Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	establishment of cell polarity involved in ameboidal cell migration	AMOT AMOTL1 AMOTL2	2.99e-08	3	65	3	GO:0003365
GeneOntologyBiologicalProcess	establishment of cell polarity	FAT1 AMOT AMOTL1 AMOTL2 CYRIB HTT	1.99e-05	177	65	6	GO:0030010
GeneOntologyBiologicalProcess	hippo signaling	NF2 AMOT AMOTL1 AMOTL2	2.71e-05	55	65	4	GO:0035329
GeneOntologyBiologicalProcess	intracellular transport	IPO5 STAM2 RANBP2 RBSN STX4 LMAN2L NUP107 NF2 WDR11 NAPG RASSF9 YTHDC1 ALKBH5 LDLR HTT	4.92e-05	1496	65	15	GO:0046907
GeneOntologyBiologicalProcess	mRNA transport	RANBP2 NUP107 YTHDC1 ALKBH5 HTT	9.43e-05	145	65	5	GO:0051028
GeneOntologyBiologicalProcess	establishment or maintenance of cell polarity	FAT1 AMOT AMOTL1 AMOTL2 CYRIB HTT	1.58e-04	257	65	6	GO:0007163
GeneOntologyCellularComponent	lamellipodium	FAT1 STX4 NF2 AMOT AMOTL1 PALLD	7.99e-05	230	65	6	GO:0030027
GeneOntologyCellularComponent	endosome	STAM2 ATP6V1E1 RBSN STX4 NF2 GOLIM4 AMOTL2 RASSF9 KIR3DL2 MYCBPAP LDLR HTT	2.23e-04	1167	65	12	GO:0005768
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	SCARF1 STAM2 ATP6V1E1 RBSN STX4 GOLIM4 C4BPA RASSF9 KIR3DL2 MYCBPAP LDLR HTT	6.23e-04	1307	65	12	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	SCARF1 STAM2 ATP6V1E1 RBSN STX4 GOLIM4 C4BPA RASSF9 KIR3DL2 MYCBPAP LDLR HTT	7.03e-04	1325	65	12	GO:0012506
GeneOntologyCellularComponent	bicellular tight junction	AMOT AMOTL1 AMOTL2 JAM2	7.42e-04	131	65	4	GO:0005923
GeneOntologyCellularComponent	clathrin-coated vesicle	ATP6V1E1 RASSF9 MYCBPAP LDLR HTT	8.53e-04	237	65	5	GO:0030136
GeneOntologyCellularComponent	coated vesicle	ATP6V1E1 LMAN2L RASSF9 MYCBPAP LDLR HTT	8.79e-04	360	65	6	GO:0030135
GeneOntologyCellularComponent	cell leading edge	FAT1 STX4 NF2 AMOT AMOTL1 PLA2G4F PALLD	9.02e-04	500	65	7	GO:0031252
GeneOntologyCellularComponent	tight junction	AMOT AMOTL1 AMOTL2 JAM2	9.26e-04	139	65	4	GO:0070160
GeneOntologyCellularComponent	clathrin-coated vesicle membrane	ATP6V1E1 RASSF9 MYCBPAP LDLR	1.14e-03	147	65	4	GO:0030665
GeneOntologyCellularComponent	endocytic vesicle	SCARF1 STAM2 STX4 AMOT GOLIM4 LDLR	1.22e-03	384	65	6	GO:0030139
GeneOntologyCellularComponent	apical junction complex	AMOT AMOTL1 AMOTL2 JAM2	1.49e-03	158	65	4	GO:0043296
Domain	Angiomotin_C	AMOT AMOTL1 AMOTL2	3.66e-08	3	63	3	IPR024646
Domain	Angiomotin	AMOT AMOTL1 AMOTL2	3.66e-08	3	63	3	IPR009114
Domain	Angiomotin_C	AMOT AMOTL1 AMOTL2	3.66e-08	3	63	3	PF12240
Domain	EGF_3	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	1.39e-04	235	63	6	PS50026
Domain	EGF	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	1.39e-04	235	63	6	SM00181
Domain	EGF-like_dom	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	1.90e-04	249	63	6	IPR000742
Domain	EGF_1	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	2.16e-04	255	63	6	PS00022
Domain	EGF-like_CS	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	2.45e-04	261	63	6	IPR013032
Domain	EGF_2	SCARF1 FAT1 ZAN FAT3 LDLR ADAM28	2.66e-04	265	63	6	PS01186
Domain	AcylCoA_DH/ox_N	ACAD11 ACOX2	8.53e-04	13	63	2	IPR013786
Domain	-	ACAD11 ACOX2	8.53e-04	13	63	2	1.10.540.10
Domain	ConA-like_dom	FAT1 LMAN2L ZAN FAT3 CMYA5	8.57e-04	219	63	5	IPR013320
Domain	Acyl-CoA_Oxase/DH_cen-dom	ACAD11 ACOX2	1.14e-03	15	63	2	IPR006091
Domain	Acyl-CoA_dh_M	ACAD11 ACOX2	1.14e-03	15	63	2	PF02770
Domain	AcylCoA_DH/oxidase_NM_dom	ACAD11 ACOX2	1.14e-03	15	63	2	IPR009100
Domain	AcylCo_DH/oxidase_C	ACAD11 ACOX2	1.30e-03	16	63	2	IPR009075
Domain	UIM	STAM2 RBSN	2.95e-03	24	63	2	PS50330
Domain	EGF_CA	FAT1 FAT3 LDLR	3.07e-03	86	63	3	PF07645
Domain	UIM_dom	STAM2 RBSN	3.20e-03	25	63	2	IPR003903
Domain	-	FAT1 LMAN2L FAT3	4.06e-03	95	63	3	2.60.120.200
Domain	EGF_Ca-bd_CS	FAT1 FAT3 LDLR	4.30e-03	97	63	3	IPR018097
Domain	EGF_CA	FAT1 FAT3 LDLR	4.56e-03	99	63	3	PS01187
