Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

PGA4 PGA5 PGC PGA3

1.81e-0537854GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

PGA4 PGA5 PGC PGA3

2.02e-0538854GO:0070001
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA2D1 CACNA2D2 CACNA1I GRM7

4.35e-0546854GO:0005245
GeneOntologyMolecularFunctionCCR4-NOT complex binding

RC3H1 GARRE1

5.36e-053852GO:1905762
GeneOntologyMolecularFunctionproteoglycan binding

CFH THBS1 PTPRF ITGAM

6.56e-0551854GO:0043394
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA2D1 CACNA2D2 CACNA1I GRIN2B GRM7 KCNH5

1.27e-04182856GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA2D1 CACNA2D2 CACNA1I GRIN2B GRM7 KCNH5

1.35e-04184856GO:0022832
GeneOntologyMolecularFunctioncalcium channel activity

CACNA2D1 CACNA2D2 CACNA1I GRIN2B GRM7

2.26e-04129855GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA2D1 CACNA2D2 CACNA1I GRIN2B GRM7

4.67e-04151855GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA2D1 CACNA2D2 CACNA1I GRM7 KCNH5

4.81e-04152855GO:0022843
GeneOntologyMolecularFunctiongated channel activity

CACNA2D1 CACNA2D2 SCNN1A CACNA1I GRIN2B GRM7 KCNH5

5.56e-04334857GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA2D1 CACNA2D2 SCNN1A CACNA1I GRIN2B GRM7 KCNH5

6.50e-04343857GO:0005261
GeneOntologyMolecularFunctionamyloid-beta binding

APBB3 APBB2 GRIN2B ITGAM

9.46e-04102854GO:0001540
GeneOntologyMolecularFunctionglycosaminoglycan binding

CFH THBS1 PTPRF REG3G REG3A ITGAM

9.97e-04268856GO:0005539
GeneOntologyMolecularFunctioncomplement component C3b binding

CFH ITGAM

1.15e-0312852GO:0001851
GeneOntologyMolecularFunctionglutamate binding

GRIN2B GRM7

1.58e-0314852GO:0016595
GeneOntologyMolecularFunctioncarbohydrate binding

SFTPA2 SFTPD REG3G SFTPA1 REG3A ENDOU

2.09e-03310856GO:0030246
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRF PTPRH

2.34e-0317852GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRF PTPRH

2.34e-0317852GO:0019198
GeneOntologyBiologicalProcesscell-cell adhesion

CFH ILDR2 THBS1 PTPRF HLA-DMB SFTPD F2RL3 RC3H1 CNTN5 FER TMEM131L REG3A PCDHA4 PCDHA3 ITGAE ITGAL ITGAM YTHDF2

3.14e-0710778518GO:0098609
GeneOntologyBiologicalProcessdetection of monosaccharide stimulus

REG3G REG3A

5.02e-053852GO:0034287
GeneOntologyBiologicalProcessdetection of hexose stimulus

REG3G REG3A

5.02e-053852GO:0009732
GeneOntologyBiologicalProcessdetection of carbohydrate stimulus

REG3G REG3A

5.02e-053852GO:0009730
GeneOntologyBiologicalProcesspositive regulation of detection of glucose

REG3G REG3A

5.02e-053852GO:2000972
GeneOntologyBiologicalProcessregulation of detection of glucose

REG3G REG3A

5.02e-053852GO:2000970
GeneOntologyBiologicalProcessdetection of glucose

REG3G REG3A

5.02e-053852GO:0051594
GeneOntologyBiologicalProcessphagocytosis

THBS1 SFTPA2 SFTPD SFTPA1 ITGAL ITGAM PLD4

1.38e-04274857GO:0006909
GeneOntologyBiologicalProcessleukocyte cell-cell adhesion

CFH ILDR2 THBS1 HLA-DMB SFTPD RC3H1 TMEM131L ITGAL ITGAM

1.75e-04486859GO:0007159
GeneOntologyCellularComponentmultivesicular body

PGA4 SFTPA2 HLA-DMB SFTPD SFTPA1 PGA5 PGA3

6.95e-0888857GO:0005771
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

2.24e-067853GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

1.05e-0511853GO:0031906
GeneOntologyCellularComponentlate endosome

PGA4 SFTPA2 HLA-DMB SFTPD WDR81 SFTPA1 GRIN2B PGA5 PGA3

1.20e-05348859GO:0005770
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA2D1 CACNA2D2 CACNA1I CATSPERG

3.65e-0546854GO:0005891
GeneOntologyCellularComponentside of membrane

CFH THBS1 PRSS8 CNTN5 CD109 FER SCNN1A FES ITGAE ITGAL ITGAM SPRN

2.12e-048758512GO:0098552
GeneOntologyCellularComponentcalcium channel complex

CACNA2D1 CACNA2D2 CACNA1I CATSPERG

2.24e-0473854GO:0034704
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA2D1 CACNA2D2 GRIN2B GRM7

2.89e-0478854GO:0048787
GeneOntologyCellularComponentintegrin complex

ITGAE ITGAL ITGAM

2.96e-0432853GO:0008305
GeneOntologyCellularComponentcation channel complex

CACNA2D1 CACNA2D2 SCNN1A CACNA1I CATSPERG KCNH5

3.95e-04235856GO:0034703
GeneOntologyCellularComponentGABA-ergic synapse

CACNA2D1 DRD3 CACNA2D2 CNTN5 GRM7

5.53e-04164855GO:0098982
GeneOntologyCellularComponentendosome lumen

PGA4 PGA5 PGA3

7.12e-0443853GO:0031904
GeneOntologyCellularComponentendosome

PGA4 SFTPA2 PTPRF HLA-DMB SFTPD PACSIN1 APBB2 WDR81 SFTPA1 GRIN2B PGA5 PGA3 PLD4

8.32e-0411678513GO:0005768
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA2D1 CACNA2D2 SCNN1A CACNA1I GRIN2B CATSPERG KCNH5

8.80e-04378857GO:0034702
GeneOntologyCellularComponentplasma membrane protein complex

CACNA2D1 HLA-DMB CACNA2D2 CACNA1I GRIN2B ITGAE ITGAL ITGAM CATSPERG KCNH5

1.30e-037858510GO:0098797
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA2D1 CACNA2D2 SCNN1A COX7A1 CACNA1I GRIN2B CATSPERG KCNH5

