Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

KIF1A ABCA13 MYO10 MYH7B KIF1B ABCC9 MYO1B BTAF1 XRCC2 ABCA10 ZRANB3 ABCC12 ACSM2A DYNC1H1 ACSM2B

4.52e-0561414615GO:0140657
GeneOntologyMolecularFunctiontransporter activity

CACNA1B TRPM4 MRS2 ABCA13 SLC35C1 GRAMD1A HCN3 ABCC9 SPNS3 PKD1L2 PKDREJ SLC1A3 ABCA10 CLCC1 C2CD2L GJB5 LRP2 LRP6 ABCC12 SLC49A3 SLC25A28 NALF2 CNGA4

6.14e-05128914623GO:0005215
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

1.59e-0431462GO:0018858
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 LRP6

2.00e-04161463GO:0005041
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF1A MYO10 MYH7B KIF1B MYO1B DYNC1H1

2.32e-041181466GO:0003774
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

3.16e-0441462GO:0102391
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1B TRPM4 PKD1L2 PKDREJ NALF2 CNGA4

3.75e-041291466GO:0005262
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1B TRPM4 MRS2 ABCA13 SLC35C1 HCN3 ABCC9 SPNS3 PKD1L2 PKDREJ SLC1A3 ABCA10 CLCC1 GJB5 LRP6 ABCC12 SLC49A3 SLC25A28 NALF2 CNGA4

3.80e-04118014620GO:0022857
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA13 ABCC9 ABCA10 ABCC12

4.50e-04491464GO:0140359
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 LRP6

4.62e-04211463GO:0030228
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B TRPM4 MRS2 HCN3 ABCC9 PKD1L2 PKDREJ SLC1A3 SLC25A28 NALF2 CNGA4

6.33e-0446514611GO:0046873
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1B TRPM4 PKD1L2 PKDREJ NALF2 CNGA4

8.61e-041511466GO:0015085
GeneOntologyCellularComponentaxon

CACNA1B DRD5 COPA KIF1A POLG KIF1B HCN3 ADGRL1 CBARP SYDE1 MAPK8IP3 GDPD5 ADRA2A DST LRP1 LRP2 PLEC DYNC1H1 HTT

1.62e-0589114719GO:0030424
GeneOntologyCellularComponentaxon cytoplasm

KIF1A KIF1B MAPK8IP3 DST DYNC1H1

1.17e-04681475GO:1904115
GeneOntologyCellularComponentneuron projection cytoplasm

KIF1A KIF1B MAPK8IP3 DST DYNC1H1 HTT

1.28e-041101476GO:0120111
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1B TRPM4 DRD5 HTR5A COPA KIF1A MYO10 KIF1B HCN3 ADGRB1 SLC1A3 MAPK8IP3 GDPD5 ADRA2A LRP1 LRP2 LRP6 PLEC CNGA4 DYNC1H1 HTT

1.40e-04122814721GO:0036477
GeneOntologyCellularComponentdistal axon

CACNA1B COPA POLG HCN3 ADGRL1 CBARP MAPK8IP3 GDPD5 ADRA2A LRP1 LRP2

2.62e-0443514711GO:0150034
GeneOntologyCellularComponentneuronal cell body

CACNA1B TRPM4 DRD5 HTR5A COPA KIF1A MYO10 HCN3 SLC1A3 GDPD5 ADRA2A LRP1 LRP6 CNGA4 DYNC1H1 HTT

2.68e-0483514716GO:0043025
GeneOntologyCellularComponentcell body

CACNA1B TRPM4 DRD5 HTR5A COPA KIF1A MYO10 HCN3 SLC1A3 MAPK8IP3 GDPD5 ADRA2A LRP1 LRP6 CNGA4 DYNC1H1 HTT

2.93e-0492914717GO:0044297
GeneOntologyCellularComponentapolipoprotein B mRNA editing enzyme complex

APOBEC3G APOBEC3F

4.84e-0451472GO:0030895
GeneOntologyCellularComponentendocytic vesicle membrane

ENTPD7 TBC1D5 RAPGEF1 KIAA0319 AP2A1 LRP1 LRP2

7.68e-042121477GO:0030666
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ENTPD7 COPA KIF1A ABCA13 SEC24A TBC1D5 KIF1B RAPGEF1 MYO1B CBARP KIAA0319 AP2A1 CLVS2 LRP1 LRP2 LRP6 TMEM163 CNGA4 RAB6A HTT

8.46e-04130714720GO:0030659
GeneOntologyCellularComponentmembrane coat

COPA SEC24A TBC1D5 AP2A1 AP5Z1

9.21e-041061475GO:0030117
GeneOntologyCellularComponentcoated membrane

COPA SEC24A TBC1D5 AP2A1 AP5Z1

9.21e-041061475GO:0048475
GeneOntologyCellularComponentvesicle membrane

ENTPD7 COPA KIF1A ABCA13 SEC24A TBC1D5 KIF1B RAPGEF1 MYO1B CBARP KIAA0319 AP2A1 CLVS2 LRP1 LRP2 LRP6 TMEM163 CNGA4 RAB6A HTT

