Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2C1 ATP2C2 ATP2B2 ATP2B3	1.67e-06	11	172	4	GO:0005388
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ABCA13 TMEM94 ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	4.67e-06	109	172	8	GO:0042626
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	6.20e-06	5	172	3	GO:0030156
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	1.36e-05	36	172	5	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	1.36e-05	36	172	5	GO:0015662
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	TMEM94 ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	1.54e-05	62	172	6	GO:0019829
GeneOntologyMolecularFunction	P-type manganese transporter activity	ATP2C1 ATP2C2	7.38e-05	2	172	2	GO:0140613
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 KIF1A ERCC6L ABCA13 KIF16B ATP2C1 ATP8A1 SMC3 ATP2C2 DNAH8 ATP2B2 ATP2B3 PIF1	1.21e-04	441	172	13	GO:0016887
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA1 ABCA13 TMEM94 ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	1.59e-04	178	172	8	GO:0015399
GeneOntologyMolecularFunction	inositol trisphosphate phosphatase activity	INPP5A INPPL1 SYNJ1	2.13e-04	14	172	3	GO:0046030
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 KIF1A ERCC6L ABCA13 TMEM94 KIF16B ATP2C1 ATP8A1 SMC3 ATP2C2 SHPRH DNAH8 ATP2B2 ATP2B3 PIF1	2.86e-04	614	172	15	GO:0140657
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	PKD1L2 ITPR2 CUL5 ATP2C1 ATP2C2 ATP2B2 ATP2B3	3.40e-04	151	172	7	GO:0015085
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	EEFSEC ABCA1 KIF1A ERCC6L ABCA13 KIF16B AGAP11 RHOH ATP2C1 ATP8A1 SMC3 MTIF2 ATP2C2 DNAH8 ATP2B2 ATP2B3 PIF1	3.94e-04	775	172	17	GO:0017111
GeneOntologyMolecularFunction	apolipoprotein binding	ABCA1 APP LRP4	6.43e-04	20	172	3	GO:0034185
GeneOntologyMolecularFunction	inositol phosphate phosphatase activity	INPP5A INPPL1 SYNJ1	6.43e-04	20	172	3	GO:0052745
GeneOntologyMolecularFunction	pyrophosphatase activity	EEFSEC ABCA1 KIF1A ERCC6L ABCA13 KIF16B AGAP11 RHOH ATP2C1 ATP8A1 SMC3 MTIF2 ATP2C2 DNAH8 ATP2B2 ATP2B3 PIF1	9.54e-04	839	172	17	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	EEFSEC ABCA1 KIF1A ERCC6L ABCA13 KIF16B AGAP11 RHOH ATP2C1 ATP8A1 SMC3 MTIF2 ATP2C2 DNAH8 ATP2B2 ATP2B3 PIF1	9.67e-04	840	172	17	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	EEFSEC ABCA1 KIF1A ERCC6L ABCA13 KIF16B AGAP11 RHOH ATP2C1 ATP8A1 SMC3 MTIF2 ATP2C2 DNAH8 ATP2B2 ATP2B3 PIF1	9.67e-04	840	172	17	GO:0016818
GeneOntologyMolecularFunction	ErbB-3 class receptor binding	ERBB2 ERBB3	1.08e-03	6	172	2	GO:0043125
GeneOntologyCellularComponent	neuromuscular junction	ERBB2 ANK3 TMIGD3 APP LRP4 PRKCQ UNC13A	4.59e-05	112	176	7	GO:0031594
GeneOntologyCellularComponent	ERBB3:ERBB2 complex	ERBB2 ERBB3	7.05e-05	2	176	2	GO:0038143
GeneOntologyCellularComponent	receptor complex	ERBB2 ERBB3 GPR37 ADGRV1 APP NRN1 PLXNB2 ITPR2 PTPRB TLR4 PLXNA4 GPR156 TNFRSF1A TRAV38-1 TRAV19	1.24e-04	581	176	15	GO:0043235
GeneOntologyCellularComponent	semaphorin receptor complex	ERBB2 PLXNB2 PLXNA4	1.58e-04	13	176	3	GO:0002116
GeneOntologyCellularComponent	excitatory synapse	SYNJ1 PLXNA4 BSN ATP2B2 ATP2B3 UNC13A	2.93e-04	107	176	6	GO:0060076
GeneOntologyCellularComponent	cell leading edge	ERBB2 CDC42BPA INPPL1 GDPD2 ADGRV1 APP DCTN1 CDC42BPB KANK1 TLR4 CTNNA3 TLN2 ATP2B2	3.30e-04	500	176	13	GO:0031252
GeneOntologyCellularComponent	synaptic membrane	ERBB2 ERBB3 ANK3 TMIGD3 LRRC4B NBEA IL1RAPL1 SYNJ1 LRP4 GPR156 BSN ATP2B2 ATP2B3 UNC13A	4.35e-04	583	176	14	GO:0097060
Domain	ATPase_P-typ_TM_dom	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.74e-07	16	175	5	IPR023298
Domain	-	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.74e-07	16	175	5	1.20.1110.10
Domain	ATPase_P-typ_cation-transptr_C	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	3.85e-07	17	175	5	IPR006068
Domain	Cation_ATPase_C	TMEM94 ATP2C1 ATP2C2 ATP2B2 ATP2B3	3.85e-07	17	175	5	PF00689
Domain	ATPase_P-typ_transduc_dom_A	TMEM94 ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	1.13e-06	37	175	6	IPR008250
Domain	E1-E2_ATPase	TMEM94 ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	1.13e-06	37	175	6	PF00122
Domain	-	SIGLEC12 OBSCN TMIGD3 LRRC4B PLXNB2 PKHD1L1 IGDCC4 RIMBP3 IL1RAPL1 PTPRB CD22 PLXNA4 CNTN3 RIMBP3C RIMBP3B NFAT5 GPA33 CDON MYBPC1	1.54e-05	663	175	19	2.60.40.10
Domain	ATPase_P-typ_P_site	ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	2.03e-05	36	175	5	IPR018303
Domain	P_typ_ATPase	ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	2.03e-05	36	175	5	IPR001757
Domain	ATPASE_E1_E2	ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	2.03e-05	36	175	5	PS00154
Domain	Cation_ATPase_N	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.06e-05	18	175	4	PF00690
Domain	Cation_ATPase_N	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.06e-05	18	175	4	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.59e-05	19	175	4	IPR004014
Domain	Ig-like_fold	SIGLEC12 OBSCN TMIGD3 LRRC4B PLXNB2 PKHD1L1 IGDCC4 RIMBP3 IL1RAPL1 PTPRB CD22 PLXNA4 CNTN3 RIMBP3C RIMBP3B NFAT5 GPA33 CDON MYBPC1	3.64e-05	706	175	19	IPR013783
Domain	IGc2	SIGLEC12 OBSCN LRRC4B IGDCC4 IL1RAPL1 CD22 CNTN3 GPA33 CDON MYBPC1	7.68e-05	235	175	10	SM00408
Domain	Ig_sub2	SIGLEC12 OBSCN LRRC4B IGDCC4 IL1RAPL1 CD22 CNTN3 GPA33 CDON MYBPC1	7.68e-05	235	175	10	IPR003598
Domain	Ig_I-set	SIGLEC12 OBSCN LRRC4B IGDCC4 IL1RAPL1 CD22 CNTN3 CDON MYBPC1	7.79e-05	190	175	9	IPR013098
Domain	I-set	SIGLEC12 OBSCN LRRC4B IGDCC4 IL1RAPL1 CD22 CNTN3 CDON MYBPC1	7.79e-05	190	175	9	PF07679
Domain	KELK	CDC42BPA CDC42BPB	8.73e-05	2	175	2	IPR031597
Domain	KELK	CDC42BPA CDC42BPB	8.73e-05	2	175	2	PF15796
Domain	P-type_ATPase_IIA_PMR1	ATP2C1 ATP2C2	8.73e-05	2	175	2	IPR006413
Domain	IPPc	INPP5A INPPL1 SYNJ1	9.25e-05	10	175	3	IPR000300
Domain	IPPc	INPP5A INPPL1 SYNJ1	9.25e-05	10	175	3	SM00128
Domain	IPT	PLXNB2 PKHD1L1 PLXNA4 NFAT5	1.10e-04	27	175	4	SM00429
Domain	FN3	OBSCN IGDCC4 RIMBP3 PTPRB CNTN3 RIMBP3C RIMBP3B CDON MYBPC1	1.11e-04	199	175	9	PS50853
Domain	FN3_dom	OBSCN IGDCC4 RIMBP3 PTPRB CNTN3 RIMBP3C RIMBP3B CDON MYBPC1	1.61e-04	209	175	9	IPR003961
Domain	TIG	PLXNB2 PKHD1L1 PLXNA4 NFAT5	1.92e-04	31	175	4	PF01833
Domain	IPT	PLXNB2 PKHD1L1 PLXNA4 NFAT5	2.18e-04	32	175	4	IPR002909
Domain	ATPase_P-typ_cyto_domN	ATP8A1 ATP2C2 ATP2B2 ATP2B3	3.11e-04	35	175	4	IPR023299
Domain	FN3	OBSCN IGDCC4 PTPRB CNTN3 RIMBP3C RIMBP3B CDON MYBPC1	3.62e-04	185	175	8	SM00060
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.17e-04	4	175	2	IPR022141
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	5.17e-04	4	175	2	IPR014930
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3	5.17e-04	4	175	2	PF12424
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	5.17e-04	4	175	2	PD011252
Domain	Tyr_kinase_EGF/ERB/XmrK_rcpt	ERBB2 ERBB3	5.17e-04	4	175	2	IPR016245
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3	5.17e-04	4	175	2	IPR006408
Domain	DMPK_coil	CDC42BPA CDC42BPB	5.17e-04	4	175	2	PF08826
Domain	Helical_ferredxn	DPYD CDON	8.57e-04	5	175	2	IPR009051
Domain	HAD-like_dom	ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	8.78e-04	79	175	5	IPR023214
