Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	AMPA glutamate receptor activity	GRIA3 GRIA4	2.97e-05	4	45	2	GO:0004971
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	2.21e-04	10	45	2	GO:0001849
GeneOntologyMolecularFunction	carbohydrate binding	PLA2R1 C4A C4B LY75 MRC2	6.41e-04	310	45	5	GO:0030246
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIA3 GRIA4	6.61e-04	17	45	2	GO:0004970
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA3 GRIA4	1.33e-03	24	45	2	GO:0099507
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	1.44e-03	25	45	2	GO:0001846
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GRIA3 GRIA4 HTR2A	1.48e-03	100	45	3	GO:0030594
GeneOntologyMolecularFunction	amyloid-beta binding	GRIA3 GRIA4 DLGAP3	1.57e-03	102	45	3	GO:0001540
GeneOntologyMolecularFunction	glutamate receptor activity	GRIA3 GRIA4	1.68e-03	27	45	2	GO:0008066
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	GRIA3 GRIA4 SLC6A19	1.71e-03	105	45	3	GO:0015171
GeneOntologyMolecularFunction	complement binding	C4A C4B	2.36e-03	32	45	2	GO:0001848
GeneOntologyMolecularFunction	dynein intermediate chain binding	SPTBN5 DNAH6	3.15e-03	37	45	2	GO:0045505
GeneOntologyCellularComponent	neuronal cell body	MRGPRX2 GRIA3 GRIA4 DLGAP3 C4A C4B HTR2A DMWD ADAM21	7.22e-05	835	46	9	GO:0043025
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	1.32e-04	8	46	2	GO:0106139
GeneOntologyCellularComponent	cell body	MRGPRX2 GRIA3 GRIA4 DLGAP3 C4A C4B HTR2A DMWD ADAM21	1.63e-04	929	46	9	GO:0044297
GeneOntologyCellularComponent	other organism part	C4A C4B	1.69e-04	9	46	2	GO:0044217
GeneOntologyCellularComponent	somatodendritic compartment	CNTNAP4 MRGPRX2 GRIA3 GRIA4 DLGAP3 C4A C4B HTR2A DMWD ADAM21	2.76e-04	1228	46	10	GO:0036477
GeneOntologyCellularComponent	presynaptic membrane	CNTNAP4 GRIA3 GRIA4 HTR2A OTOF	3.46e-04	277	46	5	GO:0042734
GeneOntologyCellularComponent	dendrite	CNTNAP4 GRIA3 GRIA4 DLGAP3 C4A C4B HTR2A DMWD	5.09e-04	858	46	8	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CNTNAP4 GRIA3 GRIA4 DLGAP3 C4A C4B HTR2A DMWD	5.17e-04	860	46	8	GO:0097447
GeneOntologyCellularComponent	presynaptic active zone membrane	GRIA3 GRIA4 OTOF	6.76e-04	78	46	3	GO:0048787
GeneOntologyCellularComponent	collagen trimer	COL12A1 C1QTNF7 WDR33	9.60e-04	88	46	3	GO:0005581
GeneOntologyCellularComponent	apical part of cell	RHCG SPTBN5 ARHGEF18 LCT OTOF SLC6A19	1.80e-03	592	46	6	GO:0045177
GeneOntologyCellularComponent	AMPA glutamate receptor complex	GRIA3 GRIA4	1.98e-03	30	46	2	GO:0032281
GeneOntologyCellularComponent	axon	MRGPRX2 GRIA3 GRIA4 C4A C4B HTR2A ADAM21	3.13e-03	891	46	7	GO:0030424
GeneOntologyCellularComponent	presynaptic active zone	GRIA3 GRIA4 OTOF	3.69e-03	141	46	3	GO:0048786
GeneOntologyCellularComponent	ionotropic glutamate receptor complex	GRIA3 GRIA4	4.42e-03	45	46	2	GO:0008328
Domain	FN_type2_col-bd	PLA2R1 LY75 MRC2	4.99e-06	14	46	3	IPR000562
Domain	FN2_2	PLA2R1 LY75 MRC2	4.99e-06	14	46	3	PS51092
Domain	fn2	PLA2R1 LY75 MRC2	4.99e-06	14	46	3	PF00040
Domain	FN2_1	PLA2R1 LY75 MRC2	4.99e-06	14	46	3	PS00023
Domain	FN2	PLA2R1 LY75 MRC2	4.99e-06	14	46	3	SM00059
Domain	RICIN	PLA2R1 LY75 MRC2	4.39e-05	28	46	3	SM00458
Domain	RICIN_B_LECTIN	PLA2R1 LY75 MRC2	4.39e-05	28	46	3	PS50231
Domain	Ricin_B_lectin	PLA2R1 LY75 MRC2	5.42e-05	30	46	3	IPR000772
Domain	Anaphylatoxin_comp_syst	C4A C4B	5.91e-05	5	46	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	5.91e-05	5	46	2	IPR001840
Domain	Kringle-like	PLA2R1 LY75 MRC2	6.60e-05	32	46	3	IPR013806
Domain	ANATO	C4A C4B	1.24e-04	7	46	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	1.24e-04	7	46	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.24e-04	7	46	2	PS01177
Domain	ANATO	C4A C4B	1.24e-04	7	46	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	1.24e-04	7	46	2	IPR000020
Domain	C-type_lectin_CS	PLA2R1 LY75 MRC2	1.61e-04	43	46	3	IPR018378
Domain	MacrogloblnA2_CS	C4A C4B	1.65e-04	8	46	2	IPR019742
Domain	Thiol-ester_cl	C4A C4B	1.65e-04	8	46	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	1.65e-04	8	46	2	IPR019565
Domain	A2M_N	C4A C4B	2.64e-04	10	46	2	PF01835
Domain	A2M_N_2	C4A C4B	2.64e-04	10	46	2	PF07703
Domain	A2M_N	C4A C4B	2.64e-04	10	46	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	2.64e-04	10	46	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	2.64e-04	10	46	2	PS00477
Domain	A2M_recep	C4A C4B	2.64e-04	10	46	2	PF07677
Domain	A2M_comp	C4A C4B	2.64e-04	10	46	2	PF07678
Domain	A2M	C4A C4B	2.64e-04	10	46	2	PF00207
