Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5'-3' DNA helicase activity

BRIP1 DDX12P DDX11

1.73e-0511963GO:0043139
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

BRIP1 DDX12P PPAT DDX11

7.64e-0547964GO:0051539
GeneOntologyMolecularFunctiontriplex DNA binding

DDX12P DDX11

1.36e-044962GO:0045142
GeneOntologyMolecularFunctionDNA helicase activity

BRIP1 DDX12P DDX11 HFM1

2.26e-0462964GO:0003678
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BRIP1 DDX12P MSH5 DDX11 HFM1

3.70e-04127965GO:0008094
GeneOntologyMolecularFunctioniron-sulfur cluster binding

BRIP1 DDX12P PPAT DDX11

5.45e-0478964GO:0051536
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

BRIP1 DDX12P DDX56 DDX11

6.00e-0480964GO:0008186
GeneOntologyMolecularFunctionlaminin-1 binding

PXDN NID1

6.29e-048962GO:0043237
GeneOntologyMolecularFunctionmetal cluster binding

BRIP1 DDX12P PPAT DDX11

6.89e-0483964GO:0051540
GeneOntologyMolecularFunctionhelicase activity

BRIP1 DDX12P DDX56 DDX11 HFM1

9.97e-04158965GO:0004386
DomainGPS

ADGRV1 PKDREJ PKD1 ADGRF5

2.49e-0534944SM00303
DomainGPS

ADGRV1 PKDREJ PKD1 ADGRF5

3.50e-0537944IPR000203
DomainGuanylate_kinase_CS

MAGI1 MAGI3 MAGI2

6.59e-0516943IPR020590
DomainHelicase_C_2

BRIP1 DDX11

1.49e-044942PF13307
DomainDEAD_2

BRIP1 DDX11

1.49e-044942PF06733
DomainDEAD_2

BRIP1 DDX11

1.49e-044942IPR010614
DomainATP-dep_Helicase_C

BRIP1 DDX11

1.49e-044942IPR006555
DomainHelicase-like_DEXD_c2

BRIP1 DDX11

1.49e-044942IPR006554
DomainDNA_helicase_DNA-repair_Rad3

BRIP1 DDX11

1.49e-044942IPR013020
DomainHELICASE_ATP_BIND_2

BRIP1 DDX11

1.49e-044942PS51193
DomainREJ

PKDREJ PKD1

1.49e-044942PS51111
DomainHelic_SF1/SF2_ATP-bd_DinG/Rad3

BRIP1 DDX11

1.49e-044942IPR014013
DomainREJ_dom

PKDREJ PKD1

1.49e-044942IPR014010
DomainDEXDc2

BRIP1 DDX11

1.49e-044942SM00488
DomainHELICc2

BRIP1 DDX11

1.49e-044942SM00491
DomainGUANYLATE_KINASE_2

MAGI1 MAGI3 MAGI2

2.03e-0423943PS50052
DomainGUANYLATE_KINASE_1

MAGI1 MAGI3 MAGI2

2.03e-0423943PS00856
DomainGuanylate_kin

MAGI1 MAGI3 MAGI2

2.95e-0426943PF00625
DomainGK/Ca_channel_bsu

MAGI1 MAGI3 MAGI2

2.95e-0426943IPR008145
DomainGuanylate_kin-like_dom

MAGI1 MAGI3 MAGI2

2.95e-0426943IPR008144
DomainGuKc

MAGI1 MAGI3 MAGI2

2.95e-0426943SM00072
DomainARM-type_fold

MON2 IPO7 ARMC3 UBR4 TSC2 SPAG6 DOCK5 NF1

3.11e-04339948IPR016024
DomainPKD/REJ-like

PKDREJ PKD1

3.71e-046942IPR002859
DomainREJ

PKDREJ PKD1

3.71e-046942PF02010
DomainARM-like

MON2 IPO7 ARMC3 TSC2 SPAG6 NF1 CEP70

4.28e-04270947IPR011989
DomainGPS

ADGRV1 PKD1 ADGRF5

7.19e-0435943PF01825
DomainGPS

ADGRV1 PKD1 ADGRF5

7.82e-0436943PS50221
Domain-

MON2 IPO7 ARMC3 TSC2 SPAG6 NF1

8.99e-042229461.25.10.10
DomainRap_GAP_dom

RALGAPB TSC2

1.34e-0311942IPR000331
DomainRAPGAP

RALGAPB TSC2

1.34e-0311942PS50085
DomainPKD_channel

PKDREJ PKD1

1.34e-0311942PF08016
DomainPKD1_2_channel

PKDREJ PKD1

1.34e-0311942IPR013122
DomainEGF_dom

CUBN NID1

1.60e-0312942IPR024731
DomainEGF_3

CUBN NID1

1.60e-0312942PF12947
DomainWW

MAGI1 MAGI3 MAGI2

1.71e-0347943PF00397
DomainWW

MAGI1 MAGI3 MAGI2

1.81e-0348943SM00456
DomainWW_DOMAIN_1

MAGI1 MAGI3 MAGI2

2.16e-0351943PS01159
DomainWW_DOMAIN_2

MAGI1 MAGI3 MAGI2

2.16e-0351943PS50020
DomainSEA

MUC16 ADGRF5

2.19e-0314942SM00200
DomainWW_dom

MAGI1 MAGI3 MAGI2

2.28e-0352943IPR001202
Domain-

MUC16 ADGRF5

2.52e-03159423.30.70.960
DomainIg_I-set

IGFN1 CEACAM5 NCAM2 PXDN ADGRF5

2.73e-03190945IPR013098
DomainI-set

IGFN1 CEACAM5 NCAM2 PXDN ADGRF5