1.00e-03132514720GO:0012506
GeneOntologyCellularComponentmRNA editing complex

APOBEC3G APOBEC3F

1.01e-0371472GO:0045293
GeneOntologyCellularComponentcoated vesicle

COPA SEC24A TBC1D5 KIAA0319 AP2A1 CLVS2 LRP1 LRP2 HTT

1.03e-033601479GO:0030135
GeneOntologyCellularComponentvesicle coat

COPA SEC24A TBC1D5 AP2A1

1.28e-03671474GO:0030120
GeneOntologyCellularComponentclathrin-coated vesicle

TBC1D5 KIAA0319 AP2A1 CLVS2 LRP1 LRP2 HTT

1.46e-032371477GO:0030136
GeneOntologyCellularComponentgrowth cone

COPA ADGRL1 CBARP MAPK8IP3 GDPD5 LRP1 LRP2

1.77e-032451477GO:0030426
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

KIF1A KIF1B MAPK8IP3 CFAP54 DST DYNC1H1 HTT BRWD1

1.85e-033171478GO:0032838
GeneOntologyCellularComponentsite of polarized growth

COPA ADGRL1 CBARP MAPK8IP3 GDPD5 LRP1 LRP2

2.12e-032531477GO:0030427
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

TBC1D5 KIAA0319 AP2A1 LRP2

2.34e-03791474GO:0030669
GeneOntologyCellularComponentclathrin-coated pit

TBC1D5 AP2A1 LRP1 LRP2

2.45e-03801474GO:0005905
GeneOntologyCellularComponenthemidesmosome

DST PLEC

2.59e-03111472GO:0030056
MousePhenoaxonal spheroids

EPG5 DST TECPR2 AP5Z1

1.09e-05171194MP:0010047
Domain6-blade_b-propeller_TolB-like

APMAP NHLRC3 TECPR2 LRP1 LRP2 LRP6

1.43e-06461456IPR011042
Domain-

EVPL DST PLEC

9.01e-06614533.90.1290.10
DomainPKD/REJ-like

PKD1L2 PKDREJ KIAA0319

9.01e-0661453IPR002859
DomainREJ

PKD1L2 PKDREJ KIAA0319

9.01e-0661453PF02010
Domain-

APMAP NHLRC3 LRP1 LRP2 LRP6

1.23e-053914552.120.10.30
DomainAPC_su10/DOC_dom

HECTD3 CUL9 ZZEF1

1.57e-0571453IPR004939
DomainPlectin

EVPL DST PLEC

1.57e-0571453PF00681
DomainDOC

HECTD3 CUL9 ZZEF1

1.57e-0571453PS51284
DomainANAPC10

HECTD3 CUL9 ZZEF1

1.57e-0571453PF03256
DomainPlectin_repeat

EVPL DST PLEC

1.57e-0571453IPR001101
DomainAPC10

HECTD3 CUL9 ZZEF1

1.57e-0571453SM01337
DomainPLEC

EVPL DST PLEC

1.57e-0571453SM00250
DomainGPS

ADGRB1 ADGRL1 PKD1L2 PKDREJ

1.35e-04341454SM00303
DomainLdl_recept_b

LRP1 LRP2 LRP6

1.57e-04141453PF00058
DomainLDLRB

LRP1 LRP2 LRP6

1.57e-04141453PS51120
DomainGPS

ADGRB1 ADGRL1 PKD1L2 PKDREJ

1.89e-04371454IPR000203
DomainLY

LRP1 LRP2 LRP6

1.95e-04151453SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 LRP6

1.95e-04151453IPR000033
DomainARM-like

NCAPD3 PKP4 CUL9 BTAF1 KATNBL1 HEATR6 AP2A1 AP5Z1 HTT

2.64e-042701459IPR011989
DomainP-loop_NTPase

KIF1A ABCA13 MYO10 MYH7B KIF1B NDST4 ABCC9 MYO1B BTAF1 XRCC2 RAB6B ABCA10 ZRANB3 LRRIQ1 ABCC12 RAB6A DYNC1H1

3.17e-0484814517IPR027417
Domain-

NCAPD3 PKP4 CUL9 BTAF1 HEATR6 AP2A1 AP5Z1 HTT

3.47e-0422214581.25.10.10
DomainKinesin-like_KIF1-typ

KIF1A KIF1B

3.56e-0441452IPR022140
DomainKIF1B

KIF1A KIF1B

3.56e-0441452PF12423
DomainREJ

PKD1L2 PKDREJ

3.56e-0441452PS51111
DomainREJ_dom

PKD1L2 PKDREJ

3.56e-0441452IPR014010
DomainLdl_recept_a

TMPRSS9 LRP1 LRP2 LRP6

4.06e-04451454PF00057
Domain-

TMPRSS9 LRP1 LRP2 LRP6

4.41e-044614544.10.400.10
DomainLDLRA_1

TMPRSS9 LRP1 LRP2 LRP6

5.20e-04481454PS01209
DomainABC_tran

ABCA13 ABCC9 ABCA10 ABCC12

5.20e-04481454PF00005
DomainABC_TRANSPORTER_2

ABCA13 ABCC9 ABCA10 ABCC12

5.20e-04481454PS50893
DomainLDrepeatLR_classA_rpt

TMPRSS9 LRP1 LRP2 LRP6

5.63e-04491454IPR002172
DomainLDLa

TMPRSS9 LRP1 LRP2 LRP6

5.63e-04491454SM00192
DomainABC_TRANSPORTER_1

ABCA13 ABCC9 ABCA10 ABCC12

5.63e-04491454PS00211
DomainLDLRA_2

TMPRSS9 LRP1 LRP2 LRP6

5.63e-04491454PS50068
DomainGal_Lectin

ADGRL1 PKD1L2

5.89e-0451452PF02140
DomainPKD_2

PKD1L2 PKDREJ

5.89e-0451452IPR003915
DomainLectin_gal-bd_dom

ADGRL1 PKD1L2

5.89e-0451452IPR000922
DomainSUEL_LECTIN

ADGRL1 PKD1L2

5.89e-0451452PS50228
DomainABC_transporter-like

ABCA13 ABCC9 ABCA10 ABCC12

6.08e-04501454IPR003439
DomainKinesin_assoc

KIF1A KIF1B

8.80e-0461452PF16183
DomainKinesin-like

KIF1A KIF1B

8.80e-0461452IPR022164
DomainKinesin_assoc

KIF1A KIF1B

8.80e-0461452IPR032405
DomainDUF3694

KIF1A KIF1B

8.80e-0461452PF12473
DomainSpectrin_repeat

EVPL DST PLEC

1.44e-03291453IPR002017
DomainSPEC

EVPL DST PLEC

1.93e-03321453SM00150
DomainSpectrin/alpha-actinin

EVPL DST PLEC

1.93e-03321453IPR018159
DomainHEAT_REPEAT

NCAPD3 BTAF1 HEATR6 HTT

2.15e-03701454PS50077
DomainGPS

ADGRB1 ADGRL1 PKD1L2

2.50e-03351453PF01825
DomainGPS

ADGRB1 ADGRL1 PKD1L2

2.71e-03361453PS50221
DomainGAIN_dom_N

ADGRB1 ADGRL1

3.14e-03111452IPR032471
DomainPKD_channel

PKD1L2 PKDREJ

3.14e-03111452PF08016
DomainGAIN

ADGRB1 ADGRL1

3.14e-03111452PF16489
DomainPKD1_2_channel

PKD1L2 PKDREJ

3.14e-03111452IPR013122
DomainMyosin_head_motor_dom

MYO10 MYH7B MYO1B

3.17e-03381453IPR001609
DomainMYOSIN_MOTOR

MYO10 MYH7B MYO1B

3.17e-03381453PS51456
DomainMyosin_head

MYO10 MYH7B MYO1B

3.17e-03381453PF00063
DomainMYSc

MYO10 MYH7B MYO1B

3.17e-03381453SM00242
DomainIQ

MYO10 MYH7B MYO1B LRRIQ1

3.65e-03811454SM00015
DomainLDLR_class-A_CS

LRP1 LRP2 LRP6

3.67e-03401453IPR023415
DomainABC_A

ABCA13 ABCA10

3.75e-03121452IPR026082
DomainAPOBEC_N

APOBEC3G APOBEC3F

3.75e-03121452PF08210
DomainAPOBEC_N

APOBEC3G APOBEC3F

3.75e-03121452IPR013158
DomainABC_transporter_CS

ABCC9 ABCA10 ABCC12

4.22e-03421453IPR017871
DomainAPOBEC/CMP_deaminase_Zn-bd

APOBEC3G APOBEC3F

5.12e-03141452IPR016192
DomainIQ_motif_EF-hand-BS

MYO10 MYH7B MYO1B LRRIQ1

5.32e-03901454IPR000048
DomainAAA

ABCA13 ABCC9 ABCA10 ABCC12 DYNC1H1

5.34e-031441455SM00382
DomainAAA+_ATPase

ABCA13 ABCC9 ABCA10 ABCC12 DYNC1H1

5.34e-031441455IPR003593
DomainCYT_DCMP_DEAMINASES_2

APOBEC3G APOBEC3F

5.88e-03151452PS51747
DomainIQ

MYO10 MYH7B MYO1B LRRIQ1

5.97e-03931454PS50096
DomainHEAT

NCAPD3 BTAF1 HTT

6.14e-03481453PF02985
DomainTBC

TBC1D5 TBC1D2 TBC1D13

6.50e-03491453SM00164
DomainCYT_DCMP_DEAMINASES_1

APOBEC3G APOBEC3F

7.54e-03171452PS00903
DomainCMP_dCMP_Zn-bd

APOBEC3G APOBEC3F

7.54e-03171452IPR002125
DomainCytidine_deaminase-like

APOBEC3G APOBEC3F

7.54e-03171452IPR016193
DomainAMP-bd_C

ACSM2A ACSM2B

7.54e-03171452IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

7.54e-03171452PF13193
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRPM4 MYO10 POLG NAGLU RAPGEF1 CUL9 ADGRL1 RNF40 BTAF1 MED13L ZZEF1 MAPK8IP3 C2CD2L GDPD5 DST AP2A1 PXN NLE1 POFUT1 PLEC ESPL1 DYNC1H1 HTT