Domain	A2M_N_2	C4A C4B	2.64e-04	10	46	2	IPR011625
Domain	A2M_comp	C4A C4B	2.64e-04	10	46	2	IPR011626
Domain	Macroglobln_a2	C4A C4B	2.64e-04	10	46	2	IPR001599
Domain	WD40	WDR55 FBXW10B FBXW10 DMWD WDR33	4.25e-04	259	46	5	PF00400
Domain	-	PLA2R1 MRC2	4.55e-04	13	46	2	2.10.10.10
Domain	WD40	WDR55 FBXW10B FBXW10 DMWD WDR33	4.97e-04	268	46	5	SM00320
Domain	WD40_repeat	WDR55 FBXW10B FBXW10 DMWD WDR33	5.31e-04	272	46	5	IPR001680
Domain	WD_REPEATS_1	WDR55 FBXW10B FBXW10 DMWD WDR33	5.87e-04	278	46	5	PS00678
Domain	WD_REPEATS_2	WDR55 FBXW10B FBXW10 DMWD WDR33	5.96e-04	279	46	5	PS50082
Domain	WD_REPEATS_REGION	WDR55 FBXW10B FBXW10 DMWD WDR33	5.96e-04	279	46	5	PS50294
Domain	C345C	C4A C4B	7.88e-04	17	46	2	SM00643
Domain	WD40_repeat_dom	WDR55 FBXW10B FBXW10 DMWD WDR33	7.90e-04	297	46	5	IPR017986
Domain	Iontro_rcpt	GRIA3 GRIA4	8.85e-04	18	46	2	IPR001320
Domain	Lig_chan	GRIA3 GRIA4	8.85e-04	18	46	2	PF00060
Domain	Lig_chan-Glu_bd	GRIA3 GRIA4	8.85e-04	18	46	2	PF10613
Domain	PBPe	GRIA3 GRIA4	8.85e-04	18	46	2	SM00079
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	8.85e-04	18	46	2	IPR008930
Domain	Iono_rcpt_met	GRIA3 GRIA4	8.85e-04	18	46	2	IPR001508
Domain	Glu/Gly-bd	GRIA3 GRIA4	8.85e-04	18	46	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIA3 GRIA4	8.85e-04	18	46	2	SM00918
Domain	NTR	C4A C4B	9.88e-04	19	46	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	9.88e-04	19	46	2	IPR018933
Domain	C_TYPE_LECTIN_1	PLA2R1 LY75 MRC2	1.01e-03	80	46	3	PS00615
Domain	Lectin_C	PLA2R1 LY75 MRC2	1.16e-03	84	46	3	PF00059
Domain	CLECT	PLA2R1 LY75 MRC2	1.16e-03	84	46	3	SM00034
Domain	Collagen	COL12A1 C1QTNF7 WDR33	1.20e-03	85	46	3	PF01391
Domain	Collagen	COL12A1 C1QTNF7 WDR33	1.20e-03	85	46	3	IPR008160
Domain	C_TYPE_LECTIN_2	PLA2R1 LY75 MRC2	1.20e-03	85	46	3	PS50041
Domain	MHC_I	ULBP2 AZGP1	1.21e-03	21	46	2	PF00129
Domain	MHC_I_a_a1/a2	ULBP2 AZGP1	1.21e-03	21	46	2	IPR001039
Domain	C-type_lectin-like	PLA2R1 LY75 MRC2	1.24e-03	86	46	3	IPR001304
Domain	-	WDR55 FBXW10B FBXW10 DMWD WDR33	1.32e-03	333	46	5	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR55 FBXW10B FBXW10 DMWD WDR33	1.35e-03	335	46	5	IPR015943
Domain	Netrin_domain	C4A C4B	1.45e-03	23	46	2	IPR001134
Domain	NTR	C4A C4B	1.45e-03	23	46	2	PS50189
Domain	-	ULBP2 AZGP1	1.58e-03	24	46	2	3.30.500.10
Domain	MHC_I-like_Ag-recog	ULBP2 AZGP1	1.58e-03	24	46	2	IPR011161
Domain	-	CNTNAP4 COL12A1 ADGRD1	1.65e-03	95	46	3	2.60.120.200
Domain	TIMP-like_OB-fold	C4A C4B	1.86e-03	26	46	2	IPR008993
Domain	C-type_lectin-like/link	PLA2R1 LY75 MRC2	1.86e-03	99	46	3	IPR016186
Domain	CTDL_fold	PLA2R1 LY75 MRC2	2.32e-03	107	46	3	IPR016187
Domain	ANF_receptor	GRIA3 GRIA4	3.74e-03	37	46	2	PF01094
Domain	ANF_lig-bd_rcpt	GRIA3 GRIA4	3.74e-03	37	46	2	IPR001828
Domain	MHC_I/II-like_Ag-recog	ULBP2 AZGP1	3.94e-03	38	46	2	IPR011162
Domain	Peripla_BP_I	GRIA3 GRIA4	4.15e-03	39	46	2	IPR028082
Domain	AAA+_ATPase	DNAH6 ATAD5 RAD17	5.35e-03	144	46	3	IPR003593
Domain	AAA	DNAH6 ATAD5 RAD17	5.35e-03	144	46	3	SM00382
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	1.47e-04	7	38	2	MM14685
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	1.96e-04	8	38	2	M47872
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	1.96e-04	8	38	2	M27031
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	3.83e-04	11	38	2	M47874
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	3.83e-04	11	38	2	MM1430
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	4.59e-04	12	38	2	MM1368
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	5.42e-04	13	38	2	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	7.27e-04	15	38	2	M7146
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	GRIA3 GRIA4 DLGAP3	7.69e-04	67	38	3	MM15327
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA3 GRIA4	8.29e-04	16	38	2	MM15048
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	9.38e-04	17	38	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	9.38e-04	17	38	2	MM1369
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA3 GRIA4	9.38e-04	17	38	2	M5488
Pathway	WP_NRXN1_DELETION_SYNDROME	GRIA3 GRIA4	1.05e-03	18	38	2	M48098
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	RHCG SLC22A15 SLC6A19	1.11e-03	76	38	3	MM15072
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.30e-03	20	38	2	M917
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA3 GRIA4	1.30e-03	20	38	2	MM15485
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA3 GRIA4	1.44e-03	21	38	2	M27736
