Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5-diphosphoinositol pentakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

1.71e-052832GO:0033857
GeneOntologyMolecularFunctioninositol hexakisphosphate 3-kinase activity

PPIP5K1 PPIP5K2

1.02e-044832GO:0052724
GeneOntologyMolecularFunctioninositol hexakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

1.02e-044832GO:0052723
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK2 GRK3

1.02e-044832GO:0047696
GeneOntologyMolecularFunctioninositol hexakisphosphate 5-kinase activity

PPIP5K1 PPIP5K2

1.69e-045832GO:0000832
GeneOntologyMolecularFunctiondiphosphoinositol pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.69e-045832GO:0000829
GeneOntologyMolecularFunctioninositol hexakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.69e-045832GO:0000828
GeneOntologyMolecularFunctioninositol-1,3,4,5,6-pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.69e-045832GO:0000827
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK2 GRK3

3.54e-047832GO:0004703
GeneOntologyMolecularFunctioninositol phosphate kinase activity

PPIP5K1 PPIP5K2

9.16e-0411832GO:0180030
GeneOntologyMolecularFunctionkinase activity

NEK4 PIKFYVE JAK3 SMG1 GRK2 GRK3 PIK3C2A PPIP5K1 PPIP5K2 PXK

1.24e-037648310GO:0016301
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

NEK4 PIKFYVE JAK3 SMG1 GRK2 GRK3 PIK3C2A POLI PPIP5K1 PPIP5K2 PXK

1.69e-039388311GO:0016772
DomainTF_POU_3

POU3F1 POU3F2 POU3F3

2.90e-074793IPR016362
DomainPOU

POU3F1 POU3F2 POU3F3

3.92e-0516793SM00352
DomainPOU_2

POU3F1 POU3F2 POU3F3

3.92e-0516793PS00465
DomainPOU_dom

POU3F1 POU3F2 POU3F3

3.92e-0516793IPR000327
DomainPOU_3

POU3F1 POU3F2 POU3F3

3.92e-0516793PS51179
DomainPou

POU3F1 POU3F2 POU3F3

3.92e-0516793PF00157
DomainPOU_1

POU3F1 POU3F2 POU3F3

3.92e-0516793PS00035
DomainPOU

POU3F1 POU3F2 POU3F3

4.75e-0517793IPR013847
DomainNUT

NUTM2B NUTM2A

1.75e-045792IPR024310
DomainNUT_N

NUTM2B NUTM2A

1.75e-045792IPR024309
DomainNUT

NUTM2B NUTM2A

1.75e-045792PF12881
Domain-

POU3F1 POU3F2 POU3F3

1.98e-04277931.10.260.40
DomainLambda_DNA-bd_dom

POU3F1 POU3F2 POU3F3

2.46e-0429793IPR010982
DomainAcid_Pase_AS

PPIP5K1 PPIP5K2

2.62e-046792IPR033379
DomainHIS_ACID_PHOSPHAT_2

PPIP5K1 PPIP5K2

3.66e-047792PS00778
DomainGPCR_kinase

GRK2 GRK3

3.66e-047792IPR000239
DomainHIS_ACID_PHOSPHAT_1

PPIP5K1 PPIP5K2

3.66e-047792PS00616
DomainHis_Pase_clade-2

PPIP5K1 PPIP5K2

4.87e-048792IPR000560
DomainHis_Phos_2

PPIP5K1 PPIP5K2

4.87e-048792PF00328
DomainLipase/vitellogenin

PNLIPRP2 LPL

7.78e-0410792IPR013818
DomainTAG_lipase

PNLIPRP2 LPL

7.78e-0410792IPR000734
DomainLipase_LIPH

PNLIPRP2 LPL

7.78e-0410792IPR016272
DomainLipase

PNLIPRP2 LPL

7.78e-0410792PF00151
DomainLipase_N

PNLIPRP2 LPL

7.78e-0410792IPR033906
DomainZF_THAP

THAP2 THAP9

1.13e-0312792PS50950
DomainDM3

THAP2 THAP9

1.13e-0312792SM00692
DomainTHAP

THAP2 THAP9

1.13e-0312792SM00980
DomainTHAP

THAP2 THAP9

1.13e-0312792PF05485
DomainZnf_C2CH

THAP2 THAP9

1.13e-0312792IPR006612
DomainDUF4599

SPATA31D4 SPATA31D3

1.13e-0312792PF15371
DomainDUF4599

SPATA31D4 SPATA31D3

1.13e-0312792IPR027970
DomainZINC_FINGER_C2H2_2

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF280C ZNF714 ZNF687 PRDM1

1.55e-037757910PS50157
DomainZINC_FINGER_C2H2_1

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF280C ZNF714 ZNF687 PRDM1

1.58e-037777910PS00028
DomainPI3/4_kinase_CS

SMG1 PIK3C2A

1.79e-0315792IPR018936
DomainZnf_C2H2-like

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF280C ZNF714 ZNF687 PRDM1

1.88e-037967910IPR015880
Domain-

SMG1 PIK3C2A

2.04e-03167921.10.1070.11
DomainPI3Kc

SMG1 PIK3C2A

2.04e-0316792SM00146
DomainZnf_C2H2

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF280C ZNF714 ZNF687 PRDM1

2.04e-038057910IPR007087
DomainZnF_C2H2

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF280C ZNF714 ZNF687 PRDM1

2.10e-038087910SM00355
Domainzf-C2H2

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF714 ZNF687 PRDM1

2.57e-03693799PF00096