3.88e-1011051492335748872
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1B PKP4 HCN3 ADGRL1 CBARP SLC1A3 MAPK8IP3 C2CD2L DST AP2A1 TMEM163 PLEC HTT

3.84e-093471491317114649
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NCAPD3 COPA KIF1A HECTD3 GRAMD1A POR GALNT12 BTAF1 CLCC1 SPAG5 AP2A1 TVP23C LRP6 POFUT1 ESPL1 ANAPC5 RAB6A DYNC1H1

1.32e-079421491831073040
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

COPA KIF1A POLG KIF1B CUL9 RNF40 MED13L MTMR10 MAPK8IP3 CRYL1 HEATR6 DST AP2A1 LRP1 LRP2 PLEC RAB6A DYNC1H1 BRWD1

2.72e-0612851491935914814
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

COPA CUL9 ANAPC5 DYNC1H1

3.22e-0624149433705438
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

TRPM4 NCAPD3 HECTD3 CUL9 ZZEF1 TRMT6 DST ZRANB1

3.98e-06212149833853758
Pubmed

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

KIF1A KIF1B DYNC1H1

4.25e-068149325818806
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CYP4V2 TRPM4 KIF1A APMAP TBC1D5 POLG KIF1B ADGRL1 BTAF1 XRCC2 RAB6B CLCC1 MAPK8IP3 TECPR2 TTLL11 LRP1 TVP23C PAN3 ZRANB1 HTT

6.13e-0614891492028611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ASXL1 MYO10 KIF1B CUL9 ADGRL1 MED13L EPG5 C2CD2L KIAA0319 DYNC1H1

1.11e-054071491012693553
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2 LRP6

1.24e-0511149324639464
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ASXL1 COPA MYO10 TBC1D2 DST AP5Z1 PLEC NEURL1B DYNC1H1

1.43e-05332149937433992
Pubmed

Cytidine deaminases APOBEC3G and APOBEC3F interact with human immunodeficiency virus type 1 integrase and inhibit proviral DNA formation.

APOBEC3G APOBEC3F

1.82e-052149217428847
Pubmed

Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants.

APOBEC3G APOBEC3F

1.82e-052149226482266
Pubmed

N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease.

CACNA1B HTT

1.82e-052149228391067
Pubmed

Bpag1 localization to actin filaments and to the nucleus is regulated by its N-terminus.

DST PXN

1.82e-052149214576348
Pubmed

Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.

APOBEC3G APOBEC3F

1.82e-052149219944180
Pubmed

Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149223318957
Pubmed

Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149220299747
Pubmed

Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149217522216
Pubmed

Characterization of conserved motifs in HIV-1 Vif required for APOBEC3G and APOBEC3F interaction.

APOBEC3G APOBEC3F

1.82e-052149218619467
Pubmed

Remarkable lethal G-to-A mutations in vif-proficient HIV-1 provirus by individual APOBEC3 proteins in humanized mice.

APOBEC3G APOBEC3F

1.82e-052149220610708
Pubmed

Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55(GAG)) of the virion nucleocapsid proteins.

APOBEC3G APOBEC3F

1.82e-052149219826902
Pubmed

The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain.

APOBEC3G APOBEC3F

1.82e-052149215647250
Pubmed

Atg4b-dependent autophagic flux alleviates Huntington's disease progression.

ATG4B HTT

1.82e-052149223861892
Pubmed

Differential requirement for conserved tryptophans in human immunodeficiency virus type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149216501124
Pubmed

The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.

KIF1A KIF1B

1.82e-05214927539720
Pubmed

HIV-1 Vif: counteracting innate antiretroviral defenses.

APOBEC3G APOBEC3F

1.82e-052149214565218
Pubmed

Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins.

APOBEC3G APOBEC3F

1.82e-052149218367521
Pubmed

Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation.

RAB6B RAB6A

1.82e-052149238830762
Pubmed

Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif.

APOBEC3G APOBEC3F

1.82e-052149219669862
Pubmed

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

APOBEC3G APOBEC3F

1.82e-052149225590131
Pubmed

Identification of a novel WxSLVK motif in the N terminus of human immunodeficiency virus and simian immunodeficiency virus Vif that is critical for APOBEC3G and APOBEC3F neutralization.

APOBEC3G APOBEC3F

1.82e-052149219535447
Pubmed

Comparative analysis of the gene-inactivating potential of retroviral restriction factors APOBEC3F and APOBEC3G.

APOBEC3G APOBEC3F

1.82e-052149226048885
Pubmed

Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif.

APOBEC3G APOBEC3F

1.82e-052149220624919
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

1.82e-052149219634011
Pubmed

ADRA2A polymorphisms and ADHD in adults: possible mediating effect of personality.

DRD5 ADRA2A

1.82e-052149220864182
Pubmed

RNA and DNA binding properties of HIV-1 Vif protein: a fluorescence study.

APOBEC3G APOBEC3F

1.82e-052149217609216
Pubmed

Distinct domains within APOBEC3G and APOBEC3F interact with separate regions of human immunodeficiency virus type 1 Vif.

APOBEC3G APOBEC3F

1.82e-052149219036809
Pubmed

Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets.

APOBEC3G APOBEC3F

1.82e-052149219587057
Pubmed

Biochemical differentiation of APOBEC3F and APOBEC3G proteins associated with HIV-1 life cycle.

APOBEC3G APOBEC3F

1.82e-052149217142455
Pubmed

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins.

APOBEC3G APOBEC3F

1.82e-052149215152192
Pubmed

Human APOBEC3F incorporation into human immunodeficiency virus type 1 particles.

APOBEC3G APOBEC3F

1.82e-052149225038404
Pubmed

Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149224185281
Pubmed

Identification of 81LGxGxxIxW89 and 171EDRW174 domains from human immunodeficiency virus type 1 Vif that regulate APOBEC3G and APOBEC3F neutralizing activity.

APOBEC3G APOBEC3F

1.82e-052149220335268
Pubmed

Positioning of APOBEC3G/F mutational hotspots in the human immunodeficiency virus genome favors reduced recognition by CD8+ T cells.

APOBEC3G APOBEC3F

1.82e-052149224722422
Pubmed

Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149220153011
Pubmed

Mechanism of Enhanced HIV Restriction by Virion Coencapsidated Cytidine Deaminases APOBEC3F and APOBEC3G.

APOBEC3G APOBEC3F

1.82e-052149227881650
Pubmed

APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection.

APOBEC3G APOBEC3F

1.82e-052149217145955
Pubmed

Repression of porcine endogenous retrovirus infection by human APOBEC3 proteins.

APOBEC3G APOBEC3F

1.82e-052149221396348
Pubmed

A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion.

APOBEC3G APOBEC3F

1.82e-052149215054139
Pubmed

Inhibition of hepatitis B virus replication by APOBEC3G.

APOBEC3G APOBEC3F

1.82e-052149215031497
Pubmed

Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus.

APOBEC3G APOBEC3F

1.82e-052149224503066
Pubmed

Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning.

