Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

SH3PXD2A NCF1C NCF1B

7.85e-0610823GO:0016176
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1C NCF1B KMO

7.24e-0520823GO:0050664
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC22A4 SLC22A5

9.94e-054822GO:0015199
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM33 UBE4B RNF19A BIRC2 HERC6 TOPORS FBXO30 TRIM7

1.44e-04372828GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM33 UBE4B RNF19A BIRC2 HERC6 TOPORS FBXO30 TRIM7

2.29e-04398828GO:0061659
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A4 SLC22A5

2.47e-046822GO:0015226
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

SH3PXD2A NCF1C NCF1B

3.97e-0435823GO:0043325
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRIM33 UBE4B RNF19A BIRC2 HERC6 TOPORS FBXO30 TRIM7

7.19e-04473828GO:0004842
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1C NCF1B

1.07e-0312822GO:0016175
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRIM33 UBE4B RNF19A BIRC2 HERC6 TOPORS FBXO30 TRIM7

1.20e-03512828GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRIM33 UBE4B RNF19A BIRC2 HERC6 TOPORS FBXO30 TRIM7

1.53e-03532828GO:0016755
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A4 SLC22A5

1.69e-0315822GO:0015651
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KANSL1 UBE4B PLEKHM2 TMEM94 INTS1 AKNA C15orf39 ADGRL1 LRRK1 CABIN1 IQGAP3 ABTB2 MED13 RASAL1 TRIM7 NOD2

6.79e-091105831635748872
Pubmed

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383315685536
Pubmed

Functional variants of OCTN cation transporter genes are associated with Crohn disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383315107849
Pubmed

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383316771961
Pubmed

Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis.

SLC22A4 SLC22A5 NOD2

1.31e-08383316255050
Pubmed

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.

SLC22A4 SLC22A5 NOD2

1.31e-08383316441470
Pubmed

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383316344054
Pubmed

OCTN and CARD15 gene polymorphism in Chinese patients with inflammatory bowel disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383318756601
Pubmed

Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn's disease.

SLC22A4 SLC22A5 NOD2

1.31e-08383317006998
Pubmed

Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases.

SLC22A4 SLC22A5 NOD2

5.23e-08483317451203
Pubmed

Risk factors for perianal Crohn's disease: the role of genotype, phenotype, and ethnicity.

SLC22A4 SLC22A5 NOD2

5.23e-08483317509030
Pubmed

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

SLC22A4 SLC22A5 NOD2

5.23e-08483317786191
Pubmed

Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease.

SLC22A4 SLC22A5 NOD2

5.23e-08483316437728
Pubmed

Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD.

SLC22A4 SLC22A5 NOD2

5.23e-08483316344053
Pubmed

Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study.

SLC22A4 SLC22A5 NOD2

5.23e-08483316670523
Pubmed

Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.

SLC22A4 SLC22A5 NOD2

1.31e-07583317476680
Pubmed

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

SLC22A4 SLC22A5 NOD2

1.31e-07583318162085
Pubmed

A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways.

NCF1C NCF1B NOD2

1.31e-07583323322906
Pubmed

Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.

SLC22A4 SLC22A5 NOD2

1.31e-07583318698678
Pubmed

Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients.

SLC22A4 SLC22A5 NOD2

2.61e-07683318715515
Pubmed

Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk.

SLC22A4 SLC22A5 NOD2

2.61e-07683318433468
Pubmed

Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis.

SLC22A4 SLC22A5 NOD2

4.56e-07783317100974
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ALMS1 PLEKHM2 PCDH11X AKNA C15orf39 FBXO30 DNAH11

1.49e-0623383737704626
Pubmed

Association of genetic profiles to Crohn's disease by linear combinations of single nucleotide polymorphisms.

SLC22A4 SLC22A5 NOD2

2.84e-061283318804983
Pubmed

Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.

SLC22A4 SLC22A5

5.63e-06283221695374
Pubmed

Molecular and functional characterization of organic cation/carnitine transporter family in mice.