2.73e-03190945PF07679
DomainEGF_CA

CUBN TENM2 NID1 PROC

3.36e-03122944SM00179
DomainP-loop_NTPase

MAGI1 BRIP1 ABCB5 MAGI3 DDX56 MSH5 DDX11 MAGI2 ATAD2B HFM1 HYDIN

3.52e-038489411IPR027417
DomainEGF-like_Ca-bd_dom

CUBN TENM2 NID1 PROC

3.56e-03124944IPR001881
DomainLH2

PKDREJ PKD1

3.64e-0318942SM00308
Domain-

PKDREJ PKD1

4.95e-03219422.60.60.20
DomainPLAT

PKDREJ PKD1

4.95e-0321942PF01477
DomainPLAT/LH2_dom

PKDREJ PKD1

4.95e-0321942IPR001024
DomainPLAT

PKDREJ PKD1

4.95e-0321942PS50095
Pubmed

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.

MAGI1 MAGI3 MAGI2

4.18e-07697315509766
Pubmed

Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.

MAGI1 MAGI3 MAGI2

1.17e-06897316316992
Pubmed

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.

MAGI1 LNX2 MAGI3 MAGI2

3.13e-063697426053890
Pubmed

Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.

MAGI1 MAGI3 MAGI2

5.89e-061397323576434
Pubmed

The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.

TSC2 PKD1

7.70e-0629728661056
Pubmed

MAGI-1: a widely expressed, alternatively spliced tight junction protein.

MAGI1 MAGI3

7.70e-06297211969287
Pubmed

Precystectomy serum levels of carbohydrate antigen 19-9, carbohydrate antigen 125, and carcinoembryonic antigen: prognostic value in invasive urothelial carcinoma of the bladder.

CEACAM5 MUC16

7.70e-06297224680660
Pubmed

hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.

BRIP1 MSH5

7.70e-06297226055704
Pubmed

Renal Neoplasia in Polycystic Kidney Disease: An Assessment of Tuberous Sclerosis Complex-associated Renal Neoplasia and PKD1/TSC2 Contiguous Gene Deletion Syndrome.

TSC2 PKD1

7.70e-06297234876325
Pubmed

Two novel gross deletions of TSC2 in Malaysian patients with tuberous sclerosis complex and TSC2/PKD1 contiguous deletion syndrome.

TSC2 PKD1

7.70e-06297224683199
Pubmed

Imaging features of tuberous sclerosis complex with autosomal-dominant polycystic kidney disease: a contiguous gene syndrome.

TSC2 PKD1

7.70e-06297225355409
Pubmed

Trajectories of Perioperative Serum Tumor Markers and Colorectal Cancer Outcomes: A Retrospective, Multicenter Longitudinal Cohort Study.

CEACAM5 MUC16

7.70e-06297234801967
Pubmed

Acrofacial dysostosis in a patient with the TSC2-PKD1 contiguous gene syndrome.

TSC2 PKD1

7.70e-06297211836366
Pubmed

Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.

MAGI1 MAGI2

7.70e-06297223523645
Pubmed

Analysis of PKD1 for genomic deletion by multiplex ligation-dependent probe assay: absence of hot spots.

TSC2 PKD1

7.70e-06297218060739
Pubmed

TSC2/PKD1 contiguous gene syndrome, with emphasis on a case with an atypical mild polycystic kidney phenotype and a novel genetic variant.

TSC2 PKD1

7.70e-06297231176519
Pubmed

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.

DDX12P DDX11

7.70e-06297232855419
Pubmed

MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis.

MAGI1 MAGI3

7.70e-06297233712709
Pubmed

MAGI1 copy number variation in bipolar affective disorder and schizophrenia.

MAGI1 MAGI2

7.70e-06297222381734
Pubmed

Localization of chi1-related helicase genes to human chromosome regions 12p11 and 12p13: similarity between parts of these genes and conserved human telomeric-associated DNA.

DDX12P DDX11

7.70e-0629728833153
Pubmed

Significance of serum tumor marker levels in peritoneal carcinomatosis of appendiceal origin.

CEACAM5 MUC16

7.70e-06297222941175
Pubmed

Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.

