Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

3.21e-07181695GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

3.44e-06281695GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.43e-05371695GO:0045505
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH7 MYH7B DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

6.58e-051181697GO:0003774
GeneOntologyMolecularFunctionpolysaccharide binding

CLEC18A CLEC18B CLEC18C AGL

1.30e-04311694GO:0030247
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

3.18e-04701695GO:0003777
GeneOntologyMolecularFunctionDNA topoisomerase type I (single strand cut, ATP-independent) activity

TOP3B TOP1

4.23e-0441692GO:0003917
GeneOntologyMolecularFunctionstructural constituent of muscle

OBSCN DMD MYBPC1 MYBPC2

4.72e-04431694GO:0008307
GeneOntologyBiologicalProcesscellular anatomical entity morphogenesis

MYH7 SLC9A8 KIAA0319L OBSCN EP300 VPS13B MYBPC1 MYBPC2

4.65e-051561708GO:0032989
GeneOntologyBiologicalProcesscellular component assembly involved in morphogenesis

MYH7 SLC9A8 KIAA0319L OBSCN EP300 VPS13B MYBPC1 MYBPC2

4.65e-051561708GO:0010927
GeneOntologyBiologicalProcesscilium movement involved in cell motility

TTLL3 KIAA0319L DNAH14 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

6.35e-052101709GO:0060294
GeneOntologyBiologicalProcesscilium movement

TTLL3 KIAA0319L DNAH14 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 JHY DNAH11

6.39e-0526117010GO:0003341
GeneOntologyBiologicalProcesscilium-dependent cell motility

TTLL3 KIAA0319L DNAH14 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

7.61e-052151709GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

TTLL3 KIAA0319L DNAH14 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

7.61e-052151709GO:0001539
GeneOntologyBiologicalProcessstriated muscle cell development

MYH7 OBSCN DMD EP300 MYBPC1 MYBPC2

9.47e-05891706GO:0055002
GeneOntologyBiologicalProcesssarcomere organization

MYH7 OBSCN EP300 MYBPC1 MYBPC2

1.25e-04591705GO:0045214
GeneOntologyBiologicalProcesschromatin remodeling

ATR RBBP4 RBBP7 NSD2 CHD9 BCL7A BCOR ZBTB7A CBX5 NFRKB CDYL MAEL KDM4A APOBEC3C CDK1 TOP1 EP300

1.39e-0474117017GO:0006338
GeneOntologyCellularComponentmyosin filament

MYH7 MYH7B OBSCN MYBPC1 MYBPC2

1.47e-06251685GO:0032982
GeneOntologyCellularComponentdynein complex

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

7.27e-05541685GO:0030286
GeneOntologyCellularComponentRZZ complex

ZWILCH ZW10

1.92e-0431682GO:1990423
GeneOntologyCellularComponentmyofibril

MYH7 MYH7B OBSCN STYXL2 RYR2 MMP2 DMD MYBPC1 MYBPC2

3.76e-042731689GO:0030016
GeneOntologyCellularComponentsupramolecular fiber

ZWILCH MYH7 KRT9 TTLL3 DCDC1 MYH7B OBSCN STYXL2 DNAH14 RYR2 DNAH12 CDK1 MMP2 DMD ZW10 DNAH6 DNAH9 MYBPC1 DNAH11 COL1A1 MYBPC2

5.19e-04117916821GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

ZWILCH MYH7 KRT9 TTLL3 DCDC1 MYH7B OBSCN STYXL2 DNAH14 RYR2 DNAH12 CDK1 MMP2 DMD ZW10 DNAH6 DNAH9 MYBPC1 DNAH11 COL1A1 MYBPC2

5.67e-04118716821GO:0099081
GeneOntologyCellularComponentcontractile muscle fiber

MYH7 MYH7B OBSCN STYXL2 RYR2 MMP2 DMD MYBPC1 MYBPC2

5.82e-042901689GO:0043292
GeneOntologyCellularComponentA band

OBSCN RYR2 MYBPC1 MYBPC2

8.07e-04521684GO:0031672
GeneOntologyCellularComponentsarcomere

MYH7 OBSCN STYXL2 RYR2 MMP2 DMD MYBPC1 MYBPC2

9.38e-042491688GO:0030017
GeneOntologyCellularComponenthost intracellular region

GBP6 GBP4

9.43e-0461682GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP6 GBP4

9.43e-0461682GO:0030430
GeneOntologyCellularComponenthost cell part

GBP6 GBP4

9.43e-0461682GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP6 GBP4

9.43e-0461682GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP6 GBP4

9.43e-0461682GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP6 GBP4

9.43e-0461682GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP6 GBP4

9.43e-0461682GO:0020005
GeneOntologyCellularComponentaxonemal dynein complex

DNAH12 DNAH6 DNAH9

1.03e-03251683GO:0005858
GeneOntologyCellularComponentNURF complex

RBBP4 RBBP7

1.31e-0371682GO:0016589
GeneOntologyCellularComponentaxoneme

TTLL3 DNAH12 DNAH6 DNAH9 ODAD3 DNAH11 BRWD1

1.45e-032071687GO:0005930
GeneOntologyCellularComponentciliary plasm

TTLL3 DNAH12 DNAH6 DNAH9 ODAD3 DNAH11 BRWD1

1.50e-032081687GO:0097014
GeneOntologyCellularComponentM band

OBSCN MYBPC1 MYBPC2

1.94e-03311683GO:0031430
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.04e-07141685IPR024317
DomainAAA_8

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.04e-07141685PF12780
DomainDHC_fam

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.55e-07151685IPR026983
DomainDynein_heavy

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.55e-07151685PF03028
DomainDynein_heavy_dom

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

1.55e-07151685IPR004273
DomainDynein_HC_stalk

DNAH14 DNAH6 DNAH9 DNAH11

5.89e-06141684IPR024743
DomainDynein_heavy_dom-2

DNAH12 DNAH6 DNAH9 DNAH11

5.89e-06141684IPR013602
DomainDHC_N2

DNAH12 DNAH6 DNAH9 DNAH11

5.89e-06141684PF08393
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH6 DNAH9 DNAH11

