Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	protein kinase CK2 complex	CSNK2A1 CSNK2A3	1.12e-04	4	91	2	GO:0005956
Domain	-	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1 PLXNB3	2.21e-04	333	91	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1 PLXNB3	2.30e-04	335	91	8	IPR015943
Domain	PH_BEACH	NBEAL2 LYST	3.48e-04	6	91	2	PF14844
Domain	WD_REPEATS_1	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1	4.19e-04	278	91	7	PS00678
Domain	WD_REPEATS_2	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1	4.28e-04	279	91	7	PS50082
Domain	WD_REPEATS_REGION	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1	4.28e-04	279	91	7	PS50294
Domain	WD40_repeat_dom	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST RIC1	6.20e-04	297	91	7	IPR017986
Domain	Ank_2	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	6.41e-04	215	91	6	PF12796
Domain	PH-BEACH_dom	NBEAL2 LYST	6.45e-04	8	91	2	IPR023362
Domain	-	NBEAL2 LYST	6.45e-04	8	91	2	2.30.29.40
Domain	PH_BEACH	NBEAL2 LYST	6.45e-04	8	91	2	PS51783
Domain	BEACH_dom	NBEAL2 LYST	8.27e-04	9	91	2	IPR000409
Domain	BEACH	NBEAL2 LYST	8.27e-04	9	91	2	PS50197
Domain	Beach	NBEAL2 LYST	8.27e-04	9	91	2	PF02138
Domain	-	NBEAL2 LYST	8.27e-04	9	91	2	1.10.1540.10
Domain	Beach	NBEAL2 LYST	8.27e-04	9	91	2	SM01026
Domain	Cation_efflux	SLC30A2 SLC30A10	1.03e-03	10	91	2	IPR002524
Domain	Cation_efflux	SLC30A2 SLC30A10	1.03e-03	10	91	2	PF01545
Domain	Anoctamin	ANO7 ANO8	1.03e-03	10	91	2	PF04547
Domain	Anoctamin	ANO7 ANO8	1.03e-03	10	91	2	IPR007632
Domain	-	SLC30A2 SLC30A10	1.25e-03	11	91	2	1.20.1510.10
Domain	Cation_efflux_TMD	SLC30A2 SLC30A10	1.25e-03	11	91	2	IPR027469
Domain	ARM-type_fold	TNPO1 DOCK3 MROH1 NBEAL2 PRKDC ARID1A LYST	1.34e-03	339	91	7	IPR016024
Domain	-	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.34e-03	248	91	6	1.25.40.20
Domain	ANK	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.43e-03	251	91	6	SM00248
Domain	ANK_REPEAT	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.49e-03	253	91	6	PS50088
Domain	Ankyrin_rpt-contain_dom	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.52e-03	254	91	6	IPR020683
Domain	ANK_REP_REGION	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.52e-03	254	91	6	PS50297
Domain	HEAT	TNPO1 MROH1 PRKDC	1.65e-03	48	91	3	PF02985
Domain	WD40	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST	1.67e-03	259	91	6	PF00400
Domain	Ankyrin_rpt	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.77e-03	262	91	6	IPR002110
Domain	WD40	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST	1.99e-03	268	91	6	SM00320
Domain	ARM-like	TNPO1 MROH1 NBEAL2 RIPOR3 PRKDC ARID1A	2.06e-03	270	91	6	IPR011989
Domain	WD40_repeat	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST	2.14e-03	272	91	6	IPR001680
Domain	PKS_ER	FASN CRYZL1	2.70e-03	16	91	2	SM00829
Domain	PKS_ER	FASN CRYZL1	2.70e-03	16	91	2	IPR020843
Domain	HEAT	TNPO1 MROH1 PRKDC	2.84e-03	58	91	3	IPR000357
Domain	ADH_zinc_N	FASN CRYZL1	3.80e-03	19	91	2	PF00107
Domain	ADH_C	FASN CRYZL1	3.80e-03	19	91	2	IPR013149
Domain	ConA-like_dom	TRIM72 CELSR1 NBEAL2 COL27A1 NRP1	4.35e-03	219	91	5	IPR013320
Domain	-	TNPO1 MROH1 RIPOR3 PRKDC ARID1A	4.61e-03	222	91	5	1.25.10.10
Domain	HEAT_REPEAT	TNPO1 MROH1 PRKDC	4.84e-03	70	91	3	PS50077
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 DOCK3 FASN CELSR1 MROH1 NBEAL2 TMEM132A HIP1R POLRMT WDR90 PRKDC ARID1A LYST ADCY9 RIC1 ANO8	3.17e-08	1105	92	16	35748872
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TNPO1 TANC2 FASN RBBP5 ANAPC2 HIP1R GEMIN4 HLTF PRKDC ARID1A	3.36e-06	582	92	10	20467437
Pubmed	Translocation of bacteria from the gastrointestinal tract in immunodeficient mice.	PRKDC LYST	6.92e-06	2	92	2	8709573
Pubmed	An immunocompromised murine model of chronic Bartonella infection.	PRKDC LYST	6.92e-06	2	92	2	20395436
Pubmed	Protective immunity to HIV-1 in SCID/beige mice reconstituted with peripheral blood lymphocytes of exposed but uninfected individuals.	PRKDC LYST	6.92e-06	2	92	2	8962121
