Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH7 DNAH1 DNAH8	1.06e-04	18	104	3	GO:0008569
GeneOntologyMolecularFunction	6-phosphofructo-2-kinase activity	PFKFB2 PFKFB3	1.60e-04	4	104	2	GO:0003873
GeneOntologyMolecularFunction	fructose-2,6-bisphosphate 2-phosphatase activity	PFKFB2 PFKFB3	2.66e-04	5	104	2	GO:0004331
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH7 DNAH1 DNAH8	4.09e-04	28	104	3	GO:0051959
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB2 PFKFB3	5.55e-04	7	104	2	GO:0008443
GeneOntologyCellularComponent	secretory granule membrane	LILRA3 DNAJC13 MANBA DSP STXBP5 SIGLEC14 SIGLEC5 ITPR2 USP8	4.24e-05	329	105	9	GO:0030667
GeneOntologyCellularComponent	ficolin-1-rich granule membrane	LILRA3 DSP SIGLEC14 SIGLEC5	2.52e-04	61	105	4	GO:0101003
GeneOntologyCellularComponent	axonemal dynein complex	DNAH7 DNAH1 DNAH8	2.61e-04	25	105	3	GO:0005858
Domain	ig	LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	8.92e-06	190	101	8	PF00047
Domain	Immunoglobulin	LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	8.92e-06	190	101	8	IPR013151
Domain	Dynein_heavy_chain_D4_dom	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	IPR024317
Domain	Dynein_HC_stalk	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	IPR013602
Domain	DHC_N2	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	PF08393
Domain	MT	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	PF12777
Domain	AAA_8	DNAH7 DNAH1 DNAH8	5.35e-05	14	101	3	PF12780
Domain	DHC_fam	DNAH7 DNAH1 DNAH8	6.66e-05	15	101	3	IPR026983
Domain	Dynein_heavy	DNAH7 DNAH1 DNAH8	6.66e-05	15	101	3	PF03028
Domain	Dynein_heavy_dom	DNAH7 DNAH1 DNAH8	6.66e-05	15	101	3	IPR004273
Domain	6Phosfructo_kin	PFKFB2 PFKFB3	1.73e-04	4	101	2	IPR013079
Domain	6Pfruct_kin	PFKFB2 PFKFB3	1.73e-04	4	101	2	IPR003094
Domain	6PF2K	PFKFB2 PFKFB3	1.73e-04	4	101	2	PF01591
Domain	TUDOR	TDRD9 KDM4C TDRD6	2.51e-04	23	101	3	PS50304
Domain	DUF4704	NBEAL1 NBEA	2.86e-04	5	101	2	IPR031570
Domain	DUF4704	NBEAL1 NBEA	2.86e-04	5	101	2	PF15787
Domain	IGc2	LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5	2.88e-04	235	101	7	SM00408
Domain	Ig_sub2	LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5	2.88e-04	235	101	7	IPR003598
Domain	TUDOR	TDRD9 KDM4C TDRD6	4.09e-04	27	101	3	SM00333
Domain	RIH_assoc-dom	RYR2 ITPR2	4.28e-04	6	101	2	IPR013662
Domain	-	DSP DST	4.28e-04	6	101	2	3.90.1290.10
Domain	PH_BEACH	NBEAL1 NBEA	4.28e-04	6	101	2	PF14844
Domain	A1B_glyco/leuk_Ig-like_rcpt	LILRA3 LILRA2	4.28e-04	6	101	2	IPR016332
Domain	Ins145_P3_rec	RYR2 ITPR2	4.28e-04	6	101	2	PF08709
Domain	RIH_assoc	RYR2 ITPR2	4.28e-04	6	101	2	PF08454
Domain	RIH_dom	RYR2 ITPR2	4.28e-04	6	101	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR2	4.28e-04	6	101	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR2	4.28e-04	6	101	2	IPR015925
Domain	-	RYR2 ITPR2	4.28e-04	6	101	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR2	4.28e-04	6	101	2	PF01365
Domain	IG	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	4.62e-04	421	101	9	SM00409
Domain	Ig_sub	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	4.62e-04	421	101	9	IPR003599
Domain	Peptidase_Metallo	ASTL MMP11 MMP17	5.06e-04	29	101	3	IPR006026
Domain	ZnMc	ASTL MMP11 MMP17	5.06e-04	29	101	3	SM00235
Domain	Tudor	TDRD9 KDM4C TDRD6	5.60e-04	30	101	3	IPR002999
Domain	Plectin	DSP DST	5.97e-04	7	101	2	PF00681
Domain	Plectin_repeat	DSP DST	5.97e-04	7	101	2	IPR001101
Domain	PLEC	DSP DST	5.97e-04	7	101	2	SM00250
Domain	PH-BEACH_dom	NBEAL1 NBEA	7.94e-04	8	101	2	IPR023362
Domain	-	NBEAL1 NBEA	7.94e-04	8	101	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEA	7.94e-04	8	101	2	PS51783
Domain	-	ASTL ADAMTS16 MMP11 MMP17	9.74e-04	81	101	4	3.40.390.10
Domain	MetalloPept_cat_dom	ASTL ADAMTS16 MMP11 MMP17	9.74e-04	81	101	4	IPR024079
Domain	IRF	IRF1 IRF4	1.02e-03	9	101	2	SM00348
Domain	IRF	IRF1 IRF4	1.02e-03	9	101	2	PF00605
Domain	BEACH	NBEAL1 NBEA	1.02e-03	9	101	2	PS50197
Domain	Beach	NBEAL1 NBEA	1.02e-03	9	101	2	PF02138
Domain	-	NBEAL1 NBEA	1.02e-03	9	101	2	1.10.1540.10
Domain	Interferon_reg_fac_CS	IRF1 IRF4	1.02e-03	9	101	2	IPR019817
Domain	Beach	NBEAL1 NBEA	1.02e-03	9	101	2	SM01026
Domain	PG/BPGM_mutase_AS	PFKFB2 PFKFB3	1.02e-03	9	101	2	IPR001345
Domain	Interferon_reg_fact_DNA-bd_dom	IRF1 IRF4	1.02e-03	9	101	2	IPR001346
Domain	BEACH_dom	NBEAL1 NBEA	1.02e-03	9	101	2	IPR000409
Domain	IRF_1	IRF1 IRF4	1.02e-03	9	101	2	PS00601
Domain	IRF_2	IRF1 IRF4	1.02e-03	9	101	2	PS51507
Domain	ConA-like_dom	CNTNAP3B NBEAL1 CNTNAP3 NBEA RYR2 HERC1	1.22e-03	219	101	6	IPR013320
Domain	MIR	RYR2 ITPR2	1.27e-03	10	101	2	PF02815
Domain	MIR_motif	RYR2 ITPR2	1.27e-03	10	101	2	IPR016093
Domain	MIR	RYR2 ITPR2	1.27e-03	10	101	2	PS50919
Domain	MIR	RYR2 ITPR2	1.27e-03	10	101	2	SM00472
Domain	Cyt_P450_E_grp-IV	CYP26A1 CYP26C1	1.27e-03	10	101	2	IPR002403
Domain	PGAM	PFKFB2 PFKFB3	1.27e-03	10	101	2	SM00855
Domain	PG_MUTASE	PFKFB2 PFKFB3	1.27e-03	10	101	2	PS00175