DomainLH2

PNLIPRP2 LPL

2.59e-0318792SM00308
DomainPI3/4_kinase_cat_dom

SMG1 PIK3C2A

2.59e-0318792IPR000403
DomainPI3_PI4_kinase

SMG1 PIK3C2A

2.59e-0318792PF00454
DomainPI3_4_KINASE_3

SMG1 PIK3C2A

2.59e-0318792PS50290
DomainPI3_4_KINASE_1

SMG1 PIK3C2A

2.59e-0318792PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3C2A

2.59e-0318792PS00916
DomainZnf_C2H2/integrase_DNA-bd

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF714 ZNF687 PRDM1

2.59e-03694799IPR013087
DomainHis_PPase_superfam

PPIP5K1 PPIP5K2

3.19e-0320792IPR029033
Domain-

PPIP5K1 PPIP5K2

3.19e-03207923.40.50.1240
DomainPLAT

PNLIPRP2 LPL

3.52e-0321792PS50095
Domain-

PNLIPRP2 LPL

3.52e-03217922.60.60.20
DomainPLAT

PNLIPRP2 LPL

3.52e-0321792PF01477
DomainPLAT/LH2_dom

PNLIPRP2 LPL

3.52e-0321792IPR001024
DomainLIPASE_SER

PNLIPRP2 LPL

5.38e-0326792PS00120
Pubmed

Structure and evolution of four POU domain genes expressed in mouse brain.

POU3F1 POU3F2 POU3F3

5.83e-0848631565620
Pubmed

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

POU3F1 POU3F2 POU3F3

5.83e-08486326265007
Pubmed

The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

POU3F1 POU3F2 POU3F3

1.45e-0758639105675
Pubmed

Cooperative function of POU proteins and SOX proteins in glial cells.

POU3F1 POU3F2 POU3F3

1.45e-0758639632656
Pubmed

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

POU3F1 POU3F2 POU3F3

2.90e-0768632739723
Pubmed

Hippocampus-like corticoneurogenesis induced by two isoforms of the BTB-zinc finger gene Zbtb20 in mice.

POU3F1 POU3F2 POU3F3

5.07e-07786317301088
Pubmed

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.

POU3F1 POU3F2 POU3F3

1.21e-06986315872005
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

ANK3 LPL POU3F1 POU3F2 POU3F3

1.93e-068286531073041
Pubmed

Murine chromosomal location of four class III POU transcription factors.

POU3F1 POU3F2 POU3F3

3.16e-06128638276397
Pubmed

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

POU3F1 POU3F2 POU3F3

4.10e-06138638543156
Pubmed

Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif.

POU3F1 POU3F2 POU3F3

5.21e-061486317141158
Pubmed

Cloning of GRK2 cDNA from S49 murine lymphoma cells.

GRK2 GRK3

6.04e-0628628638670
Pubmed

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.

PPIP5K1 PPIP5K2

6.04e-06286218981179
Pubmed

Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6.

POU3F1 POU3F3

6.04e-0628628663425
Pubmed

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

GRK2 GRK3

6.04e-06286233060647
Pubmed

G protein--coupled receptor kinases.

GRK2 GRK3

6.04e-0628628035170
Pubmed

Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

PPIP5K1 PPIP5K2

6.04e-06286217702752
Pubmed

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

GRK2 GRK3

6.04e-06286210198406
Pubmed

Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2.

POU3F1 POU3F3

6.04e-0628629457692
Pubmed

G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.

GRK2 GRK3

6.04e-06286211762794
Pubmed

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.

PPIP5K1 PPIP5K2

6.04e-06286228126903
Pubmed

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

PPIP5K1 PPIP5K2

6.04e-06286217690096
Pubmed

Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.

POU3F1 POU3F2 POU3F3

6.50e-061586318255031
Pubmed

The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.

POU3F1 POU3F2 POU3F3

7.99e-06168639118797
Pubmed

Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.

POU3F1 POU3F2 POU3F3

7.99e-061686319527706
Pubmed

Transcriptional regulation of cortical neuron migration by POU domain factors.

POU3F1 POU3F2 POU3F3

1.61e-052086311859196
Pubmed

Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.

GRK2 GRK3

1.81e-05386210754297
Pubmed

PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.

PPIP5K1 PPIP5K2

1.81e-05386231852976
Pubmed

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

NUTM2B NUTM2A

1.81e-05386222456610
Pubmed

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.

