Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cell projection assembly	CDC42EP4 NUP85 FGD2 IFT81 FBF1 EHD1 IFT122 SCIN MAP4K4 IQUB EVI5L DNM2 DNAH1	7.36e-06	685	89	13	GO:0030031
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	CDC42EP4 NUP85 FGD2 IFT81 FBF1 EHD1 IFT122 MAP4K4 IQUB EVI5L DNM2 DNAH1	3.02e-05	670	89	12	GO:0120031
Domain	Spectrin_repeat	SPTA1 MCF2 MACF1	4.23e-04	29	95	3	IPR002017
Domain	Spectrin/alpha-actinin	SPTA1 MCF2 MACF1	5.68e-04	32	95	3	IPR018159
Domain	SPEC	SPTA1 MCF2 MACF1	5.68e-04	32	95	3	SM00150
Domain	Villin/Gelsolin	FLII SCIN	7.03e-04	8	95	2	IPR007122
Domain	GEL	FLII SCIN	7.03e-04	8	95	2	SM00262
Domain	-	MYL5 TCHHL1 SPTA1 DYTN EHD1 MACF1	2.17e-03	261	95	6	1.10.238.10
Domain	Gelsolin	FLII SCIN	2.24e-03	14	95	2	PF00626
Domain	G_DYNAMIN_dom	EHD1 DNM2	2.24e-03	14	95	2	IPR030381
Domain	Gelsolin-like_dom	FLII SCIN	2.24e-03	14	95	2	IPR007123
Domain	G_DYNAMIN_2	EHD1 DNM2	2.24e-03	14	95	2	PS51718
Domain	-	KDM5C ARID5B	2.57e-03	15	95	2	1.10.150.60
Domain	Dynamin_GTPase	EHD1 DNM2	2.57e-03	15	95	2	IPR001401
Domain	BRIGHT	KDM5C ARID5B	2.57e-03	15	95	2	SM00501
Domain	Dynamin_N	EHD1 DNM2	2.57e-03	15	95	2	PF00350
Domain	ARID_dom	KDM5C ARID5B	2.57e-03	15	95	2	IPR001606
Domain	ARID	KDM5C ARID5B	2.57e-03	15	95	2	PS51011
Domain	ARID	KDM5C ARID5B	2.57e-03	15	95	2	PF01388
Domain	Dynamin_SF	EHD1 DNM2	2.57e-03	15	95	2	IPR022812
Domain	EF-hand-dom_pair	MYL5 TCHHL1 SPTA1 DYTN EHD1 MACF1	3.46e-03	287	95	6	IPR011992
Domain	GAGE	PAGE2 PAGE2B	4.14e-03	19	95	2	IPR031320
Domain	GAGE	PAGE2 PAGE2B	4.14e-03	19	95	2	SM01379
Domain	Spectrin	SPTA1 MACF1	6.04e-03	23	95	2	PF00435
Domain	Kinase-like_dom	PI4KA SYK SIK2 MACF1 LCK MAP4K4 MUSK DNM2	6.38e-03	542	95	8	IPR011009
Domain	EF_HAND_2	MYL5 TCHHL1 SPTA1 EHD1 MACF1	6.52e-03	231	95	5	PS50222
Domain	ADF-H/Gelsolin-like_dom	FLII SCIN	6.57e-03	24	95	2	IPR029006
Domain	-	FLII SCIN	6.57e-03	24	95	2	3.40.20.10
Domain	GAGE	PAGE2 PAGE2B	6.57e-03	24	95	2	PF05831
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLII USP13 MAGED1 GAMT TCOF1 IFT81 ARID5B APBB2 MACF1 IFT122 CMYA5 METTL26 MAP4K4 YWHAH CUX1 DNM2 DNMT1	7.94e-08	1285	96	17	35914814
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	A2M USP13 MAGED1 CLCN3 NUP85 UPF2 SIK2 IFT122 QSER1 MAP4K4 DNM2 DNMT1	2.46e-07	650	96	12	38777146
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CLCN3 NUP85 TCHHL1 SPTA1 IFT81 FBF1 MACF1 SMARCD2 BRD3 IFT122 TOP1MT EPX PDIA3 YWHAH PLXNA2 CUX1 TASOR2	4.03e-07	1442	96	17	35575683
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CHMP7 MAGED1 TCOF1 DSG2 PI4KA IFT81 SLMAP SIK2 MACF1 IFT122 MAP4K4 PDIA3 GNL3 CUX1 DNMT1 C19orf25 HDLBP	6.17e-07	1487	96	17	33957083
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDC42EP4 DSG2 PHF3 ATG13 PI4KA SIK2 MACF1 LCK MAP4K4 YWHAH MUSK DNMT1 AHNAK2	7.29e-07	861	96	13	36931259
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLII NUP85 TCOF1 DSG2 PI4KA MKI67 MACF1 RFC2 SCIN MAP4K4 PDIA3 YWHAH GNL3 HDLBP	8.56e-07	1024	96	14	24711643
