Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC37A1 SLC22A18 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLCO1A2 SLC5A7 SLC30A1 SLC23A1 SLC47A2

6.78e-092968812GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC37A1 SLC22A18 ABCG1 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLCO1A2 SLC22A2 SLC5A7 SLC30A1 SLC23A1 SLC47A2

2.09e-084778814GO:0022804
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC37A1 SLC22A18 SPNS1 ABCG1 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 PKD1L1 SLC5A7 SLC30A1 SVOP SLC23A1 SLC7A10 SLC47A2 RHCE RHD

2.96e-0811808821GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC37A1 SLC22A18 SPNS1 ABCG1 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 PKD1L1 SLC5A7 SLC30A1 SVOP SLC23A1 SLC7A10 SLC47A2 RHCE RHD

1.33e-0712898821GO:0005215
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC44A1 SLCO1A2 SLC22A2 SLC5A7 SLC7A10 SLC47A2

1.77e-0683886GO:0015101
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC44A1 SLC22A2 SLC5A7

4.56e-068883GO:0015220
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

1.24e-0568885GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

1.33e-0569885GO:0016278
GeneOntologyMolecularFunctionMHC protein complex binding

CD4 HLA-DMA LILRB2 HLA-DRA

3.15e-0541884GO:0023023
GeneOntologyMolecularFunctionsymporter activity

SLC22A18 SLC12A1 SLC15A1 SLC15A2 SLC5A7 SLC23A1

5.31e-05150886GO:0015293
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A1 SLC12A1 SLC15A1 SLC15A2 SLC5A7 SLC30A1 SLC23A1 SLC47A2

5.49e-05301888GO:0022853
GeneOntologyMolecularFunctionprotein methyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

9.24e-05103885GO:0008276
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC9A1 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2 RHCE RHD

9.58e-056278811GO:0022890
GeneOntologyMolecularFunctionN-methyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

1.01e-04105885GO:0008170
GeneOntologyMolecularFunctionpeptide:proton symporter activity

SLC15A1 SLC15A2

1.15e-044882GO:0015333
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC37A1 SLC9A1 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2 RHCE RHD

1.20e-047588812GO:0015318
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A1 SLC15A1 SLC15A2 SLC5A7 SLC23A1

1.82e-04119885GO:0015294
GeneOntologyMolecularFunctiondipeptide transmembrane transporter activity

SLC15A1 SLC15A2

1.90e-045882GO:0071916
GeneOntologyMolecularFunctionMHC class II protein complex binding

CD4 HLA-DMA HLA-DRA

2.24e-0427883GO:0023026
GeneOntologyMolecularFunctionantiporter activity

SLC37A1 SLC9A1 SLC44A1 SLC30A1 SLC47A2

3.63e-04138885GO:0015297
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC22A18 SLC22A2 SLC47A2

4.48e-0434883GO:0042910
GeneOntologyMolecularFunctionpeptide binding

HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGA2 ITGB2

5.13e-04318887GO:0042277
GeneOntologyMolecularFunctiontripeptide transmembrane transporter activity

SLC15A1 SLC15A2

6.78e-049882GO:0042937
GeneOntologyMolecularFunctionamine transmembrane transporter activity

SLC44A1 SLC22A2

6.78e-049882GO:0005275
GeneOntologyMolecularFunctionpeptide transmembrane transporter activity

SLC15A1 SLC15A2

6.78e-049882GO:1904680
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ERBB4 TAS2R8 ADRA1A IL31RA CD4 LILRB2 AGER HLA-DRA MRGPRE ITGA2 TNFRSF1B TREML1 ITGB2 PLXNA1 PLXNB1

7.88e-0413538815GO:0004888
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

9.85e-04172885GO:0008757
GeneOntologyMolecularFunctionamyloid-beta binding

LILRB2 AGER ITGA2 ITGB2

1.08e-03102884GO:0001540
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA1 PLXNB1

1.23e-0312882GO:0017154
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

ABCG1 SLC22A2

1.23e-0312882GO:0019534
GeneOntologyMolecularFunctionammonium channel activity

RHCE RHD

1.23e-0312882GO:0008519
GeneOntologyMolecularFunctionpeptide antigen binding

HLA-A HLA-DMA HLA-DRA

1.32e-0349883GO:0042605
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC9A1 SLC15A1 SLC15A2 SLC30A1 SLC47A2

1.46e-03188885GO:0015078
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A1 SLC22A18 SLCO1A2 SLC22A2 SLC23A1 SLC7A10

1.88e-03293886GO:0008514
GeneOntologyMolecularFunctionMHC protein binding

CD4 HLA-A LILRB2

2.14e-0358883GO:0042287
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLC15A1 SLC15A2

2.21e-0316882GO:0035673
GeneOntologyMolecularFunctionmethyltransferase activity

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

2.52e-03213885GO:0008168
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC9A1 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2

2.60e-03664889GO:0008324
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

3.13e-03224885GO:0016741
GeneOntologyMolecularFunctionT cell receptor binding

HLA-A HLA-DRA

3.46e-0320882GO:0042608
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCG1 SLC44A1 SLCO1A2

3.66e-0370883GO:1901618
GeneOntologyMolecularFunctionhistone methyltransferase activity

EEF2KMT METTL21A EEF1AKMT3

3.81e-0371883GO:0042054
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCG1 SLCO1A2 SLC22A2

4.12e-0373883GO:0170055
GeneOntologyMolecularFunctioncell adhesion mediator activity

AGER ESAM ITGA2

4.61e-0376883GO:0098631
GeneOntologyMolecularFunctioncell adhesion molecule binding

LILRB2 AGER ESAM ITGA2 VSIG10 CDH2 ITGB2 CDH15

4.91e-03599888GO:0050839
GeneOntologyMolecularFunctioncytokine binding

IL31RA CD4 AGER TNFRSF1B

5.14e-03157884GO:0019955
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC15A1 SLC15A2

5.39e-0325882GO:0015295
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC12A1 SLC5A7 SLC23A1

5.51e-0381883GO:0015370
GeneOntologyMolecularFunctionimmune receptor activity

IL31RA CD4 LILRB2 HLA-DRA

6.12e-03165884GO:0140375
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A1 SLC30A1

6.27e-0327882GO:0051139
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A7 SLC23A1

6.27e-0327882GO:0015145
GeneOntologyMolecularFunctioncargo receptor activity

AGER ITGB2 SDC1

6.30e-0385883GO:0038024
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A1 SLC12A1 SLC5A7 SLC23A1

6.93e-03171884GO:0015081
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A7 SLC23A1

7.22e-0329882GO:0051119
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC9A1 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2

8.17e-03793889GO:0015075
GeneOntologyMolecularFunctionMHC class I protein binding

HLA-A LILRB2

8.74e-0332882GO:0042288
GeneOntologyBiologicalProcessexport across plasma membrane

SLC22A18 SLC9A1 SLC15A2 SLC22A2 SLC30A1 SLC47A2

2.37e-0691876GO:0140115
GeneOntologyBiologicalProcessorganic cation transport

SLC22A18 SLC44A1 SLCO1A2 SLC22A2 SLC5A7 SLC7A10 SLC47A2

2.68e-06145877GO:0015695
GeneOntologyBiologicalProcessT cell mediated immunity

PDCD1 IL31RA HLA-A AGER HLA-DRA TNFRSF1B MUC4

5.82e-06163877GO:0002456
GeneOntologyBiologicalProcessregulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

PDCD1 CD4 HLA-A HLA-DMA AGER HLA-DRA TNFRSF1B MUC4

6.79e-06235878GO:0002822
GeneOntologyBiologicalProcesspeptidyl-lysine methylation

EEF2KMT METTL21A FAM86B2 EEF1AKMT3

7.44e-0630874GO:0018022
GeneOntologyBiologicalProcessxenobiotic transport

SLC22A18 SLC15A2 SLC22A2 SVOP SLC47A2

7.45e-0664875GO:0042908
GeneOntologyBiologicalProcessregulation of T cell mediated immunity

PDCD1 HLA-A AGER HLA-DRA TNFRSF1B MUC4

7.51e-06111876GO:0002709
GeneOntologyBiologicalProcesscholine transport

SLC44A1 SLC22A2 SLC5A7

8.51e-0610873GO:0015871
GeneOntologyBiologicalProcessregulation of adaptive immune response

PDCD1 CD4 HLA-A HLA-DMA AGER HLA-DRA TNFRSF1B MUC4

1.13e-05252878GO:0002819
GeneOntologyBiologicalProcesstripeptide import across plasma membrane

SLC15A1 SLC15A2

1.76e-052872GO:0140207
GeneOntologyBiologicalProcessadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

PDCD1 IL31RA CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA TNFRSF1B MUC4

2.47e-054628710GO:0002460
GeneOntologyBiologicalProcessregulation of cell adhesion

PDCD1 SLC9A1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA LAMA2 ITGA2 MUC4 ITGB2 PLXNA1 PLXNB1

3.16e-059278714GO:0030155
GeneOntologyBiologicalProcesscell-cell adhesion

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA PKD1L1 ESAM ITGA2 VSIG10 CDH2 MUC4 ITGB2 CDH15

4.07e-0510778715GO:0098609
GeneOntologyBiologicalProcessT cell mediated immune response to tumor cell

PDCD1 HLA-A MUC4

4.72e-0517873GO:0002424
GeneOntologyBiologicalProcessregulation of T cell mediated cytotoxicity

HLA-A AGER HLA-DRA MUC4

7.38e-0553874GO:0001914
GeneOntologyBiologicalProcessMHC protein complex assembly

HLA-A HLA-DMA HLA-DRA

9.12e-0521873GO:0002396
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC protein complex

HLA-A HLA-DMA HLA-DRA

9.12e-0521873GO:0002501
GeneOntologyBiologicalProcesslymphocyte mediated immunity