Domain	ASX_HYDROXYL	FAT1 FAT3 LDLR	4.69e-03	100	63	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT1 FAT3 LDLR	5.51e-03	106	63	3	IPR000152
Domain	LAM_G_DOMAIN	FAT1 FAT3	7.28e-03	38	63	2	PS50025
Domain	-	ELP1 LDLR	7.66e-03	39	63	2	2.120.10.30
Domain	Laminin_G_2	FAT1 FAT3	8.04e-03	40	63	2	PF02210
Domain	EGF_CA	FAT1 FAT3 LDLR	8.12e-03	122	63	3	SM00179
Domain	BROMODOMAIN_2	KMT2A TRIM24	8.44e-03	41	63	2	PS50014
Domain	EGF-like_Ca-bd_dom	FAT1 FAT3 LDLR	8.49e-03	124	63	3	IPR001881
Domain	BROMO	KMT2A TRIM24	8.84e-03	42	63	2	SM00297
Domain	Bromodomain	KMT2A TRIM24	8.84e-03	42	63	2	IPR001487
Domain	-	KMT2A TRIM24	8.84e-03	42	63	2	1.20.920.10
Domain	t-SNARE	STX4 AMOTL2	9.25e-03	43	63	2	IPR010989
Pathway	REACTOME_SIGNALING_BY_HIPPO	AMOT AMOTL1 AMOTL2	4.06e-05	20	48	3	MM14813
Pathway	REACTOME_SIGNALING_BY_HIPPO	AMOT AMOTL1 AMOTL2	4.06e-05	20	48	3	M591
Pubmed	NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.	NF2 AMOT AMOTL1 AMOTL2	2.62e-09	10	67	4	33058421
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CEP170 IPO5 NCOR1 RANBP2 AKAP9 NF2 AMOT ELP1 SPART CMYA5 PALLD	2.84e-09	497	67	11	23414517
Pubmed	Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains.	AMOT AMOTL1 AMOTL2	6.83e-09	3	67	3	12406577
Pubmed	Differential expression of the motin family in the peri-implantation mouse uterus and their hormonal regulation.	AMOT AMOTL1 AMOTL2	6.83e-09	3	67	3	22813598
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CEP170 NCOR1 STAM2 NF2 AMOT AMOTL1 KMT2A AMOTL2 ARID1A PALLD HTT	7.94e-09	549	67	11	38280479
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CEP170 AKAP9 LRCH2 ACAD11 NF2 AMOT AMOTL1 ELP1 AMOTL2 ARID1A	1.41e-08	446	67	10	24255178
Pubmed	The endothelial E3 ligase HECW2 promotes endothelial cell junctions by increasing AMOTL1 protein stability via K63-linked ubiquitination.	AMOT AMOTL1 AMOTL2	2.73e-08	4	67	3	27498087
Pubmed	Angiomotin regulates endothelial cell migration during embryonic angiogenesis.	AMOT AMOTL1 AMOTL2	2.73e-08	4	67	3	17699752
Pubmed	Angiomotin-like proteins associate with and negatively regulate YAP1.	AMOT AMOTL1 AMOTL2	2.73e-08	4	67	3	21187284
Pubmed	Angiomotin'g YAP into the nucleus for cell proliferation and cancer development.	AMOT AMOTL1 AMOTL2	2.73e-08	4	67	3	24003252
Pubmed	Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.	AMOT AMOTL1 AMOTL2	6.81e-08	5	67	3	21205866
Pubmed	The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.	NF2 AMOT AMOTL1 AMOTL2	8.96e-08	22	67	4	27521426
Pubmed	Angiomotin functions in HIV-1 assembly and budding.	AMOT AMOTL1 AMOTL2	1.36e-07	6	67	3	25633977
Pubmed	Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.	AMOT AMOTL1 AMOTL2	1.36e-07	6	67	3	17397395
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	IPO5 FAT1 NF2 AMOTL1 AMOTL2 ARID1A DNAH5 LDLR	2.53e-07	332	67	8	37433992
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	LRCH2 ACAD11 NF2 AMOT AMOTL1 AMOTL2 RASSF9	9.19e-07	270	67	7	24366813
Pubmed	Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.	IPO5 RANBP2 NUP107 KMT2A	1.09e-06	40	67	4	37516964
Pubmed	Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.	AMOT AMOTL1 AMOTL2	1.12e-06	11	67	3	28239148
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CEP170 IPO5 NCOR1 EXOC5 NUP107 WDR11 GOLIM4 ELP1 SPART	1.27e-06	560	67	9	35241646
Pubmed	Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.	NCOR1 LDLR HTT	3.06e-06	15	67	3	11092755
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	IPO5 STAM2 RANBP2 LMAN2L NUP107 KMT2A ARID1A YTHDC1	3.35e-06	469	67	8	27634302
Pubmed	Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton.	AMOT AMOTL1	3.66e-06	2	67	2	19565639
Pubmed	AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin.	NF2 AMOTL1	3.66e-06	2	67	2	26806348
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	AMOT AMOTL1 AMOTL2	3.76e-06	16	67	3	18824598