Domain	GF_recep_IV	ERBB2 ERBB3	1.28e-03	6	175	2	PF14843
Domain	GF_recep_IV	ERBB2 ERBB3	1.28e-03	6	175	2	IPR032778
Domain	ARM-type_fold	PDS5B ARMC3 UBR4 RICTOR NBEA PDCD4 ITPR2 PIK3CD GCN1 TNPO3	1.39e-03	339	175	10	IPR016024
Domain	Vinculin/catenin	CTNNA3 TLN2	1.78e-03	7	175	2	IPR006077
Domain	Recep_L_domain	ERBB2 ERBB3	1.78e-03	7	175	2	PF01030
Domain	Furin-like	ERBB2 ERBB3	1.78e-03	7	175	2	PF00757
Domain	Rcpt_L-dom	ERBB2 ERBB3	1.78e-03	7	175	2	IPR000494
Domain	Furin-like_Cys-rich_dom	ERBB2 ERBB3	1.78e-03	7	175	2	IPR006211
Domain	-	ERBB2 ERBB3	1.78e-03	7	175	2	3.80.20.20
Domain	-	INPP5A INPPL1 SYNJ1	1.79e-03	26	175	3	3.60.10.10
Domain	Exo_endo_phos	INPP5A INPPL1 SYNJ1	1.79e-03	26	175	3	PF03372
Domain	-	ANK3 IRAK2 NOD2 TNFRSF1A CARD14	1.82e-03	93	175	5	1.10.533.10
Domain	C1_1	CDC42BPA CDC42BPB PRKCQ UNC13A	2.00e-03	57	175	4	PF00130
Domain	Endo/exonuclease/phosphatase	INPP5A INPPL1 SYNJ1	2.00e-03	27	175	3	IPR005135
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 BDP1 ERBB2 INTU TUT4 CDC42BPA ANK3 KIF1A UBE4B INPP5A ATG13 VPS13C PCDH11Y WDR70 OBSCN LMBR1 ADGRV1 CPT1A APP INTS8 CDC42BPB ADCY3 JMJD1C CUL5 THAP4 CFAP20DC ATP2C1 PTPRB SHPRH DIP2C FNIP1 RPRD2 NFAT5 PRDM15 GPA33 GOLGB1 NSMAF	1.04e-15	1489	178	37	28611215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 ERBB3 ANK3 KIF1A UBE4B UBR4 RTL10 NBEA DZIP1 APP DCTN1 INTS8 CDC42BPB PAICS JAK1 THAP4 TRIM66 FRY SYNJ1 MTIF2 SIPA1L1 LRP4 FIP1L1 TLN2 ANKRD36 ZMYM5	2.42e-09	1285	178	26	35914814
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB2 ERBB3 GPR37 ADGRV1 APP ITPR2 PTPRB TNFRSF1A	5.42e-08	101	178	8	23382219
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ERBB2 CDC42BPA UBE4B TMEM94 INPPL1 UBR4 WDR70 OBSCN SLC35E2B PLXNB2 DCTN1 BIRC6 CDC42BPB ITPR2 NOD2 SYNJ1 PIK3CD DIP2C LRP4 TLN2 GCN1 TNPO3	6.08e-08	1105	178	22	35748872
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ERBB2 IL16 ERCC6L INPPL1 UBR4 IDH2 KRR1 PLIN2 CUL5 JAK1 THAP4 KANK1 SYNJ1 ZNF483 RIMBP3C RPRD2 PRDM15	1.10e-07	689	178	17	36543142
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	KIF1A TMEM94 UBR4 WDR70 IDH2 PDCD4 FRY NWD2 SYNJ1 MTIF2 SIPA1L1 TLN2 PZP NFAT5	1.84e-07	475	178	14	31040226
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SALL3 ANK3 ATG13 ESRP1 OBSCN RICTOR KRR1 DCTN1 ADCY3 PAICS RHOH POLR3D TCP11L2 SYNJ1 PIK3CD SIPA1L1 TLR4 PLCL2 FAM20B NFAT5 GOLGB1	1.95e-07	1084	178	21	11544199
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PDS5B ERBB2 CDC42BPA TMEM94 INPP5A VPS13C FAM114A2 RICTOR TRIM27 PLXNB2 INTS8 BIRC6 CDC42BPB JAK1 STXBP3 LRP4 PRKCSH	2.01e-07	719	178	17	35337019
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PDS5B INTU UBE4B TMEM94 ATG13 CSMD3 ADCY3 IGDCC4 KANK1 SIPA1L1 PLCL2 FNIP1 NFAT5	2.06e-07	407	178	13	12693553
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PDS5B UBE4B RBBP8 UBR4 ESRP1 INTS8 JMJD1C ITPR2 CUL5 JAK1 PARL FIP1L1	2.20e-07	341	178	12	32971831
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR4 NBEA PLXNB2 NWD2 SYNJ1 TLN2 GCN1	3.38e-07	87	178	7	12465718
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP2C1 ATP8A1 ATP2C2 ATP2B2 ATP2B3	3.57e-07	29	178	5	15071553
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	DPYD ERBB3 ANK3 ABCA13 UBR4 WDR70 PKD1L2 JMJD1C CFAP20DC ASXL3 FIP1L1 TLN2	4.03e-07	361	178	12	26167880
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	CDC42BPA UBR4 SLC35E2B SLC35E2A FAM20B RPRD2	4.34e-07	56	178	6	9455484
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	5.25e-07	4	178	3	19091768
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ERBB2 ERBB3 CDC42BPA ANK3 RICTOR PLXNB2 CDC42BPB ADCY3 JAK1 STXBP3 CD22 ATP2B3	6.37e-07	377	178	12	38117590
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 ERBB2 CDC42BPA VPS13C KIF16B AGAP11 DZIP1 ADGRV1 ARHGAP11A FAM20B LRP4 PLAGL2 RPRD2 BSN	6.69e-07	529	178	14	14621295
Pubmed	Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.	VPS18 KIF1A ATG13 DCTN1 BSN	8.19e-07	34	178	5	25915474
Pubmed	Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals.	ERBB2 ERBB3 APP LRP4	8.66e-07	15	178	4	36765071
Pubmed	IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.	LRRC4B IL1RAPL1 BSN	1.31e-06	5	178	3	21940441
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	1.31e-06	5	178	3	17855024
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	TUT4 TMEM94 PARP4 KANK1 PLAGL2	2.14e-06	41	178	5	8724849
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ADGRV1 BIRC6 CDC42BPB SYNJ1 SIPA1L1 DIP2C TLN2 RPRD2 GCN1	2.64e-06	225	178	9	12168954
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	SIGLEC12 IL16 GPR37 APP STAT4 JAK1 ATP2C1 CD22 TLR4 FAM20B IL17RA C5 C8A TNFRSF1A NFAT5 CARD14	5.86e-06	824	178	16	20237496
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2C1 ATP2B2 ATP2B3	7.24e-06	8	178	3	10951186
Pubmed	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	STAT4 PLCL2 TNFRSF1A TNPO3	9.08e-06	26	178	4	21399635
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BDP1 PDS5B DPYD DCHS2 ANK3 GPR37 OBSCN NBEA PAICS PTPRB SMC3 SHPRH	1.08e-05	497	178	12	36774506
Pubmed	Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.	STAT4 PRKCQ C5	1.08e-05	9	178	3	19674979
Pubmed	Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.	IL16 STAT4 NOD2 JAK1 TLR4 IL17RA C5 TNFRSF1A	1.11e-05	204	178	8	20503287
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	IL16 STAT4 NOD2 JAK1 TLR4 IL17RA C5 TNFRSF1A	1.15e-05	205	178	8	19258923
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ERBB2 ANK3 TMEM94 INPPL1 RICTOR DZIP1 APP PLXNB2 STXBP3 PRKCSH GOLGB1	1.22e-05	421	178	11	36976175
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	IL16 STAT4 NOD2 JAK1 TLR4 IL17RA C5 TNFRSF1A	1.23e-05	207	178	8	17703412
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIF16B OBSCN NBEA IGDCC4 PLXNA4 ANKRD36	1.40e-05	101	178	6	10997877
Pubmed	Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation.	ABCA1 TLR4 TNFRSF1A	1.54e-05	10	178	3	20519121
Pubmed	A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.	PDS5B IL16 AFF2 UBR4 CPT1A PLIN2 DNAH8 GPA33	1.79e-05	218	178	8	19460752
Pubmed	Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.	AFF2 FRY PRKCSH	2.11e-05	11	178	3	12586822
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TUT4 CDC42BPA ANK3 UBR4 RICTOR LRRC4B NBEA IDH2 APP BIRC6 CDC42BPB ATP2C1 SYNJ1 SIPA1L1 TLN2 BSN GCN1 UNC13A	2.45e-05	1139	178	18	36417873
Pubmed	Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations.	NOD2 TLR4	2.60e-05	2	178	2	15770725
Pubmed	Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis.	NOD2 TLR4	2.60e-05	2	178	2	15194649
Pubmed	TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease.	APP TLR4	2.60e-05	2	178	2	21827663
Pubmed	The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.	NOD2 TLR4	2.60e-05	2	178	2	15973118
Pubmed	Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	30068375
Pubmed	MDP-Induced selective tolerance to TLR4 ligands: impairment in NOD2 mutant Crohn's disease patients.	NOD2 TLR4	2.60e-05	2	178	2	19572373
Pubmed	Secretory pathway Ca2+ -ATPases promote in vitro microcalcifications in breast cancer cells.	ATP2C1 ATP2C2	2.60e-05	2	178	2	28618103
