Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RGL1 RALGDS ARHGEF28 DOCK10 PLCG1 ARHGEF4 DENND5A	3.93e-05	231	80	7	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGL1 RALGDS ARHGEF28 DOCK10 PLCG1 ARHGEF4 DENND5A ACAP2 PLXNB1	1.91e-04	507	80	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGL1 RALGDS ARHGEF28 DOCK10 PLCG1 ARHGEF4 DENND5A ACAP2 PLXNB1	1.91e-04	507	80	9	GO:0030695
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate binding	WASHC2C WASHC2A ACAP2	2.57e-04	31	80	3	GO:0080025
GeneOntologyMolecularFunction	retromer complex binding	WASHC2C WASHC2A	6.99e-04	10	80	2	GO:1905394
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	6.99e-04	10	80	2	GO:0140031
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate binding	WASHC2C BBS5 WASHC2A	9.41e-04	48	80	3	GO:0032266
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	ARHGEF28 PSEN1 ANK3 SKOR2 TET1 CAPRIN2 DOCK10 LGR4 SPG11 CAPRIN1 ZEB2 PLXNB1	2.61e-05	748	79	12	GO:0048667
GeneOntologyBiologicalProcess	neuron projection morphogenesis	ARHGEF28 PSEN1 ANK3 SKOR2 TET1 CAPRIN2 DOCK10 LGR4 SPG11 CAPRIN1 ZEB2 PLXNB1	5.14e-05	802	79	12	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	ARHGEF28 PSEN1 ANK3 SKOR2 TET1 CAPRIN2 DOCK10 LGR4 SPG11 CAPRIN1 ZEB2 PLXNB1	6.29e-05	819	79	12	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	ARHGEF28 PSEN1 ANK3 SKOR2 TET1 CAPRIN2 DOCK10 LGR4 SPG11 CAPRIN1 ZEB2 PLXNB1	6.82e-05	826	79	12	GO:0048858
MousePheno	decreased cranium width	TBX15 RAF1 DYM	1.61e-05	11	66	3	MP:0008526
MousePheno	prenatal growth retardation	RAF1 RGL1 MYL2 TENM4 PSEN1 BRCA2 TET1 LGR4 ZMYM2 PLCG1 WDFY3 COPS5 STAT3 ARID3B	4.32e-05	869	66	14	MP:0010865
Domain	DUF3504	ZMYM2 QRICH1 ZMYM4	6.97e-07	5	78	3	IPR021893
Domain	DUF3504	ZMYM2 QRICH1 ZMYM4	6.97e-07	5	78	3	PF12012
Domain	Caprin	CAPRIN2 CAPRIN1	1.72e-05	2	78	2	IPR028816
Domain	Caprin-1_C	CAPRIN2 CAPRIN1	1.72e-05	2	78	2	PF12287
Domain	FAM21	WASHC2C WASHC2A	1.72e-05	2	78	2	IPR027308
Domain	Caprin-1_C	CAPRIN2 CAPRIN1	1.72e-05	2	78	2	IPR022070
Domain	FAM21/CAPZIP	WASHC2C WASHC2A	5.15e-05	3	78	2	IPR029341
Domain	CAP-ZIP_m	WASHC2C WASHC2A	5.15e-05	3	78	2	PF15255
Domain	PH_dom-like	ARHGEF28 OSBPL6 DOCK10 PLCG1 BBS5 WDFY3 ARHGEF4 ACAP2 PPP4R3A	6.96e-05	426	78	9	IPR011993
Domain	-	ARHGEF28 OSBPL6 DOCK10 PLCG1 BBS5 ARHGEF4 ACAP2 PPP4R3A	2.24e-04	391	78	8	2.30.29.30
Domain	Znf_MYM	ZMYM2 ZMYM4	3.57e-04	7	78	2	IPR010507
Domain	zf-FCS	ZMYM2 ZMYM4	3.57e-04	7	78	2	PF06467
Domain	TRASH_dom	ZMYM2 ZMYM4	4.74e-04	8	78	2	IPR011017
Domain	TRASH	ZMYM2 ZMYM4	4.74e-04	8	78	2	SM00746
Domain	ZU5	ANK2 ANK3	6.08e-04	9	78	2	SM00218
Domain	ZU5	ANK2 ANK3	7.58e-04	10	78	2	PS51145
Domain	ARM-like	AP2A1 DOCK10 WDFY3 XPO1 PPP4R3A PPP6R3	9.29e-04	270	78	6	IPR011989
Domain	PH	ARHGEF28 OSBPL6 DOCK10 PLCG1 ARHGEF4 ACAP2	1.08e-03	278	78	6	SM00233
Domain	PH_DOMAIN	ARHGEF28 OSBPL6 DOCK10 PLCG1 ARHGEF4 ACAP2	1.10e-03	279	78	6	PS50003
Domain	ZU5	ANK2 ANK3	1.11e-03	12	78	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	1.11e-03	12	78	2	IPR000906
Domain	PH_domain	ARHGEF28 OSBPL6 DOCK10 PLCG1 ARHGEF4 ACAP2	1.12e-03	280	78	6	IPR001849
Domain	Ras_G-nucl-exch_fac_CS	RGL1 RALGDS	1.52e-03	14	78	2	IPR019804
Domain	PH	OSBPL6 DOCK10 PLCG1 ARHGEF4 ACAP2	2.71e-03	229	78	5	PF00169
Domain	BAR	AMPH ACAP2	2.81e-03	19	78	2	PS51021
Domain	ARM-type_fold	AP2A1 TAF2 WDFY3 XPO1 PPP4R3A PPP6R3	2.93e-03	339	78	6	IPR016024
Domain	RasGEFN	RGL1 RALGDS	3.12e-03	20	78	2	SM00229
Domain	RasGEF_N	RGL1 RALGDS	3.43e-03	21	78	2	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RGL1 RALGDS	3.77e-03	22	78	2	IPR000651
Domain	RASGEF_NTER	RGL1 RALGDS	3.77e-03	22	78	2	PS50212
Domain	RASGEF	RGL1 RALGDS	5.24e-03	26	78	2	PS00720
Domain	DEATH	ANK2 ANK3	5.65e-03	27	78	2	SM00005
Domain	RASGEF_CAT	RGL1 RALGDS	6.50e-03	29	78	2	PS50009
Domain	-	AMPH ACAP2	6.94e-03	30	78	2	1.20.1270.60
Domain	RasGEF	RGL1 RALGDS	6.94e-03	30	78	2	PF00617
Domain	-	RGL1 RALGDS	6.94e-03	30	78	2	1.10.840.10
Domain	Ras_GEF_dom	RGL1 RALGDS	6.94e-03	30	78	2	IPR023578
Domain	RASGEF_cat_dom	RGL1 RALGDS	6.94e-03	30	78	2	IPR001895
Domain	AH/BAR-dom	AMPH ACAP2	6.94e-03	30	78	2	IPR027267
Domain	RasGEF	RGL1 RALGDS	6.94e-03	30	78	2	SM00147
Domain	-	ANK2 ANK3 QRICH1	6.94e-03	93	78	3	1.10.533.10
Domain	RA	RGL1 RALGDS	7.40e-03	31	78	2	SM00314
Domain	DEATH-like_dom	ANK2 ANK3 QRICH1	8.25e-03	99	78	3	IPR011029
Pathway	REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE	CPSF6 ZMYM2 PLCG1 STAT3	1.49e-05	38	56	4	M27536
Pathway	REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS	CPSF6 ZMYM2 STAT3	4.64e-05	18	56	3	M673
Pathway	REACTOME_SIGNALING_BY_FGFR_IN_DISEASE	CPSF6 ZMYM2 PLCG1 STAT3	1.12e-04	63	56	4	M635
Pathway	BIOCARTA_TPO_PATHWAY	RAF1 PLCG1 STAT3	1.13e-04	24	56	3	M11520
Pathway	BIOCARTA_TPO_PATHWAY	RAF1 PLCG1 STAT3	1.28e-04	25	56	3	MM1519
Pathway	BIOCARTA_EGF_PATHWAY	RAF1 PLCG1 STAT3	1.62e-04	27	56	3	M1909
Pathway	KEGG_PANCREATIC_CANCER	RAF1 RALGDS BRCA2 STAT3	1.69e-04	70	56	4	M9726
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	RAF1 KMT2D PSEN1 TET1 ZMYM2 STAT3 ARID3B	1.79e-04	301	56	7	MM15983