1.30e-03523858GO:1902495
GeneOntologyCellularComponentsecretory vesicle

CACNA2D1 THBS1 SFTPA2 CD109 SCNN1A REG3G SFTPA1 REG3A CPA3 GRIN2B ITGAL ITGAM DOC2B

1.51e-0312468513GO:0099503
GeneOntologyCellularComponenttransporter complex

CACNA2D1 CACNA2D2 SCNN1A COX7A1 CACNA1I GRIN2B CATSPERG KCNH5

1.78e-03550858GO:1990351
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGAE ITGAL ITGAM

1.79e-0359853GO:0098636
GeneOntologyCellularComponentsynaptic membrane

CACNA2D1 DRD3 PTPRF CACNA2D2 PACSIN1 CNTN5 GRIN2B GRM7

2.55e-03583858GO:0097060
GeneOntologyCellularComponentpresynaptic active zone

CACNA2D1 CACNA2D2 GRIN2B GRM7

2.63e-03141854GO:0048786
GeneOntologyCellularComponentsecretory granule

CACNA2D1 THBS1 SFTPA2 CD109 SCNN1A REG3G SFTPA1 REG3A CPA3 ITGAL ITGAM

2.64e-0310148511GO:0030141
GeneOntologyCellularComponentlamellar body

SFTPA2 SFTPA1

3.26e-0321852GO:0042599
GeneOntologyCellularComponentpostsynaptic density membrane

DRD3 PTPRF PACSIN1 GRIN2B

3.87e-03157854GO:0098839
MousePhenoincreased susceptibility to Orthomyxoviridae infection

SFTPA2 SFTPD REG3G SFTPA1

2.66e-0537664MP:0020946
MousePhenoabnormal Bruch membrane morphology

CFH PPARGC1A MFRP

3.53e-0514663MP:0005239
MousePhenoabnormal cytokine level

SFTPA2 SFTPD PACSIN1 RC3H1 SFTPA1 PLCD1 KLHDC10 ITGAL USP20 PLD4

6.53e-054706610MP:0008713
MousePhenoabnormal intercellular signaling peptide or protein level

SFTPA2 SFTPD PACSIN1 RC3H1 SFTPA1 PLCD1 KLHDC10 ITGAL USP20 PLD4

7.79e-054806610MP:0008835
MousePhenoabnormal susceptibility to Orthomyxoviridae infection

SFTPA2 SFTPD REG3G SFTPA1

1.20e-0454664MP:0020945
DomainAspartic_peptidase_N

PGA4 PGA5 PGC PGA3

1.38e-087854IPR012848
DomainA1_Propeptide

PGA4 PGA5 PGC PGA3

1.38e-087854PF07966
DomainAspartic_peptidase_A1

PGA4 PGA5 PGC PGA3

8.22e-0810854IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 PGC PGA3

8.22e-0810854IPR033121
DomainAsp

PGA4 PGA5 PGC PGA3

8.22e-0810854PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 PGC PGA3

8.22e-0810854PS51767
Domain-

PGA4 PGA5 PGC PGA3

1.92e-07128542.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 PGC PGA3

1.92e-0712854PS00141
DomainAspartic_peptidase_AS

PGA4 PGA5 PGC PGA3

2.77e-0713854IPR001969
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGC PGA3