Pathway	REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION	GRIA3 GRIA4	1.44e-03	21	38	2	M838
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	RHCG SLC22A15 SLC6A19	1.48e-03	84	38	3	M27334
Pathway	WP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA	GRIA3 GRIA4	1.58e-03	22	38	2	M39795
Pathway	REACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION	GRIA3 GRIA4	1.58e-03	22	38	2	MM15104
Pathway	WP_COMPLEMENT_ACTIVATION	C4A C4B	1.58e-03	22	38	2	M39502
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	GRIA3 GRIA4 DLGAP3	1.64e-03	87	38	3	M27617
Pathway	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	GRIA3 GRIA4	2.74e-03	29	38	2	MM15028
Pathway	WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY	C4A C4B CSMD1	2.88e-03	106	38	3	M42535
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	CNTNAP4 GRIA3 GRIA4 DLGAP3 HTR2A	2.88e-03	367	38	5	M48346
Pathway	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	GRIA3 GRIA4	3.13e-03	31	38	2	M7223
Pathway	REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS	GRIA3 GRIA4	3.98e-03	35	38	2	MM15109
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.71e-06	2	46	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.71e-06	2	46	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.71e-06	2	46	2	15998580
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.71e-06	2	46	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	1.71e-06	2	46	2	17728371
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	1.71e-06	2	46	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.71e-06	2	46	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	1.71e-06	2	46	2	3696167
Pubmed	Structure and organization of the C4 genes.	C4A C4B	1.71e-06	2	46	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	1.71e-06	2	46	2	6149581
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	1.71e-06	2	46	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	1.71e-06	2	46	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.71e-06	2	46	2	19933335
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	1.71e-06	2	46	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	1.71e-06	2	46	2	3542363
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	1.71e-06	2	46	2	37450367
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	1.71e-06	2	46	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	1.71e-06	2	46	2	8132550
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.71e-06	2	46	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.71e-06	2	46	2	17645767
Pubmed	Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.	GRIA3 GRIA4	1.71e-06	2	46	2	12670305
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	1.71e-06	2	46	2	15787745
Pubmed	Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.	GRIA3 GRIA4	1.71e-06	2	46	2	18316356
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.71e-06	2	46	2	12207352
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	1.71e-06	2	46	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	1.71e-06	2	46	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	1.71e-06	2	46	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	1.71e-06	2	46	2	6167582
Pubmed	Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.	GRIA3 GRIA4	1.71e-06	2	46	2	7992055
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	1.71e-06	2	46	2	16908004
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	1.71e-06	2	46	2	30026462
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	1.71e-06	2	46	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	1.71e-06	2	46	2	7365238
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	1.71e-06	2	46	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.71e-06	2	46	2	27758680
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	1.71e-06	2	46	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	1.71e-06	2	46	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	1.71e-06	2	46	2	17506029
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.71e-06	2	46	2	22387014
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	1.71e-06	2	46	2	17971360
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	1.71e-06	2	46	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	1.71e-06	2	46	2	20506482
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	1.71e-06	2	46	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	1.71e-06	2	46	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	1.71e-06	2	46	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	1.71e-06	2	46	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	1.71e-06	2	46	2	17971229