KIF1A HTT

1.82e-052149237431882
Pubmed

APOBEC3 proteins and reverse transcription.

APOBEC3G APOBEC3F

1.82e-052149218262674
Pubmed

Different mutagenic potential of HIV-1 restriction factors APOBEC3G and APOBEC3F is determined by distinct single-stranded DNA scanning mechanisms.

APOBEC3G APOBEC3F

1.82e-052149224651717
Pubmed

Death and the retrovirus.

APOBEC3G APOBEC3F

1.82e-052149214557052
Pubmed

Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function.

APOBEC3G APOBEC3F

1.82e-052149220686027
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

1.82e-052149216521160
Pubmed

Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.

LRP1 LRP6

1.82e-052149226031789
Pubmed

High level of APOBEC3F/3G editing in HIV-2 DNA vif and pol sequences from antiretroviral-naive patients.

APOBEC3G APOBEC3F

1.82e-052149225985400
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

1.82e-052149234445520
Pubmed

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G.

APOBEC3G APOBEC3F

1.82e-052149217121840
Pubmed

Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation.

APOBEC3G APOBEC3F

1.82e-052149224623435
Pubmed

E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure.

APOBEC3G APOBEC3F

1.82e-052149222695298
Pubmed

Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.

APOBEC3G APOBEC3F

1.82e-052149219169351
Pubmed

APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms.

APOBEC3G APOBEC3F

1.82e-052149220219927
Pubmed

Moderate influence of human APOBEC3F on HIV-1 replication in primary lymphocytes.

APOBEC3G APOBEC3F

1.82e-052149220592068
Pubmed

Inhibition of initiation of reverse transcription in HIV-1 by human APOBEC3F.

APOBEC3G APOBEC3F

1.82e-052149217459442
Pubmed

Differential sensitivity of porcine endogenous retrovirus to APOBEC3-mediated inhibition.

APOBEC3G APOBEC3F

1.82e-052149226016442
Pubmed

The HIV-1 central polypurine tract functions as a second line of defense against APOBEC3G/F.

APOBEC3G APOBEC3F

1.82e-052149220844042
Pubmed

Molecular docking analysis of RN18 and VEC5 in A3G-Vif inhibition.

APOBEC3G APOBEC3F

1.82e-052149225489169
Pubmed

Stably expressed APOBEC3F has negligible antiviral activity.

APOBEC3G APOBEC3F

1.82e-052149220702622
Pubmed

Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation.

MYO10 TMEM163

1.82e-052149229229982
Pubmed

T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques.

APOBEC3G APOBEC3F

1.82e-052149223536679
Pubmed

Unusual substitutions in HIV-1 vif from children infected perinatally without progression to AIDS for more than 8 years without therapy.

APOBEC3G APOBEC3F

1.82e-052149223080486
Pubmed

Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors.

APOBEC3G APOBEC3F

1.82e-052149219487726
Pubmed

APOBEC deaminases as cellular antiviral factors: a novel natural host defense mechanism.

APOBEC3G APOBEC3F

1.82e-052149216641889
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

1.82e-052149229948332
Pubmed

Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants.

APOBEC3G APOBEC3F

1.82e-052149218448538
Pubmed

Expression of APOBEC3G/3F and G-to-A hypermutation levels in HIV-1-infected children with different profiles of disease progression.

APOBEC3G APOBEC3F

1.82e-052149221897871
Pubmed

APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.

APOBEC3G APOBEC3F

1.82e-052149218604271
Pubmed

Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F.

APOBEC3G APOBEC3F

1.82e-052149218603011
Pubmed

Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation.

APOBEC3G APOBEC3F

1.82e-052149216940537
Pubmed

Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.

APOBEC3G APOBEC3F

1.82e-052149216460778
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCAPD3 RNF40 ZZEF1 TRMT6 ATG4B DST TECPR2 AP5Z1 MED12L IGSF1 ESPL1

1.90e-055291491114621295
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NCAPD3 HECTD3 TBC1D5 PKP4 SENP3 BTAF1 ZZEF1 SYDE1 SPAG5 FREM2 DST ANAPC5

2.54e-056501491238777146
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2 LRP6

2.71e-0514149317389516
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

COPA APMAP SENP3 MYO1B PSMD13 CLCC1 ATG4B AP2A1 AP5Z1 ANAPC5 DYNC1H1

3.19e-055601491135241646
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

KIF1A MRS2 TBC1D5 PSMD13 ZRANB3 DST AP2A1 LRP2 PLEC ZRANB1

4.60e-054811491028190767
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

COPA APMAP MYO1B PSMD13 ECI1 ZZEF1 SPAG5 EPG5 DST AP2A1 PLEC RAB6A DYNC1H1

4.75e-058071491330575818
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

COPA SEC24A TBC1D5 PKP4 GRAMD1A NAGLU POR MYO1B CBARP PSMD13 MTMR10 CLCC1 PXN LRP6 FBXO33

4.79e-0510491491527880917
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FBXL13 MYO10 LRRIQ1 PLEC ESPL1 HTT

5.18e-05152149634299191
Pubmed

The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H.

APOBEC3G APOBEC3F

5.45e-053149222013041
Pubmed

Enhancing immunity to HIV through APOBEC.

APOBEC3G APOBEC3F

5.45e-053149218846074
Pubmed

Hematologically important mutations: leukocyte adhesion deficiency (first update).

SLC35C1 FERMT3

5.45e-053149222134107
Pubmed

BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.

DST PLEC

5.45e-053149219932097
Pubmed

Rab6 family proteins interact with the dynein light chain protein DYNLRB1.

RAB6B RAB6A

5.45e-053149218044744
Pubmed

HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants.

APOBEC3G APOBEC3F

5.45e-053149224942576
Pubmed

Accessories to the crime: recent advances in HIV accessory protein biology.

APOBEC3G APOBEC3F

5.45e-053149219149995
Pubmed

A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability.

PXN FERMT3

5.45e-053149231537712
InteractionSTYK1 interactions

COPA SEC24A TBC1D5 GRAMD1A MYO1B CBARP CLCC1 DST DEPDC1B

3.01e-061611489int:STYK1
Cytoband20q11

ASXL1 POFUT1

1.56e-046149220q11
GeneFamilyEF-hand domain containing|Plakins

EVPL DST PLEC

7.48e-068943939
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2 LRP6

3.75e-0513943634
GeneFamilyCyclic nucleotide gated channels

HCN3 CNGA4

1.17e-0310942250
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3G APOBEC3F

1.71e-0312942406
GeneFamilyATP binding cassette subfamily C

ABCC9 ABCC12

2.01e-0313942807
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA10

2.34e-0314942805
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KIF1A MYO10 KIF1B FERMT3 ADAP2

4.42e-03206945682
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT12 GALNT13

4.78e-0320942433
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

ZRANB3 ZRANB1

5.27e-032194289
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

TMPPE NPR2 POLG NAGLU POR NHLRC3 ZZEF1 MAPK8IP3 KATNBL1 LRP1 POFUT1 PAN3 HTT

2.26e-0645714913M1613
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

TMPPE NPR2 POLG NAGLU POR NHLRC3 ZZEF1 MAPK8IP3 KATNBL1 LRP1 POFUT1 PAN3 HTT

3.08e-0647014913MM1053
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

CACNA1B ADGRL1 CBARP RAB6B C2CD2L CLVS2 TTLL11 RAB6A

3.06e-0719414988aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A MYO10 KIF1B ADRA2A DST FAM151A TMEM163 DYNC1H1

