Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of synapse	BSN GIT1 PCLO	1.01e-04	42	43	3	GO:0098918
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	BSN PCLO	1.26e-04	8	43	2	GO:0098882
GeneOntologyBiologicalProcess	alternative mRNA splicing, via spliceosome	RBM15 SRSF6 CDK13 SRRM4 SRSF12	6.23e-07	79	43	5	GO:0000380
GeneOntologyBiologicalProcess	RNA splicing	RBM15 PRPF38B SRSF6 PRPF40A CDK13 SRRM4 CCNL1 SRSF12 ZRANB2	7.53e-07	502	43	9	GO:0008380
GeneOntologyBiologicalProcess	synapse assembly	SRGAP2 GJA10 BSN CSMD2 MARK1 SRGAP3 PCLO	3.14e-06	308	43	7	GO:0007416
GeneOntologyBiologicalProcess	regulation of alternative mRNA splicing, via spliceosome	RBM15 SRSF6 SRRM4 SRSF12	6.86e-06	59	43	4	GO:0000381
GeneOntologyBiologicalProcess	presynapse to nucleus signaling pathway	BSN PCLO	1.27e-05	3	43	2	GO:0099526
GeneOntologyBiologicalProcess	mRNA processing	RBM15 PRPF38B SRSF6 PRPF40A CDK13 SRRM4 SRSF12 ZRANB2	1.57e-05	551	43	8	GO:0006397
GeneOntologyBiologicalProcess	presynaptic signal transduction	BSN PCLO	2.54e-05	4	43	2	GO:0098928
GeneOntologyBiologicalProcess	presynaptic active zone assembly	BSN PCLO	4.23e-05	5	43	2	GO:1904071
GeneOntologyBiologicalProcess	maintenance of presynaptic active zone structure	BSN PCLO	6.33e-05	6	43	2	GO:0048790
GeneOntologyBiologicalProcess	regulation of RNA splicing	RBM15 SRSF6 SRRM4 CCNL1 SRSF12	6.85e-05	207	43	5	GO:0043484
GeneOntologyBiologicalProcess	maintenance of synapse structure	BSN CSMD2 PCLO	7.90e-05	40	43	3	GO:0099558
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	RBM15 SRSF6 PRPF40A CDK13 SRRM4 SRSF12	9.29e-05	358	43	6	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	RBM15 SRSF6 PRPF40A CDK13 SRRM4 SRSF12	9.29e-05	358	43	6	GO:0000377
GeneOntologyBiologicalProcess	mRNA metabolic process	RC3H2 RBM15 PRPF38B SRSF6 PRPF40A CDK13 SRRM4 SRSF12 ZRANB2	9.40e-05	917	43	9	GO:0016071
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	RBM15 SRSF6 PRPF40A CDK13 SRRM4 SRSF12	9.88e-05	362	43	6	GO:0000375
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	RBM15 SRSF6 SRRM4 SRSF12	1.49e-04	129	43	4	GO:0048024
GeneOntologyBiologicalProcess	cell junction assembly	SRGAP2 GJA10 BSN CSMD2 MARK1 SRGAP3 PCLO	1.59e-04	569	43	7	GO:0034329
GeneOntologyBiologicalProcess	presynaptic active zone organization	BSN PCLO	1.89e-04	10	43	2	GO:1990709
GeneOntologyBiologicalProcess	regulation of mRNA processing	RBM15 SRSF6 SRRM4 SRSF12	3.24e-04	158	43	4	GO:0050684
GeneOntologyBiologicalProcess	cell junction maintenance	BSN CSMD2 PCLO	3.37e-04	65	43	3	GO:0034331
GeneOntologyBiologicalProcess	synapse organization	SRGAP2 GJA10 BSN CSMD2 MARK1 SRGAP3 PCLO	4.91e-04	685	43	7	GO:0050808
GeneOntologyBiologicalProcess	synaptic vesicle clustering	BSN PCLO	9.55e-04	22	43	2	GO:0097091
GeneOntologyBiologicalProcess	postsynapse assembly	CSMD2 MARK1 SRGAP3	9.61e-04	93	43	3	GO:0099068
GeneOntologyCellularComponent	nuclear speck	RBM15 IL16 SRSF6 PRPF40A CDK13 CCNL1 SRSF12	2.56e-05	431	43	7	GO:0016607
GeneOntologyCellularComponent	inhibitory synapse	BSN GIT1 PCLO	3.50e-05	31	43	3	GO:0060077
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	BSN PCLO	1.15e-04	8	43	2	GO:0048788
GeneOntologyCellularComponent	presynaptic cytoskeleton	BSN PCLO	3.70e-04	14	43	2	GO:0099569
GeneOntologyCellularComponent	nuclear body	RBM15 GARIN3 IL16 SRSF6 PRPF40A CDK13 CCNL1 SRSF12	4.44e-04	903	43	8	GO:0016604
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	BSN PCLO	1.02e-03	23	43	2	GO:0098831
GeneOntologyCellularComponent	glutamatergic synapse	SRGAP2 BSN CSMD2 GIT1 MARK1 SRGAP3 PCLO	1.28e-03	817	43	7	GO:0098978
GeneOntologyCellularComponent	excitatory synapse	BSN GIT1 PCLO	1.39e-03	107	43	3	GO:0060076
GeneOntologyCellularComponent	ribbon synapse	BSN PCLO	1.97e-03	32	43	2	GO:0097470
GeneOntologyCellularComponent	postsynaptic density	SRGAP2 BSN CSMD2 GIT1 PCLO	2.24e-03	451	43	5	GO:0014069