5.89e-06141684IPR011704
DomainMT

DNAH14 DNAH6 DNAH9 DNAH11

5.89e-06141684PF12777
DomainAAA_5

DNAH12 DNAH6 DNAH9 DNAH11

5.89e-06141684PF07728
DomainCAF1C_H4-bd

RBBP4 RBBP7

2.40e-0431682PF12265
DomainHistone-bd_RBBP4_N

RBBP4 RBBP7

2.40e-0431682IPR022052
DomainCAP

CLEC18A CLEC18B CLEC18C

3.00e-04151683PF00188
DomainSCP

CLEC18A CLEC18B CLEC18C

3.00e-04151683SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18B CLEC18C

3.00e-04151683IPR001283
Domain-

CLEC18A CLEC18B CLEC18C

3.00e-041516833.40.33.10
DomainCAP_domain

CLEC18A CLEC18B CLEC18C

3.00e-04151683IPR014044
DomainAAA

ABCC1 ABCA7 DNAH12 DNAH6 TAP1 DNAH9 DNAH11

3.29e-041441687SM00382
DomainAAA+_ATPase

ABCC1 ABCA7 DNAH12 DNAH6 TAP1 DNAH9 DNAH11

3.29e-041441687IPR003593
DomainWD40_repeat_dom

RBBP4 RBBP7 UBR4 NOL11 EDC4 DCAF5 BRWD3 CFAP57 RIC1 BRWD1

3.67e-0429716810IPR017986
DomainGRAM

MTMR1 TBC1D8B GRAMD1B

3.67e-04161683SM00568
DomainKelch_1

KLHL10 KLHDC2 KLHL30 ATRNL1 KLHL34

4.19e-04701685PF01344
DomainKelch_1

KLHL10 KLHDC2 KLHL30 ATRNL1 KLHL34

4.19e-04701685IPR006652
DomainSHR-BD

VPS13C VPS13B

4.77e-0441682IPR009543
DomainCoact_PPARg

FAM120A FAM120C

4.77e-0441682IPR026784
DomainVPS13_C

VPS13C VPS13B

4.77e-0441682PF16909
DomainVPS13_C

VPS13C VPS13B

4.77e-0441682IPR031645
DomainSHR-BD

VPS13C VPS13B

4.77e-0441682PF06650
DomainAutophagy-rel_C

VPS13C VPS13B

7.90e-0451682IPR015412
DomainATG_C

VPS13C VPS13B

7.90e-0451682PF09333
Domain-

KLHDC2 KLHL30 ATRNL1 KLHL34

9.03e-044816842.120.10.80
DomainGRAM

MTMR1 TBC1D8B GRAMD1B

9.71e-04221683PF02893
DomainGRAM

MTMR1 TBC1D8B GRAMD1B

9.71e-04221683IPR004182
DomainChromo_domain

CHD9 CBX5 CDYL

1.26e-03241683IPR023780
DomainKelch-typ_b-propeller

KLHDC2 KLHL30 ATRNL1 KLHL34

1.51e-03551684IPR015915
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

OGFRL1 ZWILCH AKT3 TTLL3 TUT7 FRMPD1 OBSCN NOL11 BCOR DCAF5 GBP4 CANT1 TSR1 P4HB CBX5 ATRNL1 NFRKB MKX HSD3B1 ARHGAP21 VPS13B BRWD1

2.58e-0810841732211544199
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 EVL SLC9A8 TTLL3 RBBP4 NSD2 VPS13C FRMPD1 OBSCN EXOSC3 CHD9 BRWD3 DNAH14 GDE1 ZBTB7A PTPRB FAM120A FAM120C RIMS1 MMP16 COPS5 EP300 VPS13B RIC1 ZC3HAV1

1.06e-0714891732528611215
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18B CLEC18C

1.21e-073173326170455
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18B CLEC18C

1.21e-073173316336259
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18B CLEC18C

1.21e-073173333603190
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC1 ATR RBBP4 TUT7 KIAA0319L MCAM ABCA7 GDE1 GRAMD1B MYOF USP5 FAT1 CANT1 HNRNPUL2 P4HB PES1 FAM3C MMP2 IL1RAP TAP1 ARHGAP21 COL1A1

1.53e-0712011732235696571
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RBBP4 RBBP7 NSD2 CHD9 BCOR LIN9 GTF2F2 TSR1 CBX5 PES1 NFRKB CDYL KDM4A TOP1 BRWD1

4.42e-076081731536089195
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18A CLEC18B CLEC18C

4.82e-074173316709836
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

OBSCN EPB41L5 VAT1L KIAA1586 BCOR TRPM3 MED12L

7.74e-07101173710997877
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCDC1 RBBP4 RBBP7 NSD2 CHD9 BCL7A BCOR ABCA7 DCAF5 BRWD3 ZBTB7A FAT1 FAM120A FAM120C CBX5 CAPRIN2 NFRKB TOP1 EP300 BRWD1

8.25e-0711161732031753913
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

NSD2 EXOSC3 NOL11 DBP EDC4 TSR1 CBX5 PES1 APOBEC3C CDK1 ZC3HAV1

9.69e-073321731125693804
Pubmed

Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.

DMD MYBPC1 MYBPC2

1.20e-065173310024132
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

ABCC1 AKT3 RBBP4 RBBP7 TTI2 UBR4 EXOSC3 EDC4 GRAMD1B MYOF USP5 FAM120A ADSS2 HNRNPUL2 PES1 MKX PTRH2 GID8 CDK1 ZW10 TAP1 ZC3HAV1

3.10e-0614401732230833792
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH7 GBP6 ATR RBBP4 RBBP7 NOL11 GRAMD1B MYOF PTPN3 GTF2F2 CSK CDK1 UQCR11 MAPK13 COPS5 ARHGAP21 EP300

3.35e-069101731736736316
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ATR RBBP4 RBBP7 NSD2 UBR4 NOL11 CHD9 USP5 GTF2F2 ADSS2 HNRNPUL2 TSR1 CBX5 PES1 CDK1 TOP1 CWF19L1 EP300

3.45e-0610141731832416067
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RBBP4 RBBP7 NSD2 TUT7 UBR4 NOL11 EDC4 USP5 FAM120A TSR1 P4HB PES1 TOP1 ZC3HAV1

5.48e-066531731422586326
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

ATR UBR4 STYXL2 USP5 CDK1

1.06e-0558173531067491
Pubmed

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis.

RBBP4 RBBP7 CDK1 EP300

1.10e-0528173434163012
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

SLC9A8 GBP6 RBBP4 RBBP7 CHD9 EDC4 FAM120A TSR1 P4HB GID8 CDK1 MMP2 DMD TOP1 ARHGAP21

1.41e-058091731532129710
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MACC1 RBBP7 NSD2 EXOSC3 EPB41L5 NOL11 EDC4 BCL7A BCOR LIN9 ZBTB7A MYOF GTF2F2 TSR1 P4HB FAM120C PES1 NFRKB PTRH2 CDYL ZC3HAV1

1.90e-0514971732131527615
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

AKT3 RBBP4 RBBP7 TUT7 ADSS2 TRPM3 CSK P4HB CDK1 MMP2 MAPK13 MMP16 EP300 DNAH11

1.90e-057301731434857952
Pubmed

The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.

BCOR ZBTB7A CBX5

1.94e-0511173323658227
Pubmed

Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy.

RYR2 DMD

2.46e-052173226555638
Pubmed

Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition.

MYOF MMP2

2.46e-052173229164766
Pubmed

Fast and slow skeletal myosin binding protein-C and aging.

MYBPC1 MYBPC2

2.46e-052173236409445
Pubmed

Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts.

MMP2 DMD

2.46e-052173218669618
Pubmed

Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes.

RBBP4 RBBP7

2.46e-052173212376095
Pubmed

Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability.

ABCC1 ABCA7

2.46e-052173231189668
Pubmed

Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review).

