Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsteroid 11-beta-monooxygenase activity

CYP11B1 CYP11B2

4.54e-0521352GO:0004507
GeneOntologyMolecularFunctioncorticosterone 18-monooxygenase activity

CYP11B1 CYP11B2

4.54e-0521352GO:0047783
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A3 SLC46A1 GRIK3 SLC16A12 SLC16A1 ABCD1 GRIN3B SLC38A3

8.37e-052071358GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A3 SLC46A1 GRIK3 SLC16A12 SLC16A1 ABCD1 GRIN3B SLC38A3

8.66e-052081358GO:0005342
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 ADCY6 GUCY2C

2.29e-04181353GO:0004016
GeneOntologyMolecularFunctionsteroid binding

NPC1 CYP11B1 CYP11B2 IGF1 RORC PAQR7

2.90e-041331356GO:0005496
GeneOntologyMolecularFunctioncyclase activity

NPR1 ADCY6 GUCY2C

5.51e-04241353GO:0009975
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC46A1 SLC16A1 SLC2A13

6.23e-04251353GO:0015295
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

NPR1 ADCY6 GUCY2C

6.23e-04251353GO:0016849
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A3 SLC46A1 GRIK3 SLC16A12 SLC16A1 ABCD1 GRIN3B SLC38A3

8.66e-042931358GO:0008514
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2A14 NPR1 OXER1 SIGMAR1 OR5T2 OR2A5 OR2J2 GRIK3 SUCNR1 ADGRG4 OR5AL1 OR8B8 CELSR2 OR56B4 GP1BA

9.51e-0488413515GO:0004930
GeneOntologyBiologicalProcesschemical homeostasis

NPC1 LPCAT1 NPR1 SLC26A3 CYP11B1 CYP11B2 SREBF2 SLC46A1 SUCNR1 TM6SF2 ADCY6 ACOX2 OTC THADA IGF1 SLC16A1 PLCH2 TRPV6 ABCD1 TRPV5 SLC38A3 GP1BA

1.56e-05124913322GO:0048878
GeneOntologyCellularComponentt-UTP complex

NOL11 HEATR1

1.27e-0431372GO:0034455
MousePhenodecreased circulating renin level

NPR1 CYP11B1 CYP11B2 SUCNR1

6.58e-07101074MP:0003353
MousePhenodecreased lipid level

NPC1 TTC28 CDK15 CYP11B1 CYP11B2 SREBF2 WDR27 TM6SF2 ZZEF1 LIPE TXNDC5 AEBP1 SLC16A1 ATAD2B PCDH15 PNPLA7 GRIN3B

3.53e-0572710717MP:0014461
MousePhenoabnormal urine progesterone level

CYP11B1 CYP11B2

5.80e-0521072MP:0011545
MousePhenoabnormal urine deoxycorticosterone level

CYP11B1 CYP11B2

5.80e-0521072MP:0011552
MousePhenodecreased urine corticosterone level

CYP11B1 CYP11B2

5.80e-0521072MP:0011550
MousePhenoincreased urine deoxycorticosterone level

CYP11B1 CYP11B2

5.80e-0521072MP:0011553
MousePhenoincreased urine progesterone level

CYP11B1 CYP11B2

5.80e-0521072MP:0011546
MousePhenoabnormal circulating renin level

NPR1 CYP11B1 CYP11B2 SUCNR1

6.65e-05291074MP:0003349
MousePhenoabnormal potassium level

SLC26A3 CYP11B1 CYP11B2 SLC46A1 ZZEF1 ADCY6 TFCP2L1 GRIN3B

1.29e-041961078MP:0020887
MousePhenoabnormal potassium ion homeostasis

SLC26A3 CYP11B1 CYP11B2 SLC46A1 ZZEF1 ADCY6 TFCP2L1 GRIN3B

1.38e-041981078MP:0011978
MousePhenoabnormal circulating mineralocorticoid level

NPR1 SLC26A3 CYP11B1 CYP11B2

1.96e-04381074MP:0003372
MousePhenoabnormal circulating aldosterone level

NPR1 SLC26A3 CYP11B1 CYP11B2

1.96e-04381074MP:0005346
MousePhenoabnormal aldosterone level

NPR1 SLC26A3 CYP11B1 CYP11B2

2.64e-04411074MP:0011415
MousePhenoabnormal adrenal gland zona glomerulosa morphology

CYP11B1 CYP11B2

3.45e-0441072MP:0008293
MousePhenodecreased urine aldosterone level

CYP11B1 CYP11B2

3.45e-0441072MP:0011541
MousePhenoabnormal urine aldosterone level

CYP11B1 CYP11B2

3.45e-0441072MP:0011539
MousePhenoabnormal urine corticosterone level

CYP11B1 CYP11B2

3.45e-0441072MP:0011548
MousePhenodecreased urine hormone level

CYP11B1 CYP11B2

3.45e-0441072MP:0014459
MousePhenoabnormal axon guidance

EPHB2 B4GAT1 DCC PRDM8

3.80e-04451074MP:0002961
MousePhenoabnormal adrenal gland zona fasciculata morphology

CYP11B1 CYP11B2 ABCD1

3.86e-04191073MP:0008294
DomainCyt_P450_mitochondrial

CYP11B1 CYP11B2

5.11e-0521342IPR002399
DomainTRPV5/TRPV6

TRPV6 TRPV5

5.11e-0521342IPR008344
DomainARM-type_fold

GBF1 NBEAL1 MROH5 ZNFX1 HEATR1 DOCK5 RIF1 THADA HEATR6 NOC4L

1.70e-0433913410IPR016024
DomainPeripla_BP_I

NPR1 GRIK3 GUCY2C GRIN3B

1.71e-04391344IPR028082
DomainA/G_cyclase_CS

NPR1 ADCY6 GUCY2C

2.28e-04171343IPR018297
Domain-

NPR1 ADCY6 GUCY2C

2.72e-041813433.30.70.1230
DomainNucleotide_cyclase

NPR1 ADCY6 GUCY2C

2.72e-04181343IPR029787
DomainGuanylate_cyc

NPR1 ADCY6 GUCY2C

3.22e-04191343PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 ADCY6 GUCY2C