Pubmed	Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.	AMOT AMOTL1 AMOTL2 ARID1A	4.60e-06	57	67	4	38223760
Pubmed	Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis.	AMOT AMOTL1	1.10e-05	3	67	2	19590046
Pubmed	Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing.	YTHDC1 ALKBH5	1.10e-05	3	67	2	35190939
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT1 FAT3	1.10e-05	3	67	2	15744052
Pubmed	Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.	NCOR1 LDLR	1.10e-05	3	67	2	31529020
Pubmed	N6-Methyladenosine detected in RNA of testicular germ cell tumors is controlled by METTL3, ALKBH5, YTHDC1/F1/F2, and HNRNPC as writers, erasers, and readers.	YTHDC1 ALKBH5	1.10e-05	3	67	2	30903744
Pubmed	Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.	NCOR1 HTT	1.10e-05	3	67	2	12799135
Pubmed	Rho differentially regulates the Hippo pathway by modulating the interaction between Amot and Nf2 in the blastocyst.	NF2 AMOT	1.10e-05	3	67	2	28947533
Pubmed	Identification and characterization of a novel tight junction-associated family of proteins that interacts with a WW domain of MAGI-1.	AMOTL1 AMOTL2	1.10e-05	3	67	2	16019084
Pubmed	The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.	NF2 AMOT	1.10e-05	3	67	2	24003254
Pubmed	The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.	CEP170 AKAP9	1.10e-05	3	67	2	29054927
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	NF2 AMOTL1 AMOTL2	1.18e-05	23	67	3	26933062
Pubmed	The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.	AMOT AMOTL1 AMOTL2	1.52e-05	25	67	3	21145499
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	IPO5 NF2 AMOTL1 AMOTL2 ARID1A	1.58e-05	162	67	5	25796446
Pubmed	Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.	AMOT AMOTL1 AMOTL2	1.72e-05	26	67	3	28720576
Pubmed	Same but different - Molecular comparison of human KTI12 and PSTK.	RBSN AMOTL1 ELP1	1.93e-05	27	67	3	33417976
Pubmed	Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin.	NCOR1 HTT	2.19e-05	4	67	2	10441327
Pubmed	Early mouse development: lessons from gene targeting.	KMT2A HTT	2.19e-05	4	67	2	8791525
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	CEP170 RANBP2 LRCH2 NUP107 AMOT ELP1 ARID1A	2.24e-05	440	67	7	34244565
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	CEP170 NCOR1 RANBP2 SPART MTRR TRIM24 PALLD	2.37e-05	444	67	7	34795231
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	IVL RANBP2 NF2 AMOT AMOTL1 MYCBPAP	2.61e-05	302	67	6	30561431
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP170 NCOR1 TRIM24 LDLR PALLD	2.91e-05	184	67	5	32908313
Pubmed	OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.	NF2 AMOT AMOTL1 AMOTL2	2.96e-05	91	67	4	30472188
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NCOR1 STAM2 RANBP2 AKAP9 NUP107 NF2 WDR11 GOLIM4 ELP1 ARID1A	3.11e-05	1049	67	10	27880917
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CEP170 IPO5 NCOR1 ATP6V1E1 FAT1 LMAN2L GOLIM4 SPART ALKBH5 LDLR PALLD	3.51e-05	1297	67	11	33545068
Pubmed	The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.	NF2 ARID1A	3.64e-05	5	67	2	30401838
Pubmed	Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway.	NF2 AMOT	3.64e-05	5	67	2	26045165
Pubmed	RanGTP mediates nuclear pore complex assembly.	RANBP2 NUP107	3.64e-05	5	67	2	12894213
Pubmed	A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.	NF2 AMOT	3.64e-05	5	67	2	21481793
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	AMOT AMOTL1 SPART MTRR MRPL45 PALLD	3.73e-05	322	67	6	39098523
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	NCOR1 FAT1 AKAP9 LRCH2 AMOTL1 LPXN TRIM24 LDLR	5.31e-05	689	67	8	36543142
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	RANBP2 NUP107 CENPU KMT2A YTHDC1	5.45e-05	210	67	5	16565220
Pubmed	PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.	CEP170 IPO5 RANBP2 AMOT KMT2A	6.37e-05	217	67	5	31685992