Pubmed	ARID1A-deficient cells require HDAC6 for progression of endometrial carcinoma.	HDAC6 ARID1A	6.92e-06	2	92	2	35167193
Pubmed	Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells.	PRKDC LYST	6.92e-06	2	92	2	23094018
Pubmed	Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.	CSNK2A1 CSNK2A3	6.92e-06	2	92	2	14646071
Pubmed	The role of sodium-coupled glucose co-transporter 3 in the satiety effect of portal glucose sensing.	TRPM5 SLC2A2	6.92e-06	2	92	2	24024129
Pubmed	Clinicopathological correlation of ARID1A status with HDAC6 and its related factors in ovarian clear cell carcinoma.	HDAC6 ARID1A	6.92e-06	2	92	2	30787326
Pubmed	Branhamella catarrhalis pathogenesis in SCID and SCID/beige mice. Brief report.	PRKDC LYST	6.92e-06	2	92	2	8267959
Pubmed	Assignment of casein kinase 2 alpha sequences to two different human chromosomes.	CSNK2A1 CSNK2A3	6.92e-06	2	92	2	1577469
Pubmed	Nonspecific immune responses and mechanisms of resistance to Eimeria papillata infections in mice.	PRKDC LYST	6.92e-06	2	92	2	9234770
Pubmed	Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.	PRKDC LYST	6.92e-06	2	92	2	17392156
Pubmed	CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle.	CSNK2A1 TOPBP1	6.92e-06	2	92	2	34544280
Pubmed	Signs and lesions of experimental Sendai virus infection in two genetically distinct strains of SCID/beige mice.	PRKDC LYST	6.92e-06	2	92	2	8140728
Pubmed	Spontaneous and experimental infections in scid and scid/beige mice.	PRKDC LYST	6.92e-06	2	92	2	8320959
Pubmed	The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.	PRKDC LYST	6.92e-06	2	92	2	20739949
Pubmed	Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.	CSNK2A1 CSNK2A3	6.92e-06	2	92	2	12860116
Pubmed	Infection of the laboratory mouse with the intracellular pathogen Ehrlichia chaffeensis.	PRKDC LYST	6.92e-06	2	92	2	9673277
Pubmed	Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation.	PRKDC LYST	6.92e-06	2	92	2	8418200
Pubmed	ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.	PRKDC LYST	6.92e-06	2	92	2	19249873
Pubmed	Studies of virus-induced myocardial injury in mice: value of the scid mutation on different genetic backgrounds and combined with other mutations.	PRKDC LYST	6.92e-06	2	92	2	8391609
Pubmed	Murine granulated metrial gland cell population in beige (bg/bg) and SCID (scid/scid) genotypes.	PRKDC LYST	6.92e-06	2	92	2	8075241
Pubmed	Molecular cloning of the human casein kinase II alpha subunit.	CSNK2A1 CSNK2A3	6.92e-06	2	92	2	2752008
Pubmed	Mycobacterium avium subspecies paratuberculosis triggers intestinal pathophysiologic changes in beige/scid mice.	PRKDC LYST	6.92e-06	2	92	2	11924817
Pubmed	DNA-PKcs inhibition impairs HDAC6-mediated HSP90 chaperone function on Aurora A and enhances HDACs inhibitor-induced cell killing by increasing mitotic aberrant spindle assembly.	HDAC6 PRKDC	6.92e-06	2	92	2	33404279
Pubmed	Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.	CSNK2A1 CSNK2A3	6.92e-06	2	92	2	8420794
Pubmed	SCID-bg mice as xenograft recipients.	PRKDC LYST	6.92e-06	2	92	2	9175014
Pubmed	Extracellular protein kinase CK2 is a novel associating protein of neuropilin-1.	CSNK2A1 NRP1	6.92e-06	2	92	2	19486891
Pubmed	Comparison of susceptibility of inbred and outbred infant mice to Escherichia coli heat-stable enterotoxin STa.	PRKDC LYST	6.92e-06	2	92	2	1639480
Pubmed	Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment.	TRIM72 MGMT	6.92e-06	2	92	2	34958003
Pubmed	O6-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms.	MGMT SLC2A2	6.92e-06	2	92	2	33287738
Pubmed	Evaluation of three lines of immunodeficient mice for the study of spontaneous metastatic tumors.	PRKDC LYST	6.92e-06	2	92	2	10225324
Pubmed	Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	15684395
Pubmed	Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.	PRKDC LYST	2.07e-05	3	92	2	29242210
Pubmed	Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	2174700
Pubmed	CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.	PRKDC LYST	2.07e-05	3	92	2	23792169
Pubmed	TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.	TNPO1 ARID1A	2.07e-05	3	92	2	34044070