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	1.71e-06	2	46	2	12480675
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	1.71e-06	2	46	2	6881182
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	1.71e-06	2	46	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.71e-06	2	46	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.71e-06	2	46	2	23918728
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	1.71e-06	2	46	2	3944109
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	1.71e-06	2	46	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.71e-06	2	46	2	3037333
Pubmed	Elimination of redundant synaptic inputs in the absence of synaptic strengthening.	GRIA3 GRIA4	1.71e-06	2	46	2	22090494
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.71e-06	2	46	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.71e-06	2	46	2	4216347
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	1.71e-06	2	46	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	1.71e-06	2	46	2	21880985
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	1.71e-06	2	46	2	1699796
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	1.71e-06	2	46	2	6978711
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.71e-06	2	46	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	1.71e-06	2	46	2	2997024
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	1.71e-06	2	46	2	35898513
Pubmed	Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.	C4A C4B	1.71e-06	2	46	2	33353966
Pubmed	Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp).	C4A C4B	1.71e-06	2	46	2	3008092
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.71e-06	2	46	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	1.71e-06	2	46	2	3624865
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	1.71e-06	2	46	2	28873507
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	1.71e-06	2	46	2	31400758
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.71e-06	2	46	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	1.71e-06	2	46	2	21857912
Pubmed	The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.	C4A C4B	1.71e-06	2	46	2	6609966
Pubmed	Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.	C4A C4B	1.71e-06	2	46	2	2900855
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.71e-06	2	46	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	1.71e-06	2	46	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	1.71e-06	2	46	2	4514997
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	1.71e-06	2	46	2	276882
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.71e-06	2	46	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	1.71e-06	2	46	2	5919331
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	1.71e-06	2	46	2	6832377
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	1.71e-06	2	46	2	3167981
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	1.71e-06	2	46	2	3794341
Pubmed	Complement and c4 null alleles in severe chronic adult periodontitis.	C4A C4B	1.71e-06	2	46	2	17257223
Pubmed	Three extra copies of a C4-related gene in H-2w7 mice are C4/Slp hybrid genes generated by multiple recombinational events.	C4A C4B	1.71e-06	2	46	2	2272665
Pubmed	Multiple C4/Slp genes distinguished by expression after transfection.	C4A C4B	1.71e-06	2	46	2	3023818
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	1.71e-06	2	46	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	1.71e-06	2	46	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.71e-06	2	46	2	2572548
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	1.71e-06	2	46	2	22785613
Pubmed	The complement component C4 of mammals.	C4A C4B	1.71e-06	2	46	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	1.71e-06	2	46	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	1.71e-06	2	46	2	34358307
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	1.71e-06	2	46	2	32691186
Pubmed	Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.	C4A C4B	1.71e-06	2	46	2	23259761
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	1.71e-06	2	46	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.71e-06	2	46	2	22151770
Pubmed	GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.	GRIA3 GRIA4	1.71e-06	2	46	2	21690196
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.71e-06	2	46	2	18091514