PDCD1 IL31RA HLA-A HLA-DMA LILRB2 AGER HLA-DRA TNFRSF1B MUC4

1.16e-04449879GO:0002449
GeneOntologyBiologicalProcessleukocyte mediated immunity

PDCD1 IL31RA HLA-A HLA-DMA LILRB2 AGER HLA-DRA TNFRSF1B MUC4 ITGB2

1.55e-045768710GO:0002443
GeneOntologyBiologicalProcessprotein methylation

EEF2KMT METTL21A FAM86B2 EEF1AKMT3

1.74e-0466874GO:0006479
GeneOntologyBiologicalProcessprotein alkylation

EEF2KMT METTL21A FAM86B2 EEF1AKMT3

1.74e-0466874GO:0008213
GeneOntologyBiologicalProcessregulation of postsynaptic density protein 95 clustering

SLC30A1 CDH2

1.74e-045872GO:1902897
GeneOntologyBiologicalProcessoligopeptide import across plasma membrane

SLC15A1 SLC15A2

1.74e-045872GO:0140205
GeneOntologyBiologicalProcessdipeptide import across plasma membrane

SLC15A1 SLC15A2

1.74e-045872GO:0140206
GeneOntologyBiologicalProcessxenobiotic detoxification by transmembrane export across the plasma membrane

SLC22A18 SLC15A2 SLC47A2

1.97e-0427873GO:1990961
GeneOntologyBiologicalProcessregulation of postsynaptic density organization

LILRB2 SLC30A1 CDH2

1.97e-0427873GO:1905874
GeneOntologyBiologicalProcessT cell mediated cytotoxicity

HLA-A AGER HLA-DRA MUC4

2.19e-0470874GO:0001913
GeneOntologyBiologicalProcessresponse to toxic substance

SLC22A18 SLC15A2 SLC22A2 SLC30A1 SLC23A1 SDC1 SLC47A2

2.21e-04289877GO:0009636
GeneOntologyBiologicalProcessxenobiotic export from cell

SLC22A18 SLC15A2 SLC47A2

2.45e-0429873GO:0046618
GeneOntologyBiologicalProcessnegative regulation of T cell mediated immune response to tumor cell

PDCD1 MUC4

2.61e-046872GO:0002841
GeneOntologyBiologicalProcessT cell mediated cytotoxicity directed against tumor cell target

HLA-A MUC4

2.61e-046872GO:0002419
GeneOntologyBiologicalProcessammonium homeostasis

RHCE RHD

2.61e-046872GO:0097272
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC37A1 SLC9A1 ADRA1A CD4 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC30A1 SLC23A1 SLC47A2 RHCE RHD

3.25e-0410178713GO:0098660
GeneOntologyBiologicalProcessregulation of leukocyte mediated immunity

PDCD1 HLA-A AGER HLA-DRA TNFRSF1B MUC4 ITGB2

3.32e-04309877GO:0002703
GeneOntologyBiologicalProcesspositive regulation of leukocyte cell-cell adhesion

CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGB2

3.87e-04317877GO:1903039
GeneOntologyBiologicalProcessimport across plasma membrane

SLC9A1 SLC12A1 SLC15A1 SLC15A2 SLC22A2 SLC30A1

4.29e-04230876GO:0098739
GeneOntologyBiologicalProcessmembrane organization

NEMP1 ABCG1 SLC9A1 SLC12A1 APOO AGER RCC1 ITGA2 SLC30A1 CDH2 ITGB2 TLCD2

4.43e-049148712GO:0061024
GeneOntologyBiologicalProcessregulation of lymphocyte mediated immunity

PDCD1 HLA-A AGER HLA-DRA TNFRSF1B MUC4

4.49e-04232876GO:0002706
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission

ERBB4 ADRA1A LILRB2 AGER LAMA2 SLC7A10

4.59e-04233876GO:0050806
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC9A1 ADRA1A CD4 SLC12A1 SLC15A1 SLC15A2 PKD1L1 SLC30A1 SLC23A1 SLC47A2 RHCE RHD

4.79e-049228712GO:0098662
GeneOntologyBiologicalProcessdipeptide transport

SLC15A1 SLC15A2

4.84e-048872GO:0042938
GeneOntologyBiologicalProcessdipeptide transmembrane transport

SLC15A1 SLC15A2

4.84e-048872GO:0035442
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC44A1 SLC15A2 AGER SLC22A2

5.03e-0487874GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC44A1 SLC15A2 AGER SLC22A2

5.26e-0488874GO:0010232
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC22A18 SLC9A1 ADRA1A CD4 SLC12A1 SLC15A1 SLC15A2 LILRB2 SLCO1A2 SLC22A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2

5.85e-0413748715GO:0006811
GeneOntologyBiologicalProcessregulation of leukocyte cell-cell adhesion

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGB2

5.99e-04447878GO:1903037
GeneOntologyBiologicalProcessregulation of T cell activation

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA TNFRSF1B

7.01e-04458878GO:0050863
GeneOntologyBiologicalProcesscarbohydrate derivative transport

SLC37A1 SPNS1 ABCG1 SLC15A2

7.30e-0496874GO:1901264
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA LAMA2 ITGA2 ITGB2

7.46e-04579879GO:0045785
GeneOntologyBiologicalProcessregulation of cell-cell adhesion

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA MUC4 ITGB2

7.55e-04580879GO:0022407
GeneOntologyBiologicalProcessdetoxification

SLC22A18 SLC15A2 SLC22A2 SLC30A1 SLC47A2

7.68e-04170875GO:0098754
GeneOntologyBiologicalProcesstripeptide transmembrane transport

SLC15A1 SLC15A2

7.74e-0410872GO:0035443
GeneOntologyBiologicalProcessregulation of Rho protein signal transduction

ADRA1A HEG1 CDH2 PLXNB1

7.89e-0498874GO:0035023
GeneOntologyBiologicalProcesspostsynaptic density protein 95 clustering

SLC30A1 CDH2

9.44e-0411872GO:0097119
GeneOntologyBiologicalProcesspeptidyl-lysine trimethylation

EEF2KMT FAM86B2

9.44e-0411872GO:0018023
GeneOntologyBiologicalProcessleukocyte cell-cell adhesion

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGB2

1.03e-03486878GO:0007159
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC9A1 ADRA1A CD4 SLC12A1 SLC15A1 SLC15A2 LILRB2 SLC22A2 PKD1L1 SLC5A7 SLC30A1 SLC23A1 SLC47A2

1.09e-0311578713GO:0006812
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen

HLA-A HLA-DMA HLA-DRA

1.09e-0348873GO:0002478
GeneOntologyBiologicalProcesspositive regulation of cell development

CD4 HLA-DMA LILRB2 AGER HLA-DRA TNFRSF1B SLC30A1 PLXNA1 PLXNB1

1.13e-03614879GO:0010720
GeneOntologyBiologicalProcesscarbohydrate transport

SLC37A1 ERBB4 SLC2A7 C1QTNF12 SLC23A1

1.15e-03186875GO:0008643
GeneOntologyBiologicalProcessmyeloid cell development

NEMP1 TSPAN2 RHCE RHD

1.17e-03109874GO:0061515
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion

CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGB2

1.29e-03389877GO:0022409
GeneOntologyBiologicalProcesstripeptide transport

SLC15A1 SLC15A2

1.33e-0313872GO:0042939
GeneOntologyBiologicalProcessammonium transmembrane transport

RHCE RHD

1.33e-0313872GO:0072488
GeneOntologyBiologicalProcessT cell proliferation

CD4 HLA-A LILRB2 AGER TNFRSF1B ITGB2

1.38e-03288876GO:0042098
GeneOntologyBiologicalProcesspositive regulation of T cell activation

CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA

1.43e-03290876GO:0050870
GeneOntologyBiologicalProcessT cell cytokine production

IL31RA HLA-A TNFRSF1B

1.46e-0353873GO:0002369
GeneOntologyBiologicalProcessregulation of T cell mediated immune response to tumor cell

PDCD1 MUC4

1.55e-0314872GO:0002840
GeneOntologyCellularComponentapical plasma membrane

SLC22A18 SLC9A1 SLC12A1 SLC15A1 SLC15A2 AGER SLC2A7 SLCO1A2 SLC22A2 KNCN SLC5A7 CDH2 MUC4 SLC23A1 SLC47A2

1.74e-094878815GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC22A18 SLC9A1 SLC12A1 SLC15A1 SLC15A2 AGER SLC2A7 SLCO1A2 SLC22A2 KNCN SLC5A7 CDH2 MUC4 SLC23A1 SLC47A2

2.39e-085928815GO:0045177
GeneOntologyCellularComponentmembrane raft

ERBB4 SLC9A1 ADRA1A CD4 HLA-A SLC5A7 TNFRSF1B CDH2 ITGB2 CDH15

2.92e-063628810GO:0045121
GeneOntologyCellularComponentmembrane microdomain

ERBB4 SLC9A1 ADRA1A CD4 HLA-A SLC5A7 TNFRSF1B CDH2 ITGB2 CDH15

3.06e-063648810GO:0098857
GeneOntologyCellularComponentcell surface

PDCD1 ABCG1 SLC9A1 HEG1 IL31RA CD4 SLC12A1 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ITGA2 TREML1 CDH2 ITGB2 SDC1

3.26e-0611118817GO:0009986
GeneOntologyCellularComponentbasal part of cell

ERBB4 SLC9A1 AGER SLCO1A2 SLC22A2 ITGA2 SLC30A1 CDH2 SVOP SLC23A1

4.28e-063788810GO:0045178
GeneOntologyCellularComponentexternal side of plasma membrane