3.22e-04191343PS50125
DomainA/G_cyclase

NPR1 ADCY6 GUCY2C

3.22e-04191343IPR001054
DomainGUANYLATE_CYCLASE_1

NPR1 ADCY6 GUCY2C

3.22e-04191343PS00452
DomainCYCc

NPR1 ADCY6 GUCY2C

3.22e-04191343SM00044
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

NPC1 GBF1 SREBF2 RTN3 CERS6 NECTIN3 PRPF8 SERPINH1 ADCY6 TGOLN2 TXNDC5 ERGIC3 COG1 SLC16A1 ICMT SEC24B TMEM131 CLEC16A SLC38A3

7.19e-099521371938569033
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

EPHB2 LPCAT1 GBF1 SIGMAR1 NOL11 RTN3 DTX3L HEATR1 PRPF8 SERPINH1 EPM2AIP1 RIF1 TXNDC5 ERGIC3 SLC16A1 ICMT MRC2 NUP210 LOXL4 NOC4L ABCD1

1.12e-0812031372129180619
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EPHB2 NPC1 NPR1 B4GAT1 SIGMAR1 CD109 RTN3 CERS6 NECTIN3 ZZEF1 SERPINH1 TGOLN2 THADA TXNDC5 ERGIC3 CELSR2 MRC2 NUP210 TMEM131 CHPF

5.59e-0812011372035696571
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NPC1 LPCAT1 SIGMAR1 SREBF2 RTN3 CERS6 HEATR1 SERPINH1 THADA PDE12 MTX2 COG1 SLC16A1 NUP210 SEC24B ABCD1 CHPF

1.98e-079421371731073040
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

GBF1 DHX57 MYO1B ZNFX1 PRPF8 DOCK5 HEATR6 NUP210

1.48e-06202137833005030
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SPTBN2 NOL11 DHX57 MYO1B HEATR1 PRPF8 SERPINH1 RIF1 UTP15 ATAD2B NUP210 NOC4L KDM1A

2.04e-066531371322586326
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

LPCAT1 GBF1 SIGMAR1 RTN3 HEATR1 PRPF8 ZZEF1 RIF1 THADA MTX2 ERGIC3 SLC16A1 NUP210

2.18e-066571371336180527
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

NPC1 NPR1 CD109 MRC2 NUP210 LOXL4 DNAH5 KDM6A

2.28e-06214137822199357
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

NPC1 CD109 ERGIC3 NUP210 TMEM131 ABCD1 CHPF

4.19e-06164137732409323
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

EPHB2 GBF1 B4GAT1 SIGMAR1 COQ8B SLC46A1 NECTIN3 ADCY6 TGOLN2 DOCK5 RIF1 THADA CELSR2 COG1 MRC2 TARBP2

4.72e-0610611371633845483
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SPTBN2 COQ8B HIC2 LRRC70 PRPF8 ZZEF1 DOCK5 OTC PDE12 ATAD2B CEP295 EEF1AKMT1 GP1BA

7.42e-067361371329676528
Pubmed

Gene targeting approaches to analyzing hypertension.

NPR1 CYP11B1 CYP11B2

9.64e-0611137310405217
Pubmed

Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.

NPC1 THADA IGF1 CELSR2 STK33

1.22e-0575137520571754
Pubmed

Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.

CYP11B1 CYP11B2

1.54e-052137223150505
Pubmed

GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

1.54e-052137235012455
Pubmed

Role of genetic variation in regulation of aldosterone biosynthesis.

CYP11B1 CYP11B2

1.54e-052137221164264
Pubmed

Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.

TRPV6 TRPV5

1.54e-052137220178461
Pubmed

The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.

TRPV6 TRPV5

1.54e-052137222354706
Pubmed

Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.

TRPV6 TRPV5

1.54e-052137216564089
Pubmed

Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.

TRPV6 TRPV5

1.54e-052137219295174
Pubmed

Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.

TRPV6 TRPV5

1.54e-052137223968883
Pubmed

Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.

TRPV6 TRPV5

1.54e-052137212390878
Pubmed

The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.

CYP11B1 CYP11B2

1.54e-05213728645611
Pubmed

Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.

CYP11B1 CYP11B2

1.54e-052137212231255
Pubmed

TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.

TRPV6 TRPV5

1.54e-052137230916584
Pubmed

A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.

CYP11B1 CYP11B2

1.54e-052137220634641
Pubmed

Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.

CYP11B1 CYP11B2

1.54e-05213721303253
Pubmed

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

TRPV6 TRPV5

1.54e-052137216565876
Pubmed

Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.

CYP11B1 CYP11B2

1.54e-05213721741400
Pubmed

CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota.

CD109 RORC

1.54e-052137231597099
Pubmed

Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.

CYP11B1 CYP11B2

1.54e-052137232540969
Pubmed

Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.

TRPV6 TRPV5

1.54e-052137216705151
Pubmed

Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.

CYP11B1 CYP11B2

1.54e-052137226047574
Pubmed

Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.

CYP11B1 CYP11B2

1.54e-052137226324851
Pubmed

Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.

CYP11B1 CYP11B2

1.54e-05213727669222
Pubmed

Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.

CYP11B1 CYP11B2

1.54e-052137222933298
Pubmed

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

NPC1 SREBF2

1.54e-052137217008555
Pubmed

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.

CYP11B1 CYP11B2

1.54e-05213722783417
Pubmed

Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.

CYP11B1 CYP11B2

1.54e-05213722256920
Pubmed

Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.

TRPV6 TRPV5

1.54e-052137220405023
Pubmed

A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.

TRPV6 TRPV5

1.54e-052137211846401
Pubmed

Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.

CYP11B1 CYP11B2

1.54e-052137220708777
Pubmed

Molecular genetic studies on the biosynthesis of aldosterone in humans.