Interaction	FBXW10B interactions	FBXW10B FBXW10	1.53e-05	3	46	2	int:FBXW10B
Cytoband	17p12	FBXW10B FBXW10	1.12e-03	49	46	2	17p12
GeneFamily	Glutamate ionotropic receptor AMPA type subunits	GRIA3 GRIA4	2.18e-05	4	35	2	1200
GeneFamily	C-type lectin domain family	PLA2R1 LY75 MRC2	1.02e-04	47	35	3	494
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.30e-04	9	35	2	1234
GeneFamily	WD repeat domain containing	WDR55 FBXW10B FBXW10 DMWD WDR33	1.40e-04	262	35	5	362
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	1.98e-04	11	35	2	559
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	2.20e-03	36	35	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	2.32e-03	37	35	2	454
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 C1QTNF7 CSMD1 MRC2 ADGRD1	1.60e-06	192	46	5	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 CSMD1 MRC2 ADGRD1	1.60e-06	192	46	5	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 C1QTNF7 CSMD1 MRC2 ADGRD1	1.60e-06	192	46	5	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 C1QTNF7 CSMD1 MRC2 ADGRD1	1.60e-06	192	46	5	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 CSMD1 MRC2 ADGRD1	1.60e-06	192	46	5	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CLINT1 ADAM21 NACAD SLC6A19	1.36e-05	141	46	4	7ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DLGAP3 TLK1 DNAH6 MRC2	2.46e-05	164	46	4	346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 HTR2A DNAH6 ADGRD1	3.47e-05	179	46	4	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	C1QTNF7 CSMD1 BCOR SLC6A19	3.62e-05	181	46	4	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 HTR2A DNAH6 ADGRD1	3.86e-05	184	46	4	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 C4B C1QTNF7 ADGRD1	3.95e-05	185	46	4	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 C4B C1QTNF7 ADGRD1	3.95e-05	185	46	4	049d793d043d5d434f143025de49dd210d18756c
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 C4B C1QTNF7 ADGRD1	3.95e-05	185	46	4	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 DLGAP3 CSMD1 OTOF	4.03e-05	186	46	4	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1210 COL12A1 MRC2 ADGRD1	4.20e-05	188	46	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP4 PLA2R1 GRIA4 C1QTNF7	4.20e-05	188	46	4	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B CSMD1 MRC2 ADGRD1	4.29e-05	189	46	4	544d95df910f1b276995624509a7e41b219baca0
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 C1QTNF7 DNAH6 ADGRD1	4.29e-05	189	46	4	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 C1QTNF7 DNAH6 ADGRD1	4.29e-05	189	46	4	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 C1QTNF7 DNAH6 ADGRD1	4.29e-05	189	46	4	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 C4B C1QTNF7 MRC2	4.38e-05	190	46	4	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 C4B C1QTNF7 MRC2	4.38e-05	190	46	4	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2R1 C4B C1QTNF7 MRC2	4.47e-05	191	46	4	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C4B C1QTNF7 MRC2 ADGRD1	4.47e-05	191	46	4	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLA2R1 C4B C1QTNF7 MRC2	4.47e-05	191	46	4	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.56e-05	192	46	4	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C4B C1QTNF7 MRC2 ADGRD1	4.56e-05	192	46	4	c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.56e-05	192	46	4	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C4B C1QTNF7 MRC2 ADGRD1	4.56e-05	192	46	4	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.56e-05	192	46	4	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 DLGAP3 CSMD1 OTOF	4.65e-05	193	46	4	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIA3 C4B C1QTNF7 MRC2	4.65e-05	193	46	4	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 DLGAP3 CSMD1 OTOF	4.65e-05	193	46	4	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.65e-05	193	46	4	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 DLGAP3 CSMD1 OTOF	4.65e-05	193	46	4	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1210 COL12A1 MRC2 ADGRD1	4.65e-05	193	46	4	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.65e-05	193	46	4	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIA3 C4B C1QTNF7 MRC2	4.65e-05	193	46	4	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 COL12A1 MRC2 ADGRD1	4.75e-05	194	46	4	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B C1QTNF7 MRC2 ADGRD1	4.75e-05	194	46	4	2d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RHCG