2 PTGER4 CCKAR OR8B8	8.46e-05	186	107	8	MM15994
Pathway	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	8.90e-05	12	107	3	M48008
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA3 CHRNA4 CHRNB4	8.90e-05	12	107	3	MM15312
Pathway	WP_RALA_DOWNSTREAM_REGULATED_GENES	RAC1 RAC2 RAC3	8.90e-05	12	107	3	M39408
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA3 CHRNA4 CHRNB4	1.46e-04	14	107	3	M757
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA3 CHRNA4 CHRNB4	1.81e-04	15	107	3	MM14704
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2J3 OR8K3 OR10X1 OR8B3 OR8B2	1.88e-04	70	107	5	MM14984
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC1 SLC29A3 ANO10 SLC7A7 ABCA8 SLC22A12 ATP10D SLC7A9 ATP11B SLCO4C1 SLC44A5 ABCA6 ATP11C UNC79 ATP4A	1.88e-04	681	107	15	MM14985
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPY2R HTR1D F2RL3 MLNR OXGR1 TAAR5 PTGER2 PLPPR1 PTGER4 CCKAR	2.03e-04	330	107	10	M18334
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY	CHRNA3 CHRNA4 CHRNB4	3.77e-04	19	107	3	M47793
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC1 SLC29A3 ANO10 SLC7A7 ABCA8 SLC22A12 ATP10D SLC7A9 ATP11B SLCO4C1 SLC44A5 ABCA6 ATP11C UNC79 ATP4A	4.31e-04	736	107	15	M27287
Pathway	REACTOME_GPCR_LIGAND_BINDING	NPY2R HTR1D F2RL3 MLNR OXGR1 TAAR5 PTGER2 PLPPR1 PTGER4 CCKAR FZD10	7.72e-04	463	107	11	M507
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP10D ATP11B ATP11C ATP4A	7.95e-04	55	107	4	M971
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP10D ATP11B ATP11C ATP4A	9.10e-04	57	107	4	MM15643
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPY2R HTR1D F2RL3 OXGR1 TAAR5 PTGER2 PLPPR1 PTGER4 CCKAR	9.67e-04	333	107	9	MM14963
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	9.73e-04	26	107	3	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	9.73e-04	26	107	3	M47562
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	1.21e-03	28	107	3	M47655
Pathway	KEGG_COLORECTAL_CANCER	PIK3R5 RAC1 RAC2 RAC3	1.25e-03	62	107	4	M14631
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	1.49e-03	30	107	3	M47718
Pubmed	The human olfactory receptor gene family.	OR2B2 OR5AU1 OR13C5 OR13C8 OR13C4 OR2G2 OR2J3 OR10H4 OR2B3 OR8K3 OR2M3 OR2B6 OR10T2 OR10X1 OR8B3 OR8B8 OR2A12 OR13C9 OR10H3 OR13C2 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	1.42e-19	541	138	25	14983052
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C8 OR2J3 OR10H4 OR6C68 OR8K3 OR2M3 OR2B6 OR10X1 OR8B3 OR8B8 OR2A12 OR10H3 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	4.85e-19	343	138	21	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C8 OR2J3 OR10H4 OR6C68 OR8K3 OR2M3 OR2B6 OR10X1 OR8B3 OR8B8 OR2A12 OR10H3 OR4D5 OR8D4 OR8B2 OR5D13 OR1L4	5.80e-19	346	138	21	14611657
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C8 OR2J3 OR10H4 OR6C68 OR8K3 OR2M3 OR2B6 OR10X1 OR8B3 OR8B8 OR2A12 OR10H3 OR4D5 OR8D4 OR8B2 OR1L4	7.76e-18	340	138	20	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2L3 OR2M2 OR2B2 OR5AU1 OR13C8 OR2J3 OR10H4 OR6C68 OR8K3 OR2M3 OR2B6 OR10X1 OR8B3 OR8B8 OR2A12 OR10H3 OR4D5 OR8D4 OR8B2 OR1L4	7.76e-18	340	138	20	11802173
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR2M2 OR5AU1 OR13C8 OR13C4 OR2J3 OR10H4 OR2B3 OR2M3 OR10X1 OR8B8 OR2A12 OR8B2 OR1L4	5.05e-12	219	138	13	12213199
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C8 OR13C4 OR13C9 OR13C2	7.08e-10	12	138	5	12906860
Pubmed	Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.	SLC29A3 SLC22A25 SLC22A12 SLC22A9 SLCO4C1	3.86e-09	16	138	5	19679677
Pubmed	Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.	RAC1 RAC2 RAC3	6.11e-08	3	138	3	16081809
Pubmed	Signaling and cytoskeletal requirements in erythroblast enucleation.	RAC1 RAC2 RAC3	6.11e-08	3	138	3	22461493
Pubmed	rac, a novel ras-related family of proteins that are botulinum toxin substrates.	RAC1 RAC2 RAC3	6.11e-08	3	138	3	2674130
Pubmed	Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.	RAC1 RAC2 RAC3	6.11e-08	3	138	3	22123845
Pubmed	Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis.	CHRNA3 CHRNA4 CHRNB4	6.11e-08	3	138	3	19628475
Pubmed	Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What's behind Neuro-RACopathies.	RAC1 RAC2 RAC3	6.11e-08	3	138	3	34943902
Pubmed	Molecular physiology of renal organic anion transporters.	ABCC1 SLC22A25 SLC22A12 SLC22A9	1.65e-07	13	138	4	16403838
Pubmed	Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors.	CHRNA3 CHRNA4 CHRNB4	2.44e-07	4	138	3	16091357
Pubmed	Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus.	CHRNA3 CHRNA4 CHRNB4	6.08e-07	5	138	3	12663058
Pubmed	Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages.	NOS2 RAC1 RAC2	6.08e-07	5	138	3	11457725
Pubmed	Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula.	CHRNA3 CHRNA4 CHRNB4	6.08e-07	5	138	3	25031416
Pubmed	Low ethanol concentration alters CHRNA5 RNA levels during early human development.	CHRNA3 CHRNA4 CHRNB4	6.08e-07	5	138	3	20438829
Pubmed	Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study.	CHRNA3 CHRNA4 CHRNB4	6.08e-07	5	138	3	8987816
Pubmed	PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.	RAC1 RAC2 RAC3	6.08e-07	5	138	3	22043008
Pubmed	Changes in Nicotinic Neurotransmission during Enteric Nervous System Development.	CHRNA3 CHRNA4 CHRNB4	1.21e-06	6	138	3	25948261