GRK2 GRK3

1.81e-05386210085131
Pubmed

JAK3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type.

JAK3 PRDM1

1.81e-05386231002364
Pubmed

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

GRK2 GRK3

1.81e-0538627761854
Pubmed

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.

GRK2 GRK3

1.81e-05386231604529
Pubmed

Class III POU genes: generation of homopolymeric amino acid repeats under GC pressure in mammals.

POU3F2 POU3F3

1.81e-0538628703082
Pubmed

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.

FRMD8 FRMD8P1

1.81e-05386237527040
Pubmed

Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.

GRK2 GRK3

1.81e-05386212130708
Pubmed

The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon.

POU3F2 POU3F3

1.81e-05386216547000
Pubmed

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.

FRMD8 FRMD8P1

1.81e-05386236720499
Pubmed

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.

NUTM2E NUTM2B

1.81e-05386226542179
Pubmed

Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4.

POU3F2 POU3F3

3.61e-05486226951672
Pubmed

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.

GRK2 GRK3

3.61e-05486221784156
Pubmed

Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

POU3F1 POU3F2

3.61e-05486222566684
Pubmed

A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.

POU3F1 POU3F2

3.61e-05486215893976
Pubmed

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.

GRK2 GRK3

3.61e-0548628917529
Pubmed

Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.

GRK2 GRK3

3.61e-0548628662816
Pubmed

Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.

GRK2 GRK3

3.61e-05486223734232
Pubmed

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.

POU3F1 POU3F2 POU3F3

3.64e-052686322992956
Pubmed

FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.

FRMD8 FRMD8P1

6.01e-05586229897336
Pubmed

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

FRMD8 FRMD8P1

6.01e-05586229897333
Pubmed

Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.

GRK2 GRK3

6.01e-05586210338466
Pubmed

The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development.

POU3F1 POU3F2

6.01e-05586212782656
Pubmed

Polysialylation and lipopolysaccharide-induced shedding of E-selectin ligand-1 and neuropilin-2 by microglia and THP-1 macrophages.

GLG1 ST8SIA2

6.01e-05586227159043
Pubmed

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.

POU3F1 POU3F2

9.01e-05686218505825
Pubmed

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

GRK2 GRK3

9.01e-0568629826657
Pubmed

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2.

GRK2 GRK3

9.01e-05686220074556
Pubmed

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

POU3F1 POU3F2

9.01e-05686221185279
Pubmed

Genome-wide association study of bipolar I disorder in the Han Chinese population.

ANK3 ST8SIA2

9.01e-05686220386566
Pubmed

Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo.

POU3F2 POU3F3

9.01e-05686215465489
Pubmed

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

FRMD8 FRMD8P1

9.01e-05686229776906
Pubmed

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.

PIKFYVE PIK3C2A

9.01e-05686222696681
Pubmed

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.

GRK2 GRK3

9.01e-05686236451830
Pubmed

Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

POU3F2 POU3F3

9.01e-05686215262984
Pubmed

The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination.

POU3F1 POU3F3

9.01e-05686215713637
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

NEK4 ANKRD44 GAPVD1 PIK3C2A DOCK11 CUL7 DENND4C

1.22e-0444686724255178
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK2 GRK3

1.26e-0478628672451
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK2 GRK3

1.26e-04786211517230
Pubmed

Genome-wide association study reveals two new risk loci for bipolar disorder.

ANK3 POU3F2

1.68e-04886224618891
Pubmed

POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex.

POU3F2 POU3F3

1.68e-04886222892427
Pubmed

The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse.

POU3F1 POU3F2

1.68e-04886235935334
Pubmed

Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development.

POU3F2 POU3F3

1.68e-04886219147497
Pubmed

Chromosomal organization of mammalian POU domain factors.

POU3F2 POU3F3

2.15e-0498628276396
Pubmed

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.

GRK2 GRK3

2.15e-04986234873237
Pubmed

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.

GRK2 GRK3

2.68e-04108621869533
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SMG1 GAPVD1 SMCHD1 ZNF280C PPIP5K2 ZNF687 GPR107

3.45e-0452986714621295
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

ANK3 SCN3A

3.93e-041286230175250
Pubmed

Expression of Pou3f3/Brn-1 and its genomic methylation in developing auditory epithelium.

POU3F2 POU3F3

3.93e-041286219743445
Pubmed

The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase.

THAP2 THAP9

3.93e-041286212575992
Pubmed

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.

POU3F2 POU3F3

4.63e-041386219403657
Pubmed

Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse.

LPL POU3F1

4.63e-04138628009369
Pubmed

Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.

POU3F1 POU3F2

5.39e-041486215273690
Pubmed

Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.

BANK1 PXK

6.21e-041586220881011
Pubmed

A gene expression atlas of early craniofacial development.

POU3F2 ALDH1A3

7.09e-041686224780627
Pubmed

Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.