Pathway	BIOCARTA_EGF_PATHWAY	RAF1 PLCG1 STAT3	1.81e-04	28	56	3	MM1386
Pathway	BIOCARTA_PDGF_PATHWAY	RAF1 PLCG1 STAT3	1.81e-04	28	56	3	M2529
Pathway	BIOCARTA_BIOPEPTIDES_PATHWAY	RAF1 PLCG1 STAT3	2.02e-04	29	56	3	MM1356
Pathway	BIOCARTA_PDGF_PATHWAY	RAF1 PLCG1 STAT3	2.02e-04	29	56	3	MM1452
Pathway	BIOCARTA_BIOPEPTIDES_PATHWAY	RAF1 PLCG1 STAT3	2.02e-04	29	56	3	M13494
Pathway	WP_PDGFRBETA_PATHWAY	RAF1 PLCG1 STAT3	2.02e-04	29	56	3	M39616
Pathway	REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION	CPSF6 ZMYM2 STAT3	2.47e-04	31	56	3	M661
Pathway	WP_PANCREATIC_ADENOCARCINOMA_PATHWAY	RAF1 RALGDS BRCA2 STAT3	4.24e-04	89	56	4	M39732
Pathway	WP_EGFEGFR_SIGNALING	RAF1 RALGDS AP2A1 PLCG1 STAT3	4.48e-04	162	56	5	M39334
Pathway	WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION	AP2A1 PLCG1 STAT3	4.54e-04	38	56	3	M39854
Pathway	WP_PDGF_PATHWAY	RAF1 PLCG1 STAT3	5.29e-04	40	56	3	M39555
Pubmed	Genomic analysis of mouse retinal development.	RALGDS DYM WASHC2C CGRRF1 CPSF6 WDFY3 MERTK WASHC2A RBM39 ZMYM4 STAT3 PPP4R3A NPAS2	6.47e-07	1006	82	13	15226823
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	WASHC2C KLF10 BRCA2 ZMYM2 QRICH1 CAPRIN1 ZMYM4 STAT3 ARID3B	1.07e-06	444	82	9	34795231
Pubmed	Functional proteomics mapping of a human signaling pathway.	KMT2D KLF10 AP2A1 ANK3 ZMYM2 QRICH1 MERTK COPS5 ZEB2 ZNF518A	1.33e-06	591	82	10	15231748
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RAF1 AP2A1 ANK3 CPSF6 OSBPL6 ZNF638 UGGT2 BBS5 PAN3 ACAP2 COPS5 EDRF1 PPP4R3A ARID3B	2.39e-06	1321	82	14	27173435
Pubmed	Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.	RAF1 PLCG1 PLXNB1	3.55e-06	13	82	3	19805522
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGDS TET1 CAPRIN2 SPG11 ACAP2 ZMYM4 PLXNB1 IGSF3 PPP6R3	4.46e-06	529	82	9	14621295
Pubmed	Entero-toxigenic Bacteroides fragilis contributes to intestinal barrier injury and colorectal cancer progression by mediating the BFT/STAT3/ZEB2 pathway.	ZEB2 STAT3	5.49e-06	2	82	2	38273425
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	5.49e-06	2	82	2	20827171
Pubmed	Nuclear retention of STAT3 through the coiled-coil domain regulates its activity.	XPO1 STAT3	5.49e-06	2	82	2	16140268
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	5.49e-06	2	82	2	36717248
Pubmed	A role of STAT3 in Rho GTPase-regulated cell migration and proliferation.	ARHGEF28 STAT3	5.49e-06	2	82	2	15705584
Pubmed	XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer.	XPO1 STAT3	5.49e-06	2	82	2	24431073
Pubmed	Nucleocytoplasmic shuttling of persistently activated STAT3.	XPO1 STAT3	5.49e-06	2	82	2	17726064
Pubmed	Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins.	CAPRIN2 CAPRIN1	5.49e-06	2	82	2	14764709
Pubmed	Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning.	MYL2 STAT3	5.49e-06	2	82	2	15306216
Pubmed	Epidermal hyperplasia induced by Raf-MAPK signaling requires Stat3 activation.	RAF1 STAT3	5.49e-06	2	82	2	23870655
Pubmed	Role of melatonin, melatonin receptors and STAT3 in the cardioprotective effect of chronic and moderate consumption of red wine.	MYL2 STAT3	5.49e-06	2	82	2	26296463
Pubmed	RNA granule protein 140 (RNG140), a paralog of RNG105 localized to distinct RNA granules in neuronal dendrites in the adult vertebrate brain.	CAPRIN2 CAPRIN1	5.49e-06	2	82	2	20516077
Pubmed	Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.	PSEN1 ITGAX	5.49e-06	2	82	2	27425031
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	5.49e-06	2	82	2	15847701
Pubmed	A CRM1-mediated nuclear export signal governs cytoplasmic localization of BRCA2 and is essential for centrosomal localization of BRCA2.	BRCA2 XPO1	5.49e-06	2	82	2	18059333
Pubmed	The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis.	MYL2 STAT3	5.49e-06	2	82	2	18567640
Pubmed	Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf-MEK-ERK Pathway.	RAF1 PSEN1	5.49e-06	2	82	2	31941156
Pubmed	Stat3 upregulates leucine-rich repeat-containing g protein-coupled receptor 4 expression in osteosarcoma cells.	LGR4 STAT3	5.49e-06	2	82	2	24455684
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	5.49e-06	2	82	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	5.49e-06	2	82	2	25383926
Pubmed	Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression.	COPS5 STAT3	5.49e-06	2	82	2	27524414
Pubmed	JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells.	COPS5 STAT3	5.49e-06	2	82	2	23911788
Pubmed	The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.	PSEN1 STAT3	5.49e-06	2	82	2	25673868
Pubmed	Human transcription factor protein interaction networks.	KMT2D KLF10 ZNF638 ZMYM2 TAF2 PAN3 SPATA2 WASHC2A CAPRIN1 ZEB2 ZMYM4 STAT3 PPP6R3 ARID3B	5.89e-06	1429	82	14	35140242
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	WASHC2C AP2A1 ZMYM2 XPO1 COPS5 STAT3 PPP4R3A PPP6R3 ARID3B	7.04e-06	560	82	9	35241646
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ANK2 AP2A1 ANK3 ZMYM2 QRICH1 PLCG1 WDFY3 MERTK COPS5 CAPRIN1 ZEB2 ZMYM4 STAT3	9.40e-06	1285	82	13	35914814