Pubmed	Distribution of neuronal nicotinic acetylcholine receptor gene restriction fragment length polymorphisms in inbred and partially inbred mice.	CHRNA3 CHRNA4 CHRNB4	2.11e-06	7	138	3	8563774
Pubmed	Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.	CHRNA3 CHRNA4 CHRNB4	2.11e-06	7	138	3	9009220
Pubmed	Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.	CHRNA3 CHRNA4 CHRNB4	2.11e-06	7	138	3	1505988
Pubmed	Generation and characterization of Rac3 knockout mice.	RAC1 RAC2 RAC3	3.37e-06	8	138	3	15964829
Pubmed	Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production.	PTGER2 PTGER4 NOS2	3.37e-06	8	138	3	19098906
Pubmed	Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.	RAC1 RAC2 RAC3	3.37e-06	8	138	3	24598074
Pubmed	Functional interaction between Lypd6 and nicotinic acetylcholine receptors.	CHRNA3 CHRNA4 CHRNB4	3.37e-06	8	138	3	27344019
Pubmed	CYBA encoding p22(phox), the cytochrome b558 alpha polypeptide: gene structure, expression, role and physiopathology.	RAC1 RAC2 RAC3	3.37e-06	8	138	3	27048830
Pubmed	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.	CHRNA3 CHRNA4 CHRNB4	5.05e-06	9	138	3	8906617
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP10D ATP11B ATP11C ATP4A	5.22e-06	29	138	4	15071553
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP10D ATP11B ATP11C	7.19e-06	10	138	3	15919184
Pubmed	Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.	CHRNA3 CHRNA4 CHRNB4	7.19e-06	10	138	3	20736995
Pubmed	Regulation of lymphatic-blood vessel separation by endothelial Rac1.	RAC1 RAC2 RAC3	7.19e-06	10	138	3	19906871
Pubmed	Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission.	CHRNA3 CHRNA4 CHRNB4	9.85e-06	11	138	3	29791835
Pubmed	Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus.	CHRNA3 CHRNA4 CHRNB4	9.85e-06	11	138	3	12225896
Pubmed	The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation.	RAC1 RAC2 RAC3	9.85e-06	11	138	3	18786395
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR2J3 OR8K3 OR10X1 OR5D13	1.13e-05	35	138	4	16939646
Pubmed	ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.	ATP10D ATP11B ATP11C	1.31e-05	12	138	3	21914794
Pubmed	Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.	CHRNA3 CHRNA4 CHRNB4	1.31e-05	12	138	3	20584212
Pubmed	Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor.	CHRNA3 CHRNB4	1.56e-05	2	138	2	23884938
Pubmed	Inhibitory effect of prostaglandin E(2) on the migration of nasal fibroblasts.	PTGER2 PTGER4	1.56e-05	2	138	2	24980222
Pubmed	Pharmacological evidence that the inhibitory effects of prostaglandin E2 are mediated by the EP2 and EP4 receptors in human neutrophils.	PTGER2 PTGER4	1.56e-05	2	138	2	38345417
Pubmed	Characterization of the human beta4 nAChR gene and polymorphisms in CHRNA3 and CHRNB4.	CHRNA3 CHRNB4	1.56e-05	2	138	2	11450844
Pubmed	Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.	RAC1 RAC3	1.56e-05	2	138	2	36050459
Pubmed	Rac1 and Rac3 have opposite functions in Schwann cells during developmental myelination.	RAC1 RAC3	1.56e-05	2	138	2	33812927
Pubmed	Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.	RAC1 RAC3	1.56e-05	2	138	2	28066185
Pubmed	Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.	RAC1 RAC2	1.56e-05	2	138	2	15504745
Pubmed	Nicotinic receptor-mediated filtering of mitral cell responses to olfactory nerve inputs involves the α3β4 subtype.	CHRNA3 CHRNB4	1.56e-05	2	138	2	22378897
Pubmed	Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes.	CHRNA4 CHRNB4	1.56e-05	2	138	2	21343288
Pubmed	Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2.	PTGER2 PTGER4	1.56e-05	2	138	2	8250933
Pubmed	Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.	PTGER2 PTGER4	1.56e-05	2	138	2	8078484
Pubmed	Protective effect of prostaglandin E2 receptors EP2 and EP4 in alloimmune response in vivo.	PTGER2 PTGER4	1.56e-05	2	138	2	17175225
Pubmed	Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.	RAC1 RAC2	1.56e-05	2	138	2	15528331
Pubmed	Modulation of host natural killer cell functions in breast cancer via prostaglandin E2 receptors EP2 and EP4.	PTGER2 PTGER4	1.56e-05	2	138	2	22306906
Pubmed	Dispensable role of Rac1 and Rac3 after cochlear hair cell specification.	RAC1 RAC3	1.56e-05	2	138	2	37204479
Pubmed	Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2.	RAC1 RAC2	1.56e-05	2	138	2	19955208
Pubmed	Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2.	PTGER2 PTGER4	1.56e-05	2	138	2	26639895
Pubmed	The PGE(2)-EP4 receptor is necessary for stimulation of the renin-angiotensin-aldosterone system in response to low dietary salt intake in vivo.	PTGER2 PTGER4	1.56e-05	2	138	2	22993066
Pubmed	Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.	RAC1 RAC2	1.56e-05	2	138	2	14564009
Pubmed	27-Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action.	SLC22A12 CYP7B1	1.56e-05	2	138	2	33368618
Pubmed	Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.	RAC1 RAC3	1.56e-05	2	138	2	31369617
Pubmed	Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice.	RAC1 RAC2	1.56e-05	2	138	2	21511011
Pubmed	Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid.	RAC1 RAC2	1.56e-05	2	138	2	12027902
Pubmed	Rac regulates PtdInsP₃ signaling and the chemotactic compass through a redox-mediated feedback loop.	RAC1 RAC2	1.56e-05	2	138	2	21976675
Pubmed	Prostaglandin E2 inhibits elastogenesis in the ductus arteriosus via EP4 signaling.	PTGER2 PTGER4	1.56e-05	2	138	2	24146253
Pubmed	Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.	RAC1 RAC2	1.56e-05	2	138	2	21940819
