Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaminobutyraldehyde dehydrogenase (NAD+) activity

ALDH1A1 ALDH9A1

1.67e-052822GO:0019145
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring compression resistance

HSPG2 VCAN PRG4

1.11e-0423823GO:0030021
GeneOntologyCellularComponentGolgi lumen

HSPG2 VCAN MUC16 PPIL2 MUC5B MUC6

5.86e-06109866GO:0005796
DomainDUSP

USP4 USP33

2.82e-046822SM00695
DomainDUSP

USP4 USP33

2.82e-046822PF06337
Domain-

USP4 USP33

3.94e-0478223.30.2230.10
DomainDUSP

USP4 USP33

3.94e-047822PS51283
DomainPept_C19_DUSP

USP4 USP33

3.94e-047822IPR006615
DomainClathrin_a/b/g-adaptin_app_Ig

GGA2 AP2A2

6.72e-049822IPR008152
DomainAlpha_adaptinC2

GGA2 AP2A2

6.72e-049822PF02883
DomainAlpha_adaptinC2

GGA2 AP2A2

6.72e-049822SM00809
DomainTIL

MUC5B MUC6

1.22e-0312822PF01826
DomainCoatomer/clathrin_app_Ig-like

GGA2 AP2A2

1.22e-0312822IPR013041
DomainC8

MUC5B MUC6

1.22e-0312822PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC6

1.44e-0313822IPR014853
DomainC8

MUC5B MUC6

1.44e-0313822SM00832
DomainSushi

VCAN CSMD2 CSMD3

1.54e-0352823PF00084
DomainSEA

HSPG2 MUC16

1.67e-0314822SM00200
DomainTIL_dom

MUC5B MUC6

1.67e-0314822IPR002919
DomainCCP

VCAN CSMD2 CSMD3

1.72e-0354823SM00032
DomainSUSHI

VCAN CSMD2 CSMD3

1.91e-0356823PS50923
DomainSushi_SCR_CCP_dom

VCAN CSMD2 CSMD3

2.01e-0357823IPR000436
DomainVWD

MUC5B MUC6

2.20e-0316822SM00216
DomainVWF_type-D

MUC5B MUC6

2.20e-0316822IPR001846
DomainVWFD

MUC5B MUC6

2.20e-0316822PS51233
DomainAld_DH_CS_GLU

ALDH1A1 ALDH9A1

2.20e-0316822IPR029510
DomainVWD

MUC5B MUC6

2.20e-0316822PF00094
DomainAld_DH_CS_CYS

ALDH1A1 ALDH9A1

2.48e-0317822IPR016160
DomainRhoGAP

ARAP3 INPP5B CHN1

2.56e-0362823SM00324
DomainRhoGAP

ARAP3 INPP5B CHN1

2.68e-0363823PF00620
DomainALDEHYDE_DEHYDR_GLU

ALDH1A1 ALDH9A1

2.78e-0318822PS00687
DomainALDEHYDE_DEHYDR_CYS

ALDH1A1 ALDH9A1

2.78e-0318822PS00070
DomainRHOGAP

ARAP3 INPP5B CHN1

2.80e-0364823PS50238
DomainRhoGAP_dom

ARAP3 INPP5B CHN1

2.80e-0364823IPR000198
Domain-

ARAP3 INPP5B CHN1

2.80e-03648231.10.555.10
DomainVWC_out

MUC5B MUC6

3.10e-0319822SM00215
DomainAld_DH_C

ALDH1A1 ALDH9A1

3.10e-0319822IPR016163
DomainAld_DH_N

ALDH1A1 ALDH9A1

3.10e-0319822IPR016162
DomainAld_DH/histidinol_DH

ALDH1A1 ALDH9A1

3.10e-0319822IPR016161
Domain-

ALDH1A1 ALDH9A1

3.10e-03198223.40.605.10
DomainAldedh

ALDH1A1 ALDH9A1

3.10e-0319822PF00171
DomainAldehyde_DH_dom

ALDH1A1 ALDH9A1

3.10e-0319822IPR015590
Domain-

ALDH1A1 ALDH9A1

3.10e-03198223.40.309.10
DomainSEA

HSPG2 MUC16

4.15e-0322822PF01390
DomainCT

MUC5B MUC6

4.15e-0322822SM00041
DomainSEA

HSPG2 MUC16

4.54e-0323822PS50024
DomainSEA_dom

HSPG2 MUC16

4.54e-0323822IPR000082
DomainCys_knot_C

MUC5B MUC6

5.35e-0325822IPR006207
DomainCTCK_2

MUC5B MUC6

5.35e-0325822PS01225
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

POMT2 HSPG2 VCAN MUC16 MUC5B MUC6 PGM1

5.52e-06143687M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

POMT2 HSPG2 CSF2RA VCAN MUC16 MUC5B MUC6 PGM1

2.58e-05250688M27554
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC6

5.75e-0516683M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC6

6.96e-0517683M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC6

1.34e-0421683MM15706
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC6

1.77e-0423683M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC6

2.58e-0426683M27483
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

POMT2 MUC16 MUC5B MUC6

3.20e-0468684M27303
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRB3 AP2A2 ALDH9A1

4.38e-0431683M39369
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC6

2.90e-07686319110483
Pubmed

Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease.