DDX12P DDX11

7.70e-0629729013641
Pubmed

Diagnosis and genotype-phenotype correlation in patients with PKD1/TSC2 contiguous gene deletion syndrome.

TSC2 PKD1

7.70e-06297235142283
Pubmed

Polycystin 1 is required for the structural integrity of blood vessels.

TSC2 PKD1

7.70e-06297210677526
Pubmed

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.

MAGI1 MAGI3 MAGI2

9.34e-061597323782696
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MAGI1 PTBP2 RALGAPB AGPAT3 MAGI3 NCAM2 DDX56 ZNF385B MSH5 ADGRV1 DOCK5 PXDN DPP9 SLC9A7 IFT122

1.58e-051489971528611215
Pubmed

Clinical Evaluation of Tumor Markers for Diagnosis in Patients with Non-small Cell Lung Cancer in China.

CEACAM5 MUC16

2.31e-05397226163610
Pubmed

Serum concentrations of CA 125, CA 15-3, CA 19-9 and CEA in normal pregnancy: a longitudinal study.

CEACAM5 MUC16

2.31e-05397221792548
Pubmed

MAGI2-AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2.

MAGI2 TET1

2.31e-05397232730644
Pubmed

Preoperative serum carbohydrate antigen 125 level is an independent negative prognostic marker for overall survival in colorectal cancer.

CEACAM5 MUC16

2.31e-05397220373053
Pubmed

A novel model for extrapleural cavity metastasis assessment in patients with lung cancer.

CEACAM5 MUC16

2.31e-05397233709781
Pubmed

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

DDX12P DDX11

2.31e-05397217611414
Pubmed

Effect of freeze-thaw cycles on serum measurements of AFP, CEA, CA125 and CA19-9.

CEACAM5 MUC16

2.31e-05397217852813
Pubmed

Detecting Low-Variant Allele Frequency Mosaic Pathogenic Variants of NF1, TSC2, and AKT3 Genes from Blood in Patients with Neurodevelopmental Disorders.

TSC2 NF1

2.31e-05397237088138
Pubmed

Concurrent Reduced Expression of Contiguous PKD1, TSC2 and NTHL1 Leading to Kidney Diseases and Multiple Diverse Renal Cancers.

TSC2 PKD1

2.31e-05397236581342
Pubmed

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.

TSC2 PKD1

2.31e-05397219321600
Pubmed

Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer.

CEACAM5 MUC16

2.31e-05397234621407
Pubmed

Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.

MAGI3 MAGI2

2.31e-05397215652357
Pubmed

Microtubule-bundling protein Spef1 enables mammalian ciliary central apparatus formation.

SPAG6 HYDIN

2.31e-05397230535028
Pubmed

Mammalian ChlR1 has a role in heterochromatin organization.

DDX12P DDX11

2.31e-05397221854770
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

GPD1 CEACAM5 ARMC3 ADGRV1 ENPP4 CUBN GDF2 LDHB RYR1 EML5 PKD1 NID1

2.64e-051016971219056867
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

MAGI1 SLC25A33 MAGI3 ADGRV1 MAGI2 MTX2 NF1 TFB1M

2.83e-0543097832581705
Pubmed

Clinical value of p53, c-erbB-2, CEA and CA125 regarding relapse, metastasis and death in resectable non-small cell lung cancer.

CEACAM5 MUC16

4.60e-05497214566828
Pubmed

Clinical evaluation and therapeutic monitoring value of serum tumor markers in lung cancer.

CEACAM5 MUC16

4.60e-05497226560853
Pubmed

Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.

TSC2 PKD1

4.60e-05497220169078
Pubmed

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

TSC2 PKD1

4.60e-05497219255143
Pubmed

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.

TSC2 PKD1

4.60e-05497218845692
Pubmed

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.

DOCK5 PLD2

4.60e-05497223362269
Pubmed

Clinical Performance of CEA, CA19-9, CA15-3, CA125 and AFP in Gastrointestinal Cancer Using LOCI™-based Assays.

CEACAM5 MUC16

4.60e-05497228011514
Pubmed

Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.

MAGI1 MAGI3 MAGI2

4.63e-052597323873930
Pubmed

Polycystin channels and kidney disease.

PKDREJ PKD1

7.66e-05597211698076
Pubmed

The efficacy of serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) levels in determining the malignancy of solitary pulmonary nodules.

CEACAM5 MUC16

7.66e-05597219383238
Pubmed

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.

RYR1 PKD1

7.66e-05597211818962
Pubmed

Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study.

CEACAM5 MUC16

7.66e-05597218609108
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

MSH5 TET1 HFM1

9.84e-053297327739607
Pubmed

Analysis of mouse embryonic patterning and morphogenesis by forward genetics.