RBBP4 RBBP7

2.46e-052173238577935
Pubmed

Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.

PRUNE2 OBSCN

2.46e-052173217360660
Pubmed

The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice.

RYR2 DMD

2.46e-052173219298530
Pubmed

D-site binding protein transactivation requires the proline- and acid-rich domain and involves the coactivator p300.

DBP EP300

2.46e-052173210364202
Pubmed

Type I collagen stabilization of matrix metalloproteinase-2.

MMP2 COL1A1

2.46e-052173211368514
Pubmed

ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.

ATR TOP1

2.46e-052173225269479
Pubmed

Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment.

MYBPC1 MYBPC2

2.46e-05217328375400
Pubmed

ZBTB7A Suppresses Melanoma Metastasis by Transcriptionally Repressing MCAM.

MCAM ZBTB7A

2.46e-052173225995384
Pubmed

Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain.

MYBPC1 MYBPC2

2.46e-05217329252413
Pubmed

Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A).

MMP2 MMP16

2.46e-052173217217338
Pubmed

RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.

RBBP4 EP300

2.46e-052173235231103
Pubmed

Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.

MMP2 DMD

2.46e-052173221320869
Pubmed

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.

RBBP4 RBBP7

2.46e-052173234709113
Pubmed

YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.

YTHDF1 GID8

2.46e-052173239151722
Pubmed

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.

RYR2 DMD

2.46e-052173230181262
Pubmed

Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development.

MMP2 COL1A1

2.46e-052173217440987
Pubmed

Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation.

MMP2 DMD

2.46e-052173232208990
Pubmed

ZBTB7A suppresses glioblastoma tumorigenesis through the transcriptional repression of EPB41L5.

EPB41L5 ZBTB7A

2.46e-052173236596853
Pubmed

SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes.

RBBP7 DCAF5 COPS5

2.57e-0512173328886238
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RBBP7 UBR4 EPB41L5 MTMR1 USP5 PTPN3 FAM120A CSK HNRNPUL2 P4HB AGL PTRH2 GID8 CDK1 DMD ZC3HAV1

3.17e-059741731628675297
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EVL PACSIN1 RBBP7 MTMR1 ACTR3B EDC4 GRAMD1B USP5 FAM120A C12orf50 HNRNPUL2 P4HB FAM120C RIMS1 FGG DMD DNAH6 TOP1 ARHGAP21 DNAH11

3.21e-0514311732037142655
Pubmed

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.

MYH7 MYH7B EP300

3.33e-0513173324565863
Pubmed

Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.

CLEC18A CLEC18B CLEC18C COL1A1

3.44e-0537173422432025
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EVL MACC1 MYH7 PDE6A NSD2 MYH7B UBR4 RYR2 P4HB CBX5 PES1 CAPRIN2 RIMS1 DMD DNAH6 TOP3B TOP1 ARHGAP21 MYBPC1 MYBPC2

3.57e-0514421732035575683
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

RBBP4 RBBP7 DNAH9 EP300 BRWD1

3.74e-0575173525593309
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH6 DNAH11

4.23e-051417339373155
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH7 OBSCN FAM120A P4HB CBX5 AGL MED12L MMP2 ARHGAP21 MYBPC1 MYBPC2

4.29e-054971731123414517
Pubmed

Proteomic analysis identifies novel binding partners of BAP1.

KLHDC2 RBBP4 RBBP7 FAT1 CBX5

5.11e-0580173534591877
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

KRT9 RBBP7 YTHDF1 FAM120A HNRNPUL2 TSR1 PTRH2 FGG TOP1 COL1A1

5.35e-054211731034650049
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

EVL RBBP4 RBBP7 TUT7 TBC1D8B USP5 GTF2F2 FAM120A CSK CBX5 TOP1 CWF19L1 ZC3HAV1

5.36e-057011731330196744
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

RBBP4 NOL11 BCOR LIN9 GTF2F2 TSR1 PES1 NFRKB TOP1

5.46e-05339173930415952
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT9 RBBP4 TUT7 EXOSC3 NOL11 EDC4 MYOF PTPN3 GTF2F2 FAM120A HNRNPUL2 TSR1 P4HB PES1 CDK1 TOP1 ZC3HAV1 COL1A1

5.99e-0512571731836526897
Pubmed

Structure-function relationship of Vpr: biological implications.

ATR CDK1 EP300

6.46e-0516173319275588
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MYH7 KRT9 RBBP4 RBBP7 UBR4 EXOSC3 MTMR1 AKR1A1 USP5 FAM120A TSR1 P4HB AGL CDK1 ZW10 TOP1 ZC3HAV1

6.52e-0511491731735446349
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

KRT9 RBBP4 RBBP7 CHD9 EDC4 YTHDF1 FAM120A HNRNPUL2 TSR1 P4HB CBX5 AGL CDK1 ZW10 TOP1 ZC3HAV1 COL1A1

6.81e-0511531731729845934
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

RBBP7 NSD2 EXOSC3 NOL11 FAM120A TSR1 CBX5 PES1 ZC3HAV1

6.82e-05349173925665578
Pubmed

Increased matrix-metalloproteinase-2 and matrix-metalloproteinase-9 expression in the brain of dystrophic mdx mouse.

MMP2 DMD

7.36e-053173216650610
Pubmed

Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR-377/VE-PTP axis.

PTPRB COL1A1

7.36e-053173230044046
Pubmed

Comparative analysis of basal lamina type IV collagen α chains, matrix metalloproteinases-2 and -9 expressions in oral dysplasia and invasive carcinoma.

MMP2 COL1A1

7.36e-053173222694915
Pubmed

Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

RBBP4 RBBP7

7.36e-05317327503932
Pubmed

Knockdown of MACC1 expression suppressed hepatocellular carcinoma cell migration and invasion and inhibited expression of MMP2 and MMP9.

MACC1 MMP2

7.36e-053173223232575
Pubmed

p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint.

ATR EP300

7.36e-053173217272271
Pubmed

An intrinsic S/G2 checkpoint enforced by ATR.

ATR CDK1

7.36e-053173230139873
Pubmed

Defective folding and stable association with protein disulfide isomerase/prolyl hydroxylase of type I procollagen with a deletion in the pro alpha 2(I) chain that preserves the Gly-X-Y repeat pattern.

P4HB COL1A1

7.36e-05317321339453
Pubmed

Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.

PTRH2 MMP2

7.36e-053173228488526
Pubmed

miR-582-5p inhibits proliferation of hepatocellular carcinoma by targeting CDK1 and AKT3.

AKT3 CDK1

7.36e-053173226002580
Pubmed

Structure of the RZZ complex and molecular basis of its interaction with Spindly.

ZWILCH ZW10

7.36e-053173228320825
Pubmed

Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.

RYR2 DMD

7.36e-053173220615971
Pubmed

The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression.

RBBP4 RBBP7

7.36e-053173218577416
Pubmed

A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice.

AKT3 FCGR2A

7.36e-053173221159799
Pubmed

Effects of combined Pulsed Dye Laser and Fractional CO2 Laser treatment of burn scars and correlation with plasma levels of collagen type I, MMP-2 and TIMP-1.