PDCD1 ABCG1 HEG1 IL31RA CD4 HLA-A LILRB2 HLA-DRA ITGA2 ITGB2 SDC1

1.13e-055198811GO:0009897
GeneOntologyCellularComponentbasal plasma membrane

ERBB4 SLC9A1 AGER SLCO1A2 SLC22A2 SLC30A1 CDH2 SVOP SLC23A1

1.82e-05354889GO:0009925
GeneOntologyCellularComponentplasma membrane raft

ERBB4 ADRA1A SLC5A7 CDH2 ITGB2 CDH15

3.68e-05147886GO:0044853
GeneOntologyCellularComponentMHC protein complex

HLA-A HLA-DMA HLA-DRA

1.75e-0426883GO:0042611
GeneOntologyCellularComponentside of membrane

PDCD1 ABCG1 HEG1 IL31RA CD4 HLA-A LILRB2 HLA-DRA ITGA2 ITGB2 ALG12 SDC1

2.95e-048758812GO:0098552
GeneOntologyCellularComponentT-tubule

SLC9A1 ADRA1A SLC30A1 CDH2

3.46e-0479884GO:0030315
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-A HLA-DRA ALG12

4.28e-0435883GO:0098553
GeneOntologyCellularComponentankyrin-1 complex

RHCE RHD

7.71e-0410882GO:0170014
GeneOntologyCellularComponentlumenal side of membrane

HLA-A HLA-DRA ALG12

1.09e-0348883GO:0098576
GeneOntologyCellularComponentpresynaptic membrane

ERBB4 ADRA1A IL31RA SLC22A2 SLC5A7 CDH2

1.12e-03277886GO:0042734
GeneOntologyCellularComponentsarcolemma

SLC9A1 ADRA1A LAMA2 SLC30A1 CDH2

1.25e-03190885GO:0042383
GeneOntologyCellularComponentneuromuscular junction

ERBB4 SLC5A7 LAMA2 CDH15

1.29e-03112884GO:0031594
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA1 PLXNB1

1.33e-0313882GO:0002116
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA2 ITGA2 ITGB2

1.98e-0359883GO:0098636
GeneOntologyCellularComponentMHC class II protein complex

HLA-DMA HLA-DRA

2.29e-0317882GO:0042613
GeneOntologyCellularComponentbasolateral plasma membrane

ERBB4 SLC9A1 SLCO1A2 SLC22A2 SLC30A1 CDH2

2.32e-03320886GO:0016323
GeneOntologyCellularComponentreceptor complex

ERBB4 IL31RA CD4 ITGA2 TNFRSF1B ITGB2 PLXNA1 PLXNB1

3.11e-03581888GO:0043235
GeneOntologyCellularComponentmembrane protein complex

SLC9A1 CD4 APOO HLA-A HLA-DMA LILRB2 HLA-DRA PKD1L1 ITGA2 CDH2 ITGB2 CDH15 RHCE RHD

3.82e-0314988814GO:0098796
DomainMFS_dom

SLC37A1 SLC22A18 SPNS1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 MFSD11 SLC22A2 SVOP

6.44e-101348710IPR020846
DomainMethyltransf_16

EEF2KMT METTL21A FAM86B2 EEF1AKMT3

1.41e-0711874IPR019410
DomainMethyltransf_16

EEF2KMT METTL21A FAM86B2 EEF1AKMT3

1.41e-0711874PF10294
DomainMFS

SLC37A1 SLC22A18 SPNS1 SLC2A7 SLCO1A2 SLC22A2 SVOP

7.10e-07108877PS50850
DomainTetraspanin

CD82 TSPAN31 ROM1 TSPAN2

1.43e-0532874IPR000301
DomainTetraspannin

CD82 TSPAN31 ROM1 TSPAN2

1.62e-0533874PF00335
DomainTetraspanin/Peripherin

CD82 TSPAN31 ROM1 TSPAN2

1.62e-0533874IPR018499
DomainOligopep_transport

SLC15A1 SLC15A2

2.14e-052872IPR004768
DomainIg-like_fold

PDCD1 IL31RA CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ESAM VSIG10 TREML1 PLXNA1 PLXNB1

2.24e-057068713IPR013783
DomainEamA_dom

SLC35G5 SLC35G6 SLC35G4

3.42e-0514873IPR000620
DomainEamA

SLC35G5 SLC35G6 SLC35G4

3.42e-0514873PF00892
DomainPTR2_symporter_CS

SLC15A1 SLC15A2

6.42e-053872IPR018456
DomainPTR2_1

SLC15A1 SLC15A2

6.42e-053872PS01022
DomainIG_LIKE

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ESAM VSIG10 TREML1

9.41e-054918710PS50835
DomainIg-like_dom

PDCD1 CD4 HLA-A HLA-DMA LILRB2 AGER HLA-DRA ESAM VSIG10 TREML1

1.15e-045038710IPR007110
DomainFAM86

EEF2KMT FAM86B2

1.28e-044872PF14904
DomainFAM86

EEF2KMT FAM86B2

1.28e-044872IPR029426
DomainPTR2_2

SLC15A1 SLC15A2

1.28e-044872PS01023
DomainIg/MHC_CS

HLA-A HLA-DMA AGER HLA-DRA

1.54e-0458874IPR003006
DomainIG_MHC

HLA-A HLA-DMA AGER HLA-DRA

1.76e-0460874PS00290
DomainPOT_fam

SLC15A1 SLC15A2

2.13e-045872IPR000109
DomainPTR2

SLC15A1 SLC15A2

2.13e-045872PF00854
DomainAmmonium_transpt

RHCE RHD

2.13e-045872IPR001905
DomainAmmonium_transp

RHCE RHD

2.13e-045872PF00909
DomainNH4_transpt_AmtB-like_dom

RHCE RHD

2.13e-045872IPR024041
DomainRhesusRHD

RHCE RHD

2.13e-045872IPR002229
DomainTM4_1

CD82 TSPAN31 TSPAN2

2.35e-0426873PS00421
Domain-

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

2.44e-041208753.40.50.150
Domain-

PDCD1 IL31RA CD4 HLA-A AGER HLA-DRA ESAM VSIG10 TREML1 PLXNA1 PLXNB1

2.51e-0466387112.60.40.10
DomainSAM-dependent_MTases

EEF2KMT METTL13 METTL21A FAM86B2 EEF1AKMT3

2.64e-04122875IPR029063
DomainMHC_II_alpha

HLA-DMA HLA-DRA

3.18e-046872PF00993
DomainSugar_transporter_CS

SLC2A7 SLC22A2 MUC4

4.39e-0432873IPR005829
DomainTetraspanin_EC2

CD82 ROM1 TSPAN2

4.39e-0432873IPR008952
Domain-

RHCE RHD

4.44e-0478721.10.3430.10
DomainAmmonium/urea_transptr

RHCE RHD

4.44e-047872IPR029020
DomainMHC_II_a_N

HLA-DMA HLA-DRA

4.44e-047872IPR001003
DomainMFS_1

SLC37A1 SLC22A18 SPNS1 SVOP

4.59e-0477874PF07690
DomainMFS

SLC37A1 SLC22A18 SPNS1 SVOP

4.59e-0477874IPR011701
DomainMFS_sugar_transport-like

SLC2A7 SLC22A2 SVOP

6.24e-0436873IPR005828
DomainSugar_tr

SLC2A7 SLC22A2 SVOP

6.24e-0436873PF00083
DomainPlexin_cytopl

PLXNA1 PLXNB1

7.56e-049872PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA1 PLXNB1

7.56e-049872IPR013548
DomainPlexin

PLXNA1 PLXNB1

7.56e-049872IPR031148
DomainOrgcat_transp/SVOP

SLC22A2 SVOP

7.56e-049872IPR004749
DomainPSI

ITGB2 PLXNA1 PLXNB1

1.13e-0344873IPR016201
DomainPSI

ITGB2 PLXNA1 PLXNB1

1.28e-0346873SM00423
DomainV-set

PDCD1 CD4 ESAM VSIG10 TREML1

1.69e-03184875PF07686
DomainIGc1

HLA-A HLA-DMA HLA-DRA

2.26e-0356873SM00407
DomainIg_V-set

PDCD1 CD4 ESAM VSIG10 TREML1

2.38e-03199875IPR013106
DomainIg_C1-set

HLA-A HLA-DMA HLA-DRA

2.50e-0358873IPR003597
DomainSUGAR_TRANSPORT_2

SLC2A7 SLC22A2

2.79e-0317872PS00217
DomainIG

PDCD1 CD4 LILRB2 AGER ESAM VSIG10 TREML1

3.50e-03421877SM00409
DomainIg_sub

PDCD1 CD4 LILRB2 AGER ESAM VSIG10 TREML1

3.50e-03421877IPR003599
DomainTetraspanin_CS

CD82 TSPAN2

4.25e-0321872IPR018503
DomainAA-permease/SLC12A_dom

SLC12A1 SLC7A10

4.66e-0322872IPR004841
DomainAA_permease

SLC12A1 SLC7A10

4.66e-0322872PF00324
DomainIGv

PDCD1 CD4 VSIG10

5.18e-0375873SM00406
DomainSUGAR_TRANSPORT_1

SLC2A7 SLC22A2

5.54e-0324872PS00216
DomainCadherin_cytoplasmic-dom

CDH2 CDH15

6.00e-0325872IPR000233
DomainIntegrin_dom

ITGA2 ITGB2

6.00e-0325872IPR032695
DomainCadherin_C

CDH2 CDH15

6.00e-0325872PF01049
DomainIPT

PLXNA1 PLXNB1

6.98e-0327872SM00429
DomainCatenin_binding_dom

CDH2 CDH15

8.03e-0329872IPR027397
Domain-

CDH2 CDH15

8.03e-03298724.10.900.10
DomainTIG

PLXNA1 PLXNB1

9.14e-0331872PF01833
DomainSema

PLXNA1 PLXNB1

9.14e-0331872SM00630
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A18 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 SLC5A7 SLC30A1 SLC7A10 SLC47A2

