Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC22A6 SLC7A5 SLC13A1 NDUFB1 SLC17A1 SLC25A2 UQCRFS1P1

6.50e-05477437GO:0022804
GeneOntologyMolecularFunctionpalmitoyltransferase activity

GLUL ZDHHC6 HHAT

6.87e-0537433GO:0016409
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC22A6 SLC7A5 SLC13A1 SLC17A1 SLC25A2

4.20e-04296435GO:0015291
GeneOntologyMolecularFunctionmonoacylglycerol lipase activity

LIPC ABHD12B

5.33e-0416432GO:0047372
GeneOntologyMolecularFunctionserine-type endopeptidase activity

MST1L KLK13 KLKB1 GZMM

7.33e-04190434GO:0004252
GeneOntologyMolecularFunctiontransmembrane transporter activity

KCNAB1 SLC22A6 SLC7A5 SLC13A1 NDUFB1 SLC17A1 SLC25A2 UQCRFS1P1 SLC52A3

7.75e-041180439GO:0022857
GeneOntologyMolecularFunctionserine-type peptidase activity

MST1L KLK13 KLKB1 GZMM

1.01e-03207434GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

MST1L KLK13 KLKB1 GZMM

1.10e-03212434GO:0017171
GeneOntologyMolecularFunctionprotein-cysteine S-palmitoyltransferase activity

GLUL ZDHHC6

1.42e-0326432GO:0019706
GeneOntologyMolecularFunctionprotein-cysteine S-acyltransferase activity

GLUL ZDHHC6

1.42e-0326432GO:0019707
GeneOntologyMolecularFunctiontransporter activity

KCNAB1 SLC22A6 SLC7A5 SLC13A1 NDUFB1 SLC17A1 SLC25A2 UQCRFS1P1 SLC52A3

1.45e-031289439GO:0005215
GeneOntologyMolecularFunctionhistone kinase activity

MST1L HIPK4

1.65e-0328432GO:0035173
GeneOntologyMolecularFunctionlysophospholipase activity

LIPC ABHD12B

1.77e-0329432GO:0004622
GeneOntologyMolecularFunctionS-acyltransferase activity

GLUL ZDHHC6

1.90e-0330432GO:0016417
GeneOntologyMolecularFunctionantiporter activity

SLC22A6 SLC7A5 SLC25A2

3.26e-03138433GO:0015297
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC22A6 SLC7A5 SLC25A2 SLC52A3

3.57e-03293434GO:0008514
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC13A1 NDUFB1 SLC17A1 UQCRFS1P1

3.93e-03301434GO:0022853
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

KCNAB1 SLC22A6 SLC13A1 NDUFB1 SLC17A1 UQCRFS1P1

5.40e-03758436GO:0015318
DomainPAN

MST1L KLKB1

9.81e-057412PS50948
DomainPan_app

MST1L KLKB1

9.81e-057412IPR003609
DomainPAN_1

MST1L KLKB1

9.81e-057412PF00024
DomainPeptidase_S1A

MST1L KLK13 KLKB1 GZMM

1.08e-04113414IPR001314
DomainTRYPSIN_DOM

MST1L KLK13 KLKB1 GZMM

1.16e-04115414PS50240
DomainTryp_SPc

MST1L KLK13 KLKB1 GZMM

1.24e-04117414SM00020
DomainTrypsin

MST1L KLK13 KLKB1 GZMM

1.41e-04121414PF00089
DomainTrypsin_dom

MST1L KLK13 KLKB1 GZMM

1.41e-04121414IPR001254
DomainPeptidase_S1_PA

MST1L KLK13 KLKB1 GZMM

1.50e-04123414IPR009003
DomainTRYPSIN_SER

KLK13 KLKB1 GZMM

1.01e-0390413IPR033116
DomainTRYPSIN_HIS

KLK13 KLKB1 GZMM

1.49e-03103413IPR018114
DomainTRYPSIN_SER

KLK13 KLKB1 GZMM

1.62e-03106413PS00135
DomainTRYPSIN_HIS

KLK13 KLKB1 GZMM

1.66e-03107413PS00134
Pubmed

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

LIPC PHF23 KLKB1

2.57e-054643322286219
Pubmed

Atlas of gene expression in the developing kidney at microanatomic resolution.