MMP2 COL1A1

7.36e-053173233358398
Pubmed

Expression of matrix metalloproteinases 2 and 9 in regenerating skeletal muscle: a study in experimentally injured and mdx muscles.

MMP2 DMD

7.36e-05317329882504
Pubmed

Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition.

MMP2 DMD

7.36e-053173228992079
Pubmed

Matrix metalloproteinase gene polymorphisms and bronchopulmonary dysplasia: identification of MMP16 as a new player in lung development.

MMP2 MMP16

7.36e-053173218784838
Pubmed

Two-dimensional gel electrophoresis, protein electroblotting and microsequencing: a direct link between proteins and genes.

RBBP4 P4HB

7.36e-05317321699755
Pubmed

Age-related changes in collagen gene expression in the muscles of mdx dystrophic and normal mice.

DMD COL1A1

7.36e-05317327919967
Pubmed

Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1.

ACADS HPD

7.36e-05317322263635
Pubmed

Matrix metalloproteinase-2 inducing COL1A1 synthesis via integrin alpha Ⅴ promotes invasion and metastasis of cholangiocarcinoma cells.

MMP2 COL1A1

7.36e-053173238123132
Pubmed

LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β-catenin signaling pathway.

CAPRIN2 EP300

7.36e-053173232691935
Pubmed

Screening of MYH7, MYBPC3, and TNNT2 genes in Brazilian patients with hypertrophic cardiomyopathy.

MYH7 MYBPC1

7.36e-053173224093860
Pubmed

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.

RYR2 DMD

7.36e-053173220080623
Pubmed

Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

ZWILCH ZW10

7.36e-053173212686595
Pubmed

Acute inflammation plays a limited role in the regulation of adipose tissue COL1A1 protein abundance.

MMP2 COL1A1

7.36e-053173221775118
Pubmed

Matrix metalloproteinases mediate the dismantling of mesenchymal structures in the tadpole tail during thyroid hormone-induced tail resorption.

MMP2 MMP16

7.36e-053173211891989
Pubmed

Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex.

ZWILCH ZW10

7.36e-053173225849506
Pubmed

The C-terminal IgI domains of myosin-binding proteins C and H (MyBP-C and MyBP-H) are both necessary and sufficient for the intracellular crosslinking of sarcomeric myosin in transfected non-muscle cells.

MYBPC1 MYBPC2

7.36e-053173212154082
Pubmed

HP1a/KDM4A is involved in the autoregulatory loop of the oncogene gene c-Jun.

CBX5 KDM4A

7.36e-053173225945750
Pubmed

Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.

DNAH14 DNAH6

7.36e-053173229323929
Pubmed

ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei.

ATR CDK1

7.36e-053173237788673
Pubmed

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.

RBBP4 RBBP7

7.36e-053173227144666
Pubmed

Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.

RBBP4 RBBP7 CBX5

7.81e-0517173323281010
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ABCC1 ATR RBBP4 RBBP7 NSD2 EXOSC3 NOL11 BCOR LIN9 ZBTB7A POLR3E CBX5 NFRKB PTRH2 CDYL TOP1 EP300 ZC3HAV1

8.65e-0512941731830804502
GeneFamilyDyneins, axonemal

DNAH14 DNAH12 DNAH6 DNAH9 DNAH11

4.86e-08171125536
GeneFamilyFibronectin type III domain containing

OBSCN ANOS1 PTPRB PTPRQ MYBPC1 MYBPC2

4.83e-041601126555
GeneFamilyLysine methyltransferases|Myb/SANT domain containing|Polycomb repressive complex 2

RBBP4 RBBP7

5.61e-04611221347
GeneFamilyTopoisomerases

TOP3B TOP1

5.61e-04611221050
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC1 MYBPC2

1.04e-0381122658
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

1.33e-03911221306
GeneFamilyKelch like|BTB domain containing

KLHL10 KLHL30 KLHL34

2.23e-03421123617
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

2.41e-031211221243
GeneFamilyPHD finger proteins|NuRD complex

RBBP4 RBBP7

2.41e-031211221305
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D8B GRAMD1B

2.84e-031311221146
GeneFamilyC-type lectin domain family

CLEC18A CLEC18B CLEC18C

3.08e-03471123494
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD1 EPB41L5 PTPN3

3.67e-035011231293
GeneFamilyMyosin heavy chains

MYH7 MYH7B

3.79e-031511221098
GeneFamilyX-linked mental retardation|Angiotensin receptors

BRWD3 ZDHHC15 DMD

4.33e-03531123103
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF5 BRWD1

5.45e-03181122498
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD EP300

5.45e-0318112291
GeneFamilyWD repeat domain containing

RBBP4 RBBP7 DCAF5 BRWD3 CFAP57 BRWD1

5.83e-032621126362
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRB PTPRQ

7.40e-03211122813
GeneFamilyProtein disulfide isomerases

P4HB PDILT

7.40e-03211122692
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP2 MMP16

9.60e-03241122891
GeneFamilyPhosphodiesterases

PDE6A PDE8B

9.60e-03241122681
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL10 ZBTB7A KLHL30 KLHL34

9.68e-031341124861
CoexpressionHOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP6 ATR VPS13C RCVRN EPB41L5 OAS2 GRAMD1B MSRB2 GBP4 MED12L NUB1 APOBEC3C TAP1 ZC3HAV1

3.95e-0739417314M40996
CoexpressionGSE10325_BCELL_VS_MYELOID_UP

EVL KLHDC2 BCL7A POLR3E CBX5 FAM3C MAPK13 TOP3B TCTN1

6.83e-061971739M3081
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 MCAM HPSE2 RYR2 EGFL6 MYOF FAT1 ATRNL1 RIMS1 DMD COL1A1

2.38e-10189174117ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 MCAM HPSE2 VAT1L RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

2.66e-101911741108042952431ca1a6fd7dfc13f36eb28643979598
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 MCAM HPSE2 RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

4.43e-09191174107853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 MCAM HPSE2 RYR2 EGFL6 FAT1 ATRNL1 DMD COL1A1

6.93e-081921749992d08092edbc68c47b945deb8708379738c239a
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 RYR2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

9.82e-082001749c5e051f1aac8dda376c342a9932785a23450e073
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 RYR2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

9.82e-0820017499d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 RYR2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

9.82e-0820017498988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

9.82e-08200174967dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 FRMPD1 HPSE2 ABCA7 ATRNL1 DMD TCTN1

5.58e-07123174787401764a073c1808f214642a9c84299c78f7ec7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 FAT1 TRPM3 PTPRQ DMD DNAH9 DNAH11

6.67e-0718417482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 FAT1 TRPM3 PTPRQ DMD DNAH9 DNAH11

6.67e-0718417482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 FAT1 TRPM3 PTPRQ DMD DNAH9 DNAH11

6.67e-071841748ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCAM VAT1L RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD

6.67e-071841748327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCAM STYXL2 RYR2 EGFL6 MFAP3L FAT1 DMD COL1A1