5.69e-112496313M5988
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

PDCD1 CD4 HLA-A HLA-DMA HLA-DRA ESAM CDH2 ITGB2 SDC1 CDH15

3.32e-101336310M16476
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A18 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 SLC5A7 SLC30A1 SLC7A10

5.07e-102386312MM15076
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A18 SLC44A1 SLC22A2 SLC5A7 SLC30A1 SLC47A2

1.93e-0684636M27334
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC22A18 ABCG1 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 SLC5A7 SLC30A1 SLC7A10 SLC47A2

3.40e-067366314M27287
PathwayWP_11P112_COPY_NUMBER_VARIATION_SYNDROME

CD82 CD4 HLA-DMA HLA-DRA ITGB2

4.86e-0656635M48075
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC22A18 ABCG1 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 SLC5A7 SLC30A1 SLC7A10

7.78e-066816313MM14985
PathwayKEGG_VIRAL_MYOCARDITIS

HLA-A HLA-DMA HLA-DRA LAMA2 ITGB2

1.47e-0570635M12294
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A18 SLC44A1 SLC22A2 SLC5A7 SLC30A1

2.20e-0576635MM15072
PathwayREACTOME_PD_1_SIGNALING

PDCD1 CD4 HLA-DRA

9.19e-0520633MM15001
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A1 SLC12A1 SLC15A1 SLC15A2 SLC7A10

1.19e-04108635M823
PathwayREACTOME_PROTEIN_METHYLATION

EEF2KMT METTL21A FAM86B2

1.23e-0422633MM15519
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A1 SLC12A1 SLC15A1 SLC15A2 SLC7A10

1.24e-04109635MM15074
PathwayREACTOME_PD_1_SIGNALING

PDCD1 CD4 HLA-DRA

2.57e-0428633M18810
PathwayREACTOME_ORGANIC_CATION_TRANSPORT

SLC22A18 SLC22A2

5.41e-048632MM15191
PathwayWP_ACUTE_VIRAL_MYOCARDITIS

CD4 HLA-DMA LAMA2 ITGB2

5.59e-0485634M39776
PathwayKEGG_ALLOGRAFT_REJECTION

HLA-A HLA-DMA HLA-DRA

5.93e-0437633M18615
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

CD4 HLA-A HLA-DMA HLA-DRA

6.38e-0488634M16004
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

HLA-A HLA-DMA HLA-DRA

8.03e-0441633M13519
PathwayREACTOME_ORGANIC_CATION_TRANSPORT

SLC22A18 SLC22A2

8.64e-0410632M27450
PathwayKEGG_TYPE_I_DIABETES_MELLITUS

HLA-A HLA-DMA HLA-DRA

9.24e-0443633M12617
PathwayBIOCARTA_BBCELL_PATHWAY

CD4 HLA-DRA

1.05e-0311632M22030
PathwayBIOCARTA_THELPER_PATHWAY

CD4 ITGB2

1.26e-0312632M6427
PathwayBIOCARTA_THELPER_PATHWAY

CD4 ITGB2

1.26e-0312632MM1506
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A18 SLC22A2

1.26e-0312632MM15192
PathwayBIOCARTA_IL5_PATHWAY

CD4 HLA-DRA

1.49e-0313632M18928
PathwayBIOCARTA_CTL_PATHWAY

HLA-A ITGB2

1.49e-0313632M1462
PathwayKEGG_AUTOIMMUNE_THYROID_DISEASE

HLA-A HLA-DMA HLA-DRA

1.61e-0352633M13103
PathwayBIOCARTA_MHC_PATHWAY

HLA-A HLA-DRA

1.73e-0314632M22023
PathwayBIOCARTA_BLYMPHOCYTE_PATHWAY

HLA-DRA ITGB2

1.73e-0314632M1473
PathwayREACTOME_SYNDECAN_INTERACTIONS

ITGA2 SDC1

1.73e-0314632MM14923
PathwayBIOCARTA_TCRA_PATHWAY

CD4 HLA-DRA

1.73e-0314632M10765
PathwayREACTOME_OTHER_INTERLEUKIN_SIGNALING

CD4 SDC1

1.99e-0315632MM15131
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION

HLA-DMA HLA-DRA

1.99e-0315632M47588
PathwayKEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES

HLA-DMA HLA-DRA

1.99e-0315632M47604
PathwayBIOCARTA_ASBCELL_PATHWAY

CD4 HLA-DRA

1.99e-0315632M7298
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A18 SLC22A2

1.99e-0315632M888
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

ITGA2 CDH2 ITGB2 CDH15

2.08e-03121634M39823
PathwayWP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA

CD4 TNFRSF1B ITGB2

2.20e-0358633MM15966
PathwayREACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE

CD4 HLA-DRA

2.27e-0316632MM14808
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA2 ITGA2 SDC1

2.31e-0359633M27218
PathwayWP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA

CD4 TNFRSF1B ITGB2

2.43e-0360633M39508
PathwayREACTOME_PROTEIN_METHYLATION

EEF2KMT METTL21A

2.56e-0317632M27782
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

HLA-A HLA-DMA HLA-DRA ITGA2

2.63e-03129634M39693
PathwayPID_IL12_2PATHWAY

CD4 HLA-A HLA-DRA

2.67e-0362633M54
Pubmed

Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.

ERBB4 MUC4 PLXNA1 PLXNB1

1.25e-081188425315821
Pubmed

RT-PCR of fatty acid elongases.

SLC35G5 SLC35G6 SLC35G4

6.25e-0848839056918
Pubmed

Emergence of primate genes by retrotransposon-mediated sequence transduction.

SLC35G5 SLC35G6 SLC35G4

6.25e-08488317101974
Pubmed

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.

CD4 HLA-A HLA-DMA HLA-DRA

8.88e-081788415194762
Pubmed

The activity of Nef on HIV-1 infectivity.

CD4 HLA-A HLA-DMA HLA-DRA

8.88e-081788424904546
Pubmed

Nef performance in macrophages: the master orchestrator of viral persistence and spread.

CD4 HLA-A HLA-DMA HLA-DRA

1.80e-072088422103834
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC44A1 SLC15A2 AGER SLC22A2 LAMA2 ESAM

2.91e-0710588630280653
Pubmed

Adhesion signaling by a novel mitotic substrate of src kinases.

CDCP1 CDH2 SDC1

3.11e-07688316007225
Pubmed

The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules.

CD82 HLA-DMA HLA-DRA

3.11e-0768839759843
Pubmed

Role of HIV-1 Nef protein for virus replication in vitro.

CD4 HLA-A HLA-DMA HLA-DRA

3.27e-072388419770068
Pubmed

Editorial. Nef: a notorious enigmatic factor in HIV biology.

CD4 HLA-A HLA-DMA HLA-DRA

3.91e-072488422175768
Pubmed

HIV accessory proteins and surviving the host cell.

CD4 HLA-A HLA-DMA HLA-DRA

4.65e-072588416091223
Pubmed

Interactions of viral protein U (Vpu) with cellular factors.

CD4 HLA-A HLA-DMA HLA-DRA

6.42e-072788420012522
Pubmed

[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway].

CD4 HLA-A HLA-DMA HLA-DRA

6.42e-072788412836198
Pubmed

One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.

CD4 HLA-A HLA-DMA HLA-DRA

7.48e-072888422103833
Pubmed

HIV/SIV escape from immune surveillance: focus on Nef.

CD4 HLA-A HLA-DMA HLA-DRA

8.66e-072988415078178
Pubmed

Modelling thymic HIV-1 Nef effects.

CD4 HLA-A HLA-DMA HLA-DRA

9.97e-073088416454711
Pubmed

Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.

CD4 HLA-A HLA-DMA HLA-DRA

1.14e-063188421922073
Pubmed

Immunoregulatory effects of HIV-1 Nef protein.

CD4 HLA-A HLA-DMA HLA-DRA

1.30e-063288419449444
Pubmed

Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.

CD4 HLA-A HLA-DMA HLA-DRA

1.48e-063388416354571
Pubmed

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

ERBB4 ABCG1 METTL21A LAMA2 SDC1

3.25e-068988524529757
Pubmed

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

CD4 HLA-A HLA-DMA HLA-DRA

6.28e-064788419149577
Pubmed

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.

RHCE RHD

6.33e-0628828188244
Pubmed

DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.

RHCE RHD

6.33e-06288217900276
Pubmed

RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.

RHCE RHD

6.33e-06288232697929
Pubmed

Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function.

SLC15A1 SLC15A2

6.33e-06288211944083
Pubmed

Review: the molecular basis of the Rh blood group phenotypes.

RHCE RHD

6.33e-06288215373666
Pubmed

Peptide transporters and their roles in physiological processes and drug disposition.

SLC15A1 SLC15A2

6.33e-06288218668438
Pubmed

Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.

RHCE RHD

6.33e-06288226579938
Pubmed

Lack of interaction between the peptidomimetic substrates captopril and cephradine.

SLC15A1 SLC15A2

6.33e-06288219246733
Pubmed

Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.

RHCE RHD

6.33e-06288234968422
Pubmed

Regarding the size of Rh proteins.

RHCE RHD

6.33e-0628821898705
Pubmed

PCR screening for common weak D types shows different distributions in three Central European populations.

RHCE RHD

6.33e-06288211161244
Pubmed

RH diversity in Mali: characterization of a new haplotype RHD*DIVa/RHCE*ceTI(D2).

RHCE RHD

6.33e-06288225857637
Pubmed

The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL.

RHCE RHD

6.33e-06288222738288
Pubmed

Multiple Rh messenger RNA isoforms are produced by alternative splicing.

RHCE RHD

6.33e-0628821379850
Pubmed

Functional characterization of HIV-1 Nef mutants in the context of viral infection.