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KMT2D CPSF6 ZMYM2 QRICH1 XPO1 COPS5 CAPRIN1 ZEB2 RBM39 ZMYM4 PPP4R3A ARID3B	1.05e-05	1103	82	12	34189442
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	AP2A1 BRCA2 ZMYM2 ZMYM4 ZNF518A ARID3B	1.48e-05	222	82	6	37071664
Pubmed	Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity.	XPO1 STAT3	1.64e-05	3	82	2	20826784
Pubmed	Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.	TET1 STAT3	1.64e-05	3	82	2	29235481
Pubmed	Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity.	TET1 STAT3	1.64e-05	3	82	2	22210859
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	1.64e-05	3	82	2	15611082
Pubmed	A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.	MERTK STAT3	1.64e-05	3	82	2	19667404
Pubmed	Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.	RAF1 MYL2	1.64e-05	3	82	2	28548091
Pubmed	Expression of CXCL6 and BBS5 that may be glaucoma relevant genes is regulated by PITX2.	PITX2 BBS5	1.64e-05	3	82	2	27520585
Pubmed	Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain.	AMPH AP2A1	1.64e-05	3	82	2	9259551
Pubmed	RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status.	RAF1 STAT3	1.64e-05	3	82	2	37020037
Pubmed	Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins.	ZMYM2 ZMYM4	1.64e-05	3	82	2	32439918
Pubmed	The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice.	COPS5 STAT3	1.64e-05	3	82	2	27693579
Pubmed	Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells.	COPS5 STAT3	1.64e-05	3	82	2	21689417
Pubmed	RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein.	RGL1 RALGDS	1.64e-05	3	82	2	8710374
Pubmed	Enhanced Transcriptional Activity and Mitochondrial Localization of STAT3 Co-induce Axon Regrowth in the Adult Central Nervous System.	COX10 STAT3	1.64e-05	3	82	2	27050520
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	1.64e-05	3	82	2	33410423
Pubmed	[Expression and relationship of p27(kip1) and its related molecules Jab1 and CRM1 during proliferation of lymphoma cells U937].	XPO1 COPS5	1.64e-05	3	82	2	18246793
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	1.64e-05	3	82	2	34289389
Pubmed	Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning.	MYL2 STAT3	1.64e-05	3	82	2	18339648
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAF1 RALGDS ARHGEF28 ANGEL1 DOCK10 ZNF638 UGGT2 DENND5A PLXNB1	2.29e-05	650	82	9	38777146
Pubmed	Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice.	BRCA2 XPO1 PAN3	2.47e-05	24	82	3	26178733
Pubmed	Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors.	RAF1 STAT3	3.28e-05	4	82	2	20469933
Pubmed	RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2‑deficient human acute myeloid leukemia.	BRCA2 STAT3	3.28e-05	4	82	2	32945515
Pubmed	Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis.	AMPH SLC6A5	3.28e-05	4	82	2	25497732
Pubmed	M-Ras, a widely expressed 29-kD homologue of p21 Ras: expression of a constitutively active mutant results in factor-independent growth of an interleukin-3-dependent cell line.	RAF1 RALGDS	3.28e-05	4	82	2	10498616
Pubmed	Ras classical effectors: new tales from in silico complexes.	RAF1 RALGDS	3.28e-05	4	82	2	19801192
Pubmed	Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation.	LGR4 CAT	3.28e-05	4	82	2	25811370
Pubmed	Shikonin-mediated PD-L1 degradation suppresses immune evasion in pancreatic cancer by inhibiting NF-κB/STAT3 and NF-κB/CSN5 signaling pathways.	COPS5 STAT3	3.28e-05	4	82	2	33707115
Pubmed	Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.	PSEN1 COPS5	3.28e-05	4	82	2	35269588
Pubmed	Expression of Jun activation domain-binding protein 1 and Ser10 phosphorylated p27 protein in human epithelial ovarian carcinoma.	XPO1 COPS5	3.28e-05	4	82	2	19139918
Pubmed	Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway.	MYL2 STAT3	3.28e-05	4	82	2	19666677
Pubmed	MerTK mediates STAT3-KRAS/SRC-signaling axis for glioma stem cell maintenance.	MERTK STAT3	3.28e-05	4	82	2	29553850
Pubmed	NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.	BRCA2 TET1 ARID3B	3.55e-05	27	82	3	23395962
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	RALGDS DYM TENM4 TET1 LGR4 QRICH1 WDFY3 STAT3	3.96e-05	536	82	8	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	RALGDS DYM TENM4 TET1 LGR4 QRICH1 WDFY3 STAT3	4.07e-05	538	82	8	10512203
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2D ANK3 TET1 TAF2 ZMYM4 STAT3 PPP6R3 ARID3B	4.69e-05	549	82	8	38280479
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	WASHC2C ANK3 CPSF6 TET1 ANGEL1 ZNF638 LGR4 PLCG1 PAN3 WASHC2A PLXNB1	4.75e-05	1084	82	11	11544199
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TENM4 WASHC2C DOCK10 ARHGEF4 SPATA2 WASHC2A ZEB2	5.10e-05	407	82	7	12693553
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	5.47e-05	5	82	2	25362471
Pubmed	Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.	ANK3 TET1	5.47e-05	5	82	2	18163421
Pubmed	Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras.	RAF1 RALGDS	5.47e-05	5	82	2	9150145
Pubmed	A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization.	BRCA2 XPO1	5.47e-05	5	82	2	24013206