9.09e-0717854IPR021109
DomainC-type_lectin_CS

SFTPA2 SFTPD REG3G SFTPA1 REG3A

1.46e-0643855IPR018378
DomainVWA

CACNA2D1 CACNA2D2 ITGAE ITGAL ITGAM

5.52e-0656855PF00092
DomainIntegrin_alpha

ITGAE ITGAL ITGAM

1.46e-0511853PF00357
DomainTyr-prot_kinase_Fes/Fps

FER FES

2.05e-052852IPR016250
DomainC_TYPE_LECTIN_1

SFTPA2 SFTPD REG3G SFTPA1 REG3A

3.19e-0580855PS00615
DomainVWFA

CACNA2D1 CACNA2D2 ITGAE ITGAL ITGAM

3.59e-0582855PS50234
DomainVWA

CACNA2D1 CACNA2D2 ITGAE ITGAL ITGAM

4.04e-0584855SM00327
DomainLectin_C

SFTPA2 SFTPD REG3G SFTPA1 REG3A

4.04e-0584855PF00059
DomainCLECT

SFTPA2 SFTPD REG3G SFTPA1 REG3A

4.04e-0584855SM00034
DomainC_TYPE_LECTIN_2

SFTPA2 SFTPD REG3G SFTPA1 REG3A

4.27e-0585855PS50041
DomainC-type_lectin-like

SFTPA2 SFTPD REG3G SFTPA1 REG3A

4.52e-0586855IPR001304
DomainIntegrin_alpha_C_CS

ITGAE ITGAL ITGAM

4.88e-0516853IPR018184
DomainIntegrin_alpha-2

ITGAE ITGAL ITGAM

7.07e-0518853IPR013649
DomainIntegrin_alpha2

ITGAE ITGAL ITGAM

7.07e-0518853PF08441
DomainIntegrin_alpha

ITGAE ITGAL ITGAM

7.07e-0518853IPR000413
DomainINTEGRIN_ALPHA

ITGAE ITGAL ITGAM

7.07e-0518853PS00242
Domain-

SFTPA2 SFTPD REG3G SFTPA1 REG3A

8.04e-05978553.10.100.10
DomainInt_alpha_beta-p

ITGAE ITGAL ITGAM

8.36e-0519853IPR013519
DomainInt_alpha

ITGAE ITGAL ITGAM

8.36e-0519853SM00191
DomainC-type_lectin-like/link

SFTPA2 SFTPD REG3G SFTPA1 REG3A

8.86e-0599855IPR016186
DomainVWF_A

CACNA2D1 CACNA2D2 ITGAE ITGAL ITGAM

8.86e-0599855IPR002035
DomainVGCC_alpha2

CACNA2D1 CACNA2D2

1.22e-044852PF08473
DomainVDCC_a2/dsu

CACNA2D1 CACNA2D2

1.22e-044852IPR013680
DomainCTDL_fold

SFTPA2 SFTPD REG3G SFTPA1 REG3A

1.28e-04107855IPR016187
DomainFCH

PACSIN1 FER FES

1.32e-0422853PF00611
DomainFG_GAP

ITGAE ITGAL ITGAM

1.32e-0422853PS51470
DomainFCH

PACSIN1 FER FES

1.32e-0422853SM00055
DomainFCH_dom

PACSIN1 FER FES

1.51e-0423853IPR001060
DomainFG-GAP

ITGAE ITGAL ITGAM

1.72e-0424853PF01839
DomainFG-GAP

ITGAE ITGAL ITGAM

1.72e-0424853IPR013517
DomainF_BAR

PACSIN1 FER FES

1.95e-0425853IPR031160
DomainIntegrin_dom

ITGAE ITGAL ITGAM

1.95e-0425853IPR032695
DomainF_BAR

PACSIN1 FER FES

1.95e-0425853PS51741
DomainVWA_N

CACNA2D1 CACNA2D2

2.03e-045852IPR013608
DomainVWA_N

CACNA2D1 CACNA2D2

2.03e-045852PF08399
DomainCollagen

SFTPA2 SFTPD SFTPA1 MFRP

6.11e-0485854IPR008160
DomainCollagen

SFTPA2 SFTPD SFTPA1 MFRP

6.11e-0485854PF01391
DomainApc4_WD40_dom

WRAP73 WDR17

3.69e-0320852IPR024977
DomainANAPC4_WD40

WRAP73 WDR17

3.69e-0320852PF12894
DomainIg-like_fold

ILDR2 PTPRF PTPRH PTCRA HLA-DMB PLXNC1 VSTM2L CNTN5 CEACAM16

4.76e-03706859IPR013783
DomainG_patch

ZGPAT SUGP2

4.87e-0323852SM00443
DomainG_patch_dom

ZGPAT SUGP2

4.87e-0323852IPR000467
DomainG_PATCH

ZGPAT SUGP2

4.87e-0323852PS50174
DomainG-patch

ZGPAT SUGP2

4.87e-0323852PF01585
DomainPAS

AHRR KCNH5

5.74e-0325852PF00989
DomainPAS_fold

AHRR KCNH5

5.74e-0325852IPR013767
DomainPID

APBB3 APBB2

7.17e-0328852PF00640
PathwayREACTOME_SURFACTANT_METABOLISM

PGA4 SFTPA2 SFTPD SFTPA1 PGA5 PGA3

2.52e-0930606M27566
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGC PGA3

9.57e-0811604M39726
PathwayREACTOME_DEFECTIVE_CSF2RB_CAUSES_SMDP5

SFTPA2 SFTPD SFTPA1

4.04e-068603M27575
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM

SFTPA2 SFTPD SFTPA1

8.61e-0610603M27573
PathwayREACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS

SFTPA2 SFTPD SFTPA1

2.58e-0514603MM15011
PathwayREACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS

SFTPA2 SFTPD SFTPA1

3.95e-0516603M925
PathwayREACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND

SFTPA2 SFTPD SFTPA1

1.07e-0422603M27571
PathwayREACTOME_REGULATION_OF_TLR_BY_ENDOGENOUS_LIGAND

SFTPA2 SFTPD SFTPA1

1.07e-0422603MM15284
PathwayREACTOME_SURFACTANT_METABOLISM

SFTPA2 SFTPD SFTPA1

1.22e-0423603MM15279
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA2D1 CACNA2D2 CACNA1I

1.58e-0425603M47948
PathwayPID_INTEGRIN_CS_PATHWAY

ITGAE ITGAL ITGAM

1.78e-0426603M47
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

THBS1 ITGAE ITGAL ITGAM

3.03e-0476604MM14867
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

THBS1 ITGAE ITGAL ITGAM

4.64e-0485604M16441
PathwayBIOCARTA_NEUTROPHIL_PATHWAY

ITGAL ITGAM

4.91e-048602MM1536
PathwayBIOCARTA_NEUTROPHIL_PATHWAY

ITGAL ITGAM

4.91e-048602M22010
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

CNTN5 CD109 PIGG SPRN

6.53e-0493604M26985
PathwayWP_COMPLEMENT_SYSTEM

CFH THBS1 SFTPA2 SFTPA1

7.36e-0496604M39581
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

CNTN5 CD109 PIGG SPRN

8.26e-0499604MM14624
PathwayPID_HNF3A_PATHWAY

SFTPA2 SFTPD SFTPA1

8.57e-0444603M285
PathwayBIOCARTA_MONOCYTE_PATHWAY

ITGAL ITGAM

9.56e-0411602MM1436
PathwayBIOCARTA_MONOCYTE_PATHWAY

ITGAL ITGAM

9.56e-0411602M4956
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGC PGA3

3.65e-11487423047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGC PGA3

3.65e-11487411915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGC PGA3

3.65e-1148748322031
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGC PGA3

3.65e-11487412698190
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGC PGA3

1.82e-10587422066020
Pubmed

ErbB4 regulates the timely progression of late fetal lung development.

SFTPA2 SFTPD SFTPA1 ITGAM

1.27e-09787420303366
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

1.51e-0838733017318
Pubmed

The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo.

SFTPA2 SFTPD SFTPA1

1.51e-08387312015304
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

1.51e-08387321989121
Pubmed

Surfactant proteins SP-A and SP-D: structure, function and receptors.

SFTPA2 SFTPD SFTPA1

1.51e-08387316213021
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

1.51e-0838739855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

1.51e-0838739797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

1.51e-0838732478370
Pubmed

Macrophage-independent fungicidal action of the pulmonary collectins.

SFTPA2 SFTPD SFTPA1

1.51e-08387312857753
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

1.51e-0838733815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

1.51e-08387310675278
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

1.51e-0838737926498
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

1.51e-0838733780036
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

1.51e-0838739561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

1.51e-08387321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

1.51e-08387319800305
Pubmed

Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D.

SFTPA2 SFTPD SFTPA1

1.51e-08387315588319
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

1.51e-0838732901984
Pubmed

Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema.

SFTPA2 SFTPD SFTPA1

1.51e-08387312376353
Pubmed

Surfactant protein A and surfactant protein D in health and disease.

SFTPA2 SFTPD SFTPA1

1.51e-0838739688929
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

1.51e-0838733839486
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

1.51e-08387324170207
Pubmed

Surfactant protein A and D gene polymorphisms and protein expression in victims of sudden infant death.