Domain	IG_LIKE	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	1.37e-03	491	101	9	PS50835
Domain	CYSTEINE_SWITCH	ADAMTS16 MMP11 MMP17	1.41e-03	41	101	3	PS00546
Domain	Ig-like_fold	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 PKHD1L1 SEMA3B ADGRF3	1.51e-03	706	101	11	IPR013783
Domain	Ig-like_dom	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 SEMA3B	1.62e-03	503	101	9	IPR007110
Domain	Pept_M10_metallopeptidase	ADAMTS16 MMP11 MMP17	1.62e-03	43	101	3	IPR001818
Domain	Galactose-bd-like	CNTNAP3B MANBA HECTD3 CNTNAP3	1.69e-03	94	101	4	IPR008979
Domain	His_Pase_superF_clade-1	PFKFB2 PFKFB3	1.84e-03	12	101	2	IPR013078
Domain	His_Phos_1	PFKFB2 PFKFB3	1.84e-03	12	101	2	PF00300
Domain	DUF4599	SPATA31D4 SPATA31D3	1.84e-03	12	101	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	1.84e-03	12	101	2	IPR027970
Domain	ZINC_PROTEASE	ASTL ADAMTS16 MMP11 MMP17	1.97e-03	98	101	4	PS00142
Domain	SH3_1	ARHGEF19 MYO1E ITSN1 DST PACSIN2	1.97e-03	164	101	5	PF00018
Domain	ARM-type_fold	SMG1 DNAJC13 NBEAL1 NBEA APOB MAP3K1 ITPR2	2.44e-03	339	101	7	IPR016024
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH8	2.53e-03	14	101	2	IPR011704
Domain	TUDOR	TDRD9 TDRD6	2.53e-03	14	101	2	PF00567
Domain	AAA_5	DNAH1 DNAH8	2.53e-03	14	101	2	PF07728
Domain	Beta/gamma_crystallin	CRYBG2 CRYBA2	2.90e-03	15	101	2	IPR001064
Domain	CRYSTALLIN_BETA_GAMMA	CRYBG2 CRYBA2	2.90e-03	15	101	2	PS50915
Domain	Crystall	CRYBG2 CRYBA2	2.90e-03	15	101	2	PF00030
Domain	XTALbg	CRYBG2 CRYBA2	2.90e-03	15	101	2	SM00247
Domain	-	ISLR2 LILRA3 LILRA2 SDK2 MYOM1 SIGLEC14 FGFRL1 SIGLEC5 PKHD1L1 SEMA3B	3.13e-03	663	101	10	2.60.40.10
Domain	G_crystallin-rel	CRYBG2 CRYBA2	4.19e-03	18	101	2	IPR011024
Domain	Pept_M10A_stromelysin-type	MMP11 MMP17	4.19e-03	18	101	2	IPR016293
Domain	-	PFKFB2 PFKFB3	5.16e-03	20	101	2	3.40.50.1240
Domain	His_PPase_superfam	PFKFB2 PFKFB3	5.16e-03	20	101	2	IPR029033
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	DSP ITGA6 DST	2.22e-06	9	105	3	12482924
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	DSP ITGA6 DST	4.33e-06	11	105	3	12802069
Pubmed	Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.	SIGLEC14 SIGLEC5	9.03e-06	2	105	2	24799499
Pubmed	Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain.	PFKFB2 PFKFB3	9.03e-06	2	105	2	11245921
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	9.03e-06	2	105	2	31150793
Pubmed	Polymorphisms of FDPS, LRP5, SOST and VKORC1 genes and their relation with osteoporosis in postmenopausal Romanian women.	FDPS LRP5	9.03e-06	2	105	2	31774873
Pubmed	Human osteosarcoma CD49f(-)CD133(+) cells: impaired in osteogenic fate while gain of tumorigenicity.	ITGA6 PROM1	9.03e-06	2	105	2	23045288
Pubmed	Expression of Pfkfb isoenzymes during in vitro differentiation of mouse embryonic stem cells into insulin-producing cells.	PFKFB2 PFKFB3	9.03e-06	2	105	2	38813509
Pubmed	Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.	RYR2 ITPR2	9.03e-06	2	105	2	28158491
Pubmed	Overexpression of ubiquitous 6-phosphofructo-2-kinase in the liver of transgenic mice results in weight gain.	PFKFB2 PFKFB3	9.03e-06	2	105	2	17991424
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	9.03e-06	2	105	2	26807827
Pubmed	Mitochondrial calcium overload is a key determinant in heart failure.	RYR2 ITPR2	9.03e-06	2	105	2	26217001
Pubmed	The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia.	ITGA6 MECOM	9.03e-06	2	105	2	22295105
Pubmed	Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.	SIGLEC14 SIGLEC5	9.03e-06	2	105	2	26459514
Pubmed	Genetic predictors of skeletal outcomes in healthy fertile women: the Bonturno study.	FDPS LRP5	9.03e-06	2	105	2	23238007
Pubmed	Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids.	DSP ITGA6	9.03e-06	2	105	2	33502623
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH7 DNAH1 DNAH8	9.50e-06	14	105	3	9373155
Pubmed	Calcium handling precedes cardiac differentiation to initiate the first heartbeat.	MYOM1 RYR2 ITPR2	1.76e-05	17	105	3	27725084
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DNAJC13 STXBP5 PPFIBP1 ITGA6 NBEA ITPR2 DST SCFD1 SCIN	2.30e-05	504	105	9	34432599
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DNAJC13 PPFIBP1 PCDHB2 NBEA APOB PKHD1L1 DNAH7 RYR2 DST ADAMTS16 SCFD1	2.39e-05	777	105	11	35844135
Pubmed	Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo.	PFKFB2 PFKFB3	2.70e-05	3	105	2	14623077
Pubmed	Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	24698729
Pubmed	Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia.	PFKFB2 PFKFB3	2.70e-05	3	105	2	30819197
Pubmed	Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	11579105
Pubmed	Interferon regulatory factors: the next generation.	IRF1 IRF4	2.70e-05	3	105	2	10524230
Pubmed	Transcriptional regulation of the 230-kDa bullous pemphigoid antigen gene expression by interferon regulatory factor 1 and interferon regulatory factor 2 in normal human epidermal keratinocytes.	IRF1 DST	2.70e-05	3	105	2	15560761