Pubmed	Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	1766873
Pubmed	Significance of phosphatase and tensin homologue (PTEN), O(6)-methylguanine-DNA methyltransferase (MGMT), and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein expression in gynaecomastia.	MGMT PRKDC	2.07e-05	3	92	2	19589246
Pubmed	ARID1A-mutated ovarian cancers depend on HDAC6 activity.	HDAC6 ARID1A	2.07e-05	3	92	2	28737768
Pubmed	Pulmonary alveolar proteinosis. A spontaneous and inducible disease in immunodeficient germ-free mice.	PRKDC LYST	2.07e-05	3	92	2	7717446
Pubmed	Interactions of the scid or beige mutations with the viable motheaten mutation.	PRKDC LYST	2.07e-05	3	92	2	8781712
Pubmed	TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.	TNPO1 NRP1	2.07e-05	3	92	2	33987449
Pubmed	Crystallization and preliminary characterization of crystals of human protein kinase CK2.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	11092945
Pubmed	Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	12102635
Pubmed	Neuropilin 1 directly interacts with Fer kinase to mediate semaphorin 3A-induced death of cortical neurons.	FER NRP1	2.07e-05	3	92	2	20133938
Pubmed	Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.	PRKDC LYST	2.07e-05	3	92	2	8806787
Pubmed	Defective killing of Candida albicans hyphae by neutrophils from beige mice.	PRKDC LYST	2.07e-05	3	92	2	7769315
Pubmed	Trastuzumab/pertuzumab combination therapy stimulates antitumor responses through complement-dependent cytotoxicity and phagocytosis.	PRKDC LYST	2.07e-05	3	92	2	35167491
Pubmed	Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.	CSNK2A1 CSNK2A3	2.07e-05	3	92	2	20625391
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	HACE1 TMEM132A TOPBP1 PLXNB3 CEMIP	2.56e-05	130	92	5	12421765
Pubmed	Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.	CSNK2A1 GEMIN4 PRKDC	3.95e-05	25	92	3	15385968
Pubmed	Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets.	CSNK2A1 CREB3L3	4.14e-05	4	92	2	26108621
Pubmed	Strain-dependent leakiness of mice with severe combined immune deficiency.	PRKDC LYST	4.14e-05	4	92	2	8473734
Pubmed	Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells.	CSNK2A1 PRKDC	4.14e-05	4	92	2	20711232
Pubmed	Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.	PRKDC LYST	4.14e-05	4	92	2	10202929
Pubmed	Rejection responses to allogeneic hepatocytes by reconstituted SCID mice, CD4, KO, and CD8 KO mice.	PRKDC LYST	4.14e-05	4	92	2	11152110
Pubmed	DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.	ANAPC2 PRKDC	4.14e-05	4	92	2	26221070
Pubmed	Inhibition of DNA-dependent protein kinase reduced palmitate and oleate-induced lipid accumulation in HepG2 cells.	FASN PRKDC	4.14e-05	4	92	2	23184344
Pubmed	The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.	CSNK2A1 TOPBP1	4.14e-05	4	92	2	20065034
Pubmed	Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice.	FASN HMGCR	4.14e-05	4	92	2	11254743
Pubmed	MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.	CSNK2A1 TOPBP1	4.14e-05	4	92	2	30898438
Pubmed	ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.	ELF3 PRKDC	4.14e-05	4	92	2	37345534
Pubmed	Polycation-dependent, Ca2+-antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase.	CSNK2A1 FER	4.14e-05	4	92	2	3472906
Pubmed	The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer.	PRKDC LYST	4.14e-05	4	92	2	27703030
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RBBP5 ANAPC2 POLRMT HLTF TIMELESS EDEM1 RIC1 NRP1 CEMIP	5.76e-05	650	92	9	38777146
Pubmed	Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress.	HDAC6 CSNK2A1	6.89e-05	5	92	2	21486957
Pubmed	Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium.	PRKDC LYST	6.89e-05	5	92	2	22617213
Pubmed	DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).	PRKDC GRM4	6.89e-05	5	92	2	11801738
Pubmed	A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination.	CSNK2A1 TOPBP1	6.89e-05	5	92	2	35597237