SFTPA2 SFTPD SFTPA1

1.51e-08387318983439
Pubmed

SP-A1, SP-A2 and SP-D gene polymorphisms in severe acute respiratory syncytial infection in Chilean infants.

SFTPA2 SFTPD SFTPA1

1.51e-08387321601013
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

1.51e-0838733467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

1.51e-0838734586732
Pubmed

Surfactant-associated protein A provides critical immunoprotection in neonatal mice.

SFTPA2 SFTPD SFTPA1

1.51e-08387317967856
Pubmed

Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help?

SFTPA2 SFTPD SFTPA1

1.51e-08387324960334
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

1.51e-0838733014868
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

1.51e-0838732892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

1.51e-08387324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

1.51e-0838731455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

1.51e-0838732831884
Pubmed

Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice.

SFTPA2 SFTPD SFTPA1

1.51e-08387318996902
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

1.51e-0838732799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

1.51e-08387319872561
Pubmed

Expression of surfactant proteins SP-A and SP-D in murine decidua and immunomodulatory effects on decidual macrophages.

SFTPA2 SFTPD SFTPA1

1.51e-08387326421960
Pubmed

Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia.

SFTPA2 SFTPD SFTPA1

1.51e-08387326849628
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

1.51e-0838731968039
Pubmed

A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.

PGA4 PGA5 PGC

1.51e-0838732515193
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

1.51e-0838732032552
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

1.51e-0838738053437
Pubmed

Surfactant protein A modulates cell surface expression of CR3 on alveolar macrophages and enhances CR3-mediated phagocytosis.

SFTPA2 SFTPA1 ITGAM

1.51e-08387319155216
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

1.51e-0838731812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

1.51e-0838737923573
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

1.51e-0838732566575
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

1.51e-0838739061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

1.51e-08387312588289
Pubmed

Lung surfactant proteins involved in innate immunity.

SFTPA2 SFTPD SFTPA1

1.51e-08387310047533
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

1.51e-0838732229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

1.51e-08387325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

1.51e-08387319890696
Pubmed

Role of surfactant proteins A and D in sepsis-induced acute kidney injury.

SFTPA2 SFTPD SFTPA1

1.51e-08387325255378
Pubmed

Pulmonary collectins modulate strain-specific influenza a virus infection and host responses.

SFTPA2 SFTPD SFTPA1

1.51e-08387315280465
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

1.51e-08387323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

1.51e-08387311566730
Pubmed

Localization and developmental expression of surfactant proteins D and A in the respiratory tract of the mouse.

SFTPA2 SFTPD SFTPA1

1.51e-0838738725251
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

1.51e-0838731956484
Pubmed

Change of surfactant protein D and A after renal ischemia reperfusion injury.

SFTPA2 SFTPD SFTPA1

1.51e-08387331877195
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

1.51e-0838738540382
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

1.51e-0838738244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

1.51e-08387321407214
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

1.51e-08387322992016
Pubmed

Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx.

SFTPA2 SFTPD SFTPA1

1.51e-08387338375572
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

1.51e-08387320981206
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

1.51e-0838736774973
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

1.51e-0838738504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

1.51e-08387321970995
Pubmed

Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis.

SFTPA2 SFTPD SFTPA1

1.51e-08387320413160
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

1.51e-0838736300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

1.51e-08387322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

1.51e-08387324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

1.51e-0838738038355
Pubmed

Susceptibility of mice genetically deficient in the surfactant protein (SP)-A or SP-D gene to pulmonary hypersensitivity induced by antigens and allergens of Aspergillus fumigatus.

SFTPA2 SFTPD SFTPA1

1.51e-08387315905537
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

1.51e-08387320428942
Pubmed

Surfactant proteins A and D enhance pulmonary clearance of Pseudomonas aeruginosa.

SFTPA2 SFTPD SFTPA1

1.51e-08387316456184
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

1.51e-0838732227273
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

1.51e-0838739525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

1.51e-0838737886402
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

1.51e-08387323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

1.51e-08387324125879
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

1.51e-08387317379991
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

1.51e-0838738751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

1.51e-0838733554488
Pubmed

Dispensability of surfactant proteins A and D in immune control of Mycobacterium tuberculosis infection following aerosol challenge of mice.

SFTPA2 SFTPD SFTPA1

1.51e-08387321199913
Pubmed

Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli.

SFTPA2 SFTPD SFTPA1

1.51e-08387326511057
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

1.51e-08387321547904
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

1.51e-08387323521833
Pubmed

Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex.

SFTPA2 SFTPD SFTPA1

6.04e-08487312244199
Pubmed

Retinal degeneration mutation in Sftpa1tm1Kor/J and Sftpd -/- targeted mice.

SFTPA2 SFTPD SFTPA1

6.04e-08487329969487
Pubmed

Characterization of the mouse collectin gene locus.

SFTPA2 SFTPD SFTPA1

6.04e-08487310423401
Pubmed

Effect of lung surfactant collectins on bronchoalveolar macrophage interaction with Blastomyces dermatitidis: inhibition of tumor necrosis factor alpha production by surfactant protein D.

SFTPA2 SFTPD SFTPA1

6.04e-08487316861641
Pubmed

Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin.

SFTPA2 SFTPD SFTPA1

6.04e-08487315145932
Pubmed

Expression and localization of collectins in feto-maternal tissues of human first trimester spontaneous abortion and abortion prone mouse model.

SFTPA2 SFTPD SFTPA1

6.04e-08487326603976
Pubmed

Testicular expression of SP-A, SP-D and MBL-A is positively regulated by testosterone and modulated by lipopolysaccharide.