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	A2M FLII UPF2 TCOF1 DSG2 TCHHL1 PHF3 EHD1 MKI67 SMARCD2 RFC2 MIDEAS PDIA3 GNL3 DNMT1 HDLBP	1.06e-06	1371	96	16	36244648
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FAT4 CDC42EP4 TCOF1 DSG2 PI4KA EHD1 MKI67 APBB2 ARL15 CUX1 TASOR2 DNMT1	1.60e-06	777	96	12	35844135
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	A2M FLII NUP85 UPF2 DSG2 PHF3 SLMAP MKI67 SMARCD2 RFC2 YWHAH GNL3 TASOR2 DNMT1 HDLBP	1.82e-06	1257	96	15	36526897
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	NUP85 TAF9B TCOF1 PI4KA EHD1 MKI67 SMARCD2 QSER1 GNL3	2.11e-06	410	96	9	26949251
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TAF9B TCOF1 DSG2 PHF3 QSER1 MIDEAS MAP4K4 CUX1 DNMT1 HDLBP	2.96e-06	549	96	10	38280479
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLII MAGED1 EIF4ENIF1 UPF2 PHF3 MKI67 PLEKHJ1 MACF1 SMARCD2 AHNAK2 HDLBP	5.23e-06	724	96	11	36232890
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	FLII NUP85 KDM5C MKI67 MSH5 RFC2 TOP1MT	6.31e-06	250	96	7	33536335
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PHF3 MKI67 SMARCD2 BRD3 QSER1 RFC2 MIDEAS GNL3 CUX1 DNMT1	7.26e-06	608	96	10	36089195
Pubmed	DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.	FGF8 DNMT1	7.54e-06	2	96	2	11157065
Pubmed	Functional and behavioral effects of de novo mutations in calcium-related genes in patients with bipolar disorder.	EHD1 MACF1	7.54e-06	2	96	2	34100076
Pubmed	Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis.	SYK LCK	7.54e-06	2	96	2	16474166
Pubmed	Regulation of the Lck SH2 domain by tyrosine phosphorylation.	SYK LCK	7.54e-06	2	96	2	8798764
Pubmed	Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of Lck.	SYK LCK	7.54e-06	2	96	2	8798676
Pubmed	Alpha-1 antichymotrypsin and alpha-2 macroglobulin gene polymorphisms are not associated with Korean late-onset Alzheimer's disease.	A2M SERPINA3	7.54e-06	2	96	2	11290389
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MAGED1 EIF4ENIF1 MKI67 MACF1 MAP4K4 PDIA3 AHNAK2	8.77e-06	263	96	7	34702444
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLII EXO5 TCOF1 PHF3 KDM5C MKI67 BRD3 MAP4K4 DNM2 DNMT1 HDLBP	9.79e-06	774	96	11	15302935
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	A2M ARID5B SIK2 MACF1 LCK MIDEAS GNL3 TASOR2 DNAH1	9.82e-06	496	96	9	31343991
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TAF9B PHF3 ARID5B SMARCD2 QSER1 MIDEAS CUX1	9.91e-06	268	96	7	33640491
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EIF4ENIF1 TAF9B TCOF1 DSG2 KDM5C FBF1 MACF1 SMARCD2 BRD3 RFC2 YWHAH GNL3 EVI5L	1.22e-05	1116	96	13	31753913
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	C14orf93 TAF9B TCOF1 PHF3 SPTA1 ARID5B MKI67 BRD3 QSER1 RFC2 MIDEAS GNL3 CUX1 DNMT1	1.26e-05	1294	96	14	30804502
Pubmed	ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.	FAT2 MKI67 CUX1	1.35e-05	17	96	3	26581405
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TSHZ2 ATG13 ARID5B APBB2 MACF1 KYAT3 IFT122 MSH5 QSER1 ARL15 GNL3 CUX1 EVI5L TASOR2 DNAH1	1.39e-05	1489	96	15	28611215