CD4 HLA-A

6.33e-06288216684552
Pubmed

Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.

SLC15A1 SLC15A2

6.33e-06288218367661
Pubmed

Characterization of the mouse Rh blood group gene.

RHCE RHD

6.33e-06288210329015
Pubmed

Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents.

SLC15A1 SLC15A2

6.33e-06288216202478
Pubmed

Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains.

PLXNA1 PLXNB1

6.33e-06288212559962
Pubmed

Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin.

CD82 CDH2

6.33e-06288226592446
Pubmed

DX5+ CD4+ T cells modulate CD4+ T-cell response via inhibition of IL-12 production by DCs.

CD4 ITGA2

6.33e-06288223169063
Pubmed

RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.

RHCE RHD

6.33e-06288223772606
Pubmed

Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.

RHCE RHD

6.33e-0628823135863
Pubmed

Sequences and evolution of mammalian RH gene transcripts and proteins.

RHCE RHD

6.33e-0628829811965
Pubmed

Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.

RHCE RHD

6.33e-06288212393640
Pubmed

Molecular genetic basis of the human Rhesus blood group system.

RHCE RHD

6.33e-0628828220426
Pubmed

Integrin alpha2beta1 inhibits Fas-mediated apoptosis in T lymphocytes by protein phosphatase 2A-dependent activation of the MAPK/ERK pathway.

ITGA2 ITGB2

6.33e-06288213679375
Pubmed

Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.

RHCE RHD

6.33e-0628827916743
Pubmed

TNFR2 blockade alone or in combination with PD-1 blockade shows therapeutic efficacy in murine cancer models.

PDCD1 TNFRSF1B

6.33e-06288232449229
Pubmed

RHD*DOL1 and RHD*DOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.

RHCE RHD

6.33e-06288222690701
Pubmed

No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.

RHCE RHD

6.33e-06288226872772
Pubmed

RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa.

RHCE RHD

6.33e-06288222804620
Pubmed

Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection.

CD4 HLA-A

6.33e-06288225423108
Pubmed

Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy.

PDCD1 SLC9A1

6.33e-06288230262908
Pubmed

Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.

RHCE RHD

6.33e-0628827789951
Pubmed

HLA anchor optimization of the melan-A-HLA-A2 epitope within a long peptide is required for efficient cross-priming of human tumor-reactive T cells.

MLANA HLA-A

6.33e-06288222291187
Pubmed

SDC1 and ITGA2 as novel prognostic biomarkers for PDAC related to IPMN.

ITGA2 SDC1

6.33e-06288237907515
Pubmed

E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.

RHCE RHD

6.33e-06288211724987
Pubmed

The Rh blood group system: a review.

RHCE RHD

6.33e-06288210627438
Pubmed

Comparison of human and monkey peptide transporters: PEPT1 and PEPT2.

SLC15A1 SLC15A2

6.33e-06288215981923
Pubmed

Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.

RHCE RHD

6.33e-06288237823181
Pubmed

Sequence diversity of the Rh blood group system in Basques.

RHCE RHD

6.33e-06288230089826
Pubmed

Type I Collagen Signaling Regulates Opposing Fibrotic Pathways through α2β1 Integrin.

ITGA2 ITGB2

6.33e-06288232692932
Pubmed

Loss of the α2β1 integrin alters human papilloma virus-induced squamous carcinoma progression in vivo and in vitro.

ITGA2 ITGB2

6.33e-06288222046385
Pubmed

Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.

RHCE RHD

6.33e-06288229193104
Pubmed

Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.

SLC15A1 SLC15A2

6.33e-06288218713951
Pubmed

Nonredundant Upregulation of CD112R (PVRIG) and PD-1 on Cytotoxic T Lymphocytes Located in T Cell Nests of Colorectal Cancer.

PDCD1 PVRIG

6.33e-06288236788088
Pubmed

RHCE variants inherited with altered RHD alleles in Brazilian blood donors.

RHCE RHD

6.33e-06288227111588
Pubmed

Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.

RHCE RHD

6.33e-0628828822955
Pubmed

Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.

RHCE RHD

6.33e-0628828808597
Pubmed

Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.

RHCE RHD

6.33e-06288212201845
Pubmed

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C.

CD4 HLA-A

6.33e-06288226607225
Pubmed

Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility.

PLXNA1 PLXNB1

6.33e-06288214734633
Pubmed

Variant RH alleles and Rh immunisation in patients with sickle cell disease.

RHCE RHD

6.33e-06288224960646
Pubmed

The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters.

SLC15A1 SLC15A2

6.33e-06288220067523
Pubmed

Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.

RHCE RHD

6.33e-06288230418133
Pubmed

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.

RHCE RHD

6.33e-06288223550903
Pubmed

Molecular cloning and primary structure of the human blood group RhD polypeptide.

RHCE RHD

6.33e-0628821438298
Pubmed

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy.

CD4 HLA-A

6.33e-06288221849975
Pubmed

Molecular background of D(C)(e) haplotypes within the white population.

RHCE RHD

6.33e-06288212084172
Pubmed

The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.

RHCE RHD

6.33e-06288210924335
Pubmed

Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition.

MLANA HLA-A

6.33e-06288217719062
Pubmed

A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.

RHCE RHD

6.33e-06288212857961
Pubmed

Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.

RHCE RHD

6.33e-06288220233350
Pubmed

A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.

RHCE RHD

6.33e-0628828900235
Pubmed

RHD*weak partial 4.0 is associated with an altered RHCE*ce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.

RHCE RHD

6.33e-06288223742316
Pubmed

A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.

RHCE RHD

6.33e-06288224033223
Pubmed

HIV-1 Nef sequence and functional compartmentalization in the gut is not due to differential cytotoxic T lymphocyte selective pressure.

CD4 HLA-A

6.33e-06288224058696
Pubmed

Ineffectual targeting of HIV-1 Nef by cytotoxic T lymphocytes in acute infection results in no functional impairment or viremia reduction.

CD4 HLA-A

6.33e-06288224789790
Pubmed

Screening of the interaction between xenobiotic transporters and PDZ proteins.

SLC15A1 SLC15A2 SLCO1A2

6.97e-061588315553237
Pubmed

Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.

CD4 HLA-DMA HLA-DRA

6.97e-06158838168144
Pubmed

HIV-gp120 can block CD4-class II MHC-mediated adhesion.

CD4 HLA-DMA HLA-DRA

6.97e-06158831967269
Pubmed

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.

CD4 HLA-DMA HLA-DRA

8.56e-06168832846691
Pubmed

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.

CD4 HLA-DMA HLA-DRA

8.56e-06168832543930
Pubmed

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.

CD4 HLA-DMA HLA-DRA

8.56e-06168831978941
Pubmed

Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families.

HLA-A AGER HLA-DRA

1.24e-051888318987644
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

SLC9A1 HLA-A SLC15A1 ITGA2 CDCP1 SLC30A1 SDC1 PLXNA1 PLXNB1

1.43e-0556988930639242
Pubmed

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.

HLA-A HLA-DMA HLA-DRA

1.73e-052088312427289
InteractionCD82 interactions

CD82 CD4 HLA-DMA HLA-DRA CDCP1 ITGB2

1.88e-0761836int:CD82
InteractionCD63 interactions

GPD2 CD82 TSPAN31 HLA-DRA SLC22A2 SDC1 TSPAN2

4.48e-07114837int:CD63
InteractionNHERF4 interactions

TAS2R8 SLC15A1 SLC15A2 SLCO1A2

1.85e-0622834int:NHERF4
InteractionHLA-DMA interactions

CD82 HLA-DMA HLA-DRA

7.92e-0610833int:HLA-DMA
InteractionSLC47A2 interactions

SLC22A2 SLC47A2

5.01e-053832int:SLC47A2
CytobandEnsembl 112 genes in cytogenetic band chr1p36

TMCO4 SLC9A1 SLC2A7 TNFRSF1B C1QTNF12 RHCE RHD

3.69e-04681897chr1p36
Cytoband6p21.3

HLA-A HLA-DMA AGER HLA-DRA

1.46e-032508946p21.3
Cytoband3q13.33

SLC15A2 TIMMDC1

1.56e-03308923q13.33
Cytoband21q22.3

SLC37A1 ABCG1 ITGB2

2.02e-0312889321q22.3
GeneFamilySolute carriers

SLC37A1 SLC22A18 SLC9A1 SLC44A1 SLC12A1 SLC15A1 SLC15A2 SLC2A7 SLCO1A2 SLC22A2 SLC5A7 SLC35G5 SLC35G6 SLC30A1 SLC23A1 SLC7A10 SLC47A2 SLC35G4

3.08e-153956718752
GeneFamilyADAM metallopeptidase domain containing|CD molecules

PDCD1 CD82 SLC44A1 CD4 LILRB2 ITGA2 TNFRSF1B CDCP1 CDH2 ITGB2 SDC1 RHCE RHD

1.80e-093946713471
GeneFamilyCD molecules|Tetraspanins

CD82 TSPAN31 ROM1 TSPAN2

6.50e-0633674768
GeneFamilyCD molecules|Type I classical cadherins

CDH2 CDH15

1.34e-0456721185
GeneFamilyMethyltransferase like

METTL13 METTL21A EEF1AKMT3

2.45e-0433673963
GeneFamilyAdenosine receptors|V-set domain containing

PDCD1 CD4 ESAM VSIG10 TREML1

3.45e-04163675590
GeneFamilyPlexins

PLXNA1 PLXNB1

4.79e-049672683
GeneFamilyC1-set domain containing

HLA-A HLA-DMA HLA-DRA

5.04e-0442673591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-A HLA-DMA HLA-DRA