SLC22A4 SLC22A5

5.63e-06283211010964
Pubmed

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.

SLC22A4 SLC22A5

5.63e-06283216469794
Pubmed

Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.

SLC22A4 SLC22A5

5.63e-06283221910182
Pubmed

Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.

SLC22A4 SLC22A5

5.63e-06283218274826
Pubmed

Expression patterns of the organic cation/carnitine transporter family in adult murine brain.

SLC22A4 SLC22A5

5.63e-06283217576045
Pubmed

Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.

SLC22A4 SLC22A5

5.63e-06283219814996
Pubmed

Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).

SLC22A4 SLC22A5

5.63e-06283219141711
Pubmed

Contribution of the IBD5 locus to Crohn's disease in the Swedish population.

SLC22A4 SLC22A5

5.63e-06283217340776
Pubmed

Prevalence of SLC22A4 1672T and SLC22A5 -207C combination defined TC haplotype in Hungarian ulcerative colitis patients.

SLC22A4 SLC22A5

5.63e-06283217387389
Pubmed

Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.

SLC22A4 SLC22A5

5.63e-06283232964310
Pubmed

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

SLC22A4 SLC22A5

5.63e-06283221606177
Pubmed

Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.

SLC22A4 SLC22A5

5.63e-06283216835882
Pubmed

Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.

SLC22A4 SLC22A5

5.63e-06283220020740
Pubmed

[Possible role of selected IGR and SLC22A4/SLC22A5 loci in development of inflammatory bowel diseases].

SLC22A4 SLC22A5

5.63e-06283219581171
Pubmed

Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort.

SLC22A4 SLC22A5

5.63e-06283216519742
Pubmed

Functional pseudogenes inhibit the superoxide production.

NCF1C NCF1B

5.63e-06283226086043
Pubmed

Functional activity of L-carnitine transporters in human airway epithelial cells.

SLC22A4 SLC22A5

5.63e-06283226607009
Pubmed

OCTNs: will the real IBD5 gene please stand up?

SLC22A4 SLC22A5

5.63e-06283216773684
Pubmed

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.

SLC22A4 SLC22A5

5.63e-06283216333318
Pubmed

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.

SLC22A4 SLC22A5

5.63e-06283221793125
Pubmed

Organic cation/carnitine transporter family expression patterns in adult murine heart.

SLC22A4 SLC22A5

5.63e-06283219233567
Pubmed

Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium.

SLC22A4 SLC22A5

5.63e-06283218641280
Pubmed

SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.

SLC22A4 SLC22A5

5.63e-06283219659785
Pubmed

Characterization of organic cation/carnitine transporter family in human sperm.

SLC22A4 SLC22A5

5.63e-06283212788076
Pubmed

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.

SLC22A4 SLC22A5

5.63e-06283221706137
Pubmed

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.

SLC22A4 SLC22A5

5.63e-06283216361305
Pubmed

Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.

SLC22A4 SLC22A5

5.63e-06283216796743
Pubmed

Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.

SLC22A4 SLC22A5

5.63e-06283222325173
Pubmed

Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy.

SLC22A4 SLC22A5

5.63e-06283223127916
Pubmed

LPS-induced inflammation delays the transportation of ASP+ due to down-regulation of OCTN1/2 in alveolar epithelial cells.

SLC22A4 SLC22A5

5.63e-06283231591905
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1C NCF1B

1.69e-05383218036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1C NCF1B

1.69e-05383210678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1C NCF1B

1.69e-05383227044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1C NCF1B

1.69e-05383217167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1C NCF1B

1.69e-05383224358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1C NCF1B

1.69e-05383210891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1C NCF1B

1.69e-05383225474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1C NCF1B

1.69e-05383218787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1C NCF1B

1.69e-05383226209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1C NCF1B

1.69e-05383224873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1C NCF1B

1.69e-05383222184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1C NCF1B

1.69e-05383211018074
Pubmed

IRF7 regulates TLR2-mediated activation of splenic CD11c(hi) dendritic cells.