SLC22A6 TSPAN18 FGF19

4.18e-055443319000842
Pubmed

An atlas of genetic influences on human blood metabolites.

SLC7A5 LIPC SLC17A1 KLKB1

9.01e-0519043424816252
Pubmed

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.

GLUL NTRK3

9.78e-051243216537434
Pubmed

Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.

LIPC FCER1A

1.77e-041643220691829
Pubmed

Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.

FCER1A KLKB1

2.01e-041743219372141
Pubmed

Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.

LIPC FGF19

2.52e-041943237541847
Pubmed

Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling.

GLUL FGF19

2.52e-041943226911688
Pubmed

Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.

LPAR3 LIPC SLC13A1

3.28e-0410843331202927
Pubmed

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.

KLK13 KLKB1

4.05e-042443215331780
Pubmed

Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes.

NTRK3 OPRD1

5.53e-042843227076431
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PHTF2 SMYD4 MST1L CYFIP1 PTH2R DENND4C SLC52A3

7.61e-04124243730973865
Pubmed

The transcription factor RBP-J is essential for retinal cell differentiation and lamination.

GLUL FGF19

8.17e-043443220017954
Pubmed

Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

LXN NTRK3

8.66e-043543218498732
Pubmed

Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.

LXN NTRK3

9.67e-043743218498735
Pubmed

The genetic architecture of economic and political preferences.

LPAR3 EML6

9.67e-043743222566634
Pubmed

GWAS of dental caries patterns in the permanent dentition.

PHTF2 LPAR3

1.19e-034143223064961
Pubmed

Individual retinal progenitor cells display extensive heterogeneity of gene expression.

GLUL FGF19

1.19e-034143218270576
Cytoband11p11.2

OR4C3 TSPAN18

2.78e-038343211p11.2
GeneFamilySolute carriers

SLC22A6 SLC7A5 SLC13A1 SLC17A1 SLC25A2 SLC52A3

2.62e-05395286752
GeneFamilyKallikreins

KLK13 KLKB1

2.74e-0416282616
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_200

SLC22A6 LPAR3 SLC13A1 SLC17A1 SLC52A3

9.16e-06151405gudmap_developingKidney_e15.5_early proxim tubul_200
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_500

SLC22A6 LPAR3 TSPAN18 SLC13A1 SLC17A1 SLC52A3

8.72e-05393406gudmap_developingKidney_e15.5_early proxim tubul_500
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

TM7SF2 SLC22A6 LPAR3 LIPC TSPAN18 SLC13A1 SLC17A1 SLC52A3

8.97e-05784408gudmap_developingKidney_e15.5_early proxim tubul_1000
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

8.60e-071864258287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

8.83e-0718742571eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

9.30e-0718942513fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

9.30e-07189425204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

9.80e-071914253c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 TSPAN18 SLC13A1 SLC17A1 PTH2R

9.80e-071914251c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellCOVID-19-kidney-Epithelial_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

LIPC SLC13A1 SLC17A1 PTH2R

4.82e-061194247cde7c73bb71f5e1911706e51c2ea6dcc72930ac
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCNAB1 LYPD6 SLC25A2 OPRD1

1.05e-051454248b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCellTCGA-Kidney|World / Sample_Type by Project: Shred V9

SLC22A6 SLC13A1 SLC17A1 PTH2R

1.24e-05151424e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCell356C-Myeloid-Dendritic-pDC|356C / Donor, Lineage, Cell class and subclass (all cells)

SLC7A5 FCER1A ABHD12B HHAT

1.40e-05156424d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1 ENTPD4

1.79e-051664248ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1 ENTPD4

1.88e-05168424dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1 SLC25A2

1.92e-05169424daed9083ee05c220365200328c2c50047fe21efd
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

SLC7A5 ABHD12B GZMM NCR3

1.92e-051694246d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCellInfluenza_Severe-gd_T|Influenza_Severe / Disease group and Cell class