Pubmed	Targeting HER2/HER3 co-mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy.	ERBB2 ERBB3	2.60e-05	2	178	2	38441358
Pubmed	Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease.	NOD2 TLR4	2.60e-05	2	178	2	18680223
Pubmed	Genetic association and phenotypic correlation of TLR4 but not NOD2 variants with Tunisian inflammatory bowel disease.	NOD2 TLR4	2.60e-05	2	178	2	29055077
Pubmed	Clustering of (auto)immune diseases with early-onset and complicated inflammatory bowel disease.	NOD2 TLR4	2.60e-05	2	178	2	18670786
Pubmed	Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors.	ERBB2 ERBB3	2.60e-05	2	178	2	12134143
Pubmed	Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia.	IL16 TNFRSF1A	2.60e-05	2	178	2	24736233
Pubmed	HER-2 and HER-3 expression in liver metastases of patients with colorectal cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	25915155
Pubmed	Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas.	ERBB2 ERBB3	2.60e-05	2	178	2	7538656
Pubmed	Seroreactivity to microbial components in Crohn's disease is associated with ileal involvement, noninflammatory disease behavior and NOD2/CARD15 genotype, but not with risk for surgery in a Hungarian cohort of IBD patients.	NOD2 TLR4	2.60e-05	2	178	2	17417801
Pubmed	Intestinal permeability and genetic determinants in patients, first-degree relatives, and controls in a high-incidence area of Crohn's disease in Southern Italy.	NOD2 TLR4	2.60e-05	2	178	2	16393227
Pubmed	Early response to ErbB2 over-expression in polarized Caco-2 cells involves partial segregation from ErbB3 by relocalization to the apical surface and initiation of survival signaling.	ERBB2 ERBB3	2.60e-05	2	178	2	20589763
Pubmed	Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells.	ERBB2 ERBB3	2.60e-05	2	178	2	10799311
Pubmed	Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.	CDC42BPA CDC42BPB	2.60e-05	2	178	2	18263588
Pubmed	The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.	NOD2 TLR4	2.60e-05	2	178	2	30367515
Pubmed	Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.	ATP2C1 ATP2C2	2.60e-05	2	178	2	16332677
Pubmed	TRIM27 regulates the expression of PDCD4 by the ubiquitin‑proteasome pathway in ovarian and endometrial cancer cells.	TRIM27 PDCD4	2.60e-05	2	178	2	35583010
Pubmed	Overexpression and gene amplification of EGFR, HER2, and HER3 in biliary tract carcinomas, and the possibility for therapy with the HER2-targeting antibody pertuzumab.	ERBB2 ERBB3	2.60e-05	2	178	2	25112701
Pubmed	Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis.	APP CNTN3	2.60e-05	2	178	2	31318883
Pubmed	Expression of mutant human epidermal receptor 3 attenuates lung fibrosis and improves survival in mice.	ERBB2 ERBB3	2.60e-05	2	178	2	15731393
Pubmed	Overexpression of ErbB2 and ErbB3 receptors in Schwann cells of patients with Charcot-Marie-tooth disease type 1A.	ERBB2 ERBB3	2.60e-05	2	178	2	16307437
Pubmed	Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium.	NOD2 TLR4	2.60e-05	2	178	2	20580721
Pubmed	H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3.	ERBB2 ERBB3	2.60e-05	2	178	2	20581867
Pubmed	Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	17203234
Pubmed	Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.	ERBB2 ERBB3	2.60e-05	2	178	2	22733765
Pubmed	HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.	ERBB2 ERBB3	2.60e-05	2	178	2	25739551
Pubmed	Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	10205169
Pubmed	In situ detection of HER2:HER2 and HER2:HER3 protein-protein interactions demonstrates prognostic significance in early breast cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	21638049
Pubmed	Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu.	ERBB2 ERBB3	2.60e-05	2	178	2	17638894
Pubmed	Cell-type-specific regulation of genes involved in testicular lipid metabolism: fatty acid-binding proteins, diacylglycerol acyltransferases, and perilipin 2.	FABP12 PLIN2	2.60e-05	2	178	2	23962454
Pubmed	Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome.	ERBB2 ERBB3	2.60e-05	2	178	2	21709195
Pubmed	Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism.	INPPL1 APP	2.60e-05	2	178	2	31664099
Pubmed	Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.	ERBB2 ERBB3	2.60e-05	2	178	2	25017122
Pubmed	Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice.	APP TNFRSF1A	2.60e-05	2	178	2	17724122
Pubmed	The significance of ErbB2/3 in the conversion of induced pluripotent stem cells into cancer stem cells.	ERBB2 ERBB3	2.60e-05	2	178	2	35177646
Pubmed	Green tea extract treatment reduces NFκB activation in mice with diet-induced nonalcoholic steatohepatitis by lowering TNFR1 and TLR4 expression and ligand availability.	TLR4 TNFRSF1A	2.60e-05	2	178	2	28038359
Pubmed	Mutations in innate immune system NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute graft-versus-host disease in patients who underwent an allogeneic transplantation.	NOD2 TLR4	2.60e-05	2	178	2	16436969
Pubmed	Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.	ERBB2 ERBB3	2.60e-05	2	178	2	34171264
Pubmed	Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene.	PDS5B ERBB2	2.60e-05	2	178	2	26334628
Pubmed	CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.	ERBB2 ERBB3	2.60e-05	2	178	2	28805349
Pubmed	Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.	ERBB2 ERBB3	2.60e-05	2	178	2	12000754
Pubmed	Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.	ERBB2 ERBB3	2.60e-05	2	178	2	22248472
Pubmed	Epistatic interaction between TLR4 and NOD2 in patients with Crohn's Disease: relation with risk and phenotype in a Spanish cohort.	NOD2 TLR4	2.60e-05	2	178	2	27290609
Pubmed	Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells.	ERBB2 ERBB3	2.60e-05	2	178	2	26261492
Pubmed	Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies.	ERBB2 ERBB3	2.60e-05	2	178	2	26138066
Pubmed	Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.	ERBB2 ERBB3	2.60e-05	2	178	2	35108525
Pubmed	The ubiquitin ligase UBE4B regulates amyloid precursor protein ubiquitination, endosomal trafficking, and amyloid β42 generation and secretion.	UBE4B APP	2.60e-05	2	178	2	32841720
Pubmed	Maternal TLR4 and NOD2 gene variants, pro-inflammatory phenotype and susceptibility to early-onset preeclampsia and HELLP syndrome.	NOD2 TLR4	2.60e-05	2	178	2	18382655
Pubmed	Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells.	JAK1 TNFRSF1A	2.60e-05	2	178	2	11801527
Pubmed	NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease.	NOD2 TLR4	2.60e-05	2	178	2	16840031
Pubmed	Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.	NOD2 TLR4	2.60e-05	2	178	2	27225947
Pubmed	CARD15 and Toll-like receptor 4 mutations in Italian patients with inflammatory bowel disease.	NOD2 TLR4	2.60e-05	2	178	2	22571967
Pubmed	Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.	CDC42BPA CDC42BPB	2.60e-05	2	178	2	10198171
Pubmed	The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers.	ERBB2 ERBB3	2.60e-05	2	178	2	33907275
Pubmed	Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer.	ERBB2 ERBB3	2.60e-05	2	178	2	22848366