Pubmed	Prostaglandin E2 receptor subtype EP2- and EP4-regulated gene expression profiling in human ciliary smooth muscle cells.	PTGER2 PTGER4	1.56e-05	2	138	2	20551148
Pubmed	The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.	CHRNA3 CHRNB4	1.56e-05	2	138	2	15275829
Pubmed	Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P.	OCA2 CRYAA	1.56e-05	2	138	2	16453125
Pubmed	Association Between Nicotine-dependent Gene Polymorphism and Smoking Cessation in Patients With Lung Cancer.	CHRNA3 CHRNA4	1.56e-05	2	138	2	31402126
Pubmed	Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions.	RAC1 RAC2	1.56e-05	2	138	2	12391220
Pubmed	Cutting edge: Rac GTPases sensitize activated T cells to die via Fas.	RAC1 RAC2	1.56e-05	2	138	2	17982024
Pubmed	Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease.	RAC1 RAC2	1.56e-05	2	138	2	17996650
Pubmed	Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.	RAC1 RAC2	1.56e-05	2	138	2	26496249
Pubmed	Binding interactions with the complementary subunit of nicotinic receptors.	CHRNA4 CHRNB4	1.56e-05	2	138	2	23349463
Pubmed	Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration.	PTGER2 PTGER4	1.56e-05	2	138	2	11093764
Pubmed	Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E2 Activation in Human Podocytes.	PTGER2 PTGER4	1.56e-05	2	138	2	32438662
Pubmed	Tissue and zonal-specific expression of an olfactory receptor transgene.	OR10H4 OR10H3	1.56e-05	2	138	2	9412503
Pubmed	Prostaglandin E2 suppresses lipopolysaccharide-stimulated IFN-beta production.	PTGER2 PTGER4	1.56e-05	2	138	2	18250418
Pubmed	Functional role of iNOS-Rac2 interaction in neutrophil extracellular traps (NETs) induced cytotoxicity in sepsis.	NOS2 RAC2	1.56e-05	2	138	2	33309799
Pubmed	Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.	RAC1 RAC3	1.56e-05	2	138	2	21949760
Pubmed	Alpha 3, alpha 5, and beta 4: three members of the rat neuronal nicotinic acetylcholine receptor-related gene family form a gene cluster.	CHRNA3 CHRNB4	1.56e-05	2	138	2	1689727
Pubmed	Efficient T-cell priming and activation requires signaling through prostaglandin E2 (EP) receptors.	PTGER2 PTGER4	1.56e-05	2	138	2	26051593
Pubmed	Rac1 and Rac2 control distinct events during antigen-stimulated mast cell exocytosis.	RAC1 RAC2	1.56e-05	2	138	2	24399839
Pubmed	STING Contributes to Pulmonary Hypertension by Targeting IFN and BMPR2 Signaling through Regulating of F2RL3.	F2RL3 STING1	1.56e-05	2	138	2	38864771
Pubmed	PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4).	PTGER2 PTGER4	1.56e-05	2	138	2	23337716
Pubmed	Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.	RAC1 RAC3	1.56e-05	2	138	2	26582364
Pubmed	Prostaglandin E2 prevents hyperosmolar-induced human mast cell activation through prostanoid receptors EP2 and EP4.	PTGER2 PTGER4	1.56e-05	2	138	2	25329458
Pubmed	EP4 agonist inhibits lipopolysaccharide-induced mucus secretion in airway epithelial cells.	PTGER2 PTGER4	1.56e-05	2	138	2	18254372
Pubmed	Rac2 is required for the formation of neutrophil extracellular traps.	RAC1 RAC2	1.56e-05	2	138	2	21712395
Pubmed	Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits invasion of human immortalized endometriotic epithelial and stromal cells through suppression of metalloproteinases.	PTGER2 PTGER4	1.56e-05	2	138	2	21111772
Pubmed	Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity.	PTGER2 NOS2	1.56e-05	2	138	2	15920732
Pubmed	Potential therapeutic interventions via EP2/EP4 prostaglandin receptors.	PTGER2 PTGER4	1.56e-05	2	138	2	22706114
Pubmed	Prostaglandin E2 regulates tumor angiogenesis in prostate cancer.	PTGER2 PTGER4	1.56e-05	2	138	2	18829529
Pubmed	Infection of human dendritic cells with herpes simplex virus type 1 dramatically diminishes the mRNA levels of the prostaglandin E(2) receptors EP2 and EP4.	PTGER2 PTGER4	1.56e-05	2	138	2	18086382
Pubmed	PGE2 promotes Ca2+-mediated epithelial barrier disruption through EP1 and EP4 receptors in Caco-2 cell monolayers.	PTGER2 PTGER4	1.56e-05	2	138	2	20484658
Pubmed	Prostaglandin E2 directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF-β signalling.	PTGER2 PTGER4	1.56e-05	2	138	2	34529833
Interaction	ARL6IP5 interactions	RHOD MYCBP2 STING1 SLC22A9 ZDHHC22 ZRANB1 ATP4A RAC1 RAC2 RAC3	1.41e-07	192	114	10	int:ARL6IP5
Interaction	FLVCR1 interactions	RHOD STING1 SLC22A9 ZACN ZRANB1 RAC1 RAC2 RAC3	1.45e-07	105	114	8	int:FLVCR1
Interaction	LRRC8A interactions	RHOD CHRNA4 ZACN ZRANB1 RAC1 RAC2 RAC3	5.28e-07	85	114	7	int:LRRC8A
Interaction	SOWAHC interactions	RHOD STING1 ZRANB1 RAC1 RAC3	5.65e-07	29	114	5	int:SOWAHC
Interaction	DCBLD1 interactions	RHOD TNFSF8 RAC1 RAC2 RAC3	8.01e-07	31	114	5	int:DCBLD1
Interaction	SLC16A3 interactions	RHOD STING1 ZRANB1 RAC1 RAC2 RAC3	8.23e-07	57	114	6	int:SLC16A3
Interaction	SLC16A7 interactions	RHOD STING1 RAC1 RAC2 RAC3	9.45e-07	32	114	5	int:SLC16A7
Interaction	ABCC1 interactions	ABCC1 RHOD STING1 TMEM33 ZRANB1 RAC1 RAC2 RAC3	1.46e-06	142	114	8	int:ABCC1
Interaction	ATP11A interactions	RHOD ATP11C RAC1 RAC2 RAC3	1.50e-06	35	114	5	int:ATP11A
Interaction	MAP4K4 interactions	DENND4A RHOD MYCBP2 STING1 FRY ZRANB1 RAC1 RAC2 HTT RAC3	1.83e-06	254	114	10	int:MAP4K4
Interaction	IGSF3 interactions	MYADM RHOD CNTNAP2 RAC1 RAC2 RAC3	3.05e-06	71	114	6	int:IGSF3
Interaction	JAG1 interactions	STING1 ZRANB1 RAC1 RAC2 RAC3	3.38e-06	41	114	5	int:JAG1