CYP11B1 CYP11B2

1.54e-052137222217843
Pubmed

Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.

CYP11B1 CYP11B2

1.54e-052137216396990
Pubmed

Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.

TRPV6 TRPV5

1.54e-052137224761864
Pubmed

pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.

SUCNR1 SLC16A1

1.54e-052137232946811
Pubmed

[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.

CYP11B1 CYP11B2

1.54e-052137218397978
Pubmed

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.

CYP11B1 CYP11B2

1.54e-05213721518866
Pubmed

Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.

TRPV6 TRPV5

1.54e-052137212077127
Pubmed

Differences in the amount of lipolysis induced by atrial natriuretic peptide in small and large adipocytes.

NPR1 LIPE

1.54e-052137218383440
Pubmed

Procollagen I-expressing renin cell precursors.

CYP11B1 CYP11B2

1.54e-052137223761669
Pubmed

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).

CYP11B1 CYP11B2

1.54e-05213722592361
Pubmed

Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.

CYP11B1 CYP11B2

1.54e-052137223314847
Pubmed

Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.

CYP11B1 CYP11B2

1.54e-052137217980006
Pubmed

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

CYP11B1 CYP11B2

1.54e-052137216984984
Pubmed

Evidence for local aldosterone synthesis in the large intestine of the mouse.

CYP11B1 CYP11B2

1.54e-052137235288482
Pubmed

Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.

CYP11B1 CYP11B2

1.54e-052137215731365
Pubmed

[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].

TRPV6 TRPV5

1.54e-052137224592736
Pubmed

Myosin 1b functions as an effector of EphB signaling to control cell repulsion.

EPHB2 MYO1B

1.54e-052137226195670
Pubmed

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

CYP11B1 CYP11B2

1.54e-052137217651452
Pubmed

Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.

CYP11B1 CYP11B2

1.54e-052137234743356
Pubmed

Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.

CYP11B1 CYP11B2

1.54e-052137220339375
Pubmed

High salt intake increases uroguanylin expression in mouse kidney.

NPR1 GUCY2C

1.54e-052137211416031
Pubmed

Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.

CYP11B1 CYP11B2

1.54e-052137220808686
Pubmed

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

TRPV6 TRPV5

1.54e-052137212574114
Pubmed

Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.

TRPV6 TRPV5

1.54e-052137211549322
Pubmed

[TRPV5 and TRPV6 calcium channels in human T cells].

TRPV6 TRPV5

1.54e-052137219140341
Pubmed

Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.

CYP11B1 CYP11B2

1.54e-052137221519965
Pubmed

Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.

CYP11B1 CYP11B2

1.54e-052137221625068
Pubmed

Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.

CYP11B1 CYP11B2

1.54e-052137216110193
Pubmed

Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.

CYP11B1 CYP11B2

1.54e-052137226066897
Pubmed

Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.

CYP11B1 CYP11B2

1.54e-052137218651133
Pubmed

A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.

CYP11B1 CYP11B2

1.54e-052137222083159
Pubmed

Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.

CYP11B1 CYP11B2

1.54e-052137215699546
Pubmed

Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.

CYP11B1 CYP11B2

1.54e-052137218162527
Pubmed

Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.

CYP11B1 CYP11B2

1.54e-052137238341019
Pubmed

First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.

TRPV6 TRPV5

1.54e-052137225164318
Pubmed

Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.

CYP11B1 CYP11B2

1.54e-052137224837548
Pubmed

Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.

CYP11B1 CYP11B2

1.54e-052137230046010
Pubmed

Familial and phenotypic associations of the aldosterone Renin ratio.

CYP11B1 CYP11B2

1.54e-052137219820005
Pubmed

Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

TRPV6 TRPV5

1.54e-052137215123711
Pubmed

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

CYP11B1 CYP11B2

1.54e-052137222622494
Pubmed

Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.

CYP11B1 CYP11B2

1.54e-052137215062555
Pubmed

Akt acutely activates the cholesterogenic transcription factor SREBP-2.

SREBF2 IGF1

1.54e-052137222005015
Pubmed

Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.

CYP11B1 CYP11B2

1.54e-052137217075030
Pubmed

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.

CYP11B1 CYP11B2

1.54e-052137217075029
Pubmed

CYP11B2-CYP11B1 haplotypes associated with decreased 11 beta-hydroxylase activity.

CYP11B1 CYP11B2

1.54e-052137215507509
Pubmed

Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.

TRPV6 TRPV5

1.54e-052137211719848
Pubmed

Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.

TRPV6 TRPV5

1.54e-052137217233615
Pubmed

Polymorphism of CYP11B2 determines salt sensitivity in Japanese.

CYP11B1 CYP11B2

1.54e-052137217296872
Pubmed

Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.

CYP11B1 CYP11B2

1.54e-052137218039983
Pubmed

Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.

CYP11B1 CYP11B2

1.54e-052137219029289
Pubmed

Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.

CYP11B1 CYP11B2

1.54e-052137215522937
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SPTBN2 NOL11 WDR27 DHX57 HEATR1 PRPF8 EPM2AIP1 MTX2 UTP15 NOC4L CHPF TARBP2

3.50e-057321371234732716
Pubmed

The roles of cAMP and cAMP-dependent protein kinase in the expression of cholesterol side chain cleavage and steroid 11 beta-hydroxylase genes in mouse adrenocortical tumor cells.

CYP11B1 CYP11B2

4.61e-05313722546938
Pubmed

Kidney function in mice lacking aldosterone.

CYP11B1 CYP11B2

4.61e-053137216118390
Pubmed

Aldosterone-induced coronary dysfunction in transgenic mice involves the calcium-activated potassium (BKCa) channels of vascular smooth muscle cells.

CYP11B1 CYP11B2

4.61e-053137217984374
Pubmed

Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11 beta-hydroxylase.

CYP11B1 CYP11B2

4.61e-05313722233742
Pubmed

Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system.

CYP11B1 CYP11B2

4.61e-053137233271253
Pubmed

The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene.