Pubmed	A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.	ERBB2 ERBB3	2.60e-05	2	178	2	18056992
Pubmed	Dual roles of NOD2 in TLR4-mediated signal transduction and -induced inflammatory gene expression in macrophages.	NOD2 TLR4	2.60e-05	2	178	2	21199260
Interaction	SOCS5 interactions	ERBB2 ERBB3 APP CUL5 JAK1	1.59e-06	24	172	5	int:SOCS5
GeneFamily	ATPases Ca2+ transporting	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.67e-07	9	125	4	1209
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SIGLEC12 OBSCN LRRC4B IGDCC4 IL1RAPL1 CNTN3 CDON MYBPC1	1.62e-05	161	125	8	593
GeneFamily	Erb-b2 receptor tyrosine kinases	ERBB2 ERBB3	2.82e-04	4	125	2	1096
GeneFamily	Fibronectin type III domain containing	OBSCN IGDCC4 PTPRB CNTN3 CDON MYBPC1	8.62e-04	160	125	6	555
GeneFamily	Phosphoinositide phosphatases	INPP5A INPPL1 SYNJ1	1.38e-03	32	125	3	1079
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C5 PZP	1.65e-03	9	125	2	1234
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA NSMAF	1.65e-03	9	125	2	1230
GeneFamily	Plexins	PLXNB2 PLXNA4	1.65e-03	9	125	2	683
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	BDP1 TUT4 AFF2 ANK3 KIF1A FAM114A2 RICTOR LRRC4B NBEA CSMD3 ADARB2 INSYN2A FRY ATP8A1 SYNJ1 PIK3CD ASXL3 PLXNA4 TLN2 ANKRD36 BSN ATP2B2 UNC13A CDON	4.68e-07	1106	177	24	M39071
Coexpression	GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_UP	USP53 LMBR1 RICTOR DZIP1 IDH2 JAK1 ATP8A1 ANKRD36 IL17RA	9.76e-07	152	177	9	M343
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	TUT4 UBE4B TMEM94 VPS13C BIRC6 ATP8A1 PIK3CD SIPA1L1 NFAT5	3.95e-06	180	177	9	M8239
Coexpression	GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP	IL16 TUT4 ANK3 SLC35E2B PDCD4 STAT4 RHOH PRKCQ GPA33	8.92e-06	199	177	9	M3087
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2C	VWA3A ERBB3 GDPD2 LRRC4B CSMD3 ITPR2 KANK1 CTNNA3 TNFRSF1A ATP2B2 NEK11	1.41e-05	325	177	11	M39053
Coexpression	FAN_EMBRYONIC_CTX_OLIG	ERBB3 ANK3 KIF1A UBE4B GPR37 INPP5A RICTOR APP DCTN1 IL1RAPL1 FRY ATP8A1 TCP11L2 CD22 CTNNA3 FNIP1 PRKCSH	1.52e-05	754	177	17	M39037
Coexpression	GSE25677_MPL_VS_R848_STIM_BCELL_DN	ABCA1 RICTOR STAT4 JAK1 RHOH FRY SYNJ1 PLCL2	3.34e-05	181	177	8	M8187
Coexpression	GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN	ABCA1 RICTOR STAT4 JAK1 RHOH FRY SMC3 RETNLB	3.61e-05	183	177	8	M8189
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE	ANK3 ATG13 RICTOR KRR1 STAT4 JAK1 RHOH SMC3 FAM20B PRKCQ ANKRD36	3.89e-05	363	177	11	M41103
Coexpression	GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN	KIF16B RICTOR CDC42BPB ITPR2 ATP8A1 SYNJ1 ZMYM5	6.00e-05	145	177	7	M359
Coexpression	GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN	DPYD INPP5A ITPR2 FRY SIPA1L1 TLR4 UPP1 TNFRSF1A	6.09e-05	197	177	8	M8755
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	VWA3A INTU AFF2 ARMC3 KIF1A INPPL1 BDH2 GDPD2 NBEA CSMD3 ITPR2 DLEC1 ATP2B2 NEK11	6.14e-05	600	177	14	M39055
Coexpression	GSE369_IFNG_KO_VS_WT_LIVER_UP	TUT4 SPC25 RICTOR JMJD1C JAK1 PARP4 FAM20B PIF1	6.53e-05	199	177	8	M5970
Coexpression	GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN	RBBP8 STAT4 JAK1 ATP2C1 CD22 PLAGL2 DLEC1 MUC6	6.77e-05	200	177	8	M5232
Coexpression	ZHONG_PFC_C3_ASTROCYTE	DPYD ANK3 OBSCN NBEA CDC42BPB PLXNA4 DIP2C CNTN3 ANKRD36 PRKCSH GCN1	7.24e-05	389	177	11	M39102
Coexpression	GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN	USP53 ERBB3 TRIM27 SHPRH FIP1L1 FNIP1 PRDM15	9.90e-05	157	177	7	M6871
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1	USP53 TUT4 RICTOR DZIP1 ALS2CL BIRC6 PDCD4 STAT4 ITPR2 JAK1 RHOH TCP11L2 PRKCQ DNAH8	7.04e-07	336	173	14	GSM538413_500
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C RICTOR BIRC6 JMJD1C STAT4 ATP2C1 ATP8A1 ANKRD36 NFAT5 GOLGB1	4.24e-09	188	176	10	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 PKD1L2 CSMD3 PKHD1L1 FREM1 ASXL3 TLN2	5.31e-08	184	176	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 PKD1L2 CSMD3 PKHD1L1 FREM1 ASXL3 TLN2	5.31e-08	184	176	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 PKD1L2 CSMD3 PKHD1L1 FREM1 ASXL3 TLN2	5.31e-08	184	176	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VWA3A INTU ANK3 ARMC3 ABCA13 ADGRV1 ATP2C2 DLEC1 PZP	7.99e-08	193	176	9	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	DPYD ANK3 WDR70 ADGRV1 KANK1 ATP8A1 SIPA1L1 DIP2C LRP4	9.11e-08	196	176	9	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWA3A INTU ARMC3 ABCA13 NBEA DLEC1 PZP NEK11	3.82e-07	169	176	8	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB2 ERBB3 ANK3 ABCA13 NBEA ADGRV1 ATP2C2 GOLGB1	5.90e-07	179	176	8	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK3 ESRP1 ADGRV1 IL1RAPL1 ATP8A1 PRKCQ C5 CDON	7.58e-07	185	176	8	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ANK3 ESRP1 ADGRV1 FRY ATP8A1 ATP2C2 CTNNA3	8.90e-07	189	176	8	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 ESRP1 ADGRV1 FRY KANK1 ATP2C2 CTNNA3 C5	9.26e-07	190	176	8	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 ERBB3 TUT4 WDR70 RICTOR ITPR2 TCP11L2 NFAT5	1.00e-06	192	176	8	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 TUT4 WDR70 RICTOR ITPR2 TCP11L2 NFAT5 GOLGB1	1.04e-06	193	176	8	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 ANK3 ESRP1 ADGRV1 KANK1 ATP8A1 ATP2C2 CTNNA3	1.04e-06	193	176	8	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ADGRV1 ASXL3 TLR4 LRP4 CNTN3 IL17RA CDON	1.13e-06	195	176	8	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ADGRV1 ASXL3 TLR4 LRP4 CNTN3 IL17RA CDON	1.13e-06	195	176	8	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	ANK3 ADGRV1 PLXNB2 PLIN2 ATP8A1 PRKCQ C5 GOLGB1	1.22e-06	197	176	8	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Biopsy_Control_(H.)-Immune-Mast_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	LRRC4B FREM1 IL1RAPL1 RHOH CD22 PLXNA4 LRP4 ATP2B2	1.36e-06	200	176	8	64bf125e0e5652a5a638a6bb32eb109cb0d5e232
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANK3 GPR37 DZIP1 APP CTNNA3 PLXNA4 LRP4 PZP	1.36e-06	200	176	8	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD ERBB3 ANK3 GPR37 IL1RAPL1 ATP8A1 CD22 CTNNA3	1.36e-06	200	176	8	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 GPR37 LRRC4B TG IL1RAPL1 FRY CNTN3	3.65e-06	161	176	7	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA13 ADGRV1 CSMD3 PKHD1L1 NWD2 CNTN3 ATP2B3	3.81e-06	162	176	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	10x3'2.3-week_17-19-Neuro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 ERBB3 ANK3 KIF1A GDPD2 IL1RAPL1 CTNNA3	6.32e-06	175	176	7	bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell	10x3'2.3-week_17-19-Neuro-stroma-schwann_cells\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 ERBB3 ANK3 KIF1A GDPD2 IL1RAPL1 CTNNA3	6.32e-06	175	176	7	8b010220cdfb680ec839572f4933adfb85045ea6
ToppCell	10x3'2.3-week_17-19-Neuro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ERBB2 ERBB3 ANK3 KIF1A GDPD2 IL1RAPL1 CTNNA3	6.32e-06	175	176	7	0b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DZIP1 SLC35E2B NRN1 ALS2CL PKHD1L1 RHOH PRKCQ	6.56e-06	176	176	7	218a072882d387adbbad6916d7214099c7354465