GeneOntologyCellularComponent	cortical cytoskeleton	BSN MLPH PCLO	2.37e-03	129	43	3	GO:0030863
GeneOntologyCellularComponent	asymmetric synapse	SRGAP2 BSN CSMD2 GIT1 PCLO	2.85e-03	477	43	5	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	SRGAP2 BSN CSMD2 GIT1 PCLO	3.58e-03	503	43	5	GO:0099572
GeneOntologyCellularComponent	cell cortex region	BSN PCLO	3.87e-03	45	43	2	GO:0099738
GeneOntologyCellularComponent	neuron to neuron synapse	SRGAP2 BSN CSMD2 GIT1 PCLO	4.23e-03	523	43	5	GO:0098984
GeneOntologyCellularComponent	postsynapse	SRGAP2 BSN CSMD2 GIT1 MARK1 SRGAP3 PCLO	4.41e-03	1018	43	7	GO:0098794
GeneOntologyCellularComponent	GABA-ergic synapse	BSN GIT1 PCLO	4.65e-03	164	43	3	GO:0098982
Domain	Znf_piccolo	BSN PCLO	4.70e-06	2	41	2	IPR008899
Domain	zf-piccolo	BSN PCLO	4.70e-06	2	41	2	PF05715
Domain	FCH	SRGAP2 SRGAP3	1.06e-03	22	41	2	PF00611
Domain	FCH	SRGAP2 SRGAP3	1.06e-03	22	41	2	SM00055
Domain	FCH_dom	SRGAP2 SRGAP3	1.16e-03	23	41	2	IPR001060
Domain	F_BAR	SRGAP2 SRGAP3	1.37e-03	25	41	2	IPR031160
Domain	F_BAR	SRGAP2 SRGAP3	1.37e-03	25	41	2	PS51741
Domain	UBA	HUWE1 MARK1	1.97e-03	30	41	2	SM00165
Domain	UBA	HUWE1 MARK1	2.83e-03	36	41	2	PF00627
Domain	Znf_FYVE_PHD	BSN MLPH PCLO	4.09e-03	147	41	3	IPR011011
Domain	UBA	HUWE1 MARK1	4.20e-03	44	41	2	IPR015940
Domain	UBA	HUWE1 MARK1	4.77e-03	47	41	2	PS50030
Domain	RhoGAP	SRGAP2 SRGAP3	8.18e-03	62	41	2	SM00324
Domain	RhoGAP	SRGAP2 SRGAP3	8.44e-03	63	41	2	PF00620
Domain	RHOGAP	SRGAP2 SRGAP3	8.70e-03	64	41	2	PS50238
Domain	RhoGAP_dom	SRGAP2 SRGAP3	8.70e-03	64	41	2	IPR000198
Domain	-	SRGAP2 SRGAP3	8.70e-03	64	41	2	1.10.555.10
Domain	RRM_1	RBM15 SRSF6 SRSF12	1.06e-02	208	41	3	PF00076
Domain	RRM	RBM15 SRSF6 SRSF12	1.19e-02	217	41	3	SM00360
Domain	RRM_dom	RBM15 SRSF6 SRSF12	1.34e-02	227	41	3	IPR000504
Domain	RRM	RBM15 SRSF6 SRSF12	1.39e-02	230	41	3	PS50102
Pathway	REACTOME_INACTIVATION_OF_CDC42_AND_RAC1	SRGAP2 SRGAP3	1.39e-04	8	32	2	M27349
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	RC3H2 RBM15 PRPF38B SRSF6 SRRM3 PRPF40A CDK13 SRRM4 SRSF12 ZRANB2	1.86e-08	723	44	10	34133714
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRAPPC10 RBM15 PRPF38B HUWE1 SRSF6 GIT1 PRPF40A CDK13 CCNL1 ZRANB2	3.52e-08	774	44	10	15302935
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	SRGAP2 GIT1 MARK1 SRGAP3 RAB11FIP2	7.04e-07	132	44	5	16944949
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	BSN PCLO	1.56e-06	2	44	2	27321892
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	BSN PCLO	1.56e-06	2	44	2	20332206
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	BSN PCLO	1.56e-06	2	44	2	32493491
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	BSN PCLO	1.56e-06	2	44	2	23403927
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	BSN PCLO	1.56e-06	2	44	2	21935939
Pubmed	The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.	SRGAP2 SRGAP3	1.56e-06	2	44	2	23505444
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	BSN PCLO	1.56e-06	2	44	2	26793095
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	BSN PCLO	1.56e-06	2	44	2	25652077
Pubmed	RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.	SRRM3 SRRM4	1.56e-06	2	44	2	34312180
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SDR42E1 RBM15 HUWE1 SRSF6 PRPF40A CDK13 SRSF12 ZRANB2	2.29e-06	695	44	8	23602568
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	RBM15 PRPF38B CHD1 HUWE1 TTLL6 PCLO ZRANB2	2.79e-06	496	44	7	31343991
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TRAPPC10 FLG SRGAP2 SRSF6 POM121C GIT1 TMEM184B RAB11FIP2 SRSF12 ZRANB2	4.61e-06	1321	44	10	27173435
Pubmed	CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing.	CDK13 CCNL1	4.69e-06	3	44	2	17261272
Pubmed	Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.	SRGAP2 SRGAP3	4.69e-06	3	44	2	19137586
Pubmed	The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.	GIT1 PCLO	1.56e-05	5	44	2	12473661
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	CHD1 SRSF6 POM121C PRPF40A CDK13 DCAF5 ZRANB2	1.70e-05	655	44	7	35819319