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	CEP170 RANBP2 LRCH2 NUP107 AMOT SPART PALLD	7.59e-05	534	67	7	35032548
Pubmed	Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.	FAT1 FAT3	7.63e-05	7	67	2	22510986
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT1 FAT3	7.63e-05	7	67	2	16059920
Pubmed	Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation.	AMOT AMOTL2	7.63e-05	7	67	2	24225952
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NCOR1 RANBP2 NUP107 ARID1A	9.61e-05	123	67	4	26912792
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	RANBP2 ACAD11 NUP107 AMOT ELP1	9.64e-05	237	67	5	29564676
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	IPO5 RANBP2 STX4 LMAN2L NUP107 AMOT GOLIM4 YTHDC1 LDLR CYRIB	9.76e-05	1203	67	10	29180619
Pubmed	Proteomic analysis of mammalian primary cilia.	WDR11 CYRIB	1.02e-04	8	67	2	22326026
Pubmed	Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus.	NF2 AMOT	1.02e-04	8	67	2	25026211
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	NCOR1 RBSN FAT1 NUP107 NF2 WDR11 AMOT AMOTL1	1.22e-04	777	67	8	35844135
Pubmed	Cloning and characterization of human karyopherin beta3.	IPO5 RANBP2	1.30e-04	9	67	2	9114010
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	IPO5 NCOR1 RANBP2 ATP6V1E1 AKAP9 NUP107 NF2 AMOTL2 ARID1A YTHDC1	1.31e-04	1247	67	10	27684187
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOR1 STAM2 NUP107 ELP1 SPART ARID1A ALKBH5	1.38e-04	588	67	7	38580884
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	NCOR1 RANBP2 ACAD11 AMOT KMT2A ARID1A	1.43e-04	411	67	6	35182466
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	KMT2A ARID1A	1.63e-04	10	67	2	12665591
Pubmed	Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.	NCOR1 TRIM24	1.63e-04	10	67	2	30595551
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	CEP170 RANBP2 EXOC5 NUP107 WDR11 ELP1 SPART	1.66e-04	606	67	7	36538041
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	RBSN NAPG RASSF9	1.67e-04	55	67	3	18570454
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	IPO5 NF2 AMOT AMOTL1 AMOTL2 ARID1A PALLD	1.81e-04	615	67	7	31048545
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	STAM2 RANBP2 LMAN2L YTHDC1 PALLD HTT	2.11e-04	442	67	6	15815621
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	CEP170 IPO5 RBSN AKAP9	2.12e-04	151	67	4	17043677
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	EXOC5 AKAP9 AMOT HTT	2.17e-04	152	67	4	34299191
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	AMOTL1 SPART AMOTL2	2.38e-04	62	67	3	31340145
Pubmed	Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin.	PAG1 AKAP9	2.38e-04	12	67	2	17911601
Pubmed	Global landscape of HIV-human protein complexes.	CEP170 NCOR1 RANBP2 AKAP9 KIR3DL2 LDLR	2.53e-04	457	67	6	22190034
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	IPO5 WDR11 AMOT CENPU ELP1 SPART PALLD	2.61e-04	653	67	7	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CEP170 IPO5 RANBP2 NUP107 ELP1 KMT2A ARID1A	2.61e-04	653	67	7	22586326
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOR1 FAT1 STX4 LMAN2L NF2 LRRK1 ARID1A LDLR HTT	2.61e-04	1105	67	9	35748872
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	IVL CEP170 RANBP2 ATP6V1E1 GOLIM4 NAPG SPART ARID1A PALLD CYRIB	2.75e-04	1367	67	10	32687490
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	ELP1 KMT2A ARID1A	3.27e-04	69	67	3	28481362
Pubmed	Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway.	NF2 AMOTL2	3.28e-04	14	67	2	29183995
Pubmed	Defining the membrane proteome of NK cells.	IPO5 NCOR1 RANBP2 NUP107 NF2 WDR11 LPXN GOLIM4 LDLR	3.92e-04	1168	67	9	19946888
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	IPO5 RANBP2 ELP1 TRIM24	4.04e-04	179	67	4	36261009
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CEP170 IPO5 RANBP2 EXOC5 STX4 NAPG ELP1 KMT2A MRPL45 CYRIB	4.14e-04	1440	67	10	30833792