3.18e-0719514987796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B ABCA13 NDST4 MDGA2 FREM2 OTOGL ACSM2B

5.97e-07145149796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB1 ABCC9 MYO1B MDGA2 CLVS2 MED12L LRP6

1.02e-061571497bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B ABCA13 NDST4 MDGA2 FREM2 OTOGL ACSM2B

1.26e-061621497bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

KIF1A APOBEC3G ABCC9 NRROS ADRA2A GPR142 MED12L

1.37e-061641497362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNJL IL34 ABCC9 MYO1B MDGA2 CFAP54 ADAP2

1.95e-061731497d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNJL IL34 ABCC9 MYO1B MDGA2 CFAP54 ADAP2

1.95e-0617314973c852ffe22f4a5b632463086b08c669310684e80
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4V2 NDST4 GALNT12 MDGA2 GALNT13 SYTL5 LRRTM4

2.73e-061821497eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 MDGA2 PKD1L2 GALNT13 FREM2 OTOGL LRP2

2.93e-0618414972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 MDGA2 PKD1L2 GALNT13 FREM2 OTOGL LRP2

2.93e-061841497ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 MDGA2 PKD1L2 GALNT13 FREM2 OTOGL LRP2

2.93e-0618414972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A PKP4 ADGRL1 ADRA2A DST FAM151A TMEM163

3.75e-0619114973387b95a3f2445c672d407922fdce3a91eabaef8
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 GJB5 ADRA2A ASB10 DHRS7C ADAP2

4.16e-061941497fb234d97191c95b7880280c6e4ed5df124ffb0e1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A KIF1B ADRA2A DST FAM151A TMEM163 DYNC1H1

4.30e-0619514973e519cffa6144a62b06124642a14c9ff39b76554
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 HCN3 XRCC2 SPAG5 ANGPT4 DEPDC1B

2.12e-0516714967efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC1A3 GALNT13 FREM2 MMEL1 OTOGL LRP2

2.26e-0516914960cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC1A3 GALNT13 FREM2 MMEL1 OTOGL LRP2

2.26e-0516914966937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL34 ADGRB1 OTOGL CLVS2 LRP1 NEURL1B

2.34e-0517014965570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC35C1 PKP4 AP2A1 TECPR2 MED12L SLC49A3

2.50e-0517214961bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

POR CRYL1 OTOGL LRP2 ACSM2A ACSM2B

2.58e-0517314968888434641ea554a9b62c436e87920378eef29cd
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPR2 SCD5 SPAG5 TVP23C ESPL1 DEPDC1B

2.67e-05174149694575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPR2 SCD5 SPAG5 TVP23C ESPL1 DEPDC1B

2.67e-05174149640c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 TMPRSS9 HCN3 ABCC9 MYO1B ADAP2

2.67e-051741496a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPR2 SCD5 SPAG5 TVP23C ESPL1 DEPDC1B

2.67e-051741496b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 TMPRSS9 HCN3 ABCC9 MYO1B ADAP2

2.67e-0517414967cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CBARP FREM2 GJB5 FAM151A LRP2 CFAP57

2.67e-0517414964da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FBXL13 MYO10 MYO1B SPNS3 MED12L TMEM163

2.94e-0517714963a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FBXL13 MYO10 MYO1B SPNS3 MED12L TMEM163

2.94e-051771496c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

POR CRYL1 FAM151A LRP2 ACSM2A ACSM2B

3.13e-05179149678fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 SPNS3 NRROS SPAG5 LRP2 FERMT3

3.43e-05182149681c394959414173016426961478f670cd822f8b3
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTN3 SPNS3 NRROS SPAG5 LRP2 FERMT3

3.43e-05182149641a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

NPR2 XRCC2 SPAG5 TVP23C ESPL1 DEPDC1B

3.54e-05183149609c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

FBXL13 TBC1D2 IL18RAP KIAA0319 KATNBL1 TECPR2

3.54e-051831496da43827952e6fdee2ce94648c316182f272b321c
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO10 USP43 MDGA2 SCD5 GALNT13 TMEM163

3.54e-0518314968c8ce5a0d5535bef58ac10b7eb726f9c50af2ed8
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DRD5 MYH7B NDST4 XRCC2 LRRIQ1

3.92e-05113149579ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DRD5 MYH7B NDST4 XRCC2 LRRIQ1

3.92e-05113149591d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DRD5 MYH7B NDST4 XRCC2 LRRIQ1

3.92e-05113149534ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PKP4 USP43 MAPK8IP3 CFAP54 TMEM163

3.99e-051871496c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A PKP4 ADGRL1 ADRA2A DST FAM151A

4.11e-051881496a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 GJB5 LRRIQ1 DHRS7C ADAP2

4.11e-051881496d534ed9870405a3c1075962308f72b460aed17bf
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCAPD3 XRCC2 SPAG5 TMEM163 ESPL1 DEPDC1B

4.23e-051891496d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 MYO1B MDGA2 NALF2 ADAP2

4.49e-0519114969c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 MYO1B ADRA2A DHRS7C ADAP2

4.49e-051911496f932980baa032748857cb367a55c37dd975c693e
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 MYO1B MDGA2 NALF2 ADAP2

4.49e-051911496a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

POR MYO1B CRYL1 DST ACSM2A ACSM2B

4.62e-051921496e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D5 MED13L LRP2 PAN3 ACSM2A ACSM2B

4.62e-051921496e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 NCAPD3 ABCC9 MYO1B ADRA2A ADAP2

4.76e-051931496b9e11cd0896c0868aab7faec4ab7ab4d4e4d1b47
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA KIF1A KIF1B DST FAM151A ANAPC5

4.90e-0519414963a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

USP43 FREM2 CFAP54 ADRA2A LRRIQ1 LRP2

4.90e-0519414966b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBC1D2 MYO1B SCD5 GALNT13 KIAA0319 DST

5.04e-051951496a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL34 ABCC9 MYO1B SYDE1 NEURL1B ADAP2

5.33e-051971496452be45f4aac8459dd860493171f5f715368d663
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

APMAP GRAMD1A KIF1B POR IL18RAP PXN

5.64e-05199149650242666def13e5d4149c563ae000d6768f086f7
ToppCellLPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

XRCC2 RAB6B CFAP54 MMEL1 ANAPC5 FERMT3

5.64e-051991496b68648b4559e452656dc9e6a0974233e842f5e0d
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

XRCC2 SCD5 GALNT13 KIAA0319 NEURL1B DEPDC1B

5.64e-0519914961d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SPNS3 KIAA0319 CFAP54 ADRA2A LRRIQ1 CFAP57

5.80e-05200149696701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

MYO10 NEUROD4 XRCC2 SLC1A3 SPAG5 DEPDC1B

5.80e-052001496971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

NCAPD3 CAPN14 FBXL13 XRCC2 ESPL1 DEPDC1B

5.80e-052001496f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC9 MYO1B OTOGL CLVS2 LRP1 LRP6

5.80e-052001496bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell(18)_cycling_gd_T|World / shred on Cell_type and subtype

CCNJL SAMD1 XRCC2 SPAG5 ESPL1 DEPDC1B

6.29e-0520314967d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMPRSS9 HTR5A KIF1A RNF40 DEPDC1B

9.13e-05135149588f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MDGA2 LRRTM4 LRP2 ACSM2A ACSM2B

1.05e-041391495a1945b07f177cde40e7eea03a19236ce76165857
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB1 ABCC9 MDGA2 CLVS2 MED12L