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	PRPF38B SRGAP2 GIT1 PRPF40A RAB11FIP2	1.75e-05	255	44	5	15324660
Pubmed	SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.	SRGAP2 SRGAP3	2.34e-05	6	44	2	33514561
Pubmed	Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.	BSN PCLO	2.34e-05	6	44	2	14734538
Pubmed	FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.	SRGAP2 SRGAP3	2.34e-05	6	44	2	12736724
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP2 SRGAP3	2.34e-05	6	44	2	11672528
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	BSN PCLO	2.34e-05	6	44	2	19812333
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RC3H2 CHD1 HUWE1 ZNF831 CDK13 ZRANB2	2.66e-05	469	44	6	27634302
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP2 SRGAP3	3.27e-05	7	44	2	21655271
Pubmed	A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.	SRGAP2 SRGAP3 ZRANB2	4.00e-05	52	44	3	15328020
Pubmed	Superresolution imaging of chemical synapses in the brain.	BSN PCLO	5.60e-05	9	44	2	21144999
Pubmed	Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.	RC3H2 PRPF38B SRSF6	6.15e-05	60	44	3	29055695
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TRAPPC10 IL16 SRGAP2 BSN GIT1 MARK1 PRPF40A SRGAP3 PCLO	6.35e-05	1431	44	9	37142655
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RC3H2 RBM15 SRSF6 PRPF40A CDK13 SRSF12 ZRANB2	6.40e-05	807	44	7	22681889
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	CSMD2 XKR4 CCDC85A	7.11e-05	63	44	3	11572484
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	BSN XKR4 GIT1 SRGAP3 PCLO	7.58e-05	347	44	5	17114649
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PRPF38B HUWE1 BSN GIT1 MARK1 SRGAP3 PCLO RAB11FIP2	8.02e-05	1139	44	8	36417873
Pubmed	Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.	SRGAP2 GIT1	8.54e-05	11	44	2	31388001
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBM15 PRPF38B IP6K1 SRSF6 CDK13	9.13e-05	361	44	5	26167880
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	BSN PCLO	1.02e-04	12	44	2	28386022
Pubmed	The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.	PRPF40A CCDC85A PCLO	1.06e-04	72	44	3	33726789
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF6 SRSF12	1.21e-04	13	44	2	20516191
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	CHD1 HUWE1 BSN SRGAP3 PCLO ZRANB2	1.25e-04	621	44	6	22794259
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	RBM15 CHD1 SRGAP2 HUWE1 GIT1 ARHGEF10 SRGAP3	1.41e-04	916	44	7	32203420
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	BSN PCLO	1.41e-04	14	44	2	16452088
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	BSN PCLO	1.41e-04	14	44	2	21228161
Pubmed	Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.	SRGAP2 PRPF40A	1.41e-04	14	44	2	8605874
Pubmed	Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer.	GJA10 PCLO	1.63e-04	15	44	2	31903119
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PRPF38B CHD1 SRGAP2 SRSF6 GIT1 PRPF40A RAB11FIP2 ZRANB2	1.83e-04	1284	44	8	17353931
Pubmed	A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.	IP6K1 BSN	1.86e-04	16	44	2	25082827
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	IL16 SRSF6 PRPF40A PCLO ZRANB2	1.95e-04	425	44	5	24999758
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	TRAPPC10 GIT1 MARK1 SRGAP3 RAB11FIP2	2.06e-04	430	44	5	32581705
Pubmed	Association analysis of 3p21 with Crohn's disease in a New Zealand population.	IP6K1 BSN	2.10e-04	17	44	2	20307617
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FLG PRPF38B GARIN3 IL16 SRGAP2 DCAF5	2.20e-04	689	44	6	36543142
Pubmed	Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.	SRRM3 SRRM4	2.36e-04	18	44	2	33087486
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TRAPPC10 RBM15 SRGAP2 MARK1 RAB11FIP2	2.44e-04	446	44	5	24255178
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLG RBM15 PRPF38B HUWE1 ARHGEF10 MARK1 ZRANB2	2.48e-04	1005	44	7	19615732