7.24e-0718617484780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 HPSE2 VAT1L IQCA1L TRPM3 ACSBG2 RIMS1

1.16e-0613717474dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 HPSE2 VAT1L IQCA1L TRPM3 ACSBG2 RIMS1

1.16e-061371747c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

1.20e-061991748e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

1.25e-062001748f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

1.25e-062001748593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 MYOF FAT1 ATRNL1 MMP2 DMD COL1A1

1.25e-06200174887827041663013f5e7273168dc8709d69840e7ce
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

HPSE2 RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

1.25e-0620017485ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

HPSE2 RYR2 EGFL6 MYOF FAT1 ATRNL1 DMD COL1A1

1.25e-0620017488bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HPSE2 EGFL6 MYOF FAT1 PDE8B ATRNL1 DMD COL1A1

1.25e-06200174877631c471cc5d453a749784f838cfa6408caf09b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCAM RYR2 EGFL6 FAT1 ATRNL1 MED12L DMD

2.75e-0615617476365b69ede98bc866e996bc52736b00401aacf6f
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

KLHL10 PDE6A HPSE2 RYR2 SEL1L2 DMD DNAH9

3.68e-06163174719c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DCDC1 DNAH12 STPG1 ADGRF1 DNAH6 DNAH9 DNAH11

4.31e-06167174726cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DCDC1 RAD51AP2 DNAH12 PDILT CFAP57 DNAH6 DNAH11

4.49e-0616817479a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH12 MKX CFAP57 DNAH6 DNAH9 DNAH11

4.67e-061691747fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 VPS13C TUT7 PTPRB GBP4 TAP1 ZC3HAV1

6.56e-06178174701dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

PRUNE2 MCAM HPSE2 RYR2 DMD MMP16 COL1A1

7.06e-061801747d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ZWILCH NSD2 ACTR3B TRPM3 MKX CDK1

7.06e-06180174743fd5c498a87bb078d101298b472656f3294686a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FTCD BCOR RYR2 SLC12A1 TRPM3 HPD PTPRQ

7.32e-061811747c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 FTCD MFAP3L PTPN3 SLC12A1 TRPM3 SCIN

7.58e-0618217479d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

7.58e-0618217477ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL3 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 JHY

8.14e-061841747797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

8.14e-0618417475daff849625f2f41d56615569c0ed59cd733b34c
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL3 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 JHY

8.14e-06184174777d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 HPSE2 FAT1 ATRNL1 RIMS1 DMD COL1A1

8.44e-061851747e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

8.44e-06185174730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 HPSE2 RYR2 MYOF ATRNL1 DMD COL1A1

9.37e-0618817473177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 HPSE2 RYR2 ATRNL1 RIMS1 DMD COL1A1

9.37e-061881747293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL3 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

9.70e-06189174702c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL3 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

9.70e-061891747164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCAM VAT1L RYR2 EGFL6 FAT1 DMD COL1A1

9.70e-061891747975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL3 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3 DNAH11

9.70e-061891747a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 HPSE2 VAT1L ANOS1 FAT1 CSK IL1RAP

1.07e-05192174763d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 EPB41L5 DNAH14 PTPN3 FAT1 SLC12A1 TRPM3

1.15e-05194174793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

OAS2 ALPK1 GBP4 FCGR2A NUB1 TAP1 ZC3HAV1

1.15e-051941747267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GBP6 DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 DNAH11

1.15e-051941747756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.19e-0519517473486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.19e-051951747e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.23e-05196174727b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.23e-051961747d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.27e-0519717476865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.27e-05197174771fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH12 CFAP57 DMD DNAH6 DNAH9 DNAH11

1.27e-05197174774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.27e-051971747e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.27e-051971747d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 TCTN1 DNAH11

1.31e-051981747ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

OBSCN MCAM RYR2 EGFL6 FAT1 PDE8B DMD

1.40e-0520017470c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OBSCN MCAM RYR2 EGFL6 FAT1 PDE8B DMD

1.40e-052001747522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellVE|World / Condition, Cell_class and T cell subcluster

VPS13C OAS2 GBP4 CSK NUB1 TAP1 TOP1

1.40e-0520017478ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

OBSCN MCAM RYR2 EGFL6 FAT1 PDE8B DMD

1.40e-05200174794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 MYOF FAT1 ATRNL1 DMD COL1A1

1.40e-052001747c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 FAT1 ATRNL1 MMP2 DMD COL1A1

1.40e-05200174708bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 FAT1 ATRNL1 MMP2 DMD COL1A1

1.40e-05200174702cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 HPSE2 FAT1 ATRNL1 MMP2 DMD COL1A1

1.40e-052001747dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

DCDC1 DNAH12 TRPM3 DNAH6 DNAH9 JHY DNAH11

1.40e-052001747177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUT7 BMX PTPRB SLC12A1 ADGRF1 TRPV5

2.03e-051421746191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TUT7 BMX PTPRB SLC12A1 ADGRF1 TRPV5

2.11e-051431746b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

GBP6 DCDC1 ZNF20 DNAH12 DNAH6 DNAH9

2.87e-0515117469d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RBBP7 FRMPD1 PTPN3 SEL1L2 UQCR11 TRPV5

3.09e-05153174679c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

HPSE2 RYR2 SEL1L2 RIMS1 DMD DNAH9

3.84e-0515917465335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY8 RYR2 SLC12A1 PTPRQ MKX DNAH9

3.98e-051601746c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY8 RYR2 SLC12A1 PTPRQ MKX DNAH9

3.98e-05160174625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

PRUNE2 MCAM HPSE2 RYR2 ACSBG2 DMD

4.12e-05161174664891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLEC18A OAS2 GBP4 MED12L TAP1 ZC3HAV1

4.41e-051631746d005115aa1e1458b51de7eb719794617a4168608
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ATOH7 VAT1L MFAP3L ANOS1 RIMS1 SCIN

5.22e-051681746e870d2e69316406f45112ed0bf324b24f902a99e
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRMPD1 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3

5.22e-051681746fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 DNAH14 MKX CDK1 DNAH6 MYBPC1

5.22e-051681746bfa1491e8d433933003778b274710d3a16d973cb
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ATOH7 VAT1L MFAP3L ANOS1 RIMS1 SCIN

5.22e-051681746403aba73a0f9ffb32252288d075fad8a588ca440
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRMPD1 DNAH12 CFAP57 DNAH6 DNAH9 ODAD3

5.22e-0516817467edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 DNAH11

5.39e-05169174614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OBSCN HPSE2 RYR2 KLHL30 RIMS1 MYBPC2

5.57e-051701746cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OBSCN HPSE2 RYR2 KLHL30 RIMS1 MYBPC2

5.57e-051701746da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRUNE2 MCAM HPSE2 RYR2 DMD MMP16

6.14e-051731746cb6389536195443633adb06e5f1b7483530773d1
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 DNAH11

6.14e-051731746c3762655caa79ac4879876f470d32578a3c93b01
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C CHD9 RYR2 CBX5 DMD ARHGAP21