KIAA1210 GRIA4 ATAD5	4.75e-05	194	46	4	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 COL12A1 MRC2 ADGRD1	4.75e-05	194	46	4	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 C1QTNF7 HTR2A CSMD1	4.84e-05	195	46	4	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 COL12A1 C1QTNF7 MRC2	4.84e-05	195	46	4	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 C1QTNF7 HTR2A CSMD1	4.84e-05	195	46	4	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 COL12A1 MRC2 ADGRD1	4.84e-05	195	46	4	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C4B C1QTNF7 MRC2 ADGRD1	4.94e-05	196	46	4	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 C1QTNF7 MRC2 ADGRD1	5.34e-05	200	46	4	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL12A1 HTR2A DNAH6 ADGRD1	5.34e-05	200	46	4	1a3d29a580d1b405a74869a1da3e818c581fc559
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E---L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL12A1 HTR2A DNAH6 ADGRD1	5.34e-05	200	46	4	6f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL12A1 ADAM21 MRC2 ADGRD1	5.34e-05	200	46	4	3e0041c04e42a47257517dae8707a6454570c256
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL12A1 HTR2A DNAH6 ADGRD1	5.34e-05	200	46	4	86705dfc05b3e1576543b93883c88fb55b742855
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL12A1 HTR2A DNAH6 ADGRD1	5.34e-05	200	46	4	db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHCG C4A C4B	1.30e-04	95	46	3	a09443e527d37adb637a66ca857525dab1c39a9b
ToppCell	Control-CD4+_T_activated\|Control / Disease condition and Cell class	FBXW10B PLA2R1 MRC2	2.34e-04	116	46	3	e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FBXW10B PLA2R1 MRC2	2.46e-04	118	46	3	f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBXW10B PLA2R1 MRC2	2.46e-04	118	46	3	0dcac16eea8e7978de370a815da9a0cdd212598e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBXW10B PLA2R1 MRC2	2.46e-04	118	46	3	7da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FBXW10B PLA2R1 MRC2	2.46e-04	118	46	3	c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCell	Control-Lymphoid_T/NK-CD4+_T_activated\|Control / Disease group, lineage and cell class	FBXW10B PLA2R1 MRC2	2.52e-04	119	46	3	d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHCG C4A C4B	2.78e-04	123	46	3	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-2\|TCGA-Bladder / Sample_Type by Project: Shred V9	C4A HTR2A ADGRD1	2.84e-04	124	46	3	ff08f74c3bc8e60679e0e21370095936a174c580
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RHCG GRIA3 ADGRD1	3.57e-04	134	46	3	0b1bb6fee8a2d8c27bca6d9cac6b47e85073dbf7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RHCG C4A SLC22A15	3.81e-04	137	46	3	85b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RHCG LY75 OTOF	4.14e-04	141	46	3	9a0f4bee2893da1b13ab89494e6159821d53538b
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL12A1 MRC2 DDX4	4.23e-04	142	46	3	671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL12A1 MRC2 DDX4	4.23e-04	142	46	3	3557084150670fd2e2634fc674f228ab85181b59
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL12A1 MRC2 DDX4	4.23e-04	142	46	3	6a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL12A1 MRC2 DDX4	4.23e-04	142	46	3	a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLGAP3 CLINT1 AZGP1	4.41e-04	144	46	3	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Thalamus / BrainAtlas - Mouse McCarroll V32	HTR2A OTOF DDX4	4.77e-04	148	46	3	afebb64365c94b9476494bffe7c364677f19c8cf
ToppCell	Thalamus-Neuronal-Inhibitory\|Thalamus / BrainAtlas - Mouse McCarroll V32	HTR2A OTOF DDX4	4.77e-04	148	46	3	5f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL12A1 C1QTNF7 MRC2	4.87e-04	149	46	3	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	GRIA3 MRC2 ADGRD1	4.87e-04	149	46	3	d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	PLA2R1 COL12A1 MRC2	5.06e-04	151	46	3	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIA4 BCOR ATAD5	5.88e-04	159	46	3	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTNAP4 GRIA4 COL12A1	5.99e-04	160	46	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTNAP4 GRIA4 COL12A1	5.99e-04	160	46	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 NACAD SLC6A19	5.99e-04	160	46	3	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CNTNAP4 GRIA4 HTR2A	6.10e-04	161	46	3	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIA4 CSMD1 ADGRD1	6.21e-04	162	46	3	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	Bronchial-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DMWD AZGP1 SLC22A15	6.21e-04	162	46	3	afffecc6c504930554aafc12c5bffa53e3c5b016