Interaction	C2CD2 interactions	RHOD TNFSF8 RAC1 RAC2 RAC3	4.83e-06	44	114	5	int:C2CD2
Interaction	ADD1 interactions	RHOD XPO5 UBIAD1 ZRANB1 RAC1 RAC2 HTT RAC3	5.85e-06	171	114	8	int:ADD1
Interaction	SLC7A11 interactions	RHOD STING1 TNFSF8 RAC1 RAC2 RAC3	7.08e-06	82	114	6	int:SLC7A11
Interaction	CNNM3 interactions	RHOD STING1 SLC22A9 TNFSF8 ZRANB1 RAC1 RAC2 RAC3	8.18e-06	179	114	8	int:CNNM3
Interaction	BLTP1 interactions	RHOD STING1 RAC1 RAC2 RAC3	8.29e-06	49	114	5	int:BLTP1
Interaction	CABLES1 interactions	RHOD CABLES1 RAC1 RAC2 RAC3	9.17e-06	50	114	5	int:CABLES1
Interaction	SLC38A2 interactions	RHOD TMEM237 STING1 ZRANB1 RAC1 RAC2 RAC3	9.64e-06	131	114	7	int:SLC38A2
Interaction	ABCC5 interactions	RHOD STING1 RAC1 RAC2 RAC3	1.01e-05	51	114	5	int:ABCC5
Interaction	SLC12A7 interactions	RHOD TMEM237 STING1 ZRANB1 RAC1 RAC2 RAC3	1.01e-05	132	114	7	int:SLC12A7
Interaction	SLC2A1 interactions	RHOD ADARB1 STT3A ATP11C ZRANB1 RAC1 RAC2 HTT RAC3	1.14e-05	247	114	9	int:SLC2A1
Interaction	VAMP3 interactions	RHOD TMEM237 STING1 CRYAA ATP11C ZRANB1 ATP4A RAC1 RAC2 RAC3	1.19e-05	314	114	10	int:VAMP3
Interaction	PLPPR3 interactions	PLPPR1 CHRNA4 ZACN CNTNAP2	1.32e-05	26	114	4	int:PLPPR3
Interaction	SLITRK4 interactions	RHOD RAC1 RAC2 RAC3	1.32e-05	26	114	4	int:SLITRK4
Interaction	RAB23 interactions	RHOD PLPPR1 RAC1 RAC2 RAC3	1.34e-05	54	114	5	int:RAB23
Interaction	SLC35B2 interactions	RHOD TMEM237 STING1 SLC22A9 ZRANB1 RAC1	1.38e-05	92	114	6	int:SLC35B2
Interaction	STT3B interactions	ABCC1 RHOD STING1 STT3A SLC22A9 ZRANB1 RAC1 RAC2 RAC3	1.52e-05	256	114	9	int:STT3B
Interaction	C2CD5 interactions	KNTC1 RHOD CABLES1 RAC1 RAC2 RAC3	1.66e-05	95	114	6	int:C2CD5
Interaction	TBC1D5 interactions	RHOD MYCBP2 STING1 ZRANB1 RAC1 RAC2	1.66e-05	95	114	6	int:TBC1D5
Interaction	RAB11A interactions	ABCC1 DENND4A DNAJC13 SLC30A4 STT3A ATP11B SLCO4C1 XPO5 NAT10 SEMA4A UBIAD1 ZRANB1 ATP4A RAC1 RAC2 HTT	1.75e-05	830	114	16	int:RAB11A
Interaction	ADD3 interactions	RHOD CNTNAP2 ZRANB1 RAC1 RAC2 HTT RAC3	1.79e-05	144	114	7	int:ADD3
Interaction	TMEM237 interactions	RHOD TMEM237 STING1 SLC35E4 ZRANB1 RAC1 RAC2 RAC3	1.97e-05	202	114	8	int:TMEM237
Interaction	FLRT2 interactions	RHOD RAC1 RAC2 RAC3	2.07e-05	29	114	4	int:FLRT2
Interaction	SLITRK5 interactions	RHOD CNTNAP2 RAC1 RAC2 RAC3	2.08e-05	59	114	5	int:SLITRK5
Interaction	TMTC3 interactions	RHOD CHRNA4 CHRNB4 ZACN ZRANB1 RAC1	2.22e-05	100	114	6	int:TMTC3
Interaction	DOCK9 interactions	RHOD CNTNAP2 RAC1 RAC2 RAC3	2.45e-05	61	114	5	int:DOCK9
Interaction	PLCB4 interactions	RHOD RAC1 RAC2 RAC3	3.09e-05	32	114	4	int:PLCB4
Interaction	NECTIN2 interactions	USP53 RHOD TNFSF8 FUT9 RAC1 RAC2 RAC3	3.38e-05	159	114	7	int:NECTIN2
Interaction	DHRS7B interactions	RHOD STING1 SLC22A9 ZRANB1 RAC1 RAC2	3.62e-05	109	114	6	int:DHRS7B
Interaction	SUN1 interactions	RHOD STING1 ZACN RAC1 HERC5 RAC2 RAC3	3.66e-05	161	114	7	int:SUN1
Interaction	ADGRE5 interactions	ADARB1 CHRNB4 ZACN TNFSF8 ALG6 RAC1 RAC3	3.97e-05	163	114	7	int:ADGRE5
Interaction	MFAP3 interactions	CHRNA3 CHRNB4 ZACN RAC1 RAC3	4.16e-05	68	114	5	int:MFAP3
Interaction	CD99 interactions	RHOD ZRANB1 RAC1 RAC2 RAC3	4.16e-05	68	114	5	int:CD99
Interaction	SLC20A2 interactions	RHOD STING1 RAC1 RAC2 RAC3	4.16e-05	68	114	5	int:SLC20A2
Interaction	DIAPH2 interactions	RHOD STING1 RAC1 RAC2 RAC3	4.16e-05	68	114	5	int:DIAPH2
Interaction	TMEM9 interactions	KNTC1 STING1 MDN1 XPO5 TNFSF8 RAC1 RAC2 RAC3	4.39e-05	226	114	8	int:TMEM9
Interaction	SLC39A14 interactions	RHOD STING1 ZRANB1 RAC1 RAC2 RAC3	4.43e-05	113	114	6	int:SLC39A14
Interaction	RASA3 interactions	RHOD RAC1 RAC2 RAC3	4.44e-05	35	114	4	int:RASA3
Interaction	CLDND1 interactions	MYADM RHOD SLC44A5 RAC1 RAC3	4.79e-05	70	114	5	int:CLDND1
Interaction	ZDHHC20 interactions	STING1 RAC1 RAC2 RAC3	4.97e-05	36	114	4	int:ZDHHC20
Interaction	PCDH17 interactions	RHOD RAC1 RAC2 RAC3	4.97e-05	36	114	4	int:PCDH17
Interaction	ADGRG6 interactions	TNFSF8 RAC1 RAC2 RAC3	4.97e-05	36	114	4	int:ADGRG6
Interaction	PIGN interactions	TMEM126A MYCBP2 STING1 CHRNA4 SLC22A9	5.13e-05	71	114	5	int:PIGN
Interaction	MUC13 interactions	RHOD RAC1 RAC2 RAC3	5.55e-05	37	114	4	int:MUC13
Interaction	MPZL1 interactions	RHOD STING1 CHRNA4 RAC1 RAC2 RAC3	5.65e-05	118	114	6	int:MPZL1
Interaction	SLC9A1 interactions	RHOD STING1 SLCO4C1 RAC1 RAC2 RAC3	5.65e-05	118	114	6	int:SLC9A1
Interaction	SLC11A2 interactions	RHOD RAC1 RAC2 RAC3	6.18e-05	38	114	4	int:SLC11A2
Interaction	CPD interactions	RHOD STING1 ZRANB1 ATP4A RAC1 RAC2 RAC3	6.22e-05	175	114	7	int:CPD
Interaction	HLA-B interactions	ABCC1 RHOD CHRNA4 MDN1 RAC1 RAC2 HTT RAC3	6.50e-05	239	114	8	int:HLA-B
Interaction	EMC3 interactions	RHOD TMEM237 TMEM33 RAC1 RAC2 RAC3	6.50e-05	121	114	6	int:EMC3
Interaction	SLC29A1 interactions	RHOD STING1 SLC22A9 RAC1 RAC2 RAC3	6.50e-05	121	114	6	int:SLC29A1
Interaction	LSR interactions	RHOD CHRNA4 CHRNB4 ZRANB1 RAC1 RAC2 RAC3	6.69e-05	177	114	7	int:LSR
Interaction	HACD3 interactions	RHOD STING1 SERINC3 NOS2 ZRANB1 RAC1 RAC2 RAC3	7.09e-05	242	114	8	int:HACD3
Interaction	RELL1 interactions	RHOD ZRANB1 RAC1 RAC2 RAC3	7.11e-05	76	114	5	int:RELL1
Interaction	GNB4 interactions	SLC30A4 FZD10 RAC1 RAC2 HTT RAC3	7.12e-05	123	114	6	int:GNB4
Interaction	SLC6A6 interactions	RHOD STING1 RAC1 RAC2	7.58e-05	40	114	4	int:SLC6A6
Interaction	DIAPH3 interactions	TMEM126A RHOD STING1 RAC1 RAC2 RAC3	7.79e-05	125	114	6	int:DIAPH3
