Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	valine-tRNA ligase activity	VARS2 VARS1	1.88e-05	2	87	2	GO:0004832
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXB4 ZBTB45 MYPOP HOXC4 OVOL1 GCM2 HOXD1 NEUROD4 GLI1 WT1 IRF4 KDM6B KLF4 HOXB13 TBX1	2.88e-04	1244	87	15	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXB4 ZBTB45 MYPOP HOXC4 KMT2D OVOL1 GCM2 HOXD1 NEUROD4 GLI1 NFX1 WT1 IRF4 KLF4 HOXB13 TBX1	3.54e-04	1412	87	16	GO:0000981
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXB4 ZBTB45 MYPOP HOXC4 OVOL1 GCM2 HOXD1 NEUROD4 GLI1 WT1 IRF4 KDM6B KLF4 HOXB13 TBX1	3.62e-04	1271	87	15	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXB4 ZBTB45 MYPOP HOXC4 OVOL1 GCM2 HOXD1 NEUROD4 GLI1 NFX1 WT1 IRF4 KDM6B KLF4 HOXB13 TBX1	5.09e-04	1459	87	16	GO:0000977
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2D	5.17e-04	8	87	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2D	8.26e-04	10	87	2	GO:0140999
GeneOntologyBiologicalProcess	valyl-tRNA aminoacylation	VARS2 VARS1	1.68e-05	2	85	2	GO:0006438
GeneOntologyCellularComponent	MLL3/4 complex	KMT2C KMT2D KDM6B	1.49e-05	12	87	3	GO:0044666
Domain	Valyl-tRNA_ligase	VARS2 VARS1	2.10e-05	2	86	2	IPR002303
Domain	Anticodon_Ia_Val	VARS2 VARS1	2.10e-05	2	86	2	IPR033705
Domain	Homeobox_Antennapedia_CS	HOXB4 HOXC4 HOXD1	1.18e-04	21	86	3	IPR001827
Domain	ANTENNAPEDIA	HOXB4 HOXC4 HOXD1	1.78e-04	24	86	3	PS00032
Domain	FYrich_C	KMT2C KMT2D	2.08e-04	5	86	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	2.08e-04	5	86	2	IPR003888
Domain	FYRC	KMT2C KMT2D	2.08e-04	5	86	2	SM00542
Domain	FYRN	KMT2C KMT2D	2.08e-04	5	86	2	SM00541
Domain	FYRN	KMT2C KMT2D	2.08e-04	5	86	2	PF05964
Domain	FYRC	KMT2C KMT2D	2.08e-04	5	86	2	PF05965
Domain	FYRC	KMT2C KMT2D	2.08e-04	5	86	2	PS51543
Domain	FYRN	KMT2C KMT2D	2.08e-04	5	86	2	PS51542
Domain	Val/Leu/Ile-tRNA-synth_edit	VARS2 VARS1	3.11e-04	6	86	2	IPR009008
Domain	Anticodon_1	VARS2 VARS1	3.11e-04	6	86	2	PF08264
Domain	M/V/L/I-tRNA-synth_anticd-bd	VARS2 VARS1	3.11e-04	6	86	2	IPR013155
Domain	-	VARS2 VARS1	3.11e-04	6	86	2	3.90.740.10
Domain	aa-tRNA-synth_Ia	VARS2 VARS1	4.34e-04	7	86	2	IPR002300
Domain	tRNA-synt_1	VARS2 VARS1	4.34e-04	7	86	2	PF00133
Domain	EGF_CA	TPO THBS3 FAT3 LRP1	6.68e-04	86	86	4	PF07645
Domain	EGF_Ca-bd_CS	TPO THBS3 FAT3 LRP1	1.05e-03	97	86	4	IPR018097
Domain	-	VARS2 VARS1	1.12e-03	11	86	2	1.10.730.10
Domain	EGF_CA	TPO THBS3 FAT3 LRP1	1.13e-03	99	86	4	PS01187
Domain	Homeobox_antennapedia	HOXB4 HOXC4	1.34e-03	12	86	2	IPR017995
Domain	SMAD_FHA_domain	AFDN IRF4 SMAD6	1.77e-03	52	86	3	IPR008984
Domain	HMG_box	KMT2C KMT2D TOX	1.87e-03	53	86	3	PF00505
Domain	HMG	KMT2C KMT2D TOX	1.97e-03	54	86	3	SM00398
Domain	tRNAsynth_Ia_anticodon-bd	VARS2 VARS1	2.12e-03	15	86	2	IPR009080
Domain	Post-SET_dom	KMT2C KMT2D	2.41e-03	16	86	2	IPR003616
Domain	PostSET	KMT2C KMT2D	2.41e-03	16	86	2	SM00508
Domain	SMAD_dom-like	IRF4 SMAD6	2.41e-03	16	86	2	IPR017855
Domain	AT_hook	PRR12 KMT2C	2.41e-03	16	86	2	PF02178
Domain	-	IRF4 SMAD6	2.41e-03	16	86	2	2.60.200.10
Domain	POST_SET	KMT2C KMT2D	2.41e-03	16	86	2	PS50868
Domain	EGF_CA	TPO THBS3 FAT3 LRP1	2.44e-03	122	86	4	SM00179
Domain	EGF-like_Ca-bd_dom	TPO THBS3 FAT3 LRP1	2.58e-03	124	86	4	IPR001881
Domain	aa-tRNA-synth_I_CS	VARS2 VARS1	3.06e-03	18	86	2	IPR001412
Domain	HMG_box_dom	KMT2C KMT2D TOX	3.35e-03	65	86	3	IPR009071
Domain	AA_TRNA_LIGASE_I	VARS2 VARS1	3.41e-03	19	86	2	PS00178
Domain	CONNEXINS_2	GJA4 GJD3	3.77e-03	20	86	2	PS00408
Domain	Connexin	GJA4 GJD3	3.77e-03	20	86	2	IPR000500