CYP11B1 CYP11B2

4.61e-053137218801336
InteractionGPR182 interactions

LPCAT1 GBF1 SIGMAR1 COQ8B SREBF2 HEATR1 DOCK5 RIF1 THADA LIPE HEATR6 ERGIC3 COG1 ICMT ABCD1

2.80e-0745513115int:GPR182
InteractionMFSD4A interactions

LPCAT1 GBF1 SIGMAR1 COQ8B HEATR1 RIF1 THADA MTX2 COG1 ICMT

2.19e-0622513110int:MFSD4A
InteractionCD70 interactions

NPC1 GBF1 COQ8B NOL11 HEATR1 ADCY6 TGOLN2 THADA

1.31e-051661318int:CD70
InteractionNPTN interactions

GBF1 TTC28 NBEAL1 COQ8B HEATR1 TGOLN2 THADA HEATR6 COG1 NOC4L

1.41e-0527813110int:NPTN
InteractionALG3 interactions

SIGMAR1 TMEM52B TGOLN2 ERGIC3 NIPAL1

1.47e-05481315int:ALG3
InteractionMGARP interactions

GBF1 COQ8B HEATR1 RIF1 THADA HEATR6 MTX2 STK33 ABCD1

1.50e-052221319int:MGARP
InteractionP2RY8 interactions

NPC1 GBF1 SIGMAR1 COQ8B HEATR1 RIF1 THADA MTX2

2.26e-051791318int:P2RY8
InteractionGPR84 interactions

SIGMAR1 CERS6 THADA COG1

2.28e-05261314int:GPR84
InteractionCHRM4 interactions

GBF1 CERS6 RIF1 THADA ERGIC3 COG1

3.43e-05941316int:CHRM4
InteractionLRRC31 interactions

GBF1 DHX57 MYO1B ZNFX1 PRPF8 DOCK5 HEATR6 NUP210

5.94e-052051318int:LRRC31
InteractionBSG interactions

NPC1 GBF1 TTC28 MYO1B HEATR1 PRPF8 TGOLN2 DOCK5 RIF1 HEATR6 COG1 SLC16A1 STK33 ABCD1

6.34e-0563113114int:BSG
InteractionLMAN2L interactions

NPC1 B4GAT1 CERS6 TGOLN2 MRC2 TMEM131

8.71e-051111316int:LMAN2L
InteractionTMEM41B interactions

SREBF2 HEATR1 ZZEF1 TGOLN2 SLC16A1 ICMT NUP210

9.23e-051621317int:TMEM41B
GeneFamilyCytochrome P450 family 11

CYP11B1 CYP11B2

7.33e-0539021007
GeneFamilyGuanylate cyclase receptors

NPR1 GUCY2C

5.06e-047902343
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

EPHB2 SIGMAR1 CD109 SREBF2 NOL11 RTN3 SLC46A1 SLC35E2B ZZEF1 SERPINH1 ADCY6 TGOLN2 SLC16A1 ICMT MRC2 CHPF

7.23e-0770313516MM1055
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

EPHB2 SIGMAR1 CD109 SREBF2 NOL11 RTN3 SLC46A1 SLC35E2B ZZEF1 SERPINH1 ADCY6 TGOLN2 SLC16A1 ICMT MRC2

2.46e-0668113515M5314
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NECTIN3 SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 HAS1 CHPF

1.78e-0719813680dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 ABCA13 CUBN DCC AEBP1 PCDH15 DNAH5

9.05e-07169136712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 SERPINH1 IGF1 TXNDC5 AEBP1 LOXL4 CHPF

2.12e-061921367b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN2 MYO1B SUCNR1 TMEM52B TFCP2L1 ANKRD34B TRPV5

2.35e-0619513673f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 HAS1 CHPF

2.43e-061961367d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 LOXL4

2.43e-061961367fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 SLC16A12 IGF1 AEBP1 MRC2 DIO2 HAS1

2.60e-061981367bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCelldistal-2-mesenchymal-Adventitial_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 SLC16A12 IGF1 AEBP1 MRC2 DIO2 HAS1

2.69e-06199136797b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B ADGRG4 TFCP2L1 TRPV6 TRPV5

9.20e-0615813667960337d87afecf2692ab65e5991f052ceddfacc
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUCNR1 OTC NIPAL1 LOXL4 RORC SLC38A3

1.14e-05164136690afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Clu_(Clu)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CD109 CUBN GUCY2C LOXL4 BMP15

1.15e-059613659a1da3809073a4321134bf3767e0a40398b69caa
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 OTC PDE12 KCNU1 LOXL4 NOC4L

1.39e-05170136645de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

NPC1 LPCAT1 TFCP2L1 SLC16A1 NIPAL1 TRPV6

1.54e-051731366f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 CUBN DCC AEBP1 PCDH15 DNAH5

1.54e-05173136666f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 CUBN DCC AEBP1 PCDH15 DNAH5

1.54e-051731366649b08a409095592cccf31883be69c754411280d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B TFCP2L1 DIO2 TRPV6 TRPV5

1.75e-051771366c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CD109 CUBN GUCY2C RORC BMP15

1.86e-0510613657079111add27d7b3411dfe739280d62dc256a174
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CD109 CUBN GUCY2C RORC BMP15

1.86e-051061365a6334b67be05f78145b57271b7959471b80bd67f
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SPTBN2 TMEM52B TFCP2L1 AEBP1 TRPV5

1.93e-051801366fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SPTBN2 TMEM52B TFCP2L1 AEBP1 TRPV5

1.93e-0518013666763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 SERPINH1 ART4 AEBP1 HAS1 CHPF

2.12e-051831366a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCelldroplet-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 SERPINH1 ART4 AEBP1 HAS1 CHPF

2.12e-051831366ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB2 CD109 ART4 AEBP1 DIO2 HAS1

2.25e-0518513661b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 ABCA13 PRDM8 AEBP1 MRC2 LOXL4