IRF7 ITGAX

1.69e-05383222815909
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1C NCF1B

1.69e-05383233545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1C NCF1B

1.69e-05383220142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1C NCF1B

1.69e-0538329116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1C NCF1B

1.69e-05383220686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1C NCF1B

1.69e-05383221570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1C NCF1B

1.69e-05383225565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1C NCF1B

1.69e-05383239357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1C NCF1B

1.69e-05383212958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1C NCF1B

1.69e-05383211435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1C NCF1B

1.69e-05383231118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1C NCF1B

1.69e-05383223482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1C NCF1B

1.69e-05383216041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1C NCF1B

1.69e-05383210085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1C NCF1B

1.69e-05383210987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1C NCF1B

1.69e-05383221435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1C NCF1B

1.69e-05383218703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1C NCF1B

1.69e-05383229228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1C NCF1B

1.69e-05383217307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1C NCF1B

1.69e-05383222155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1C NCF1B

1.69e-05383227829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1C NCF1B

1.69e-05383224576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1C NCF1B

1.69e-05383222376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1C NCF1B

1.69e-05383223918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1C NCF1B

1.69e-05383228274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1C NCF1B

1.69e-05383226645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1C NCF1B

1.69e-05383212364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1C NCF1B

1.69e-05383224549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1C NCF1B

1.69e-05383234557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1C NCF1B

1.69e-05383228467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1C NCF1B

1.69e-05383210670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1C NCF1B

1.69e-05383220881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1C NCF1B

1.69e-05383226528554
GeneFamilyRing finger proteins

TRIM33 RNF19A BIRC2 TOPORS TRIM7

6.46e-0427546558
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4B PLEKHG4 PLEKHM2 RASAL1

1.84e-03206464682
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

BIRC2 NOD2

2.63e-0330462959
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

TRIM33 KANSL1 UBE4B TMEM94 VPS13C MED13

2.35e-05180836M8239
CoexpressionGSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP

ALMS1 MYO1C SMARCC1 EFCC1 HEATR5B CABIN1

3.09e-05189836M9978
CoexpressionGSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP

STON1 CHAF1A IRF7 HERC6 TMEM255A NOD2

3.90e-05197836M3307
CoexpressionCERVERA_SDHB_TARGETS_1_UP

PLEKHG4B CAND2 PLEKHG4 HRG NOD2

4.04e-05120835M15549
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

RNF19A TTC16 CLIC3 AKNA SMARCC1 ITGAX

1.46e-06189836fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

RNF19A TTC16 CLIC3 AKNA SMARCC1 ITGAX

1.46e-06189836b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG4B TTC16 TNFRSF8 CHAF1A OTOG

1.82e-06108835d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 PLEKHM2 SNX25 LRRK1 ITGAX

1.13e-05157835ec433d2fe827abdb647be4176c231b7052482b6f
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALMS1 BIRC2 IQGAP3 KMO TRIM7

1.57e-051688350e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 STON1 PCDH11X TMEM255A EPG5

1.86e-05174835268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 STON1 PCDH11X TMEM255A EPG5

1.86e-051748354cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN4 SH3PXD2A IRF7 ITGAX KMO

1.96e-0517683574f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN4 SH3PXD2A IRF7 ITGAX KMO

1.96e-0517683531b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 TTC16 CCDC24 DNAH11

2.76e-051898351c28ad1263891d963e483b6847d8e89cc1b2d07e
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 TTC16 CCDC24 DNAH11

2.76e-0518983500b20c2ed7876486c8e42e3a5b13023f44987a34
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPN4 TTC16 CLIC3 IRF7 HERC6

2.83e-05190835b9182c84e44aa31684b5388cf3ef4fd1b9e51de4
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN4 TTC16 CLIC3 IRF7 HERC6

2.83e-0519083588c092a5e78ccaddf406f8fff74376bb761b9790
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPN4 TTC16 CLIC3 IRF7 HERC6

2.83e-051908354b42a16902d7d1494f953cc88af1e761e76bdf2c
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 TTC16 CCDC24 DNAH11