DDX12P DDX11 IFT122

1.08e-043397315755804
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM6 PKDREJ PKD1

1.08e-043397319834762
Pubmed

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

MAGI1 MAGI2

1.15e-0469729647693
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

MAGI1 MAGI3 MAGI2

1.18e-043497330726710
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

MAGI1 LNX2 MAGI2

1.29e-043597333864728
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 RALGAPB TENM2 EPG5 MAGI2 PXDN PLXNA2

1.48e-0440797712693553
Pubmed

Tissue expression patterns identify mouse cilia genes.

ARMC3 SPAG6 FAM217A HYDIN

1.55e-049697417971504
Pubmed

Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3.

TSC2 PKD1

1.60e-0479728828041
Pubmed

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.

MAGI3 MAGI2

1.60e-04797224025447
Pubmed

Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner.

TSC2 NF1

1.60e-04797221896734
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

MUC16 BTBD1 TENM2 SLC25A51 RYR1 DOCK5 ESYT3 CATSPERB

1.61e-0455297810737800
Pubmed

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

UBR4 ZFYVE26

2.13e-04897237871017
Pubmed

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.

DDX12P DDX11

2.13e-04897222678773
Pubmed

Analysis of the sperm flagellar axoneme using gene-modified mice.

SPAG6 CFAP54

2.13e-04897232554934
Pubmed

Cloning and expression analysis of murine phospholipase D1.

NF1 PLD2

2.13e-0489729307024
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPM6 PKDREJ PKD1

2.56e-044497319322198
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKDREJ PKD1

3.41e-041097216805797
Pubmed

Molecular neurobiology of mTOR.

TSC2 NF1

3.41e-041097227889578
Pubmed

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.

MAGI1 MAGI3

3.41e-041097219071123
Pubmed

Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease.

C7orf25 NID1

3.41e-041097212446740
Pubmed

DSCAM regulates delamination of neurons in the developing midbrain.

MAGI1 MAGI2

4.17e-041197232917586
Pubmed

WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.

TLR6 NF1 DPP9

4.21e-045297330655611
Pubmed

Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

RYR1 PXDN GPX6

4.45e-045397336265442
Pubmed

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

DDX56 PWP1 TFB1M MRPL9

5.53e-0413497428695742
Pubmed

Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.

PPAT LDHB

5.89e-041397231545012
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

LNX2 TSC2 PKDREJ

6.41e-046097322889411
Pubmed

Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice.

ARMC3 TENM2

6.85e-041497226449520
Pubmed

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.

BRIP1 PPAT

7.89e-041597222678361
Pubmed

EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.

TENM2 TET1

7.89e-041597226576615
Pubmed

The LIFEdb database in 2006.

MON2 NT5C3A BTBD1 SPAG6 SEC61G NCOA7 ADGRF5 PLD2

9.30e-0472097816381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

MON2 NT5C3A BTBD1 SPAG6 SEC61G NCOA7 ADGRF5 PLD2

9.47e-0472297815489336
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

PTBP2 NT5C3A DDX56 LDHB RYR1 PWP1 MTX2 MRPL9

1.03e-0373297834732716
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CEACAM5 NCAM2 PXDN ADGRF5

1.12e-0316297425826454
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

MAGI1 TP53BP2

1.14e-03189729169421
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

MON2 NT5C3A DDX56 ADGRV1 BTBD1 SPAG6 NCOA7 ADGRF5

1.21e-0375097811230166
Pubmed

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

TSC2 SPAG6 MDP1 NF1 DPP9

1.41e-0329397531741433
Pubmed

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

BRIP1 LDHB TP53BP2

1.43e-037997325502805
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

WDR81 TSC2 HYDIN

1.48e-038097319389623
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

NCAM2 TSC2 GDF2 MAGI2 PLD2

1.56e-0330097519086053
Pubmed

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.

NID1 IFT122

1.56e-032197221703454
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

CUBN PKD1

1.56e-032197227591083
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MAGI1 LNX2 RALGAPB TSC2 NF1 TP53BP2

1.59e-0344697624255178
Pubmed

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.

RYR1 TFB1M

1.71e-032297235081489
Pubmed

Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.

TSC2 PKD1

1.71e-032297227582005
Pubmed

DNA cloning using in vitro site-specific recombination.

MON2 NT5C3A BTBD1 SPAG6 SEC61G NCOA7 ADGRF5 PLD2

1.73e-0379497811076863
Cytoband10p12.31

ARMC3 CUBN

9.93e-042297210p12.31
Cytoband3q22.3

ESYT3 CEP70

1.28e-03259723q22.3
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MAGI1 MAGI3 MAGI2

1.19e-0426673904
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGFN1 CEACAM5 NCAM2 PXDN ADGRF5

3.26e-04161675593
GeneFamilyDEAD-box helicases

DDX12P DDX56 DDX11

5.04e-0442673499
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

WDR81 TSC2 RYR1 HYDIN TP53BP2

5.56e-04181675694
GeneFamilyDNA helicases

BRIP1 DDX11

1.77e-03176721167
GeneFamilyPDZ domain containing

MAGI1 LNX2 MAGI3 MAGI2

2.44e-031526741220
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5 PLXNA2

3.50e-10191969ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 DOCK5 ESYT3 CEP70 ADGRF5