Pubmed	Protein phosphorylation is a regulatory mechanism for O6-alkylguanine-DNA alkyltransferase in human brain tumor cells.	MGMT CSNK2A1	6.89e-05	5	92	2	10667577
Pubmed	IL-12, independently of IFN-gamma, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder.	PRKDC LYST	6.89e-05	5	92	2	10358203
Pubmed	Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage.	CSNK2A1 PRKDC	6.89e-05	5	92	2	22404984
Pubmed	Umami taste in mice uses multiple receptors and transduction pathways.	TRPM5 GRM4	6.89e-05	5	92	2	22183726
Pubmed	PEG3 controls lipogenesis through ACLY.	FASN HMGCR	6.89e-05	5	92	2	34048454
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NBEAL2 ANAPC2 TOPBP1 HIP1R SPG11 WDR90 EDEM1 ADCY9	8.26e-05	529	92	8	14621295
Pubmed	The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.	CSNK2A1 PRKDC	1.03e-04	6	92	2	10951572
Pubmed	T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice.	PRKDC LYST	1.03e-04	6	92	2	17438029
Pubmed	MDC1 collaborates with TopBP1 in DNA replication checkpoint control.	CSNK2A1 TOPBP1	1.03e-04	6	92	2	21482717
Pubmed	Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.	PRKDC LYST	1.03e-04	6	92	2	10841521
Pubmed	Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.	CSNK2A1 PRKDC	1.03e-04	6	92	2	11883897
Pubmed	Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer.	PRKDC LYST	1.44e-04	7	92	2	38788720
Pubmed	Identification of potential biomarkers for early and advanced gastric adenocarcinoma detection.	IL11 CEMIP	1.44e-04	7	92	2	21443102
Pubmed	Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity.	SLC30A2 SLC30A10	1.44e-04	7	92	2	26728129
Pubmed	A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.	CSNK2A1 CSNK2A3	1.44e-04	7	92	2	11239457
Pubmed	SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway.	TOPBP1 TIMELESS	1.44e-04	7	92	2	24990965
Pubmed	Humanized mice in translational biomedical research.	PRKDC LYST	1.44e-04	7	92	2	17259968
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TANC2 AGO3 TMEM132A ANO8	1.54e-04	101	92	4	10997877
Pubmed	Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.	CREB3L3 EDEM1	1.92e-04	8	92	2	16469704
Pubmed	The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.	ANO7 ANO8	1.92e-04	8	92	2	21984732
Pubmed	Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1.	CSNK2A1 TOPBP1	1.92e-04	8	92	2	20545769
Pubmed	Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.	PRKDC LYST	1.92e-04	8	92	2	29946151
Pubmed	Genetically determined murine models of immunodeficiency.	PRKDC LYST	1.92e-04	8	92	2	3297105
Pubmed	Expression and function of epithelial anoctamins.	ANO7 ANO8	1.92e-04	8	92	2	20056604
Pubmed	A nonclassical MHC class I molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor.	PRKDC LYST	1.92e-04	8	92	2	15383569
Pubmed	p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.	CSNK2A1 CSNK2A3	1.92e-04	8	92	2	12393879
Pubmed	Anoctamins are a family of Ca2+-activated Cl- channels.	ANO7 ANO8	1.92e-04	8	92	2	22946059
Pubmed	Acetoacetyl-CoA synthetase is essential for normal neuronal development.	FASN HMGCR	1.92e-04	8	92	2	23000407
Interaction	CD40 interactions	TNPO1 HDAC6 NBEAL2 EIF2B4 HIP1R GEMIN4 SLC30A2	5.59e-06	153	90	7	int:CD40
GeneFamily	Ankyrin repeat domain containing	TANC2 ANKRD65 KIDINS220 SOWAHD HACE1 ANKDD1B	1.48e-04	242	60	6	403
GeneFamily	WD repeat domain containing	CORO2B WDR64 RBBP5 NBEAL2 WDR90 LYST	2.27e-04	262	60	6	362
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL2 LYST	3.84e-04	9	60	2	1230
GeneFamily	Anoctamins	ANO7 ANO8	4.79e-04	10	60	2	865
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGQ PIGZ	2.18e-03	21	60	2	680
GeneFamily	Transient receptor potential cation channels	TRPM5 TRPM2	3.87e-03	28	60	2	249
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TANC2 CORO2B TRPM5 COL27A1 HIP1R ANO7 ELF3	1.44e-07	191	92	7	54f07e4de61735051498846afb44b1798bed8144
ToppCell	droplet-Fat-Mat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 ELF3 ERN2 CEACAM20 SLC30A10 SLC2A2	8.80e-07	156	92	6	cfd7f56f3155db677684827607e9008e975dbe70