SFTPA2 SFTPD SFTPA1

6.04e-08487327262512
InteractionSFTPA1 interactions

SFTPA2 SFTPD SFTPA1

4.28e-068873int:SFTPA1
InteractionALKAL2 interactions

CACNA2D1 CACNA2D2 CD109

1.25e-0511873int:ALKAL2
InteractionPLA2G5 interactions

CACNA2D1 CACNA2D2 CD109

1.66e-0512873int:PLA2G5
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SFTPA2 SFTPD REG3G SFTPA1 REG3A

1.95e-07415851298
GeneFamilyCollectins

SFTPA2 SFTPD SFTPA1

3.70e-0610583491
GeneFamilyCD molecules|Integrin alpha subunits

ITGAE ITGAL ITGAM

2.47e-05185831160
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

PACSIN1 FER FES

5.30e-05235831288
GeneFamilyCalcium voltage-gated channel subunits

CACNA2D1 CACNA2D2 CACNA1I

7.73e-0526583253
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRF PTPRH

2.04e-0321582813
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

ZGPAT SUGP2

2.24e-0322582579
GeneFamilyZinc fingers CCCH-type

ZGPAT RC3H1

5.62e-033558273
GeneFamilyComplement system|Sushi domain containing

CFH ITGAM

5.94e-0336582492
GeneFamilyPhospholipases

PLCD1 PLD4

8.02e-0342582467
GeneFamilyADAM metallopeptidase domain containing|CD molecules

PLXNC1 CD109 ITGAE ITGAL ITGAM

8.53e-03394585471
CoexpressionNABA_ECM_AFFILIATED

SFTPA2 SFTPD PLXNC1 REG3G SFTPA1 REG3A MFRP

9.12e-07158867MM17063
CoexpressionTRAVAGLINI_LUNG_SIGNALING_ALVEOLAR_EPITHELIAL_TYPE_2_CELL

SFTPA2 CACNA2D2 SFTPD SFTPA1 PGC

3.71e-0671865M41661
CoexpressionNABA_ECM_AFFILIATED

SFTPA2 SFTPD PLXNC1 REG3G SFTPA1 REG3A

2.09e-05170866M5880
CoexpressionDESCARTES_FETAL_ADRENAL_MEGAKARYOCYTES

THBS1 INAFM2 PTCRA F2RL3 CPA3

3.75e-05114865M40146
CoexpressionGSE6259_BCELL_VS_CD8_TCELL_UP

FAM171A1 AHRR CD109 TMEM131L INTS9 ITGAL

4.25e-05193866M6735
CoexpressionGSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN

CFH CACNA2D1 AHRR SUGP2 PLXNC1 SCNN1A

5.18e-05200866M6894
CoexpressionGSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN

THBS1 HLA-DMB REG3G REG3A GRIN2B PLD4

5.18e-05200866M7136
CoexpressionGSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_DN

PRSS8 PTCRA PACSIN1 FES WDR81 GBA2

5.18e-05200866M6956
CoexpressionTRAVAGLINI_LUNG_ALVEOLAR_EPITHELIAL_TYPE_2_CELL

SFTPA2 CACNA2D2 SFTPD SFTPA1 PGC

8.68e-05136865M41660
CoexpressionAtlasalpha beta T cells, preT.DN3A.Th, Lin-/lo CD25hi CD44- CD28-, Thymus, avg-3

PTPRF PTCRA ENDOU CPA3 SPATS2 PLD4

1.64e-0689866GSM791146_100
ToppCell343B-Epithelial_cells|343B / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

1.97e-101988790756a5d01572343abce77e7584b816c2c2e9d9c7
ToppCell(7)_Epithelial-D_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

3.83e-09190878832d6d3ad14665e50623afe1b8586ccae1a97de5
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

3.99e-09191878d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCell(7)_Epithelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

4.51e-09194878413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCellAT2|World / shred by cell class for parenchyma

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

4.51e-09194878e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell356C-Epithelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

4.70e-09195878d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

4.70e-09195878b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCell343B|World / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

4.70e-091958782290911fde6efacfa38b985a2541322968bee42d
ToppCellnormal_Lung-Epithelial_cells|normal_Lung / Location, Cell class and cell subclass

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

4.70e-091958787c90d887afde5c4d63352b5171be9987e2dfca58
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

4.89e-09196878345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.51e-091998787ebd89dff457f57a549eecee288c7a4b515b4018
ToppCellEpithelial_cells|World / lung cells shred on cell class, cell subclass, sample id

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.51e-09199878bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCelldistal-1-Epithelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.51e-091998789086dbb60863c3da2cc5d0a310f28596a01c52ca
ToppCellproximal|World / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFH PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

5.73e-0920087833f05ed458c889bf241580f513ce66797007248c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-0920087821d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-09200878c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellcellseq-Epithelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-09200878e4204c4b864346f47d76b0f0faae96f04fed5082
ToppCelldistal-Epithelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008780a97080f694738bb882787cee21b91a4d5757b7a
ToppCellproximal-Epithelial|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008783790dd13c4ff471e716e5a2950f196e3c386dbb1
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008783ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellproximal-3-Epithelial|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-0920087808858bb20630849ffb2192631e23466c242a1078
ToppCellBiopsy_Other_PF-Epithelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008781ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCellBiopsy_Control_(H.)-Epithelial|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008780afd93c4fdcc118bcfa77f3b59f6ff7d9293a7a4
ToppCellLung_Parenchyma-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-0920087833658d5d09e2eaff60f4dd88837d4252328eab63
ToppCellParenchyma_COVID-19-Epithelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-09200878d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCellParenchymal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-0920087816828c6a2be66bbbd805453325d6da719f2dea1b
ToppCellParenchymal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008784e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

5.73e-092008789970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

2.90e-08160877ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

2.90e-08160877b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

3.44e-0816487785f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

3.44e-08164877144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

4.06e-08168877e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

4.06e-0816887716b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

7.57e-081848770ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

7.57e-08184877369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

7.57e-081848772a8338e94937686a148b5433515700ca0f674058
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

8.45e-0818787711670a85db87cbb3e78022a589632173604b0940
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

8.45e-081878770277d4e54bd4d48f30241c2951a569209423fee8
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

9.09e-081898776f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCellAdult|World / Lineage, Cell type, age group and donor

SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

9.09e-081898775cd285bfad973125d46d704fec18b21266a63379
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

9.09e-08189877926b5fa3064b501a57ba78583e8af33532add455
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

9.42e-0819087727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

9.42e-08190877459811e88d3001816c2d89034e0921c24918c17f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A ACSS2 PGC

9.76e-081918776cb2c107bc674aa173b4009f320a1687a76f3979
ToppCell(7)_Epithelial-E_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

9.76e-081918770fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 ACSS2 PGC

1.01e-0719287706013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS8 SFTPA2 CACNA2D2 SFTPD CPA3 ACSS2 PGC

1.05e-07193877043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRSS8 SFTPA2 CACNA2D2 SFTPD SFTPA1 ACSS2 PGC