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	NCOR1 RANBP2 RBSN NUP107 YTHDC1 PALLD	4.20e-04	503	67	6	16964243
Pubmed	Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.	IPO5 NCOR1 FAT1 AMOT ELP1	4.58e-04	332	67	5	29053956
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	IPO5 KMT2A ARID1A HTT	4.67e-04	186	67	4	33637726
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP170 RANBP2 NF2 AMOT SPART MTRR PALLD	4.85e-04	724	67	7	36232890
Pubmed	A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.	AMOT AMOTL2	4.88e-04	17	67	2	16678097
Pubmed	AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions.	RANBP2 AMOT	4.88e-04	17	67	2	32391793
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	STAM2 EXOC5 AKAP9 NUP107 NF2 WDR11 ELP1 SPART MRPL45 TRIM24	5.33e-04	1487	67	10	33957083
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	CEP170 IPO5 AKAP9	5.43e-04	82	67	3	30274258
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOR1 ARID1A TRIM24	5.62e-04	83	67	3	28794006
Interaction	WWTR1 interactions	CEP170 NCOR1 STAM2 NF2 AMOT AMOTL1 KMT2A AMOTL2 ARID1A HTT	9.33e-07	422	65	10	int:WWTR1
Interaction	MAGEA3 interactions	IPO5 RANBP2 EXOC5 RBSN ACAD11 HTT	4.62e-06	134	65	6	int:MAGEA3
Interaction	RNF146 interactions	IPO5 NF2 AMOT AMOTL1 AMOTL2	4.93e-06	77	65	5	int:RNF146
Interaction	PARD3 interactions	STX4 NF2 AMOT AMOTL1 AMOTL2 RASSF9 HTT JAM2	5.06e-06	298	65	8	int:PARD3
Interaction	MYBPC2 interactions	RANBP2 NF2 AMOT CMYA5	1.33e-05	45	65	4	int:MYBPC2
Interaction	THRA interactions	NCOR1 AMOT AMOTL2 TRIM24 LDLR	2.94e-05	111	65	5	int:THRA
Interaction	SIRT6 interactions	CEP170 RANBP2 FAT1 LRCH2 NUP107 AMOT FAT3 ELP1 ARID1A PALLD	3.07e-05	628	65	10	int:SIRT6
Interaction	MEX3A interactions	IPO5 FAT1 NF2 AMOTL1 AMOTL2 ARID1A DNAH5 LDLR	3.16e-05	384	65	8	int:MEX3A
Interaction	USP9X interactions	CEP170 AMOT AMOTL1 ELP1 AMOTL2 ALKBH5 LDLR HTT	6.15e-05	422	65	8	int:USP9X
Interaction	LURAP1 interactions	EXOC5 NF2 AMOT AMOTL1 TRIM24	8.03e-05	137	65	5	int:LURAP1
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP9 NF2 CMYA5	3.52e-05	29	40	3	396
GeneFamily	Cadherin related	FAT1 FAT3	6.36e-04	17	40	2	24
GeneFamily	Nucleoporins	RANBP2 NUP107	2.27e-03	32	40	2	1051
Coexpression	GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP	IPO5 PKD2L2 FAT3 MRPL45 RASSF9 ADAM28	8.46e-06	187	67	6	M3287
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IVL ZAN FAT3 DNAH5 ADAM28	5.23e-06	169	66	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SCARF1 PKD2L2 PALLD ADAM28 JAM2	6.55e-06	177	66	5	c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MTRR C4BPA PLA2G4F DNAH5 LDLR	9.72e-06	192	66	5	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	COPD-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	IVL PAG1 RBSN RASSF9 LDLR	1.07e-05	196	66	5	af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	PAG1 FAT1 KMT2A ARID1A TRIM24	1.16e-05	199	66	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D175\|Adult / Lineage, Cell type, age group and donor	FAT1 AMOT DNAH5 LDLR	6.91e-05	148	66	4	012845b10850bbc67814da247ee5a69f6d631eaa
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	IPO5 FAT1 C4BPA DNAH5	7.28e-05	150	66	4	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PAG1 FAT1 FAT3 CMYA5	8.69e-05	157	66	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	AMOTL1 CENPU GOLIM4 KIR3DL2	1.00e-04	163	66	4	466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ENAM LRRK1 ADAM28 CYRIB	1.05e-04	165	66	4	d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF1 LMAN2L ZAN JAM2	1.13e-04	168	66	4	3bddf411a60137a8883fc9e77586e4719b0d6067
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF1 LMAN2L ZAN JAM2	1.13e-04	168	66	4	b6d948857ee652351ddbe383b75fdd1721cd8721