ToppCell	droplet-Fat-Mat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 ELF3 ERN2 CEACAM20 SLC30A10 SLC2A2	8.80e-07	156	92	6	0d79b4172896574b00faf00e87254f68d76f5512
ToppCell	droplet-Fat-Mat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 ELF3 ERN2 CEACAM20 SLC30A10 SLC2A2	8.80e-07	156	92	6	f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO2B TRPM5 FMN1 COL27A1 HIP1R ELF3	1.10e-06	162	92	6	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIP1R ANO7 ELF3 WDR90 ERN2 PIGZ	1.45e-06	170	92	6	2c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIP1R ANO7 ELF3 WDR90 ERN2 PIGZ	1.45e-06	170	92	6	9bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIGQ HDAC6 NEU3 LYST LILRB4	1.87e-05	157	92	5	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIGQ HDAC6 NEU3 LYST LILRB4	1.87e-05	157	92	5	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIGQ HDAC6 NEU3 LYST LILRB4	1.87e-05	157	92	5	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 NBEAL2 TRPM2 LRG1 LILRB4	1.93e-05	158	92	5	0ed844ab625351a46b74edddf082279ed1bae5c6
ToppCell	facs-Lung-Endomucin-24m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 NBEAL2 TRPM2 LRG1 LILRB4	1.93e-05	158	92	5	b3a810314e253b4fd0f578e759c36fdd21722934
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 TRPM2 LYST LRG1 LILRB4	1.99e-05	159	92	5	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 TRPM2 LYST LRG1 LILRB4	1.99e-05	159	92	5	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELSR1 RARRES1 ELF3 ERN2 SLC30A10	1.99e-05	159	92	5	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIDINS220 TMEM132A ANKDD1B LRG1 PLXNB3	2.11e-05	161	92	5	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FASN HMGCR CREB3L3 LRG1 SLC2A2	2.37e-05	165	92	5	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	droplet-Thymus-nan-3m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM5 TRPM2 ADCY9 IL9R LILRB4	2.44e-05	166	92	5	c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM72 COL27A1 RIPOR3 HMGCLL1 NRP1	2.59e-05	168	92	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	facs-BAT-Fat-3m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 TMEM132A LYST LRG1 LILRB4	2.74e-05	170	92	5	8fd0a55266066a51266ab616c38c883e2680bcf4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELSR1 CORO2B DPY19L2 TMEM178A CCDC191	2.82e-05	171	92	5	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	CELSR1 RARRES1 FMN1 TRPM2 LILRB4	3.06e-05	174	92	5	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	DPY19L2 AGO3 HMGCR ITGA4 LYST	3.23e-05	176	92	5	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CELSR1 RARRES1 CATSPERB ELF3 ERN2	3.32e-05	177	92	5	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CELSR1 RARRES1 CATSPERB ELF3 ERN2	3.32e-05	177	92	5	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	droplet-Fat-Scat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM72 TMEM178A TIMELESS SLC30A2 NRP1	3.79e-05	182	92	5	fea094fe0e7796c084e60b5310c1559658633f7a
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	BNC2 RARRES1 RIPOR3 GREB1 CEMIP	4.10e-05	185	92	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 TMEM178A FMN1 CRYBG1 ELF3	4.21e-05	186	92	5	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 BNC2 RIPOR3 SLC45A2 NRP1	4.31e-05	187	92	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	BNC2 COL27A1 SLC2A2 ADCY9 NRP1	4.31e-05	187	92	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK3 RARRES1 COL27A1 GREB1 SLC30A10	4.31e-05	187	92	5	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 BNC2 RIPOR3 SLC45A2 NRP1	4.42e-05	188	92	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	DOCK3 BNC2 RARRES1 COL27A1 SLC30A10	4.54e-05	189	92	5	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DPY19L2 TMEM178A FMN1 CRYBG1	4.65e-05	190	92	5	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NBEAL2 FER HIP1R CRYBG1 ELF3	4.77e-05	191	92	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 BNC2 FMN1 TRPM2 ITGA4	4.77e-05	191	92	5	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	KIDINS220 HMGCR PRKDC ITGA4 LYST	4.77e-05	191	92	5	9454f642c3621370fa23640b631301346b300950