Pubmed	Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes.	CYP26A1 CYP26C1	2.70e-05	3	105	2	21850183
Pubmed	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	17012248
Pubmed	Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	31520477
Pubmed	Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	23710953
Pubmed	Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	19783675
Pubmed	Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	30577572
Pubmed	A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	32247614
Pubmed	Fluconazole alters CYP26 gene expression in mouse embryos.	CYP26A1 CYP26C1	2.70e-05	3	105	2	19429397
Pubmed	Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development.	CYP26A1 CYP26C1	2.70e-05	3	105	2	18927157
Pubmed	Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida.	CYP26A1 CYP26C1	2.70e-05	3	105	2	16933217
Pubmed	A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid.	CYP26A1 CYP26C1	2.70e-05	3	105	2	14532297
Pubmed	Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development.	CYP26A1 CYP26C1	2.70e-05	3	105	2	12915310
Pubmed	Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	32134149
Pubmed	Integration of global spectral karyotyping, CGH arrays, and expression arrays reveals important genes in the pathogenesis of glioblastoma multiforme.	PROM1 CACNA2D3	2.70e-05	3	105	2	22395973
Pubmed	Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases.	CYP26A1 CYP26C1	2.70e-05	3	105	2	31419517
Pubmed	Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	25497369
Pubmed	Siglec-F is a novel intestinal M cell marker.	SIGLEC14 SIGLEC5	2.70e-05	3	105	2	27524237
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CRYBG2 ARHGEF19 MYO1E FGFRL1 EDC4 MED13L ITPR2 ORC1 DST MARK4 LRP5 HERC1 MMP17	2.93e-05	1105	105	13	35748872
Pubmed	Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation.	CYP26A1 APOB CYP26C1	4.53e-05	23	105	3	15766748
Pubmed	Discovery and refinement of loci associated with lipid levels.	DNAJC13 CYP26A1 APOB MAP3K1 CSNK1G3 FER1L4	4.53e-05	211	105	6	24097068
Pubmed	Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	17562860
Pubmed	Expression of human placental-type 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase in various cells and cell lines.	PFKFB2 PFKFB3	5.40e-05	4	105	2	9464277
Pubmed	Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	17272508
Pubmed	6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme.	PFKFB2 PFKFB3	5.40e-05	4	105	2	7574501
Pubmed	Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick.	CYP26A1 CYP26C1	5.40e-05	4	105	2	17047027
Pubmed	Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	33289969
Pubmed	IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	33976385
Pubmed	Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.	IRF1 IRF4	5.40e-05	4	105	2	28497800
Pubmed	Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.	IRF1 IRF4	5.40e-05	4	105	2	23975864
Pubmed	Plasticity in the organization and sequences of human KIR/ILT gene families.	LILRA3 LILRA2	5.40e-05	4	105	2	10781084
Pubmed	Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	19178537
Pubmed	Induction of Siglec-FhiCD101hi eosinophils in the lungs following murine hookworm Nippostrongylus brasiliensis infection.	SIGLEC14 SIGLEC5	5.40e-05	4	105	2	37251384
Pubmed	Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.	PFKFB2 PFKFB3	5.40e-05	4	105	2	10095107
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR2 ITPR2	5.40e-05	4	105	2	19120137
Pubmed	Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages.	RBP3 IRF1	5.40e-05	4	105	2	7822029
Pubmed	Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase.	PFKFB2 PFKFB3	5.40e-05	4	105	2	2837207
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	EPRS1 DNAJC13 DSP PFKFB2 PFKFB3 SEMA3B	6.16e-05	223	105	6	33731348
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	LILRA3 CYP26A1 APOB MAP3K1 FER1L4	8.39e-05	146	105	5	20686565
Pubmed	A paradoxical teratogenic mechanism for retinoic acid.	CYP26A1 CYP26C1	8.97e-05	5	105	2	22869719
Pubmed	Genetic susceptibility for chronic lymphocytic leukemia among Chinese in Hong Kong.	IRF4 ACOXL	8.97e-05	5	105	2	20731705
Pubmed	Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.	SIGLEC14 SIGLEC5	8.97e-05	5	105	2	20395633
Pubmed	Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.	SIGLEC14 SIGLEC5	8.97e-05	5	105	2	21040544
Pubmed	Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.	DNAH7 DNAH1	8.97e-05	5	105	2	39056782
Pubmed	A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.	PFKFB2 PFKFB3	8.97e-05	5	105	2	18039179
Pubmed	Siglec-F-expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis.	SIGLEC14 SIGLEC5	8.97e-05	5	105	2	35482420
Pubmed	Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens.	IRF1 IRF4	8.97e-05	5	105	2	10364426
Pubmed	Structure and function of hemidesmosomes: more than simple adhesion complexes.	ITGA6 DST	8.97e-05	5	105	2	10201522