5.78e-0444673588
GeneFamilyGlycosyltransferase family 6|Blood group antigens

RHCE RHD

8.29e-0337672454
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CD4 AGER

9.64e-0340672592
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SPNS1 SLC9A1 HEG1 TSPAN31 HLA-A MFSD11 MPDU1 TNFRSF1B SLC30A1 ALG12 SDC1 PLXNA1

2.57e-066818712M5314
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SPNS1 SLC9A1 HEG1 TSPAN31 HLA-A MFSD11 MPDU1 TNFRSF1B SLC30A1 ALG12 SDC1 PLXNA1

3.56e-067038712MM1055
CoexpressionBROWNE_HCMV_INFECTION_30MIN_DN

SLC12A1 RCC1 TNFRSF1B MUC4 ITGB2 RHCE

9.02e-06145876M0
CoexpressionGAO_LARGE_INTESTINE_24W_C11_PANETH_LIKE_CELL

ABCG1 CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2 UAP1L1

1.25e-05324878M39160
CoexpressionLI_PBMC_MENOMUNE_A_C_Y_W_135_AGE_18_45YO_CORRELATED_WITH_ANTIBODY_RESPONSE_3DY_POSITIVE

CD4 HLA-A HLA-DMA HLA-DRA

1.27e-0543874M41036
CoexpressionJIANG_MELANOMA_TRM10_LAMINA_PROPRIA

PDCD1 HLA-A HLA-DMA HLA-DRA ITGB2

1.33e-0591875M48974
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

PRRG2 SLC22A18 TBC1D9B SLC12A1 TSPAN31 LAMA2 ROM1 ITGB2 SDC1

3.22e-05482879M12144
CoexpressionCUI_DEVELOPING_HEART_C8_MACROPHAGE

CD4 HLA-A HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

3.70e-05275877M39305
CoexpressionAIZARANI_LIVER_C31_KUPFFER_CELLS_5

METTL21A LILRB2 TNFRSF1B SVOP TLCD2

5.06e-05120875M39130
CoexpressionHE_LIM_SUN_FETAL_LUNG_C6_MUC16_POS_CILIATED_CELL

CD82 ITGA2 MUC4 SLC23A1

5.45e-0562874M45790
CoexpressionWILENSKY_RESPONSE_TO_DARAPLADIB

CD4 HLA-DMA ITGB2

1.09e-0428873M18107
CoexpressionAIZARANI_LIVER_C6_KUPFFER_CELLS_2

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

1.14e-04228876M39110
CoexpressionDESCARTES_FETAL_STOMACH_MYELOID_CELLS

CD4 HLA-DMA HLA-DRA TNFRSF1B

1.21e-0476874M40302
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#5_top-relative-expression-ranked_1000

PRRG2 SDSL AGER C1QTNF12 PLXNB1

1.35e-0576855gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k5
ToppCellwk_08-11-Hematologic-Myeloid-APOE+_Mac1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ABCG1 CD82 HLA-A HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

6.11e-09197898121ec3f6d978de2f6c2cc397f7327d2e5587ab8b
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNA1 PLXNB1

1.46e-07198897b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNA1 PLXNB1

1.51e-07199897d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SDSL CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

1.51e-071998979df2c79904dacf029ec9df1f1cde72d871189a82
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNA1 PLXNB1

1.56e-072008972dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDCD1 CD4 PVRIG TNFRSF1B ITGB2 SLC7A10

1.28e-06172896c74c1d47b133eb5d0f762a06e421252a76b4672b
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEMP1 CD4 SLC22A2 RCC1 CDCP1 TMEM255A

1.61e-0617989654621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SLC15A2 AGER SLC5A7 SDC1 PLXNA1 PLXNB1

1.61e-061798961603117b52623663458a977c94bf7f9f6c1114b8
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMCO3 ERBB4 SLC5A7 LAMA2 CDH2 RHCE

1.66e-0618089638490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMCO3 ABCG1 CD82 PCSK1N ETNPPL TSPAN2

1.66e-06180896350ba05cec45a788ab33530cc1346daddb00f884
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMCO3 ABCG1 CD82 PCSK1N ETNPPL TSPAN2

1.77e-061828960beffe6b9b36cfd196ec98a18f6ded080c162f90
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC15A2 SLC5A7 ITGA2 CDCP1 SDR16C5 MUC4

1.89e-06184896575de705053da8b289670b5c40c1627c0833b5ed
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2 UAP1L1

2.01e-0618689673185d48c874e18dd2e2eeea67c32d3182ea88a5
ToppCell(2)_Dendritic_Cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.28e-061908965163a5be95fb6c2609bfa3d69166af172f74e724
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SLC12A1 SLC22A2 PCSK1N SDC1 PLXNB1

2.42e-061928968769b67d1cad1be65da3938f916e5bf88f88f6b8
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL31RA CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

2.42e-0619289622f335e6e75a694cdccafe189b5ee7815ef28c03
ToppCellmetastatic_Lymph_Node-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

PDCD1 CD82 CD4 HLA-A HLA-DMA TNFRSF1B

2.49e-06193896bac302e69455aaaf1c18f3272bb213242664d747
ToppCell10x5'-blood|World / Manually curated celltypes from each tissue

HLA-A LILRB2 ESAM TNFRSF1B TREML1 ITGB2

2.49e-06193896359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCellnormal_Lymph_Node-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

PDCD1 CD82 HLA-A HLA-DMA TNFRSF1B SLC7A10

2.49e-0619389651fd629e91c85881c3231486d6d2fb2c65fcd77b
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC15A2 AGER CDCP1 MUC4 SLC23A1 PLXNB1

2.57e-061948963701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell(2)_MNPs|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.57e-061948969cd64e325ec233da82c463b09262efe93d2a92ee
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC15A2 AGER CDCP1 MUC4 SLC23A1 PLXNB1

2.57e-0619489665f9bf126be26114c2c3f4c46d48318986212a92
ToppCellMonocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD4 HLA-DMA LILRB2 HLA-DRA CDCP1 ITGB2

2.57e-061948963e104e85574894c04791252d466d438fc809dde3
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.57e-06194896abce1e824ce2512741c313a5ec336d12f580b093
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.57e-061948966810586080cc893e3270b9c8bee2d95ed78e2893
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

PDCD1 ABCG1 CD82 HLA-A HLA-DMA HLA-DRA

2.57e-061948967b8fe5b702b99aac5bff7de8ac0b5cabb3235b56
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.64e-06195896028622b234551b185977fbee10c06851a45456a5
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

PDCD1 CD82 CD4 HLA-A HLA-DMA HLA-DRA

2.72e-061968965a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.72e-06196896f667430a61bc962e4d033818a05348bf40762041
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.72e-0619689663b841457d12fb9dd25630e3c348d3ef53463f86
ToppCellILEUM-non-inflamed-(3)_Resident_macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SDSL CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

2.81e-061978963af24354b6a93c7d105b9fa6549cf215107b9203
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNB1

2.81e-06197896b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD4 HLA-DRA PCSK1N ITGB2 SLC23A1 CDH15

2.81e-061978968fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.81e-06197896e27577a1fa553986044512f52c252a587f864510
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPNS1 ABCG1 CD4 HLA-A HLA-DMA HLA-DRA

2.81e-061978964f022bae7af2ca23689cc0d35046a7e23dba6e9c
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.81e-0619789649511ea2330a516456007e73bc3195334433011c
ToppCellwk_20-22-Hematologic-Myeloid-CX3CR1+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SDSL CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

2.81e-061978960e231b12881ab1f0f08040f248ea2e6fba34bc2f
ToppCellwk_15-18-Hematologic-Myeloid-CX3CR1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.81e-06197896701334bc164e3b41132232f27574a87e9c3a5be5
ToppCellASK452-Immune-Macrophages|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

HLA-A HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.81e-061978964cd26ccadfcb0ad63610d06c07cbdb1e463c6af8
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPNS1 ABCG1 CD4 HLA-A HLA-DMA HLA-DRA

2.81e-0619789669671ed173057a67265ac39ed03fbd57dbd22c5c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-06198896d681aff379720261d85f9c1c6030932c5046960e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-061988968fe5e6b563bee2179b0f17d6591870d7dd76e891
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-06198896dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-06198896acb84681569651447d684aa3960f0510d7ff17e8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-06198896c00dbe61dc25602f19bd42a760646680002961ca
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

CD4 FMO4 HLA-DRA ITGB2 SLC23A1 CDH15

2.89e-06198896d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 SLC12A1 APOO HLA-A PCSK1N SDC1

2.89e-061988960de0c612a1f030debde28bfd6fbae3697e8b48de
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD82 SLC44A1 HLA-A HLA-DRA PCSK1N ITGA2

2.89e-061988960d9d401190792fd61434f1b82548253187d805f0
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD4 HLA-DRA PCSK1N ITGB2 SLC23A1 CDH15

2.89e-06198896436f3a9ef31b0991765bb97c21960f20fa71d578
ToppCellASK452-Immune|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

HLA-A HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.89e-0619889647d37a05edd68b73c75bb81a477707413d6464e1
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC15A2 AGER SLCO1A2 ITGA2 SDR16C5 SDC1

2.97e-06199896456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-06199896f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HEG1 SLC44A1 HLA-A HLA-DMA HLA-DRA ESAM

2.97e-061998965d976d57872a8a25a11fe8cd53b01aa21a1a519a
ToppCellCaecum-T_cell-Treg|Caecum / Region, Cell class and subclass

PDCD1 CD4 HLA-A TNFRSF1B ITGB2 SLC7A10

2.97e-06199896ab0b32c077ac26d32a293dcf686af6984980793f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-06199896e48b1fde8d3b3abd3c7362c27dc74d26e7d33078
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC15A2 AGER SLCO1A2 ITGA2 SDR16C5 SDC1