Interaction	CDC42EP4 interactions	RHOD ZRANB1 RAC1 RAC2 RAC3	8.06e-05	78	114	5	int:CDC42EP4
Interaction	NECTIN3 interactions	RHOD STING1 RAC1 RAC2 RAC3	8.06e-05	78	114	5	int:NECTIN3
Interaction	MACF1 interactions	RHOD MYCBP2 STING1 CNTNAP2 ZRANB1 RAC1 RAC2 RAC3	8.18e-05	247	114	8	int:MACF1
Interaction	ANO6 interactions	RHOD STING1 CHRNB4 ZRANB1 RAC1 RAC2	8.51e-05	127	114	6	int:ANO6
Interaction	PPP1R9A interactions	RHOD MYCBP2 ZRANB1 RAC1 RAC2 RAC3	8.89e-05	128	114	6	int:PPP1R9A
Interaction	SLC12A4 interactions	RHOD STING1 ZRANB1 RAC1 RAC2 RAC3	9.28e-05	129	114	6	int:SLC12A4
Interaction	RAB11FIP5 interactions	RHOD NOS2 ZRANB1 RAC1 RAC2 HTT RAC3	9.44e-05	187	114	7	int:RAB11FIP5
Interaction	ARHGDIB interactions	STING1 RAC1 RAC2 RAC3	1.01e-04	43	114	4	int:ARHGDIB
Interaction	CLCC1 interactions	RHOD STING1 ZACN ZRANB1 RAC1 RAC2 RAC3	1.04e-04	190	114	7	int:CLCC1
Interaction	TRPM7 interactions	RHOD STING1 ZACN RAC1 RAC2 RAC3	1.05e-04	132	114	6	int:TRPM7
Interaction	GOSR2 interactions	RHOD STING1 SLC30A4 CHRNA4 ZRANB1 RAC2	1.05e-04	132	114	6	int:GOSR2
Interaction	KRIT1 interactions	RHOD RAC1 RAC2 RAC3	1.11e-04	44	114	4	int:KRIT1
Interaction	ROCK1 interactions	RHOD STING1 ZRANB1 RAC1 RAC2 HTT RAC3	1.11e-04	192	114	7	int:ROCK1
Interaction	DAG1 interactions	RHOD STING1 TNFSF8 RAC1 RAC2 RAC3	1.14e-04	134	114	6	int:DAG1
Interaction	MTARC2 interactions	RHOD STING1 RAC2 RAC3	1.21e-04	45	114	4	int:MTARC2
Interaction	ADGRL1 interactions	RHOD CNTNAP2 RAC1 RAC2 RAC3	1.21e-04	85	114	5	int:ADGRL1
Interaction	SLC12A2 interactions	RHOD STING1 ZACN ATP4A RAC1 RAC2 RAC3	1.23e-04	195	114	7	int:SLC12A2
Interaction	EHBP1 interactions	RHOD CNTNAP2 ZRANB1 RAC1 RAC2 RAC3	1.29e-04	137	114	6	int:EHBP1
Interaction	SLC7A1 interactions	RHOD TMEM237 STING1 ZRANB1 RAC1 RAC2 RAC3	1.31e-04	197	114	7	int:SLC7A1
Interaction	ITGA1 interactions	RHOD RAC1 RAC2 RAC3	1.32e-04	46	114	4	int:ITGA1
Interaction	SLCO4A1 interactions	RHOD STING1 RAC1 RAC3	1.32e-04	46	114	4	int:SLCO4A1
Interaction	EMC1 interactions	ZMPSTE24 RHOD TMEM237 STT3A ZACN XPO5 ZRANB1 RAC1 RAC2 RAC3	1.32e-04	418	114	10	int:EMC1
Interaction	TNS3 interactions	RHOD STING1 ZRANB1 RAC1 RAC2	1.35e-04	87	114	5	int:TNS3
Interaction	RALGAPA1 interactions	GARNL3 RHOD ZRANB1 RAC1 RAC3	1.35e-04	87	114	5	int:RALGAPA1
Interaction	SLC16A1 interactions	GARNL3 RHOD STING1 SERINC3 ZRANB1 RAC1 RAC2	1.43e-04	200	114	7	int:SLC16A1
Interaction	SLC20A1 interactions	STING1 CRYAA SLC22A9 RAC1 RAC3	1.51e-04	89	114	5	int:SLC20A1
Interaction	SLC35E4 interactions	TMEM237 STING1 SLC35E4	1.60e-04	19	114	3	int:SLC35E4
Interaction	B2M interactions	ZRANB1 RAC1 HERC5 RAC2 RAC3	1.76e-04	92	114	5	int:B2M
Interaction	STEAP3 interactions	RHOD STING1 CHRNA4 RAC1 RAC2 RAC3	1.83e-04	146	114	6	int:STEAP3
Interaction	ERMP1 interactions	TMEM237 STING1 CHRNA4 CHRNB4 ZACN ZRANB1	1.90e-04	147	114	6	int:ERMP1
Interaction	ANKLE2 interactions	RHOD STING1 ABCA6 ZRANB1 RAC2 HTT RAC3	1.94e-04	210	114	7	int:ANKLE2
Interaction	LMF1 interactions	STING1 CHRNB4 SLC22A9 FUT9	1.98e-04	51	114	4	int:LMF1
Cytoband	9q31.1	OR13C5 OR13C8 OR13C4 PLPPR1 OR13C9 OR13C2	2.73e-09	41	138	6	9q31.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	OR13C5 OR13C8 OR13C4 PLPPR1 OR13C9 OR13C2	3.93e-06	137	138	6	chr9q31
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	STT3A OR8B3 OR8B8 OR4D5 OR8D4 OR8B2	2.61e-05	191	138	6	chr11q24
Cytoband	11q24.1	OR4D5 OR8D4 OR8B2	1.92e-04	37	138	3	11q24.1
Cytoband	1q44	OR2L3 OR2M2 OR2G2 OR2M3	3.53e-04	110	138	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2L3 OR2M2 OR2G2 OR2M3	6.25e-04	128	138	4	chr1q44
GeneFamily	Solute carriers	SLC37A1 SLC29A3 SLC22A25 SLC6A17 SLC7A7 SLC30A4 SLC22A12 SLC7A9 SLC22A9 SLCO4C1 SLC44A5 SLC41A3 SLC35E4 SLC45A1 SLC4A11	1.68e-08	395	110	15	752
GeneFamily	Olfactory receptors, family 2	OR2L3 OR2M2 OR2B2 OR2G2 OR2J3 OR2B3 OR2M3 OR2B6 OR2A12	2.89e-08	113	110	9	149
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C8 OR13C4 OR13C9 OR13C2	2.35e-07	23	110	5	162
GeneFamily	Rho family GTPases	RHOD RAC1 RAC2 RAC3	5.83e-06	20	110	4	390
GeneFamily	Olfactory receptors, family 8	OR8K3 OR8B3 OR8B8 OR8D4 OR8B2	1.17e-05	49	110	5	155
GeneFamily	ATPase phospholipid transporting	ATP10D ATP11B ATP11C	9.45e-05	15	110	3	1210
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA3 CHRNA4 CHRNB4	1.16e-04	16	110	3	173
GeneFamily	Olfactory receptors, family 10	OR10H4 OR10T2 OR10X1 OR10H3	6.99e-04	66	110	4	157
GeneFamily	Prostaglandin (prostanoid) receptors	PTGER2 PTGER4	1.28e-03	9	110	2	207
GeneFamily	Cyclins\|F-boxes other	ECT2L FBXO16 FBXO41	1.71e-03	39	110	3	560
GeneFamily	ATP binding cassette subfamily A	ABCA8 ABCA6	3.18e-03	14	110	2	805
ToppCell	droplet-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A HID1 STING1 TNFSF8 NKG7 PIK3R5 RAC2	1.34e-06	178	137	7	12d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCell	droplet-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A HID1 STING1 TNFSF8 NKG7 PIK3R5 RAC2	1.34e-06	178	137	7	e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCell	droplet-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A HID1 STING1 TNFSF8 NKG7 PIK3R5 RAC2	1.34e-06	178	137	7	11c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8\|bone_marrow / Manually curated celltypes from each tissue	RHOD PAQR8 PTGER2 PTGER4 TNFSF8 CACNA1I	8.28e-06	154	137	6	93145a1bc5712ae664690b03a9e00ce1f92cfc7e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	F2RL3 HID1 PTGER4 NKG7 UNC79 RAC3	1.03e-05	160	137	6	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KNTC1 NPY2R PLPPR1 CHRNA3 SLC44A5	1.52e-05	101	137	5	6523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GARNL3 GPR84 STING1 SLC41A3 PIK3R5 RAC2	1.77e-05	176	137	6	d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GARNL3 GPR84 STING1 SLC41A3 PIK3R5 RAC2	1.77e-05	176	137	6	4f37854124d77ee64dcb40fd491eaed2ba389891