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	5.47e-05	5	82	2	19109891
Pubmed	Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II.	MYL2 PITX2	5.47e-05	5	82	2	10220415
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	5.47e-05	5	82	2	25950943
Pubmed	Nef as a Proliferative Factor for Kidney Epithelial Cells in HIV-Associated Nephropathy.	RAF1 STAT3	5.47e-05	5	82	2	21892329
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ARHGEF28 AP2A1 DOCK10 ZMYM2 CAT ARHGEF4 XPO1 RBM39 PPP6R3 ARID3B	5.90e-05	916	82	10	32203420
Pubmed	Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.	NETO2 ZEB2 IGSF3	5.96e-05	32	82	3	16516881
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAF1 KMT2D BRCA2 TET1 ZMYM2 ZEB2 ZMYM4	6.03e-05	418	82	7	34709266
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	WASHC2C ANK2 CPSF6 ZNF638 ZMYM2 PLCG1 RBM39 STAT3 PPP4R3A PPP6R3	6.93e-05	934	82	10	33916271
Pubmed	Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.	MYL2 PITX2	8.19e-05	6	82	2	10500184
Pubmed	Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway.	COPS5 STAT3	8.19e-05	6	82	2	31802034
Pubmed	Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart.	MYL2 PITX2	8.19e-05	6	82	2	11090542
Pubmed	Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development.	MYL2 PITX2	8.19e-05	6	82	2	31678627
Pubmed	Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo.	RAF1 PLCG1	8.19e-05	6	82	2	8084603
Pubmed	Chimeric analysis of retinoic acid receptor function during cardiac looping.	MYL2 PITX2	8.19e-05	6	82	2	12074552
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	8.19e-05	6	82	2	23728480
Pubmed	Integrated RAS signaling defined by parallel NMR detection of effectors and regulators.	RGL1 RALGDS	8.19e-05	6	82	2	24441586
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ANK3 CPSF6 ANGEL1 PKLR ZNF638 LGR4 SPATA2 IGSF3 ARID3B	9.06e-05	777	82	9	35844135
Pubmed	Clathrin interacts specifically with amphiphysin and is displaced by dynamin.	AMPH AP2A1	1.14e-04	7	82	2	9280305
Pubmed	Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation.	RAF1 RALGDS	1.14e-04	7	82	2	11788587
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	1.14e-04	7	82	2	7495297
Pubmed	Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.	RAF1 RALGDS	1.14e-04	7	82	2	9564038
Pubmed	The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin.	RAF1 RALGDS	1.14e-04	7	82	2	10922060
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	AP2A1 ZMYM2 CAT DTX3L TAF2 XPO1 ZMYM4 STAT3 IGSF3 ZNF518A PPP6R3	1.20e-04	1203	82	11	29180619
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TBX15 KLF10 PITX2 ZNF638 ZMYM2 PLCG1 STAT3 ARID3B NPAS2	1.22e-04	808	82	9	20412781
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KMT2D CPSF6 ZNF638 TAF2 ZEB2 ZMYM4 ARID3B	1.23e-04	469	82	7	27634302
Interaction	MLF1 interactions	PSEN1 BRCA2 MRAP2 WASHC2A EDRF1 PPP6R3	5.83e-06	113	80	6	int:MLF1
Interaction	HOXB2 interactions	KMT2D ZEB2 ZNF518A ARID3B	1.23e-05	36	80	4	int:HOXB2
Interaction	AAGAB interactions	AMPH AP2A1 XPO1 EDRF1	1.38e-05	37	80	4	int:AAGAB
Interaction	HDAC1 interactions	RAF1 KMT2D BRCA2 TET1 PITX2 ZNF638 ZMYM2 XPO1 COPS5 CAPRIN1 ZEB2 RBM39 STAT3 PPP4R3A PPP6R3	2.64e-05	1108	80	15	int:HDAC1
Interaction	WASHC5 interactions	RAF1 WASHC2C XPO1 WASHC2A PPP6R3	2.93e-05	90	80	5	int:WASHC5
Interaction	RBM25 interactions	RAF1 CPSF6 LGR4 TAF2 CAPRIN1 RBM39 PPP4R3A NPAS2	4.25e-05	323	80	8	int:RBM25
Interaction	AP1B1 interactions	RAF1 AMPH AP2A1 XPO1 TSGA10IP COPS5 PPP6R3	4.36e-05	237	80	7	int:AP1B1
Interaction	MRAS interactions	RAF1 RALGDS PKLR	4.71e-05	18	80	3	int:MRAS
Interaction	CIPC interactions	COPS5 ZMYM4 NPAS2	4.71e-05	18	80	3	int:CIPC
Interaction	KLF8 interactions	KMT2D ZNF638 ZMYM2 TAF2 XPO1 CAPRIN1 ZEB2 ZMYM4	4.84e-05	329	80	8	int:KLF8
Interaction	PPIL4 interactions	RAF1 CPSF6 TAF2 ARHGEF4 XPO1 RBM39	5.01e-05	165	80	6	int:PPIL4
Interaction	AGL interactions	RAF1 LGR4 CAT COPS5 SULT1E1	5.35e-05	102	80	5	int:AGL
Interaction	SRRT interactions	RAF1 CPSF6 LGR4 XPO1 RBM39 STAT3 PPP4R3A PPP6R3	6.09e-05	340	80	8	int:SRRT
Interaction	PQBP1 interactions	RAF1 ANK3 CPSF6 CAPRIN1 RBM39	6.15e-05	105	80	5	int:PQBP1
Interaction	IRF5 interactions	XPO1 WASHC2A COPS5 PPP6R3	6.26e-05	54	80	4	int:IRF5
Interaction	DOCK7 interactions	RAF1 ANK3 LGR4 PLCG1 XPO1 WASHC2A COPS5	6.75e-05	254	80	7	int:DOCK7
Interaction	WDHD1 interactions	BRCA2 NETO2 XPO1 CA10 CAPRIN1 PPP4R3A	7.40e-05	177	80	6	int:WDHD1
Interaction	LRPAP1 interactions	RAF1 RALGDS AP2A1 CPSF6 TAF2 CAPRIN1	8.12e-05	180	80	6	int:LRPAP1
Interaction	ROCK2 interactions	RAF1 MYL2 WASHC2C BRCA2 PLCG1 WASHC2A	8.63e-05	182	80	6	int:ROCK2
Interaction	RAPGEF5 interactions	ARHGEF28 ANK2 ANK3 PLCG1	9.48e-05	60	80	4	int:RAPGEF5
Interaction	HNF4A interactions	KMT2D ZMYM2 XPO1 COPS5 ZEB2 ZMYM4 ARID3B	1.11e-04	275	80	7	int:HNF4A
Interaction	KHDRBS1 interactions	AMPH CPSF6 LGR4 PLCG1 ARHGEF4 RBM39 STAT3 PPP6R3	1.16e-04	373	80	8	int:KHDRBS1