6.75e-051761746749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 TTLL3 CFAP57 DNAH6 DNAH9 DNAH11

6.75e-051761746ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 ALPK1 KLHL30 CAPRIN2 DNAH9 DNAH11

6.97e-051771746e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DCDC1 DNAH12 DNAH6 DNAH9 ODAD3 DNAH11

7.19e-051781746de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A FTCD ADCY8 ACSBG2 CFAP57 JHY

7.19e-051781746b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A FTCD ADCY8 ACSBG2 CFAP57 JHY

7.19e-05178174658857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC18A FTCD ADCY8 ACSBG2 CFAP57 JHY

7.19e-0517817468b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DNAH12 CFAP57 DNAH6 DNAH9 DNAH11

7.19e-0517817463b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 EPB41L5 MYOF ANOS1 TRPM3 PTPRQ

7.41e-05179174604ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MACC1 FTCD ADCY8 FAT1 TRPM3

7.41e-05179174658ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ATRNL1 RIMS1 MMP2 DMD COL1A1

7.41e-05179174602c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRUNE2 ABCC1 MYH7B RYR2 TRPM3 CFAP57

7.41e-05179174614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellVE-mono2-|VE / Condition, Cell_class and T cell subcluster

SLC12A1 FCGR2A MKX SEL1L2 MMP2 SCIN

7.64e-051801746188e7c65e9a86771f89029b18dfb3216b2c9d7d7
DrugBenzydamine hydrochloride [132-69-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

NUDT2 ALPK1 MSRB2 MYOF HNRNPUL2 PDE8B MMP16 JHY COL1A1 BRWD1

2.27e-06197169105811_DN
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH7 MYH7B MYBPC1

7.57e-05151663DOID:0050646 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13B

9.40e-0531662DOID:0111590 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH7 MYH7B MTMR1 MYBPC2

1.55e-04481664DOID:423 (implicated_via_orthology)
Diseasefat body mass

PRUNE2 DOK2 ACTR3B ADCY8 MKX MED12L NUB1

2.38e-042171667EFO_0005409
Diseasemagnesium measurement

DCDC1 ALPK1 ADCY8 CANT1

5.31e-04661664EFO_0004845
Diseasecardiomyopathy (is_marker_for)

MMP2 EP300

6.49e-0471662DOID:0050700 (is_marker_for)
Diseasebehavioural disinhibition measurement

SEL1L2 MMP2 DNAH9 DNAH11

8.61e-04751664EFO_0006946
DiseaseEmbryonal Rhabdomyosarcoma

BCOR DMD

8.61e-0481662C0206656
DiseaseMalignant neoplasm of breast

EVL ABCC1 NSD2 UBR4 FRMPD1 NUDT2 OBSCN STPG1 WBP4 MMP2 DMD DNAH9 TOP1 EP300 VPS13B

1.13e-03107416615C0006142
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

1.37e-03101662DOID:0080326 (implicated_via_orthology)
Diseasedilated cardiomyopathy (is_marker_for)

OBSCN MMP2 DMD

1.38e-03391663DOID:12930 (is_marker_for)
Diseasered blood cell density measurement

DCDC1 ATR ACADS EPB41L5 BCL7A ZBTB7A PTPN3 TRPM3 KLHL30 PDE8B KDM4A TOP1 VPS13B

1.48e-0388016613EFO_0007978
DiseaseNephrosclerosis

ALPK1 COL1A1

1.67e-03111662C0027719
Diseasediffuse scleroderma (is_implicated_in)

FCGR2A TAP1

1.67e-03111662DOID:1580 (is_implicated_in)
DiseaseTumoral calcinosis

MMP2 DMD COL1A1

1.71e-03421663C0263628
DiseaseCalcinosis

MMP2 DMD COL1A1

1.71e-03421663C0006663
DiseaseMicrocalcification

MMP2 DMD COL1A1

1.71e-03421663C0521174
Diseasedistal myopathy (implicated_via_orthology)

MYH7 MYH7B

2.00e-03121662DOID:11720 (implicated_via_orthology)
DiseaseAL amyloidosis

GRAMD1B DNAH11

2.00e-03121662MONDO_0019438
Diseasemyotonia congenita (implicated_via_orthology)

MYH7 MYH7B

2.00e-03121662DOID:2106 (implicated_via_orthology)
DiseaseColorectal Carcinoma

EVL ABCC1 TTLL3 OBSCN ADCY8 FAT1 CBX5 PDILT MMP2 DMD EP300

2.17e-0370216611C0009402
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

ACTR3B MMP16 VPS13B

2.22e-03461663EFO_0005325, HP_0012735
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH7 MYH7B

2.36e-03131662DOID:397 (implicated_via_orthology)
DiseaseOsteogenesis Imperfecta

P4HB COL1A1

2.36e-03131662C0029434
DiseaseOsteosarcoma

BCOR MMP2 ZW10

2.36e-03471663C0029463
DiseasePrimary Ciliary Dyskinesia

DNAH9 ODAD3 DNAH11

2.36e-03471663C4551720
Diseaseresponse to antineoplastic agent

UBR4 ADCY8 RYR2 COL1A1

2.40e-03991664GO_0097327
DiseaseDisease Exacerbation

ABCC1 ABCA7 MMP2 IL1RAP TOP1

2.47e-031651665C0235874
Diseaseocular hypertension, response to triamcinolone acetonide

TTLL3 TUT7 CHD9

2.66e-03491663EFO_0006954, EFO_1001069
DiseaseKartagener syndrome (implicated_via_orthology)

ODAD3 DNAH11

2.74e-03141662DOID:0050144 (implicated_via_orthology)
DiseaseLeft ventricular noncompaction

MYH7 MYH7B

2.74e-03141662C1960469
Diseaseamenorrhea, response to antineoplastic agent

ADCY8 RIMS1

3.15e-03151662EFO_0010269, GO_0097327
Diseasetemporal arteritis (is_implicated_in)

FCGR2A MMP2

3.58e-03161662DOID:13375 (is_implicated_in)
DiseaseGlioblastoma Multiforme

AKT3 ZBTB7A FAT1 MMP2

3.63e-031111664C1621958
DiseaseMuscle hypotonia

NSD2 NUDT2

4.05e-03171662C0026827
DiseaseHypertrophic Cardiomyopathy

MYH7 OBSCN RYR2

4.10e-03571663C0007194
Diseasesyndrome (implicated_via_orthology)

NSD2 ZDHHC15

4.54e-03181662DOID:225 (implicated_via_orthology)
DiseaseOral Submucous Fibrosis

MMP2 COL1A1

4.54e-03181662C0029172
Diseasecolorectal cancer (is_implicated_in)