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RBM15 PRPF38B SRSF6 PRPF40A SRSF12 ZRANB2	2.64e-04	713	44	6	29802200
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBM15 PRPF38B SRSF12 ZRANB2	2.87e-04	251	44	4	31076518
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM15 PRPF38B SRSF6 PRPF40A SRSF12 ZRANB2	3.02e-04	731	44	6	29298432
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	PRPF38B HUWE1 CSMD2 ZNF831 SRGAP3 PCLO	3.13e-04	736	44	6	29676528
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	PRPF38B PRPF40A CCNL1	3.15e-04	104	44	3	31365120
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CDK13 DCAF5 SRRM4	3.42e-04	107	44	3	11347906
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RBM15 CHD1 HUWE1 SRSF6 BSN PRPF40A PCLO ZRANB2	3.70e-04	1425	44	8	30948266
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	PRPF38B SRGAP2 PRPF40A CCNL1	3.72e-04	269	44	4	29511261
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IP6K1 POM121C MARK1 CDK13 CCDC85A	3.86e-04	493	44	5	15368895
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLG RBM15 PRPF38B SRSF6 MARK1 PRPF40A ZRANB2	3.88e-04	1082	44	7	38697112
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SRGAP2 GIT1 SRGAP3 PCLO	4.39e-04	281	44	4	28706196
Pubmed	The synaptic vesicle cycle.	BSN PCLO	7.11e-04	31	44	2	15217342
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RBM15 SRGAP2 GIT1 ARHGEF10 DENND2B RAB11FIP2	7.16e-04	861	44	6	36931259
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	RBM15 HUWE1 POM121C PRPF40A	8.19e-04	332	44	4	25693804
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	FLG PRPF38B	1.07e-03	38	44	2	23537643
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RBM15 SRSF6 MARK1 PRPF40A	1.12e-03	361	44	4	30344098
Interaction	SRSF11 interactions	RC3H2 PRPF38B SRSF6 PRPF40A SRRM4 SRSF12 ZRANB2	2.65e-07	203	44	7	int:SRSF11
Interaction	YWHAG interactions	TRAPPC10 RC3H2 RBM15 PRPF38B SRGAP2 HUWE1 GIT1 MARK1 PRPF40A DENND2B RAB11FIP2 SRSF12	9.98e-06	1248	44	12	int:YWHAG
Interaction	YWHAE interactions	RC3H2 RBM15 SRGAP2 HUWE1 SRSF6 GIT1 MARK1 DENND2B CDK13 SRGAP3 RAB11FIP2 ZRANB2	1.06e-05	1256	44	12	int:YWHAE
Interaction	LUC7L interactions	RC3H2 PRPF38B SRSF6 PRPF40A SRRM4 ZRANB2	1.36e-05	242	44	6	int:LUC7L
Interaction	SNIP1 interactions	SRSF6 TMEM184B PRPF40A CDK13 SRRM4 SRSF12 ZRANB2	3.06e-05	417	44	7	int:SNIP1
Interaction	DHX8 interactions	RBM15 CHD1 SRSF6 PRPF40A CDK13 ZRANB2	3.91e-05	292	44	6	int:DHX8
Interaction	SRSF4 interactions	RC3H2 HUWE1 SRSF6 CDK13 SRRM4 SRSF12	4.54e-05	300	44	6	int:SRSF4
Interaction	SREK1 interactions	RC3H2 SRSF6 PRPF40A SRRM4 ZRANB2	4.76e-05	183	44	5	int:SREK1
Interaction	C1orf35 interactions	FLG RC3H2 SRSF6 PRPF40A SRRM4 CCNL1	4.89e-05	304	44	6	int:C1orf35
Interaction	KIF23 interactions	FLG PRPF38B CHD1 HUWE1 SRSF6 TTLL6 PRPF40A PCLO SRSF12 ZRANB2	5.94e-05	1031	44	10	int:KIF23
Interaction	RBMX2 interactions	PRPF40A DCAF5 SRRM4 SRSF12	6.92e-05	101	44	4	int:RBMX2
Interaction	ERC2 interactions	BSN GIT1 PCLO	1.05e-04	42	44	3	int:ERC2
Interaction	CLK1 interactions	RBM15 IP6K1 SRSF6 SRRM4 SRSF12	1.11e-04	219	44	5	int:CLK1
Interaction	LUC7L2 interactions	RC3H2 HUWE1 SRSF6 SRRM4 SRSF12 ZRANB2	1.11e-04	353	44	6	int:LUC7L2
Interaction	CLK3 interactions	RC3H2 RBM15 PRPF38B SRSF6 SRSF12	1.14e-04	220	44	5	int:CLK3
Interaction	SRRM3 interactions	SRRM3 ZRANB2	1.29e-04	8	44	2	int:SRRM3
Interaction	SRPK2 interactions	SDR42E1 RBM15 PRPF38B SRSF6 PRPF40A CDK13 SRSF12 ZRANB2	1.41e-04	717	44	8	int:SRPK2
Interaction	SH3PXD2A interactions	SRGAP2 MARK1 RAB11FIP2 SRSF12	1.73e-04	128	44	4	int:SH3PXD2A
Interaction	DPPA4 interactions	FLG GARIN3 HUWE1 PCLO	2.44e-04	140	44	4	int:DPPA4
Interaction	KIF13B interactions	SRGAP2 CCDC85A RAB11FIP2 SRSF12	2.58e-04	142	44	4	int:KIF13B
Interaction	MARK2 interactions	RC3H2 HUWE1 MARK1 PRPF40A RAB11FIP2	3.15e-04	274	44	5	int:MARK2