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 IL11 ELF3 NRP1	4.77e-05	191	92	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 IL11 ELF3 NRP1	4.77e-05	191	92	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	BNC2 CORO2B RARRES1 CATSPERB RIPOR3	4.89e-05	192	92	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPY19L2 FMN1 FIBCD1 ANO8	4.90e-05	97	92	4	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPY19L2 FMN1 FIBCD1 ANO8	4.90e-05	97	92	4	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIP1R ANO7 ELF3 ERN2 PIGZ	5.01e-05	193	92	5	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HIP1R ANO7 ELF3 ERN2 PIGZ	5.01e-05	193	92	5	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIGQ DPY19L2 TMEM178A HIP1R CRYBG1	5.01e-05	193	92	5	d994b2f2707877288f88cab7cd6002ef91962c50
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 CORO2B RARRES1 CATSPERB RIPOR3	5.01e-05	193	92	5	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 NBEAL2 FER CRYBG1 ELF3	5.14e-05	194	92	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 NBEAL2 FER CRYBG1 ELF3	5.14e-05	194	92	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TANC2 FASN CATSPERB ELF3 ADCY9	5.14e-05	194	92	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TANC2 FASN CELSR1 ELF3 LRG1	5.52e-05	197	92	5	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FASN RARRES1 NBEAL2 ELF3 ERN2	5.52e-05	197	92	5	e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANKRD65 CELSR1 TMEM178A NBEAL2 ELF3	5.52e-05	197	92	5	4ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FASN RARRES1 NBEAL2 ELF3 ERN2	5.52e-05	197	92	5	19cf283537c853fa902852e7b8ac1139729a931a
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK3 FMN1 TRPM2 HTRA4 LILRB4	5.66e-05	198	92	5	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	5'-Adult-Distal_Rectal-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FASN RARRES1 NBEAL2 ELF3 ERN2	5.66e-05	198	92	5	9c0535099750698daac5d6b4d39fb19fecf4ffde
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIGQ IL11 DPY19L2 TMEM178A HIP1R	5.79e-05	199	92	5	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 RARRES1 COL27A1 ELF3 NRP1	5.93e-05	200	92	5	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	PND07-28-samps-Lymphocyte-B_cell-B_cell_2\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ZMYND19 TRPM5 TK2 ANKDD1B	1.87e-04	137	92	4	2544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCell	PND07-28-samps-Lymphocyte-B_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ZMYND19 TRPM5 TK2 ANKDD1B	1.87e-04	137	92	4	874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAAT CREB3L3 SLC30A10 SLC2A2	1.97e-04	139	92	4	82bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAAT CREB3L3 SLC30A10 SLC2A2	1.97e-04	139	92	4	fc9ac09c2106e88104a52575832d71d17765eec8
ToppCell	facs-Liver-Hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAAT CREB3L3 SLC30A10 SLC2A2	1.97e-04	139	92	4	fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAAT CREB3L3 SLC30A10 SLC2A2	1.97e-04	139	92	4	4ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIGQ TRPM2 LRG1 LILRB4	2.57e-04	149	92	4	4de52569611e63a780cde9bd111d6d9c11a05a11
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIGQ TRPM2 LRG1 LILRB4	2.57e-04	149	92	4	c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HTRA4 CSNK2A3 CCDC191 CEMIP	2.71e-04	151	92	4	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HTRA4 CSNK2A3 CCDC191 CEMIP	2.71e-04	151	92	4	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-stem_cells_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	DOCK3 ANO7 EDEM1 SLC30A2	2.78e-04	152	92	4	375c9ef88c7703a002e868645a722c35e046ef1e
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM2 LYST LRG1 LILRB4	2.85e-04	153	92	4	ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM5 DPY19L2 TMEM178A CRYBG1	2.85e-04	153	92	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM2 LYST LRG1 LILRB4	2.85e-04	153	92	4	9dba38574908f31a1194b8a339868f5e4be1be71