BCOR YTHDF1 FAT1 EP300

4.93e-031211664DOID:9256 (is_implicated_in)
DiseaseColorectal Neoplasms

EVL ABCC1 FAT1 CBX5 MMP2 EP300

4.93e-032771666C0009404
Diseaserenal system measurement

DCDC1 PDILT

5.59e-03201662EFO_0004742
DiseaseFetal Growth Retardation

NSD2 MMP2

5.59e-03201662C0015934

Protein segments in the cluster

PeptideGeneStartEntry
TYPALASKNGKKWEI

ACSBG2

66

Q5FVE4
IGAKKPQYDIWGKTV

ADCY8

1101

P40145
YDKKQQQEILAAKPW

COPS5

31

Q92905
TIKRKLDTGQYQEPW

EP300

1101

Q09472
WEKQKEQPKEYQRIL

ATG4A

101

Q8WYN0
SEDEKWKTGKIQLYQ

EGFL6

496

Q8IUX8
VKGQVEYLLKWKGFS

CBX5

31

P45973
PILKFGSKEQKQAWV

ACADS

126

P16219
KPLYSWEEAKQKTVE

HSD3B1

341

P14060
RKFIDWKGIPVNKSQ

ADGRF1

426

Q5T601
VQLGKWKGQYDVAVK

BMX

431

P51813
DVDPRKWIKQYTGIN

ACTR3B

246

Q9P1U1
PKWRATYEDQQIKKI

FAM47DP

251

A6NHR8
WKDKPLVKVTFFQNG

FCGR2A

146

P12318
VYNDNEPFKPWKGLK

APOBEC3C

161

Q9NRW3
IDPQQQGIKWIKNKY

DNAH11

3496

Q96DT5
RKSKIYSVNLQKQPW

BRWD3

961

Q6RI45
ADPNKKWVQKYISDL

CCL18

71

P55774
VTKDPNWYKAKNKVG

CSK

41

P41240
NWYKAKNKVGREGII

CSK

46

P41240
WKEGPYTVDAIQKKI

DMD

2606

P11532
NKPKTVIYWLAEVKD

NUDT2

86

P50583
WNQGKTVVKSDKLVY

BCOR

791

Q6W2J9
SWVKNLAQYGKPIKN

GKN3P

121

P0CG01
KQPWGLVKTFIEKNF

GRAMD1B

506

Q3KR37
QGLKTKKWVNEVRYG

ABCA7

1401

Q8IZY2
SGVNWQDVYDKKLVP

AKT3

406

Q9Y243
WQYKQAVGPEDKTNL

ALPK1

66

Q96QP1
KPKWDKNQITYRIIG

MMP2

116

P08253
YKRQGLPNESWKISK

MTMR1

236

Q13613
IYWSQNRPDVKKQKL

RAD51AP2

296

Q09MP3
ILDWVPYINGKFKKD

UQCR11

41

O14957
KLELTAKQYPDIWNK

RIC1

291

Q4ADV7
AKQYPDIWNKTGAVK

RIC1

296

Q4ADV7
NKVKIQPVAKYDWEQ

EDC4

116

Q6P2E9
KKLLPQEKNVLSQYW

PTPN3

311

P26045
VDYNIIGWLQKNKDP

MYH7

586

P12883
KKVYVYDPGANLWQK

KLHL30

481

Q0D2K2
QLWKPPYTDENKKVG

NUB1

21

Q9Y5A7
YKVSDQKPLGSWSVK

NOL11

46

Q9H8H0
VESGQIYKNPVTWLK

ANKRD31

1736

Q8N7Z5
TIQNEWKVYVKKPLD

FAT1

2971

Q14517
KNNKDTNKYEGWPEV

FAM3C

201

Q92520
LQVKVYWKKTEDPTV

ANOS1

441

P23352
PLSLKNEQKIWVSYG

DCDC1

566

M0R2J8
LILYNPNGTKKENWK

PTPRB

1206

P23467
KPDGVYIEEVLSKWK

OGFRL1

131

Q5TC84
WQPGTEYDNVVLKKG

DOK2

396

O60496
LYVLGPEEQVWSKKA

KLHL34

496

Q8N239
PQFKWYNSIGKLLKE

MFAP3L

76

O75121
EKYSSLQKTPVWKGR

LIN9

31

Q5TKA1
GIYQQKFLKEPSKTW

MAEL

251

Q96JY0
KKKPQVNAKDNYWLV

MED12L

91

Q86YW9
WPEEYNKALEGDKTK

MAGEE2

281

Q8TD90
LRYDPNWKSKKEEGQ

JHY

126

Q6NUN7
SPFVEFKEKTQQWKL

NFRKB

446

Q6P4R8
LENKIQDWYDKKGPA

KRT9

181

P35527
QDWYDKKGPAAIQKN

KRT9

186

P35527
LTVIKWKGEKSKYPQ

IL1RAP

521

Q9NPH3
DQKIISYLWEKTQGP

KIAA0319L

626

Q8IZA0
YNVDQKWQKFIPGSE

CFAP57

41

Q96MR6
AEWEEYKTGIKKAPI

CWF19L1

51

Q69YN2
VNENPEWVKVVGYKG

CANT1

241

Q8WVQ1
VVPYSIVGWLEKNKD

MYH7B

631

A7E2Y1
LDTWYVIKPGNTKEK

FBXO46

86

Q6PJ61
KGPSKDDTYWKEINA

MKX

296

Q8IYA7
TEQYKWLEIKEGKLG

KIAA1586

146

Q9HCI6
QKILKTREVYGKEPW

PDE6A

466

P16499
INTCIKKGKEWQGVY

PDE8B

331

O95263
YDDTSKKWVPIKPGQ

EVL

16

Q9UI08
QYPETKIIKTDGKGW

NSD2

1061

O96028
TQWALKYAKENPEKR

HNRNPUL2

466

Q1KMD3
SGVEKIIKIWSPYKQ

DCAF5

351

Q96JK2
NTWYPKVINLFTKKE

DNAH12

261

Q6ZR08
PERYKLWKAGKDNTV

KDM4A

326

O75164
KQDVNKTAWELPKTY

MAPK13

11

O15264
QEGKLYWGDAKTDKI

LRP5L

131

A4QPB2
QVEWDYKLVPRKGVK

GBP4

456

Q96PP9
YWQVPRKGVKAKEVF

GBP6

446

Q6ZN66
IIKEWAAYKGKSPQT

FAM120A

641

Q9NZB2
KQLAPIWDKLGETYK

P4HB

401

P07237
TIKNVEPKQELKVWY

PRDM10

311

Q9NQV6
KVVNTYTPGKKIWLE

HPSE2

366

Q8WWQ2
VPAQKLGWFIQEYLK

OAS2

11

P29728
VINEEYKIWKKNTPF

RBBP4

16

Q09028
INEEYKIWKKNTPFL

RBBP7

16

Q16576
KWDPPKKANGIITQY

PTPRQ

1401

Q9UMZ3
KIEKAYGQQLTDWAK