2.97e-061998965263338242f95c04690d0795749ccc20b0d19f7a
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-061998965ceeed92f831d068ff4bb3994f420002338330e7
ToppCellCaecum-(1)_T_cell-(15)_Treg|Caecum / shred on region, Cell_type, and subtype

PDCD1 CD4 HLA-A TNFRSF1B ITGB2 SLC7A10

2.97e-0619989612c22b07a231c9dc548e9dc37e0a60296a4a6273
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNB1

2.97e-06199896a270630626df614f8605abddb7dee7c4d74f6149
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC15A2 AGER SLCO1A2 ITGA2 SDR16C5 SDC1

2.97e-06199896c11365653c69a5dfb37946231f8af05149a61a71
ToppCellwk_20-22-Hematologic-Myeloid|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-061998960740166c51ce63edf83c4b98fce057f1440116d7
ToppCellwk_15-18-Hematologic-Myeloid-SPP1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-06199896c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CD4 HLA-DRA PCSK1N CDH2 ITGB2 CDH15

2.97e-06199896f197ab861767ee06aa47b86c537fb3d8c2b2bc3e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.97e-06199896bdb865c0f4a2af7ad4b677b7d9a1e9ae2b7ec5b5
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLC15A2 AGER ITGA2 SDC1 PLXNA1 PLXNB1

3.06e-06200896ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellHematolymphoid|World / cells hierarchy compared to all cells using T-Statistic

CD4 HLA-DMA HLA-DRA TNFRSF1B TREML1 ITGB2

3.06e-06200896354bed3bfad1fab0c0c7f26925f8d91b80c6e0c7
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC37A1 SLC15A2 AGER ITGA2 SDC1 PLXNB1

3.06e-062008968683445ad5b70748c4a1f12eb77d47623085147e
ToppCellParenchyma_Control_(B.)-Immune-TX-MoAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

3.06e-06200896670ef1e68be0d2c6ea20ab4dea1d051a3cc89799
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD4 HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

3.06e-062008961438b84096de9b4abe9e6213caa07f6bdff67358
ToppCellASK440-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

HEG1 SLC44A1 HLA-A HLA-DRA ESAM

4.67e-061228952f76ec3b527e9528fbb006599a96e8bbdf9e0e62
ToppCellAT1-AT2_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

HEG1 SLC15A2 AGER SLC5A7 PLXNB1

1.08e-05145895cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 ADRA1A SLC5A7 TMEM255A TSPAN2

1.40e-051538959c6fce56300ba5053efda59a438d63a808c497c0
ToppCellMonocytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SMCO3 LILRB2 TNFRSF1B ITGB2 RHD

1.64e-05158895c3096b3a914a1a15ebe3664613e94b951f8555fc
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC15A2 EEF1AKMT3 TNFRSF1B PLXNA1 ELP4

1.69e-051598951472536eea61d4f13033efe42f128bae1614fa74
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HLA-A HLA-DRA SLC35G6 ITGB2 TMEM255A

1.69e-051598952060e7ed5627976b48fea4a2328762b6fa308db1
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDCD1 CD4 PVRIG PCSK1N CDH15

1.74e-05160895dee756a2dc9725520d439e7273c489c2284015d8
ToppCellControl-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDCD1 LILRB2 HLA-DRA TNFRSF1B ITGB2

1.85e-05162895aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|tumor_Lung / Location, Cell class and cell subclass

CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

1.85e-051628959ac3242511315224ed94582aca9e9a3786cd01a0
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A18 SLC15A2 SLC22A2 ETNPPL SLC23A1

1.85e-05162895de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EEF2KMT SYT15 METTL13 ITGA2 TMEM255A

2.02e-0516589562457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.08e-0516689583d0c26ccee605df6b04bbca31661bf4ff4f22ba
ToppCellBac-SEP-Lymphocyte-B-B_memory|Bac-SEP / Disease, Lineage and Cell Type

CD82 HLA-DMA HLA-DRA SLC35G6 SDR16C5

2.33e-0517089586db153984437ef1447eae8ef30a40be0925ffd5
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

ABCG1 SLC5A7 ITGA2 CDCP1 MUC4

2.47e-051728959d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

ERBB4 HLA-A HLA-DMA HLA-DRA ITGB2

2.54e-051738951e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 LILRB2 HLA-DRA TNFRSF1B ITGB2

2.68e-05175895c9dc6aa652ac887470806a950311657c423d9495
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.68e-05175895fe27c3279f660b5be4193005394b77163c599d32
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

SLC15A2 AGER ITGA2 SDC1 PLXNA1

2.75e-05176895458720776b0151cd55acc352d509599cb62f0ca8
ToppCellprimary_visual_cortex-Non-neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD82 SLC15A2 LAMA2 ETNPPL SLC7A10

2.75e-051768952c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDCD1 CD4 PCSK1N ITGB2 CDH15

2.75e-05176895f3bbe8c1a8d132705eac360cf531261271d84588
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC22A18 MLANA PDCD1 CD82 CD4

2.83e-05177895fd4a297e519b3959811a462d63feebff76429031
ToppCelldroplet-Lung-nan-21m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLANA PDCD1 CD82 CD4 VSIG10

2.83e-051778958cc74873f4d2d0f81042426a687b01750abc72d2
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLANA PDCD1 CD82 CD4 VSIG10

2.83e-05177895fe0f6a73264632bdd4f9fbc22de2d155ba2bcf8c
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-regulatory_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC22A18 MLANA PDCD1 CD82 CD4

2.83e-05177895e995230ef207dcd87eab4550617589016ffa9970
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPNS1 ABCG1 CD4 HLA-A ITGB2

2.91e-051788950b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-A KNCN SLC35G6 TNFRSF1B ITGB2

2.91e-05178895a96941fef62c2f4533c557ef825ae3265f8f52db
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

2.99e-05179895409364d916c5e7e2291284cc74351d8f8a8447ac
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DMA LILRB2 HLA-DRA TNFRSF1B ITGB2

2.99e-05179895716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC15A2 AGER MUC4 SVOP SDC1

2.99e-05179895bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 LILRB2 HLA-DRA TNFRSF1B ITGB2

2.99e-05179895ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD4 HLA-DMA LILRB2 HLA-DRA ITGB2

3.07e-051808957af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ComputationalGenes in the cancer module 162.

SLC12A1 SLC15A1 SLC15A2

1.04e-0419533MODULE_162
ComputationalNeighborhood of FGR

LILRB2 TNFRSF1B ITGB2

5.07e-0432533GNF2_FGR
ComputationalProgrammed cell death.

PDCD1 ADRA1A TNFRSF1B

5.56e-0433533MODULE_300
ComputationalMembranal receptors.

MLANA CD82 CD4 HLA-A SLC15A2 LILRB2 HLA-DRA TNFRSF1B ITGB2

8.57e-04517539MODULE_64
ComputationalImmune (humoral) and inflammatory response.

CD4 HLA-A HLA-DMA SLC15A2 LILRB2 HLA-DRA TNFRSF1B ITGB2 SDC1

1.26e-03546539MODULE_84
ComputationalGenes in the cancer module 293.

HLA-A HLA-DRA

1.53e-0312532MODULE_293
ComputationalNeighborhood of S100A4

LILRB2 TNFRSF1B ITGB2

1.57e-0347533GNF2_S100A4
ComputationalGenes in the cancer module 27.

ERBB4 CD4 HLA-A LILRB2 HLA-DRA TNFRSF1B ITGB2

1.68e-03355537MODULE_27
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDCD1 HLA-DRA ITGB2

1.78e-0349533GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_CYTOTOXIC
ComputationalGenes in the cancer module 412.

ITGA2 ITGB2

1.80e-0313532MODULE_412
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HLA-A HLA-DMA HLA-DRA

1.88e-0350533GAVISH_3CA_MALIGNANT_METAPROGRAM_17_INTERFERON_MHC_II_1
ComputationalGenes in the cancer module 143.

HLA-A HLA-DRA

2.09e-0314532MODULE_143
DrugAC1L1KTH

CD4 SLC15A1 HLA-DMA SLC15A2 SLC7A10

1.09e-0648875CID000005647
DrugD1-G

SLC15A1 SLC15A2 SLCO1A2

8.70e-0611873CID011171679
Drugglycylsarcosine

SLC9A1 SLC15A1 SLC15A2 SLCO1A2

9.51e-0635874CID000093131
Drug1-bromo-2-butene

HLA-DMA ITGA2

1.44e-052872CID000122414
Drugdioxophosphonium

HLA-DMA ITGA2

1.44e-052872CID006365079
Drugglycylsarcosine

SLC15A1 SLC15A2

1.44e-052872ctd:C004194
Drugquinaprilat

SLC15A1 SLC15A2

1.44e-052872ctd:C054501
DrugPOBr3

HLA-DMA ITGA2

1.44e-052872CID000522692
Drugmoexipril

SLC15A1 SLC15A2

1.44e-052872ctd:C058302
DrugAC1Q6DJO

CD4 HLA-A HLA-DMA HLA-DRA LAMA2

2.89e-0593875CID000000630
Drugspirapril

SLC15A1 SLC15A2

4.32e-053872ctd:C052555
DrugAC1LA4RF

CD4 SLC12A1

4.32e-053872CID000461688
Drugpivalic anhydride

HEG1 HLA-DMA

4.32e-053872CID000015234
Drug(R)-10-hydroxystearate

SPNS1 IL31RA

4.32e-053872CID000012520
Diseasesporadic amyotrophic lateral sclerosis

ERBB4 ABCG1 METTL21A LAMA2 ETNPPL PLXNA1

3.53e-06140866EFO_0001357
DiseaseMethionine sulfoxide measurement

TMEM132C CD4 FMO4

5.16e-0612863EFO_0021650
DiseaseAnemia, Hemolytic, Congenital

RHCE RHD

8.40e-062862C0002881
Diseaselupus nephritis (is_implicated_in)