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO2B TRPM5 COL27A1 ANO7	3.07e-04	156	92	4	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L2 FMN1 SLC45A2 HMGCLL1	3.07e-04	156	92	4	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM5 DPY19L2 TMEM178A CRYBG1	3.14e-04	157	92	4	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZMYND19 POLRMT ELF3 ANO8	3.14e-04	157	92	4	abfd05ed993b80822739f47a735f154092a23632
ToppCell	Club_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	BAAT ELF3 GREB1 ERN2	3.37e-04	160	92	4	b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 LYST LRG1 LILRB4	3.45e-04	161	92	4	e227f7b711475624cf80e77f235b1783d88d57b4
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 LYST LRG1 LILRB4	3.45e-04	161	92	4	8280a029026c272cae9649b27575831b0dd4e242
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM2 LYST LRG1 LILRB4	3.54e-04	162	92	4	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM2 LYST LRG1 LILRB4	3.54e-04	162	92	4	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO2B TRPM5 COL27A1 ANO7	3.54e-04	162	92	4	ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TIMELESS HTRA4 ANO8 LILRB4	3.70e-04	164	92	4	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 RIPOR3 LYST LILRB4	3.70e-04	164	92	4	8e6dbddacd56a07769163813e3ebfad13302bb62
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TIMELESS HTRA4 ANO8 LILRB4	3.70e-04	164	92	4	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tox_(Neuron.Slc17a7.Syt6-Tox)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRIM72 SLC45A2 CEACAM20	3.77e-04	68	92	3	b8d472ff47312a8cc8ba60809947c82f4054d8de
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Tox_(Neuron.Slc17a7.Syt6-Tox)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRIM72 SLC45A2 CEACAM20	3.77e-04	68	92	3	94acd088e39a17cd573aa3ad533b6634e3b7018d
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Syt6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRIM72 SLC45A2 CEACAM20	3.77e-04	68	92	3	89929e9e3a119f6eafef37a401e8fe2bd972452b
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 GREB1 HMGCLL1 ANO8	3.79e-04	165	92	4	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OVGP1 GREB1 HMGCLL1 ANO8	3.79e-04	165	92	4	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TRIM72 TRPM5 CEACAM20	3.93e-04	69	92	3	4831573a45ace5f06cd409f0e75bce838ed65a88
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 RARRES1 PLXNB3 CEMIP	3.97e-04	167	92	4	743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELSR1 OVGP1 TOPBP1 RIPOR3	3.97e-04	167	92	4	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	CELSR1 CATSPERB ELF3 ERN2	3.97e-04	167	92	4	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 RARRES1 PLXNB3 CEMIP	3.97e-04	167	92	4	1adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TANC2 TRPM5 COL27A1 HIP1R	4.06e-04	168	92	4	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 PIGZ PLXNB3 ANO8	4.06e-04	168	92	4	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 LYST LRG1 LILRB4	4.15e-04	169	92	4	a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCell	facs-BAT-Fat-18m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 LYST LRG1 LILRB4	4.15e-04	169	92	4	d3e6c75e5eda133fb6535cfe6c6a1026641f26ac
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO2B TRPM5 HIP1R ELF3	4.15e-04	169	92	4	05e12524d68d409fed386ffad233305683b4575b
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 LYST LRG1 LILRB4	4.15e-04	169	92	4	e0076aa61b4ef3f836f5750005d0469d3982eb6d
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; PC3; HT_HG-U133A	IL11 CELSR1 TK2 NBEAL2 ANAPC2 TMEM132A HIP1R CEMIP	1.25e-06	197	91	8	7273_DN
Disease	Spastic Paraplegia	HACE1 LYST	3.05e-04	9	87	2	C0037772
Disease	lobe attachment	BNC2 FMN1 CRYBG1 PRKDC NRP1	3.75e-04	207	87	5	EFO_0007667
Disease	Umbilical hernia	FMN1 SLC30A10	4.65e-04	11	87	2	HP_0001537
Disease	placenta growth factor measurement	RPS6KL1 NRP1	4.65e-04	11	87	2	EFO_0010626
Disease	actinic keratosis	BNC2 SLC45A2	7.64e-04	14	87	2	EFO_0002496