1.80e-0415614956365b69ede98bc866e996bc52736b00401aacf6f
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B TMPRSS9 HECTD3 MIGA2 CFAP57

1.85e-0415714954766f7d545bf2d775390589460677519cb92f4d5
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B GALNT13 LRRTM4 LRP2 ABCC12

2.02e-041601495c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B GALNT13 LRRTM4 LRP2 ABCC12

2.02e-04160149525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS9 RAB6B SLC1A3 NEURL1B ESPL1

2.08e-0416114958ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SCD5 SLC1A3 GJB5 DST

2.08e-041611495da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SCD5 SLC1A3 GJB5 DST

2.08e-041611495d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

TMPPE IL18RAP ADRA2A MED12L FERMT3

2.14e-041621495e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellBronchial-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL34 KIF1A CLCC1 TTLL11 DEPDC1B

2.14e-041621495afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-3|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

CLCC1 APOBEC3F DST PXN DEPDC1B

2.20e-0416314950e8d3c98209fc98b86b841d69051cee9e276d837
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CACNA1B POR RAB6B FREM2 METTL24

2.27e-04164149581c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBXL13 USP43 GALNT12 TTLL11 TMEM163

2.54e-0416814959e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 USP43 CFAP54 LRRIQ1 CFAP57

2.61e-04169149514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCTRL-Myeloid-Neutrophil|CTRL / Disease state, Lineage and Cell class

CCNJL FBXL13 IL18RAP TECPR2 PXN

2.83e-041721495ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF1A SLC35C1 RAPGEF1 CUL9 NRROS

2.83e-0417214953b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid|bone_marrow / Manually curated celltypes from each tissue

PRTN3 SPNS3 SLC1A3 SPAG5 DEPDC1B

2.90e-0417314955645a3b1e805c71d5d65fc8e4edc4e13208063fc
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 SCD5 SPAG5 TECPR2 NEURL1B

2.90e-04173149520a20429aa898097d5ec4880ed64846558b5890f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 GALNT12 NHLRC3 FREM2 GJB5

2.98e-041741495c58328c2f262506a4518f49f148e29874faf9171
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRTN3 SEC24A ABCC9 SPNS3 SLC49A3

2.98e-041741495eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

TBC1D2 MYO1B SCD5 GALNT13 DST

2.98e-041741495548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRTN3 SEC24A ABCC9 SPNS3 SLC49A3

2.98e-04174149532fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

FBXL13 IL18RAP KIAA0319 KATNBL1 TECPR2

3.06e-0417514958020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 XRCC2 NEURL1B ESPL1 DEPDC1B

3.06e-041751495876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 GALNT12 SPNS3 RAB6B TMEM163

3.14e-041761495d4075796c38b775fe721abb47426e662a0d415e3
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 SLC1A3 DST LRP1 ADAP2

3.22e-04177149526bad614560609d318bfc9c235a698bca4e1c22c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST4 EVPL GALNT13 SYTL5 ABCC12

3.22e-0417714951dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST4 EVPL GALNT13 SYTL5 ABCC12

3.22e-041771495426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CCNJL SYTL5 TMEM163 DEPDC1B

3.28e-04981494fca0baf13520c53edb6da2fe3eb152fbd44df5ed
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRYL1 FREM2 LRP2 ACSM2A ACSM2B

3.31e-04178149523a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 SLC1A3 DST LRP1 ADAP2

3.31e-0417814956c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 MYO1B ASB10 CFAP57 ADAP2

3.31e-0417814957467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL34 ABCC9 FREM2 NEURL1B ADAP2

3.31e-0417814956bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MDGA2 CFAP54 LRP2 TMEM163 ACSM2A

3.31e-041781495544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

CCNJL NHLRC3 IL18RAP DST SLC49A3

3.39e-04179149590e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRP2 TMEM163 ACSM2A ACSM2B

3.39e-04179149558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CRYL1 OTOGL LRP2 ACSM2A ACSM2B

3.48e-041801495f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCelldroplet-Kidney-nan-18m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 FAM151A CLVS2 LRP2 ACSM2B

3.48e-041801495cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 GALNT12 SPNS3 RAB6B TMEM163

3.48e-04180149564f01494a4052186773720e10b4e7c724ff94547
DrugSulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

TRPM4 COPA SLC35C1 POLG C2CD2L AP5Z1 PXN POFUT1 PLEC

6.14e-0619814894979_DN
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; PC3; HT_HG-U133A

SEC24A SENP3 ADGRL1 MYO1B PSMD13 CLCC1 AP5Z1 POFUT1 BRWD1

6.66e-0620014896284_DN
Drug5-fluorocytidine

POLG APOBEC3G APOBEC3F PLEC

1.95e-05251484CID000016861
DrugCB1954

NPR2 POR APOBEC3G APOBEC3F

3.59e-05291484CID000089105
Drugmonatepil

SAMD1 LRP1 LRP2 LRP6

3.59e-05291484CID000060810
DrugGSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A

SEC24A TBC1D5 POLG CUL9 CLCC1 NLE1 PLEC SLC25A28

3.95e-0519314887097_UP
DrugDiphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A

POR ADGRL1 TECPR2 PXN IGSF1 PLEC ANAPC5 BRWD1

4.10e-0519414887406_DN
DrugICI 182,780; Up 200; 1uM; HL60; HT_HG-U133A

POLG ADGRL1 MYO1B BTN3A1 SYDE1 CRYL1 LRP6 HTT

4.10e-0519414881146_UP
DrugProbenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A

ABCC9 EVPL SCD5 MAPK8IP3 GDPD5 PXN POFUT1 ADAP2

4.10e-0519414882825_UP
Drug5-bromo-2-pyrimidinone

APOBEC3G APOBEC3F

4.20e-0521482CID000101494
DrugHesperetin [520-33-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

COPA TBC1D5 ADGRL1 MYO1B MAPK8IP3 C2CD2L PXN LRP6

4.40e-0519614881531_DN
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A

ENTPD7 KIF1A SENP3 ADGRL1 ABCC9 BTN3A1 GDPD5 CRYL1

4.57e-0519714882129_UP
DrugSB 202190; Down 200; 1uM; MCF7; HT_HG-U133A

TRPM4 ASXL1 SENP3 PXN POFUT1 SLC25A28 ADAP2 BRWD1

4.57e-0519714886909_DN
DrugMethyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A

ENTPD7 NPR2 TBC1D5 EVPL C2CD2L AP5Z1 LRP2 PXN

4.57e-0519714884986_DN
DrugDelsoline [509-18-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A

SLC35C1 SEC24A POLG EVPL MYO1B GDPD5 LRP6 POFUT1

4.90e-0519914887212_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A

KIF1A TBC1D2 SYDE1 MAPK8IP3 CRYL1 LRP6 POFUT1 PLEC

4.90e-0519914882402_DN
DrugMesalamine [89-57-6]; Up 200; 26.2uM; MCF7; HT_HG-U133A

TBC1D5 TBC1D2 CUL9 ZZEF1 RAB6B GDPD5 LRP6 POFUT1

5.08e-0520014883584_UP
DiseaseX-21319 measurement

ACSM2A ACSM2B

2.43e-0521462EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

7.27e-0531462EFO_0021242
DiseaseLeukocyte adhesion deficiency

SLC35C1 FERMT3

7.27e-0531462cv:C0272187
DiseaseDNA dC->dU-editing enzyme APOBEC-3G measurement

APOBEC3G APOBEC3F

7.27e-0531462EFO_0802473
Diseasetriclosan measurement, 8-hydroxydeoxyguanosine measurement