PDCD1 AGER TNFRSF1B

1.89e-0518863DOID:0080162 (is_implicated_in)
DiseaseRh Deficiency Syndrome

RHCE RHD

2.51e-053862C0272052
DiseaseRh-Null, Regulator Type

RHCE RHD

2.51e-053862C1849387
Diseasemultiple sclerosis

MLANA TSPAN31 HLA-A SLC15A2 HLA-DRA MRGPRE TIMMDC1 SLC7A10 CDH15

5.93e-05594869MONDO_0005301
Diseasepsoriasis (implicated_via_orthology)

TNFRSF1B ITGB2

1.75e-047862DOID:8893 (implicated_via_orthology)
DiseaseSchizophrenia

ERBB4 ADRA1A HLA-A AGER LAMA2 ESAM ETNPPL TNFRSF1B SLC7A10 RHD

2.49e-048838610C0036341
Diseasegamma-glutamylisoleucine measurement

LILRB2 LAMA2

2.98e-049862EFO_0021139
Diseaseacute kidney failure (is_implicated_in)

AGER SLC22A2

3.72e-0410862DOID:3021 (is_implicated_in)
Diseaseresponse to statin, myopathy

SLCO1A2 CDCP1

4.54e-0411862EFO_0004145, GO_0036273
DiseaseParanoid Schizophrenia

HLA-A TNFRSF1B

6.41e-0413862C0036349
Diseaseserum IgE measurement

TMEM132C HLA-A HLA-DRA

8.76e-0464863EFO_0004579
Diseasemultiple sclerosis (is_implicated_in)

PDCD1 AGER HLA-DRA

1.28e-0373863DOID:2377 (is_implicated_in)
Diseaserenovascular hypertension (biomarker_via_orthology)

SLC9A1 LAMA2

1.39e-0319862DOID:1591 (biomarker_via_orthology)
Diseasetoxic shock syndrome (is_marker_for)

PDCD1 HLA-DRA

1.39e-0319862DOID:14115 (is_marker_for)
DiseaseLeft Ventricle Remodeling

SLC9A1 ADRA1A

1.70e-0321862C0600520
DiseaseVentricular Remodeling

SLC9A1 ADRA1A

1.70e-0321862C0600519
Diseaseperiodontitis (biomarker_via_orthology)

PDCD1 AGER

1.70e-0321862DOID:824 (biomarker_via_orthology)
Diseaselung adenocarcinoma (is_marker_for)

SLC22A18 MUC4 SDC1

1.99e-0385863DOID:3910 (is_marker_for)
Diseasesystemic lupus erythematosus

TMEM132C ERBB4 SLC12A1 HLA-A HLA-DRA C1QTNF12 TIMMDC1 CDH2

2.31e-03799868MONDO_0007915
Diseasecongestive heart failure (is_implicated_in)

SLC9A1 TNFRSF1B

2.81e-0327862DOID:6000 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GVIGGLFILVIVGLT

ERBB4

656

Q15303
IGIGLLIGLLYLGIG

ABCG1

431

P45844
TGGKLLALSLIIGVG

SLC7A10

191

Q9NS82
IAAVGGGVLLLSALG

CDCP1

671

Q9H5V8
AILLGVILGGLILFG

ADRA1A

26

P35348
VILGGLILFGVLGNI

ADRA1A

31

P35348
ELGAGTGIVGILAAL

EEF1AKMT3

81

Q96AZ1
VLLGPQLVLLGGVGA

C1QTNF12

11

Q5T7M4
LIGDIRGIGLFIGID

ETNPPL

356

Q8TBG4
QLIVRGVLGLGVIFG

ALG12

96

Q9BV10
ENLGIILGVGVGVAI

CD82

226

P27701
ILGVGVGVAIIELLG

CD82

231

P27701
LVLTLGQGDVGQLGL

RCC1

36

P18754
GILGGLGTAALLIGV

AGER

346

Q15109
EIVLITGAGSGLGRL

SDR16C5

41

Q8N3Y7
ALGGLLLLGVGTFVV

MUC4

5376

Q99102
VLELGSGAGLTGLAI

FAM86B2

161

P0C5J1
ILVGGGALATVLGLS

GPD2

11

P43304
GILTVILGVLLLIGC

MLANA

31

Q16655
VIGFAGLIGLLLARG

APOO

116

Q9BUR5
LIGGGLLILIILTVA

IL31RA

526

Q8NI17
LGGLLGSLLVGLLVD

SLC2A7

86

Q6PXP3
RAGGVGLLVLLLLGL

PCSK1N

11

Q9UHG2
VGVVGGLLGSLVLLV

PDCD1

171

Q15116
IVGIGGGGGLLLLVI

PLXNA1

1246

Q9UIW2
GGGGLLLLVIVAVLI

PLXNA1

1251

Q9UIW2
VGLGVGTSLLALGVI

PLXNB1

1491

O43157
GVGGGGTVRLLLILS

NEMP1

21

O14524
VLELGSGAGLTGLAI

EEF2KMT

161

Q96G04
AIIGLIGLKGSILSG

FMO4

366

P31512
QSGLGRHLGVVIGIL

LILRB2

451

Q8N423
GVLLLLLLSGGLGGV

LAMA2

6

P24043
VVIAAAGGGLLLILG

HEG1

1251

Q9ULI3
AGGGLLLILGIALIV

HEG1

1256

Q9ULI3
SLIGLSGIFIGIGEI

MFSD11

276

O43934
IILSLTEGLGLGGLL

MRGPRE

26

Q86SM8
PTGVIIGSIIAGILL

ITGA2

1131

P17301
ELGAGTGLVGIVAAL

METTL21A

71

Q8WXB1
GGTVAGIVLIGILLL

ITGB2

706

P05107
GIFGGILAGVISDRL

SLC37A1

376

P57057
VLGGVAGLLLFIGLG

CD4

401

P01730
AFGLGVLGIIVGIVL

HLA-DMA

236

P28067
ALGLTVGLVGIIIGT

HLA-DRA

221

P01903
AGAVVGTLVGLGLLA

ESAM

251

Q96AP7
GTLVGLGLLAGLVLL

ESAM

256

Q96AP7
IPIVGIIAGLVLLGA

HLA-A

306

P04439
GGVFIGAAVLGLLIL

KNCN

41

A6PVL3
ILVILGSLGGTGVLW

SLC44A1

246

Q8WWI5
DQLLGGGLAVGTVLL

ELP4

71

Q96EB1
LEIPLALLVVGLGGG

METTL13

491

Q8N6R0
LIGLALIALGTGGIK

SLC15A1

126

P46059
SLIGLSLIALGTGGI

SLC15A2

146

Q16348
GVLGLVAGGLVLLLP

SLC22A2

501

O15244
LAGGTGLSLGALVIV

CDH15

596

P55291
VVGLLGSLGLGAISE

PKD1L1

951

Q8TDX9
VGAGLGTGAIIAILL

CDH2

716

P19022
VLGVGGAAVLGIATL

MIEF2

31

Q96C03
AIIVGGRDIGLLVGG

SLC5A7

41

Q9GZV3
GLLGSILGLIIILGP

SLC35G5

161

Q96KT7
ILVLRGLVGFGIGGV

SVOP

176

Q8N4V2
ALVIGGTIGGLLLLL

SYT15

6

Q9BQS2
GTIGGLLLLLLIGAS

SYT15

11

Q9BQS2
GVLSIVGISLVLGTL

SLC47A2

371

Q86VL8
LLIGLATVGGGTVIG

TMCO4

191

Q5TGY1
LLGALLGKVIEGHGV

TMEM132C

21

Q8N3T6
VGLFLGIITAAVLGG

TMEM255A

231

Q5JRV8
EVLGGVIAGGLVGLI

SDC1

251

P18827
EAGIGLGVLIILLST

SLC12A1

206

Q13621
IGLVETGAIIGPLIG

SLCO1A2

196

P46721
LLSKGLGLGIVAGSL

MPDU1

41

O75352
GVGVILGSLLGGTLV

SLC22A18

161

Q96BI1
GGLLAGVVAGLLEVG

SDSL

176

Q96GA7
GGLTGLLVGTLDVVL

TBC1D9B

36

Q66K14
GLLGSILGLIIIVGP

SLC35G4

161

P0C7Q5
VLGLVAGLISVGGAK

RHD

296

Q02161
VLGLVAGLISIGGAK

RHCE

296

P18577
PLALVTLGGIGLVTV

TLCD2

196

A6NGC4
GGGLLVVGLGLALAL

ROM1

111

Q03395
VEVVIGLLGLPGALL

SLC23A1

166

Q9UHI7
LTGVLGVGLGVEISR

SPNS1

331

Q9H2V7
RGLVAGGIIGALLGT

TIMMDC1

186

Q9NPL8
AVGLTGGILLIVLAG

PRRG2

111

O14669
VAVLLLAGGQGTRLG

UAP1L1

106

Q3KQV9
GLGLVSSIHIIGGVI

TSPAN31

36

Q12999
IVVGLLVGGLIKGVG

SLC9A1

136

P19634
GFVGALGTGALVVLL

TMDD1

226

P0DPE3
GASLLGSIGVAVLGL

SMCO3

156

A2RU48
GLLGSILGLIIIVGP

SLC35G6

161

P0C7Q6
IGGIVGTIVSLLLLG

VSIG10

411

Q8N0Z9
ILITGEFILGILGNG

TAS2R8

11

Q9NYW2
PVGLIVGVTALGLLI

TNFRSF1B

261

P20333
LQLIGIVGIGIAGLT

TSPAN2

186

O60636
VLGVGVAGLLVNVLG

SLC30A1

116

Q9Y6M5
LLLLLLGLEGQGIVG

TREML1

6

Q86YW5
DLAGILGVSGVLLFG

PVRIG

171

Q6DKI7