1.12e-071958776867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRSS8 SFTPA2 CACNA2D2 SFTPD SFTPA1 ACSS2 PGC

1.12e-07195877955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.12e-071958779406866f99555198a9be311fbd65751b70f35446
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.12e-071958771798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

1.16e-0719687793a5d9b8bcff7d07596ef1f4f2b74f043835fc69
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

1.16e-071968774715f19f844e7244fc4bc446cba7c8088c600fc3
ToppCellLAM-Epithelial|LAM / Condition, Lineage and Cell class

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.21e-07197877e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.21e-07197877f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.21e-07197877f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCellAT2_cells|World / lung cells shred on cell class, cell subclass, sample id

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.25e-0719887792c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877b44d74895846e2ac144438b73e0ca91e3949c16c
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.29e-071998774b374a5de82b4614d3d8a00202ea6cb8f1fd8104
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-0719987783ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Transitional_AT2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.29e-071998779e8231c9007d8d963805a4c99e0905538ceb9b60
ToppCellASK428-Epithelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877a38a981cffa61c8444a980916de7414e689a1b63
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCellBiopsy_Control_(H.)-Epithelial-AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-071998775323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877e459d5aa63c83f960562be33cea8182b0556eabf
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.29e-07199877e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DRD3 PACSIN1 CHD5 CNTN5 CACNA1I DLX1 GRM7

1.34e-072008772f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-072008773c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877cf1991853e10c562edae9a0d71a209f35b07db80
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DRD3 PACSIN1 CHD5 CNTN5 CACNA1I DLX1 GRM7

1.34e-07200877bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellParenchyma_COVID-19-Epithelial-TX-Transitional_AT2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877dfa897ef5ce4744c77b6e5ee5a0d6d83229d1691
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-0720087765c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-0720087723088edc62bf7d4db890937bfd7925dc316fcc76
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-0720087740e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.34e-072008778d1c78dd829cbc290820d5118f24ff7f828a8622
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877b2d61bc3afac0d78aa30082760da5b1a15d1fad2
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-0720087735c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DRD3 PACSIN1 CHD5 CNTN5 CACNA1I DLX1 GRM7

1.34e-07200877dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-072008777618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS8 SFTPA2 PTPRF SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877992bd6b1feac2afded6eb927ac95ddf5cfef961c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS8 SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-0720087723b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCelldistal-3-Epithelial|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS8 SFTPA2 PTPRF CACNA2D2 SFTPD SFTPA1 PGC

1.34e-07200877698c09d383b652178e4e150151139031b6e891bc
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SFTPA2 PTPRF CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

1.34e-07200877cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFH PTPRF CHD5 WDR81 GRM7 PGA3

2.06e-07129876a60935ff9c5a841899ccfe90531533ba4c546df3
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 SCNN1A TMEM131L ITGAM SPRN PLD4

1.01e-0616987615a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FAM171A1 F2RL3 COX7A1 PCDHA3 MSH4 GRIN2B

1.01e-061698768889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 SFTPD SCNN1A SFTPA1 PGC

1.12e-06172876a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

PRSS8 SFTPA2 SFTPD SCNN1A SFTPA1 PGC

1.12e-0617287626006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCellAT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SFTPA2 CACNA2D2 SFTPD SFTPA1 ACSS2 PGC

1.99e-0619087646dfab02c1b4a403b7efc871707b6a189eefd4c4
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

SFTPA2 CACNA2D2 SFTPD SCNN1A SFTPA1 PGC

2.05e-06191876276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

SFTPA2 CACNA2D2 SFTPD SFTPA1 ACSS2 PGC

2.12e-0619287658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SFTPA2 CACNA2D2 SFTPD SFTPA1 PGC

3.55e-0650515GAVISH_3CA_MALIGNANT_METAPROGRAM_31_ALVEOLAR
ComputationalGenes in the cancer module 412.

ITGAE ITGAL ITGAM

2.78e-0513513MODULE_412
ComputationalGenes in the cancer module 275.

ITGAE ITGAL ITGAM

5.40e-0516513MODULE_275
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SFTPA2 SFTPD SFTPA1 PGC

8.81e-0550514GAVISH_3CA_METAPROGRAM_EPITHELIAL_ALVEOLAR
DrugLandel

CACNA2D1 CACNA1I PGC

4.30e-069863CID000163838
Drugcaffeine

CACNA2D1 AHRR DRD3 CACNA2D2 COX7A1 CACNA1I CYP4F12 PLCD1 GRIN2B GRM7 GBA2

8.63e-065628611CID000002519
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; HL60; HT_HG-U133A

ZGPAT THBS1 PTCRA APBB2 PLCD1 SPATS2 USP20

9.52e-061968672969_UP
Diseasenewborn respiratory distress syndrome (biomarker_via_orthology)

SFTPA2 SFTPD SFTPA1

4.27e-076833DOID:12716 (biomarker_via_orthology)
Diseasenewborn respiratory distress syndrome (is_implicated_in)

SFTPA2 SFTPD SFTPA1

7.45e-077833DOID:12716 (is_implicated_in)
Diseasebacterial pneumonia (biomarker_via_orthology)

SFTPA2 SFTPD SFTPA1

7.64e-0614833DOID:874 (biomarker_via_orthology)
Diseasetumor necrosis factor receptor superfamily member 6B measurement

CFH ZGPAT

2.34e-053832EFO_0020815
Diseaselevel of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum

SFTPA2 SFTPA1

7.77e-055832OBA_2042200
Diseaseacute pancreatitis (implicated_via_orthology)

REG3G REG3A

7.77e-055832DOID:2913 (implicated_via_orthology)
Diseaselevel of prosaposin in blood serum

SFTPA2 SFTPA1

7.77e-055832OBA_2044552
Diseasemediator of RNA polymerase II transcription subunit 1 measurement

CFH PTCRA

1.16e-046832EFO_0008228
Diseasepulmonary alveolar proteinosis (is_marker_for)

SFTPD SFTPA1

1.16e-046832DOID:12120 (is_marker_for)
Diseaselung disease (biomarker_via_orthology)