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GARNL3 GPR84 STING1 SLC41A3 PIK3R5 RAC2	1.77e-05	176	137	6	0afba8707b847e5bdf6f38fe4379967631fe2240
ToppCell	facs-Lung-EPCAM-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR33 PTGER4 CHRNA3 FUT9 SEMA4A PIK3R5	1.83e-05	177	137	6	d445167dae956e641386f84ab3ae9f47c089e09a
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MYCBP2 CHRNA4 CNTNAP2 FBXO41 SLC45A1 UNC79	2.42e-05	186	137	6	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
Drug	2-(1'-methyl-2'-pyrrolidinyl)-7-hydroxy-1,4-benzodioxane	CHRNA3 CHRNA4 CHRNB4	8.12e-07	4	135	3	ctd:C569671
Drug	Anabasine	CHRNA3 CHRNA4 CHRNB4	8.12e-07	4	135	3	ctd:D000691
Drug	N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline	CHRNA3 CHRNA4 CHRNB4	2.02e-06	5	135	3	ctd:C524978
Drug	cisatracurium	CHRNA3 CHRNA4 CHRNB4	2.02e-06	5	135	3	ctd:C101584
Drug	B258	RAC1 RAC2 RAC3	4.02e-06	6	135	3	CID000593690
Drug	decamethonium	CHRNA3 CHRNA4 CHRNB4	4.02e-06	6	135	3	ctd:C033019
Drug	Atracurium	CHRNA3 CHRNA4 CHRNB4	7.01e-06	7	135	3	ctd:D001279
Drug	mivacurium	CHRNA3 CHRNA4 CHRNB4	7.01e-06	7	135	3	ctd:C049430
Drug	EPTC	CHRNA3 CHRNA4 CHRNB4	7.01e-06	7	135	3	ctd:C036251
Drug	Dimethylphenylpiperazinium Iodide	CHRNA3 CHRNA4 CHRNB4	1.12e-05	8	135	3	ctd:D004246
Drug	epibatidine	CHRNA3 CHRNA4 CHRNB4	1.12e-05	8	135	3	ctd:C082748
Drug	fenoxycarb	CHRNA3 CHRNA4 CHRNB4	1.67e-05	9	135	3	ctd:C052034
Drug	methylcarbamylcholine	HTR1D CHRNA3 CHRNA4 ZACN	1.87e-05	27	135	4	CID000004136
Drug	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	ABCC1 PTGER2 PTGER4 CHRNA4 CHRNB4 NOS2	2.33e-05	96	135	6	ctd:C080955
Drug	dihydrorhodamine 123	KNTC1 ABCC1 SLC7A7 NOS2 RAC2	2.42e-05	58	135	5	CID000105032
Drug	cytisine	CHRNA3 CHRNA4 CHRNB4	3.25e-05	11	135	3	ctd:C004712
Drug	Dihydro-beta-Erythroidine	CHRNA3 CHRNA4 CHRNB4	3.25e-05	11	135	3	ctd:D004079
Drug	Pancuronium	CHRNA3 CHRNA4 CHRNB4	3.25e-05	11	135	3	ctd:D010197
Drug	rocuronium	CHRNA3 CHRNA4 CHRNB4	3.25e-05	11	135	3	ctd:C061870
Drug	quinuclidine	CHRNA3 CHRNA4 STT3A ZACN	3.28e-05	31	135	4	CID000007527
Drug	cytisine	HTR1D CHRNA3 CHRNA4 ZACN	4.23e-05	33	135	4	CID000010235
Drug	Vecuronium Bromide	CHRNA3 CHRNA4 CHRNB4	4.31e-05	12	135	3	ctd:D014673
Drug	Te Al	RAC1 RAC2 HTT RAC3	5.37e-05	35	135	4	CID000168005
Drug	(+/-)-Epibatidine	HTR1D CHRNA3 CHRNA4 ZACN	5.37e-05	35	135	4	CID000001204
Drug	16,16-Dimethylprostaglandin E2	PTGER2 PTGER4 NOS2	5.58e-05	13	135	3	ctd:D015064
Drug	Tubocurarine,d	HTR1D CHRNA3 CHRNA4 ZACN RAC1	6.92e-05	72	135	5	CID000001210
Drug	Varenicline	CHRNA3 CHRNA4 CHRNB4	7.07e-05	14	135	3	ctd:D000068580
Drug	ZK110841	PTGER2 PTGER4 HTT	8.80e-05	15	135	3	CID005311503
Drug	AY-22093	PTGER2 PTGER4	1.04e-04	3	135	2	CID000193037
Drug	Misoprostol	PTGER2 PTGER4	1.04e-04	3	135	2	DB00929
Drug	GW627368X	PTGER2 PTGER4	1.04e-04	3	135	2	CID005312130
Drug	1,2-bis-N-cytisinylethane	CHRNA3 CHRNB4	1.04e-04	3	135	2	ctd:C482518
Drug	Hexamethonium	CHRNA3 CHRNA4 CHRNB4	1.08e-04	16	135	3	ctd:D018738
Disease	autosomal dominant intellectual developmental disorder 48 (implicated_via_orthology)	RAC1 RAC2 RAC3	8.75e-08	3	132	3	DOID:0080235 (implicated_via_orthology)
Disease	smoking behavior, carbon monoxide exhalation measurement	CHRNA3 CHRNB4	1.99e-05	2	132	2	EFO_0004318, EFO_0006520
Disease	Generalized seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0234533
Disease	Clonic Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0234535
Disease	Convulsive Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0751494
Disease	Seizures, Sensory	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0751496
Disease	Non-epileptic convulsion	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0751056
Disease	Atonic Absence Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0751123
Disease	Complex partial seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0149958
Disease	Single Seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0751110
Disease	Nonepileptic Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C3495874
Disease	Visual seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0270824
Disease	Epileptic drop attack	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0270846
Disease	Vertiginous seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0422855
Disease	Gustatory seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0422854
Disease	Seizures, Somatosensory	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0422850
Disease	Olfactory seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0422853
Disease	Seizures, Auditory	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0422852
Disease	Generalized Absence Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C4505436
Disease	Jacksonian Seizure	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C0022333
Disease	Epileptic Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.32e-05	101	132	5	C4317109