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK3 ESRP1 ADGRV1 PLXNB2 ATP8A1 PRKCQ C5	7.33e-06	179	176	7	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 NBEA ADGRV1 ATP2C2 ANKRD36 MUC6 GOLGB1	8.77e-06	184	176	7	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	PDCD4 STAT4 RHOH PIK3CD PLCL2 PRKCQ PZP	9.09e-06	185	176	7	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DZIP1 ALS2CL PDCD4 STAT4 JAK1 PIK3CD PRKCQ	9.41e-06	186	176	7	e23e1246914e230369a716d0d666b98383bf8512
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DZIP1 ALS2CL PDCD4 STAT4 JAK1 PIK3CD PRKCQ	9.41e-06	186	176	7	4dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ESRP1 ADGRV1 FRY KANK1 ATP2C2 PRKCQ	9.41e-06	186	176	7	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ESRP1 ADGRV1 ATP2C2 CTNNA3 PRKCQ C5	9.75e-06	187	176	7	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	Control\|World / Disease state, Lineage and Cell class	ABCA1 INPP5A TMIGD3 IRAK2 PLIN2 SIPA1L1 UPP1	1.04e-05	189	176	7	fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL3 ABCA13 TMEM94 INPP5A IDH2 CPT1A UPP1	1.04e-05	189	176	7	ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	CDC42BPA ANK3 FREM1 FRY KANK1 PRKCQ NFAT5	1.04e-05	189	176	7	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL3 ABCA13 TMEM94 INPP5A IDH2 CPT1A UPP1	1.04e-05	189	176	7	e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCell	COVID-19-T_cells-CD8+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	PDCD4 STAT4 RHOH ATP8A1 PIK3CD PRKCQ PZP	1.04e-05	189	176	7	2c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDCD4 STAT4 RHOH PIK3CD PRKCQ PZP GPA33	1.08e-05	190	176	7	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IRAK2 RHOH ATP8A1 CD22 SIPA1L1 ANKRD36 PIF1	1.08e-05	190	176	7	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IRAK2 RHOH ATP8A1 CD22 SIPA1L1 ANKRD36 PIF1	1.08e-05	190	176	7	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IRAK2 RHOH ATP8A1 CD22 SIPA1L1 ANKRD36 PIF1	1.08e-05	190	176	7	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 GDPD2 ADGRV1 CPT1A KANK1 TLR4 LRP4	1.08e-05	190	176	7	b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell	facs-MAT-Fat-3m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 PDCD4 STAT4 RHOH CD22 PIK3CD PRKCQ	1.12e-05	191	176	7	530469909ab0994bece37945e9098359077b0824
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 ESRP1 ADGRV1 KANK1 ATP2C2 CTNNA3 C5	1.12e-05	191	176	7	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	COVID-19-lung-CD8+_T_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDCD4 STAT4 RHOH ATP8A1 PIK3CD PRKCQ PZP	1.12e-05	191	176	7	543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 ESRP1 ADGRV1 KANK1 ATP8A1 ATP2C2 CTNNA3	1.12e-05	191	176	7	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	facs-MAT-Fat-3m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL16 PDCD4 STAT4 RHOH CD22 PIK3CD PRKCQ	1.12e-05	191	176	7	f7a81acb938ce5d383326840dd45f7dd2cf12b1d
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	SALL3 SPC25 PKHD1L1 ITPR2 PTPRB SIPA1L1 PLXNA4	1.16e-05	192	176	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPYD ABCA1 BIRC6 JMJD1C TG SIPA1L1 NFAT5	1.20e-05	193	176	7	779276e775cb2492e8dd36436295a536084a6415
ToppCell	COVID-19-lung-CD8+_T_cells\|lung / Disease (COVID-19 only), tissue and cell type	PDCD4 STAT4 RHOH ATP8A1 PIK3CD PRKCQ PZP	1.20e-05	193	176	7	780e23e2705fc5c1b70e37568b79731ced5038bd
ToppCell	Control-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	ABCA1 INPP5A TMIGD3 IRAK2 PLIN2 SIPA1L1 UPP1	1.24e-05	194	176	7	c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ESRP1 ADGRV1 FRY ATP8A1 ATP2C2 CTNNA3	1.24e-05	194	176	7	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWA3A INTU ARMC3 ABCA13 NBEA DLEC1 NEK11	1.24e-05	194	176	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 KIF1A VPS13C NBEA SYNJ1 FNIP1 GOLGB1	1.28e-05	195	176	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	ABCA1 INPP5A TMIGD3 IRAK2 PLIN2 SIPA1L1 UPP1	1.32e-05	196	176	7	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANK3 RICTOR PDCD4 STAT4 ATP8A1 PRKCQ ANKRD36	1.32e-05	196	176	7	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB2 ERBB3 ESRP1 IDH2 APP ATP2C2 RETNLB	1.41e-05	198	176	7	e8bfae3888b2406b5629b576cb02913b3297337e
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DPYD ANK3 ADGRV1 KANK1 ATP8A1 SIPA1L1 DIP2C	1.41e-05	198	176	7	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	DPYD ANK3 WDR70 NBEA BIRC6 ITPR2 DIP2C	1.46e-05	199	176	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	DPYD INPPL1 UBR4 PLXNB2 TLR4 UPP1 IL17RA	1.46e-05	199	176	7	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	BDP1 ANK3 NBEA CSMD3 FRY ANKRD36 ATP2B2	1.51e-05	200	176	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDCD4 STAT4 RHOH PIK3CD PLCL2 PRKCQ PZP	1.51e-05	200	176	7	02c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ERBB2 ERBB3 ANK3 ABCA13 APP PLXNB2 GOLGB1	1.51e-05	200	176	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 STAT4 RHOH PIK3CD PLCL2 PRKCQ PZP	1.51e-05	200	176	7	e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB2 ERBB3 ANK3 ABCA13 APP PLXNB2 GOLGB1	1.51e-05	200	176	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal\|6m / Sample Type, Dataset, Time_group, and Cell type.	VWA3A ERBB3 ARMC3 TEAD4 SLC2A12 ATP2B3 MYBPC1	1.51e-05	200	176	7	13ec8afea86e4a10599c924871ba4e325b0a8013
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DPYD ERBB3 SALL3 ITPR2 KANK1 LRP4	1.92e-05	139	176	6	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 ADGRV1 CSMD3 NWD2 CNTN3 ATP2B3	2.44e-05	145	176	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	COVID-19-Mast_cells-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	AFF2 NBEA RHOH CD22 DIP2C PZP	3.68e-05	156	176	6	bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ANK3 RICTOR JMJD1C STAT4 ATP8A1 ANKRD36	3.68e-05	156	176	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	VWA3A ARMC3 ABCA13 ATP8A1 ATP2C2 ANKRD36	3.68e-05	156	176	6	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	COVID-19-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	AFF2 NBEA RHOH CD22 DIP2C PZP	3.68e-05	156	176	6	159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VPS18 ABCA13 OBSCN INTS8 FIP1L1 DLEC1	3.95e-05	158	176	6	35f3082109a5930b89d14db3c8fa93148d3a5dd4
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	IL16 PDCD4 FREM1 PLIN2 POLR3D TCP11L2	4.09e-05	159	176	6	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 NBEA ADCY3 STAT4 IL1RAPL1 CNTN3	4.09e-05	159	176	6	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A ADGRV1 TEAD4 PKHD1L1 FREM1 CNTN3	4.24e-05	160	176	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A ADGRV1 TEAD4 PKHD1L1 FREM1 CNTN3	4.24e-05	160	176	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERCC6L SPC25 ARHGAP11A ADARB2 CD22 PIF1	4.86e-05	164	176	6	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERCC6L SPC25 ARHGAP11A ADARB2 CD22 PIF1	4.86e-05	164	176	6	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC4B REN ADCY3 KCNH6 UNC13A PIF1	5.03e-05	165	176	6	9de841c1c95967c562720feba930246debc626fd