USP43 DHRS7C

1.45e-0441462EFO_0801078, EFO_0801081
Diseasesynucleinopathy (biomarker_via_orthology)

KIF1A KIF1B

1.45e-0441462DOID:0050890 (biomarker_via_orthology)
DiseaseParkinson disease

CACNA1B TMPRSS9 TBC1D5 NAGLU MDGA2 HEATR6 MED12L TMEM163

2.07e-043211468MONDO_0005180
Diseasedodecadienoate (12:2) measurement

ECI1 ACOT2

2.41e-0451462EFO_0800572
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

2.41e-0451462EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

3.60e-0461462EFO_0800106
Diseaseepidermolysis bullosa simplex (is_implicated_in)

DST PLEC

5.02e-0471462DOID:4644 (is_implicated_in)
Diseaseoctadecanedioylcarnitine (C18-DC) measurement

CYP4V2 ACOT2

5.02e-0471462EFO_0800371
Diseasehereditary spastic paraplegia (is_implicated_in)

KIF1A AP5Z1

5.02e-0471462DOID:2476 (is_implicated_in)
Diseaseage at first sexual intercourse measurement

TBC1D5 MDGA2 TTLL11 POFUT1 FBXO33 IGSF1 DEPDC1B BRWD1

6.67e-043831468EFO_0009749
Diseaseage at initiation of corrective lens use

TBC1D5 BRWD1

6.68e-0481462EFO_0021781
DiseaseImmature Reticulocyte Fraction Measurement

S1PR2 FERMT3

1.07e-03101462EFO_0009253
Diseaseresponse to simvastatin, myopathy

ABCA13 SPNS3 CLVS2

1.10e-03411463EFO_0004145, GO_1903491
Diseasecortical thickness

IL34 NPR2 FBXL13 TBC1D5 CUL9 ABCC9 GALNT12 SPNS3 MAPK8IP3 LRRIQ1 ANGPT4 LRP1 CFAP57 PLEC

1.29e-03111314614EFO_0004840
Diseaseurinary uromodulin measurement

LRRTM4 ACSM2A DYNC1H1 ACSM2B

1.34e-03961464EFO_0005663
Diseasenervous system disease (implicated_via_orthology)

KIF1A KIF1B

1.55e-03121462DOID:863 (implicated_via_orthology)
DiseaseIntellectual Disability

CACNA1B NAGLU MED13L MAPK8IP3 MED12L LRP2 DYNC1H1 HTT

1.78e-034471468C3714756
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH7B SCD5

1.83e-03131462DOID:397 (implicated_via_orthology)
Diseaseglycochenodeoxycholate glucuronide (1) measurement

ENTPD7 SLC25A28

1.83e-03131462EFO_0800474
DiseaseProteinuria

CRYL1 LRP2

2.45e-03151462HP_0000093
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ASXL1 POLG