5.03e-101999698587bd98de7767a575088afbea07a1feb4516b9b
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5 B4GALNT3

7.75e-09188968c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 DOCK5 CEP70 ADGRF5

7.75e-09188968707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5 B4GALNT3

9.14e-09192968499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5 B4GALNT3

9.14e-09192968efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 NCOA7 ADGRF5

9.91e-0919496853f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 NCOA7 ADGRF5

1.03e-081959689406866f99555198a9be311fbd65751b70f35446
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

1.21e-08199968725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 DOCK5 CEP70 ADGRF5

1.21e-081999685cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 NCOA7 ADGRF5

1.34e-07181967c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

MAGI1 LNX2 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

1.44e-071839678e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

1.61e-071869672ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

1.67e-0718796781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

MAGI1 LNX2 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

1.73e-07188967eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5 PLXNA2

1.93e-07191967d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 ADGRF5 B4GALNT3

1.93e-07191967e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 ZNF385B ADGRV1 B4GALNT3 HYDIN

2.00e-071929670644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

2.00e-0719296729f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

2.00e-07192967fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN PROC

2.22e-07195967e525b69145059b66417589601f7109af63730f3a
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

2.55e-071999675f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 CEP70 CATSPERB ADGRF5 B4GALNT3 PLXNA2

8.31e-071489669fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ZNF385B ADGRV1 CEP70

1.62e-06166966c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellControl|World / group, cell type (main and fine annotations)

MAGI1 CEACAM5 MAGI3 ZNF385B ADGRV1 ADGRF5

1.74e-06168966a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

1.80e-0616996614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1 ADGRF5

2.51e-06179966a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 CEP70 CATSPERB ADGRF5 B4GALNT3 PLXNA2

2.68e-06181966576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

MAGI1 MAGI3 ZNF385B ADGRV1 ADGRF5 PLXNA2

2.85e-06183966dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

2.85e-061839666847c1252d6bb105524f812658112517fd351eab
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ZNF385B ADGRV1 CEP70

3.04e-06185966673f0c688ae6984bc8027df2da335787924f4137
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

MAGI1 MAGI3 ADGRV1 CEP70 ADGRF5 B4GALNT3

3.04e-06185966cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.04e-06185966f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.04e-0618596618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

MAGI1 LNX2 MAGI3 ADGRV1 ADGRF5 B4GALNT3

3.13e-061869663006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

3.23e-061879665df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CUBN PCDH12 PXDN NID1 ADGRF5 PLXNA2

3.54e-0619096606bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

3.54e-0619096627a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 ESYT3 ADGRF5

3.65e-0619196634cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

3.65e-06191966a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

3.65e-06191966276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.65e-06191966e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.65e-061919669d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.65e-061919661c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

MAGI1 PDE1A SYNM CASP12 NID1 CATSPERB

3.76e-06192966f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

3.76e-0619296658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.76e-06192966eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

MAGI1 PDE1A CASP12 PXDN NID1 CATSPERB

3.88e-0619396625bdc557055b5bce6a21f8696b48e991c696b979
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI3 ZNF385B ADGRV1 CEP70 NCOA7 ADGRF5

3.88e-06193966fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAGI3 ZNF385B ADGRV1 CEP70 NCOA7 ADGRF5

3.88e-06193966f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

3.88e-06193966a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.99e-06194966756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

3.99e-0619496643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 CFAP54 ADGRF5 HYDIN

4.11e-06195966fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 SPAG6 CFAP54 HYDIN

4.11e-0619596621dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 CFAP54 ADGRF5 HYDIN

4.11e-06195966eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

4.11e-061959669651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

4.24e-06196966de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 CFAP54 ADGRF5 HYDIN

4.24e-06196966af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

MAGI1 ARMC3 SAXO2 CFAP54 ADGRF5 HYDIN

4.24e-061969666d02d494196e3f857d53eea46d9419690d43beca
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKK1 ARMC3 MUC16 SAXO2 SPAG6 HYDIN

4.36e-0619796615b4d1203943ce90a7083178d4a4284d9b323071
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 MAGI3 ZNF385B ADGRV1 MAGI2 NF1

4.49e-061989661996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

ARMC3 SAXO2 CFAP54 EML5 IFT122 HYDIN

4.49e-061989666d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEACAM5 ARMC3 MUC16 SAXO2 SPAG6 HYDIN

4.49e-06198966d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

4.62e-061999662498237b9e895ca4826a3378d9d40989968df72b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARMC3 MUC16 SAXO2 SPAG6 CFAP54 HYDIN

4.62e-06199966542ec45c931b40738df1f3777b00c83be33a514a
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MON2 MAGI1 PTBP2 MAGI3 MAGI2 NF1