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	VWA3A ARMC3 ESRP1 ADGRV1 ATP8A1 DLEC1	5.03e-05	165	176	6	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	VWA3A ARMC3 ESRP1 ADGRV1 ATP8A1 DLEC1	5.03e-05	165	176	6	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NBEA PARP4 RHOH CD22 DIP2C PZP	5.03e-05	165	176	6	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NBEA PARP4 RHOH CD22 DIP2C PZP	5.03e-05	165	176	6	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC4B REN ADCY3 KCNH6 UNC13A PIF1	5.03e-05	165	176	6	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC4B REN ADCY3 KCNH6 UNC13A PIF1	5.03e-05	165	176	6	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NBEA PARP4 RHOH CD22 DIP2C PZP	5.03e-05	165	176	6	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERCC6L SPC25 ARHGAP11A KCNH6 GPA33 PIF1	5.20e-05	166	176	6	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 ESRP1 BDH2 GPR156 TLN2 MUC6	5.20e-05	166	176	6	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 ESRP1 BDH2 GPR156 TLN2 MUC6	5.20e-05	166	176	6	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	LRRC4B PTPRB CD22 ZNF483 PLXNA4 PZP	5.56e-05	168	176	6	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	P28-Epithelial-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ERBB3 ANK3 FABP12 NRN1 ATP8A1 C5	5.56e-05	168	176	6	03c95ad3684caec7a6d581006b237cc5fa230685
ToppCell	Control-Mast_cells\|Control / group, cell type (main and fine annotations)	NBEA PLIN2 RHOH CD22 DIP2C PZP	5.75e-05	169	176	6	fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5\|TCGA-Bladder / Sample_Type by Project: Shred V9	ARMC3 KIF1A KCNV1 KCNH6 BSN UNC13A	5.75e-05	169	176	6	9c4e83fe8225d16173a103bf5a57b17d623be923
Drug	1sqc	ATP2C1 ATP2C2 ATP2B2 ATP2B3	6.37e-07	10	172	4	CID000444279
Drug	2,5-dimethylquinone	ATP2C1 ATP2C2 ATP2B2 ATP2B3	9.96e-07	11	172	4	CID000008718
Drug	1vyq	ATP2C1 ATP2C2 ATP2B2 ATP2B3	1.48e-06	12	172	4	CID004369390
Drug	p-hydroxyhippuric acid	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.97e-06	14	172	4	CID000151012
Drug	orthovanadate	ERBB3 ABCA1 KIF1A KIF16B REN ADCY3 JAK1 ATP2C1 PTPRB PIK3CD ATP2C2 SLC2A12 ATP2B2 ATP2B3	5.97e-06	435	172	14	CID000061672
Drug	AC1L88YH	ATP2C1 ATP2C2 ATP2B2 ATP2B3	6.93e-06	17	172	4	CID000374551
Drug	AC1L1IZE	EEFSEC KIF1A ADARB2 ATP2C1 ATP2C2 DNAH8 ATP2B2 ATP2B3	7.08e-06	131	172	8	CID000004799
Drug	gramicidin s	PAICS ATP2C1 ATP2C2 ATP2B2 ATP2B3	8.32e-06	37	172	5	CID000073357
Drug	0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A	TUT4 KIF1A CPT1A APP PTPRB SYNJ1 CD22 NEK11 CDON	1.68e-05	193	172	9	3693_DN
Drug	linopirdine	ANK3 KCNH6 BSN ATP2B2 ATP2B3	1.77e-05	43	172	5	CID000003932
Drug	Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	TUT4 GPR37 GDPD2 PDCD4 ITPR2 SYNJ1 PLCL2 CARD14 CDON	1.82e-05	195	172	9	4107_UP
Drug	Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A	CDC42BPA KIF1A ATG13 PDCD4 ITPR2 ATP2C2 IL17RA NFAT5 NEK11	1.82e-05	195	172	9	1532_DN
Drug	Bay K 8644	REN ADCY3 NOD2 ATP2C1 PIK3CD ATP2C2 ATP2B2 ATP2B3	1.91e-05	150	172	8	CID000002303
Drug	milrinone	GDPD2 REN ADCY3 ATP2C1 ATP2C2 ATP2B2 ATP2B3 CARD14	1.91e-05	150	172	8	CID000004197
Drug	Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	ABCA1 KIF1A FAM114A2 NBEA CPT1A CDK10 ITPR2 ATP2C1 TLN2	2.06e-05	198	172	9	6687_DN
Drug	Air Pollutants	USP53 DPYD ERBB2 ERBB3 ABCA1 IL16 VPS13C BDH2 LMBR1 OR2T1 NBEA PDCD4 STAT4 ITPR2 TCP11L2 FNIP1 PRKCQ C5 SLC2A12 NEK11	2.11e-05	917	172	20	ctd:D000393
Drug	AC1L25Y6	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.49e-05	23	172	4	CID000015465
Drug	lanthanum chloride hydrate	ATP2C1 ATP2C2 ATP2B2 ATP2B3	2.49e-05	23	172	4	CID000165791
Drug	cyhexatin	ATP2C1 ATP2C2 ATP2B2 ATP2B3	3.51e-05	25	172	4	CID005364545
Drug	N-ethylmaleimide	INTU KIF1A KIF16B IDH2 ADCY3 TG ATP2C1 STXBP3 MTIF2 ATP2C2 CNTN3 ATP2B2 ATP2B3 GOLGB1	3.58e-05	511	172	14	CID000004362
Drug	DB08106	INTU ERBB3 CUL5 C5	4.13e-05	26	172	4	CID016122580
Drug	dodecyl ether	ATP2C1 ATP2C2 ATP2B2 ATP2B3	4.13e-05	26	172	4	CID000020667
Drug	pyrachlostrobin	INTU ABCA1 ERCC6L INPPL1 IDH2 ADGRV1 TEAD4 CPT1A PLXNB2 IGDCC4 PLIN2 ITPR2 PARP4 KANK1 TLR4 LRP4 TNFRSF1A CDON	4.47e-05	811	172	18	ctd:C513428
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; MCF7; HT_HG-U133A	PDS5B ABCA1 ERCC6L UBE4B CPT1A PDCD4 FAM20B DIP2C	4.87e-05	171	172	8	5247_DN
Drug	xenon	AFF2 NOD2 ATP2C1 ATP2C2 ATP2B2 ATP2B3	5.53e-05	88	172	6	CID000023991
Drug	octaethylene glycol	ATP2C1 ATP2C2 ATP2B2 ATP2B3	6.45e-05	29	172	4	CID000078798
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	PDS5B ERBB3 TUT4 GPR37 STXBP3 PLCL2 DIP2C TNFRSF1A	7.27e-05	181	172	8	1791_DN
Drug	geldanamycin; Up 200; 1uM; HL60; HT_HG-U133A	NOD2 KCNH6 ATP2C1 ATP8A1 SIPA1L1 ATP2B2 ATP2B3 MUC6	7.55e-05	182	172	8	2688_UP
Drug	toxaphene	NOD2 ATP2C1 ATP2C2 ATP2B2 ATP2B3	7.69e-05	58	172	5	CID005284469
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A	TEAD4 APP KRR1 ARHGAP11A ADCY3 MKS1 CUL5 KANK1	7.85e-05	183	172	8	6925_DN
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2C1 ATP2C2 ATP2B2 ATP2B3	1.51e-08	6	168	4	DOID:0050429 (implicated_via_orthology)
Disease	juvenile idiopathic arthritis	ABCA13 JMJD1C STAT4 RHOH UPP1	6.61e-05	74	168	5	EFO_0002609
Disease	Fragile X Syndrome	AFF2 APP	9.63e-05	3	168	2	C0016667
Disease	FRAXE Syndrome	AFF2 APP	9.63e-05	3	168	2	C0751157
Disease	FRAXA Syndrome	AFF2 APP	9.63e-05	3	168	2	C0751156
Disease	biliary liver cirrhosis	STAT4 PLCL2 TNFRSF1A TNPO3	1.15e-04	44	168	4	EFO_0004267
Disease	creatinine measurement	EEFSEC INTU OBSCN ADGRV1 PLXNB2 INTS8 BIRC6 ADARB2 FRY RTCA DIP2C FIP1L1 FNIP1 DLEC1 BSN NFAT5	1.91e-04	995	168	16	EFO_0004518
Disease	meningococcal meningitis (is_implicated_in)	NOD2 TLR4	1.92e-04	4	168	2	DOID:0080176 (is_implicated_in)
Disease	Hypereosinophilic syndrome	JAK1 FIP1L1	1.92e-04	4	168	2	C1540912
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A DCTN1	1.92e-04	4	168	2	DOID:0050890 (biomarker_via_orthology)
Disease	Thyroid preparation use measurement	ERBB3 STAT4 TG NOD2 JAK1 RHOH PRKCQ	2.57e-04	217	168	7	EFO_0009933
Disease	Polycystic Kidney - body part	MKS1 PRKCSH	3.19e-04	5	168	2	C1567435
Disease	DNA methylation	DPYD DCHS2 ABCA1 ABCA13 PCDHA4 FABP12 NRN1 FREM1 FRY UBE3D PLXNA4 ATP2B2	4.00e-04	656	168	12	GO_0006306
Disease	opioid dependence	ERBB3 ADGRV1 CSMD3 NWD2 CTNNA3 TLN2 DLEC1	4.36e-04	237	168	7	EFO_0005611
Disease	Malignant neoplasm of breast	DPYD ERBB2 ERBB3 UBR4 KIF16B OBSCN CPT1A ARHGAP11A ALS2CL PDCD4 STAT4 CUL5 SIPA1L1 DIP2C DLEC1 GOLGB1	4.44e-04	1074	168	16	C0006142
Disease	Biliary Tract Neoplasm	ERBB2 IDH2	4.76e-04	6	168	2	C0005426
Disease	GLIOMA SUSCEPTIBILITY 1	ERBB2 IDH2	4.76e-04	6	168	2	C2750850
Disease	autoimmune disease	ERBB3 STAT4 TG JAK1 RHOH RETNLB	4.85e-04	173	168	6	EFO_0005140
Disease	glucose metabolism disease (implicated_via_orthology)	KCNH6 PIK3CD TLR4	5.35e-04	28	168	3	DOID:4194 (implicated_via_orthology)
Disease	smoking cessation	DPYD ANK3 CSMD3 BIRC6 JMJD1C PLCL2 BSN NFAT5	5.76e-04	325	168	8	EFO_0004319
Disease	mammographic density percentage	INTU NBEA ADCY3	5.94e-04	29	168	3	EFO_0006502