2.39e-0518713664e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 ABCA13 PRDM8 AEBP1 MRC2 LOXL4

2.39e-051871366d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 ABCA13 PRDM8 AEBP1 MRC2 LOXL4

2.39e-051871366827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 NPR1 ABCA13 AEBP1 MRC2 LOXL4

2.39e-0518713669225caf66e06ebe57e90d677122acb6498607f36
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B SERPINH1 AEBP1 MRC2 HAS1 TNS1

2.39e-051871366976b74d081b7fba8620768613cc26f9262cd7b16
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.54e-051891366c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.54e-0518913662a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.54e-0518913665a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.61e-0519013669cd147a174017ebda23cc47b6d4552d898acd092
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 ART4 AEBP1 MRC2 CHPF TNS1

2.69e-051911366094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCellfacs-Lung-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 ART4 AEBP1 MRC2 CHPF TNS1

2.69e-051911366ba02cbdfda6a94374a6472eb88499059979af472
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 IGF1 ART4 AEBP1 MRC2 CHPF

2.69e-051911366997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPTBN2 TMEM52B TFCP2L1 ANKRD34B TRPV6 TRPV5

2.77e-051921366760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCelldroplet-Lung-nan-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B SERPINH1 ART4 AEBP1 MRC2 TNS1

2.77e-051921366df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB2 SERPINH1 IGF1 ART4 AEBP1 DIO2

2.77e-051921366ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B SERPINH1 ART4 AEBP1 MRC2 TNS1

2.77e-051921366d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCelldroplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B SERPINH1 ART4 AEBP1 MRC2 TNS1

2.77e-051921366c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 IGF1 ART4 AEBP1 MRC2 CHPF

2.77e-0519213668df15085b35b86f39debd933284cb703c5dd63c2
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.85e-051931366ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 SERPINH1 AEBP1 MRC2 LOXL4 HAS1

2.85e-051931366316ebdf15f75d88c348f909b643fcd315364ca84
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 TMEM52B TFCP2L1 NIPAL1 TRPV6 TRPV5

2.85e-0519313660208fcd8ea4662f40fc2c072ac220d97823eec12
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 AEBP1 MRC2 DIO2 HAS1 CHPF

2.85e-0519313660a665531d581d4e3941e29d3f95569da8f166447
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 TMEM52B TFCP2L1 NIPAL1 TRPV6 TRPV5

2.85e-05193136604d47ba7cc1f19f1ffb18d9e68469e75063697cf
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 SERPINH1 AEBP1 MRC2 LOXL4 HAS1

2.85e-0519313661afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 NPR1 ABCA13 AEBP1 MRC2 SLC2A13

2.85e-0519313660f2167eef8203a5659c8c72e4e77646003d64797
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 CHPF

2.85e-051931366428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN2 RTN3 MYO1B TGOLN2 TFCP2L1 CELSR2

2.85e-051931366e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 CHPF

2.85e-051931366eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 SERPINH1 AEBP1 MRC2 LOXL4 HAS1

2.85e-0519313668dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 AEBP1 MRC2 DIO2 HAS1 CHPF

2.85e-05193136624ce1f37cca655415410d2403a52d1ebb3332280
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPINH1 IGF1 ART4 AEBP1 MRC2 TNS1

2.85e-05193136630481fb01c7acf85beae10213f038da86bed6777
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ISLR2 NPR1 NECTIN3 SERPINH1 AEBP1 HAS1

2.94e-0519413667b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1 AEBP1 MRC2 DIO2 HAS1 CHPF

2.94e-0519413662d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCellMesenchymal_cells-Endosteal_fibro.|World / Lineage and Cell class

ISLR2 NPR1 SERPINH1 PRDM8 AEBP1 HAS1

3.02e-051951366d53974d1866e23c894ffd492ea11d20422919b11
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN2 MYO1B TMEM52B TFCP2L1 ANKRD34B TRPV5

3.02e-051951366e94bac6a5c788ee160d7feaf2a3c512a3691f995
ToppCellMesenchymal_cells-Arteriolar_fibro.|Mesenchymal_cells / Lineage and Cell class

SIGMAR1 SERPINH1 IGF1 AEBP1 DIO2 CHPF

3.20e-051971366cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 CHPF

3.29e-0519813661b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellfacs-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINH1 TXNDC5 AEBP1 MRC2 HAS1 CHPF

3.29e-051981366e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 CHPF

3.29e-051981366524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINH1 IGF1 TXNDC5 AEBP1 MRC2 CHPF

3.39e-051991366edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B TFCP2L1 ANKRD34B TRPV6 TRPV5

3.39e-0519913663cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

BRINP3 IGF1 AEBP1 MRC2 DIO2 CHPF

3.48e-0520013669996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-052001366f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-052001366cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-052001366c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellmedial-mesenchymal-Adventitial_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 IGF1 AEBP1 MRC2 DIO2 HAS1

3.48e-05200136687a5a0c252c08ba10316c21f6a9d5244c4d98c74
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-0520013664fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-052001366310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellmedial-2-mesenchymal-Adventitial_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 IGF1 AEBP1 MRC2 DIO2 HAS1

3.48e-0520013666ccf44f10d2cee5f48b8f05bd9a1b94057184d56
ToppCellmedial-mesenchymal-Adventitial_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRINP3 IGF1 AEBP1 MRC2 DIO2 HAS1

3.48e-0520013665ee1318a74ca28a81bd81c20c611de84c17636b0
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

CHL1 BRINP3 GRIK3 DCC PCDH15 SLC2A13

3.48e-052001366961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CD109 TFCP2L1 GUCY2C LOXL4 BMP15

3.96e-051241365b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CD109 TFCP2L1 GUCY2C LOXL4 BMP15

3.96e-051241365231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

GPATCH1 CERS6 STK33 LOXL4 GP1BA

4.78e-0512913655e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CELF6 NECTIN3 IGF1 AEBP1 TNS1