Cytoband	Ensembl 112 genes in cytogenetic band chr6q15	GJA10 SRSF12	1.11e-03	51	44	2	chr6q15
Cytoband	7q11.23	SRRM3 POM121C	3.95e-03	97	44	2	7q11.23
Cytoband	3p21.31	IP6K1 BSN	4.19e-03	100	44	2	3p21.31
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF6 SRSF12	1.30e-04	12	26	2	737
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	BSN PCLO	2.06e-04	15	26	2	26
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2 SRGAP3	4.94e-04	23	26	2	1288
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO RAB11FIP2	1.22e-03	36	26	2	823
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	SRGAP2 SRGAP3	2.33e-03	50	26	2	721
GeneFamily	RNA binding motif containing	RBM15 SRSF6 SRSF12	3.43e-03	213	26	3	725
GeneFamily	PDZ domain containing	IL16 PCLO	2.00e-02	152	26	2	1220
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	ZNF816 BSN CSMD2 XKR4 SRRM3 MARK1 SRGAP3 CCDC85A SRRM4 PCLO SRSF12	1.53e-06	1106	44	11	M39071
Coexpression	GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	TRAPPC10 CHD1 SRSF6 TMEM184B RAB11FIP2	1.90e-05	196	44	5	M4244
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	BSN CSMD2 XKR4 SRRM3 MARK1 CCDC85A SRRM4 PCLO	1.94e-05	703	44	8	M39070
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	TRAPPC10 PRPF38B CHD1 IL16 HUWE1 ZNF831 PRPF40A CDK13 SRGAP3 DCAF5 CCNL1	2.63e-05	1492	44	11	M40023
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BSN SRRM3 SRRM4 PCLO	1.83e-05	159	44	4	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 CSMD2 XKR4 SRRM4	1.97e-05	162	44	4	9522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 CSMD2 XKR4 SRRM4	1.97e-05	162	44	4	9a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 CSMD2 XKR4 SRRM4	1.97e-05	162	44	4	40265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 CSMD2 XKR4 SRRM4	1.97e-05	162	44	4	3395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BEST3 CSMD2 SRRM3 SRRM4	2.32e-05	169	44	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CSMD2 XKR4 SRRM3 SRRM4	2.32e-05	169	44	4	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SRRM3 MARK1 SRGAP3 SRSF12	2.43e-05	171	44	4	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BSN ZNF831 MLPH CCDC85A	2.54e-05	173	44	4	12f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BEST3 CSMD2 CCDC85A SRRM4	2.60e-05	174	44	4	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BEST3 CSMD2 CCDC85A SRRM4	2.60e-05	174	44	4	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BEST3 CSMD2 CCDC85A SRRM4	2.60e-05	174	44	4	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	BEST3 CSMD2 CCDC85A SRRM4	2.60e-05	174	44	4	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	15-Distal-Epithelial-Neuroendocrine\|Distal / Age, Tissue, Lineage and Cell class	BEST3 SRRM3 MLPH SRRM4	2.90e-05	179	44	4	bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	BSN SRRM3 SRRM4 PCLO	3.10e-05	182	44	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BSN SRRM4 PCLO SRSF12	3.37e-05	186	44	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BSN SRRM3 SRRM4 PCLO	3.37e-05	186	44	4	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	15-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	BEST3 SRRM3 SRRM4 PCLO	3.44e-05	187	44	4	a7d2f30fe0f19e63d44603ece9890acd11b45e52
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BSN SRRM3 SRRM4 PCLO	3.52e-05	188	44	4	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	BEST3 SRRM3 SRRM4 PCLO	3.52e-05	188	44	4	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPF38B CHD1 PRPF40A CCNL1	3.52e-05	188	44	4	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BSN SRRM3 SRRM4 PCLO	3.67e-05	190	44	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BEST3 XKR4 CCDC85A SRRM4	3.74e-05	191	44	4	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	11.5-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	BEST3 SRRM3 SRRM4 PCLO	3.74e-05	191	44	4	c1bb3ae5c297f55cdadf5b6e53d5296389d5099e