Disease	Colorectal Carcinoma	DPYD VPS18 ABCA1 SALL3 ABCA13 OBSCN CSMD3 ADARB2 TLR4 DIP2C PZP DNAH8	7.26e-04	702	168	12	C0009402
Disease	puberty onset measurement	BIRC6 ADARB2 JMJD1C ZNF483 NFAT5	7.63e-04	125	168	5	EFO_0005677
Disease	Autistic Disorder	DPYD KIF1A NBEA CSMD3 JMJD1C IL1RAPL1 CNTN3	7.71e-04	261	168	7	C0004352
Disease	autoimmune thyroid disease	ERBB3 STAT4 TG JAK1 RHOH	7.90e-04	126	168	5	EFO_0006812
Disease	Lung Neoplasms	DPYD ERBB2 ERBB3 ANK3 RICTOR PDCD4 TLR4	8.43e-04	265	168	7	C0024121
Disease	Malignant neoplasm of lung	DPYD ERBB2 ERBB3 ANK3 RICTOR PDCD4 TLR4	8.62e-04	266	168	7	C0242379
Disease	Head and Neck Neoplasms	DPYD ERBB2 ERBB3	8.72e-04	33	168	3	C0018671
Disease	primary biliary cirrhosis	IL16 STAT4 PLCL2 TNFRSF1A TNPO3	1.01e-03	133	168	5	EFO_1001486
Disease	Autoinflammatory disorder	NOD2 TNFRSF1A CARD14	1.04e-03	35	168	3	C3860213
Disease	interleukin 10 measurement	LMBR1 NRN1 JMJD1C FNIP1	1.04e-03	78	168	4	EFO_0004750
Disease	response to serotonin-norephinephrine reuptake inhibitor	ANK3 IRAK2 BIRC6	1.13e-03	36	168	3	EFO_0006325
Disease	Behcet's disease (is_implicated_in)	STAT4 NOD2 TLR4	1.13e-03	36	168	3	DOID:13241 (is_implicated_in)
Disease	age at onset, coronary stenosis	DLEC1 PRKCSH	1.13e-03	9	168	2	EFO_0004847, MONDO_0006715
Disease	familial Mediterranean fever (is_implicated_in)	NOD2 TLR4	1.13e-03	9	168	2	DOID:2987 (is_implicated_in)
Disease	anti-centromere-antibody-positive systemic scleroderma	STAT4 TNPO3	1.13e-03	9	168	2	EFO_0008536
Disease	lung non-small cell carcinoma (is_implicated_in)	ERBB3 IDH2 JAK1 PTPRB TNFRSF1A	1.23e-03	139	168	5	DOID:3908 (is_implicated_in)
Disease	asthma	EEFSEC PDS5B ERBB2 ERBB3 RBBP8 KIF16B CSMD3 JMJD1C NOD2 PLCL2 CTNNA3 PRKCQ	1.29e-03	751	168	12	MONDO_0004979
Disease	rheumatoid arthritis, Crohn's disease	STAT4 NOD2 BSN	1.32e-03	38	168	3	EFO_0000384, EFO_0000685
Disease	cholesteatoma (is_marker_for)	STAT4 TLR4	1.41e-03	10	168	2	DOID:869 (is_marker_for)
Disease	Head and Neck Carcinoma	ERBB2 ERBB3	1.41e-03	10	168	2	C3887461
Disease	chronic fatigue syndrome (is_marker_for)	IL16 REN	1.41e-03	10	168	2	DOID:8544 (is_marker_for)
Disease	WNT1-inducible-signaling pathway protein 1 measurement	TG C8A	1.41e-03	10	168	2	EFO_0008321
Disease	obesity (implicated_via_orthology)	DCHS2 PLXNB2 STAT4 PLIN2 ITPR2 TLR4	1.50e-03	215	168	6	DOID:9970 (implicated_via_orthology)
Disease	C-reactive protein measurement	DPYD DCHS2 ABCA1 ANK3 UBE4B VPS13C FAM114A2 RICTOR OR8U3 ADCY3 JAK1 TNFRSF1A BSN NFAT5 GCN1 TNPO3	1.50e-03	1206	168	16	EFO_0004458
Disease	Leukoencephalopathy	DPYD APP	1.71e-03	11	168	2	C0270612
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA CDC42BPB	1.71e-03	11	168	2	DOID:0060669 (implicated_via_orthology)
Disease	gallbladder neoplasm	ERBB2 ERBB3	1.71e-03	11	168	2	C0016978
Disease	level of Sterol ester (27:1/20:5) in blood serum	CPT1A NWD2	1.71e-03	11	168	2	OBA_2045197
Disease	Malignant neoplasm of gallbladder	ERBB2 ERBB3	1.71e-03	11	168	2	C0153452
Disease	Bipolar Disorder	ERBB3 ANK3 ABCA13 REN APP ADCY3 NOD2 TLR4 DNAH8	1.72e-03	477	168	9	C0005586
Disease	osteoarthritis, hip	TLR4 PLCL2 TLN2 RPRD2	1.92e-03	92	168	4	EFO_1000786
Disease	forced expiratory volume	EEFSEC RBBP8 PLXNB2 ADCY3 JMJD1C PARL PLXNA4 RPRD2 NFAT5 SLC2A12 CDON MYBPC1	1.95e-03	789	168	12	EFO_0004314
Disease	Malignant Head and Neck Neoplasm	DPYD ERBB2 ERBB3	2.02e-03	44	168	3	C0278996
Disease	lymphangioleiomyomatosis (is_marker_for)	RICTOR CPT1A	2.05e-03	12	168	2	DOID:3319 (is_marker_for)
Disease	age at menarche	EEFSEC DPYD SPC25 ADARB2 ADCY3 TRIM66 TLR4 ZNF483 BSN NFAT5	2.23e-03	594	168	10	EFO_0004703
Disease	Adenocarcinoma of large intestine	ERBB2 CDC42BPB PRKCQ NEK11	2.24e-03	96	168	4	C1319315
Disease	chronic obstructive pulmonary disease (is_marker_for)	IL16 TLR4 C5 TNFRSF1A	2.33e-03	97	168	4	DOID:3083 (is_marker_for)
Disease	Alzheimer disease, cognitive decline measurement, Cognitive impairment	PDS5B ADARB2	2.41e-03	13	168	2	EFO_0007710, HP_0100543, MONDO_0004975
Disease	Primary biliary cirrhosis	STAT4 TNFRSF1A TNPO3	2.45e-03	47	168	3	C0008312
Disease	coronary artery disease (is_implicated_in)	ABCA1 NOD2 TLR4 PARL	2.60e-03	100	168	4	DOID:3393 (is_implicated_in)
Disease	smoking status measurement	DPYD ERBB3 CDC42BPA BIRC6 CDC42BPB ADCY3 ATP2C1 TLR4 PLCL2 CTNNA3 PLXNA4 CNTN3 DLEC1 NFAT5 DNAH8	2.69e-03	1160	168	15	EFO_0006527
Disease	neurotic disorder	ASXL3 SIPA1L1 TLR4 PLCL2	2.70e-03	101	168	4	EFO_0004257
Disease	Vitiligo	STAT4 TG IL1RAPL1 RHOH	2.70e-03	101	168	4	EFO_0004208
Disease	respiratory quotient	INTU UNC13A	2.80e-03	14	168	2	EFO_0005189
Disease	median neuropathy (biomarker_via_orthology)	ERBB2 ERBB3	2.80e-03	14	168	2	DOID:571 (biomarker_via_orthology)
Disease	urate measurement, bone density	UBE4B INPP5A FREM1 ITPR2 TG THAP4 PLXNA4 SLC2A12 DNAH8 ATP2B2	3.00e-03	619	168	10	EFO_0003923, EFO_0004531
Disease	neuroimaging measurement	DCHS2 ERBB3 CDC42BPA ANK3 SPC25 PLXNB2 JMJD1C PLIN2 TG JAK1 SYNJ1 TLR4 TLN2 PRKCSH	3.31e-03	1069	168	14	EFO_0004346
Disease	estradiol measurement	INTU RBBP8 KCNV1 JAK1	3.66e-03	110	168	4	EFO_0004697
Disease	ovarian cancer (is_implicated_in)	ERBB2 NOD2 JAK1	4.03e-03	56	168	3	DOID:2394 (is_implicated_in)
Disease	Benign neoplasm of stomach	ERBB2 ERBB3	4.14e-03	17	168	2	C0153943
Disease	allergic rhinitis (is_marker_for)	NOD2 TLR4	4.14e-03	17	168	2	DOID:4481 (is_marker_for)
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB2 ERBB3	4.14e-03	17	168	2	C0496905
Disease	Renal Insufficiency	IDH2 TLR4	4.14e-03	17	168	2	C1565489
Disease	Antibody Deficiency Syndrome	C5 C8A	4.14e-03	17	168	2	C0003257
Disease	Carcinoma in situ of stomach	ERBB2 ERBB3	4.14e-03	17	168	2	C0154060
Disease	acute kidney failure (is_marker_for)	REN TNFRSF1A	4.14e-03	17	168	2	DOID:3021 (is_marker_for)
Disease	Fetal Alcohol Syndrome	ANK3 ERCC6L	4.14e-03	17	168	2	C0015923
Disease	Drug habituation	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0013170
Disease	Drug abuse	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0013146
Disease	Prescription Drug Abuse	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C4316881
Disease	Substance-Related Disorders	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0236969
Disease	Drug Use Disorders	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0013222
Disease	Drug Dependence	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C1510472
Disease	Substance Dependence	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0038580
Disease	Substance Use Disorders	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CSMD3 ADARB2 CTNNA3 DNAH8	4.29e-03	115	168	4	C0029231
Disease	coronary artery calcification	BDP1 ABCA1 ANK3 SPC25 LRRC4B CPT1A FRY SIPA1L1	4.40e-03	450	168	8	EFO_0004723
Disease	sleep apnea measurement	NBEA KCNV1 CFAP20DC DLEC1	4.43e-03	116	168	4	EFO_0007817
Disease	Substance abuse problem	CSMD3 ADARB2 CTNNA3 DNAH8	4.43e-03	116	168	4	C0740858
Disease	caudal middle frontal gyrus volume measurement	FRY NSMAF	4.64e-03	18	168	2	EFO_0010290
Disease	omega-3 polyunsaturated fatty acid measurement	ABCA1 WDR70 CPT1A JMJD1C	4.70e-03	118	168	4	EFO_0010119