MME IDE

6.04e-06286219019493
Pubmed

Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

MME IDE

6.04e-06286219606063
Pubmed

Combined risk effects of IDE and NEP gene variants on Alzheimer disease.

MME IDE

6.04e-06286219864659
Pubmed

[Association of single nucleotide polymorphisms of CSPG2 and HSPG2 genes with intracranial aneurysm in ethnic Han Chinese population].

HSPG2 VCAN

6.04e-06286223568740
Pubmed

Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors.

HOXA11 MME

6.04e-06286234844098
Pubmed

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene.

AP2A2 MUC6

6.04e-06286231748784
Pubmed

The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm.

HSPG2 VCAN

6.04e-06286220053631
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GABRB3 FAU AP2A2 RNPEP IGHV1-69 VCAN TMOD3 USP4 DLST SAMM50 PGM1 SEC23A PDXK IGHV1-69D

1.06e-051431861437142655
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC6

1.16e-051886318834073
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD3

1.81e-05386212906867
Pubmed

Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.

HSPG2 VCAN

1.81e-05386219669783
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

1.81e-05386227230679
Pubmed

Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.

MME IDE

1.81e-05386220663017
Pubmed

Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin.

MME IDE

1.81e-05386218602473
Pubmed

The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage.

FANCG CYP2E1

1.81e-05386211756225
Pubmed

Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells.

CCNE2 SAMHD1

1.81e-05386229782647
Pubmed

Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.

ASCL1 CCNE2 VCAN IDE

2.66e-056986421491542
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC6

3.61e-05486217471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC6

3.61e-05486214984930
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC6

3.61e-05486229869461
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC6

3.61e-05486221596555
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC6

3.61e-05486223807779
Pubmed

Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.

HSPG2 VCAN

3.61e-05486219506372
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC6

3.61e-05486212676567
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

HSPG2 RNPEP PSMB1 CDHR5 SAMM50 MME ALDH1A1 ALDH9A1 PADI2 PGM1 PDXK

4.15e-051016861119056867
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC5B MUC6

6.01e-05586224840470
Pubmed

Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?

MME MUC6

6.01e-05586222261707
Pubmed

Differential expression of glycosaminoglycans and proteoglycans in the migratory pathway of the primordial germ cells of the mouse.

HSPG2 VCAN

9.01e-05686212122449
Pubmed

Immunohistochemical distinction of renal cell carcinoma from other carcinomas with clear-cell histomorphology: utility of CD10 and CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin.

MUC16 MME

9.01e-05686225279712
Pubmed

Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).

HSPG2 VCAN

9.01e-0568629486530
Pubmed

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.

HSPG2 GJA5 VCAN

1.16e-043886329743679
Pubmed

Heterochronic misexpression of Ascl1 in the Atoh7 retinal cell lineage blocks cell cycle exit.

ASCL1 OPN1SW

1.26e-04786223481413
Pubmed

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.

HSPG2 VCAN

1.26e-04786237174615
Pubmed

ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles.

GABRB3 CYP2E1

1.26e-04786215318112
Pubmed

Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.

HOXA11 PRG4

1.68e-04886220978074
Pubmed

Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development.

GJA5 VCAN

1.68e-04886216530167
Pubmed

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments.

IGHV1-69 IGHV1-69D

2.15e-0498622578321
Pubmed

Germline diversity of the expressed BALB/c VhJ558 gene family.

IGHV1-69 IGHV1-69D

2.15e-04986211483206
Pubmed

SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes.

HOXA11 GJA5

2.15e-04986218470945
Pubmed

Diversity of germ-line immunoglobulin VH genes.

IGHV1-69 IGHV1-69D

2.15e-0498626789211
Pubmed

Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury.

CYP2E1 ALDH1A1

2.15e-04986227746183
Pubmed

The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner.

ARAP3 SAMHD1

2.68e-041086217314030
Pubmed

Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye.

ALDH1A1 OPN1SW

2.68e-041086221148184
Pubmed

Combinatorial association of V genes: one VH gene codes for three non-cross-reactive monoclonal antibodies each specific for a different antigen (phoxazolone, NP or gat).

IGHV1-69 IGHV1-69D

2.68e-04108623211160
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

ATP11B IDE R3HDM1 TDP1 ERN2 CHN1 PADI2 NUDT13

3.02e-0468686829987050
Pubmed

Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

FANCG CYP2E1 PSMB1

3.13e-045386314499622
Pubmed

Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development.

POMT2 HSPG2

3.93e-041286221452199
Pubmed

Card9 protects fungal peritonitis through regulating Malt1-mediated activation of autophagy in macrophage.