Interaction	TNRC6B interactions	RAF1 AP2A1 PAN3 SPATA2 COPS5 CAPRIN1 EDRF1	1.30e-04	282	80	7	int:TNRC6B
Interaction	TNIK interactions	RAF1 ANK2 AP2A1 ANK3 ZMYM2 XPO1 CAPRIN1 ZEB2	1.34e-04	381	80	8	int:TNIK
Interaction	SCAF11 interactions	RAF1 PSEN1 CPSF6 LGR4 STAT3	1.81e-04	132	80	5	int:SCAF11
Interaction	UBAP2L interactions	RAF1 CPSF6 XPO1 PAN3 COPS5 CAPRIN1 RBM39	1.82e-04	298	80	7	int:UBAP2L
Interaction	DEK interactions	RAF1 AP2A1 XPO1 COPS5 CAPRIN1 PPP4R3A	1.84e-04	209	80	6	int:DEK
Interaction	CYP51A1 interactions	RAF1 PSEN1 PTCHD3 CGRRF1 LGR4	1.94e-04	134	80	5	int:CYP51A1
Interaction	WDR82 interactions	RAF1 KMT2D CPSF6 TAF2 XPO1 RBM39	2.04e-04	213	80	6	int:WDR82
Cytoband	10q21	ANK3 TET1	3.72e-04	16	82	2	10q21
Cytoband	1p13	OVGP1 IGSF3	4.21e-04	17	82	2	1p13
Cytoband	10q24.1	ZNF518A CC2D2B	7.11e-04	22	82	2	10q24.1
Cytoband	18q21.1	DYM SKOR2	2.12e-03	38	82	2	18q21.1
GeneFamily	Zinc fingers MYM-type	ZMYM2 ZMYM4	1.30e-04	6	54	2	86
GeneFamily	WASH complex	WASHC2C WASHC2A	1.30e-04	6	54	2	1331
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RGL1 DPYD AMPH KLF10 BRCA2 ZNF638 ZMYM2 SPG11 WDFY3 XPO1 DENND5A ACAP2 ZEB2 RBM39 ZMYM4	4.17e-08	856	80	15	M4500
Coexpression	GABRIELY_MIR21_TARGETS	TET1 DOCK10 ZMYM2 SPG11 PAN3 ACAP2 CAPRIN1 STAT3	2.89e-06	289	80	8	M2196
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN	TBX15 ANK2 CGRRF1 PITX2 DOCK10 PLCG1 WDFY3 CAPRIN1 STAT3	7.61e-06	438	80	9	M227
Coexpression	TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL	RGL1 RALGDS DPYD PSEN1 KLF10 DOCK10 WDFY3 DENND5A ITGAX ZEB2 STAT3	1.23e-05	724	80	11	M41700
Coexpression	GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	NETO2 TET1 BBS5 TAF2 CAPRIN1 ZMYM4	3.25e-05	198	80	6	M9163
Coexpression	GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN	RGL1 DPYD KLF10 ZMYM2 WDFY3 DENND5A	3.44e-05	200	80	6	M9411
Coexpression	GSE19512_NAUTRAL_VS_INDUCED_TREG_DN	RGL1 RALGDS MAN2B2 PSEN1 DENND5A SPATA2	3.44e-05	200	80	6	M8359
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP	RAF1 MAN2B2 ZMYM2 CAT TAF2 STAT3	3.44e-05	200	80	6	M6090
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_0DY_NEGATIVE	DYM WASHC2C KLF10 NETO2 LGR4 UGGT2 DENND5A WASHC2A	5.51e-05	435	80	8	M41115
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	ANK2 ANK3 ZMYM2 CAT WDFY3 XPO1 COPS5 ZEB2 STAT3	5.85e-05	568	80	9	M4023
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	DPYD KLF10 ZNF638 ZMYM2 XPO1 DENND5A RBM39 ZMYM4	8.89e-05	466	80	8	M13522
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE	RAF1 DYM WASHC2C P2RX1 KLF10 AP2A1 NETO2 LGR4 UGGT2 CAT MERTK WASHC2A ITGAX	9.95e-05	1250	80	13	M41099
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	RGL1 DPYD ANK3 NETO2 CPSF6 TET1 DOCK10 LGR4 UGGT2 XPO1 NXT2 NPAS2 SULT1E1	7.12e-06	819	77	13	gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	RGL1 TENM4 ANK2 ANK3 PROKR2 UPK1B PITX2 DTX3L CAPRIN1 ZEB2 ZMYM4 IGSF3	3.62e-05	818	77	12	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	RGL1 KMT2D CAPRIN2 OSBPL6 COX10 ZMYM4 PPP4R3A	3.69e-08	176	82	7	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	DPYD DYM ARHGEF28 ANK3 WDFY3 PAN3 PPP6R3	8.56e-08	199	82	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYD P2RX1 DOCK10 MERTK ITGAX ZEB2	1.68e-06	196	82	6	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RGL1 DPYD DOCK10 MERTK ITGAX ZEB2	1.68e-06	196	82	6	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 DPYD DOCK10 MERTK ITGAX ZEB2	1.73e-06	197	82	6	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DPYD P2RX1 KLF10 WDFY3 ITGAX ZEB2	1.79e-06	198	82	6	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYD AMPH P2RX1 MERTK ITGAX ZEB2	1.89e-06	200	82	6	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	Severe-B_intermediate-14\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 DENND5A NXT2 ZEB2	6.55e-06	142	82	5	f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCell	Control-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 MRAP2 ITGAX ZEB2	1.24e-05	162	82	5	aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 NUP210L IGSF3 NPAS2 SULT1E1	1.52e-05	169	82	5	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD ARHGEF28 ANK3 CAPRIN2 PLXNB1	2.29e-05	184	82	5	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYD ARHGEF28 ANK3 CAPRIN2 PLXNB1	2.29e-05	184	82	5	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	P2RX1 OSBPL6 DOCK10 ITGAX ZEB2	2.60e-05	189	82	5	7ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	P2RX1 OSBPL6 DOCK10 ITGAX ZEB2	2.74e-05	191	82	5	468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 DOCK10 MERTK ITGAX ZEB2	2.81e-05	192	82	5	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	RGL1 DPYD BRCA2 MERTK ZEB2	2.81e-05	192	82	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 DOCK10 MERTK ITGAX ZEB2	2.81e-05	192	82	5	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DPYD DENND5A PAN3 ZEB2 PPP6R3	2.88e-05	193	82	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	RGL1 WASHC2C MERTK ITGAX ZEB2	2.88e-05	193	82	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	