SFTPA2 SFTPD SFTPA1

1.32e-0435833DOID:850 (biomarker_via_orthology)
Diseaseunipolar depression

CFH CACNA2D1 PLXNC1 FAM78B CNTN5 FER INTS9 PCDHA4 PCDHA3 GRIN2B GRM7 KCNH5

1.37e-0412068312EFO_0003761
Diseaseobsolete_interleukin-1 alpha measurement

CFH REG3G

1.63e-047832EFO_0802653
Diseasesciatic neuropathy (biomarker_via_orthology)

REG3G REG3A CACNA1I GRIN2B

1.79e-0499834DOID:11446 (biomarker_via_orthology)
Diseaseplacental insufficiency (biomarker_via_orthology)

PPARGC1A GRIN2B

2.16e-048832DOID:3891 (biomarker_via_orthology)
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 4 measurement

SFTPA2 SFTPA1

2.16e-048832EFO_0801768
Diseasediabetic retinopathy (biomarker_via_orthology)

PPARGC1A THBS1 ITGAM

2.80e-0445833DOID:8947 (biomarker_via_orthology)
Diseasepneumonia (implicated_via_orthology)

REG3G REG3A

3.47e-0410832DOID:552 (implicated_via_orthology)
Diseaserespiratory syncytial virus infectious disease (is_implicated_in)

SFTPD SFTPA1

3.47e-0410832DOID:1273 (is_implicated_in)
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

SFTPA2 SFTPA1

5.07e-0412832EFO_0801493
Diseasegranulins measurement

SFTPA2 SFTPA1

5.07e-0412832EFO_0008141
Diseasebronchopulmonary dysplasia (is_implicated_in)

SFTPD SFTPA1

5.98e-0413832DOID:11650 (is_implicated_in)
Diseaseasthma (biomarker_via_orthology)

SFTPA2 SFTPD SFTPA1

6.23e-0459833DOID:2841 (biomarker_via_orthology)
DiseaseHamman-Rich syndrome

SFTPA2 SFTPA1

6.96e-0414832C0085786
Disease1-methylurate measurement

PTPRF GRM7

6.96e-0414832EFO_0021173
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

PPARGC1A REG3G REG3A ITGAM

8.01e-04147834DOID:9352 (biomarker_via_orthology)
Diseaseobesity (biomarker_via_orthology)

PPARGC1A SFTPA2 PTPRF SFTPA1

8.01e-04147834DOID:9970 (biomarker_via_orthology)
Diseaselupus nephritis (is_implicated_in)

CFH ITGAM

1.16e-0318832DOID:0080162 (is_implicated_in)
Diseasesinusitis (is_marker_for)

SFTPD SFTPA1

1.16e-0318832DOID:0050127 (is_marker_for)
Diseaserespiratory syncytial virus infectious disease (is_marker_for)

SFTPD SFTPA1

1.16e-0318832DOID:1273 (is_marker_for)
Diseaseepilepsy (implicated_via_orthology)

CACNA2D2 COX7A1 GRIN2B KCNH5

1.17e-03163834DOID:1826 (implicated_via_orthology)
Diseaseschizophrenia (is_implicated_in)

DRD3 CACNA1I GRIN2B

1.40e-0378833DOID:5419 (is_implicated_in)
DiseaseFamilial Idiopathic Pulmonary Fibrosis

SFTPA2 SFTPA1

1.44e-0320832C4721952
Diseasefeeling miserable measurement

RC3H1 CNTN5 CACYBP

1.45e-0379833EFO_0009598
Diseasecardiovascular system disease (is_implicated_in)

CFH PPARGC1A

1.59e-0321832DOID:1287 (is_implicated_in)
DiseaseIdiopathic Pulmonary Fibrosis

SFTPA2 SFTPA1

1.59e-0321832C1800706
DiseaseAllodynia

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0458247
DiseaseMechanical Allodynia

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C2936719
DiseaseHyperalgesia, Secondary

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0751212
DiseaseHyperalgesia, Primary

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0751211
DiseaseHyperalgesia, Thermal

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0751214
DiseaseTactile Allodynia

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0751213
DiseaseHyperalgesia

CACNA2D1 DRD3 GRIN2B

1.74e-0384833C0020429
Diseaselung disease (is_implicated_in)

SFTPD SFTPA1

1.74e-0322832DOID:850 (is_implicated_in)
Diseaselung disease (is_marker_for)

SFTPD SFTPA1

1.74e-0322832DOID:850 (is_marker_for)
Diseasecoffee consumption measurement

PPARGC1A PTPRF CACNA2D2 FES

1.76e-03182834EFO_0006781
DiseaseHuntington's disease (is_implicated_in)

PPARGC1A GRIN2B

1.90e-0323832DOID:12858 (is_implicated_in)
Diseasecongenital diaphragmatic hernia (biomarker_via_orthology)

SFTPA2 SFTPA1

2.07e-0324832DOID:3827 (biomarker_via_orthology)
Diseasevisual epilepsy (biomarker_via_orthology)

DRD3 REG3G REG3A

2.11e-0390833DOID:11832 (biomarker_via_orthology)
Diseaseinterstitial lung disease (is_marker_for)

SFTPD SFTPA1

2.25e-0325832DOID:3082 (is_marker_for)
Diseasevisuospatial function measurement

WRAP73 GRIN2B

2.43e-0326832EFO_0803533
Diseaseadult respiratory distress syndrome (is_marker_for)

SFTPD SFTPA1

2.43e-0326832DOID:11394 (is_marker_for)
Diseasechronic obstructive pulmonary disease (is_marker_for)

PPARGC1A SFTPD SFTPA1

2.62e-0397833DOID:3083 (is_marker_for)
Diseasemacular degeneration (is_implicated_in)

CFH PPARGC1A

2.62e-0327832DOID:4448 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
AQEWGTGTPTEYSAF