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ANKDD1B SPG11 HMGCR CEACAM20	8.85e-04	144	87	4	EFO_0004611, EFO_0020943
Disease	apolipoprotein A 1 measurement	CSNK2A1 EIF2B4 FER HIP1R SPG11 CREB3L3 ARID1A SLC30A10 NRP1	8.89e-04	848	87	9	EFO_0004614
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ANKDD1B SPG11 HMGCR CEACAM20	1.03e-03	150	87	4	EFO_0004611, EFO_0020947
Disease	Liver diseases	IL11 IL9R NRP1	1.27e-03	72	87	3	C0023895
Disease	Liver Dysfunction	IL11 IL9R NRP1	1.27e-03	72	87	3	C0086565
Disease	nevus count	FMN1 SLC45A2	1.28e-03	18	87	2	EFO_0004632
Disease	freckles	BNC2 SLC45A2	1.58e-03	20	87	2	EFO_0003963
Disease	skin aging measurement	BNC2 KIDINS220 FMN1 SLC45A2	2.05e-03	181	87	4	EFO_0008006
Disease	C-reactive protein measurement	DOCK3 BNC2 EIF2B4 BAAT RIPOR3 SPG11 CREB3L3 CEACAM20 SLC2A2 ADCY9	2.89e-03	1206	87	10	EFO_0004458

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTHDLRLHWGGEVIP	BAAT	376	Q14032
EVSWLHGLKALGHLD	LRG1	156	P02750
VLRGHGLHSVLEEWF	ANAPC2	61	Q9UJX6
AAVEEWLVRITLHHG	CATSPERB	126	Q9H7T0
ILRHVELGEGWGHVK	CREB3L3	36	Q68CJ9
EVLHILHGLGWTLRD	BNC2	201	Q6ZN30
HLGEQLIIRALTWEH	CEACAM20	396	Q6UY09
VIGSWTDHLHLRIER	GRM4	491	Q14833
RGTHLWEFIRDILIH	ELF3	271	P78545
GLRVTDGEWHHLLIE	CELSR1	1766	Q9NYQ6
VSWHLLHEVLTGRTL	AGO3	131	Q9H9G7
ERSWGHRGVIVHVID	CEMIP	181	Q8WUJ3
DDHTLLWLLNHIRVG	ANO8	76	Q9HCE9
HDIITLLGVGGHWVT	CRYZL1	246	O95825
LVATSDGLLHLIHWE	RIC1	156	Q4ADV7
IENLKHELEHRWRGG	FMN1	766	Q68DA7
LLHWRIGGGDTTEHI	ARID1A	1841	O14497
DIGIWFHILAGLTHL	ANO7	761	Q6IWH7
IIWAAGRGHADIVHL	KIDINS220	141	Q9ULH0
LLHVWHSGVLLELGL	GREB1	711	Q4ZG55
HSGLRRHWEVLIGVL	LILRB4	251	Q8NHJ6
LRHGIGHIEAIFLKW	KCNK4	146	Q9NYG8
SLGLVLVHAHSRWIA	HMGCR	261	P04035
DTLHFLALRWGHIRL	ERN2	251	Q76MJ5
GLAVKEWLLAHEGHR	MGMT	161	P16455
AILGGLHLTLDWAVR	IL11	176	P20809
VHALDLEWRSGLAGH	PLXNB3	1571	Q9ULL4
GTLLVLIWNDHSLHE	OR51B4	41	Q9Y5P0
HWLAVNGRTELLHDL	HACE1	136	Q8IYU2
DLWHILLGLSGVRAI	SLC2A2	216	P11168
THWLEHIKLILAGAL	MTMR2	386	Q13614
WHGHSRVAELLLQRG	ANKRD65	116	E5RJM6
GIAVFVAILHWLHLV	DPY19L2	111	Q6NUT2
HLVESWDLRSGLLHV	MROH1	1436	Q8NDA8
WLEGRHTLRSLVHAG	EIF2B4	366	Q9UI10
AIHHLHEEWLIKGSL	TK2	211	O00142
HGTRGELLLDVAWHP	RBBP5	291	Q15291
IGHQGDHWKEGRVLL	NRP1	756	O14786
HEHRKLRLIDWGLAE	CSNK2A3	166	Q8NEV1
NIREIGDLWGHLHDR	HIP1R	111	O75146
VVHVQLWGRLLHGSR	HTRA4	181	P83105
LELHGHSRRVGLVEW	CORO2B	131	Q9UQ03
GVLLLDHDGGFWLVH	DNASE2	116	O00115
ITVRLDWGNEHLGLD	DOCK3	146	Q8IZD9
WILSHEDVILGELLG	FER	556	P16591
HWHGAELLKRELALT	CCDC191	411	Q8NCU4
ALHWELLSRGLLHGC	ADCY9	276	O60503
WHHLALELRGRTVTL	COL27A1	156	Q8IZC6
HEHRKLRLIDWGLAE	CSNK2A1	166	P68400
LHGLRVHSWVLVLSG	DRC7	296	Q8IY82
GHIVSVDEHLRELPW	EDEM1	581	Q92611
LRLWTVNGDLVGHVH	LYST	3686	Q99698
VVLHSHGANRWLLVG	ITGA4	56	P13612
GEHWLGLKRIHALTT	FIBCD1	311	Q8N539
LHSIRWLRVILDEGH	HLTF	546	Q14527
LSGLWGIEDILERHE	CRYBG1	1086	Q9Y4K1
LRILIVDWDVHHGNG	HDAC6	641	Q9UBN7
HVLWHTGGKGVDLVL	FASN	1731	P49327
ISLATEWLVGEHRAH	SLC22A14	256	Q9Y267
EWLVGEHRAHAIILG	SLC22A14	261	Q9Y267
LLGAIDWAHLELGRL	SLC45A2	196	Q9UMX9
HGLDWLKIHLVNLTG	POLRMT	836	O00411
LWVGLVLVLKHHDGA	OVGP1	6	Q12889
LVGIPGLEHLHAWIS	OR52K1	16	Q8NGK4
QLLREHLWIGDSVAG	HMGCLL1	16	Q8TB92
THLLGPDWLLDVSHL	TMEM132A	566	Q24JP5
DEWHLLHLRRITAGF	TMEM178A	166	Q8NBL3
HGLDGRLTGHRVETW	NBEAL2	866	Q6ZNJ1
MLLSWLHGRSRIGHL	PIGQ	291	Q9BRB3
RQGHWQIVDLLLTHG	TANC2	1076	Q9HCD6
VLHWLAKHGRHEELI	SOWAHD	151	A6NJG2
QHRDHIVGVTWLILE	IL9R	196	Q01113
EHGHRALLIWLHGTL	ANKDD1B	471	A6NHY2
DDLGVTWHHGRLIRP	NEU3	206	Q9UQ49
ERHLLLTLAGHWLAQ	SPG11	1771	Q96JI7
HDQLLWAIHLSGLDD	TIMELESS	186	Q9UNS1
HIWELVSGKIIATLH	SLC30A10	336	Q6XR72
RLLHELLWERHRGGV	ZMYND19	66	Q96E35
LVTLGDHDGRTLALW	WDR90	1221	Q96KV7
TQALLHPHDGRLEWI	TRPM5	891	Q9NZQ8
WLIEGALEVHLGEFH	RIPOR3	191	Q96MK2
VATWGTVHRREGLIH	TRPM2	241	O94759
HGIHGILHLLREIEW	TTC41P	1091	Q6P2S7
HLEHVQGGTLWSHLL	RPS6KL1	216	Q9Y6S9
WLLGLREGKILEAHV	TRIM72	381	Q6ZMU5
SGAWRDHLSLHIVEL	PIGZ	561	Q86VD9
HHEWVVKESGILVLG	TNPO1	416	Q92973
ICISHWILGIGDRHL	PRKDC	3911	P78527
LAHLAAWGLVGLHNI	USP41	46	Q3LFD5
HGHIDPSLRLIWDLA	RARRES1	181	P49788
VKERGVHIVSEHWLL	TOPBP1	961	Q92547
VTAHEDGHLRLWTLE	WDR64	786	B1ANS9
LSVEGVEALHSLHIW	SLC30A2	246	Q9BRI3
HHLLREWGEELQAVL	GEMIN4	321	P57678