4.62e-0619996694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

4.76e-06200966acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

4.76e-06200966ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAGI3 ZNF385B ADGRV1 ESYT3 CEP70 ADGRF5

4.76e-06200966eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE1A ZNF385B CUBN ESYT3 EML5

1.23e-05138965611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellICU-SEP-Lymphocyte-T_NK-CD8_Naive|ICU-SEP / Disease, Lineage and Cell Type

NT5C3A DENND2D LDHB PXDN CEP70

1.79e-05149965a66f3ebf6214b269b137ddd5f4d8d7fb3ef2d962
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 SAXO2 SPAG6 CFAP54 HYDIN

1.90e-051519659d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

ARMC3 MUC16 SPAG6 CFAP54 HYDIN

1.90e-051519658216462e723fec2797387929dde095370947e10a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKK1 IGFN1 TENM2 DOCK5 MAGI2

2.16e-0515596590e629681a72baacc7981b82883866a487638dbc
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ADGRV1 CEP70

2.67e-051629655c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

MAGI1 MAGI3 ZNF385B ADGRV1 CEP70

2.75e-05163965e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 MUC16 SAXO2 SPAG6 HYDIN

2.83e-051649650e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM6 ABCB5 PCDH12 FAM217A

3.14e-05839643aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM6 ABCB5 PCDH12 FAM217A

3.14e-058396470804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM6 ABCB5 PCDH12 FAM217A

3.14e-0583964c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM6 ABCB5 PCDH12 FAM217A

3.14e-05839641e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MAGI1 MAGI3 ADGRV1 NCOA7 ADGRF5

3.36e-05170965e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 MUC16 SPAG6 CFAP54 HYDIN

3.55e-05172965187ae91148d293537afc77e10da2b64302322224
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCAM2 DOCK5 SEC61G CATSPERB PLXNA2

3.86e-051759659a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCAM2 DOCK5 SEC61G CATSPERB PLXNA2

3.86e-0517596554c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCAM2 DOCK5 SEC61G CATSPERB PLXNA2

3.86e-051759652b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

PDE1A MAGI3 ZNF385B ADGRV1 CEP70

3.97e-051769653fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 ADGRV1 CEP70 CATSPERB B4GALNT3

3.97e-051769653bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 SAXO2 SPAG6 CFAP54 HYDIN

4.07e-05177965c38138fb5ad9766c2d240811210c854338cd612e
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGAPB ITGA10 DENND2D NXPE3 ADGRF5

4.30e-05179965025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 LNX2 MAGI3 ZNF385B ADGRV1

4.30e-05179965cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ZNF385B ADGRV1

4.30e-05179965815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

PDE1A ARMC3 MAGI2 CFAP54 PXDN

4.30e-05179965e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA10 WDR81 MAGI2 PXDN NID1

4.30e-05179965a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LNX2 FAM217A DDX11 EML5 ADGRF5

4.30e-0517996508cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 PDE1A MAGI3 ADGRV1 MAGI2

4.41e-05180965b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 SAXO2 SPAG6 CFAP54 HYDIN

4.41e-05180965bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

MAGI3 ZNF385B ADGRV1 CEP70 ADGRF5

4.41e-05180965198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 MUC16 SAXO2 SPAG6 HYDIN

4.41e-05180965d9be152773fe9f2160edad9246fa03c03afeafd6
DiseaseCongenital Hydrocephalus

WDR81 IFT122 HYDIN

1.79e-068953C0020256
DiseaseMalignant neoplasm of breast

BRIP1 UBR4 CUBN PKDREJ SPAG6 LDHB SLC25A51 IFNA2 EPG5 NF1 ZFYVE26 PLD2 MRPL9 TP53BP2

8.64e-0610749514C0006142
DiseasePolycystic kidneys, severe infantile with tuberous sclerosis

TSC2 PKD1

1.03e-052952C1838327
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX12P DDX11

3.07e-053952DOID:0060535 (implicated_via_orthology)
Diseasemucocutaneous lymph node syndrome