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRCH2 FAT3 AMOTL1 PALLD	1.18e-04	170	66	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	RASSF9 CMYA5 DNAH5 MYCBPAP	1.21e-04	171	66	4	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AMOTL2 RASSF9 ADAM28 ACOX2	1.24e-04	172	66	4	5401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AMOTL2 RASSF9 ADAM28 ACOX2	1.24e-04	172	66	4	b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AMOTL2 RASSF9 ADAM28 ACOX2	1.24e-04	172	66	4	74dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FAT1 C4BPA RASSF9 DNAH5	1.38e-04	177	66	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SCARF1 PKD2L2 ADAM28 JAM2	1.38e-04	177	66	4	3a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ENAM LRRK1 ADAM28 CYRIB	1.38e-04	177	66	4	c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	SCARF1 AMOT C4BPA SH3D21	1.50e-04	181	66	4	cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCARF1 ZAN RASSF9 JAM2	1.54e-04	182	66	4	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 ZAN FAT3 DNAH5	1.60e-04	184	66	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 ZAN FAT3 DNAH5	1.60e-04	184	66	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 ZAN FAT3 DNAH5	1.60e-04	184	66	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR1 RANBP2 AKAP9 YTHDC1	1.70e-04	187	66	4	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 PAG1 KMT2A LDLR	1.74e-04	188	66	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SCARF1 ATP6V1E1 PALLD SH3D21	1.74e-04	188	66	4	762b52f21d2bc5409f86746a904c4358490be9c0
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GOLIM4 LRRK1 PALLD ADAM28	1.74e-04	188	66	4	9fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GOLIM4 LRRK1 PALLD ADAM28	1.74e-04	188	66	4	5e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	IPO5 CENPU AMOTL2 ZNF367	1.77e-04	189	66	4	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FAT1 RASSF9 DNAH5 ADAM28	1.81e-04	190	66	4	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FAT1 CMYA5 PALLD CYRIB	1.81e-04	190	66	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH5 MYCBPAP ADAM28 ACOX2	1.81e-04	190	66	4	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH5 MYCBPAP ADAM28 ACOX2	1.81e-04	190	66	4	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PAG1 FAT3 CENPU ZNF367	1.81e-04	190	66	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	COVID-19-Myeloid-DC2\|COVID-19 / Condition, Lineage and Cell class	AMOT LRRK1 PALLD ADAM28	1.85e-04	191	66	4	1304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH5 MYCBPAP ADAM28 ACOX2	1.85e-04	191	66	4	6a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCARF1 AMOTL1 AMOTL2 JAM2	1.88e-04	192	66	4	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 PAG1 KMT2A LDLR	1.88e-04	192	66	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCARF1 AMOTL1 AMOTL2 JAM2	1.88e-04	192	66	4	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCARF1 AMOTL1 AMOTL2 JAM2	1.88e-04	192	66	4	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RANBP2 EXOC5 AKAP9 ARID1A	1.92e-04	193	66	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	ASK440-Epithelial-Secretory\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	RASSF9 DNAH5 PALLD ADAM28	1.92e-04	193	66	4	50e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LRRK1 ADAM28 SH3D21 CYRIB	1.96e-04	194	66	4	5a048bd2af30975fdc57ff40bc49aa5811c830d8
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PAG1 FAT1 FAT3 ADAM28	1.96e-04	194	66	4	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCARF1 AMOTL1 AMOTL2 JAM2	2.00e-04	195	66	4	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR1 AKAP9 KMT2A LDLR	2.00e-04	195	66	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IVL FAT1 RASSF9 ADAM28	2.00e-04	195	66	4	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOR1 AKAP9 KMT2A LDLR	2.00e-04	195	66	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	MTRR C4BPA PLA2G4F LDLR	2.08e-04	197	66	4	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	ASK440-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	MTRR C4BPA PLA2G4F LDLR	2.08e-04	197	66	4	08d5bbeb77a4152af1c783bc958afcae24667767