SLC7A5 ABHD12B GZMM NCR3

1.97e-0517042459009c5a504ea8c6b4f6697299db219fd5edf7d6
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.36e-0517842423a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.41e-0517942458ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.46e-05180424f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL SLC22A6 SLC13A1 SLC17A1

2.46e-05180424b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.46e-05180424864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.46e-05180424358923e4228035a3e90e2957392089219e90dcd7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.46e-051804241363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.52e-051814249542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.52e-051814248f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL SLC22A6 SLC13A1 SLC17A1

2.52e-05181424bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL SLC22A6 SLC13A1 SLC17A1

2.52e-05181424cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.52e-051814246980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.63e-05183424facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.63e-0518342484b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.68e-05184424dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.74e-051854241bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.80e-05186424f28d72b47624b69a580b4429e2be560a26898591
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.80e-05186424b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.86e-05187424d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.86e-051874249d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.86e-05187424f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.86e-05187424d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.86e-05187424738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.86e-051874243ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.86e-05187424dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Cytotoxic_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GLUL SLC7A5 GZMM NCR3

2.92e-05188424c80956649b10b7dd7540394a00fc2a0619b27e80
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.92e-05188424f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A6 SLC13A1 SLC17A1 PTH2R

2.92e-051884240792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.98e-0518942428b502611829e4a24caff2562545c7db97686099
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TSPAN18 SLC13A1 SLC17A1 PTH2R

2.98e-051894240be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN18 SLC13A1 SLC17A1 PTH2R

3.04e-05190424989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellSepsis-URO-Lymphocyte-T/NK-MAIT|URO / Disease, condition lineage and cell class

SLC7A5 HHAT GZMM NCR3

3.57e-0519842475db638278d4be2b0f406cd8871058a8352c5a86
ToppCellBAL-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

PHTF2 FCER1A TM6SF1 UFC1

3.64e-05199424da180aaa53f995183522da0f2321bf0c0c8ee6ec
ToppCell(7)_Mast_cell|World / shred on Cell_type and subtype

GLUL FCER1A LXN TM6SF1

3.64e-05199424c0b5f1cb435da99a7e2ebac9ee7d7b1bd0e49b42
ToppCellTransverse-(7)_Mast_cell-(70)_Mast|Transverse / shred on region, Cell_type, and subtype

GLUL FCER1A LXN TM6SF1

3.72e-05200424aa17354c83b0967707d995e4b74e042ac211f814
ToppCellTransverse-Mast_cell-Mast|Transverse / Region, Cell class and subclass

GLUL FCER1A LXN TM6SF1

3.72e-052004240af942a33cc50da65129204976e24203320e206d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL SLC22A6 LPAR3 KLKB1

3.72e-0520042407d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL SLC22A6 LPAR3 KLKB1

3.72e-05200424d0812817ef99608994193787a62d39adeb2070ca
ToppCellTransverse-Mast_cell|Transverse / Region, Cell class and subclass

GLUL FCER1A LXN TM6SF1

3.72e-052004245e3f5349ffbcabdca3d911fbc99a46aaa56c47c4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLUL SLC22A6 LPAR3 KLKB1

3.72e-05200424cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellTransverse-(7)_Mast_cell|Transverse / shred on region, Cell_type, and subtype

GLUL FCER1A LXN TM6SF1

3.72e-05200424d90d1d3015a9258298bd6b4ba07971aa1af8b82b
ToppCell(70)_Mast|World / shred on Cell_type and subtype

GLUL FCER1A LXN TM6SF1

3.94e-05203424b7af2130b4965661b5a50717a7f82d8d498f8d08
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYPD6 TM6SF1 OPRD1

2.66e-04133423fc319644868078ea0f88a71d55f5e858c6848b50
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYPD6 TM6SF1 OPRD1

2.78e-0413542354b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM7SF2 LIPC KLKB1

3.03e-0413942382bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCellfacs-Liver-Hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM7SF2 LIPC KLKB1

3.03e-04139423fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM7SF2 LIPC KLKB1

3.03e-041394234ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM7SF2 LIPC KLKB1

3.03e-04139423fc9ac09c2106e88104a52575832d71d17765eec8
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LPAR3 KLK13 SLC52A3