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPRS1 DNAJC13 MYO1E DSP ITSN1 RBP3 NBEA NDUFA2 EDC4 ITPR2 SLC8A2 DST SLC25A12 CACNA2D3	1.04e-04	1431	105	14	37142655
Pubmed	Establishment of cardiac cytoarchitecture in the developing mouse heart.	MYOM1 DSP	1.34e-04	6	105	2	16337936
Pubmed	Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.	PEG10 MARK4	1.34e-04	6	105	2	23666762
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 ITPR2	1.34e-04	6	105	2	23463619
Pubmed	Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).	SIGLEC14 SIGLEC5	1.34e-04	6	105	2	14559209
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 ITPR2	1.34e-04	6	105	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 ITPR2	1.34e-04	6	105	2	25966694
Pubmed	Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.	SIGLEC14 SIGLEC5	1.34e-04	6	105	2	23880769
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	1.34e-04	6	105	2	34143959
Pubmed	Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways.	LILRA3 LILRA2	1.34e-04	6	105	2	9079806
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR2 ITPR2	1.34e-04	6	105	2	16844763
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	DNAJC13 PPFIBP1 ISOC1 APOB PFKFB2 CHIT1 DNAH1 FER1L4	1.35e-04	496	105	8	31343991
Pubmed	Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.	SIGLEC14 SIGLEC5	1.88e-04	7	105	2	23677475
Pubmed	Negative regulation of MEKK1-induced signaling by glutathione S-transferase Mu.	MAP3K1 MAPK10	1.88e-04	7	105	2	15299005
Pubmed	The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate.	PFKFB2 PFKFB3	1.88e-04	7	105	2	15896703
Pubmed	The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.	SIGLEC14 SIGLEC5	1.88e-04	7	105	2	15048729
Pubmed	Positive association between ALDH1A2 and schizophrenia in the Chinese population.	CYP26A1 CYP26C1	1.88e-04	7	105	2	19703508
Pubmed	Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain.	PROM1 FOXJ1	1.88e-04	7	105	2	25883935
Pubmed	The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.	ITGA6 DST	1.88e-04	7	105	2	10637308
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH1 DNAH8	1.88e-04	7	105	2	9256245
Pubmed	[Functions and molecular evolution of Siglecs, a family of sialic acid receptor proteins].	SIGLEC14 SIGLEC5	1.88e-04	7	105	2	18453149
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR2 ITPR2	1.88e-04	7	105	2	11860456
Pubmed	Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells.	DSP ITGA6	1.88e-04	7	105	2	18292208
Pubmed	CYP26A1 and CYP26C1 cooperate in degrading retinoic acid within the equatorial retina during later eye development.	CYP26A1 CYP26C1	1.88e-04	7	105	2	15531370
Pubmed	Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen.	SIGLEC14 SIGLEC5	1.88e-04	7	105	2	23840825
Pubmed	Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.	IRF4 ACOXL	1.88e-04	7	105	2	22700719
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	RYR2 ITPR2 SLC8A2	2.09e-04	38	105	3	30786075
Interaction	GPIHBP1 interactions	CNTNAP3B SDK2 MANBA DIPK1A CNTNAP3 VWDE LRP5	5.10e-06	133	102	7	int:GPIHBP1
Interaction	TRGV3 interactions	CNTNAP3B MANBA CNTNAP3 VWDE SEMA3B	8.56e-06	55	102	5	int:TRGV3
Interaction	BAGE2 interactions	MANBA HECTD3 CNTNAP3 VWDE LRP5	2.81e-05	70	102	5	int:BAGE2
Interaction	CEACAM8 interactions	SDK2 MANBA CNTNAP3 ITGA6 VWDE CACNA2D3	3.17e-05	119	102	6	int:CEACAM8
Interaction	CFC1 interactions	CNTNAP3B MANBA CNTNAP3 VWDE SEMA3B LRP5	4.37e-05	126	102	6	int:CFC1
Cytoband	19q13.4	LILRA3 LILRA2 SIGLEC14	8.10e-04	79	105	3	19q13.4
Cytoband	9q21.32	SPATA31D4 SPATA31D3	8.64e-04	19	105	2	9q21.32
Cytoband	17q25.1	SDK2 NT5C FOXJ1	8.71e-04	81	105	3	17q25.1
Cytoband	19q13.3	SIGLEC5 SLC8A2 MARK4	9.03e-04	82	105	3	19q13.3
Cytoband	1p32	ORC1 ERI3	1.75e-03	27	105	2	1p32
Cytoband	7p21.3	VWDE SCIN	1.88e-03	28	105	2	7p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	MYO1E DIS3L HERC1	3.52e-03	132	105	3	chr15q22
GeneFamily	Dyneins, axonemal	DNAH7 DNAH1 DNAH8	4.65e-05	17	76	3	536
GeneFamily	Cytochrome P450 family 26	CYP26A1 CYP26C1	5.22e-05	3	76	2	1013
GeneFamily	6-phosphofructo-2-kinases/fructose-2,6-biphosphatases	PFKFB2 PFKFB3	1.04e-04	4	76	2	1077
GeneFamily	CD molecules\|Activating leukocyte immunoglobulin like receptors	LILRA3 LILRA2	2.59e-04	6	76	2	1181
GeneFamily	EF-hand domain containing\|Plakins	DSP DST	4.80e-04	8	76	2	939
GeneFamily	Tudor domain containing	TDRD9 KDM4C TDRD6	5.00e-04	37	76	3	780
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEA	6.16e-04	9	76	2	1230
GeneFamily	EF-hand domain containing	ITSN1 DNAH7 RYR2 DST SLC25A12	2.29e-03	219	76	5	863
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP11 MMP17	4.53e-03	24	76	2	891
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	SIGLEC14 SIGLEC5	6.14e-03	28	76	2	745
Coexpression	PRC2_SUZ12_UP.V1_DN	CHRNA6 CRYBG2 LILRA3 MYOM1 ADCY2 ORC1 PAX1 FOXJ1	1.01e-06	192	104	8	M2740