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	NUP85 TCOF1 EHD1 BRD3 RFC2 MAP4K4 YWHAH GNL3 DNMT1 HDLBP	1.57e-05	665	96	10	30457570
Pubmed	Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.	FAT4 FAT2 MKI67	1.61e-05	18	96	3	33108146
Pubmed	Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression.	SYK LCK	2.26e-05	3	96	2	10453000
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	FLII ARID5B MKI67 RFC2 DNMT1	2.60e-05	125	96	5	21654808
Pubmed	The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions.	SYK LCK MUSK	3.02e-05	22	96	3	24447338
Pubmed	Protective function of the SQSTM1/p62-NEDD4 complex against methylmercury toxicity.	PDIA3 YWHAH	4.51e-05	4	96	2	35452957
Pubmed	Silencing of NRAGE induces autophagy via AMPK/Ulk1/Atg13 signaling pathway in NSCLC cells.	MAGED1 ATG13	4.51e-05	4	96	2	28639909
Pubmed	Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex.	SYK LCK	4.51e-05	4	96	2	7539035
Pubmed	Complex formation between human kallikrein 13 and serum protease inhibitors.	A2M SERPINA3	4.51e-05	4	96	2	14687906
Pubmed	GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders.	MKI67 CUX1	4.51e-05	4	96	2	38019906
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	A2M FLII FAT4 NUP85 TCOF1 PI4KA MKI67 PDIA3 HCCS HDLBP	4.56e-05	754	96	10	35906200
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TCOF1 DSG2 MKI67 MACF1 SCIN PDIA3 GNL3 DNM2 DNMT1 AHNAK2 HDLBP	5.45e-05	934	96	11	33916271
Pubmed	The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.	SERPINA3 SPTA1 LCK	5.68e-05	27	96	3	8390965
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	USP13 USP38 TCOF1 SLMAP MACF1 DNM2 DNMT1 HDLBP	5.78e-05	481	96	8	28190767
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	FLII ST13P4 MAGED1 DSG2 LCK PDIA3 GNL3 TASOR2 HDLBP	5.90e-05	624	96	9	33729478
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CHMP7 FLII EIF4ENIF1 NUP85 UPF2 PI4KA SLMAP PDIA3 HCCS YWHAH GNL3 CUX1 AHNAK2 C19orf25	6.16e-05	1496	96	14	32877691
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	CHMP7 FAT4 EIF4ENIF1 TCOF1 PHF3 MAP4K4	6.42e-05	246	96	6	15345747
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLII TCOF1 DSG2 SLMAP MACF1 DNM2 AHNAK2	6.50e-05	360	96	7	33111431
Pubmed	A protein interaction landscape of breast cancer.	TCOF1 DSG2 PI4KA EHD1 MKI67 MACF1 SMARCD2 DNM2 HDLBP	6.66e-05	634	96	9	34591612
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FLII MAGED1 TCOF1 PI4KA MACF1 QSER1 MAP4K4 YWHAH CUX1 DNM2 DNMT1	7.16e-05	963	96	11	28671696
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	FLII EIF4ENIF1 UPF2 SLMAP MAP4K4 DNM2	7.17e-05	251	96	6	29778605
Pubmed	Human glandular kallikrein, hK2, shows arginine-restricted specificity and forms complexes with plasma protease inhibitors.	A2M SERPINA3	7.50e-05	5	96	2	9428387
Pubmed	Disc1 point mutations in mice affect development of the cerebral cortex.	MKI67 CUX1	7.50e-05	5	96	2	21368031
Pubmed	Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate.	SPTA1 SYK	7.50e-05	5	96	2	23533167
Pubmed	Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase.	PI4KA LCK	7.50e-05	5	96	2	8246987