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BEST3 XKR4 MLPH SRRM4	3.74e-05	191	44	4	19832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BEST3 XKR4 MLPH SRRM4	3.82e-05	192	44	4	4d3a1c267739b1479217144656986972fc86db43
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BEST3 XKR4 SRRM4 PCLO	3.90e-05	193	44	4	8603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	XKR4 SRRM3 SRRM4 PCLO	4.14e-05	196	44	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BEST3 XKR4 SRRM4 PCLO	4.22e-05	197	44	4	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	XKR4 SRRM3 SRRM4 PCLO	4.30e-05	198	44	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	XKR4 SRRM3 SRRM4 PCLO	4.30e-05	198	44	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	XKR4 SRRM3 SRRM4 PCLO	4.30e-05	198	44	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	XKR4 SRRM3 SRRM4 PCLO	4.39e-05	199	44	4	47466253069d4b1b8f13ce3210f434e60753b38a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	XKR4 SRRM3 SRRM4 PCLO	4.39e-05	199	44	4	5de2a32bc2e9c752eb19a013b1807949153728fc
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	XKR4 SRRM3 SRRM4 PCLO	4.48e-05	200	44	4	68c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	TRAPPC10 CHD1 CDK13 CCNL1	4.48e-05	200	44	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	XKR4 SRRM3 SRRM4 PCLO	4.48e-05	200	44	4	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal\|6m / Sample Type, Dataset, Time_group, and Cell type.	XKR4 SRRM3 SRRM4 PCLO	4.48e-05	200	44	4	cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	XKR4 SRRM3 SRRM4 PCLO	4.48e-05	200	44	4	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	SRRM3 MLPH SRGAP3 SRRM4	4.48e-05	200	44	4	b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD1 CDK13 CCNL1 ZRANB2	4.48e-05	200	44	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IP6K1 MLPH SRGAP3	4.44e-04	151	44	3	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IP6K1 MLPH SRGAP3	4.44e-04	151	44	3	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GARIN3 BSN SRGAP3	4.70e-04	154	44	3	e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	BSN CSMD2 PCLO	5.25e-04	160	44	3	731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	BSN CSMD2 PCLO	5.25e-04	160	44	3	cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRRM3 TTLL6 SRRM4	5.54e-04	163	44	3	99cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRRM3 TTLL6 SRRM4	5.54e-04	163	44	3	510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	BEST3 CSMD2 XKR4	6.05e-04	168	44	3	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	PRPF38B SRGAP3 CCNL1	6.05e-04	168	44	3	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5\|TCGA-Bladder / Sample_Type by Project: Shred V9	BEST3 BSN SRSF12	6.16e-04	169	44	3	9c4e83fe8225d16173a103bf5a57b17d623be923
ToppCell	facs-Marrow-T-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP2 GJA10 SRSF12	6.26e-04	170	44	3	a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell	facs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP2 GJA10 SRSF12	6.26e-04	170	44	3	ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN SRRM4 PCLO	6.37e-04	171	44	3	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BEST3 SI ZNF831	6.37e-04	171	44	3	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	BEST3 CCDC85A SRRM4	6.59e-04	173	44	3	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	wk_20-22-Epithelial-PNS\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CSMD2 XKR4 ARHGEF10	6.59e-04	173	44	3	17b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	BSN SRRM3 MARK1	6.59e-04	173	44	3	75e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	BSN SRRM3 MARK1	6.59e-04	173	44	3	26e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BEST3 BSN PCLO	6.70e-04	174	44	3	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSMD2 SRRM3 SRRM4	6.81e-04	175	44	3	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSMD2 SRRM3 SRRM4	6.81e-04	175	44	3	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CSMD2 SRRM3 MARK1	6.93e-04	176	44	3	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CSMD2 SRRM3 MARK1	6.93e-04	176	44	3	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN SRRM3 PCLO	7.16e-04	178	44	3	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BEST3 BSN PCLO	7.16e-04	178	44	3	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL16 GIT1 CCDC85A	7.16e-04	178	44	3	60263c0bb9de3a57ba2ba543262a2ace0066fd85