DPYD DOCK10 MERTK ITGAX ZEB2	2.88e-05	193	82	5	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARHGEF28 CPSF6 ZNF638 RBM39 PPP6R3	2.88e-05	193	82	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	DPYD MERTK WASHC2A ITGAX ZEB2	2.95e-05	194	82	5	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	RGL1 DPYD BRCA2 MERTK ZEB2	2.95e-05	194	82	5	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 DPYD MERTK ITGAX ZEB2	2.95e-05	194	82	5	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	DPYD DOCK10 MERTK ITGAX ZEB2	2.95e-05	194	82	5	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	RGL1 DPYD MERTK ITGAX ZEB2	3.02e-05	195	82	5	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RGL1 AMPH MERTK ITGAX ZEB2	3.02e-05	195	82	5	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	RGL1 DOCK10 MERTK ITGAX ZEB2	3.02e-05	195	82	5	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYD AMPH KLF10 MERTK ZEB2	3.02e-05	195	82	5	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	RGL1 DPYD BRCA2 MERTK ZEB2	3.02e-05	195	82	5	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NETO2 PKLR DOCK10 ITGAX NXT2	3.10e-05	196	82	5	b71d711be5609115b00a57700885aca608920896
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	RGL1 DPYD MERTK ITGAX ZEB2	3.10e-05	196	82	5	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	RGL1 DOCK10 MERTK ITGAX ZEB2	3.10e-05	196	82	5	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RGL1 DOCK10 MERTK ITGAX ZEB2	3.10e-05	196	82	5	1b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPYD DOCK10 MERTK ITGAX ZEB2	3.18e-05	197	82	5	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPYD DOCK10 MERTK ITGAX ZEB2	3.18e-05	197	82	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	DPYD P2RX1 DOCK10 ITGAX ZEB2	3.18e-05	197	82	5	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD DOCK10 MERTK ITGAX ZEB2	3.18e-05	197	82	5	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TENM4 LGR4 ARHGEF4 NPAS2 SULT1E1	3.18e-05	197	82	5	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPYD P2RX1 DOCK10 ITGAX ZEB2	3.25e-05	198	82	5	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	RGL1 DPYD MERTK ITGAX ZEB2	3.25e-05	198	82	5	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF10 QRICH1 PAN3 CAPRIN1 PPP4R3A	3.25e-05	198	82	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DPYD KLF10 WDFY3 ITGAX ZEB2	3.25e-05	198	82	5	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P2RX1 OSBPL6 DOCK10 ITGAX ZEB2	3.25e-05	198	82	5	cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF10 QRICH1 PAN3 CAPRIN1 PPP4R3A	3.25e-05	198	82	5	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P2RX1 OSBPL6 DOCK10 ITGAX ZEB2	3.25e-05	198	82	5	d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF10 QRICH1 PAN3 CAPRIN1 PPP4R3A	3.25e-05	198	82	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF10 QRICH1 PAN3 CAPRIN1 PPP4R3A	3.33e-05	199	82	5	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	RGL1 DPYD MERTK ITGAX ZEB2	3.33e-05	199	82	5	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RGL1 WDFY3 MERTK ITGAX ZEB2	3.33e-05	199	82	5	0f3ce61bbae69f7e333ed8dacf7257645624e163
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DPYD KLF10 WDFY3 ITGAX ZEB2	3.41e-05	200	82	5	934c2efc780318c66d667ca75be0de350361d351
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TENM4 LGR4 ARHGEF4 NPAS2 SULT1E1	3.41e-05	200	82	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ANK2 ANK3 NETO2 ZEB2 IGSF3	3.41e-05	200	82	5	5b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DPYD PSEN1 ANK3 DOCK10 ZEB2	3.41e-05	200	82	5	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	Mild/Remission-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 ITGAX ZEB2	1.16e-04	136	82	4	1b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCell	Severe-B_intermediate-14\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DYM ANK2 ANK3 NXT2	1.37e-04	142	82	4	9c7d5783302974b883bd887f997d094eb5925ec2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RGL1 P2RX1 WDFY3 IGSF3	1.61e-04	148	82	4	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	RGL1 BBS5 WDFY3 MERTK	1.97e-04	156	82	4	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	P2RX1 NUP210L DOCK10 ZEB2	2.17e-04	160	82	4	6ed37d1fd0304932319d6b942502404115ff36a7
ToppCell	lymphoid-T_cell-pro-T_cell\|T_cell / Lineage, cell class and subclass	MYL2 P2RX1 ITGAX ZEB2	2.17e-04	160	82	4	66fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	TET1 ANGEL1 PLXNB1 ARID3B	2.67e-04	169	82	4	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	P2RX1 DOCK10 ITGAX ZEB2	2.86e-04	172	82	4	c477008444d2d71071177807870d7455e90c2fad
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ITGAX ZEB2 ARID3B	2.86e-04	172	82	4	72fbfa890995e47048b47199c170cc7dcd7661f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 ITGAX ZEB2 ARID3B	2.86e-04	172	82	4	2ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGL1 DPYD WDFY3 ITGAX	2.86e-04	172	82	4	7295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AMPH ANK3 LGR4 IGSF3	2.92e-04	173	82	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-7\|TCGA-Thryoid / Sample_Type by Project: Shred V9	ARHGEF28 NETO2 OSBPL6 COX10	3.12e-04	176	82	4	9a4cef3dc88f64a71b91ab4790ea19334afee3ee