AP2A2 PDXK

3.93e-041286235850054
Pubmed

Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.

ASCL1 ALDH1A1

4.63e-041386216438966
Pubmed

Genome-wide association study of panic disorder in the Japanese population.

SDK2 GRM7

4.63e-041386219165232
Pubmed

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.

HSPG2 DLST SAMM50 PGM1

4.97e-0414786426465331
Pubmed

Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells.

DLST MME SEC23A

5.21e-046386317220478
Pubmed

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.

ASCL1 MUC5B

5.39e-041486222797898
Pubmed

Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.

HOXA11 PRG4

5.39e-041486224154528
Pubmed

Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.

MME IDE

6.21e-04158621460423
Pubmed

Tie2 regulates endocardial sprouting and myocardial trabeculation.

HSPG2 ARAP3 VCAN

6.51e-046886331112136
Pubmed

The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome.

USP4 PGM1

7.09e-041686223022198
Pubmed

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

HSPG2 IDE

7.09e-041686219889475
Pubmed

Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.

GJA5 LGR6

7.09e-041686229859889
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

AP2A2 RNPEP PSMB1 DUOX2 DLST SAMHD1 SAMM50 IDE SEC23A PDXK MGAM2

7.68e-041425861130948266
Pubmed

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.

IGHV1-69 IGHV1-69D

9.01e-04188626788376
Pubmed

Functional screen identifies regulators of murine hematopoietic stem cell repopulation.

ZNF251 ARMCX1

9.01e-041886226880577
Pubmed

Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.

GJA5 ALDH1A1

1.01e-031986220185795
Pubmed

Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.

AP2A2 CCNE2

1.01e-031986215799026
Pubmed

beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region.

ASCL1 ALDH1A1

1.12e-032086220532162
Pubmed

Fzd3 and Fzd6 deficiency results in a severe midbrain morphogenesis defect.

ASCL1 ALDH1A1

1.23e-032186219842188
Pubmed

Brain transcriptome-wide screen for HIV-1 Nef protein interaction partners reveals various membrane-associated proteins.

VKORC1L1 CHN1

1.23e-032186223284715
Pubmed

Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.

GJA5 CCNE2

1.35e-032286238014633
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

CSF2RA TULP4 CSMD2 PRG4 SNX12

1.37e-0332986517474147
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

HSPG2 VCAN

1.48e-032386230814516
Pubmed

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.

ALDH1A1 ALDH9A1

1.48e-032386218971422
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

VKORC1L1 TMOD3 SAMM50 SEC23A USP33 SLC30A6

1.59e-0350486634432599
Pubmed

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.

ALDH1A1 LGR6

1.61e-032486231772170
Pubmed

Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis.

ASCL1 CCNE2

1.61e-032486220808958
Pubmed

Fibroblast growth factor 2 regulates dopaminergic neuron development in vivo.

ASCL1 ALDH1A1

1.61e-032486222537018
Pubmed

Human immunodeficiency virus type-1 gag and host vesicular trafficking pathways.

GGA2 AP2A2

1.61e-032486220012524
Pubmed

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.

HSPG2 ALDH1A1 SEC23A

1.61e-039386338245532
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

HSPG2 VCAN PRG4

1.82e-039786327559042
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FAU ARAP3 AP2A2 PSMB1 TUBGCP3 DLST SAMM50 ALDH9A1 ARMCX1 SEC23A

1.86e-031353861029467282
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

SFXN5 RAB24 DLST SAMM50 IDE ALDH9A1 NUDT13 SLC30A6

2.09e-0392686820877624
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ATP11B PADI2 SBNO2

2.10e-0310286310231032
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LOXHD1 BRME1 SAMHD1 CSMD2 CHN1 PRG4 PGM1

2.34e-0373686729676528
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

ATP11B ASCL1 ATP13A5 MME PADI2

2.45e-0337686524154525
Cytoband11p15.5

AP2A2 CDHR5 MUC5B MUC6

8.19e-0511888411p15.5
Cytoband16p12

GGA2 RRN3

3.26e-041488216p12
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC6

4.21e-0521593648
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

VCAN CSMD2 CSMD3

8.52e-04575931179
GeneFamilyAldehyde dehydrogenases

ALDH1A1 ALDH9A1

1.73e-0319592398
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GGA2 RNPEP OASL AOC3 SAMHD1 MME

1.46e-061788860b398656f26c4061b11ccf98908d0e2e1367585a
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZPLD1 MUC16 ATP13A5 MUC5B ALDH1A1 ERN2

2.00e-0618888607705bed928683470a52c8ccfa40ffb9a0971318
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2E1 ZPLD1 MUC16 MUC5B ERN2 PADI2

2.70e-061988861fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 GJA5 ARAP3 CRYBG3 CHN1

1.97e-051668858e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GJA5 FAM187B OASL MUC6