Disease	Schizophrenia	DPYD ERBB3 ABCA1 ANK3 ABCA13 INPP5A NRN1 ALS2CL KCNH6 TLR4 PLCL2 TNFRSF1A	4.81e-03	883	168	12	C0036341
Disease	Sjogren syndrome	STAT4 NFAT5 TNPO3	4.89e-03	60	168	3	EFO_0000699
Disease	rheumatoid arthritis	ERBB3 STAT4 CUL5 CFAP20DC PLCL2 PRKCQ C5 TNPO3	5.14e-03	462	168	8	EFO_0000685
Disease	cutaneous melanoma	GPR37 ADGRV1 PLXNB2 CDK10	5.14e-03	121	168	4	EFO_0000389
Disease	peripheral arterial disease, traffic air pollution measurement	ABCA1 IL16 NBEA ITPR2 CNTN3	5.17e-03	194	168	5	EFO_0004265, EFO_0007908
Disease	diet measurement, HOMA-B	PLXNA4 NFAT5	5.17e-03	19	168	2	EFO_0004469, EFO_0008111
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB2 ERBB3	5.17e-03	19	168	2	DOID:2876 (is_marker_for)
Disease	limited scleroderma	STAT4 TNPO3	5.17e-03	19	168	2	EFO_1001017

Protein segments in the cluster

Peptide	Gene	Start	Entry
SQVIMADSEICGTKD	UNC13A	101	Q9UPW8
SATECLQKIMTTVDP	ALS2CL	836	Q60I27
ASTQVCTGTDMKLRL	ERBB2	21	P04626
VTGSEAELQEKVSMC	ERBB3	1101	P21860
EVSSLCVTKGAEMET	BDP1	2121	A6H8Y1
VGRSMCVEISLKTSE	ATG13	76	O75143
CVEISLKTSEGDSME	ATG13	81	O75143
EEEKFMIVSVTGQTC	AGAP11	271	Q8TF27
QSECQTSVGTLLAKM	BIRC6	4426	Q9NR09
TSFKETILAECQGMI	CUL5	271	Q93034
KTQGTETITCILMDG	CSMD3	866	Q7Z407
SKLGGETVDMDCTLV	RBBP8	681	Q99708
KFTQSALDCMSVEVG	DCTN1	751	Q14203
KMESLGITSRDITTC	C8A	361	P07357
CGSAMSQSLLKTTQE	APP	341	P05067
SKEICGASLTLSTLM	AFF2	746	P51816
LTSLCNGSKSEEMIQ	ABCA1	191	O95477
SITVKTFGERCAQME	ADGRV1	5256	Q8WXG9
VCVRTTMEQKSTASG	RTL10	56	Q7L3V2
CMSSQTKNVVSGVLF	CPT1A	96	P50416
PTDTSLEKMVCSVLS	ABCA13	301	Q86UQ4
QNSTEIGSFLKMVIC	ABCA13	2726	Q86UQ4
ICGKSLSVNEMTLST	DPYD	256	Q12882
LTATIRCTKEMEGDT	ANKRD36	1861	A6QL64
GTKIAASQAISAMCE	ARMC3	331	Q5W041
DGKMVVESTVNSVIC	FABP12	111	A6NFH5
ICSDKTGTLTTNRMT	ATP2B2	496	Q01814
CSDKTGTLTTNRMTV	ATP2B3	471	Q16720
VICSDKTGTLTKNEM	ATP2C1	346	P98194
LCSDKTGTLTANEMT	ATP2C2	376	O75185
IFSDKTGTLTCNVMQ	ATP8A1	406	Q9Y2Q0
ACNISMLKTIQGTDT	ASXL3	1276	Q9C0F0
ESGTCSKMELIDDNT	ESRP1	211	Q6NXG1
VSGQSVVMECVASAD	IGDCC4	256	Q8TDY8
VISEGCSTSADTMKD	KIF16B	1136	Q96L93
SAVLSKNGDCIIATM	NWD2	1236	Q9ULI1
CMASLQEISGSIVKL	NWD2	1266	Q9ULI1
IEQEKTFSSMTCASG	PZP	916	P20742
MSSIICEGDTVSQEL	PDS5B	181	Q9NTI5
EGKNKAMSTCTTRVI	OR4N4C	231	A0A096LPK9
LGEQLITMSCTDKIA	ADARB2	546	Q9NS39
KVSVRTMSLCGESLD	RIMBP3B	1161	A6NNM3
KVSVRTMSLCGESLD	RIMBP3C	1161	A6NJZ7
SSTAGLKVKTEEMQC	INTS8	236	Q75QN2
MVSKDTGKCILTTSE	INSYN2A	1	Q6ZSG2
LMTVTCFEKSEQVQG	JAK1	476	P23458
EKCVTESIMNIVSGF	ITPR2	1476	Q14571
ETKGCSLEQISMELA	SLC2A12	551	Q8TD20
EEITFKGCMANVTVT	MUC6	2356	Q6W4X9
GILMEKSTGNETNTC	OTOP3	261	Q7RTS5
MVESNSKIIVLCSRG	IL17RA	436	Q96F46
VTVSCVSGELSAQKM	PTPRB	356	P23467
ILTTVQCMSSVEGRK	OR2T1	271	O43869
IAKCTGSAINSRETM	PRKCQ	206	Q04759
ECSVSLMSDLEGNTK	GPA33	116	Q99795
DDISIVKTGMDCGLS	MTIF2	681	P46199
TASLCSRKTGVENVM	IRAK2	436	O43187
VRLLCGKETMVTSTT	PRKCSH	481	P14314
DTTMTKIIGNCVSIL	LMBR1	381	Q8WVP7
SAVNTMCNTKTDVIT	JMJD1C	1386	Q15652
GTFSISAVVMEKSVC	KIAA1109	2516	Q2LD37
TNSEKVFSICVMLIG	KCNH6	486	Q9H252
MSSVGIQTISDCSVQ	BSN	2661	Q9UPA5
DTTTGKIVAFMCILS	KCNV1	401	Q6PIU1
KLLSDLCGTVMSTTD	PDCD4	221	Q53EL6
CNTTSSDEVLEMKVS	PLXNA4	1006	Q9HCM2
FVGAERCTMKTLTET	PLXNB2	1131	O15031
SVVETLCTKATMQTV	INPP5A	241	Q14642
CMKVSISLTVGENDT	IL1RAPL1	126	Q9NZN1
EGKNKAMSTCTTRVI	OR4N4	231	Q8N0Y3
CSSEIKRQVVETMGL	DNAH8	3001	Q96JB1
STTNKITAEDCTMEV	FIP1L1	206	Q6UN15
ITVCEGQMKELDSSI	FREM1	1156	Q5H8C1
TVCTVTLEKMSAGLG	IL16	1231	Q14005
GCTSLDTKTITTMAE	NEK11	536	Q8NG66
MDLVDTCVGTSVETN	KANK1	531	Q14678
TLDLIEGSMTVCTTK	KRR1	91	Q13601
TVTALTDCQEGAKDM	NRN1	76	Q9NPD7
KTAECGATVFETDVM	GDPD2	246	Q9HCC8
QGVCIGLSEIMKSTS	GCN1	1981	Q92616
SCLKMNDDGTVQSSV	CDC42BPB	221	Q9Y5S2
DCKAVISTMEGSSLD	PARP4	811	Q9UKK3
KAMQVESCSSAVGVS	NFAT5	101	O94916
DCGSMSTVVSTKTIK	RICTOR	1251	Q6R327
AASMSGKTSLICTQE	LRRC70	506	Q7Z2Q7
DKMETLSVTACSGLS	PKD1L2	341	Q7Z442
TQAMAKVALGDTCVE	PKD1L2	856	Q7Z442
QLSCLSGETDVMVTA	DCHS2	3141	Q6V1P9
CDMLENVTGTQVTSS	INTU	351	Q9ULD6
VQAEAGTTAMLSCEV	OBSCN	1176	Q5VST9
DKDMGVNGLVTCSLT	PCDHA4	376	Q9UN74
GSTQCSLDSVMDKKI	RETNLB	21	Q9BQ08
LACSMSTNEDGIKIV	CTNNA3	431	Q9UI47
VCVETVESGAMTKDL	IDH2	401	P48735
EMIENCSSTTAKLAV	GPR37	371	O15354
SGLMETSKLTECLAG	CARD14	116	Q9BXL6
VSNLLMTDKGCVKTA	CDK10	166	Q15131
SSKELLGISDECQMI	FNIP1	636	Q8TF40
CVKMSAVEGICTSES	C5	856	P01031
GESEFSNVMICETKV	CDON	911	Q4KMG0
MELCTKGLGSQTESL	DIP2C	1236	Q9Y2E4
ISQSTMDCLKGEFDV	ADCY3	456	O60266
ITDKIEAVMTSCQGL	ANK3	3741	Q12955
TTCLTTAGVKEMADV	FAM114A2	436	Q9NRY5
ASCLDKLGDQTAMIT	NSMAF	156	Q92636
CLQILSVSMTVTGKD	GPR156	191	Q8NFN8
VGSNQSLTEICTKLM	FRY	2966	Q5TBA9
ESTMVVEGVLGEKSC	DLEC1	1721	Q9Y238
EKQLSTMRVDVCSTE	RPRD2	211	Q5VT52
DSVMSCQQLTGLKSV	SALL3	851	Q9BXA9
VCMVQTGVDSVSSAA	CNTN3	576	Q9P232
VMEGKSATLTCESDA	CD22	606	P20273
VEELCTNSSLGMEKS	ERCC6L	821	Q2NKX8
SRDSKCIIQMSGSTT	KIF1A	21	Q12756
AELKCRTGTSMTSVN	LRRC4B	381	Q9NT99
ETGNITLMEKCDVTD	PCDH11Y	761	Q9BZA8
ASGAIMTVLAAVCTK	PARL	276	Q9H300
KSQGMTLDCVEISLG	PIF1	556	Q9H611
ELSEFTTVVGNTMCT	UPP1	196	Q16831
MSCEESNIGAISKSS	ARHGAP11A	906	Q6P4F7
LGKVTLDVTMGTACS	POLR3D	341	P05423
MASGSVAECLQQETT	TRIM27	1	P14373
VFGKTLICRSMEVST	SMC3	626	Q9UQE7
SIGIQTCVEVNKTLM	TCP11L2	391	Q8N4U5
VTGCMSVGKIQESEV	SYNJ1	81	O43426
KVSVRTMSLCGESLD	RIMBP3	1161	Q9UFD9
ELCGKTFSERNTMET	PRDM15	1171	P57071
MLSSIKCVLVGDSAV	RHOH	1	Q15669
MKGVSVGSSTLLCED	REN	271	P00797
ELLIEGLVCMKSSTS	NBEA	1921	Q8NFP9
GLVCMKSSTSVVELV	NBEA	1926	Q8NFP9
ASDCINSMVEGSELK	PLCL2	136	Q9UPR0
RLQFVSKGCESVEMT	SIPA1L1	941	O43166
ECVVALKSMIGSTAQ	INPPL1	836	O15357
DSGITDVAMSKSTCI	SHPRH	606	Q149N8
QMLSTTVIGCVKTLV	SLC35E2A	111	P0CK97
KAISTCGSHMVTVTI	OR8U3	236	Q8NH85
ASCCKMTDLLEEGIT	STXBP3	46	O00186
GSCLKLMEDGTVQSS	CDC42BPA	221	Q5VT25
LTMQKSVTVQEGLCV	SIGLEC12	26	Q96PQ1
QCSVSQMDTLSTGEV	DZIP1	616	Q86YF9
MLGLLSCSSTVSVKE	PLAGL2	256	Q9UPG8
KSTDTSCQMAGLRDT	SPC25	21	Q9HBM1
MSSVASSVKGVVNRC	BDH2	131	Q9BUT1
TVEKCVNGTEMSALL	CFAP20DC	176	Q6ZVT6
DCGIMDGKTVTSTDV	TPPP2	36	P59282
TVMDISGVKETVCFS	USP53	711	Q70EK8
KSESQCRVVVLMGST	PAICS	261	P22234
VIDVTKGMQTQSAEC	EEFSEC	116	P57772
LSGVTQTCTTKSLAM	MKS1	351	Q9NXB0
TMCIQASEGKDSSVA	NOD2	646	Q9HC29
AETMKETSLGRLSCV	TMEM94	661	Q12767
VLCGTNVKAMSIEES	STAT4	376	Q14765
KGEFMTCSNDATVRT	WDR70	296	Q9NW82
SRSQSMDIDGVSCEK	UBE4B	101	O95155
VSCEKSMSQVDVDSG	UBE4B	111	O95155
RCKVMLGETVSSETT	UBE3D	211	Q7Z6J8
SVLATVKQCTDQFGM	FAM20B	381	O75063
VVSSNQLCMSLGKDT	VPS18	61	Q9P253
ADTKTAGSVCLLMQV	RTCA	91	O00442
IESSVEVKGCTAMIG	TEX101	176	Q9BY14
NEMLCKTVSSSEVSV	PIK3CD	351	O00329
DGSMNVSVKLKTCTL	VPS13C	1986	Q709C8
QMLSTTVIGCVKTLV	SLC35E2B	111	P0CK96
CEVSVVNGKDLSQSM	PKHD1L1	2066	Q86WI1
ESPENMIITCSTKVC	TEAD4	321	Q15561
IASICVVSSMAQKVT	TRAV19	11	A0A0A6YYK7
VSLLMTCVEKAGTDE	TNPO3	181	Q9Y5L0
MEKCSVGGLELTEQT	ZMYM5	1	Q9UJ78
VGCAITTISSNLTEM	TLN2	576	Q9Y4G6
KMVTVCPNTESCESI	ZNF483	156	Q8TF39
VCEMAENGVKTITSV	PLIN2	46	Q99541
QLIVTMSCLTKEDTG	TMIGD3	136	P0DMS9
IIECGTESSSMSIKV	TRIM66	896	O15016
MATNGCILLGETTEK	TUT4	741	Q5TAX3
GTESETKAFMAVCIE	UBR4	4301	Q5T4S7
TCQMNKTIIGVSVLS	TLR4	626	O00206
GDVMETVLSSQTCEQ	TG	596	P01266
RKEMGQVEISSCTVD	TNFRSF1A	106	P19438
MSINEVILSASGACK	THAP4	326	Q8WY91
LTCTMEEISTEITNG	VWA3A	366	A6NCI4
LESKVCILLDTSGSM	VWA3A	956	A6NCI4
VVSTCLESGMAQTVT	TRAV38-1	11	A0A0B4J264
AGDTAKECMETLLSS	GOLGB1	1706	Q14789
VCMKTDTVSIQASSG	LRP4	1841	O75096
CGLSEDATMTKESAV	MYBPC1	1011	Q00872