BANK1 PXK

7.09e-041686220848568
Pubmed

PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.

POU3F1 POU3F2

1.01e-031986233597191
Pubmed

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

ANK3 POU3F1

1.12e-032086224776795
Pubmed

Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.

POU3F2 POU3F3

1.12e-032086212130536
Pubmed

Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system.

POU3F1 POU3F2

1.23e-032186228880149
Pubmed

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.

PIKFYVE GRK2 GRK3

1.29e-038686326885983
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NEK4 ARFGEF3 GAPVD1 PIK3C2A DOCK11 PPIP5K2 DENND4C E2F8

1.32e-0386186836931259
Pubmed

Genome-wide association study identifies five new schizophrenia loci.

ANK3 PIK3C2A

1.48e-032386221926974
Pubmed

Local regulation of fat metabolism in peripheral nerves.

LPL POU3F1

1.48e-032386214522948
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NEK4 ZNF462 ENAM SMCHD1 LPL E2F8

1.74e-0351386625798074
Pubmed

Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina.

SLITRK6 PRDM1

1.75e-032586228199486
Pubmed

Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion.

POU3F2 POU3F3

1.75e-032586239271675
Pubmed

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.

SFMBT1 JAK3 ANK3

1.87e-039886323898208
Pubmed

Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.

ALDH1A3 E2F8

1.89e-032686216280085
Pubmed

Discovery and refinement of loci associated with lipid levels.

SETD2 FADS3 LPL PXK

1.90e-0321186424097068
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

NEK4 SFMBT1 ANK3

2.10e-0310286321926972
Pubmed

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

ZNF462 CUL7

2.19e-032886225752541
Pubmed

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

MAB21L2 PRDM1

2.19e-032886223595746
InteractionPOU3F4 interactions

POU3F1 POU3F2 POU3F3

1.34e-066833int:POU3F4
InteractionPOU3F3 interactions

POU3F1 POU3F2 POU3F3 ALDH1A3

1.85e-0622834int:POU3F3
Cytoband9q21.32

SPATA31D4 SPATA31D3

5.81e-04198629q21.32
Cytoband19p12

ZNF430 ZNF66 ZNF714

6.63e-049086319p12
Cytoband10q25.3

PNLIPRP2 TRUB1

1.36e-032986210q25.3
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF430 ZNF66 ZNF714

1.60e-03122863chr19p12
Cytoband4q24

GSTCD BANK1

1.87e-03348624q24
Cytoband3p21.1

NEK4 SFMBT1

2.84e-03428623p21.1
Cytoband10q22.3

NUTM2E NUTM2B

2.98e-034386210q22.3
GeneFamilyPOU class homeoboxes and pseudogenes

POU3F1 POU3F2 POU3F3

3.82e-0523523523
GeneFamilyTHAP domain containing

THAP2 THAP9

5.26e-041252265
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF462 ZNF430 ZNF132 ZNF469 ZNF878 ZNF33A ZNF714 PRDM1

9.53e-0471852828
GeneFamilyLipases|Arylacetamide deacetylase family

PNLIPRP2 LPL

1.81e-0322522464
CoexpressionGSE22886_TCELL_VS_BCELL_NAIVE_DN

FADS3 GRK3 P2RX5 CLEC4A SCN3A HYDIN BANK1

3.50e-06198847M4426
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

JAK3 ANKRD44 SMG1 DOCK11 ATAD2B DISP1 DENND4C

3.62e-06199847M9238
CoexpressionZHONG_PFC_C3_ASTROCYTE

ARFGEF3 ANKRD44 FADS3 GRK3 ANK3 ATAD2B LPL SCN3A

3.57e-05389848M39102
CoexpressionGSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN

GAPVD1 STARD8 DOCK11 GLG1 POLI DENND4C

4.54e-05200846M8054
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

ZNF462 ARFGEF3 ANKRD44 FADS3 GRK3 ANK3 SCN3A NUTM2A ST8SIA2 NOX4 POU3F2 HYDIN PXK

4.85e-0511068413M39071
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 MATN2 LPL POU3F1 ALDH1A3 SMOC2

2.21e-07132866ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 MATN2 LPL POU3F1 ALDH1A3 SMOC2

4.33e-07148866d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 MATN2 LPL POU3F2 FAM47E ALDH1A3

5.90e-071568662cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIKFYVE ANKRD44 FADS3 SCN3A BANK1 PXK

1.23e-06177866320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIKFYVE ENAM ANKRD44 P2RX5 SMCHD1 BANK1

1.45e-061828665f1f10c845b73d1f69794277925ef847ff23ac2d
ToppCellmild-B_cell|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ENAM PLA2R1 STARD8 SCN3A ZNF280C BANK1

1.50e-06183866175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIKFYVE ANKRD44 FADS3 SCN3A BANK1 PXK

1.65e-06186866fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCellNS-moderate-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIKFYVE ANKRD44 FADS3 SCN3A BANK1 PXK