Domain	Connexin_CCC	GJA4 GJD3	3.77e-03	20	86	2	IPR019570
Domain	Connexin_N	GJA4 GJD3	3.77e-03	20	86	2	IPR013092
Domain	Connexin	GJA4 GJD3	3.77e-03	20	86	2	PF00029
Domain	Connexin_CCC	GJA4 GJD3	3.77e-03	20	86	2	SM01089
Domain	Connexin_CS	GJA4 GJD3	3.77e-03	20	86	2	IPR017990
Domain	CNX	GJA4 GJD3	3.77e-03	20	86	2	SM00037
Domain	Ser-Thr/Tyr_kinase_cat_dom	TYK2 ROR1 PRKX EPHA7	3.79e-03	138	86	4	IPR001245
Domain	EPHD	KMT2C KMT2D	4.56e-03	22	86	2	PS51805
Domain	EGF	TPO THBS3 FAT3 PCSK6 LRP1	4.61e-03	235	86	5	SM00181
Domain	Frizzled_dom	ROR1 MFRP	5.42e-03	24	86	2	IPR020067
Domain	FZ	ROR1 MFRP	5.42e-03	24	86	2	PS50038
Domain	Fz	ROR1 MFRP	5.42e-03	24	86	2	PF01392
Domain	Znf_PHD-finger	KMT2C KMT2D NFX1	5.79e-03	79	86	3	IPR019787
Domain	Growth_fac_rcpt_	THBS3 PCSK6 LRP1 EPHA7	5.85e-03	156	86	4	IPR009030
Domain	EGF-like_dom	TPO THBS3 FAT3 PCSK6 LRP1	5.87e-03	249	86	5	IPR000742
Domain	AT_hook	PRR12 KMT2C	6.83e-03	27	86	2	SM00384
Domain	AT_hook_DNA-bd_motif	PRR12 KMT2C	6.83e-03	27	86	2	IPR017956
Domain	EGF-like_CS	TPO THBS3 FAT3 LRP1 EPHA7	7.13e-03	261	86	5	IPR013032
Domain	EGF_2	TPO THBS3 FAT3 LRP1 EPHA7	7.58e-03	265	86	5	PS01186
Domain	TyrKc	TYK2 ROR1 EPHA7	7.81e-03	88	86	3	SM00219
Domain	Tyr_kinase_cat_dom	TYK2 ROR1 EPHA7	7.81e-03	88	86	3	IPR020635
Domain	Homeobox_metazoa	HOXB4 HOXC4 HOXD1	8.30e-03	90	86	3	IPR020479
Domain	HMGI/Y_DNA-bd_CS	PRR12 KMT2C	8.94e-03	31	86	2	IPR000637
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TYK2 MPP3 CCDC71L PRR12 KMT2C HOXB4 KMT2D OVOL1 KIF26A GLI1 NFX1 MAPKBP1 KDM6B KLF4 FHIP1B DOCK6 TRIB1 ARHGAP21 HOXB13	4.11e-11	1105	89	19	35748872
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KMT2C THBS3 OVOL1 GCM2 TOX NEUROD4 GLI1 PCSK6 NFX1 WT1 AFDN KLF4 CRIP3 HOXB13 RNF111	3.57e-10	709	89	15	22988430
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXB4 MYPOP HOXC4 KMT2D GCM2 HOXD1 NEUROD4 GLI1 NFX1 WT1 IRF4 KLF4 HOXB13 TBX1	7.70e-08	908	89	14	19274049
Pubmed	New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.	HOXB4 HOXC4 HOXD1 KDM6B HOXB13	1.89e-07	50	89	5	28188179
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HOXB4 ZBTB45 HOXC4 OVOL1 GCM2 HOXD1 IRF4 KLF4 HOXB13 TBX1	1.36e-06	544	89	10	28473536
Pubmed	Quantification of Hox and surfactant protein-B transcription during murine lung development.	HOXB4 HOXC4 HOXD1 HOXB13	3.41e-06	40	89	4	19204410
Pubmed	Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.	HOXB4 HOXC4 HOXD1 HOXB13	3.77e-06	41	89	4	32479258
Pubmed	Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome.	HOXB4 GCM2 TBX1	4.55e-06	13	89	3	16399080
Pubmed	Reduction of Hox gene expression by histone H1 depletion.	HOXB4 HOXC4 HOXD1 HOXB13	4.58e-06	43	89	4	22701719
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	6.48e-06	2	89	2	28483418
Pubmed	JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency.	KDM6B KLF4	6.48e-06	2	89	2	33033262
Pubmed	Interferon Regulatory Factor 4 Inhibits Neointima Formation by Engaging Krüppel-Like Factor 4 Signaling.	IRF4 KLF4	6.48e-06	2	89	2	28851732
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	6.48e-06	2	89	2	34156443
Pubmed	Ovarian Tumor Domain-Containing 7B Attenuates Pathological Cardiac Hypertrophy by Inhibiting Ubiquitination and Degradation of Krüppel-Like Factor 4.	KLF4 OTUD7B	6.48e-06	2	89	2	38084712
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	6.48e-06	2	89	2	31924266
Pubmed	Jmjd3/IRF4 axis aggravates myeloid fibroblast activation and m2 macrophage to myofibroblast transition in renal fibrosis.	IRF4 KDM6B	6.48e-06	2	89	2	36159833