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN SRRM3 PCLO	7.16e-04	178	44	3	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BSN SRRM3 SRRM4	7.27e-04	179	44	3	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRAPPC10 IL16 ZNF831	7.27e-04	179	44	3	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	ARHGEF10 DENND2B CCDC85A	7.39e-04	180	44	3	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRRM3 SRRM4 PCLO	7.51e-04	181	44	3	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BSN GIT1 MLPH	7.63e-04	182	44	3	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	XKR4 SRRM3 SRRM4	7.63e-04	182	44	3	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SRGAP2 ZNF831 SRGAP3	7.75e-04	183	44	3	310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 XKR4 CCDC85A	7.75e-04	183	44	3	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SRGAP2 ZNF831 SRGAP3	7.75e-04	183	44	3	fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 XKR4 SRRM4	7.88e-04	184	44	3	a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SRRM3 SRRM4 PCLO	7.88e-04	184	44	3	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 XKR4 SRRM4	7.88e-04	184	44	3	39c230d32e4259bc784e0edfd9e2884c96898564
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEST3 XKR4 SRRM4	7.88e-04	184	44	3	2a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCell	18-Distal-Epithelial-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	XKR4 SRRM3 PCLO	8.00e-04	185	44	3	d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCell	18-Distal-Epithelial-Neuroendocrine\|Distal / Age, Tissue, Lineage and Cell class	BEST3 SRRM4 PCLO	8.00e-04	185	44	3	f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	XKR4 SRRM3 SRRM4	8.13e-04	186	44	3	2fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 BSN PCLO	8.13e-04	186	44	3	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	wk_15-18-Epithelial-PNS-MFNG+_DBH+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SRRM3 SRRM4 PCLO	8.13e-04	186	44	3	72f7427d62d65e37bb0bf99229a1b75df081a128
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BEST3 XKR4 SRRM4	8.13e-04	186	44	3	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	PCW_07-8.5-Neuronal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CSMD2 XKR4 SRRM4	8.13e-04	186	44	3	7a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD1 PRPF40A CCNL1	8.25e-04	187	44	3	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CHD1 SRSF6 SRGAP3	8.25e-04	187	44	3	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN ZNF831 PCLO	8.25e-04	187	44	3	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN ZNF831 PCLO	8.25e-04	187	44	3	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BSN ZNF831 PCLO	8.25e-04	187	44	3	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD1 HUWE1 CCNL1	8.38e-04	188	44	3	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIT1 ARHGEF10 CCDC85A	8.38e-04	188	44	3	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	MLPH DENND2B PCLO	8.38e-04	188	44	3	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRRM3 SRGAP3 SRRM4	8.38e-04	188	44	3	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	Pericytes-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	CSMD2 MARK1 SRSF12	8.38e-04	188	44	3	14c1c88a944c66f2eaac1ce7526815dcce1f5147
ToppCell	18-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	BEST3 SRRM4 PCLO	8.51e-04	189	44	3	144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BEST3 XKR4 SRRM4	8.64e-04	190	44	3	2375e604eacd38f61f3e661ba2f76d286fcceca7