Coexpression	GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN	MANBA DSP PPFIBP1 UGGT1 NT5C PROM1 SLC25A12 FDPS	1.32e-06	199	104	8	M7479
Coexpression	PETRETTO_BLOOD_PRESSURE_UP	MYO1E CHIT1 RYR2	1.30e-05	12	104	3	M14298
Coexpression	GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN	MYOM1 ITSN1 ITGA6 MECOM NBEA PFKFB2 CSNK1G3	1.54e-05	200	104	7	M7495
Coexpression	LAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX	MYO1E MECOM NBEA MED13L MAPK10 SCIN	2.14e-05	141	104	6	M39235
Coexpression	GOZGIT_ESR1_TARGETS_UP	PEG10 ITSN1 CYP26A1 VWDE ORC1 DST	2.93e-05	149	104	6	M13944
Coexpression	IBRAHIM_NRF2_DOWN	EPRS1 MANBA MECOM NT5C SEMA3B SHOC1	5.73e-05	168	104	6	M42513
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	MYO1E MECOM PFKFB3 MED13L ITPR2 CACNA2D3	5.92e-05	169	104	6	M39230
Coexpression	GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP	DNAJC13 SDK2 DIS3L PCDHB2 FDPS MAPK10	1.10e-04	189	104	6	M6588
Coexpression	GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP	EPRS1 UGGT1 NDUFA2 NT5C MSL3 HERC1	1.38e-04	197	104	6	M5332
Coexpression	GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	GALT DIPK1A NBEA PKHD1L1 MAP3K1 MSL3	1.41e-04	198	104	6	M6518
Coexpression	GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_UP	MYO1E SIGLEC5 IRF4 FDPS SEMA3B MSL3	1.41e-04	198	104	6	M5541
Coexpression	GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_UP	DNAJC13 ITGA6 NT5C POLR3E LRP5 GDPGP1	1.45e-04	199	104	6	M8748
Coexpression	GSE13306_TREG_VS_TCONV_SPLEEN_UP	ELAPOR2 CHRNA6 MYOM1 CYP26A1 NBEA DNAH7	1.49e-04	200	104	6	M3224
Coexpression	GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_DN	IRF4 NBEA MAP3K1 MAPK10 GDPGP1 DNAH8	1.49e-04	200	104	6	M9935
Coexpression	GSE21379_WT_VS_SAP_KO_CD4_TCELL_UP	MYOM1 MYO1E ITGA6 IRF4 PROM1 FOXJ1	1.49e-04	200	104	6	M7499
Coexpression	GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN	EPRS1 HTR3A MYO1E ORC1 POLR3E SCFD1	1.49e-04	200	104	6	M3199
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C11orf16 DNAH7 DNAH1 PROM1 GALNT8 MAPK10 FOXJ1	2.21e-07	178	105	7	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B ISLR2 DSP CNTNAP3 ITGA6 PKHD1L1 MMP17	2.30e-07	179	105	7	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B ISLR2 DSP CNTNAP3 ITGA6 PKHD1L1 MMP17	2.30e-07	179	105	7	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	MYO1E MECOM PFKFB3 PROM1 ADAMTS16 MAPK10 SCIN	3.83e-07	193	105	7	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ISLR2 DSP PPFIBP1 CNTNAP3 ITGA6 PKHD1L1 MMP17	3.96e-07	194	105	7	bc03d0f8dca9f4ba10db2f2274293f8b119e8951
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ISLR2 DSP PPFIBP1 CNTNAP3 ITGA6 PKHD1L1 MMP17	3.96e-07	194	105	7	640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCell	wk_15-18-Endothelial-Lymph_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ISLR2 DSP PPFIBP1 CNTNAP3 ITGA6 PKHD1L1 MMP17	4.24e-07	196	105	7	ff627244d7f5fd6a2ec009dae32d3509f0e2d95e
ToppCell	proximal-Epithelial-Ionocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SDK2 CYP26A1 C11orf16 ITPR2 CYP26C1 MMP11 SCIN	4.39e-07	197	105	7	f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCell	proximal-Epithelial-Ionocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SDK2 CYP26A1 C11orf16 ITPR2 CYP26C1 MMP11 SCIN	4.39e-07	197	105	7	e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCell	proximal-3-Epithelial-Ionocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SDK2 CYP26A1 C11orf16 ITPR2 CYP26C1 MMP11 SCIN	4.39e-07	197	105	7	288492fc67d8e81349d38e82caf1f1890276b299
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	KDM4C STXBP5 MECOM NBEA MED13L ITPR2 HERC1	4.70e-07	199	105	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HTR3A PPFIBP1 PEG10 PKHD1L1 GALNT8 SCIN	7.88e-07	134	105	6	8707210b2a5d33baa1d204e9e2ed8921181cb309
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 ADCY2 RYR2 TDRD6 HEPHL1 CACNA2D3	2.22e-06	160	105	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1L1 ADCY2 RYR2 TDRD6 HEPHL1 CACNA2D3	2.22e-06	160	105	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	HTR3A PPFIBP1 IRF4 PFKFB2 PFKFB3 DST	3.84e-06	176	105	6	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	wk_20-22-Hematologic-Myeloid-pre-pDC/DC5\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LILRA2 HTR3A MYO1E SIGLEC14 SIGLEC5 IRF4	3.97e-06	177	105	6	6de3c623f8595d7e3827df99b806bc9f1f15b3b7