3.30e-0414342328e936c298a45f88d14f0146caf3d5a22d483cd5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYPD6 TM6SF1 OPRD1

3.50e-0414642310839a4fce2e62955a90592f927a6e0c6a84bbad
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYPD6 TM6SF1 OPRD1

3.72e-041494231e77f03d2b32f366018fec3462d1b75f6e7febb9
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

OPRD1 GZMM NCR3

3.72e-0414942395b21d67d6c335330a508f78d5cc074fdaf92275
ToppCellfacs-Aorta-Heart-24m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1

3.94e-041524231da25f913b0fb167f66e539aef509ca44893a878
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNAB1 LPAR3 NTRK3

3.94e-04152423ee329249a034a969a16b26a224aa04249d67382d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNAB1 LPAR3 NTRK3

3.94e-04152423bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1

3.94e-04152423254f92d9e6c9c6404f3875dd54d655af87854b14
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A6 SLC13A1 SLC17A1

4.09e-0415442389a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A6 SLC13A1 SLC17A1

4.09e-04154423f1fea1a87e977221fa125b62287368be9af4987d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYPD6 TM6SF1 OPRD1

4.09e-04154423a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_CTL|Leuk-UTI / Disease, Lineage and Cell Type

HIPK4 ABHD12B GZMM

4.09e-04154423170a421fd69dba2929568c72e983ae9cfaf2aabc
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A6 SLC13A1 SLC17A1

4.09e-04154423b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A6 SLC13A1 SLC17A1

4.09e-04154423160b170a3ade8b246843c9854af332475c047ba0
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SLC7A5 KLKB1 EML6

4.17e-04155423c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM7SF2 LIPC KLKB1

4.25e-04156423e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellsevere_COVID-19-cDC|World / disease group, cell group and cell class (v2)

FCER1A KLKB1 OPRD1

4.25e-041564230a7e18ed8e13261c405eb6b9a183e99d8e1aac37
ToppCellASK452-Epithelial-Type_2|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ABHD12B PHF23 HHAT

4.25e-04156423e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

FCER1A KLKB1 OPRD1

4.33e-04157423ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCellsevere_influenza-NK_CD56bright|severe_influenza / disease group, cell group and cell class (v2)

LIPC GZMM NCR3

4.33e-04157423fabaf54429dd5a899f9192f0d42522109ca36b9b
ToppCellsevere_COVID-19-MAIT|severe_COVID-19 / disease group, cell group and cell class (v2)

SLC7A5 GZMM NCR3

4.33e-04157423175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TM7SF2 LXN NCR3

4.41e-041584234d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNAB1 GZMM NCR3

4.49e-04159423235ed12053b337aca5abc2ce8727332b4ae3f8ae
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1

4.49e-04159423c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PHTF2 LIPC ABHD12B

4.49e-04159423ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC7A5 FCER1A PHF23

4.58e-041604236393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC7A5 FCER1A PHF23

4.58e-041604232065938e944eb99478fd8132c2c03adeaee6d447
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

SLC7A5 ABHD12B GZMM

4.66e-04161423b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|367C / Donor, Lineage, Cell class and subclass (all cells)

PTH2R GZMM NCR3

4.66e-04161423f7dc1e3326ab22f2eb1e94b632469a0682a3289c
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLUL KCNAB1 OPRD1

4.83e-04163423240d9f0ea45e8b2c7173e7674fd740555810f9e7
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

SLC7A5 HHAT NCR3

4.92e-04164423cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PHTF2 KCNAB1 HIPK4

5.01e-04165423e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A6 SLC13A1 SLC17A1

5.01e-04165423082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PHTF2 KCNAB1 HIPK4

5.01e-04165423b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNAB1 NTRK3 NCR3

5.01e-04165423cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC7A5 GZMM NCR3

5.01e-041654235e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PHTF2 KCNAB1 HIPK4

5.01e-04165423d8f8b088fd28a6b9dbd6b51bcaee42000e963321
Diseasetemporal lobe epilepsy (is_marker_for)