Pubmed	Selective regulation of Lyn tyrosine kinase by CD45 in immature B cells.	SYK LCK	7.50e-05	5	96	2	7499277
Pubmed	Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan.	A2M SERPINA3	7.50e-05	5	96	2	11099722
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCOF1 PHF3 MKI67 MACF1 GNL3 DNM2 TASOR2 DNMT1 HDLBP	8.33e-05	653	96	9	22586326
Pubmed	A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.	TCOF1 RFC2 DNMT1	8.66e-05	31	96	3	12171929
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLII UPF2 PI4KA EHD1 MKI67 MACF1 RFC2 MIDEAS PDIA3 GNL3 DNMT1 AHNAK2 HDLBP	8.88e-05	1353	96	13	29467282
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	PHF3 MKI67 TASOR2 HDLBP	9.73e-05	86	96	4	37253089
Pubmed	Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.	FBF1 MKI67 CUX1	1.05e-04	33	96	3	30626697
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5C BRD3 DNMT1	1.05e-04	33	96	3	26864203
Pubmed	DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus.	MKI67 DNMT1	1.12e-04	6	96	2	27251626
Pubmed	Lhx9 gene expression during early limb development in mice requires the FGF signalling pathway.	MKI67 FGF8	1.12e-04	6	96	2	26220830
Pubmed	Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.	SYK LCK	1.12e-04	6	96	2	9710204
Pubmed	Joint analysis of candidate genes related to Alzheimer's disease in a Spanish population.	A2M SERPINA3	1.12e-04	6	96	2	12782964
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	USP13 ST13P4 PHF3 KDM5C MKI67 SMARCD2 BRD3 QSER1 RFC2 GNL3 DNMT1	1.13e-04	1014	96	11	32416067
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	FLII TAF9B MKI67 SMARCD2 BRD3 RFC2 GNL3 DNMT1	1.18e-04	533	96	8	30554943
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	ST13P4 UPF2 MACF1 SMARCD2 RFC2 HSP90AA5P MAP4K4 YWHAH DNM2 DNMT1	1.19e-04	847	96	10	35235311
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	FLII ARID5B SMARCD2 BRD3 IFT122 CUX1 DNMT1	1.21e-04	398	96	7	35016035
Pubmed	Identification of the BRD1 interaction network and its impact on mental disorder risk.	QSER1 YWHAH DNMT1	1.25e-04	35	96	3	27142060
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DSG2 ATG13 EHD1 APBB2 PLEKHJ1 SCIN	1.44e-04	285	96	6	34369648
Pubmed	NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.	FGF8 MSH5 DNMT1	1.48e-04	37	96	3	15326356
Pubmed	The functional interactome landscape of the human histone deacetylase family.	NUP85 ARID5B MKI67 MIDEAS PDIA3 YWHAH	1.55e-04	289	96	6	23752268
Pubmed	USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer.	USP13 USP38	1.57e-04	7	96	2	36037364
Pubmed	SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation.	SYK LCK	1.57e-04	7	96	2	10209036
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT4 FAT2	1.57e-04	7	96	2	16059920
Pubmed	Wnt5a is required for cardiac outflow tract septation in mice.	FGF8 PLXNA2	1.57e-04	7	96	2	17515859
Pubmed	Expression analysis of an evolutionarily conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon.	MKI67 CUX1	1.57e-04	7	96	2	20503375
Pubmed	Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling.	SYK LCK	1.57e-04	7	96	2	11606584