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 SDK2 UGGT1 PFKFB2 DST HERC1	4.10e-06	178	105	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B ISLR2 PPFIBP1 CNTNAP3 PKHD1L1 DST	4.66e-06	182	105	6	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B ISLR2 PPFIBP1 CNTNAP3 ITGA6 PKHD1L1	5.12e-06	185	105	6	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B ISLR2 DSP CNTNAP3 PKHD1L1 MMP17	5.12e-06	185	105	6	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B ISLR2 DSP CNTNAP3 PKHD1L1 MMP17	5.12e-06	185	105	6	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B MYO1E STXBP5 MECOM PFKFB3 MAPK10	5.44e-06	187	105	6	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA6 MECOM PFKFB3 ADAMTS16 SHOC1 SCIN	5.96e-06	190	105	6	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E MECOM PFKFB3 ADAMTS16 MAPK10 SCIN	5.96e-06	190	105	6	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 ITGA6 MECOM MAPK10 SCIN ACOXL	6.14e-06	191	105	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIBP1 PFKFB3 DNAH7 MAP3K1 PROM1 CACNA2D3	6.14e-06	191	105	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	wk_20-22-Endothelial-Lymph_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ISLR2 DSP PPFIBP1 CNTNAP3 ITGA6 PKHD1L1	6.14e-06	191	105	6	631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ELAPOR2 MECOM PFKFB2 FDPS MAPK10 ACOXL	6.33e-06	192	105	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ELAPOR2 MECOM PFKFB2 FDPS MAPK10 ACOXL	6.33e-06	192	105	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E MECOM DNAH7 MAP3K1 PROM1 CACNA2D3	6.52e-06	193	105	6	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E MECOM DNAH7 MAP3K1 PROM1 CACNA2D3	6.52e-06	193	105	6	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NBEA C11orf16 DNAH7 PROM1 SHOC1 MAPK10	6.72e-06	194	105	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	distal-Hematologic-Platelet/Megakaryocyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSP C11orf16 DNAH7 PROM1 PAX1 FOXJ1	7.33e-06	197	105	6	751ffb8792058384079ebfe94872b3525f1aea84
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CYP26A1 PCDHB2 ITGA6 DST CYP26C1 SCIN	7.55e-06	198	105	6	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CRYBG2 TDRD9 DSP DNAH7 DNAH1 HEPHL1	7.55e-06	198	105	6	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	CRYBG2 TDRD9 DSP DNAH7 DNAH1 HEPHL1	7.55e-06	198	105	6	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	91308b255783ad4029e5575028c18d7550832c51
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MECOM C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	7.77e-06	199	105	6	72689bda7476930887ae007682fcab27f956f050
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TDRD9 DNAH7 ADCY2 DNAH1 PROM1 FOXJ1	7.99e-06	200	105	6	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-9\|TCGA-Kidney / Sample_Type by Project: Shred V9	CYP26A1 SLC25A12 CYP26C1 HERC1 ACOXL	1.54e-05	132	105	5	f1ef63a4842ab6ca584a9dcc2dd5b2108fc990aa
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYO1E DIPK1A DST ADGRF3 CACNA2D3	3.13e-05	153	105	5	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYO1E DIPK1A DST ADGRF3 CACNA2D3	3.13e-05	153	105	5	f17f62646633cf95c810dcd5328978058741b276
ToppCell	Paneth_cell\|World / shred on cell type and cluster	CNTNAP3B FGFRL1 ITPR2 PROM1 DNAH8	3.87e-05	160	105	5	d787b7cdb8c3f677ac9c4934a5df9cc194df3987
ToppCell	C_07\|World / shred on cell type and cluster	CNTNAP3B FGFRL1 ITPR2 PROM1 DNAH8	3.87e-05	160	105	5	b7c5a8a1c85da92e1945721b6887b32fad7b76b8
ToppCell	Control\|World / group, cell type (main and fine annotations)	MECOM MAPK10 PACSIN2 CACNA2D3 ACOXL	4.88e-05	168	105	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B DSP PPFIBP1 PKHD1L1 LRP5	4.88e-05	168	105	5	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B DSP PPFIBP1 PKHD1L1 LRP5	4.88e-05	168	105	5	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B DSP PPFIBP1 CNTNAP3 PKHD1L1	5.61e-05	173	105	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3A SIGLEC5 IRF4 PFKFB2 CACNA2D3	5.77e-05	174	105	5	4120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 SDK2 KDM4C PFKFB2 HERC1	5.77e-05	174	105	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	HTR3A PPFIBP1 IRF4 PFKFB2 DST	5.77e-05	174	105	5	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP STXBP5 BRINP1 ADCY2 CRYBA2	5.93e-05	175	105	5	97a58bc6ed2e8e359283d4214172c990c6e3755e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	DNAH7 CRYBA2 ADAMTS16 SCIN FOXJ1	6.09e-05	176	105	5	8e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 CNTNAP3 PKHD1L1 CYP26C1 MMP17	6.09e-05	176	105	5	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FGFRL1 ADCY2 DNAH1 PROM1 SLC25A12	6.43e-05	178	105	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HTR3A MYO1E IRF4 PFKFB2 MMP11	6.60e-05	179	105	5	124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SDK2 CNTNAP3 SLC8A2 MMP17	6.60e-05	179	105	5	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HTR3A MYO1E IRF4 PFKFB2 MMP11	6.60e-05	179	105	5	edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CNTNAP3B CNTNAP3 RYR2 SHOC1 CACNA2D3	6.60e-05	179	105	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SDK2 CNTNAP3 SLC8A2 MMP17	6.77e-05	180	105	5	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B DSP PPFIBP1 CNTNAP3 PKHD1L1	6.95e-05	181	105	5	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	3'_v3-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	SDK2 IRF4 PFKFB2 SPATA31D3 MMP11	6.95e-05	181	105	5	3d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B DSP PPFIBP1 CNTNAP3 PKHD1L1	6.95e-05	181	105	5	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIBP1 BRINP1 MAP3K1 PROM1 CACNA2D3	6.95e-05	181	105	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP26A1 ITPR2 CYP26C1 MMP11 SCIN	7.14e-05	182	105	5	6e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIBP1 BRINP1 MAP3K1 PROM1 CACNA2D3	7.14e-05	182	105	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 CYP26A1 SEMA3B SCIN MMP17	7.14e-05	182	105	5	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP26A1 ITPR2 CYP26C1 MMP11 SCIN	7.14e-05	182	105	5	cd972d30519db706477c6b0c901165b81b74abed