2.83e-0519083573ac7be02742ee6cb003600631f6a03eecbf2083
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN4 TTC16 CLIC3 IRF7 HERC6

2.83e-051908359501f0995f3d52be90c02b1aa0c7d184bd788c16
ToppCell(210)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

RNF19A TTC16 CLIC3 AKNA HERC6

2.98e-0519283508dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell(21)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

RNF19A TTC16 CLIC3 AKNA HERC6

2.98e-05192835b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCellCD8+_Memory_T_cell-CV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ILK RNF19A CLIC3 AKNA IRF7

3.13e-0519483535a347c3824757b9de8b7f49db46e73e7fb63a4f
ToppCellCV-Severe-6|CV / Virus stimulation, Condition and Cluster

RNF19A CLIC3 BIRC2 IRF7 SREK1IP1

3.21e-0519583569095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN4 RNF19A CLIC3 AKNA GDE1

3.37e-051978351ca06d6d288cb58a6e8062ebc01831e58ee5be4b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG4B DRC7 CCDC24 IQGAP3 DNAH11

3.37e-05197835861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

KANSL1 RNF19A VPS13C IRF7 HERC6

3.45e-0519883544417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KANSL1 RNF19A VPS13C IRF7 HERC6

3.45e-0519883528ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHAF1A CLIC3 IRF7 NCF1B SSUH2

3.53e-051998357271dbeca9aa838b88ad44d00059263a29c0316b
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

PTPN4 TTC16 CLIC3 IRF7 HERC6

3.62e-05200835b7f80b2db07119069fbf3d245cf1ad79e8648bab
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD8+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

PTPN4 TTC16 CLIC3 IRF7 HERC6

3.62e-052008357751affe353a5208ffad7a58308c588050e77243
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHM2 ITGAX NCF1C NCF1B NOD2

3.62e-05200835851c57187db8bc91a393655bca5f13e787a723d4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG4B TNFRSF8 CLIC3 OTOG

5.36e-05110834c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA LRRK1 ITGAX IQGAP3

1.69e-0414883412fa2c4922f03803006c606b1b16e79441e3bb13
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 TTC16 CCDC24 DNAH11

1.97e-041548344e3bc24043144143842627cacf6f90dda2228910
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

PTPN4 PLEKHG4 CLIC3 CABIN1

1.97e-04154834187b9d4eb0e98c506034735601ead480ff00bd57
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 TTC16 CCDC24 DNAH11

1.97e-041548347556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC16 RFX8 ITGAX OTOG

2.12e-041578347fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC16 RFX8 ITGAX OTOG

2.12e-04157834c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC16 RFX8 ITGAX OTOG

2.12e-041578346b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

CYP2F1 CLIC3 ZNF76 IRF7

2.22e-0415983497c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

CYP2F1 CLIC3 ZNF76 IRF7

2.22e-04159834fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPN4 TTC16 CLIC3 SSUH2

2.27e-04160834ab633295cb4de88fdbc076295e1352769f47cc00
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 PLEKHM2 SNX25 ITGAX

2.44e-041638348dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 PLEKHM2 SNX25 ITGAX

2.44e-04163834fd243ca223079033be480a24817a399f281fa4d4
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE4B CLIC3 RFX8 SREK1IP1

2.50e-04164834d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

CLIC3 IRF7 ABTB2 KMO

2.50e-0416483406db4cc064f0765c481ce880207823872c27bfa9
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

PTPN4 TTC16 CLIC3 AKNA

2.50e-0416483460fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2A AKNA KMO RASAL1

2.56e-0416583422293c6b55f44636440cd737efb786ff5de3373d
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG8 ABHD17B CCDC15 FBXO30

2.68e-04167834a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C LRRK1 MED13 DNAH11

2.74e-04168834d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellImmune_cells-Dendritic_cells|World / Lineage and Cell class

ABHD17B IRF7 ITGAX KMO

2.87e-04170834094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FSIP2 SACS SNX25 SLC22A5