Pubmed	PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.	MKI67 CUX1	1.57e-04	7	96	2	26043730
Pubmed	Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.	FGF8 DNMT1	1.57e-04	7	96	2	31558711
Pubmed	S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.	MKI67 CUX1	1.57e-04	7	96	2	23359715
Pubmed	SHC and SHIP phosphorylation and interaction in response to activation of the FLT3 receptor.	SYK LCK	1.57e-04	7	96	2	10482988
Pubmed	Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors.	SYK LCK	1.57e-04	7	96	2	7721825
Pubmed	EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling.	MKI67 CUX1	1.57e-04	7	96	2	25978062
Pubmed	Evidence of LAT as a dual substrate for Lck and Syk in T lymphocytes.	SYK LCK	1.57e-04	7	96	2	16938345
Pubmed	RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.	A2M TCOF1 PHF3 PDIA3 GNL3	1.58e-04	183	96	5	28186131
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CDC42EP4 DSG2 PI4KA APBB2 MACF1 MAP4K4 PDIA3	1.71e-04	421	96	7	36976175
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	MAGED1 TAF9B MKI67 CUX1	1.81e-04	101	96	4	26949739
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	FLII ST13P4 SLMAP MKI67 HSP90AA5P PDIA3 YWHAH CUX1	1.92e-04	573	96	8	28330616
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCOF1 MKI67 BRD3 TOP1MT	1.96e-04	103	96	4	32744500
Pubmed	Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex.	MKI67 CUX1	2.09e-04	8	96	2	33594090
Pubmed	Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis.	MKI67 FGF8	2.09e-04	8	96	2	19660449
Pubmed	Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons.	MKI67 CUX1	2.09e-04	8	96	2	34188164
Pubmed	Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons.	MKI67 FGF8	2.09e-04	8	96	2	22040872
Pubmed	Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.	SYK LCK	2.09e-04	8	96	2	12359715
Pubmed	Critical role of the BAF chromatin remodeling complex during murine neural crest development.	MKI67 PLXNA2	2.09e-04	8	96	2	33750945
Pubmed	Development of the mammalian urethra is controlled by Fgfr2-IIIb.	MKI67 FGF8	2.09e-04	8	96	2	15843416
Pubmed	Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice.	FGF8 PLXNA2	2.09e-04	8	96	2	16687131
Pubmed	ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.	SLMAP MKI67	2.09e-04	8	96	2	27562601
Cytoband	3p21.1	CHDH GNL3 DNAH1	9.59e-05	42	96	3	3p21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	CCDC71 ZNF35 CHDH GNL3 DNAH1	5.49e-04	316	96	5	chr3p21
GeneFamily	Gelsolin/villins	FLII SCIN	3.30e-04	8	63	2	950
GeneFamily	AT-rich interaction domain containing	KDM5C ARID5B	1.22e-03	15	63	2	418
GeneFamily	Cadherin related	FAT4 FAT2	1.57e-03	17	63	2	24
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	SNED1 KLHL5 UPF2 FGD2 TCOF1 ARID5B SYK MAP4K4	7.75e-09	190	95	8	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FGD2 TCOF1 SYK RFC2 GNL3 DNMT1	2.68e-06	183	95	6	956ff95aef9c5521b6a3ba7ac6df0aad242c1c35