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B PPFIBP1 CNTNAP3 PKHD1L1 DST	7.32e-05	183	105	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B STXBP5 MECOM MAPK10 SCIN	7.32e-05	183	105	5	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	ITGA6 MECOM ITPR2 SHOC1 SCIN	7.32e-05	183	105	5	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB PKHD1L1 RYR2 DNAH1 ADAMTS16	7.51e-05	184	105	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB PKHD1L1 RYR2 DNAH1 ADAMTS16	7.51e-05	184	105	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB PKHD1L1 RYR2 DNAH1 ADAMTS16	7.51e-05	184	105	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SDK2 FGFRL1 ADCY2 GALNT8 CACNA2D3	7.71e-05	185	105	5	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SDK2 FGFRL1 ADCY2 GALNT8 CACNA2D3	7.71e-05	185	105	5	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B PPFIBP1 CNTNAP3 PKHD1L1 DST	7.91e-05	186	105	5	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 DSP RYR2 MAPK10 CACNA2D3	7.91e-05	186	105	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 DSP RYR2 MAPK10 CACNA2D3	7.91e-05	186	105	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA6 MECOM ITPR2 DST SHOC1	7.91e-05	186	105	5	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SDK2 DSP CNTNAP3 PROM1 MMP11	7.91e-05	186	105	5	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	C11orf16 DNAH7 PROM1 MAPK10 FOXJ1	8.11e-05	187	105	5	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 MECOM PFKFB2 SCIN ACOXL	8.11e-05	187	105	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELAPOR2 SDK2 DSP SEMA3B CACNA2D3	8.11e-05	187	105	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM PFKFB3 ADAMTS16 MAPK10 SCIN	8.11e-05	187	105	5	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA6 MECOM ITPR2 DST SCIN	8.32e-05	188	105	5	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MECOM PROM1 ADAMTS16 MAPK10 SCIN	8.32e-05	188	105	5	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B PPFIBP1 CNTNAP3 ITGA6 PKHD1L1	8.53e-05	189	105	5	0d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 MECOM PKHD1L1 ITPR2	8.53e-05	189	105	5	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIBP1 PFKFB3 DNAH7 MAP3K1 PROM1	8.53e-05	189	105	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B DSP PPFIBP1 CNTNAP3 PKHD1L1	8.74e-05	190	105	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DNAH7 MAP3K1 PROM1 CACNA2D3	8.74e-05	190	105	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ISLR2 PPFIBP1 CNTNAP3 PKHD1L1 MAP3K1	8.74e-05	190	105	5	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DSP PPFIBP1 CNTNAP3 ITGA6 PKHD1L1	8.74e-05	190	105	5	103e78c2233c3ee0c215a9dafe70705477e9ee5e
Disease	FEV/FEC ratio	DSP DIPK1A MECOM IRF1 BRINP1 MEAK7 ADCY2 MAP3K1 USP8 DST HERC1 MAPK10 CACNA2D3	2.35e-04	1228	99	13	EFO_0004713
Disease	urate measurement, bone density	PPFIBP1 DNAH1 ITPR2 POLR3E MARK4 ADAMTS16 SCFD1 DNAH8 NUP153	2.40e-04	619	99	9	EFO_0003923, EFO_0004531
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	3.08e-04	8	99	2	DOID:0060308 (implicated_via_orthology)
Disease	apolipoprotein B measurement	ARHGEF19 DNAJC13 CYP26A1 APOB USP8 CSNK1G3 FER1L4 MARK4 CYP26C1	3.97e-04	663	99	9	EFO_0004615
Disease	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement	SIGLEC14 SIGLEC5	4.93e-04	10	99	2	EFO_0801544
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	DSP RYR2	4.93e-04	10	99	2	DOID:0050431 (is_implicated_in)
Disease	alopecia areata	IRF4 PFKFB3 ACOXL	6.40e-04	50	99	3	EFO_0004192
Disease	sialic acid-binding Ig-like lectin 14 measurement	SIGLEC14 SIGLEC5	7.20e-04	12	99	2	EFO_0008284
Disease	monocyte percentage of leukocytes	CRYBG2 MANBA CYP26A1 MECOM IRF4 MED13L USP8 MARK4 ACOXL	7.97e-04	731	99	9	EFO_0007989
Disease	Hypertrophic Cardiomyopathy	MYOM1 DSP RYR2	9.40e-04	57	99	3	C0007194
Disease	aspartate aminotransferase to alanine aminotransferase ratio	MECOM PFKFB2 USP8 MARK4 HEPHL1	1.29e-03	239	99	5	EFO_0010934
Disease	posterior cingulate cortex volume measurement	KDM4C ADCY2	1.47e-03	17	99	2	EFO_0010324
Disease	susceptibility to mononucleosis measurement	ADCY2 RYR2 DNAH8	1.63e-03	69	99	3	EFO_0008403
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3 NBEA BRINP1	1.74e-03	152	99	4	DOID:0060041 (implicated_via_orthology)