2.93e-04171834bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

SHANK1 CHAF1A CLIC3 IRF7

2.93e-0417183472c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

PTPN4 TTC16 CLIC3 AKNA

2.93e-041718346be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

CHAF1A C15orf39 ITGAX RASAL1

3.00e-04172834200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALMS1 ITGAX IQGAP3 KMO

3.00e-04172834b043d4f81dced7fb3326043f68474123be47cc5d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA LRRK1 ITGAX NOD2

3.00e-04172834f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A ITGAX IQGAP3 KMO

3.06e-041738342eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG4B AKNA LRRK1 ITGAX

3.06e-0417383473f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALMS1 ITGAX IQGAP3 KMO

3.06e-041738346c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHAF1A CLIC3 IRF7 KMO

3.13e-041748344120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAND2 SH3PXD2A TMEM94 VPS13C

3.13e-04174834f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLIC3 AKNA EFCC1 ITGAX

3.20e-041758348fb8c4b9e2d9b7d737f59cd9bd3dc2bca5a8dfc4
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

PLEKHG4B CLIC3 IRF7 LRRK1

3.20e-0417583429fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKNA LRRK1 ITGAX NOD2

3.27e-04176834926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPN4 TTC16 CLIC3 AKNA

3.56e-041808340a98d21fec67a890e75ebf0e2d23adddd77da214
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHAF1A CLIC3 IRF7 KMO

3.56e-04180834144818e69613296cde43f29cb8c20899c670b319
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPN4 TTC16 CLIC3 AKNA

3.56e-041808341c8398342d3fa4d5ca9a8a63626cc497c5291446
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPN4 TTC16 CLIC3 AKNA

3.56e-04180834ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHAF1A CLIC3 ADGRL1 IRF7

3.71e-0418283402c0824373a0ecebc922d4ca848ace9d570722c4
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN4 CLIC3 AKNA ITGAX

3.71e-04182834feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-mature_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PTPN4 TTC16 CLIC3 AKNA

3.79e-041838348746e6ecc6bf9e194cc9cdf9b07da63f0fcf8b5f
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHM2 INTS1 ITGAX IQGAP3

3.79e-0418383442dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG4B PCDH11X ABTB2 RASAL1

3.95e-04185834d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

PTPN4 CLIC3 IRF7 HERC6

4.03e-04186834ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

PTPN4 TTC16 CLIC3 IRF7

4.11e-041878344c4c4406e16a15dedcd50bbcc2059d722a2e3d2c
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|tumor_Lung / Location, Cell class and cell subclass

PTPN4 TTC16 CLIC3 AKNA

4.11e-04187834530839fb53bb285b22919fde6aa16ce1399615ef
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 CCDC24 DNAH11

4.11e-041878341bba994aaaa9825b54aaeaff3829850267bc4602
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 CCDC24 DNAH11

4.11e-04187834d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

KANSL1 VPS13C MED13 EPG5

4.19e-04188834ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD8+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

PTPN4 TTC16 IRF7 HERC6

4.19e-041888341aecae0d94905bfbd414adf1450035e5b863abe7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKNA C15orf39 ITGAX NOD2

4.28e-04189834a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPN4 TTC16 IRF7 HERC6

4.28e-04189834eb5b107dbc50e538dc27ba2867b196a23a8054bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN4 TTC16 IRF7 HERC6

4.28e-04189834c6760ea8ecca6abdd9eb067f3b3f4eea9420b852
ToppCellCOVID-19_Moderate-NK_activated|COVID-19_Moderate / disease group, cell group and cell class

PTPN4 CLIC3 IRF7 HERC6

4.28e-041898348f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN4 CLIC3 AKNA ITGAX

4.28e-041898345a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPN4 TTC16 IRF7 HERC6

4.28e-04189834af5f92dc3b3bc6acacd633981b8ef7f0c593c92e
ToppCellPND10-Epithelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SNX25 CLIC3 GDE1

4.28e-0418983489349e226a5512833a94b1bf68056a6985fe4afd
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN4 TTC16 IRF7 HERC6