BTBD1 CUBN EPG5 PLXNA2

1.08e-0476954EFO_0004246
Diseasemental or behavioural disorder, substance abuse

PWP1 HFM1

1.53e-046952EFO_0000677, MONDO_0002491
DiseaseCerebral ventriculomegaly

IFT122 HYDIN

2.13e-047952C1531647
DiseaseHydrocephalus Ex-Vacuo

IFT122 HYDIN

2.13e-047952C0270720
DiseaseCommunicating Hydrocephalus

IFT122 HYDIN

2.13e-047952C0009451
DiseaseFetal Cerebral Ventriculomegaly

IFT122 HYDIN

2.13e-047952C2936718
DiseasePost-Traumatic Hydrocephalus

IFT122 HYDIN

2.13e-047952C0477432
DiseaseObstructive Hydrocephalus

IFT122 HYDIN

2.13e-047952C0549423
DiseaseAqueductal Stenosis

IFT122 HYDIN

2.84e-048952C2936786
DiseaseHydrocephalus

IFT122 HYDIN

3.64e-049952C0020255
Diseasecancer antigen 125 measurement

NEU4 MUC16

4.54e-0410952EFO_0010603
Diseasepursuit maintenance gain measurement

IPO7 EPG5 MAGI2 PLXNA2

6.83e-04123954EFO_0008433
Diseasevision disorder

MAGI2 PXDN

1.20e-0316952MONDO_0021084
Diseasemelanoma

ABCB5 UBR4 CUBN IFNA2 NF1

1.26e-03248955C0025202
DiseaseMAJOR AFFECTIVE DISORDER 2

MAGI1 MAGI2

1.35e-0317952C1839839
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

TSC2 LDHB IFNA2 RYR1

1.36e-03148954C0279702
Diseasethyroid peroxidase antibody measurement

TRPM6 MAGI3 DPP9

1.64e-0372953EFO_0005666
Diseaseurinary microalbumin measurement

MON2 CUBN

1.88e-0320952EFO_0010967
Diseaselung cancer

BRIP1 TENM2

2.07e-0321952MONDO_0008903
DiseaseLeukemia, Myelocytic, Acute

BRIP1 TSC2 NF1 PXDN

2.40e-03173954C0023467
DiseaseSepticemia

IFNA2 PROC

2.70e-0324952C0036690
DiseaseSepsis

IFNA2 PROC

2.70e-0324952C0243026
DiseaseSevere Sepsis

IFNA2 PROC

2.70e-0324952C1719672
DiseaseWest Syndrome

TSC2 MAGI2

2.70e-0324952C0037769
DiseasePyemia

IFNA2 PROC

2.70e-0324952C0034189
Diseaseplatelet component distribution width

LNX2 ARMC3 ENPP4 CUBN DOCK5 ATAD2B CATSPERB ADGRF5

3.05e-03755958EFO_0007984
Diseasecortical thickness

MON2 ANKRD13B MAGI1 PTBP2 ZNF385B ADGRV1 BTBD1 TENM2 PKD1 PLXNA2

3.11e-0311139510EFO_0004840
Diseasemethionine measurement

ADGRV1 NID1

3.17e-0326952EFO_0009771
Diseaseresponse to norepinephrine-dopamine reuptake inhibitor