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHF3 SMARCD2 LCK MAP4K4 CUX1 DNM2	3.76e-06	194	95	6	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	severe_COVID-19-CD4+_T_naive\|severe_COVID-19 / disease group, cell group and cell class (v2)	CHMP7 FAM153A TSHZ2 ARID5B LCK GNL3	3.76e-06	194	95	6	4b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL5 TRIM2 CLCN3 MAP4K4 EVI5L DNM2	4.48e-06	200	95	6	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DSG2 TSHZ2 SYK MCF2 YWHAH	6.18e-06	121	95	5	05c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXLNB SLMAP MACF1 CMYA5 HDLBP	3.77e-05	176	95	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M FLII CHDH DNM2 HDLBP	4.20e-05	180	95	5	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAM153A SYK ARL15 SCIN IQUB	4.54e-05	183	95	5	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	COPD-Lymphoid-B\|COPD / Disease state, Lineage and Cell class	SNED1 KLHL5 UPF2 ARID5B MAP4K4	4.78e-05	185	95	5	925e79c35c381dd44ec5fb921dca09ce43140135
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	A2M FAT4 APBB2 ARL15 PLXNA2	5.03e-05	187	95	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	severe_COVID-19-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	CHMP7 FAM153A TSHZ2 ARID5B GNL3	5.56e-05	191	95	5	55a282478488efd1561ea57a6f0218f55f711bb0
ToppCell	droplet-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 SMARCD2 LCK YWHAH CUX1	5.70e-05	192	95	5	041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCell	droplet-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 SMARCD2 LCK YWHAH CUX1	5.70e-05	192	95	5	d9e61b2722aa81e4f6e11865a04f2f1e75b794ab
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	A2M SNED1 FAT4 TSHZ2 APBB2	5.84e-05	193	95	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCD2 LCK MAP4K4 CUX1 DNM2	5.99e-05	194	95	5	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SNED1 FAT4 CLCN3 TSHZ2 MACF1	5.99e-05	194	95	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCD2 LCK MAP4K4 CUX1 DNM2	5.99e-05	194	95	5	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHMP7 FAM153A TSHZ2 ARID5B LCK	6.14e-05	195	95	5	d9965223430aba1ec0b1b77b5bd40d3a01e42e95
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CHMP7 FAM153A TSHZ2 ARID5B LCK	6.14e-05	195	95	5	1d3c51a3be5ad1fbc465c5f684565ec4c6f35f54
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M SERPINA3 FAT4 MACF1 MUSK	6.44e-05	197	95	5	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M SNED1 FAT4 TSHZ2 APBB2	6.44e-05	197	95	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M SNED1 FAT4 TSHZ2 APBB2	6.44e-05	197	95	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CHMP7 FAM153A TSHZ2 ARID5B LCK	6.44e-05	197	95	5	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	cellseq2-Epithelial\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SERPINA3 TRIM2 DSG2 HDLBP CYB561	6.75e-05	199	95	5	2d4fb558845764f937efaf39962caaeb2c85478b
ToppCell	cellseq2-Epithelial-Epithelial_Glandular\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SERPINA3 TRIM2 DSG2 HDLBP CYB561	6.75e-05	199	95	5	ca78fd6e310232b25b864ed02ff9242fe1aa8206