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 NUP210L IGSF3 SULT1E1	3.12e-04	176	82	4	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 NUP210L IGSF3 SULT1E1	3.12e-04	176	82	4	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	COVID-19-lung-MAST\|COVID-19 / Disease (COVID-19 only), tissue and cell type	P2RX1 DOCK10 ITGAX ZEB2	3.12e-04	176	82	4	473c45a381ca109207d66ed1635668b391ea0e1f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 ANK2 XPO1 CA10	3.26e-04	178	82	4	dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGL1 WDFY3 MERTK ITGAX	3.26e-04	178	82	4	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	RGL1 WDFY3 MERTK ITGAX	3.40e-04	180	82	4	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 TET1 DOCK10 NPAS2	3.40e-04	180	82	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYD P2RX1 ITGAX ZEB2	3.47e-04	181	82	4	8657d35cd3dff6c89d0fde67d7e7e81e1d6c8884
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 MERTK ITGAX ZEB2	3.54e-04	182	82	4	ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	ARHGEF28 LGR4 ARHGEF4 NPAS2	3.62e-04	183	82	4	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	WASHC2C DTX3L WASHC2A PPP4R3A	3.62e-04	183	82	4	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 ITGAX ZEB2	3.62e-04	183	82	4	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPYD ANK3 CAPRIN2 PLXNB1	3.69e-04	184	82	4	204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	TENM4 MRAP2 ACAP2 IGSF3	3.69e-04	184	82	4	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RALGDS DOCK10 MERTK ITGAX	3.69e-04	184	82	4	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPYD ANK3 CAPRIN2 PLXNB1	3.69e-04	184	82	4	9365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	ARHGEF28 LGR4 ARHGEF4 NPAS2	3.69e-04	184	82	4	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PROKR2 NETO2 DOCK10 IGSF3	3.77e-04	185	82	4	caf4f57f2db9ff72a652c8573e16e7ab180ffc05
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KMT2D DOCK10 XPO1 ZEB2	3.77e-04	185	82	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	RGL1 WDFY3 MERTK ZEB2	3.77e-04	185	82	4	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 TENM4 ANK3 CAT	3.77e-04	185	82	4	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYD ANK2 DOCK10 ZEB2	3.77e-04	185	82	4	0149981d3818a6250f32c08456c28e7037c39d91
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	RALGDS DOCK10 MERTK ITGAX	3.85e-04	186	82	4	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RALGDS DOCK10 MERTK ITGAX	3.85e-04	186	82	4	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	NS-moderate-d_0-4-Myeloid-Non-resident_Macrophage\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	P2RX1 DOCK10 ITGAX ZEB2	3.92e-04	187	82	4	fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 LGR4 MERTK CA10	3.92e-04	187	82	4	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ARHGEF28 ZNF638 LGR4 SULT1E1	3.92e-04	187	82	4	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 ANK3 LGR4 CA10	3.92e-04	187	82	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
Disease	Malignant neoplasm of breast	RAF1 RGL1 DPYD KMT2D ANK2 BRCA2 UPK1B SLC6A5 CAT DTX3L ARHGEF4 ZEB2 PLXNB1 STAT3	1.06e-06	1074	80	14	C0006142
Disease	Cardiomyopathies	RAF1 MYL2 PSEN1 CAT STAT3	2.83e-05	130	80	5	C0878544
Disease	Partial Fetal Alcohol Syndrome	ANK3 CAT	7.22e-05	5	80	2	C3661483
Disease	Alcohol Related Neurodevelopmental Disorder	ANK3 CAT	7.22e-05	5	80	2	C0814154
Disease	Mammary Carcinoma, Human	RAF1 DPYD KMT2D BRCA2 UPK1B CAT ZEB2 STAT3	8.98e-05	525	80	8	C4704874
Disease	Mammary Neoplasms, Human	RAF1 DPYD KMT2D BRCA2 UPK1B CAT ZEB2 STAT3	8.98e-05	525	80	8	C1257931
Disease	Mammary Neoplasms	RAF1 DPYD KMT2D BRCA2 UPK1B CAT ZEB2 STAT3	9.22e-05	527	80	8	C1458155
Disease	Breast Carcinoma	RAF1 DPYD KMT2D BRCA2 UPK1B CAT ZEB2 STAT3	1.06e-04	538	80	8	C0678222
Disease	Asphyxia Neonatorum	PSEN1 CAT	1.08e-04	6	80	2	C0004045
Disease	Alcohol Related Birth Defect	ANK3 CAT	1.08e-04	6	80	2	C3146244
Disease	colorectal carcinoma (biomarker_via_orthology)	CAT STAT3	2.01e-04	8	80	2	DOID:0080199 (biomarker_via_orthology)
Disease	eye morphology measurement	TBX15 WASHC2C CGRRF1 CAPRIN2 CA10	3.22e-04	218	80	5	EFO_0007858
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D XPO1	3.93e-04	11	80	2	DOID:3717 (is_implicated_in)
Disease	diastolic blood pressure, systolic blood pressure	TBX15 RGL1 TENM4 ANK2 ANK3 OSBPL6 TAF2 NPAS2	4.67e-04	670	80	8	EFO_0006335, EFO_0006336
Disease	Pulmonary Thromboembolisms	CAT MERTK	4.71e-04	12	80	2	C0524702
Disease	Pulmonary Embolism	CAT MERTK	4.71e-04	12	80	2	C0034065
Disease	Hypertrophic Cardiomyopathy	RAF1 MYL2 KLF10	5.05e-04	57	80	3	C0007194
Disease	Fetal Alcohol Spectrum Disorders	ANK3 CAT	5.55e-04	13	80	2	C2985290