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIA4 CSMD1 ADGRD1	6.21e-04	162	46	3	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIA4 CSMD1 ADGRD1	6.21e-04	162	46	3	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDH26 CSMD1 AZGP1	6.21e-04	162	46	3	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	Frontal_cortex\|World / BrainAtlas - Mouse McCarroll V32	GRIA3 COL12A1 HTR2A	6.43e-04	164	46	3	e09291711abf8680e78170328313719092b0142f
ToppCell	Ionocyte\|World / shred by cell class for turbinate	DLGAP3 DDX4 AZGP1	6.55e-04	165	46	3	0cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4B ADGRD1 SLC22A15	6.55e-04	165	46	3	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	wk_20-22-Hematologic-Myeloid-GMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FAM149B1 RTTN SLC22A15	6.66e-04	166	46	3	d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN5 DLGAP3 ATAD5	6.78e-04	167	46	3	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	droplet-Lung-LUNG-1m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LY75 ATAD5 DDX4	6.78e-04	167	46	3	e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCell	Tuft-tuft-1\|World / Class top	C4B AZGP1 RTTN	6.90e-04	168	46	3	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABHD3 LY75 RTTN	6.90e-04	168	46	3	a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C4A C4B C1QTNF7	6.90e-04	168	46	3	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA4 C4B DNAH6	7.02e-04	169	46	3	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2R1 GRIA4 MRC2	7.02e-04	169	46	3	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHCG LY75 SLC22A15	7.26e-04	171	46	3	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHCG LY75 SLC22A15	7.26e-04	171	46	3	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SPTBN5 ULBP2 OTOF	7.26e-04	171	46	3	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBXW10B COL12A1 CSMD1	7.26e-04	171	46	3	121e63ca281ad765d76c2afb3b4d441329b47f81
Drug	anisamide	GRIA3 HTR2A LCT	1.16e-05	22	46	3	CID000075540
Drug	CX516	GRIA3 GRIA4 HTR2A	1.16e-05	22	46	3	CID000148184
Drug	2-aminothiophenol	C4A C4B	1.20e-05	3	46	2	ctd:C005464
Drug	3-pyridazinol 1-oxide	GRIA3 GRIA4	2.39e-05	4	46	2	CID000574311
Drug	Aniracetam	GRIA3 HTR2A	2.39e-05	4	46	2	DB04599
Drug	KW-6002	GRIA3 GRIA4 HTR2A	3.67e-05	32	46	3	CID005311037
Drug	AC1L1YEG	GRIA3 GRIA4	3.98e-05	5	46	2	CID000063114
Drug	Chicago acid	GRIA3 GRIA4	3.98e-05	5	46	2	CID000065740
Drug	CHEBI:570577	GRIA3 GRIA4	3.98e-05	5	46	2	CID011334126
Drug	1-BCP	GRIA3 GRIA4	3.98e-05	5	46	2	CID000001370
Drug	irampanel	GRIA3 GRIA4	3.98e-05	5	46	2	CID003038472
Drug	beta-N-oxalylaminoalanine	GRIA3 GRIA4	3.98e-05	5	46	2	CID000107978
Drug	LY395153	GRIA3 GRIA4	3.98e-05	5	46	2	CID000656707
Drug	5-h PCA	GRIA3 GRIA4	3.98e-05	5	46	2	CID000129091
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	SPTBN5 GRIA3 DMWD NACAD MRC2	4.74e-05	197	46	5	4566_UP
Drug	(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; PC3; HT_HG-U133A	SPTBN5 GRIA3 ZBTB7A HTR2A DMWD	4.97e-05	199	46	5	4259_UP
Drug	2cmo	GRIA3 GRIA4	5.96e-05	6	46	2	CID006914597
Drug	YM928	GRIA3 GRIA4	5.96e-05	6	46	2	CID006918393
Drug	thio-ATPA	GRIA3 GRIA4	8.33e-05	7	46	2	CID005289517
Drug	4,6-dichloroindole-2-carboxylic acid	GRIA3 GRIA4	8.33e-05	7	46	2	CID000127988
Drug	LY341495	GRIA3 GRIA4 HTR2A	9.00e-05	43	46	3	CID006324636
Drug	olanzapine	GRIA3 C4A C4B HTR2A	1.04e-04	121	46	4	ctd:C076029
Drug	2,3-PDCA	GRIA3 GRIA4	1.11e-04	8	46	2	CID000127037
Drug	homoibotenic acid	GRIA3 GRIA4	1.11e-04	8	46	2	CID000194385
Drug	1-hydroxypyrazole	GRIA3 GRIA4	1.11e-04	8	46	2	CID003016733
Drug	1-hydroxyimidazole	GRIA3 GRIA4	1.11e-04	8	46	2	CID003614351
Drug	Ly294486	GRIA3 GRIA4	1.42e-04	9	46	2	CID005311255
Drug	1m5b	GRIA3 GRIA4	1.42e-04	9	46	2	CID000447081
Drug	isothiazol-3-one	GRIA3 GRIA4	1.42e-04	9	46	2	CID000096917
Drug	M100907	GRIA3 GRIA4 HTR2A	1.50e-04	51	46	3	CID000060858
Drug	LY354740	GRIA3 GRIA4 HTR2A	1.50e-04	51	46	3	CID000114827
Drug	AC1O4QI2	GRIA3 GRIA4 C4A LY75	1.68e-04	137	46	4	CID006398444
Drug	AC1LCY75	C4A LCT	1.78e-04	10	46	2	CID000639298
Drug	Benzoates	GRIA3 GRIA4	1.78e-04	10	46	2	ctd:D001565
Drug	MDL 28170	SPTBN5 GRIA3 GRIA4	1.78e-04	54	46	3	CID000072430
Drug	tetrahydroisoquinoline	GRIA3 GRIA4 HTR2A	1.98e-04	56	46	3	CID000007046
Drug	0-ol	GRIA3 GRIA4	2.17e-04	11	46	2	CID000069892