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 MAGED1 CDC42EP4 TSHZ2 MACF1	6.75e-05	199	95	5	2cec0e370ee9bb3c88a7acb5519e9ea8ddb399bc
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TSHZ2 PHF3 ARID5B MACF1 LCK	6.75e-05	199	95	5	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAT2 DSG2 TSHZ2 CMYA5 PDIA3	6.75e-05	199	95	5	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT2 CDC42EP4 DSG2 TSHZ2 CMYA5	6.75e-05	199	95	5	c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT2 DSG2 TSHZ2 CMYA5 PDIA3	6.75e-05	199	95	5	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNED1 MAGED1 CDC42EP4 TSHZ2 MACF1	6.75e-05	199	95	5	9e87b64e16d595701c3beb07aa835afe3330bd10
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT2 DSG2 TSHZ2 CMYA5 PDIA3	6.75e-05	199	95	5	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT2 TRIM2 ARSD TSHZ2 AHNAK2	6.92e-05	200	95	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	A2M FGD2 SYK SCIN YWHAH	6.92e-05	200	95	5	a1503bcc774bed9563eda7cf90b8b5bf4405ad85
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_T_naive\|Leuk-UTI / Disease, condition lineage and cell class	CHMP7 FAM153A GAMT TSHZ2 LCK	6.92e-05	200	95	5	a542c302ac266ed0ead355b5011f0aff39320ed7
ToppCell	(5)_Epithelial_cells-(5)_Epi_dividing\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	TCOF1 MKI67 RFC2 YWHAH DNMT1	6.92e-05	200	95	5	b46b2064362efc64edf19ab2b21bc89047c9d943
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	A2M FGD2 SYK SCIN YWHAH	6.92e-05	200	95	5	25247f8b6ba6cd899ba6bd47e28e090d697e4632
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAT2 TRIM2 ARSD TSHZ2 AHNAK2	6.92e-05	200	95	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_naive\|COVID-19_Mild / Disease, condition lineage and cell class	CHMP7 FAM153A TSHZ2 ARID5B LCK	6.92e-05	200	95	5	a51b61afc3fd2e548489901a86fb9d1c5bd3f95f
Disease	total blood protein measurement	SERPINA3 TXLNB ARID5B SYK MACF1 ARL15 MUSK DNAH1 HDLBP	1.05e-05	449	91	9	EFO_0004536
Disease	Headache	ATG13 IFT81 MACF1 CUX1	4.67e-05	64	91	4	HP_0002315
Disease	level of Phosphatidylcholine (16:0_22:4) in blood serum	MAP4K4 MUSK	3.34e-04	9	91	2	OBA_2045078
Disease	adseverin measurement	CYP11B1 SCIN	4.17e-04	10	91	2	EFO_0801358
Disease	cardiovascular disease	USP38 CHDH ARID5B KYAT3 ARL15 DNMT1 CYB561	5.40e-04	457	91	7	EFO_0000319
Disease	cortical surface area measurement	CHMP7 TRIM2 USP38 ATG13 PRSS55 MACF1 MSH5 QSER1 ARL15 MAP4K4 PLXNA2 CUX1	8.67e-04	1345	91	12	EFO_0010736
Disease	stomach cancer (is_marker_for)	KDM5C MKI67 MAP4K4 CUX1	9.93e-04	142	91	4	DOID:10534 (is_marker_for)
Disease	X-24309 measurement	FBF1 MIDEAS	1.72e-03	20	91	2	EFO_0800872
Disease	lung adenocarcinoma (is_marker_for)	SERPINA3 MKI67 MAP4K4	2.33e-03	85	91	3	DOID:3910 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDMEKRNSSLPDENN	EVI5L	486	Q96CN4
NKPTDDIVLMAQALE	BRD3	116	Q15059
ANAFKPNILLIMADD	ARSD	36	P51689
QSMAEDLDSLPEKLA	ATG13	486	O75143
DKPVGMDILNSAIEN	APBB2	601	Q92870
ILQPCSLDDMDALKD	ARL15	171	Q9NXU5
DEPQMLTNEKLSIFD	DNMT1	376	P26358
AMKAVTELNEPLSNE	YWHAH	26	Q04917