2.45e-03151462DOID:0050908 (implicated_via_orthology)
Diseasegout

ABCC9 DST ASB10 LRP2 ACSM2B

2.98e-031961465EFO_0004274
DiseaseCharcot-Marie-Tooth disease type 2

KIF1B DYNC1H1

3.15e-03171462cv:C0270914
Diseasefibroblast growth factor basic measurement

NHLRC3 CLCC1 METTL24

3.15e-03591463EFO_0008130
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

DRD5 ADRA2A

4.36e-03201462DOID:1094 (is_implicated_in)
Diseaseeye colour measurement

GALNT12 MDGA2 LRRTM4 LRP2 ZRANB1

4.67e-032181465EFO_0009764

Protein segments in the cluster

PeptideGeneStartEntry
QVLNTLWQYRDLRSI

PKP4

986

Q99569
QTSYRDLWSLRASLE

CBARP

431

Q8N350
EIAVIRDWLLNYNLT

EPG5

871

Q9HCE0
RYWAQLDETVEALLR

RNF40

96

O75150
ITKILRSWREYDLAV

CFAP54

1211

Q96N23
LWRRQIYAVATLRFL

ABCA10

751

Q8WWZ4
VKLLEELRWRSIQYA

BTN3A1

306

O00481
SVWRYIRSERSVILI

ADGRB1

971

O14514
FYNRPILSRRNTVWL

APOBEC3G

21

Q9HC16
YQGRINELLLSVITW

ADGRL1

851

O94910
RTLYINSRQLVSLQW

ACSM2A

21

Q08AH3
NIRALRLWSLTYEEE

ASB10

101

Q8WXI3
LQLSPYWTRDLQRIS

CCNJL

266

Q8IV13
WYVDTILNLIRIAGD

AP2A1

441

O95782
QSNWRYFTELILRPI

ABCA13

1516

Q86UQ4
AVLRASRLYQWSLKS

ACOT2

26

P49753
YRATRLWNETVELFR

DEPDC1B

11

Q8WUY9
FLSAANRWLEVRTDY

ABCC9

1211

O60706
DSSSKWQRRDYLLLV

APMAP

216

Q9HDC9
NWTARAALLYLDART

NPR2

161

P20594
LSKRLVDWLRYASLQ

AP5Z1

176

O43299
YWSSLRNLVVSLLNS

CACNA1B

591

Q00975
NVLLFYRLWSLERTA

GRAMD1A

626

Q96CP6
RTWAEAARLVLENYS

ASXL1

11

Q8IXJ9
EILSDVASRLWFTYR

ATG4B

41

Q9Y4P1
IVDWFNALRAARLQY

ADAP2

221

Q9NPF8
LWDILIEATYNRTLI

CAPN14

221

A8MX76
YNRSDVFEAWRLLLT

NAGLU

531

P54802
YLEDRTVRLQLWDTA

RAB6A

56

P20340
YLEDRTVRLQLWDTA

RAB6B

56

Q9NRW1
ASILNLCVISVDRYW

DRD5

126

P21918
ISVLLSVAELYWRSS

ANAPC5

581

Q9UJX4
AASALLYRHWIEIVL

IL18RAP

376

O95256
FWRKRSISELVAYLL

KATNBL1

171

Q9H079
EWTQISTRYLREQLA

MED12L

186

Q86YW9
LRFVLEQYNALSWLT

MED13L

2166

Q71F56
VWVSIRLDSTLRLYH

MAPK8IP3

1101

Q9UPT6
LRSIYLQWNRIRSIS

LRRTM4

231

Q86VH4
YLSWVVEARRHILAI

POR

416

P16435
RTAQLVYDREVQWTL

ENTPD7

501

Q9NQZ7
LSSLENTRWLEYVRA

MTMR10

366

Q9NXD2
VVSWHYLINEIDRIR

DST

976

Q03001
YRDSVLTWLLRENLG

KIF1B

306

O60333
KRILWIDARSDAIYS

LRP1

1446

Q07954
RSIRLWNYETNTLEL

CFAP57

411

Q96MR6
INDTLTRYRWLISAP

FREM2

2426

Q5SZK8
AVLVLQVWDYDRISA

FER1L4

1586

A9Z1Z3
ALQLSARWLEVLRTY

FBXO33

171

Q7Z6M2
TYDRLFRWLVSRINQ

MYH7B

476

A7E2Y1
TIRSQYRDLLKAASW

EVPL

206

Q92817
IQYLELDRLVWRNSI

FBXO39

131

Q8N4B4
QRLVEERYSWTSQLS

POLG

226

P54098
VDQYARIWNALVTAL

HEATR6

1036

Q6AI08
YRNVLEALWRIIRTE

SLC25A28

111

Q96A46
FRAIEALLQYWINTL

MRS2

186

Q9HD23
RLYTKLLNEATRWSS

MYO10

1476

Q9HD67
AKRRLYWTDLDTNLI

LRP6

801

O75581
SVLAVLRNRWLSDSF

MIGA2

451

Q7L4E1
VSRQELRDYASWNLS

GDPD5

436

Q8WTR4
QRWRLSLASLLFFTV

NALF2

41

O75949
YWVDASLQRIERSTL

LRP2

2566

P98164
RNTDRQWLIDTLYAF

PSMD13

226

Q9UNM6
IERWLTYFATSQLLI

NDST4

751

Q9H3R1
VALYVDWIRSTLRRV

PRTN3

236

P24158
TRYLRTWFLVDLISS

HCN3

166

Q9P1Z3
SARTIQNYLVWRLVL

MMEL1

391

Q495T6
ESTLLYSIEERRLAW

LRRIQ1

731

Q96JM4
VLTYEWRLGNKLLRT

MDGA2

571

Q7Z553
SRILRYLFDNTWLDA

PKD1L2

2116

Q7Z442
EAWSTLLRTVYSVIN

GALNT13

126

Q8IUC8
RAILENYISALNTLW

PXN

481

P49023
LIWAYIVQLSSALRT

PAN3

616

Q58A45
LRALQIALVVSLYWV

SLC35C1

36

Q96A29
LWLRLYQSNLVLVSA

ECI1

131

P42126
FYNRPILSRRNTVWL

APOBEC3F

21

Q8IUX4
AWYLLRVQVLQLVAA

ESPL1

896

Q14674
IDVLTLRNSSYWLVR

HTT

851

P42858
LRNSSYWLVRTELLE

HTT

856

P42858
SERELRYLWVLVSLS

IL34

86

Q6ZMJ4
LTWNYVLNEAIRLSL

IGSF1

511

Q8N6C5
KVLIYLRSANWDTRI

BTAF1

46

O14981
ASLLTVFAWLLQYAR

C2CD2L

21

O14523
LLSQSERYSLTLWQA

FAM151A

261

Q8WW52
LTAVWVARNRFAVLD

COPA

416

P53621
VDWFLDRLRTTTNVL

SLC1A3

471

P43003
NEAWSTLLRTVYSVL

GALNT12

146

Q8IXK2
TASIWNVTAIALDRY

HTR5A

126

P47898
NVTAIALDRYWSITR

HTR5A

131

P47898
TRRAAYSLRVELQDW

ANGPT4

371

Q9Y264
LSLLQRVASYARKWQ

CYP4V2

31

Q6ZWL3
YIVSTLQRWRLNVLR

FBXL13

211

Q8NEE6
RLSALVWEVRYIEHN

BRWD1

1221

Q9NSI6
VWIAILLTVDRYTAL

GPR142

246

Q7Z601
SFWLNLERALYRIQE

DYNC1H1

276

Q14204
LFYTIRAQAWSRDIA

CUL9

1316

Q8IWT3
VYSRIEQLLTSDWAV

CXorf38

201

Q8TB03
NRLQYAIISEAWRLV

CRYL1

196

Q9Y2S2
WERLENLYDALISVA

DHRS7C

71

A6NNS2
FRVLVYLVTAERVWS

GJB5

31

O95377
YQEWILDTIDSLRSR

SAMD1

31

Q6SPF0
SLLNPVIYTWRSRDL

S1PR2

281

O95136
YRDSVLTWLLRENLG

KIF1A

306

Q12756
TRLRVLNVSYNVLEW

NRROS

226

Q86YC3
VWDLAQQVVLSSYRA

WDR77

151

Q9BQA1
RIYIQLTSAWKRRTL

OTOGL

601

Q3ZCN5
LWVRSLDAQSVYVAT

POFUT1

296

Q9H488
EEAWRFLRYISTTQI

METTL24

126

Q5JXM2
AYLQSLEPSSRRWVL

SYDE1

71

Q6ZW31
LETRTLQLSVWHYDR

SYTL5

486

Q8TDW5
AVYQIAWSADSRLLV

NLE1

416

Q9NVX2
DYTTWTALLSRSRQL

SPAG5

651

Q96R06
ESARIIAFISWLREQ

SEC24A

1031

O95486
LATVTKLEDIYRWLN

PKDREJ

1751

Q9NTG1
LRYTISLNISWLVNS

SCD5

226

Q86SK9
ALAWAINYRTAIRLK

ABCC12

181

Q96J65
AISLDRYWSITQAIE

ADRA2A

141

P08913
RTLYINSRQLVSLQW

ACSM2B

21

Q68CK6
RLDYSRIIQSWEKIS

NCAPD3

731

P42695
YVRWYTQLRRVLIIS

CLCC1

206

Q96S66
SALKIAYRIERLEWQ

CNGA4

521

Q8IV77
WDQSRYTLVDILRAI

CLVS2

126

Q5SYC1
YARRWVFLLAISLLN

SLC49A3

26

Q6UXD7
WSLISVDVRRRTITY

SENP3

466

Q9H4L4
AVDILYIDITRRWNS

TTLL11

681

Q8NHH1
QLAALVRALWTREYT

USP43

146

Q70EL4
DINSFTRITDRALYW

TVP23C

201

Q96ET8
ELIRDTRWDIQSYTT

XKRY

141

O14609
AVSWRTEKILYRLDV

NHLRC3

36

Q5JS37
LTALYLERDETRAWQ

SPNS3

466

Q6ZMD2
SRVYQSLANLIRWSD

RAPGEF1

156

Q13905
NLALRDTVLAYWADR

NEURL1B

136

A8MQ27
YARVTRLRDWILEAT

TMPRSS9

421

Q7Z410
RASWTSILAKQRELY

TBC1D13

56

Q9NVG8
VRLTQLYEQARWDLL

FERMT3

266

Q86UX7
VVWALTEQRALLYRE

TECPR2

946

O15040
DSTLRYLQDLLAWVE

PLEC

656

Q15149
LALNIWVTVTVLRYR

SLC66A3

181

Q8N755
LILDSLSAFYWIDRV

XRCC2

146

O43543
INLRLSETWLRNYQV

TRMT6

421

Q9UJA5
VLYARHVLASLLAEW

ZZEF1

2616

O43149
ISRIEELRAWYSNIK

TBC1D5

106

Q92609
ILDVLSSAIVLWRYS

TMEM163

126

Q8TC26
SAYLDELRLAVAWNR

TRPM4

391

Q8TD43
SLSQRLRLYLADSWN

TRPM4

851

Q8TD43
TRLDSRLYALWNRTA

ZRANB1

426

Q9UGI0
LISNILLRVWDAFLY

TBC1D2

801

Q9BYX2
YRSLILRFVREWSSL

ZRANB3

781

Q5FWF4
ASRSYLAESLELRAW

TMPPE

26

Q6ZT21
LRWEQVVDLTYSHRL

HECTD3

176

Q5T447
SRSTDDQRIVSYLWI

KIAA0319

741

Q5VV43
LYSRLFSWLVNRINE

MYO1B

356

O43795
IETLRLARNYIWALS

NEUROD4

126

Q9HD90
LARNYIWALSEVLET

NEUROD4

131

Q9HD90