1.75e-06188866e9ed34cfea1d93eaa8e63d5b5dbb64f1520d9c4c
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

SFMBT1 JAK3 ANKRD44 ANK3 SMCHD1 PRDM1

1.86e-06190866d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

PIKFYVE GRK3 P2RX5 POU3F3 BANK1 PXK

1.92e-06191866c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 JAK3 ANKRD44 ANK3 SMCHD1 PRDM1

1.98e-06192866253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 JAK3 ANKRD44 ANK3 SMCHD1 PRDM1

1.98e-06192866b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCellmoderate-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIKFYVE FADS3 GRK3 SCN3A BANK1 PXK

1.98e-06192866ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

SFMBT1 JAK3 ANKRD44 ANK3 SMCHD1 PRDM1

2.04e-06193866af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Ptrf|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STARD8 LPL POU3F1 ALDH1A3 SMOC2

6.02e-06133865a1bc34e5dda4ff4716b857931cc196f6770f58f4
ToppCellmild_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

SFMBT1 FADS3 P2RX5 POU3F1 BANK1

8.56e-061438654698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

JAK3 ANKRD44 SMG1 ANK3 SMCHD1

1.57e-05162865b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PIKFYVE ZNF132 P2RX5 NOX4 BANK1

1.57e-05162865ae292318d339305932457bb0e91430594f7a3dfa
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RX5 SCN3A AGBL5 FASTKD3 BANK1

1.97e-0517086532917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

P2RX5 FASTKD3 SHISA4 PROC GPR107

2.03e-051718655636ec11ed1f7aacf98cd9e85853ee1a05bd2cf2
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK4 ANK3 POLI PPIP5K1 POU3F1

2.21e-051748656987fe7959afce347282f632abc16d800ccab7c4
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Cerebellum / BrainAtlas - Mouse McCarroll V32

JAK3 RNASE10 SMOC2 PRDM1

2.24e-0585864bb9555652e93620d5aeeb71e915b3978a437407d
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

JAK3 RNASE10 SMOC2 PRDM1

2.24e-0585864f7935c3206310adafdecb75149c3b06c38e7780c
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

JAK3 RNASE10 SMOC2 PRDM1

2.24e-058586443f6911b032718d8ba75fb7bba5f9b536a4b3260
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

ANKRD44 P2RX5 SMCHD1 BANK1 PRDM1

2.33e-051768659125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

ANKRD44 P2RX5 SMCHD1 SCN3A BANK1

2.40e-05177865653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THAP2 ANK3 MATN2 FRMD8 POU3F2

2.40e-0517786559cf56c385c324f0844f20003d2b5049a2791e45
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIKFYVE P2RX5 SMCHD1 SCN3A BANK1

2.67e-05181865d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Kidney/Urine in Lupus Nephritis

FADS3 GRK3 P2RX5 SCN3A BANK1

2.74e-0518286563c3b63315276b66667d49fab09661ac320e7a36
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 DOCK11 ALDH1A3 SMOC2 HYDIN

2.81e-05183865738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 ST8SIA2 POU3F1 POU3F2

2.81e-051838652cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANKRD44 FADS3 P2RX5 SCN3A BANK1

2.81e-05183865dbc7ec66da5930c2bf4e0405937b054e04c22a34
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 ST8SIA2 POU3F1 POU3F2

2.81e-0518386598fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 POU3F1 SLITRK6 SHISA4

2.81e-051838658330c39184ce076e1f95fd3725b68af551d89db0
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 ST8SIA2 POU3F1 POU3F2 SLITRK6

2.89e-05184865da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 ST8SIA2 POU3F1 SLITRK6

2.89e-05184865a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 SLC39A6 POU3F1 SLITRK6 ALDH1A3

2.96e-05185865ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 OTOGL MATN2 LPL SLITRK6

2.96e-05185865f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell5'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 OTOGL MATN2 LPL SLITRK6

2.96e-05185865317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 OTOGL MATN2 LPL SLITRK6

2.96e-051858657bb8fdfe04f85d25056380ec58222366de323a21
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKRD44 GRK3 DOCK11 SMCHD1 BANK1

2.96e-05185865e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIKFYVE ANKRD44 P2RX5 SMCHD1 BANK1

3.04e-051868651a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIKFYVE ANKRD44 P2RX5 SMCHD1 BANK1

3.04e-05186865f1366638edaecad5cad6367440f4c693513bed7e
ToppCelldroplet-Heart-HEART-1m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 POU3F1 SLITRK6 ALDH1A3

3.04e-05186865fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 MATN2 POU3F1 POU3F2 SLITRK6

3.12e-051878656f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANKRD44 GRK3 P2RX5 SCN3A BANK1

3.12e-05187865160e5f338537d90d50f863a1be801b1071ac7da7
ToppCelldroplet-Heart-HEART-1m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 POU3F1 SLITRK6 ALDH1A3