Disease	parental longevity	IP6K1 BSN SRRM3 POM121C PCLO CCNL1	7.70e-05	494	43	6	EFO_0007796
Disease	cholesteryl ester 22:6 measurement	SRGAP2 SRGAP3	1.00e-03	32	43	2	EFO_0010350
Disease	cysteine-rich with EGF-like domain protein 1 measurement	SRGAP2 SRGAP3	1.00e-03	32	43	2	EFO_0021870
Disease	colorectal adenoma	CSMD2 CCDC85A	1.06e-03	33	43	2	EFO_0005406
Disease	blood molybdenum measurement	XKR4 ARHGEF10	1.41e-03	38	43	2	EFO_0007582
Disease	thioredoxin domain-containing protein 12 measurement	IP6K1 BSN	1.49e-03	39	43	2	EFO_0008298
Disease	skin microbiome measurement	SRGAP2 SRGAP3	1.49e-03	39	43	2	EFO_0801228
Disease	Memory Disorders	CHD1 GIT1	1.80e-03	43	43	2	C0025261
Disease	Memory Loss	CHD1 GIT1	1.80e-03	43	43	2	C0751295
Disease	Age-Related Memory Disorders	CHD1 GIT1	1.80e-03	43	43	2	C0751292
Disease	Memory Disorder, Spatial	CHD1 GIT1	1.80e-03	43	43	2	C0751294
Disease	Memory Disorder, Semantic	CHD1 GIT1	1.80e-03	43	43	2	C0751293
Disease	reading and spelling ability	SRGAP2 SRGAP3 CCDC85A	1.83e-03	166	43	3	EFO_0005301
Disease	Memory impairment	CHD1 GIT1	1.89e-03	44	43	2	C0233794
Disease	Huntington's disease (is_marker_for)	SRSF6 GIT1	2.73e-03	53	43	2	DOID:12858 (is_marker_for)
Disease	blood lead measurement	SRGAP2 SRGAP3	4.19e-03	66	43	2	EFO_0007040
Disease	body fat percentage	IP6K1 SRGAP2 POM121C SRGAP3	5.48e-03	488	43	4	EFO_0007800
Disease	susceptibility to strep throat measurement	CDK13 PCLO	5.52e-03	76	43	2	EFO_0008408
Disease	endometriosis	BSN CALHM3 XKR4	5.90e-03	252	43	3	EFO_0001065
Disease	systemic lupus erythematosus	SRGAP2 ZNF831 POM121C SRGAP3 SRRM4	5.91e-03	799	43	5	MONDO_0007915
Disease	Mental Depression	CSMD2 ARHGEF10 PCLO	6.03e-03	254	43	3	C0011570
Disease	hemoglobin A1 measurement	RC3H2 SRGAP2 SRRM3 SRGAP3	6.84e-03	520	43	4	EFO_0007629
Disease	serum iron measurement	SRGAP2 SRGAP3	7.02e-03	86	43	2	EFO_0006332
Disease	Depressive disorder	CSMD2 ARHGEF10 PCLO	8.59e-03	289	43	3	C0011581
Disease	sunburn	FLG RAB11FIP2	8.67e-03	96	43	2	EFO_0003958
Disease	white matter hyperintensity measurement	ZNF831 DENND2B CCDC85A	9.68e-03	302	43	3	EFO_0005665

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSSVHGSDEHGRLLR	BEST3	111	Q8N1M1
ERRGHSSSGKTCHSP	C2orf16	1866	Q68DN1
GSLSLSHGSSSLEHR	ARHGEF10	1286	O15013
HSRLLSSLSGSHTGE	CSMD2	1681	Q7Z408
DSGSGKAHLRAISSR	CALHM3	281	Q86XJ0
RHLHSDSGSSGSRNS	GJA10	441	Q969M2
SRHTSKLSRHGSGAD	GIT1	581	Q9Y2X7
DRAGHGHSADSSRKS	FLG	666	P20930
GHSADSSRKSGTRHT	FLG	671	P20930
LSGSASRNHHGSSRE	FLG	1286	P20930
SDASHGHSGSRSASR	FLG	2501	P20930
GSRHSGSRHHEASSR	FLG	2526	P20930
ERSHKSKHHGGSRSG	CCNL1	506	Q9UK58
SAFLRGHGSRKESSA	DENND2B	266	P78524
GSLKDRSHSDHRSHS	CHD1	1621	O14646
SEASKSRSRHSHSGE	CDK13	226	Q14004
SGHRKHSSTGDLLSL	RC3H2	976	Q9HBD1
GGGSRRSLHLDKSSS	RBM15	91	Q96T37
RSLHLDKSSSRGGSR	RBM15	96	Q96T37
SRLPRHSDSGSDSKH	BSN	2631	Q9UPA5
SSKSSSEGHLRSHGP	PCLO	4881	Q9Y6V0
ASREHLGSHIRASSS	IL16	821	Q14005
ATDSSRAVHGHSGLK	DCAF5	906	Q96JK2
RHADHSSLTLGSGSS	HUWE1	2521	Q7Z6Z7
KRRRHDSSGSGHSAF	POM121C	316	A8CG34
HHRKRSRSRSGSDSD	PRPF40A	821	O75400
KAHGHGRSSGSRDSE	SDR42E1	351	Q8WUS8
RSEGSPEHSKHRSAS	CCDC85A	241	Q96PX6
HETGAFAHARRGTST	MARK1	636	Q9P0L2
KHSRRSLHRSGSGSD	IP6K1	116	Q92551
SHHSKRRGRASSESQ	MLPH	326	Q9BV36
SHRSASGHKNTRDDK	GARIN3	466	Q8TC56
ESPGRRSHRHSSGSS	SRRM3	246	A6NNA2
HGLSRSHSLSGARDN	TMEM184B	381	Q9Y519
LTRSTFAGSGRHAAH	SI	586	P14410
PKSDRGSHSHSRSRS	SRSF6	251	Q13247
SGTKSRSHGRHSDSI	SRSF12	206	Q8WXF0
CGSTRHSSLGDHKSL	SRGAP3	941	O43295
SHSRSSSKERDHRGS	SRRM5	366	B3KS81
SRSRSHHREGHGSSS	PRPF38B	276	Q5VTL8
SGHGSLNSISRHSSL	SRGAP2	896	O75044
LGATRGHSASHDKDL	SRRM4	86	A7MD48
SNSSGATRASGKHRS	XKR4	231	Q5GH76
RLSSAHSMSDLSGSH	RAB11FIP2	221	Q7L804
HSSNFSRDAHSGSKR	TTLL6	271	Q8N841
RHRSSSGSSHSGSRS	ZRANB2	311	O95218
SRGSVHSACSSEHKG	TRAPPC10	1206	P48553
ASGPSSASSHHKEGR	ZNF831	1571	Q5JPB2
TGSTDRSDHRHAGNK	ZNF816	136	Q0VGE8
KVTRHDGASSDGHLA	NARF	286	Q9UHQ1