4.96e-05130136556b9c3325e011f1dbaf9efc71bd6e1af4f96fda6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 CELF6 ABCA13 TMPRSS12 CNTD1

5.33e-05132136597e7d5f7086c6213aec4eaa581bc182338189029
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AEBP1 DIO2 LOXL4 SLC2A13 SLC38A3

5.93e-0513513655b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

SPTBN2 ACOX2 STK33 DIO2 DNAH5

8.32e-051451365ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A3 B4GAT1 TXNDC5 ICMT RORC

8.87e-051471365f703cb0330304799d16e457215269c7732c9d5d5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 IGF1 AEBP1 PCDH15 SLC2A13

9.46e-05149136510ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACTR5 DHX57 PRPF8 CDC7 UTP15

9.46e-05149136565778f19599b4955c0a16f0121237656449431fb
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

EPHB2 IGF1 ART4 NIPAL1 DIO2

1.44e-041631365961c3a1303108afd680365466045f3460a30a7b0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B STK33 TRPV6 TRPV5

1.48e-0416413656fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPATCH1 DHX57 GRIK3 WDHD1 DNAH5

1.53e-0416513651703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 COQ8B SUCNR1 TM6SF2 TRPV6

1.57e-041661365c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 COQ8B SUCNR1 TM6SF2 TRPV6

1.57e-0416613650975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPC1 HEATR1 DOCK5 MRC2 PNPLA7

1.61e-0416713655c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 CERS6 TFCP2L1 TRPV6 SLC38A3

1.66e-0416813653e3f611e9bbec8224264666be14a4e7db343070e
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPCAT1 RIF1 THADA SLC16A1 NOC4L

1.66e-04168136508f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellCOVID-19_Mild-Neu_2|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

B4GAT1 TMPRSS12 HIC2 HEATR1 CARNMT1

1.85e-041721365f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN2 SLC46A1 CNTD1 CELSR2 ABCD1

1.85e-0417213651bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 CHL1 GRIK3 THADA RORC

2.11e-041771365291231b1520c135e92739e201495fe1935efa927
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA13 ANKRD34B CASTOR1 AEBP1 PNPLA7

2.11e-04177136530f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B TFCP2L1 TRPV6 TRPV5

2.23e-041791365666072c0e8448dbaec1683d18368ec2502453f90
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPHB2 SERPINH1 IGF1 AEBP1 HAS1

2.29e-0418013659adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ISLR2 SERPINH1 AEBP1 MRC2 DIO2

2.34e-041811365bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1B TMEM52B TFCP2L1 DIO2 TRPV5

2.34e-041811365e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
Drug3 -hydroxypregn-5-en-20-one

NPC1 SIGMAR1 CYP11B1 CYP11B2 ADCY6 TFCP2L1 IGF1 LIPE GUCY2C HAS1

1.73e-0623813610CID000001027
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; PC3; HT_HG-U133A

LPCAT1 B4GAT1 ACOX2 TGOLN2 CDC7 THADA WDHD1 NOC4L CLEC16A

2.59e-0619413691822_DN
DiseaseGlucocorticoid-remediable aldosteronism

CYP11B1 CYP11B2

1.96e-0521312C1260386
Diseaseadrenal cortical adenoma (is_marker_for)

CYP11B1 CYP11B2

1.96e-0521312DOID:0050891 (is_marker_for)
Diseasecongenital adrenal hyperplasia (implicated_via_orthology)

CYP11B1 CYP11B2

5.85e-0531312DOID:0050811 (implicated_via_orthology)
DiseaseColorectal Carcinoma

CHL1 ABCA13 SPTBN2 CD109 MYO1B GRIK3 CUBN DCC ERGIC3 GUCY2C KDM6A PIK3R5

7.21e-0570213112C0009402
Diseasemyocardial infarction

NBEAL1 CD109 SERPINH1 PRDM8 THADA CELSR2 CASTOR1 TNS1

1.77e-043501318EFO_0000612
Diseaseprimary hyperaldosteronism (is_implicated_in)

CYP11B1 CYP11B2

1.94e-0451312DOID:446 (is_implicated_in)
Diseaseuterine fibroid

CD109 RTN3 DOCK5 IGF1 NIPAL1 TNS1

2.71e-041991316EFO_0000731
DiseaseConn Syndrome

CYP11B1 CYP11B2

2.90e-0461312C1384514
DiseaseNeonatal Alloimmune Thrombocytopenia

CD109 GP1BA

2.90e-0461312C3853779
DiseaseFNAITP

CD109 GP1BA

2.90e-0461312C3854603
DiseaseHyperaldosteronism

CYP11B1 CYP11B2

2.90e-0461312C0020428
Diseaseprotocadherin alpha-7 measurement

CYP11B1 CYP11B2

4.05e-0471312EFO_0801973
Diseaseprotein FAM163B measurement

CYP11B1 CYP11B2

6.90e-0491312EFO_0802936
Diseaseandrostenedione measurement

CYP11B1 CYP11B2

8.60e-04101312EFO_0007972
Diseasehereditary spastic paraplegia (implicated_via_orthology)

RTN3 NIPAL1 PNPLA7

9.27e-04431313DOID:2476 (implicated_via_orthology)
Diseasemyocardial infarction (is_implicated_in)

NPR1 BRINP3 IGF1 GP1BA

1.01e-03991314DOID:5844 (is_implicated_in)
Diseasecell growth regulator with EF hand domain protein 1 measurement

CYP11B1 CYP11B2

1.05e-03111312EFO_0801461
Disease3-hydroxyanthranilate 3,4-dioxygenase measurement

CYP11B1 CYP11B2

1.05e-03111312EFO_0021862
Diseasebreast cancer (biomarker_via_orthology)