Drug	J-ST	GRIA3 GRIA4	2.17e-04	11	46	2	CID005288655
Drug	sym 2206	GRIA3 GRIA4	2.17e-04	11	46	2	CID005039877
Drug	YM872	GRIA3 GRIA4	2.17e-04	11	46	2	CID000148200
Drug	C-X6	GRIA3 GRIA4	2.60e-04	12	46	2	CID005288002
Drug	Atpa	GRIA3 GRIA4	2.60e-04	12	46	2	CID000002252
Drug	1NaPP1	GRIA3 GRIA4	2.60e-04	12	46	2	CID000004877
Drug	Naspm	GRIA3 GRIA4	3.07e-04	13	46	2	CID000129695
Disease	secretory phospholipase A2 receptor measurement	PLA2R1 LY75	7.13e-06	3	46	2	EFO_0802043
Disease	glucagon-like peptide-1 measurement	COL12A1 CSMD1	1.06e-04	10	46	2	EFO_0008465
Disease	triacylglycerol 52:1 measurement	CSMD1 SLC22A15	2.14e-04	14	46	2	EFO_0010413
Disease	central nervous system disease (implicated_via_orthology)	GRIA3 GRIA4	2.81e-04	16	46	2	DOID:331 (implicated_via_orthology)
Disease	triacylglycerol 46:1 measurement	CSMD1 SLC22A15	4.44e-04	20	46	2	EFO_0010401
Disease	triacylglycerol 48:2 measurement	CSMD1 SLC22A15	5.38e-04	22	46	2	EFO_0010405
Disease	triacylglycerol 48:3 measurement	CSMD1 SLC22A15	5.38e-04	22	46	2	EFO_0010406
Disease	alpha-linolenic acid measurement	CSMD1 LCT	6.97e-04	25	46	2	EFO_0007759
Disease	Drug Use Disorders	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0013222
Disease	Drug Dependence	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C1510472
Disease	Drug habituation	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0013170
Disease	Substance Dependence	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0038580
Disease	Substance Use Disorders	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0038586
Disease	Substance-Related Disorders	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0236969
Disease	Drug abuse	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0013146
Disease	Organic Mental Disorders, Substance-Induced	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C0029231
Disease	Prescription Drug Abuse	PLA2R1 GRIA4 CSMD1	7.75e-04	115	46	3	C4316881
Disease	Substance abuse problem	PLA2R1 GRIA4 CSMD1	7.94e-04	116	46	3	C0740858
Disease	triacylglycerol 50:2 measurement	CSMD1 SLC22A15	1.07e-03	31	46	2	EFO_0010409
Disease	joint hypermobility measurement	COL12A1 C1QTNF7	1.22e-03	33	46	2	EFO_0007905
Disease	Complement deficiency disease	C4A C4B	1.22e-03	33	46	2	C0272242
Disease	Graves' disease (is_implicated_in)	C4A C4B	1.70e-03	39	46	2	DOID:12361 (is_implicated_in)
Disease	triacylglycerol 50:3 measurement	CSMD1 SLC22A15	1.70e-03	39	46	2	EFO_0010410
Disease	systemic lupus erythematosus (implicated_via_orthology)	C4A C4B	2.06e-03	43	46	2	DOID:9074 (implicated_via_orthology)
Disease	heart rate variability measurement, response to antipsychotic drug	COL12A1 CSMD1	2.36e-03	46	46	2	EFO_0008003, GO_0097332
Disease	health literacy measurement	TLK1 CSMD1	3.11e-03	53	46	2	EFO_0010104

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGLCDEFSLESNDGW	ATAD5	1686	Q96QE3
SNLTWFEFLSESEDG	ARHGEF18	231	Q6ZSZ5
WLEFNTNGSDTDQGF	CSMD1	1191	Q96PZ7
FSNSRFEDGDSSGFW	DDX4	96	Q9NQI0
VFQAAGLAFSDGDQW	C4B	646	P0C0L5
AFLDFSSGEGVWSNH	ADGRD1	511	Q6QNK2
DCGVDNFQGDTWSLF	ADAM21	321	Q9UKJ8
FFDQWHLLSGSTDGL	FBXW10	581	Q5XX13
DFNSGEANTSDAFNW	HTR2A	31	P28223
EDSIWGFSGNANADS	CNTNAP4	126	Q9C0A0
DGGQISLDWFDNDNS	ABHD3	116	Q8WU67
LQGRNDDDASGTWDF	BCOR	1586	Q6W2J9
FGSAGQDTQFCLWDL	DMWD	431	Q09019
SEFLSFADILSGDWN	RAD17	471	O75943
FFDQWHLLSGSTDGL	FBXW10B	581	O95170
TSGNGDFGDWSAFNQ	CLINT1	366	Q14677
NEFGIFNSLWFSLGA	GRIA3	601	P42263
NEFGIFNSLWFSLGA	GRIA4	591	P48058
DNFEWATGFSERFGL	LCT	1796	P09848
LWIGLFSQDDELNFG	LY75	1161	O60449
FSQDDELNFGWSDGK	LY75	1166	O60449
DLNSTGSFFWLSGDE	MRC2	586	Q9UBG0
SDAEWNFFLRGSAGL	DNAH6	3386	Q9C0G6
FLTDASWSIGDDNFN	COL12A1	2326	Q99715
WSSDDNLDSDSGFLA	DLGAP3	261	O95886
SDPFTFELDNTWGNA	CDH26	531	Q8IXH8
SNSDNWFLGRDEAFA	KIAA1210	1391	Q9ULL0
GGDFDFFSNLVTKWE	SDR39U1	126	Q9NRG7
AGEDQAFGDWLLTAN	SLC22A15	66	Q8IZD6
FTDQNGLFSDPGWAD	C1QTNF7	251	Q9BXJ2
VFQAAGLAFSDGDQW	C4A	646	P0C0L4
GSWDDGDFLGDESLQ	OTOF	126	Q9HC10
SSDFSWGYGELDQNA	FAM149B1	86	Q96BN6
ESNDLNGLDDSFKFW	RTTN	1516	Q86VV8
DTWLDAGAQVFFSFS	SLC6A19	266	Q695T7
WGLNSLFTDLLNFDD	UBE2F	141	Q969M7
LFSDGDSGWCQTFDF	MRGPRX2	171	Q96LB1
LFTTDNGLNFDWSDG	PLA2R1	1176	Q13018
NGLNFDWSDGTKSSF	PLA2R1	1181	Q13018
DFSRSWSDGLGFNAL	SPTBN5	201	Q9NRC6
SFTEQWTDGFAFQNL	TLK1	311	Q9UKI8
FDFQGFNGDWTARTQ	RHCG	376	Q9UBD6
FGCEIENNRSSGAFW	AZGP1	121	P25311
LFNWNGFGATSDRFA	WDR55	236	Q9H6Y2
GEFTLWNGLTFNFET	WDR33	141	Q9C0J8
SGSWQFSFDGQIFLL	ULBP2	136	Q9BZM5
ASFPWSAFGASDDDL	ZBTB7A	181	O95365
SSWGQEGHFFDLDFL	NACAD	286	O15069