Disease	Absence Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.77e-05	102	132	5	C4316903
Disease	Convulsions	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.77e-05	102	132	5	C4048158
Disease	Tonic Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	9.77e-05	102	132	5	C0270844
Disease	Seizures, Focal	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	1.07e-04	104	132	5	C0751495
Disease	Myoclonic Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	1.07e-04	104	132	5	C4317123
Disease	Tonic - clonic seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	1.07e-04	104	132	5	C0494475
Disease	Physiological Sexual Disorders	PTGER2 PTGER4	1.18e-04	4	132	2	C0237873
Disease	Cis-4-decenoyl carnitine measurement	ABCC1 SLC44A5	1.97e-04	5	132	2	EFO_0022091
Disease	decenoylcarnitine measurement	ABCC1 SLC44A5	1.97e-04	5	132	2	EFO_0021803
Disease	alcohol use disorder (implicated_via_orthology)	CHRNA3 CHRNA4 UNC79 RAC1 RAC2 RAC3	2.53e-04	195	132	6	DOID:1574 (implicated_via_orthology)
Disease	nicotine dependence (is_implicated_in)	CHRNA3 CHRNA4	2.94e-04	6	132	2	DOID:0050742 (is_implicated_in)
Disease	nonanoylcarnitine (C9) measurement	ABCC1 SLC44A5	2.94e-04	6	132	2	EFO_0800381
Disease	emphysema imaging measurement	MYCBP2 CHRNA3 CHRNA4 OR8B3 OR8B2	5.17e-04	146	132	5	EFO_0007626
Disease	helping behavior measurement	TMEM33 USH2A	5.46e-04	8	132	2	EFO_0008538
Disease	5-hydroxylysine measurement	CHRNB4 SLC7A9	5.46e-04	8	132	2	EFO_0800002
Disease	cis-4-decenoylcarnitine (C10:1) measurement	ABCC1 SLC44A5	5.46e-04	8	132	2	EFO_0800311
Disease	octanoylcarnitine measurement	ABCC1 SLC44A5	7.00e-04	9	132	2	EFO_0021042
Disease	kidney disease (implicated_via_orthology)	RAC1 RAC2 RAC3	8.24e-04	41	132	3	DOID:557 (implicated_via_orthology)
Disease	estrogen measurement	SLC22A25 SLC22A9	8.73e-04	10	132	2	EFO_0011007
Disease	Alcohol Use Disorder	NPY2R CHRNA3 CCKAR	1.01e-03	44	132	3	C0001956
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	MYCBP2 SLCO4C1	1.06e-03	11	132	2	EFO_0801871
Disease	methionine sulfone measurement	SLC7A7 SLC7A9	1.27e-03	12	132	2	EFO_0800072
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA3 CHRNA4	1.27e-03	12	132	2	C1861063
Disease	decanoylcarnitine measurement	ABCC1 SLC44A5	1.27e-03	12	132	2	EFO_0021039
Disease	Alcoholic Intoxication, Chronic	NPY2R CHRNA3 CHRNA4 CCKAR CHRNB4 CNTNAP2	1.34e-03	268	132	6	C0001973
Disease	cognitive inhibition measurement	OR13C9 OR13C2 USH2A	1.47e-03	50	132	3	EFO_0007969
Disease	glutaroyl carnitine measurement	ABCC1 SLC44A5	1.50e-03	13	132	2	EFO_0021005
Disease	Manganese Poisoning	NOS2 HTT	1.74e-03	14	132	2	C0677050
Disease	Depressive disorder	SLC29A3 HTR1D CHRNA4 NOS2 RAC1 HTT	1.96e-03	289	132	6	C0011581
Disease	glycerol-3-phosphate measurement	OR5AU1 CNTNAP2	2.01e-03	15	132	2	EFO_0010488
Disease	Withdrawal Symptoms	NPY2R CHRNB4 NOS2	2.26e-03	58	132	3	C0087169
Disease	Drug Withdrawal Symptoms	NPY2R CHRNB4 NOS2	2.26e-03	58	132	3	C0086189
Disease	Substance Withdrawal Syndrome	NPY2R CHRNB4 NOS2	2.26e-03	58	132	3	C0038587
Disease	lung small cell carcinoma (is_marker_for)	CHRNA3 CHRNB4	2.29e-03	16	132	2	DOID:5409 (is_marker_for)
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA3 CHRNA4	2.29e-03	16	132	2	DOID:3635 (implicated_via_orthology)
Disease	Disorder of eye	TMEM126A TMEM237 OCA2 SEMA4A USH2A	2.70e-03	212	132	5	C0015397
Disease	disease free survival	CCDC168 CNTNAP2	2.90e-03	18	132	2	EFO_0000409
Disease	Seizures	PLPPR1 CHRNA3 CHRNA4 CHRNB4 NOS2	3.04e-03	218	132	5	C0036572
Disease	eye colour measurement	MYCBP2 OCA2 SLC7A7 USH2A ZRANB1	3.04e-03	218	132	5	EFO_0009764
Disease	skin pigmentation measurement	SLC6A17 OCA2 USH2A HYDIN	3.40e-03	137	132	4	EFO_0007009
Disease	Alcohol abuse	NPY2R CHRNA3 CCKAR	3.40e-03	67	132	3	C0085762
Disease	metabolite measurement	ABCC1 CHRNA3 SLC22A12 ATP10D CHRNB4 SLC7A9 SLC22A9 SLC44A5	3.79e-03	560	132	8	EFO_0004725
Disease	nose morphology measurement, mouth morphology measurement	OR4D5 OR8D4	3.94e-03	21	132	2	EFO_0007843, EFO_0007955
Disease	Liver diseases	CYP7B1 NOS2 RAC1	4.17e-03	72	132	3	C0023895
Disease	Liver Dysfunction	CYP7B1 NOS2 RAC1	4.17e-03	72	132	3	C0086565
Disease	pentachlorophenol measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022071
Disease	parathion measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022070
Disease	potassium chromate measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022072
Disease	mercuric chloride measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022068
Disease	heptachlor epoxide measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022067
Disease	methoxychlor measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022052
Disease	azinphos methyl measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022055
Disease	aldrin measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022054
Disease	dicofol measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022060
Disease	disulfoton measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022062
Disease	dieldrin measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022061
Disease	endrin measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022064
Disease	endosulfan measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022063
Disease	heptachlor measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022066
Disease	ethion measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022065