ADGRV1 AGMO

3.17e-0326952EFO_0007870

Protein segments in the cluster

PeptideGeneStartEntry
KLQQHSIPVFIFSAG

NT5C3A

191

Q9H0P0
GAVTVFFLQKPHLQI

ESYT3

236

A0FGR9
KFQFTPTHVGLQRLT

EPB42

651

P16452
PFIQIKVLHNPSGVF

EPG5

496

Q9HCE0
VTIGQPHLLNKFNFV

CFAP54

2191

Q96N23
LIFIAFMFQLQGIHP

CATSPERB

1071

Q9H7T0
LFQVTGDPHFNIVIT

B4GALNT3

811

Q6L9W6
LTHPINTFEPIKVQF

AGMO

261

Q6ZNB7
LNGTVHPVFSIIFAK

ABCB5

701

Q2M3G0
NKVTPLHFLVAQGSV

ANKK1

361

Q8NFD2
GIPQQHTQVLFIAKI

CEACAM5

631

P06731
DFLLVGIFPTTVHLQ

ADGRV1

1301

Q8WXG9
LKFQLKSNVIPIGHV

ARMC3

776

Q5W041
IFQKVQHSFETPNIL

CASP12

306

Q6UXS9
HTEIVKFLVQFGVNV

TP53BP2

971

Q13625
FPFQKHILLFNISIP

GDF2

126

Q9UK05
LFILNPHTGQLFVNV

PCDH12

646

Q9NPG4
KVVSVFNTLIFPLHN

OR4M2B

271

A0A0X1KG70
IPIFHILNARITFGN

ANKRD13B

421

Q86YJ7
GLPIKQVFHELSQQT

MUC16

14006

Q8WXI7
STFPVHRQKLQGFVV

IFT122

581

Q9HBG6
THAQVVKIFQSIPIG

MAGI1

531

Q96QZ7
HADVVKLFQSVPIGQ

MAGI2

486

Q86UL8
THLQVVEVLKQFPVG

MAGI3

631

Q5TCQ9
ITHFERLQQKTGIPF

MDP1

101

Q86V88
SFNNILAVLQKVFPH

ATAD2B

686

Q9ULI0
ENHTNQPFFIKTIVL

LNX2

621

Q8N448
LTFVLPTEQFHLGKI

DDX56

386

Q9NY93
VIKNPQFVFDIHKGS

PLXNA2

1751

O75051
NLKPHIQGIIQDVIF

IPO7

341

O95373
PKFRSIVHAVQAGIF

PDE1A

116

P54750
EVTFVGHPGNLVIKQ

NID1

521

P14543
FPHLQNFIKEGVLVE

ENPP4

46

Q9Y6X5
IFATAHSPIGIIIQN

HERVK_113

341

P63132
VHPQLDVVFKAVQGL

LRRC74A

386

Q0VAA2
LIQIFPALYQHIKTG

MON2

1276

Q7Z3U7
KFLLLNPAVHFAQVV

DDX11

596

Q96FC9
FFIAVLGHTPEAVQI

NEU4

101

Q8WWR8
TLQFAVHIPTFVLGL

GPR55

21

Q9Y2T6
TFPILQGHFSAVLQK

BRIP1

486

Q9BX63
TKLPQQAGNAVIVHF

HFM1

1351

A2PYH4
RTFVLNFIKIPVVPH

PROC

356

P04070
LQGFATPVFQHLQVV

RESP18

91

Q5W5W9
APVNKVIHLTFNTFA

CUBN

3191

O60494
KAEIVFQFTPFHLGI

HYDIN

4041

Q4G0P3
ISLIGDIKFQHFNPV

DOCK5

701

Q9H7D0
LQAIVSHFQKLFDVP

CEP70

466

Q8NHQ1
PGLQFFIVIVSDHQK

LINC01599

146

Q8WXQ3
AAVVIFGPLLQFHVN

FITM1

61

A5D6W6
GLIVNKAPHDFQFVQ

DPP9

46

Q86TI2
QGVKFSVFIHQPRAL

C7orf25

386

Q9BPX7
VNLFLHFTVNPKPRV

BTBD1

301

Q9H0C5
FLLLNPAVHFAQVVK

DDX12P

616

Q92771
ADILIFVVPHQFIGK

GPD1

86

P21695
FGNQFQKAETIPVLH

IFNA2

66

P01563
HPVFQTGAKVTFLLE

ITGA10

881

O75578
LQHGSLFLQTPKIVA

LDHB

66

P07195
VIVKIPFQSHLPIQA

IGFN1

566

Q86VF2
TVNQHPKFINIVATG

EML5

1421

Q05BV3
GFNVINHPIRVFTLN

FAM217A

111

Q8IXS0
VLFFLVGFAQQTLKP

GPX6

11

P59796
KLFPAVFVLPTHQNV

RYR1

1546

P21817
INEHVSGPFVQFFVK

DENND2D

371

Q9H6A0
SKVVAPGQLVHFQIL

PKD1

1896

P98161
QFILVGFSVFPHLQL

OR10H1

11

Q9Y4A9
KVPFIHVGNQVVSEL

MTX2

71

O75431
PHIFVATNFLSLVQL

MSH5

701

O43196
PNILKHVVGQFSKVL

SPAG6

426

O75602
PVTLDVLHQIFSKFG

PTBP2

191

Q9UKA9
RQFHAEKEIIFQGPI

SYNM

1226

O15061
LNKLFTHTIVPGQVL

NCOA7

141

Q8NI08
FFKVGSQLEVLVHVQ

NXPE3

116

Q969Y0
GFLFFPINVVKTRIQ

SLC25A51

226

Q9H1U9
HQNPVTLFTVLFIIL

PKDREJ

1181

Q9NTG1
VRHIFTIPGQAFVPK

TFB1M

206

Q8WVM0
IHISQPQFLKFNISL

TENM2

471

Q9NT68
GIFVPNSNIVHIFSA

SLC25A33

121

Q9BSK2
KQVHISFLPANTQGF

TET1

501

Q8NFU7
PGTNLVFHIIFAILN

ADGRF5

1241

Q8IZF2
PEIVARHFFKNLGVV

MRPL9

186

Q9BYD2
KVQTLQFHPFEAQTL

PWP1

301

Q13610
PKLVISVHGGIQNFT

TRPM6

136

Q9BX84
FLKTQFVLHLLVGFV

AGPAT3

6

Q9NRZ7
EKQAFLQVFVQPHII

NCAM2

291

O15394
GFFVKLIHIPINNII

SEC61G

51

P60059
QPFVVETLHGKIAVA

PPAT

106

Q06203
VHATAFIIVQALPQF

PXDN

421

Q92626
ASVVFPKVFPVVHNL

NF1

2646

P21359
VQKAVINHTFGVSIP

ZNF385B

136

Q569K4
VIFIHPLNTGLFRIK

RALGAPB

1391

Q86X10
NSQGHKFFRKIIPAV

SAXO2

381

Q658L1
LVFHPTSLFAIQVNI

TLR6

201

Q9Y2C9
QKHVFSPIFIIGAFV

SLC9A7

436

Q96T83
VLHPQLATGNFIIKA

UBR4

1991

Q5T4S7
LTQVQGHLVHFPLKF

PLD2

896

O14939
HVEVKVGNPFVLLQQ

ZFYVE26

1176

Q68DK2
HRKSVFFVGQLEAPQ

WDR81

1696

Q562E7
TIKGQFNFVHVIVTP

TSC2

1661

P49815