GLUL CYFIP1

3.70e-0420422DOID:3328 (is_marker_for)
Diseaseinflammatory bowel disease (implicated_via_orthology)

MST1L KLKB1

5.81e-0425422DOID:0050589 (implicated_via_orthology)
Diseaseandrosterone sulfate measurement

SLC17A1 NTRK3

1.02e-0333422EFO_0021117
Diseaseserum metabolite measurement

SLC7A5 LIPC TSPAN18 SLC17A1 KLKB1 HHAT

2.08e-03945426EFO_0005653
Diseasedental caries

PHTF2 LPAR3 KLKB1

2.40e-03187423EFO_0003819
Diseasephenylalanine measurement

SLC17A1 KLKB1

2.80e-0355422EFO_0005001

Protein segments in the cluster

PeptideGeneStartEntry
VVMEGQPLFLRCHGW

FCER1A

121

P12319
CGGVLVHPKWVLTAA

GZMM

51

P51124
GVMLGIWHTVPSCRG

ABHD12B

106

Q7Z5M8
CGGVLVHPKWVLTAA

KLK13

61

Q9UKR3
GLHWAGCMIIVLLGQ

CYFIP1

1156

Q7L576
TWMIGCVHAMILTPL

OR10D4P

146

Q8NGN7
LLILIMVHPGSCALW

NCR3

6

O14931
CIWCEVGGHTMLPIR

NTRK3

721

Q16288
LGCVMAELHLGWPLY

HIPK4

201

Q8NE63
CHMPLTGYEVWLGTL

MST1L

531

Q2TV78
HKIGVGAMTWSPLAC

KCNAB1

286

Q14722
WPGVLKVVSGCHISL

KIAA1109

4626

Q2LD37
MRSGCVVVHVWILAG

FGF19

1

O95750
GVMSWIIPVFVGLSC

SLC7A5

321

Q01650
LPLVMIIHGWSVDGV

LIPC

81

P11150
VMTVLGAFVVCWTPG

LPAR3

241

Q9UBY5
CIWVLASGVGVPIMV

OPRD1

171

P41143
IMALAWSLPCGVSHL

TM7SF2

356

O76062
WCVLGTPGVAMVLLH

HHAT

106

Q5VTY9
VMQLCGLWGHPVLAV

DENND4C

826

Q5VZ89
GHPRCMSVIVSCLWL

LYPD6

151

Q86Y78
PLVCKHNGMWRLVGI

KLKB1

581

P03952
PMLILQGHCEGELWA

EML6

316

Q6ZMW3
GVAVVMLGICTWIVP

SLC13A1

561

Q9BZW2
VEWMPIHTRACVGTL

SLC22A6

211

Q4U2R8
IKMSPELLGWTHGLC

OTOG

271

Q6ZRI0
RHLCAMLVGVAWLGG

OR4C3

136

Q8NH37
PEMTLVLHLAWVACG

LXN

131

Q9BS40
IGPCEGISMGDHLWV

GLUL

206

P15104
GPIWLMLLLGTVHCQ

PHTF2

171

Q8N3S3
HLLVCVFGMGSWVTI

SLC52A3

6

Q9NQ40
LCPDVTIWGVAMLRH

SMYD4

481

Q8IYR2
VAHCPKAEVLWLMGA

PRPF6

601

O94906
MGRIGISCLFPASWH

ENTPD4

1

Q9Y227
LLVTGVICESLGWPM

SLC17A1

186

Q14916
HLMLSGGVAGICLWL

SLC25A2

211

Q9BXI2
HWGPIIALGVIAICS

ZDHHC6

21

Q9H6R6
HLMALGLGPWLAVEI

UFC1

136

Q9Y3C8
RPMIECSLCGTWIHL

PHF23

351

Q9BUL5
CLPHSFTGLGWEIRM

PTH2R

381

P49190
HWVHVLVPMGFVIGC

NDUFB1

11

O75438
CLLAIGIWVMVDPTG

TSPAN18

26

Q96SJ8
KPEWVILIGVCTHLG

UQCRFS1P1

216

P0C7P4
CSWMPDITLIHAGGL

TM6SF1

291

Q9BZW5