Disease	chlorpyrifos measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022057
Disease	cadmium chloride measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022056
Disease	diazinon measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022059
Disease	dibutyl phthalate measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0022058
Disease	environmental exposure measurement	ABCC1 PLPPR1 USH2A	4.33e-03	73	132	3	EFO_0008360

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTLLAILVFYLPSDC	CHRNB4	246	P30926
LISCLTVLVFYLPSE	CHRNA4	256	P43681
LVYILTSCSVFLSFF	DISP3	476	Q9P2K9
PTETESTVFCLFVYL	LINC00596	31	Q86U02
SFLTVLVFYLPSDCG	CHRNA3	256	P32297
FSISVRKYLPCFTFL	ALG6	421	Q9Y672
LTTSFNTIFSPTLYL	GPR33	286	Q49SQ1
ELSATDFLVCFIPYF	ABCA6	1191	Q8N139
SLYIFSFLSPKDLCA	ECT2L	86	Q008S8
PISFILLLSYTSSCV	CCKAR	351	P32238
LLLPFTTTYLCELGF	FAM200A	516	Q8TCP9
DPVFYLVCILTTSIA	ATP10D	1296	Q9P241
CSSPVFSRVLALEYF	CPNE6	66	O95741
STTIFLVFPFIAISC	OR2L3	201	Q8NG85
YESFSLPESVPLFCL	DENND4A	221	Q7Z401
FVVLCSILFSLYPDQ	OCA2	186	Q04671
LSFIDFCYSSVITPK	OR8B8	66	Q15620
SYPQTDVFLICFSLV	RAC2	71	P15153
DVFLICFSLVSPASY	RAC2	76	P15153
SYPQTDVFLICFSLV	RAC3	71	P60763
SYPQTDVFLICFSLV	RAC1	71	P63000
DLLVNTLCLPFTLTY	NPY2R	96	P49146
LVSLPFVCLCLYFSL	ANO10	316	Q9NW15
NVYLFSISPLSVLSC	DUOX1	1151	Q9NRD9
PCSLSQALTYFLDIT	NOS2	821	P35228
LSFLDFCYSSVITPK	OR8D4	66	Q8NGM9
ALSFSETCYTLTIVP	OR10X1	81	Q8NGY0
ISFAPCILQTFLYLA	OR2A12	91	Q8NGT7
FFLTNLSILDLCYTT	OR2B3	61	O76000
LSFLDICYTTSSIPS	OR13C4	66	Q8NGS5
FFLTNLSLLDLCYTT	OR2B6	61	P58173
FLYRCFTSSVIPQLL	OR2G2	71	Q8NGZ5
VPVLSSYSDLVLFFL	MDN1	4611	Q9NU22
LIPTISTCKFYLSFE	FUT9	231	Q9Y231
IFFYISLSGSECFLL	OR2M2	101	Q96R28
IFFYTSLLGSECFLL	OR2M3	101	Q8NG83
NLSFLDFCYISVTIP	OR14L1P	66	Q8NHC6
ITFAVCSLPFTIFAY	PTGER2	271	P43116
LCEYSTFILLFFSLS	PTGER4	91	P35408
SYLDSNCTIPLIFVL	DNAH12	2486	Q6ZR08
FETLNIPITYELFCS	KNTC1	1926	P50748
LFCLSASIIYPTTYV	MYADM	111	Q96S97
LSFLDICYTTTSIPS	OR13C5	66	Q8NGS8
LSFLDICYTTTSIPS	OR13C2	66	Q8NGS9
LSFIDLCYSSVFTPK	OR8B3	66	Q8NGG8
SLLSIFVEPIYFSSI	ADARB1	571	P78563
FLATYRTFVPTACLL	RGL3	96	Q3MIN7
DLLYCTLLQPFSVDT	GPR84	66	Q9NQS5
LALLSYQFSTFSPSL	NAT10	776	Q9H0A0
VLLGTSLTIPCYFID	ACAN	41	P16112
YLFLCALSISEILFT	OR10H3	61	O60404
YLFLCTLSVSEILFT	OR10H4	61	Q8NGA5
ILSFSESCYTFVIIP	OR10T2	66	Q8NGX3
ALTCFSVLFLPKYST	HERC5	991	Q9UII4
ACTDLLYLTSLPFLI	OXGR1	76	Q96P68
LALSTLNSCVDPFIY	F2RL3	326	Q96RI0
PLLLFILSSITYLTC	PAQR8	111	Q8TEZ7
YPDASVLLLCFDVTS	RHOD	86	O00212
PLACYLVIGTSFILS	FZD10	401	Q9ULW2
EFSLCLLFAKLVSYT	SLC37A1	331	P57057
IQELSFSPYLISCTV	HTT	1696	P42858
LYTLLAEACLPAFVT	HYDIN	3316	Q4G0P3
RLPLTLVYCFAFLTE	SDR42E1	281	Q8WUS8
SFCSIFSVLPYRDST	CABLES1	346	Q8TDN4
KPTSFAIICLSFSEY	SLC7A9	121	P82251
RSCLSSLQFVSPLYF	CACNA1I	1696	Q9P0X4
STCGAFYIPSVLLII	HTR1D	201	P28221
LLDFLTFALCAPYSE	DNAJC13	531	O75165
ALFCIFTYLDTRTLL	FBXO41	556	Q8TF61
ILFYFNLLRCTSPSV	SLC44A5	91	Q8NCS7
PCILLYISSFTTDFL	CNTNAP2	1061	Q9UHC6
YPFCSSIIFEITFTT	CYP7B1	181	O75881
LSEYCLPSILRTLFD	FRY	116	Q5TBA9
FLHLPSESSLTCYEL	CCDC168	4431	Q8NDH2
LFEYDLLPFLSSTIS	CRYAA	31	P02489
LSLYIFSFLDPRSLC	FBXO16	96	Q8IX29
FSPYNEVLSFCLTVL	ZMPSTE24	396	O75844
CITIYSSELFPTVLR	SLC22A12	451	Q96S37
AFAPTILVYCSLRFL	SLC22A25	191	Q6T423
YGILFSTLCTLPYSL	SLC45A1	671	Q9Y2W3
VSVSFLVLSCFPSLF	NKG7	71	Q16617
IELCTDIFPSVSLAY	ATP4A	821	P20648
IVCAFPYLLAFTTDS	GARNL3	756	Q5VVW2
VTTAYFFLPFLCLSI	MLNR	251	O43193
LSFLDFCYSSITAPR	OR4D5	66	Q8NGN0
FFLSNLSLLDLCYTT	OR2B2	61	Q9GZK3
VCSLILTYFLLDLSF	OR5D13	156	Q8NGL4
LSFIDLCYSSVFTPK	OR8B2	66	Q96RD0
AVIVTPFLCTIFSYL	OR1L4	206	Q8NGR5
LSFLDVCYTSSSVPL	OR13C8	66	Q8NGS7
VCYTSSSVPLILASF	OR13C8	71	Q8NGS7
LSFLDICYTTTSIPS	OR13C9	66	Q8NGT0
FLDLCYTTSSIPQLL	OR2J3	71	O76001
TPFLVALCTFAVYVT	ABCC1	556	P33527
FFITSLIYPAICTNI	SLC29A3	316	Q9BZD2
TYLDTLFCLTSIFHL	TAAR5	111	O14804
RLDPFTLYTLTLEAC	USH2A	4121	O75445
TTTLFLYFACLLPTI	SLC4A11	361	Q8NBS3
TCVLEYATPLQTLFA	STING1	256	Q86WV6
FDYFLTDLKCSLPAT	TIGAR	206	Q9NQ88
FLTTDLTYRCFVSFP	TMEM126A	76	Q9H061
ALAPTFLIYCSLRFL	SLC22A9	191	Q8IVM8
SLSFLDFCYSSTVVP	OR5AU1	116	Q8NGC0
FNLLSCTLTILISYF	OR5AU1	256	Q8NGC0
LPLFTSLLNTVCAYD	HID1	246	Q8IV36
CTFIELQDSYLLPIS	SEMA4A	151	Q9H3S1
CVFLAPLFSSFTTIV	STT3A	116	P46977
SLLSFYFPFCLLAKT	SLC41A3	491	Q96GZ6
LLSLSSAAEPSILCY	MYCBP2	3351	O75592
FTATCVPRFLYSIST	OR6C68	71	A6NDL8
SFITPLVLYCVLAAT	PLPPR1	66	Q8TBJ4
AIPYLYCTFISLLVT	OR8K3	146	Q8NH51
ITDLYLFSCIISFSS	ABCA8	221	O94911
SFIKICFPFSSSIVL	nan	46	Q8IZM0
VYLTLYNICFTSLPI	ATP11B	911	Q9Y2G3
YNICFTSLPILIYSL	ATP11B	916	Q9Y2G3
ICFTSLPILAYSLLE	ATP11C	916	Q8NB49
PFTEFVRYISTTALC	USP53	176	Q70EK8
LDPTALASFLYFTAL	TMEM237	306	Q96Q45
SSLICSFLSRIFYFP	TRIM77	426	I1YAP6
TSTFPLENVLSIFLY	TNFSF8	216	P32971
FLPLLEFAYTSVLSF	ZBTB11	266	O95625
APAYFLCISLVTFVL	ZDHHC22	11	Q8N966
LCVSVYVSLSLSSFP	LINC00052	56	Q96N35
YVSLSLSSFPCFSLT	LINC00052	61	Q96N35
SRDFTPLLCDFYTAL	NXNL2	41	Q5VZ03
LALLFYSTVLCTPHF	PIK3R5	81	Q8WYR1
LISSSYDISFCLLSL	SLCO4C1	146	Q6ZQN7
LCTIFLVAVPLYSDT	SLC7A7	426	Q9UM01
STASLCFYSLLLPIT	PIGY	36	Q3MUY2
CVLTNVSALFPFVTY	XPO5	551	Q9HAV4
FLPYLVFSILATHCT	UBIAD1	266	Q9Y5Z9
LLSFTSAFYILSIIC	SERINC3	206	Q13530
PSLCLLILDSLSAFY	XRCC2	141	O43543
SSSCNPLLIYYFTIL	ZACN	286	Q401N2
PICTYVFSLLVAFTT	SLC30A4	306	O14863
STATFYFLLPSCLFA	WDR93	351	Q6P2C0
LSFPFSIIFSTVLYC	XKR3	31	Q5GH77
SSLFPYVVLACFLVR	SLC6A17	256	Q9H1V8
DAVTLLYATSLPSFC	SLC35E4	216	Q6ICL7
AALLNIPFVYSLCFT	UGT2B28	161	Q9BY64
RLFTVYCSALFVLPL	TMEM33	31	P57088
ACYFLTDLVTFTLPA	ZRANB1	371	Q9UGI0
LGQSIFYTTTCLLPF	UNC79	151	Q9P2D8
FYTTTCLLPFLNDDI	UNC79	156	Q9P2D8
TTALFTCYISSLFTP	NLRP14	396	Q86W24