2.13e-0582884ea3bdd7b871269eacb81167c6cf59a0e21bf6d83
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GJA5 FAM187B OASL MUC6

2.13e-058288472d5a55ca7c03e9c54f865524e206b288f242017
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GJA5 FAM187B OASL MUC6

2.13e-0582884e500582511814a067852dc3bd78d19937c28ba60
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA11 COL27A1 VCAN TMOD3 CSMD3

2.21e-05170885b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCelldroplet-Fat-Scat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA AP2A2 RNPEP VCAN PRG4

2.34e-051728858a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

MUC16 ATP13A5 MUC5B ALDH1A1 LGR6

2.47e-05174885ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

MUC16 ATP13A5 MUC5B ALDH1A1 LGR6

2.61e-05176885cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

MUC16 ATP13A5 MUC5B MME ERN2

2.75e-05178885fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

MUC16 ATP13A5 MUC5B MME ERN2

2.75e-05178885b19c906e067b07eadfd68934d9330b447e24c708
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 DUOX2 MUC5B ERN2 MGAM2

2.83e-05179885859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 DUOX2 MUC5B ERN2 MGAM2

2.90e-051808853dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 DUOX2 MUC5B ERN2 MGAM2

2.90e-05180885668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASCL1 MUC5B ALDH1A1 ERN2 GRM7

2.98e-05181885092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 DUOX2 MUC5B ERN2 MGAM2

3.14e-0518388515d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 GJA5 ARAP3 CRYBG3 FAM124B

3.48e-05187885d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 GJA5 ARAP3 CRYBG3 CHN1

3.66e-051898856463890d8dbee4bc198f91628a5f784970de786a
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

GGA2 OASL AOC3 MME ALDH1A1

3.76e-051908852592765016f291565697265800a232b2edef3792
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

GGA2 OASL AOC3 MME ALDH1A1

3.76e-051908859fc763d65470ba8858b973689c4d4358faab7dd3
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POMT2 MUC16 DUOX2 ALDH1A1 ERN2

3.76e-051908852fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LOXHD1 ARAP3 MME CSMD3 PADI2

3.85e-05191885d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 GJA5 ARAP3 FAM124B CHN1

3.85e-051918854b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VKORC1L1 OASL AOC3 MME ALDH1A1

4.05e-05193885aa679fb27f914a931e51cff7153861cde0edfd85
ToppCellwk_20-22-Hematologic-Myeloid-DC1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CSF2RA CYP2E1 SAMHD1 NLRP4 MGAM2

4.05e-05193885a260d943e9db966e4ce7d642313fd11354c2d2ba
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GJA5 SDK2 VCAN AOC3 CSMD3

4.15e-05194885011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellMonocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CSF2RA AP2A2 SIRPB2 SAMHD1 ALDH1A1

4.15e-051948853e104e85574894c04791252d466d438fc809dde3
ToppCell3'-Distal_airway-Immune_Myeloid|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RA OASL AOC3 SAMHD1 MME

4.25e-051958854df004b8ca7669a57d85c6dffef5b82b4ea1dfdf
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HSPG2 MUC16 DUOX2 MUC5B ERN2

4.25e-05195885b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCell3'-Airway_Nasal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DUOX2 ATP13A5 ALDH1A1 ERN2

4.25e-051958857ffbdbe95b248699bf6300322d084d21a4a4b1b8
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GJA5 SDK2 AOC3 ALDH9A1 PRG4

4.36e-051968856730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GJA5 SDK2 AOC3 ALDH9A1 PRG4

4.36e-0519688521dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

VKORC1L1 OASL AOC3 MME ALDH1A1

4.36e-05196885fe90501010128b72e6711c567cb04b012f1520a4
ToppCell3'-Airway_Nasal-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DUOX2 ATP13A5 ALDH1A1 ERN2

4.36e-05196885eadc3e60104214cb5f6cfb098a5c5ea0f83d15bd
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FNDC1 COL27A1 VCAN CHN1 PGM1

4.57e-05198885c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CSF2RA OASL SIRPB2 SAMHD1 MME

4.57e-05198885e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CSF2RA OASL SIRPB2 SAMHD1 MME

4.57e-051988850baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DUOX2 MUC5B ALDH1A1 ERN2

4.57e-05198885484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FNDC1 COL27A1 VCAN CHN1 PGM1

4.57e-051988853e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 VCAN CSMD2 CSMD3 GRM7

4.68e-05199885333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellControl-Control-Others-HSPC|Control / Disease, condition lineage and cell class

HSPG2 MME ALDH1A1 FAM124B ARMCX1

4.68e-05199885b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCellCaecum-(5)_Dendritic_cell-(51)_cDC1|Caecum / shred on region, Cell_type, and subtype

CSF2RA CYP2E1 SIRPB2 CRYBG3 FAM124B

4.68e-051998852b97fda45241b2ce7be904cf081cabcf3eb5ba1d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 VCAN CSMD2 CSMD3 GRM7