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MTRR C4BPA PLA2G4F LDLR	2.08e-04	197	66	4	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FAT1 FAT3 AMOTL2 PALLD	2.12e-04	198	66	4	55d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PKD2L2 FAT3 CMYA5 PALLD	2.12e-04	198	66	4	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CEP170 AKAP9 MRPL45 TRIM24	2.12e-04	198	66	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FAT1 FAT3 AMOTL2 PALLD	2.12e-04	198	66	4	8602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	AKAP9 FAT3 GOLIM4 PALLD	2.16e-04	199	66	4	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	AKAP9 NAPG MRPL45 DNAH5	2.16e-04	199	66	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IVL RASSF9 DNAH5 ADAM28	2.16e-04	199	66	4	2b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Club\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	IVL RASSF9 DNAH5 ADAM28	2.16e-04	199	66	4	111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IVL RASSF9 DNAH5 ADAM28	2.16e-04	199	66	4	d583290a1d288b749ad17bc501c1487268c6551c
ToppCell	TCGA-Cervix-Primary_Tumor\|TCGA-Cervix / Sample_Type by Project: Shred V9	ZDHHC12 CENPU CYRIB ZNF367	2.16e-04	199	66	4	ef6fde26af2ca9e6cde198ac0e14e03d9ab398f8
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FAT1 AKAP9 TRIM24 LDLR	2.20e-04	200	66	4	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	proximal-3-Epithelial-Alveolar_Epithelial_Type_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MTRR C4BPA PLA2G4F LDLR	2.20e-04	200	66	4	e1ede812cd2ff65af63d2fd85145ad1e0049468f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-OPC_related-Oligodendrocyte/OPC\|3m / Sample Type, Dataset, Time_group, and Cell type.	GOLIM4 DMRTA1 AMOTL2 JAM2	2.20e-04	200	66	4	7557ea33c3d080d0fa4ca0c2703279932d01e6d0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-OPC_related\|3m / Sample Type, Dataset, Time_group, and Cell type.	GOLIM4 DMRTA1 AMOTL2 JAM2	2.20e-04	200	66	4	3dcaeb9f1e387784c299bfe0da1516598f82edf5
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AKAP9 KMT2A YTHDC1 KIR3DL2	2.20e-04	200	66	4	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	proximal-Epithelial-Alveolar_Epithelial_Type_2\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MTRR C4BPA PLA2G4F LDLR	2.20e-04	200	66	4	685bf05615688a1668ba6756d1ba77dff200faf9
ToppCell	proximal-Epithelial-Alveolar_Epithelial_Type_2-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MTRR C4BPA PLA2G4F LDLR	2.20e-04	200	66	4	0780490f262115bd8feb6302feae2e398aa67e92
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PKD2L2 HFM1 MYCBPAP	2.46e-04	82	66	3	01a4d47d9e0dee68a5277ed1534338cec80f75d1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PKD2L2 HFM1 MYCBPAP	2.46e-04	82	66	3	c1489097c291f413f3cfa5e26f8182ec872328fd
Computational	Neighborhood of UBE2N	CEP170 EXOC5 NF2 ELP1 KMT2A ARID1A YTHDC1	2.66e-06	154	44	7	GCM_UBE2N
Computational	Neighborhood of DENR	IPO5 ACAD11 NF2 ALKBH5	4.90e-05	50	44	4	GCM_DENR
Computational	Neighborhood of DFFA	IPO5 EXOC5 ELP1 KMT2A ARID1A	1.72e-04	129	44	5	GCM_DFFA
Computational	Neighborhood of SUFU	CEP170 EXOC5 ELP1 KMT2A	2.66e-04	77	44	4	GCM_SUFU
Computational	Genes upregulated in subsets of cells of a given type within various tumors	RANBP2 GOLIM4 KMT2A	1.10e-03	50	44	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Computational	Neighborhood of ZNF198	CEP170 EXOC5 ELP1 ARID1A	1.29e-03	117	44	4	GCM_ZNF198
Computational	Neighborhood of NF2	IPO5 ACAD11 NF2 NAPG KMT2A ALKBH5	1.34e-03	302	44	6	GCM_NF2