NASALFILPDQDKME	SERPINA3	271	P01011
EMEAQQAALDPALKQ	CUX1	716	P39880
RMPKLSQVNESDADD	FAT4	4866	Q6V0I7
TAAENKENLDPSNLM	HCCS	71	P53701
RPSQAEEQALSMDFK	CYB561	226	P49447
DQSVLLMKPDAELSA	A2M	601	P01023
LNAPTIMIAEKAADI	CHDH	556	Q8NE62
LDPDTMQALEKSNDE	QSER1	1561	Q2KHR3
MQALEKSNDELLLPH	QSER1	1566	Q2KHR3
TLVMKINATDADEPN	DSG2	176	Q14126
LEDAQESKALVNMPG	EXO5	31	Q9H790
MANDSPAKSLVDIDL	MAP4K4	1	O95819
PDEAKLAEDILNTMF	FLII	1111	Q13045
LDIAQDPAQKDTMLG	IFT122	926	Q9HBG6
EMADIQVSAAAARPK	MAGED1	61	Q9Y5V3
PALKDELLAEANVMQ	SYK	411	P43405
MDNKISPEAQVAELE	CFAP52	1	Q8N1V2
DPTANDINAAITKEM	HSP90AA5P	301	Q58FG0
ADIAKLPAISDQDMN	PLXNA2	1816	O75051
VDIIDENDNAPMFLK	FAT2	1746	Q9NYQ8
LKEAAQLVPNDMESL	LRRC36	591	Q1X8D7
EARQMLSKEADASPA	NUP85	211	Q9BW27
AEETILNAFKMLDPD	MYL5	101	Q02045
PAKLNRQDAMLVDEL	EPX	526	P11678
MQVDPATLAKSDLED	FAM153A	201	Q9UHL3
KSLDAIVASVMEANP	PI4KA	346	P42356
SPDAFLAEANLMKQL	LCK	281	P06239
PDMEAFQQELALLKI	PAGE2B	66	Q5JRK9
PSQAEDVQAALVALM	GDPGP1	366	Q6ZNW5
AKRIEPAEELNSNDM	MKI67	3056	P46013
PAEELNSNDMKTNKE	MKI67	3061	P46013
ILAVTPANMDLANSD	DNM2	171	P50570
PANMDLANSDALKLA	DNM2	176	P50570
IAKLLASDDMNIPNE	KLHL5	366	Q96PQ7
QPMAERKAQLDALAF	MACF1	3536	Q9UPN3
LANKRINAMAEDGDP	FGF8	86	P55075
MNDPLSAIDAEQLEK	DNAH1	1041	Q9P2D7
ALEEALLVFNPMSQD	CCDC71	26	Q8IV32
ISEADPQALLQAMKD	FBF1	66	Q8TES7
QLKSMRQAAADAKPE	IFT81	246	Q8WYA0
MDPDKQDALNSIENS	DYTN	1	A2CJ06
SNMLGDNKVPAEEVL	CHMP7	136	Q8WUX9
PEDMLNAAAALDSAL	C14orf93	251	Q9H972
PTAALTLKAADEQMA	CMYA5	1186	Q8N3K9
AMSLPQLNEKEAAEK	CDC42EP4	116	Q9H3Q1
NAELSPDAIKANSME	CYP11B1	296	P15538
KALQDIENFLEMALP	MCF2	361	P10911
DMNPELRKALLQDSA	MIDEAS	316	Q6PJG2
MQRPNDDSLAFLDKI	IQUB	101	Q8NA54
MAIAASKVQEAPIDE	GAMT	71	Q14353
QAPDQADAQKALDMI	FGD2	266	Q7Z6J4
VKPMEAASAILSQAD	GNL3	331	Q9BVP2
PKLLDTVDDMLANDI	EHD1	376	Q9H4M9
DVSLLDPDLSDMKNN	KYAT3	376	Q6YP21
DLEREVAQMKQAALP	C19orf25	96	Q9UFG5
PDMEAFQQELALLKI	PAGE2	66	Q7Z2X7
PNCVNRDLIDKAAMD	UPF2	576	Q9HAU5
FMKLDLEDPNLDLNV	MSH5	806	O43196
MLVAAAAERNKDPIL	METTL26	1	Q96S19
LSFSPMAKNAENEDL	FNDC8	121	Q8TC99
NAPRDALVMAQILKD	TAF9B	11	Q9HBM6
EDASAMLKEVQPRAQ	ST13P4	211	Q8IZP2
REALAAMNAAQVKPL	TCOF1	486	Q13428
ANPQERKAAMKTAEE	SCIN	301	Q9Y6U3
DPNIVIAKMDATAND	PDIA3	426	P30101
KELQALSRQPAEMAA	PLEKHJ1	6	Q9NW61
LNFLEDNPSLKDIML	SIK2	526	Q9H0K1
ASAQLENMEEAPKRV	SNED1	1276	Q8TER0
ENMEEAPKRVSLALQ	SNED1	1281	Q8TER0
EVDDPLKAQMSNFLA	SMARCD2	411	Q92925
FNLDKVPCLASMIED	EIF4ENIF1	311	Q9NRA8
NVEAAMSLQLPEADA	AHNAK2	5241	Q8IVF2
ANQNETEDDKLPAMA	ARID5B	606	Q14865
NDMNASKIVDDIPDR	CLCN3	476	P51790
DMAVVLKATQEAPAA	ZNF35	71	P13682
QMDEQDLNEPLAKVS	SLMAP	466	Q14BN4
NLQLFMENKDPRDDL	TOP1MT	386	Q969P6
EAAMEIQEPAANKSL	PHF3	1071	Q92576
PALKDAMLELNASND	RFC2	96	P35250
MNEKTAAINADELPT	SPTA1	386	P02549
PSAVFEQDLENKEMS	USP38	896	Q8NB14
LDPLAVEKMQSLSEA	TSHZ2	421	Q9NRE2
ANMDNDIALLLLASP	PRSS55	151	Q6UWB4
APAKAQSALTEEMLE	TASOR2	626	Q5VWN6
QAPTEASLQKMEADV	TXLNB	616	Q8N3L3
NLDNVVEDSMLVDPK	HDLBP	796	Q00341
LDEDFTDQLSLMQLP	TCHHL1	676	Q5QJ38
QMSEKLNELADQDFP	TRIM2	276	Q9C040
LPVAMEAATNKDELI	USP13	501	Q92995
LVMERSEELNKDLNP	YRDC	151	Q86U90
MAACPEKLDLNLAAA	KDM5C	651	P41229
EAALMAEFDNPNIVK	MUSK	626	O15146