4.68e-0519988519a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 VCAN CSMD2 CSMD3 GRM7

4.68e-05199885e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellCaecum-Dendritic_cell-cDC1|Caecum / Region, Cell class and subclass

CSF2RA CYP2E1 SIRPB2 CRYBG3 FAM124B

4.68e-051998859ab38a0060a883de6fe3da8cdac42e124d7981d9
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CSF2RA OASL SIRPB2 SAMHD1 MME

4.79e-05200885a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CSF2RA RNPEP VCAN SIRPB2 ALDH1A1

4.79e-05200885107a0665fb20247511a430178effd7630a619488
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RAB24 VCAN SIRPB2 SAMHD1 PADI2

4.79e-0520088507197f95282ee607db17b92fea1376051e65fc50
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CSF2RA OASL SIRPB2 SAMHD1 MME

4.79e-05200885ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SFXN5 CSF2RA RNPEP VCAN PDXK

4.79e-052008859e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B ERN2 PADI2 MGAM2

4.79e-0520088585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 DUOX2 MUC5B ZNF251

6.27e-051088849c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 DUOX2 MUC5B ZNF251

6.27e-0510888475d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cdkn2b_(Cdkn2b)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GJA5 CYP2E1 OASL FAM124B

9.14e-05119884a3807e738d7ca8cf80aa4bd35e3ee4357b1dc00f
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cdkn2b_(Cdkn2b)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

GJA5 CYP2E1 OASL FAM124B

9.14e-051198848a3f0a3ed9f80d7b061162e9fa519bb09804a86c
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cdkn2b_(Cdkn2b)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GJA5 CYP2E1 OASL FAM124B

9.14e-05119884938da0fe90372709048bf4e5503cc1cbf8376b17
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GJA5 FAM187B ARAP3 OASL

1.36e-0413288406e7337de35bd7120655a22b6020604ad004c4e1
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GJA5 FAM187B OASL FAM124B

1.40e-04133884bc29a2faa151b0e48c1c7e3f016cccc49f9a15eb
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CCSER2 MUC16 LGR6 ZNF251

1.53e-041368849d7080f695de4ef183e3dbdc18ba464a3b8e3469
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MUC16 TEX15 CSMD3 GRM7

1.66e-0413988464c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

GABRB3 KCNMB1 LGR6 MUC6

1.71e-041408845623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GABRB3 KCNMB1 DUOX2 SAMHD1

1.71e-04140884c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP2E1 KCNMB1 PADI2 MGAM2

1.96e-04145884f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Lepidic_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

DUOX2 CDHR5 ERN2 MUC6

2.28e-041518843dfa1d89975ffaa45b26833538244153d50c60a7
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Lepidic_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

DUOX2 CDHR5 ERN2 MUC6

2.28e-0415188460bb6de5d9b13402bc18cb6d5e51078326dff8e2
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B ALDH1A1 ERN2 MUC6

2.52e-041558848dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MUC5B ALDH1A1 ERN2 MUC6

2.52e-0415588442533beaded07068f00540de704de07e4f19abcf
ToppCellfacs-Lung-EPCAM-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNPEP OASL SAMHD1 PADI2

2.71e-04158884ef5feb48161c339c7b71c576bdda61479d29dfac
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNPEP OASL SAMHD1 PADI2

2.71e-04158884c6e64b9b3342e37d54baadae8fb7dfb5d246e4cf
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 CHN1 CSMD3 ZNF251

2.71e-041588846d2709b387945c015faa223c20d22b52a4082140
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2E1 VCAN KCNMB1 LGR6

2.85e-041608848624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2E1 VCAN KCNMB1 LGR6

2.85e-041608849de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXA11 FNDC1 VCAN ARMCX1

2.92e-04161884a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CSF2RA PADI2 NLRP4 MGAM2

2.92e-04161884cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXA11 FNDC1 VCAN ARMCX1

2.92e-0416188408920a716f6ec62538e361211455a30ad726d7be
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DUOX2 ATP13A5 LGR6 CSMD3

2.98e-04162884bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HOXA11 TMEM217 ZPLD1 AOC3

3.20e-04165884cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

VKORC1L1 MME PDXK PLAAT5

3.27e-041668847e5852891714465c6228c9f955fd511ec79d0e02
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 MME CSMD2 CSMD3

3.35e-041678843edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB1 FAM124B CHN1 CSMD3

3.35e-04167884e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RA MUC5B PRG4 NUDT13

3.35e-04167884589c0acfeb4d70931b6726fb3331d85a54e74d56
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNE2 AOC3 KCNMB1 CHN1

3.35e-04167884b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CSF2RA KCNMB1 SIRPB2 SAMHD1

3.50e-04169884b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP11B MUC5B ERN2 PADI2

3.50e-04169884f2e20049a17eee533d49bd5f24a51962d123d132
ToppCellfacs-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA RNPEP VCAN SAMHD1