3.28e-05189865a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF462 DOCK11 ALDH1A3 SMOC2 HYDIN

3.28e-05189865904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 MATN2 POU3F1 SLITRK6 ALDH1A3

3.28e-051898654e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCelllymphoid-B_cell-Naive_B_cell|lymphoid / Lineage, cell class and subclass

PIKFYVE FADS3 GRK3 P2RX5 BANK1

3.36e-05190865b8b05894e811e431d797ac4fa3ccff4963a154e7
ToppCelllymphoid-B_cell|lymphoid / Lineage, cell class and subclass

PIKFYVE FADS3 GRK3 P2RX5 BANK1

3.36e-05190865c451de643ee08c2ff1093e807c65d724237473c5
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

PIKFYVE GRK3 P2RX5 SCN3A BANK1

3.36e-0519086540b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

PIKFYVE GRK3 P2RX5 SCN3A BANK1

3.36e-05190865a37a32dc1b931562a6660074e19d5598efc65284
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANKRD44 GRK3 P2RX5 SMCHD1 BANK1

3.45e-05191865a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

POU3F3 MAB21L2 SLITRK6 SMOC2 SHISA4

3.45e-0519186544b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

SFMBT1 ANKRD44 ANK3 SMCHD1 PRDM1

3.54e-05192865eb4909574fb5fc91399463523e2737095773200a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

JAK3 ANKRD44 SMG1 ANK3 SMCHD1

3.54e-0519286547646d7e4990be85072987f92bf18d52f8da752e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 ALDH1A3 SMOC2 DISP1 PROC

3.62e-051938650f2167eef8203a5659c8c72e4e77646003d64797
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD44 SMG1 ANK3 SMCHD1 ATAD2B

3.62e-051938659337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SFMBT1 JAK3 ANKRD44 SMCHD1 PRDM1

3.62e-051938659c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PIKFYVE ANKRD44 GRK3 P2RX5 BANK1

3.71e-05194865ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ENAM GRK3 P2RX5 SCN3A BANK1

3.71e-051948651b9ec27cdd52a54b55e4ad89162e8a170d57c017
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ENAM PLA2R1 SCN3A ZNF280C BANK1

3.81e-051958651e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

SFMBT1 ANKRD44 ANK3 SMCHD1 PRDM1

3.90e-0519686530e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ANK3 SCN3A POU3F2 MAB21L2 SLITRK6

3.90e-051968650767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD44 SMG1 ANK3 SMCHD1 PRDM1

4.00e-0519786557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellBronchus_Control_(B.)-Immune-TX-B_cells|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PIKFYVE ANKRD44 P2RX5 SMCHD1 BANK1

4.09e-051988656231c44a909dd06f85c8210814e976a5f29148d0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFMBT1 ANKRD44 ANK3 P2RX5 BANK1

4.09e-05198865a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD44 SMG1 ANK3 SMCHD1 ATAD2B

4.19e-05199865f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD44 SMG1 SETD2 SMCHD1 ATAD2B

4.29e-0520086512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZNF462 ANK3 MATN2 SLITRK6 SMOC2

4.29e-0520086509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PIKFYVE P2RX5 SMCHD1 SMOC2 BANK1

4.29e-05200865fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 ANKRD44 ANK3 DOCK11 PRDM1

4.29e-05200865e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCellsevere-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FADS3 P2RX5 SMCHD1 SCN3A BANK1

4.29e-052008650e86f52b6e146d9bbc728d8fb176fc2b53696558
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

GRK3 DOCK11 OTOGL MATN2 LPL

4.29e-05200865bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRK3 P2RX5 SCN3A BANK1

1.21e-04131864a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANKRD44 P2RX5 SMCHD1 BANK1

1.21e-04131864d76a7a9b50ee6d24b74494c6f6b88b3506b3f9ad
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-2|TCGA-Brain / Sample_Type by Project: Shred V9

OTOGL SCN3A SLC39A6 TRUB1

1.52e-041398646f6c64eaa1ce84e0aa9a0caa9c4d9bf7afe626df
ToppCellTransplant_Alveoli_and_parenchyma-Immune-B_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ENAM P2RX5 POU3F1 BANK1

1.79e-0414586434cff6df39ff05995041f0c231c60a50ad1a0c1c
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

P2RX5 ATAD2B BANK1 ZNF687

1.89e-0414786450a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ZNF33A SCN3A ST8SIA2 POU3F2

1.94e-04148864a1269312903fc27830c1835dabf660c659a711be
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FADS3 P2RX5 SCN3A BANK1

2.04e-04150864d9931507257c64ead4a53786e6822f51962c6015
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

SMG1 ANK3 SMCHD1 PRDM1

2.09e-04151864999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FADS3 P2RX5 SCN3A BANK1

2.09e-041518642314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-stem_cells_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