PACSIN1

51

Q9BY11
VLPGQLSVKLWYDKV

RIMS1

741

Q86UR5
VKKILEPKWNQTFVY

RIMS1

801

Q86UR5
QAQTEVTWYKDGKKL

OBSCN

916

Q5VST9
AQPQTEVTWYKDGKK

OBSCN

1191

Q5VST9
QAQTEVTWYKDGKKL

OBSCN

1376

Q5VST9
PKPVISWYKDGKAVQ

OBSCN

6041

Q5VST9
GSVDFKKNWIQYKEG

FGG

226

P02679
QKSTDWSGVKKPIYL

ATR

1466

Q13535
PSNIWKKIDQSRDYK

CHD9

841

Q3L8U1
IFEKWKEYRGQTPAQ

EPB41L5

201

Q9HCM4
YLGPLKTRVDEWQKQ

DNAH6

1076

Q9C0G6
VSPAYLKKWSAKGIQ

GDE1

281

Q9NZC3
GWNNTEKKVYNIPGI

KLHL10

71

Q6JEL2
KKNWQYEGPTQKLFL

CDYL

16

Q9Y232
AQPQKISLKYIEKDW

FRMPD1

321

Q5SYB0
KDYWQKQPQLKLKET

C3orf38

96

Q5JPI3
VILKEWSAYKGKSPQ

FAM120C

691

Q9NX05
WAQNELDQKKVKYPK

GID8

201

Q9NWU2
VVPQWGQDKKLSKYE

ATOH7

66

Q8N100
KYTQQKVSPWVGLRK

ATRNL1

801

Q5VV63
EKLLYKPQAGEWGQK

BRWD1

1146

Q9NSI6
QWKQDTPKSKAGYVQ

CAPRIN2

471

Q6IMN6
WYPEKNPDKLTKIIQ

DNAH14

1751

Q0VDD8
VKAIGQSKVKEWYVG

MACC1

586

Q6ZN28
QSKVKEWYVGVLRGK

MACC1

591

Q6ZN28
PPSSKDKLGVWVYKN

KLHDC2

141

Q9Y2U9
KIQVPEEQKDEKYWS

DBP

246

Q10586
VDPQLQGIKWIKNKY

DNAH9

3466

Q9NYC9
YKWVPVTEPKVDDKN

BCL7A

46

Q4VC05
PESAFWKKIIAYQQK

RYR2

4476

Q92736
VQGNWVVKSDILYPK

POLR3E

321

Q9NVU0
WVDSQQKRYVPVKGD

EXOSC3

101

Q9NQT5
LKKVQGIGWYLDEKN

FTCD

216

O95954
QVIWYKNGRPLKEEK

MCAM

171

P43121
QKEWNPSLFKVLYKT

ABCC1

306

P33527
PKYWDQGLVKQLVGK

PDILT

381

Q8N807
PWVEQDKFGKVKFAV

HPD

121

P32754
VKVPKYLSQQWAKAS

GTF2F2

21

P13984
GLYKEGQNWLEKKDV

SEC11C

136

Q9BY50
PKTRGKVYEKVDSWN

PRUNE2

906

Q8WUY3
KQIFVWKGKDANPQE

SCIN

291

Q9Y6U3
NTPEKRAEKIWKYFG

RCVRN

146

P35243
KYFQKAAEKGWPDAQ

SEL1L2

396

Q5TEA6
WIGNAEKNFYKKTPK

IQCA1L

626

A6NCM1
KWEKPYLKNRTGQAL

ODAD3

136

A5D8V7
SQVEKGSYPWQVSLK

OVCH2

56

Q7RTZ1
KTLTNKWYEEVRQGP

SLC9A8

556

Q9Y2E8
YKKNWRKAPLTEIEN

SLC12A1

781

Q13621
LPKKVGKWYQLLEVQ

TAP1

341

Q03518
NKVEVQYKTLPGWNT

ADSS2

396

P30520
TWKSEPGQVKAAVKY

AKR1A1

21

P14550
VESLQDYKNTFPKWK

CDK1

231

P06493
GVKKRKWIYDEPQNF

C12orf50

286

Q8NA57
GNWEVNGKTIVPYKK

CLEC18A

186

A5D8T8
GNWEVNGKTIIPYKK

CLEC18B

186

Q6UXF7
GNWEVNGKTIVPYKK

CLEC18C

186

Q8NCF0
SVAQKNWYISKNPKD

COL1A1

1306

P02452
KQWEYCGQPKVVVKA

PTRH2

106

Q9Y3E5
FLGKYNKWDKVDPAE

TOP3B

66

O95985
PTGKWQLKVSNDGYK

VWDE

1011

Q8N2E2
EKPQKWRVEIYSGQK

ZWILCH

526

Q9H900
VGKTWKVQNIEDEYK

ZNF20

46

P17024
KKVPKGTSSYQAEWI

TSR1

391

Q2NL82
RPKKWSVVNFLGKEY

ZSCAN5DP

121

P0CG00
EYWKFNNQILKVEPG

MMP16

506

P51512
KSEWQKKLTPEQFYV

MSRB2

51

Q9Y3D2
WNTVERLKDNKPNYK

PES1

101

O00541
KGKGKIDIQAYLSQW

TBC1D8B

956

Q0IIM8
KPDLYKESWKNNPAI

TTI2

211

Q6NXR4
LPGKQSFLYNEDKKW

STPG1

316

Q5TH74
PGKLLQKVKVWLQEY

TRPM3

951

Q9HCF6
EEEKLYEQWKKGQGL

STYXL2

346

Q5VZP5
YEQWKKGQGLLSDKV

STYXL2

351

Q5VZP5
VKWTKYGSLLNPQAK

TCTN1

511

Q2MV58
KTLKKSNPYGEWQEI

WBP4

286

O75554
TLKIPWKNLYGEAVV

VPS13C

66

Q709C8
KLVVKSEWKSYPIQA

TTLL3

156

Q9Y4R7
LYNQKKIKPVVDSLW

VAT1L

341

Q9HCJ6
KSLQPIWPYNKKDSD

VPS13B

2941

Q7Z7G8
GTWIQYGEEKDKRKN

ZC3HAV1

616

Q7Z2W4
YKGEKKPEIFVDGWN

TUT7

1196

Q5VYS8
KIYGKTKEQFGWPDE

UBR4

2421

Q5T4S7
PDSNGEKKQTYKWSG

ARHGAP21

516

Q5T5U3
IGKKWKPQNIYVEYE

ZNF433

46

Q8N7K0
PSSRIKGEKDWQKYE

TOP1

431

P11387
IQIKKFTFGLDWVPK

USP5

571

P45974
DGDVYPAWSQKVEKK

ZBTB7A

361

O95365
TPVKELVSFKWNKYG

TRPV5

311

Q9NQA5
KGKFDVQWIFVKDVP

YTHDF1

471

Q9BYJ9
QQVFGDKKKFWLIPI

ZDHHC15

271

Q96MV8
NKKYQEEVPVYVPKW

ZW10

706

O43264
KYTWNDVGQLVEKLK

AGL

191

P35573
YVKGWIPGNEENKQK

MYOF

1816

Q9NZM1
LADPKLEVKWYKNGQ

MYBPC1

276

Q00872
LEVKWYKNGQEIRPS

MYBPC1

281

Q00872
KVTGKWYKNGVEVRP

MYBPC2

466

Q14324