3.50e-0416988405b138511039f1255a5f647040b1b9bdf222bd52
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DUOX2 MUC5B MUC6 PLAAT5

3.50e-04169884a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

GGA2 COL27A1 OASL LGR6

3.50e-0416988417568e7aacfdcd96c469bae57d5ffad04954e9bd
ToppCellfacs-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA RNPEP VCAN SAMHD1

3.50e-04169884bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP11B MUC5B ERN2 PADI2

3.50e-041698844c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CSF2RA KCNMB1 SIRPB2 SAMHD1

3.50e-041698842322f03a115c662f808ebfc892192b7d38d48181
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSF2RA CYP2E1 SAMHD1 NLRP4

3.50e-041698844de0c60f3c163b7823f739ebda4e0afc68346628
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA AP2A2 RNPEP VCAN

3.58e-04170884de722bea7527d6ad11b69f8e9589638f52854beb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HSPG2 FNDC1 ALDH1A1 NLRP4

3.58e-041708847d736e741799b67a7f022fc6766841c951ef8951
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 GJA5 CCSER2 ARMCX1

3.58e-0417088455fe16d98ea284d05fb899888e4569c685644c7b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HSPG2 FNDC1 ALDH1A1 NLRP4

3.58e-04170884489fc97f6002a577b882a8ff3c563b1e42041d38
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

LOXHD1 CSF2RA KCNMB1 SAMHD1

3.58e-04170884403b6b749d70d845838dcda7daf99971b50792a2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FANCG SFXN5 OASL FAM124B

3.58e-04170884f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

VCAN CDHR5 SAMHD1 PADI2

3.58e-041708844e93b66b3033e6e4d5f6d2f41974623a53108f5e
DrugBetazole hydrochloride; Down 200; 27uM; PC3; HT_HG-U133A

POMT2 VCAN PPIL2 ERN2 NUDT13 SEC23A SBNO2

7.52e-061968376344_DN
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; MCF7; HT_HG-U133A

GGA2 AP2A2 CCSER2 PPIL2 MUC5B ARMCX1 SEC23A

7.77e-061978377101_DN
DrugNaloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HG-U133A

HSPG2 CYP2E1 PPIL2 SAMHD1 ERN2 SEC23A SBNO2

8.03e-061988371924_UP
DrugRitodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A

GGA2 CCNE2 VCAN CCSER2 OASL SEC23A

5.44e-051828361280_UP
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A

POMT2 GGA2 AP2A2 INPP5B VCAN SEC23A

6.91e-051908366718_DN
DrugEthopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; MCF7; HT_HG-U133A

POMT2 GGA2 RRN3 OASL ERN2 SEC23A

7.12e-051918365296_UP
DrugCinoxacin [28657-80-9]; Down 200; 15.2uM; HL60; HT_HG-U133A

CCNE2 VCAN PSMB1 OASL PADI2 SEC23A

7.32e-051928362722_DN
DrugCP-320650-01 [172079-28-6]; Down 200; 1uM; MCF7; HT_HG-U133A

HSPG2 RRN3 INPP5B PPIL2 NPHP4 PDXK

7.54e-051938363908_DN
Drugcarbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

AP2A2 CCNE2 OASL PPIL2 PDXK SBNO2

7.54e-05193836835_DN
Drug1'-hydroxymethyleugenol

CYP2E1 AOC3

7.84e-054832CID000198104
Drugsodium 4-phenylbutyrate; Down 200; 1000uM; PC3; HG-U133A

HSPG2 ASCL1 CCSER2 PPIL2 MUC5B ERN2

7.98e-05195836434_DN
DrugBoldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

GGA2 AP2A2 CYP2E1 PPIL2 R3HDM1 SBNO2

8.21e-051968364122_DN
DrugDelcorine; Up 200; 8.4uM; PC3; HT_HG-U133A

VCAN OASL KCNMB1 OPN1SW ERN2 PADI2

8.21e-051968364275_UP
DrugSulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A

HSPG2 VCAN PSMB1 DUOX2 MUC5B MUC6

8.44e-051978366099_UP
DrugAndrosterone [53-41-8]; Up 200; 13.8uM; PC3; HT_HG-U133A

HSPG2 GGA2 AP2A2 RRN3 VCAN TEX15

8.44e-051978364635_UP
Drugdexamethasone; Up 200; 1uM; MCF7; HG-U133A

ATP11B SAMHD1 ERN2 NPHP4 PADI2 SBNO2

8.44e-05197836255_UP
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; HL60; HT_HG-U133A

HSPG2 GGA2 PSMB1 R3HDM1 PADI2 SBNO2

8.44e-051978362172_DN
DrugMoxonidine [75438-57-2]; Down 200; 16.6uM; PC3; HT_HG-U133A

GGA2 PSMB1 PPIL2 R3HDM1 ERN2 SBNO2

8.44e-051978364084_DN
DrugProglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A