4.28e-0418983404bdcf05b8c72c13e7d35d1c7444f50374d41203
ToppCellmetastatic_Brain-T/NK_cells-NK|metastatic_Brain / Location, Cell class and cell subclass

PTPN4 TTC16 CLIC3 AKNA

4.36e-0419083450e937ba0600e1ac6215f056bb545dc1e8b28a76
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS PLEKHM2 SH3PXD2A ITGAX

4.36e-04190834ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellPND14-Epithelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SNX25 CLIC3 GDE1

4.36e-04190834f1eeef8f201bf7b96c020c8ab53dd7e05b3060ea
ToppCellPND07-Epithelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP2F1 SNX25 CLIC3 GDE1

4.36e-04190834e3a2c8b637f60c963520dffe99c526809d818cab
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

PTPN4 CLIC3 AKNA ITGAX

4.36e-041908341584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 TTC16 CCDC24 DNAH11

4.45e-04191834649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 TTC16 CCDC24 DNAH11

4.45e-041918349621e22e14ea069f22713947c9faa2d882abe5fe
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHANK1 CHAF1A CCDC15 IQGAP3

4.45e-0419183450854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 CCDC24 DNAH11

4.45e-041918346a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPN4 TTC16 CLIC3 AKNA

4.54e-04192834a0bd4a0d00246af4f6645e66a0dedfe36882cc60
ToppCellfacs-Lung-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 CYP2F1 CLIC3 CCDC24

4.54e-04192834ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK|lymph-node_spleen / Manually curated celltypes from each tissue

PTPN4 CLIC3 AKNA ITGAX

4.63e-04193834e325cf49e159c6be205ed93adaa09efdd0c122b4
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPN4 TTC16 CLIC3 AKNA

4.63e-04193834d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

STON1 MYO1C GPR156 IQGAP3

4.63e-041938343091090abcf18b48eac7e6c85653c18aa54fcb9b
DrugCarbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A

TRIM33 SLC22A4 C15orf39 ADGRL1 LRRK1 CABIN1 CDK10 KMO

6.92e-072008383991_DN
DrugHippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; HL60; HT_HG-U133A

CAND2 CRCP SH3PXD2A SLC22A5 ADGRL1 HERC6 KMO

7.27e-061958372187_DN
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1C NCF1B

7.22e-055802DOID:3265 (implicated_via_orthology)
DiseaseCoxsackievirus Infections

SLC22A4 SLC22A5

1.08e-046802C0010246
DiseaseMyocarditis

SLC22A4 SLC22A5

1.08e-046802C0027059
DiseaseCarditis

SLC22A4 SLC22A5

1.08e-046802C0869523
Diseaseacetylcarnitine measurement

SLC22A4 SLC22A5

2.01e-048802EFO_0021038
Diseasebutyrylcarnitine measurement

SLC22A4 SLC22A5

2.01e-048802EFO_0020010
DiseaseIntellectual Disability

PIGB POLR3B KANSL1 SACS TMEM94 CDK10 MED13

2.14e-04447807C3714756
DiseaseN-acetylkynurenine (2) measurement

ALMS1 KMO

2.58e-049802EFO_0800083
Diseasenervonoylcarnitine (C24:1) measurement

SLC22A4 SLC22A5

2.58e-049802EFO_0800549
DiseaseCrohn Disease

SLC22A4 SLC22A5 NOD2

3.43e-0450803C0010346
Diseaselignoceroylcarnitine (C24) measurement

SLC22A4 SLC22A5

3.93e-0411802EFO_0800541
Diseasetryptophan betaine measurement

SLC22A4 SLC22A5

4.71e-0412802EFO_0021017
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1C NCF1B

4.71e-0412802DOID:7148 (implicated_via_orthology)
Diseasehexanoylcarnitine measurement