IGF1 KDM1A

1.48e-03131312DOID:1612 (biomarker_via_orthology)
DiseaseThyroid Diseases

TGOLN2 DIO2

1.48e-03131312C0040128
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

DCC ZZEF1

1.72e-03141312EFO_0006830, EFO_0006896
DiseaseSitus ambiguus

BCL9L DNAH5

1.98e-03151312C0266642
Diseasefocal segmental glomerulosclerosis

GPATCH1 PPCS

2.25e-03161312EFO_0004236
Diseaseneutrophil collagenase measurement

ABCA13 CYP11B1

2.25e-03161312EFO_0008248
Diseasetriacylglycerol 50:5 measurement

MYO1B TM6SF2

2.25e-03161312EFO_0010412
DiseaseIGF-1 measurement, IGFBP-3 measurement

IGF1 CELSR2

2.55e-03171312EFO_0004626, EFO_0004627
Diseasecoronary artery disease

NPC1 NBEAL1 CD109 SERPINH1 DOCK5 PRDM8 THADA IGF1 CELSR2 CASTOR1 NUP210 TNS1 OR56B4

2.57e-03119413113EFO_0001645
Diseasehypertension (implicated_via_orthology)

NPR1 CYP11B1 CYP11B2 IGF1

2.59e-031281314DOID:10763 (implicated_via_orthology)
Diseaseanti-Mullerian hormone measurement

TTC28 OR56B4

3.53e-03201312EFO_0004769
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

DCC TM6SF2

3.89e-03211312OBA_2045104
Diseaseneurodegenerative disease (implicated_via_orthology)

GRIK3 PPCS PNPLA7 CLEC16A

4.05e-031451314DOID:1289 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
IVANYFSELFHLLSS