Disease	chronotype measurement	RGL1 DPYD KMT2D ANK2 ANK3 SKOR2 TET1 CA10 NPAS2	6.36e-04	882	80	9	EFO_0008328
Disease	T-Cell Lymphoma	KMT2D STAT3	8.50e-04	16	80	2	C0079772
Disease	Cardiomyopathies, Primary	PSEN1 CAT STAT3	8.84e-04	69	80	3	C0033141
Disease	Myocardial Diseases, Secondary	PSEN1 CAT STAT3	8.84e-04	69	80	3	C0036529
Disease	Nonorganic psychosis	TENM4 ANK3 TET1	8.84e-04	69	80	3	C0349204
Disease	Malignant Glioma	RAF1 BRCA2 CAT	9.22e-04	70	80	3	C0555198
Disease	mixed gliomas	RAF1 BRCA2 CAT	9.22e-04	70	80	3	C0259783
Disease	glaucoma (implicated_via_orthology)	PITX2 LGR4	9.61e-04	17	80	2	DOID:1686 (implicated_via_orthology)
Disease	Fetal Alcohol Syndrome	ANK3 CAT	9.61e-04	17	80	2	C0015923
Disease	laryngeal squamous cell carcinoma (is_marker_for)	CAT PLCG1	1.20e-03	19	80	2	DOID:2876 (is_marker_for)
Disease	Hepatitis, Chronic	CAT STAT3	1.62e-03	22	80	2	C0019189
Disease	Chronic active hepatitis	CAT STAT3	1.62e-03	22	80	2	C0520463
Disease	Chronic Persistent Hepatitis	CAT STAT3	1.62e-03	22	80	2	C0149519
Disease	Cryptogenic Chronic Hepatitis	CAT STAT3	1.62e-03	22	80	2	C0524611
Disease	Glioma	RAF1 BRCA2 CAT	1.73e-03	87	80	3	C0017638
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KMT2D MERTK	1.77e-03	23	80	2	C1708353
Disease	Reperfusion Injury	CAT STAT3 SULT1E1	1.84e-03	89	80	3	C0035126
Disease	Bipolar Disorder	TENM4 ANK3 PROKR2 BRCA2 PLCG1 NPAS2	1.90e-03	477	80	6	C0005586
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	DPYD CA10	1.93e-03	24	80	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	Neurodevelopmental Disorders	ANK2 WDFY3 PLXNB1	2.09e-03	93	80	3	C1535926
Disease	Hypertrophic obstructive cardiomyopathy	RAF1 MYL2	2.09e-03	25	80	2	C4551472
Disease	isthmus cingulate cortex volume measurement	TENM4 PTCHD3	2.26e-03	26	80	2	EFO_0010310
Disease	Sezary Syndrome	KMT2D PLCG1	2.44e-03	27	80	2	C0036920
Disease	Pancreatic Neoplasm	DPYD BRCA2 STAT3	2.57e-03	100	80	3	C0030297
Disease	gastric adenocarcinoma (is_marker_for)	CAT XPO1	2.62e-03	28	80	2	DOID:3717 (is_marker_for)
Disease	Psychotic Disorders	TENM4 ANK3 TET1	2.64e-03	101	80	3	C0033975
Disease	pancreatic cancer (is_marker_for)	DPYD CAT XPO1	2.64e-03	101	80	3	DOID:1793 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAFQRNFFSMARQLP	ARID3B	451	Q8IVW6
DVSTQMLNQQFQEPF	COPS5	151	Q92905
ANMNDSFNVSIPYLQ	BBS5	191	Q8N3I7
IQVMTFNQAETFPFN	CAT	281	P04040
QPQAKSQQRMFFLFD	ARHGEF4	511	Q9NR80
INKFFQPTEMAAQDF	AP2A1	861	O95782
INQFFEVPFDSNMNR	COX10	206	Q12887
QQFATEVFKAMSIPQ	DPYD	156	Q12882
QDIFRDFSQMASNNP	ACAP2	751	Q15057
QQNNTPMAVFFDYSK	CC2D2B	1261	Q6DHV5
INVNAAPFQSMQTVF	CAPRIN1	506	Q14444
NGFTQPQDTSLFTMQ	AMPH	401	P49418
VIRMQDNNPFSFQSD	RAF1	516	P04049
LATQCFQLSNMFNPQ	RBM39	421	Q14498
FQLSNMFNPQTEEEV	RBM39	426	Q14498
VQTLANSLFPAQFMN	QRICH1	376	Q2TAL8
PDSANVFYAMNSQVN	RGL1	711	Q9NZL6
FQRPSTQFSLMQFSN	ITGAX	181	P20702
QPQNRDAFFKTLSNM	PPP4R3A	346	Q6IN85
NVFSMFEQTQIQEFK	MYL2	16	P10916
PMAQFSAQFSMFQTI	NPAS2	491	Q99743
LVQMSFNTFNKLNPS	ARHGEF28	1571	Q8N1W1
QSQNGFTPLYMAAQE	ANK2	126	Q01484
KQPESMNVTRNTAFN	MERTK	201	Q12866
FAEFQMTSQNSNVGK	EDRF1	1086	Q3B7T1
NNLSFMKTNSIPYQN	LRRC53	1016	A6NM62
KNPQFVFDVQTSDNM	PLXNB1	1991	O43157
FQQQQLPAAMADTFL	PKLR	56	P30613
MNNITQLPEDAFKNF	LGR4	66	Q9BXB1
QRTQSAPNFTDMQAN	OSBPL6	286	Q9BZF3
TFDNSQNNNPLALMA	PAN3	666	Q58A45
MEQVQPNSFSLGIFN	IGSF3	486	O75054
QPMAANYNVFLNSSK	GSTT4	176	A0A1W2PR19
VTPCNKQFLSQFEMQ	CPSF6	156	Q16630
FQLTQLPDNSYIMNF	DOCK10	211	Q96BY6
ITPQMLFSKQDFNSN	BRCA2	1086	P51587
QFLESEQKQQFSPSM	DTX3L	191	Q8TDB6
QAIMSFKNTQDSSPF	DYM	306	Q7RTS9
QSQNGFTPLYMAAQE	ANK3	136	Q12955
QMQNFDKASFLSDQP	DENND5A	551	Q6IQ26
NTAPFQAMQTVFNVN	CAPRIN2	756	Q6IMN6
PENANVFYAMNSTAN	RALGDS	861	Q12967
QFFNASVQFANMDPL	MAN2B2	291	Q9Y2E5
PMKAASILNYQNNSF	KLF10	171	Q13118
SQNQPSQIFLSMSDN	CA10	271	Q9NS85
KQLFMSANNNFTPSN	CGRRF1	226	Q99675
NTFMNNIPDFLSNFP	PTCHD3	716	Q3KNS1
VVNFTSFQQMASPVF	NUP210L	1756	Q5VU65
FAFASMNNNQIVAKD	OVGP1	56	Q12889
NFFDTLPSSEFQVNM	NXT2	61	Q9NPJ8
GNNSISFQSFMAQLF	OR4A4P	86	Q8NGN8
VFPAQGDNSFVVMTN	P2RX1	91	P51575
PFLFQQAMQANARLT	TSGA10IP	466	Q3SY00
APLSYFQNAQMSEDN	PSEN1	6	P49768
YPNVTMVNFTSQANK	SLC6A5	351	Q9Y345
SCPNIVKTNNFMSFQ	TAF2	731	Q6P1X5
SFPTSQFQYVMQAGN	TBX15	471	Q96SF7
FRNDFAQPQPMKTFN	NETO2	461	Q8NC67
TKSFPFFNSMNVNPL	PITX2	191	Q99697
FFNSMNVNPLSSQSM	PITX2	196	Q99697
NDYAMNFFTNPTKNL	TET1	1396	Q8NFU7
PQFQFTLMSYNILAQ	ANGEL1	241	Q9UNK9
KQMFNPTEESQTFLQ	SPG11	2071	Q96JI7
FQLCQFVMENSQNAP	XPO1	206	O14980
FMPNNQLNYKSTQLS	SPATA2	501	Q9UM82
ISAMNVFPSNTQPFQ	WDFY3	731	Q8IZQ1
LMKFDIPNFVNTDQN	MRAP2	161	Q96G30
TSFQEMKNNPSTNYT	SULT1E1	226	P49888
SVEPYTKQQLNNMSF	STAT3	636	P40763
MFSDQNFLAQATFPV	PLCG1	1166	P19174
NKPFLNTQNMYELSS	TENM4	1566	Q6N022
NVFNDFLMLSNTQFI	WASHC2C	81	Q9Y4E1
MAAQNGNTSFTPNFN	PROKR2	1	Q8NFJ6
NNKLAVSPNYNATFM	ZNF518A	431	Q6AHZ1
NTSFPVFNNFQDQMK	SKOR2	966	Q2VWA4
TQQDFFTPNLFLKQM	UPK1B	111	O75841
FQALSMQSSPNGQFV	ZMYM2	616	Q9UBW7
NVFNDFLMLSNTQFI	WASHC2A	81	Q641Q2
TNPQENDMFFNVIAI	UGGT2	956	Q9NYU1
DNKSTNPVFSMNPFS	ZEB2	876	O60315
MQQMTSNFIDQFGFN	PPP6R3	551	Q5H9R7
AQSMYSFLKQNPQNI	ZNF638	1056	Q14966
FQNLFNKPTGMNSSV	ZMYM4	611	Q5VZL5
LAMQQQLANSFFPDT	KMT2D	3396	O14686