SLC22A4 SLC22A5

4.71e-0412802EFO_0021040
Diseaseurinary metabolite measurement

GLYATL3 ALMS1 FAM209B CABIN1 KMO

5.49e-04245805EFO_0005116
Diseasehomostachydrine measurement

SLC22A4 SLC22A5

5.55e-0413802EFO_0021164
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC22A4 SLC22A5

5.55e-0413802EFO_0800547
Diseaseximenoylcarnitine (C26:1) measurement

SLC22A5 CCDC24

5.55e-0413802EFO_0800543
Diseasecerotoylcarnitine (C26) measurement

SLC22A4 SLC22A5

5.55e-0413802EFO_0800542
Diseaseorotic acid measurement

ABTB2 DNAH11

6.47e-0414802EFO_0010516
DiseaseParoxysmal atrial fibrillation

CAND2 MYO1C UBE4B SH3PXD2A

8.70e-04156804C0235480
Diseasefamilial atrial fibrillation

CAND2 MYO1C UBE4B SH3PXD2A

8.70e-04156804C3468561
DiseasePersistent atrial fibrillation

CAND2 MYO1C UBE4B SH3PXD2A

8.70e-04156804C2585653
DiseaseAtrial Fibrillation

CAND2 MYO1C UBE4B SH3PXD2A

9.56e-04160804C0004238
DiseaseMuscle hypotonia

KANSL1 INTS1

9.61e-0417802C0026827
Diseaseoleoylcarnitine measurement

SLC22A4 SLC22A5

1.20e-0319802EFO_0021043
Diseasestearoylcarnitine measurement

SLC22A4 SLC22A5

1.93e-0324802EFO_0021045

Protein segments in the cluster

PeptideGeneStartEntry
RHPPTRQFFTSCIEI

EPG5

1686

Q9HCE0
FPERFQRELSLLCPG

ACTL7B

351

Q9Y614
VCAHFRQAPIPAELR

CLIC3

186

O95833
NLHVSPELFCEPREV

ADGRL1

471

O94910
RCNFPAPLARFRDIS

ALMS1

2276

Q8TCU4
GDHRCLVPFRDLNPS

CD300LD-AS1

61

Q96MU5
PLRRHIQCLQETEFP

DNAH11

341

Q96DT5
PRRRTAFHPDLCSQL

CHAF1A

481

Q13111
RRLFQPFGHIEECTV

CELF6

151

Q96J87
EPPELTFRQFHARLC

EFCC1

136

Q9HA90
PLHPFLLQCVSRVRD

RASAL1

526

O95294
LDPRSPRDFIQCFLT

CYP2F1

256

P24903
QFIPAEIPRSAFECR

ITGAX

626

P20702
CVEHHTFFRLDRPLP

PTPN4

301

P29074
REPFRRDNHIESFFC

OR10AD1

166

Q8NGE0
DQPFRVEILCEHPRF

LGALSL

121

Q3ZCW2
VDFSVRNCPRHHFPR

HRG

196

P04196
PPESDRNFFLRLCSE

INTS1

631

Q8N201
TAIERDFISCPRHPD

LRRK1

1196

Q38SD2
LRNAEERLCFPPVHT

FSIP2

4026

Q5CZC0
VPCGEHFRIRQNLPE

FAM209B

36

Q5JX69
RHRPQCFEDTKPAFV

CES5A

436

Q6NT32
IVFRCPETFSERDHP

HERC6

966

Q8IVU3
ERRTFPLAHSPQAEC

KANSL1

1036

Q7Z3B3
LPRNCDTPIFDFRVF

IRF7

396

Q92985
RPLCAPRLLDHFICE

OR2I1P

166

Q8NGU4
VTCFTDHEIPFRLRP