GRK2 ZNF280C NOX4 POU3F1

2.14e-04152864375c9ef88c7703a002e868645a722c35e046ef1e
ToppCellTransplant_Alveoli_and_parenchyma-Immune-B_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

ENAM P2RX5 POU3F1 BANK1

2.14e-0415286466f9190de155251a63a7a669374f342a75d22ea0
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

ANKRD44 SMG1 ANK3 SMCHD1

2.37e-041568641545169694f686d28648a68b552c2ae606599d66
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAM P2RX5 SCN3A BANK1

2.43e-04157864d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF469 P2RX5 SCN3A BANK1

2.49e-0415886441cf950983f47a9e55d56041b301006b42853b37
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GRK2 GRK3 SCN3A BANK1

2.55e-041598642881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell367C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GSTCD PPIP5K1 AGBL5 THAP9

2.67e-041618648de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_naive|bone_marrow / Manually curated celltypes from each tissue

PIKFYVE P2RX5 SMOC2 BANK1

2.73e-0416286444832055b11a789e320c802aadb345e065defc8f
ToppCell3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

P2RX5 NUTM2A POU3F3 BANK1

2.80e-0416386430f5c93c4e170304d701b5231f0d545f404066f7
ToppCellsevere-Lymphocytic-B_cells_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FADS3 P2RX5 SCN3A BANK1

2.86e-04164864a1031e9f945a15186ee14c12be47aa11c3c6583b
ToppCellB_cells-ABCs|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PIKFYVE SCN3A BANK1 E2F8

2.86e-04164864f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENAM ZNF469 P2RX5 ZNF687

2.93e-041658646e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GRK3 P2RX5 SCN3A BANK1

2.93e-04165864fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

GRK3 DOCK11 LPL BANK1

3.00e-041668647e5852891714465c6228c9f955fd511ec79d0e02
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-plasma_cell-plasma_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEK4 REXO2 POLI PRDM1

3.00e-04166864139bf49eb3624d9eec7e8a2cb33d69716d63a7c5
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-plasma_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEK4 REXO2 POLI PRDM1

3.00e-0416686485f59c3cc7db8863ec0044f1fcc14580834f830b
DiseaseEndometrial Stromal Sarcoma