Computational	Neighborhood of IL6ST	IPO5 ACAD11 NAPG	1.45e-03	55	44	3	GCM_IL6ST
Disease	cardiovascular disease biomarker measurement, ankle brachial index	FAT3 DNAH5	4.91e-05	5	66	2	EFO_0003912, EFO_0005278
Disease	meningioma (is_implicated_in)	NF2 MTRR	7.35e-05	6	66	2	DOID:3565 (is_implicated_in)
Disease	metabolic syndrome	STAM2 KMT2A DMRTA1 ARID1A LDLR	8.69e-05	200	66	5	EFO_0000195
Disease	Carcinoma, Transitional Cell	NCOR1 KMT2A ARID1A	1.07e-04	41	66	3	C0007138
Disease	Prostatic Cancer, Castration-Resistant	TRIM24 ZNF367	1.76e-04	9	66	2	C3658266
Disease	Prostatic Neoplasms, Castration-Resistant	TRIM24 ZNF367	1.76e-04	9	66	2	C3658267
Disease	L2 Acute Lymphoblastic Leukemia	PAG1 MTRR KMT2A	1.94e-04	50	66	3	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	PAG1 MTRR KMT2A	2.18e-04	52	66	3	C0023452
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	PAG1 MTRR KMT2A	3.51e-04	61	66	3	C1961102
Disease	Adenocarcinoma Of Esophagus	SPART ARID1A	4.41e-04	14	66	2	C0279628
Disease	non-Hodgkin lymphoma (is_implicated_in)	MTRR KMT2A	6.56e-04	17	66	2	DOID:0060060 (is_implicated_in)
Disease	cytotoxicity measurement, response to metformin	STX4 GOLIM4	1.01e-03	21	66	2	EFO_0006952, GO_1901558
Disease	otitis media (implicated_via_orthology)	NF2 DNAH5	1.11e-03	22	66	2	DOID:10754 (implicated_via_orthology)
Disease	longevity, healthspan, parental longevity	LDLR HTT	1.92e-03	29	66	2	EFO_0004300, EFO_0007796, EFO_0009762

Protein segments in the cluster

Peptide	Gene	Start	Entry
QSYEQQQEQEKLERE	AMOTL2	426	Q9Y2J4
VDKDQYVEPENVTIQ	C4BPA	496	P04003
VDDNQDYNRPVINEK	CEP170	526	Q5SW79
ETPTQVYQKDKQDAD	CEP170	681	Q5SW79
SDPEAKVLDYQTQQQ	ACOX2	331	Q99424
EQESEKPSQELLEYN	AKAP9	3111	Q99996
QNNEELPTYEEAKVQ	AMOT	101	Q4VCS5
EPEQQEQFETELKYK	ADAM28	46	Q9UKQ2
PERSDYEEQQLQKEE	ALKBH5	66	Q6P6C2
QDYSDVQAQEPNVKE	CENPU	366	Q71F23
PQQNNEELPTYEEAK	AMOTL1	181	Q8IY63
ENQDQQEPKPYSDDD	CDC14C	376	A4D256
PAEKEVTEFYVQNEN	ACAD11	396	Q709F0
SEVEQNLDLQYEENQ	RASSF9	241	O75901
NDALSPEEQEECKNY	RANBP2	696	P49792
QLQDEYDQQQTEKAI	RBSN	491	Q9H1K0
PQDSIAEIYNQCEEQ	NUP107	716	P57740
QDSDEQDPQEVTYAQ	KIR3DL2	386	P43630
QAPLTYEKEEEQDQG	ARID1A	2026	O14497
DIQEFPNYEVIDEQT	FAT1	4396	Q14517
EQLVEQTPDNDIKDY	LRRK1	876	Q38SD2
QTPDNDIKDYEDLQS	LRRK1	881	Q38SD2
AAEGLEPKYQVQEQE	PPP1R2P1	106	Q96PQ5
GEEEAPAKYVQDNIQ	MTRR	616	Q9UBK8
QDKQEDPTNEKSQNY	FAM214A	746	Q32MH5
QEFYAEQKQQIEPGE	EEF1AKMT1	21	Q8WVE0
EQKQQIEPGEDDKYN	EEF1AKMT1	26	Q8WVE0
IQELNVYSEAQEPKE	LPXN	66	O60711
VFVDTYPNEEKQQER	LMAN2L	156	Q9H0V9
YKIQFENNEDQDVNP	ELP1	486	O95163
APKDQQVVTAVEYQE	JAM2	31	P57087
PDNVVRKQAEETYEN	IPO5	21	O00410
YQEENPAKLSDQQEA	PLA2G4F	471	Q68DD2
YPENAEEELVQEITQ	NF2	101	P35240
QIDIAEVEQYGPQEN	PASD1	241	Q8IV76
NPDQQEDNVDEQYQE	GOLIM4	601	O00461
PSEYQDKEVLNVNFE	HFM1	1251	A2PYH4
NIQEPEEETANQEYK	PALLD	946	Q8WX93
DQLQQEEPPIESQDY	PAGE3	36	Q5JUK9
KPEDENNVLIQYTNA	EXOC5	561	O00471
EEEEEVDPNTQNPKY	HTT	2341	P42858
PQDDQEVNELVEEYR	CMYA5	3746	Q8N3K9
EVFQQDYPEEKQEQK	DMRTA1	211	Q5VZB9
DENDNKPQFPEKVYQ	FAT3	1246	Q8TDW7
YNPNDEEEEEVQLKS	KMT2A	3791	Q03164
AQPTESEKEIYNQVN	CYRIB	26	Q9NUQ9
NTPDQKEIVPYNEED	ENAM	641	Q9NRM1
FQNLEQEINAEPEYV	DNAH5	1176	Q8TE73
DSQKDQEVYDFVDPN	LRCH2	396	Q5VUJ6
PETVYKGQQDQIDQD	MINDY2	501	Q8NBR6
PQNYTENKNEGVDVT	SH3D21	561	A4FU49
EEYEEAQGEAQKPQL	MRPL45	291	Q9BRJ2
TYQPEVVKANQAEND	NCOR1	1991	O75376
PQKEEADENYNSVNT	STX4	106	Q12846
EEYQKAENPEQQLKQ	IVL	96	P07476
VPKENDYESISDLQQ	PAG1	411	Q9NWQ8
KQAEEERQEEPEYEN	SCARF1	806	Q14162
KQESDEESRPQNANY	TRIM24	741	O15164
EDYQIVDNSQRENQE	SPART	626	Q8N0X7
ENVDPEKAVQLYQQT	NAPG	126	Q99747
EKETIYLNVPEEQDQ	MYCBPAP	796	Q8TBZ2
ANPFEQDVEKATNEY	STAM2	6	O75886
IQDDYQPVTQEEFRE	PKD2L2	581	Q9NZM6
QDDELYNPESEQDKN	YTHDC1	26	Q96MU7
NDVDVQIDQESYLPE	ATP6V1E1	161	P36543
YVNVQPQPQEELKEE	ZDHHC12	71	Q96GR4
KADQEQQDPLEYLQS	ZNF367	296	Q7RTV3
DYPENEEIKNLLQEQ	WDR11	876	Q9BZH6
YLEQQQDETKQAQEE	TRAIP	141	Q9BWF2
EDQECQKYQVVNSPS	ZAN	1326	Q9Y493
INFDNPVYQKTTEDE	LDLR	821	P01130