PCDH11X

396

Q9BZA7
FRKFIHRACQVPEPE

IQGAP3

1246

Q86VI3
RCPHLLDFFKVRPDD

NCF1B

111

A6NI72
RCPHLLDFFKVRPDD

NCF1C

86

A8MVU1
RDVSVPLCNHPVRFL

PASD1

591

Q8IV76
EFLPCRFHRLILTPA

GLYATL3

266

Q5SZD4
LLRVFSFEPVPSCRA

GDE1

41

Q9NZC3
LPFQLTPFLDRCAER

HEATR5B

476

Q9P2D3
CLPVFSRLRIPDDHA

KMO

341

O15229
PLARHAFEEGLRCNP

CABIN1

141

Q9Y6J0
FFTVPPEHRLGRCRS

CDK10

21

Q15131
NEECPRLRIFSHPNV

ILK

236

Q13418
RRETTRFFCPQPKEH

AKNA

281

Q7Z591
DRVPLFLHPLNECEV

DRC7

111

Q8IY82
CDSFPGQELDRRPLH

GPR156

11

Q8NFN8
ADEHRLLCPFERVPC

FBXO30

46

Q8TB52
PDFHCTLAPVLIRRF

CAND2

371

O75155
FLAGTPEHRCRVPDA

SLC22A4

41

Q9H015
FLIATPEHRCRVPDA

SLC22A5

41

O76082
ICFVFDPRQHPVDRI

SACS

2561

Q9NZJ4
SPRVLHFALEEPRCD

CCDC24

111

Q8N4L8
HRFVPPESFCELWIR

OTOG

2321

Q6ZRI0
DRPHAFQVILSDRPC

PLEKHM2

836

Q8IWE5
VCDRQVFPLFRHQDP

SMG8

71

Q8ND04
PLLFRHFCQEPRKLD

PIGB

241

Q92521
LHSFCLRCLPEPERQ

TRIM33

146

Q9UPN9
TPCRHQSPEIVREFL

CRCP

56

O75575
VNCPHLSREFCTPRI

TMEM255A

166

Q5JRV8
HFFLRELEACTRHPP

PLEKHG4

791

Q58EX7
HEEQPRPFVLHACLR

SNX25

81

Q9H3E2
DPATQDRRSCLPIHF

MED13

2146

Q9UHV7
NCIHVIERRALPEFF

SMARCC1

461

Q92922
PGHLTFECRNFLRVD

SREK1IP1

21

Q8N9Q2
HVRFLENCQPRAPVT

SHANK1

1491

Q9Y566
FEFVSEHRLNCPREL

SSUH2

261

Q9Y2M2
EPRQLKPEHCFSSFR

ABTB2

461

Q8N961
SHGLALFERCQRPVE

ABHD17B

241

Q5VST6
RRHFPNCPFLENSLE

BIRC2

241

Q13490
PICQDRDFLPRDLHV

CCDC15

601

Q0P6D6
QLQRFDRTHRCPFPH

C15orf39

821

Q6ZRI6
VRHCSAPEDPIFRFS

STK19

81

P49842
LGERAQDLPNHPCRF

TRIM7

366

Q9C029
FRFTDRERHCSPTDP

NOD2

386

Q9HC29
CPECTERFNPHDIRL

RNF19A

176

Q9NV58
SLRSCDNIRIHFPVP

STON1

561

Q9Y6Q2
RSFCHPEPHERDALL

TMEM94

456

Q12767
CPLAVGRSFLRHEEQ

PLEKHG4B

876

Q96PX9
RLPPHISQCDEVFRF

SH3PXD2A

106

Q5TCZ1
SPLSEFRRCPFLEQE

RFX8

151

Q6ZV50
DTNHFRRLLCPDPVC

SPATA31D1

116

Q6ZQQ2
IFHPRCRITLPNDET

UBE4B

711

O95155
LRAFPQDRPFEDTCH

TNFRSF8

16

P28908
HFRIRDTLPEFFPVC

VPS13C

2726

Q709C8
FNVTRPVSPHECRLR

POLR3B

91

Q9NW08
QRFRFTCRAPLADPH

SEMA5B

796

Q9P283
ISAEFFRRNPACLHR

TOPORS

281

Q9NS56
HAAELQPEKPCFRYR

TTC16

161

Q8NEE8
VRTHTGERPFQCPFE

ZNF76

246

P36508
LRHAPRCPENAFFLD

MYO1C

796

O00159