NUTM2B NUTM2A

7.22e-055802C0206630
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

1.08e-046802C0334488
DiseaseRheumatoid Arthritis

GRK2 POU3F1 MAB21L2 PXK PRDM1

1.13e-04174805C0003873
DiseaseAutistic behavior

ZNF462 POU3F3

2.01e-048802C0856975
DiseaseLibman-Sacks Disease

BANK1 PXK PRDM1

5.32e-0458803C0242380
DiseaseManic Disorder

GRK3 ANK3 POU3F2

9.60e-0471803C0024713
DiseaseLupus Erythematosus, Systemic

BANK1 PXK PRDM1

9.60e-0471803C0024141
DiseaseManic

GRK3 ANK3 POU3F2

1.26e-0378803C0338831
DiseaseDepression, Bipolar

GRK3 ANK3 POU3F2

1.31e-0379803C0005587
DiseaseHypertensive disease

GRK2 LPL NOX4 PROC

1.80e-03190804C0020538

Protein segments in the cluster

PeptideGeneStartEntry
KELPTLLHCAAKFGL

BANK1

341

Q8NDB2
SSHKLGSCLLPDSFN

AGBL5

731

Q8NDL9
LGLACDFSKKKPHAS

GRK3

336

P35626
LSYASLKAGSHDPKC

AKAP4

446

Q5JQC9
HESKSGKKFATCNPS

ALDH1A3

41

P47895
KETADCPGHGLLFKT

DUS1L

421

Q6P1R4
CPGHGLLFKTKLEKS

DUS1L

426

Q6P1R4
PKKLQCSAFSHALST

DISP1

1146

Q96F81
LGLACDFSKKKPHAS

GRK2

336

P25098
SCNGPDKLFDSHKLV

PADI1

186

Q9ULC6
HKCLGKELPSDKFTF

GPR107

226

Q5VW38
CHGPITLDFAINKLK

JAK3

376

P52333
HCLKGFTLNPDKKTC

MATN2

386

O00339
KLDSFLPAHLCKRGQ

FRMD8

196

Q9BZ67
LSIFETNCHSGSPKK

ATAD2B

726

Q9ULI0
KLDSFLPAHLCKRGQ

FRMD8P1

196

Q9BZ68
HGKPDKTLRFSLCSD

GAPVD1

556

Q14C86
GKAPAVFVKCHDKSL

LPL

456

P06858
CSLSHNGKDLFKPIQ

PIK3C2A

711

O00443
GLLKSPASLKAHTCK

NEK4

336

P51957
CAGALLKLPFLKAAH

CUL7

1201

Q14999
KGALESHFLKCPKPS

POU3F1

351

Q03052
CKDKKGYTPLHAAAS

ANKRD44

201

Q8N8A2
CCGPNSLSKTLHKLS

NOX4

546

Q9NPH5
LCPLAGNSVHEDKKF

REXO2

136

Q9Y3B8
DSKKKLACGAVLIHP

PROC

231

P04070
DQLLTKPHLGTCHKF

PIKFYVE

796

Q9Y2I7
IPKFCHGILTKAKDD

GLG1

946

Q92896
AKGRSTLPICHFDLK

HYDIN

3941

Q4G0P3
DKNGALKCTFSAPSH

KLHL26

31

Q53HC5
EFLHRKKLFPNGCSA

DOCK11

1651

Q5JSL3
PSRKEKSLGLLCHKF

E2F8

111

A0AVK6
SATLKPVKDLLGCFH

ARFGEF3

1616

Q5TH69
KLCFSRHPTGNSITK

DENND4C

726

Q5VZ89
KALNGFTPLHIACKK

ANK3

396

Q12955
LFQGKPHSALESAAK

MAB21L2

326

Q9Y586
NILHLPCFGSKLAKH

ENAM

1051

Q9NRM1
PSLSHCKLDKRTAGK

CCDC168

4571

Q8NDH2
APLVKSLCAKHGLSY

FADS3

401

Q9Y5Q0
KFQGKGSVSCPLHAS

POLI

551

Q9UNA4
AASKCGIQFLHLPKL

GSTCD

331

Q8NEC7
SVKGALESHFLKCPK

POU3F3

416

P20264
FLSDLKSKLPHICGF

C18orf63

291

Q68DL7
IFKGSLKPDASHTCA

PNLIPRP2

391

P54317
SGLCFKKLNVTTPIH

OTOGL

1596

Q3ZCN5
VKDRSFLKSCHFGPK

P2RX5

211

Q93086
EGQFKSCLKRHTPSL

NUTM2A

16

Q8IVF1
EGQFKSCLKRHTPSL

NUTM2B

16

A6NNL0
EGQFKSCLKRHTPSL

NUTM2E

16

B1AL46
CFTKHKNGLKFPTSL

FAM47E

26

Q6ZV65
TAQPKLIVHCKFSGA

SMCHD1

961

A6NHR9
CTSPGHLDKKELKAL

SLITRK6

546

Q9H5Y7
DGPKRFCSNSKHLLG

FASTKD3

596

Q14CZ7
LFSLPSFHKFCKGLL

SMG1

751

Q96Q15
TSPLKNKHFGTCAIV

ST8SIA2

146

Q92186
KHCLAFSPKTIAGIA

SHISA4

76

Q96DD7
KLHSFLKSFGPPVSC

SPATA31D4

91

Q6ZUB0
SLKVHLKGNCAAAPA

PRDM1

701

O75626
LTSDKKFCSPHQSLL

SCN3A

546

Q9NY46
KGALESHFLKCPKPS

POU3F2

366

P20265
VYKANKTLLPLHCGS

PLA2R1

776

Q13018
CLAPSIFHLNVSKKD

STARD8

721

Q92502
ASGKNKRKALCPDHD

SLC39A6

136

Q13433
HKSNTGFPKLLCASL

CLEC4A

36

Q9UMR7
KLHSFLKSFGPPVSC

SPATA31D3

91

P0C874
CGKAFLKSSTLPNHL

ZNF132

241

P52740
LQKSCHFALSFLIGK

LINC02912

26

Q8N9X5
CGKAFNHPSALTTHK

ZNF714

261

Q96N38
LKGGKCHKSSRPFDL

RNASE10

161

Q5GAN6
KKKNGLHFPSESLCR

THAP9

756

Q9H5L6
LQGCPGAKKHEFLTS

SMOC2

301

Q9H3U7
KGTLRKAKTCDHSAP

PXK

561

Q7Z7A4
ASKACPQTDKFFLHK

SETD2

1121

Q9BYW2
HFPDLSGGKVLSKTC

ZNF469

1486

Q96JG9
KFLCVKSTLSKPHGV

ZNF33A

281

Q06730
ECGKAFNRSPKLTAH

ZNF430

461

Q9H8G1
PFTCKSSLKLGAHKQ

ZNF462

476

Q96JM2
PHKCNKCGKAFISSS

ZNF66

536

Q6ZN08
HCSSLFPAELALKKS

TRUB1

306

Q8WWH5
GKSCDSPLNLKTHFR

ZNF687

1206

Q8N1G0
PGGHSNLACALKKAS

SFMBT1

651

Q9UHJ3
EECGKAFKHPSGLTL

ZNF355P

131

Q9NSJ1
PGKRFCIFKKHSGTL

ZNF280C

666

Q8ND82
RKNFVPGKHTFLCSK

THAP2

41

Q9H0W7
CLISFHSKGFPLDKA

PPIP5K2

96

O43314
HCLISFHSKGFPLDK

PPIP5K1

106

Q6PFW1
ICGKAFFSPSSLKRH

ZNF878

231

C9JN71