HSPG2 GGA2 VCAN MUC5B SEC23A SBNO2

8.44e-051978364337_DN
DrugChlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A

HOXA11 ASCL1 VCAN R3HDM1 ERN2 GRM7

8.68e-051988364345_UP
DrugAG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A

GGA2 AP2A2 INPP5B FAM124B ERN2 GRM7

8.68e-051988365944_DN
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A

POMT2 GGA2 AP2A2 TUBGCP3 CCSER2 TMOD3

8.68e-051988362100_DN
DrugMonocrotaline [315-22-0]; Up 200; 12.2uM; PC3; HT_HG-U133A

HOXA11 GGA2 ARAP3 INPP5B VCAN OASL

8.68e-051988367127_UP
DrugSulfamethoxazole [723-46-6]; Down 200; 15.8uM; PC3; HT_HG-U133A

HSPG2 GGA2 ARAP3 ERN2 NPHP4 SBNO2

8.68e-051988367366_DN
DrugNomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A

POMT2 GGA2 VCAN PPIL2 NUDT13 SBNO2

8.68e-051988366362_DN
DrugArecoline hydrobromide [300-08-3]; Down 200; 17uM; MCF7; HT_HG-U133A

GGA2 INPP5B PPIL2 ERN2 NUDT13 SBNO2

8.92e-051998365423_DN
DrugTolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; PC3; HT_HG-U133A

HSPG2 CYP2E1 ASCL1 PSMB1 PPIL2 MME

8.92e-051998364262_UP
DrugYohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; HL60; HT_HG-U133A

HOXA11 HSPG2 AP2A2 CCSER2 KCNMB1 PPIL2

8.92e-051998362147_DN
DrugAH6809; Down 200; 1uM; PC3; HT_HG-U133A

POMT2 RRN3 VCAN TMOD3 PPIL2 SBNO2

8.92e-051998367075_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A

HSPG2 GGA2 INPP5B OASL DUOX2 ERN2

9.17e-052008362077_UP
Drugindomethacin, USP; Up 200; 100uM; MCF7; HG-U133A

HOXA11 CYP2E1 ASCL1 USP4 SAMHD1 ERN2

9.17e-05200836453_UP
Diseasecerebral amyloid angiopathy (is_marker_for)

AOC3 MME

4.90e-054852DOID:9246 (is_marker_for)
DiseaseTourette syndrome

COL27A1 MUC16 CSMD3

4.10e-0450853EFO_0004895
Diseasehypertension (implicated_via_orthology)

GJA5 RNPEP KCNMB1 MME

5.21e-04128854DOID:10763 (implicated_via_orthology)
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC6