AHRR

206

A9YTQ3
TYTTLYERNRGSGSW

CATSPERG

321

Q6ZRH7
DIAGTYYWHIPTGTT

APBB2

301

Q92870
GSATGVTRYYPATPW

CACNA2D2

251

Q9NY47
WYIDSTGGTLHPYQL

CHD5

691

Q8TDI0
GELLAYSWYAGPTLS

CEACAM16

46

Q2WEN9
DSDGVSYPWYGNTTE

FAM78B

106

Q5VT40
SYPWYGNTTETVTLV

FAM78B

111

Q5VT40
WYLSITRPTSSYTGS

B3GALT1

21

Q9Y5Z6
DIYYGIGPRTSWSTV

GLCE

336

O94923
SGGNAGSYIPSYTSW

DLX1

226

P56177
SWSDQTYPEGTQAIY

CFH

36

P08603
WITGHSYVTYGPLAN

ACSS2

361

Q9NR19
LGGTVYSLYSLGWAS

COX7A1

61

P24310
TSAQPTCDYGYGTWN

AKAP8L

21

Q9ULX6
SPSWLGAAQNYYSPI

CNTN5

66

O94779
DYSQYSPWSCDTIGS

RC3H1

806

Q5TC82
VTPLSSGYALGSSNW

INTS9

211

Q9NV88
GIDSSYYTGSLNWVP

PGA5

231

P0DJD9
YYTGSLNWVPVTVEG

PGA5

236

P0DJD9
GLSYNTTAFPNIWVG

MFRP

476

Q9BY79
SPVWGEGSYLSSYPT

PTCRA

231

Q6ISU1
SGYNAWLSYELQPGT

PCDHA3

601

Q9Y5H8
GSQLTWTYIAPQLGY

FAM171A1

266

Q5VUB5
SVSSSYLSWYQQKPG

IGKV3D-7

51

A0A0C4DH55
IGTPYRYNTSAGIWE

KCNH5

396

Q8NCM2
YIYNGHWDGLSASPS

ITGAE

616

P38570
YNYTSGAATGWPSMA

PLXNC1

251

O60486
RIYILGGGTSWTAYS

KLHDC10

271

Q6PID8
SLGGYPLAVRTYTWD

ENDOU

376

P21128
PITTGYTVKISNYGW

CACYBP

66

Q9HB71
GIDSSYYTGSLNWVP

PGA3

231

P0DJD8
YYTGSLNWVPVTVEG

PGA3

236

P0DJD8
SVSSYDRGQPYATEW

PACSIN1

346

Q9BY11
YPAGWRTDSSNYSPV

PLCD1

551

P51178
LSYPWDGTQSYSLFN

PPARGC1A

521

Q9UBK2
SPSAWGNLYGAYVPS

F2RL3

311

Q96RI0
ASYYWSLTGPDIGVN

PLD4

136

Q96BZ4
SGYNAWLSYELQPGT

PCDHA4

601

Q9UN74
AAGTYYWHVPSGSTQ

APBB3

41

O95704
AFGNYDPSGSTWLSA

CD109

976

Q6YHK3
SSYTPLPGSNYSEGW

HLA-DMB

246

P28068
YPISGSSLDWAYDLG

CPA3

356

P15088
PTWNETLTYYGITDE

DOC2B

191

Q14184
YADQTYDGWVTTGPS

GBA2

671

Q9HCG7
TYTWTPVNGTDYSLA

CACNA2D1

606

P54289
WTAPEALNYGRYSSE

FER

726

P16591
SLSSSRSSYYGPWGR

CACNA1I

966

Q9P0X4
GQWPGISDLSSDLYS

GARRE1

776

O15063
SATYSQGFTVWLGPI

CYP4F12

81

Q9HCS2
ANEAPFYLWGSSTSG

CCP110

756

O43303
SFPQGWSLGYQYPSS

KHDC4

586

Q7Z7F0
LGWNYVSTLASEGSY

GRM7

216

Q14831
SGTIWSYPNPYTSIS

CCDC168

2766

Q8NDH2
TPSVGSQGDQWYLGY

CCDC144A

26

A2RUR9
VTSYQLSAGYSRWPS

SCNN1A

481

P37088
SPELYSATTWLGYVN

DRD3

361

P35462
TLTWDSGNSEPVTYY

PTPRF

336

P10586
GIDSSYYTGSLNWVP

PGA4

231

P0DJD7
YYTGSLNWVPVTVEG

PGA4

236

P0DJD7
SNSYSYIWIGLHDPT

REG3G

96

Q6UW15
YYSLIWQPVGAGTSG

INAFM2

56

P0DMQ5
WTAPEALNYGRYSSE

FES

726

P07332
GNSYSYVWIGLHDPT

REG3A

96

Q06141
SGLFGSIWAPQSDVY

TMEM131L

1531

A2VDJ0
YSAGVLNDTWVSFPS

SIN3B

451

O75182
GYKSWTPQVGYSASS

MSH4

131

O15457
TSPGNEGVIYSLSWA

WDR17

431

Q8IZU2
WSPSSQFLAVGSYDG

WRAP73

231

Q9P2S5
SDGTPVNYTNWYRGE

SFTPA2

201

Q8IWL1
SNGPLLSTVGSYDWA

ITGAM

361

P11215
AGYLGYTVTWLPSRQ

ITGAL

401

P20701
NRPGVYTLASSYASW

PRSS8

266

Q16651
SDGTPVNYTNWYRGE

SFTPA1

201

Q8IWL2
SFGSSYSRVNYLTPW

TEPP

256

Q6URK8
YTPSSVNGSLWEAGI

TMEM237

336

Q96Q45
WYSSGSRYQSAPSQA

SPATS2

481

Q86XZ4
SYWDTNPTRAQGYSG

THBS1

1046

P07996
DSSLYTGQIYWAPVT

PGC

231

P20142
YPTGESLVYSNWAPG

SFTPD

326

P35247
NGTGPGIYSYRAWTS

SPRN

111

Q5BIV9
GIYSYRAWTSGAGPT

SPRN

116

Q5BIV9
AQLGPRSASYYAWSP

ILDR2

556

Q71H61
WYRQGITPSYPQGSS

TECPR1

1056

Q7Z6L1
SSWSQEYSFGPSAVL

SUGP2

156

Q8IX01
ETWTYLNSLYGGGPE

USP20

871

Q9Y2K6
GSGSPSYSLEIQWWY

VSTM2L

66

Q96N03
LTAFGTYAGPVLWAS

PIGG

886

Q5H8A4
TAPQGPGQSSYSYWV

PTPRH

496

Q9HD43
GTKVSAPYYSSWGTL

ZGPAT

131

Q8N5A5
TVRLWPLYNYGDGTS

WDR81

1671

Q562E7
SPSIGFSYSLGEAAW

YTHDF2

61

Q9Y5A9
SVGLTGYGYTWIVPS

GRIN2B

246

Q13224