Disease	tissue plasminogen activator measurement, coronary artery disease	NBEAL1 STXBP5 APOB	1.77e-03	71	99	3	EFO_0001645, EFO_0004791
Disease	obsolete_red blood cell distribution width	DNAJC13 DIPK1A ITSN1 MECOM IRF1 APOB MAP3K1 CSNK1G3 MARK4 LRP5 HERC1 ACOXL	1.84e-03	1347	99	12	EFO_0005192
Disease	Abnormality of refraction	SMG1 DNAJC13 TDRD9 NBEA ITPR2 SLC25A12 FER1L4 GALNT8	1.95e-03	673	99	8	HP_0000539
Disease	polymyositis	SDK2 LRP5	2.04e-03	20	99	2	EFO_0003063
Disease	amino acid measurement	MYO1E CNTNAP3 CHIT1 DNAH7 RYR2 MARK4 CYP26C1 MAPK10	2.04e-03	678	99	8	EFO_0005134
Disease	white matter microstructure measurement	SDK2 NBEAL1 MECOM APOB NDUFA2 CACNA2D3	2.05e-03	390	99	6	EFO_0005674
Disease	citrate measurement	CYP26A1 PFKFB2 PFKFB3	2.41e-03	79	99	3	EFO_0010114
Disease	Colorectal Carcinoma	RBP3 APOB BRINP1 NT5C PROM1 ZNF432 MMP11 DNAH8	2.53e-03	702	99	8	C0009402
Disease	vasculitis	KDM4C IRF1	2.93e-03	24	99	2	EFO_0006803
Disease	attempted suicide	ELAPOR2 PROM1 DNAH8 CACNA2D3	3.09e-03	178	99	4	EFO_0004321
Disease	urinary albumin to creatinine ratio	MYOM1 CYP26A1 IRF1 ACOXL	3.15e-03	179	99	4	EFO_0007778

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGLPVADYFKQWINL	ERI3	261	O43414
YLNWIGVPTKVFNLG	PFKFB2	61	O60825
AQGFKWNLYEVVRVP	ADGRF3	316	Q8IZF5
KQYRREESIWGFPGN	CNTNAP3	121	Q9BZ76
EFGYPRWEKIRLQNS	BRINP1	581	O60477
QGEWELLGVLPYFRE	HTR3A	206	P46098
QQFILEKGDYPRWSA	CRYBA2	66	P53672
RYIRVNWNEILPGFE	ASTL	201	Q6HA08
ELLFQGRNPGVAWEY	ADAMTS16	841	Q8TE57
QYEEKPLFGLLQNWA	ACOXL	396	Q9NUZ1
VEEGVNAYWFRGLRP	ISLR2	546	Q6UXK2
HEWIDLIFGYKQRGP	NBEAL1	2216	Q6ZS30
EKYRWVEQHLGPQFV	NT5C	111	Q8TCD5
VKFWQIYIEGQDEPR	EDC4	321	Q6P2E9
WQPTNVDGKGYLLNE	IRF1	246	P10914
ALGGPAWDYRNIIEK	ITPR2	1591	Q14571
YQLLKATEPGLFGVW	PCDHB2	606	Q9Y5E7
YQLLKATEPGLFGVW	PCDHB18P	551	Q96TA0
YKEGERDFLQRPGWQ	LILRA2	256	Q8N149
QPDVGSWLKYIRFAG	MECOM	141	Q03112
VRLADGEKGWVPQAY	ARHGEF19	756	Q8IW93
KVPYIFRDNQWVGFD	CHIT1	321	Q13231
QLFAEEWGQYVDLPK	ISOC1	71	Q96CN7
DKNFVRIGKWFVRPY	MED13L	136	Q71F56
ILFPGRDYIDQWNKV	MAPK10	261	P53779
QWLIDQIDSGKYPGL	IRF4	26	Q15306
RWLDDIGLPQYKTQF	PPFIBP1	726	Q86W92
WIEFGRIKLLQGYHP	DST	341	Q03001
QICWYQKPGVGLDAI	FDPS	181	P14324
EDWLNVFPLYRGQGG	FER1L4	1186	A9Z1Z3
PWNGSVGEKLRDVIY	HERC1	1041	Q15751
PLDKFIYWVDGRQNI	LRP5	986	O75197
PVIQWLKRVEYGAEG	FGFRL1	276	Q8N441
WIGVPTKVFNVGEYR	PFKFB3	61	Q16875
QERRKFGPLGWNIPY	DNAH8	4061	Q96JB1
GRKIPEYLIHFNGWN	MSL3	46	Q8N5Y2
EYVAQNGIPLRIKDW	PEG10	381	Q86TG7
FQPDRYQLWKQGKDI	KDM4C	326	Q9H3R0
WGRQTIPDFVYGQKD	GDPGP1	21	Q6ZNW5
KDGWQDIVIGAPQYF	ITGA6	366	P23229
QDGKRLLGPQWLDYD	MEAK7	176	Q6P9B6
YFLRGSLPWQGLKAD	CSNK1G3	241	Q9Y6M4
KRGFQETLYVWNEPK	ELAPOR2	891	A8MWY0
HLLGRKPGAQEIFWY	ORC1	101	Q13415
IRDYKQGDPGIFAWE	PAX1	181	P15863
WRQLVEKGPQYGTVE	PACSIN2	66	Q9UNF0
VEEYIPKWEQFLLGR	C3orf14	91	Q9HBI5
LPGIWDQYLDQFQKL	DNAH1	3611	Q9P2D7
WKPDIVLYNNAVGDF	CHRNA6	116	Q15825
GDYSQVLFERPGIWK	ADCY2	786	Q08462
NKALYWVNGQVPDGV	APOB	716	P04114
FRQYPGIKWEPDENG	CACNA2D3	221	Q8IZS8
IYWDFKPGGAVINRD	GALNT8	581	Q9NY28
LGAQYPWVQIFENKG	GALT	161	P07902
GILQKNWRDYVVTFP	DIS3L	336	Q8TF46
KWLPYEAGQRFLEFQ	DSP	2716	P15924
EKVEGLQAQALYPWR	ITSN1	911	Q15811
WVLYEEPEFRGQKLV	CRYBG2	1026	Q8N1P7
ARLKFLQQWYEVGPP	DNAH7	3856	Q8WXX0
KGGFWRIDPQYAERL	FOXJ1	191	Q92949
LRTFELDGYQIPKGW	CYP26C1	391	Q6V0L0
YGKFNKVPEWQRLAG	DNAJC13	691	O75165
FPTQGIWKDVRIEAY	MANBA	196	O00462
IGIVEEYWNYVPQGK	HEPHL1	31	Q6MZM0
LFQGKKYDGPEVDIW	MARK4	226	Q96L34
FELNGYQIPKGWNVI	CYP26A1	381	O43174
YLGIWDNLPGVVKCQ	DIPK1A	101	Q5T7M9
NGINQGYKLIAWEPE	SDK2	821	Q58EX2
NKIELGWQYGPVRDD	RYR2	896	Q92736
VVRINKGWEFILPYD	POLR3E	391	Q9NVU0
KQYRREESIWGFPGN	CNTNAP3B	121	Q96NU0
VLYKEWGRDFLQRPG	LILRA3	256	Q8N6C8
PYREDTEWLKGQQIG	MAP3K1	1236	Q13233
LVWGPEKNKIYFFRG	MMP11	391	P24347
VQPKLWARYAFGQET	NDUFA2	61	O43678
IPGEKQFAYQNSWGL	EPRS1	1261	P07814
DGNWYRGIVIEKEPK	TDRD6	1046	O60522
QTGELRYPKDELNWG	TDRD9	676	Q8NDG6
GLPYEDKVRVWQLYG	MMP17	281	Q9ULZ9
FVLKLPQNSGYIWVG	SCIN	541	Q9Y6U3
QWIDLIFGYKQRGPE	NBEA	2496	Q8NFP9
QWVDGATPLFGLYKR	SMG1	2206	Q96Q15
ATPLFGLYKRWQQRE	SMG1	2211	Q96Q15
YIIDPLNLFWFGIGK	PROM1	786	O43490
WGGSLQEKPVYELQV	SIGLEC5	11	O15389
GPYLGDIWRQLEIVQ	SHOC1	696	Q5VXU9
DHLEQKYVQLFWGLP	SPATA31D4	491	Q6ZUB0
PFQSKWLYVGTERGN	STXBP5	151	Q5T5C0
LQRWFYIDFGGLKPA	SLC25A12	601	O75746
GDKVLALWEPGQQQY	C11orf16	156	Q9NQ32
YVAFINEWRILPGKS	VWDE	591	Q8N2E2
DHLEQKYVQLFWGLP	SPATA31D3	491	P0C874
WTLPQVLGERYGADK	RBP3	211	P10745
KLWYRDFLQLVEPGG	SEMA3B	686	Q13214
PVWKVLIYDRFGQDI	SCFD1	41	Q8WVM8
PGKHDIYVEVRNWGF	PKHD1L1	1301	Q86WI1
VPGWLQRYFNKNEDV	NUP153	51	P49790
IAQDLWPEQGIKDYF	ZNF730	81	Q6ZMV8
WPEQGIKDYFQEVIL	ZNF730	86	Q6ZMV8
EWQLLGPFQKDLYRD	ZNF432	21	O94892
LIQYVQRPLGWVGVF	TRIM64C	396	A6NLI5
QRPLGWVGVFLDYDN	TRIM64C	401	A6NLI5
RNEPLVLEGGYENWL	USP8	291	P40818
WGGSLQEKPVYELQV	SIGLEC14	11	Q08ET2
LGYFQLKANPGAWIL	UGGT1	1151	Q9NYU2
QLFGVDYRPVLRWEQ	HECTD3	166	Q5T447
NFFIELGQPQWLKRG	SLC8A2	606	Q9UPR5
EGIRWTPIEYFNNKI	MYO1E	431	Q12965
NYREVIDGVPGKWRE	MYOM1	971	P52179