8.47e-0464853DOID:4947 (is_marker_for)
Diseaseanorectal malformation

MUC5B CSMD2

1.36e-0319852MONDO_0019938
DiseaseHodgkins lymphoma

BRME1 ATP13A5 OPN1SW

1.73e-0382853EFO_0000183
Diseasesystemic scleroderma

TULP4 CDHR5 GRM7

1.92e-0385853EFO_0000717

Protein segments in the cluster

PeptideGeneStartEntry
FVVSQPLNYRGGARV

ALDH9A1

6

P49189
KNFPQELRSYTVQGF

ATP13A5

641

Q4VNC0
KLSPQGNYVFQRRFV

ARAP3

296

Q8WWN8
VYTQGQAVLNRAFFP

RNPEP

166

Q9H4A4
PISAGLYGNFTAQVR

CSMD2

1001

Q7Z408
LLGSYNGTQVPQFLF

CSMD3

961

Q7Z407
GVRTLYRFENQTGFP

VCAN

321

P13611
GGIFQEPVSKYFRVQ

CRYBG3

2256

Q68DQ2
NYINTFRKGGQLSPV

CCNE2

371

O96020
QGRTIPIDGNFFTYT

ALDH1A1

141

P00352
GNKGYFVQPTVFSNV

ALDH1A1

376

P00352
PIIYSIFRGNVNGTF

CDHR5

286

Q9HBB8
FRYGGTFQNVSVQLP

AP2A2

806

O94973
FYPQGPRFSVQGSRV

AOC3

316

Q16853
SVTFNGQVFQARLPY

MUC5B

5196

Q9HC84
NIFSIPYFQQTGVRG

PGM1

316

P36871
QFSRPFVPGQGDSRY

R3HDM1

916

Q15032
RFLVGPYQNTIGAAF

RAB24

31

Q969Q5
QGPQTFRQGVGKYIN

PPIL2

471

Q13356
SYVTSPQGFQFRRLG

HSPG2

176

P98160
AQRFGPVFTLYVGSQ

CYP2E1

61

P05181
GNETSVLFQRLYGPQ

KCNMB1

141

Q16558
NASLFGLTRIPYFQN

OOSP3

151

A0A2R8YFM6
LFINGYAPQNLSIRG

MUC16

14186

Q8WXI7
QAYVTVGPQFRGQTR

MUC6

516

Q6W4X9
ISGNETQYLPFIRGQ

MGAM2

1276

Q2M2H8
NPIQFVGRSAFQYLP

LGR6

291

Q9HBX8
IPIFGTANYAQKFQG

IGHV1-69

71

P01742
LGQVPDGFVQYFTNR

ERN2

871

Q76MJ5
TNSPIFIQIYGQKGR

LOXHD1

441

Q8IVV2
PSGVTYLQFQRPQGF

DUOX2

1281

Q9NRD8
YSSGRNQIVFPAGIL

MME

546

P08473
RLRYKLTFNQGGQPF

GGA2

581

Q9UJY4
QFQYAVRVIGSNFAP

TUBGCP3

31

Q96CW5
FVNYIFFGRGPQRQK

GABRB3

326

P28472
RGNPQGQVDSLAIFY

NLRP4

541

Q96MN2
FAYRQGLQELITGNP

FANCG

211

O15287
FYSTVGRNGVLPQAF

HOXA11

126

P31270
KVGVFYVENPFFGQR

PADI2

211

Q9Y2J8
IPIFGTANYAQKFQG

IGHV1-69D

71

A0A0B4J2H0
RKGPYTQQQNGTFPF

NUDT13

311

Q86X67
TYTIGLQFAPSQRVG

NPHP4

1386

O75161
TRGYSGLQRLSFQVP

OASL

386

Q15646
GYPNSRKVVINNSVF

DLST

41

P36957
INTPKSQLNGFYGNR

CCSER2

166

Q9H7U1
QTYFGGFPRDLQTSQ

FAM124B

376

Q9H5Z6
QNSFGRFVPQFAKSR

BRME1

96

Q0VDD7
RRLNFSGFGYSLPQQ

ASCL1

101

P50553
QYRQEPVRFGNIGFG

FNDC1

1861

Q4ZHG4
QTPGEGFIQVRYGQK

GJA5

306

P36382
GVIPFQSGFIFTQRA

COL27A1

66

Q8IZC6
RFFAGTYNVNGQSPK

INPP5B

346

P32019
YIRNVNFNGSAGTPV

GRM7

451

Q14831
YIVFSGPRRANGIQG

IDE

831

P14735
TGGRQLQVFQPAVYK

FAM187B

271

Q17R55
QRQPGTYTLALRFGS

CHN1

76

P15882
RNFSVNLYKVTGQFP

SAMM50

186

Q9Y512
YRVQVQAFNAIGSGP

SDK2

1171

Q58EX2
LQLRFSPYVFNGGTI

PSMB1

26

P20618
SQRGFQQKLLYPNSG

CSF2RA

101

P15509
RQPLNYILVNVSFGG

OPN1SW

66

P03999
PAIIRQAAGNYIGSF

RRN3

396

Q9NYV6
NPQTVGVGRARFTTY

SNX12

36

Q9UMY4
PINYQGLRFSGVNDT

POMT2

571

Q9UKY4
RNLFKYVGETQPTGQ

SAMHD1

451

Q9Y3Z3
LGYQGQLEARQTPAF

PRR20G

111

P0DPQ3
NRGQFFTVYKPNIGR

SBNO2

1086

Q9Y2G9
PESVYFFKRGGSIQQ

PRG4

1256

Q92954
RGYVGNRAATFPLQV

PDXK

16

O00764
IPQGGRGAIQFVTQY

SEC23A

471

Q15436
YSFNQNAIRELGGVP

ARMCX1

236

Q9P291
NRFPQNGLYTPQKFI

ATP11B

26

Q9Y2G3
VSNRYSNPGQVIFGS

TULP4

746

Q9NRJ4
GNPFQFYLTRVSGVK

TDP1

161

Q9NUW8
QQEIYNFKRGSFPGV

SIRPB2

81

Q5JXA9
TIRVLPGSAQFNGYN

ZPLD1

11

Q8TCW7
KTQVGRFAPQFSGYQ

USP4

376

Q13107
SYNEQFFGPGTRLTV

TRBJ2-1

1

A0A0A0MTA7
PAIIRQAAGNYIGSF

RRN3P1

21

Q2M238
GVLNQPNSVFGLIFY

VKORC1L1

81

Q8N0U8
TQGLRTGFTNIPSRY

SLC30A6

436

Q6NXT4
AVYFSQAEGRQLGPQ

ZNF251

21

Q9BRH9
FVNGLRYGVPRSQQV

PLAAT5

236

Q96KN8
QYNRRFVNVVPTFGK

FAU

111

P62861
LGKPRGFQQQSNFYP

TEX15

1731

Q9BXT5
TPKYRGASNIINNFI

TMEM217

46

Q8N7C4
QLGKPRFQQTSFYGR

SFXN5

26

Q8TD22
GIKTVNPTFRGYSQQ

USP33

256

Q8TEY7
LKFGYQFTQQGPRTR

TMOD3

316

Q9NYL9