BHLHB9

441

Q6PI77
LAISYAFHFLAVSLL

ACOX2

351

Q99424
AVSLLEFFQHSYTAI

ACOX2

361

Q99424
SVTLETLHQLAASYF

BRINP3

171

Q76B58
SVNYHLLFTLVLFSL

ACER3

116

Q9NUN7
YHFENLANELSIELS

CARNMT1

346

Q8N4J0
EAQLATVLAYALSSH

B4GAT1

131

O43505
TAAVALHYFLLVSFT

ADGRG4

2811

Q8IZF6
AIATTLIDVLFYSHS

CASTOR1

196

Q8WTX7
AISFASAHLTLTEPY

AEBP1

816

Q8IUX7
ALALYLHAQQVESTA

ADCY6

906

O43306
YELEATTALNFLHLY

CCNG2

151

Q16589
ASRITLHGFIYLQAS

DGUOK

181

Q16854
DVYSFTLLHGITISN

ABCA13

1771

Q86UQ4
LLLDYSFQHLGVSSQ

ACTR5

111

Q9H9F9
LSVNSDTLLFHYLFA

CELSR2

2581

Q9HCU4
ASFHDGLLLYIQAVT

NPR1

351

P16066
AYVFTLLVSLYLHDN

MT-ATP6

211

P00846
YTTAILQHQAALLAA

CELF6

246

Q96J87
TFDALSALSHLQLYH

ISLR2

166

Q6UXK2
LSLESALQYFNLSHS

NBEAL1

561

Q6ZS30
ISYALILSSIFHIDS

OR8B8

216

Q15620
LNALEASVSYFSHEL

GUCY2C

206

P25092
LYHLDIYFSSQLQSA

INTS15

21

Q96N11
ALLNAILHSAYSETF

NOL11

586

Q9H8H0
VVAFAASVAHLYSNL

ABCD1

201

P33897
LSLQDHSSYSALVYA

ANKRD34B

111

A5PLL1
LFADQAEILLSNHYT

NUP210

1691

Q8TEM1
QHYSSEKSAFLLSIL

SLC16A1

291

P53985
LESSSHYVISLKAFN

DCC

786

P43146
FLSHLAIVDISYASN

OR2A14

61

Q96R47
HFGAQDILTLYELST

SLC46A1

281

Q96NT5
EAAILTLAPHSSYFD

LPCAT1

126

Q8NF37
VLASFTYLSFSALAH

PAQR7

111

Q86WK9
TYLSFSALAHLLQAK

PAQR7

116

Q86WK9
SSVADFLLVYIDEAH

DIO2

151

Q92813
SIEVFTHYDLLTLNG

LOXL4

616

Q96JB6
SLDAFSEFHLTVLAY

CHL1

881

O00533
LDVSSIVLSAQDFYH

ATAD2B

641

Q9ULI0
TDYESSLKHFQLALV

KDM6A

181

O15550
SLDIAFLLLYFNDTH

BMP15

226

O95972
AYHSFSTGLSQQVLL

DCAF4L2

196

Q8NA75
QHLIIFDYISVSASL

ENOSF1

366

Q7L5Y1
SDLLAHTQYTFEIQA

EPHB2

396

P29323
FARAALLYASSHSTL

GPATCH1

551

Q9BRR8
QILADYLTLQEHYSS

OTC

171

P00480
FSLLSQHDISFYEAL

PDE12

391

Q6L8Q7
FTVAGLIDSLIYHSA

ERGIC3

356

Q9Y282
QLSAHALAALQEFYA

EEF1AKMT1

11

Q8WVE0
HLDFLLAYTISAIHQ

HEATR6

116

Q6AI08
LLSLASYEEEHFVAN

MRC2

711

Q9UBG0
LDSLLATAFYNYHVL

KCNU1

906

A8MYU2
TGNLFIIILSYVDSH

OR2J2

41

O76002
VTFLALHNYLGLTTE

PNPLA7

276

Q6ZV29
NESELTGLHSLVALY

LRRC70

76

Q7Z2Q7
LFHGSLAFTYLNSVL

OXER1

336

Q8TDS5
FLSHLAIIDISYASN

OR2A5

61

Q96R48
YHTVLQTSADFIDAL

NPC1

1041

O15118
FSSYAVILHSVLRLN

OR56B4

221

Q8NH76
AVEFTTLADYLHLLQ

PPCS

146

Q9HAB8
LHLFLNDYTSVFTVT

PCDH15

441

Q96QU1
ELLSSDNALYFHLYS

CUBN

556

O60494
DIEVAAYALLSHFLQ

CD109

1141

Q6YHK3
LDSFLLNHSLEYTVA

ICMT

121

O60725
LEATSYLSHQLDFNV

KDM1A

386

O60341
NYTEAAYTLLLHAEL

DOCK5

1256

Q9H7D0
LLATTLKQAHALFYT

COG1

261

Q8WTW3
VSAQEALVHDYFSAL

CDK15

376

Q96Q40
QVDLSVHAYASFIDA

DTX3L

426

Q8TDB6
YLEHESFLDILNSLS

CDC7

136

O00311
FLHLELLSSYDVDVN

EPM2AIP1

281

Q7L775
SHLNAIEDASFLYEL

DHX57

341

Q6P158
YVFTTHLANTAAEAV

BCL9L

241

Q86UU0
SIFHYTIEASNLALF

CYP11B1

191

P15538
HHLVSIFLITFSYVN

CERS6

211

Q6ZMG9
ANFLYDASSHQVTLL

COQ8B

371

Q96D53
AFLSAHLVAQSLFAY

HAS1

61

Q92839
ILHLSENLLYTFSLA

GP1BA

51

P07359
AHYGLSDVFDNLIIS

GBF1

966

Q92538
HLFYLALCLLTFTSS

IGF1

31

P05019
TSHQSQLTAFFLEAL

HEATR1

1861

Q9H583
SIFHYTIEASNLALF

CYP11B2

191

P19099
YASLSHAILDLVQYL

GRIK3

156

Q13003
VHFQLSIGNLSSVYS

CEP295

2226

Q9C0D2
AVDLFLLSSQYSDLA

SEC24B

861

O95487
ADLFLSSSHLPAYLV

NOC4L

351

Q9BVI4
ALASIAEFSYAILTH

CNTD1

286

Q8N815
VLISAILSSYFLNEH

NIPAL1

151

Q6NVV3
LGYHLDVSLAFSEIS

C9

381

P02748
ALVAVSEHFLTSYDI

DNAH5

3121

Q8TE73
SHNLAELEAYLAALT

LIPE

406

Q05469
FGHLYTILTTQLTND

MTX2

216

O75431
QEEFSIHLSQALSYL

MROH5

1231

Q6ZUA9
NVLVSLTFLHTAEYL

SLC2A13

556

Q96QE2
VFAALHLTALFLTVY

GRIN3B

581

O60391
ASSIYFKSLVLHDNL

HIC2

66

Q96JB3
LDVDITLSSEAFHNY

RTN3

916

O95197
KVVHSFDYAASILSL

UTP15

281

Q8TED0
FDYAASILSLALAHE

UTP15

286

Q8TED0
TLLQVFHLLQAYSDS

THADA

1406

Q6YHU6
FLLTAVALLSSYSIH

SLC38A3

101

Q99624
SLASAIAYLHNNDIV

STK33

221

Q9BYT3
QYSAAIAFTLALFSH

SMG5

376

Q9UPR3
SLSSALGVVYFLHAV

SLC16A12

406

Q6ZSM3
ALEHNFSAIYGALTL

RIF1

671

Q5UIP0
NHSTVYEFILLGLTD

OR5AL1

21

P0C617
LSHTSLYDSIAFIAL

PRDM8

46

Q9NQV8
LHASLSEYVLLFGTA

SIGMAR1

96

Q99720
LYLASVFHATAFELD

SERPINH1

346

P50454
AAYLIALLLDTAAHF

SWSAP1

111

Q6NVH7
LHSLILDFSAVSFLD

SLC26A3

646

P40879
SNLSVYHAIFLEELT

TFCP2L1

396

Q9NZI6
ISYSDTHTNQLLLFY

OR5T2

226

Q8NGG2
DVYELFLHFSSLHVL

CHPF

706

Q8IZ52
LNILFENISHETSLY

CLEC16A

101

Q2KHT3
VLIAIDLAYNLHSAY

PRPF8

1701

Q6P2Q9
ESSHFFAYLVTAAIL

TGOLN2

381

O43493
SLSALHFSEDEIALY

RORC

406

P51449
ALADYAQTIHQLAAS

SPTBN2

1636

O15020
SAYTTLLLHAFQATF

PIK3R5

191

Q8WYR1
FITSSHNTYLVGDQL

PLCH2

336

O75038
YTHSSLFLALYLAND

SPDYC

106

Q5MJ68
NYTIADLSHEAILLA

WDHD1

486

O75717
SALEYLKLLHSFVDS

SREBF2

836

Q12772
IYLTNTFSFAILIHD

TMEM131

456

Q92545
NFGSLSALVYQHSII

TNS1

1546

Q9HBL0
HVVAASALLYFILLS

TMEM52B

6

Q4KMG9
TALHIAALYDNLEAA

TRPV6

121

Q9H1D0
LSVALLFVGSSHLYS

TMPRSS12

6

Q86WS5
LTDGVLFHLQSVTAY

SLC35E2B

301

P0CK96
VLHANLYTSILFLTF

SUCNR1

101

Q9BXA5
LVENYISFYDHLASL

ZNFX1

1701

Q9P2E3
TVHFALQSLLSLFDS

TTC28

1926

Q96AY4
LLFAALALYSAHLAS

ZZEF1

1901

O43149
LYELSASNFELHVAQ

TXNDC5

191

Q8NBS9
SALPVSYALNHVSAL

TM6SF2

16

Q9BZW4
LLFVAVYSLSHGEVS

TM6SF2

46

Q9BZW4
AFHVSYLDIEELSLS

TARBP2

306

Q15633
SLSAVNDFYSHIVLA

WDR27

661

A2RRH5
TALHIAALYDNLEAA

TRPV5

81

Q9NQA5
HVFYQLLSGASEELL

MYO1B

206

O43795
VAILFYTLNSNVHSD

ART4

121

Q93070
YSLNDATITLHNIGF

NECTIN3

126

Q9NQS3