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	6.48e-06	2	89	2	27280393
Pubmed	Expression profile of orphan receptor tyrosine kinase (ROR1) and Wilms' tumor gene 1 (WT1) in different subsets of B-cell acute lymphoblastic leukemia.	ROR1 WT1	6.48e-06	2	89	2	18604725
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	6.48e-06	2	89	2	36869380
Pubmed	Arkadia enhances BMP signalling through ubiquitylation and degradation of Smad6.	RNF111 SMAD6	6.48e-06	2	89	2	25762727
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	6.48e-06	2	89	2	28967912
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	6.48e-06	2	89	2	25346535
Pubmed	HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4.	HOXB4 HOXC4	6.48e-06	2	89	2	22298821
Pubmed	The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection.	IRF4 KDM6B	6.48e-06	2	89	2	20729857
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	6.48e-06	2	89	2	36601880
Pubmed	HOXB13 homeodomain protein is cytoplasmic throughout fetal skin development.	HOXB4 HOXB13	6.48e-06	2	89	2	12761847
Pubmed	A distinct Hox code for the branchial region of the vertebrate head.	HOXB4 HOXC4 HOXD1	7.21e-06	15	89	3	1682814
Pubmed	Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries.	SEMA3D WT1 TBX1	7.21e-06	15	89	3	23797856
Pubmed	Epigenetic Modulation in Periodontitis: Interaction of Adiponectin and JMJD3-IRF4 Axis in Macrophages.	IRF4 KDM6B	1.94e-05	3	89	2	26399931
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	1.94e-05	3	89	2	23932714
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	1.94e-05	3	89	2	22183980
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	1.94e-05	3	89	2	21683083
Pubmed	Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.	HOXB4 HOXC4 KDM6B	2.08e-05	21	89	3	30254164
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2C KMT2D KDM6B	2.08e-05	21	89	3	27626377
Pubmed	Organization of human class I homeobox genes.	HOXB4 HOXC4 HOXD1	2.41e-05	22	89	3	2576652
Pubmed	Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.	HOXB4 HOXC4 HOXD1	2.76e-05	23	89	3	28041967
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	3.87e-05	4	89	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	3.87e-05	4	89	2	34645806
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	3.87e-05	4	89	2	28398509
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2D	3.87e-05	4	89	2	23129768
Pubmed	Smad6 is a protein kinase X phosphorylation substrate and is required for HL-60 cell differentiation.	PRKX SMAD6	3.87e-05	4	89	2	16491121
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2D	3.87e-05	4	89	2	24081332
Pubmed	NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.	IRF4 KDM6B	3.87e-05	4	89	2	37478314
Pubmed	Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.	KMT2D GLI1	3.87e-05	4	89	2	32738303
Pubmed	Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development.	GLI1 WT1	6.44e-05	5	89	2	28370670
Pubmed	Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk.	AFDN EPHA7	6.44e-05	5	89	2	10932185
Pubmed	Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.	KMT2C KMT2D	6.44e-05	5	89	2	31127101
Pubmed	Identification of an atypical monocyte and committed progenitor involved in fibrosis.	KDM6B TRIB1	6.44e-05	5	89	2	28002407
Pubmed	Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.	KDM6B TRIB1	6.44e-05	5	89	2	23515163
Pubmed	MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.	KMT2C KMT2D	6.44e-05	5	89	2	32601106
Pubmed	A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.	KMT2C KMT2D	6.44e-05	5	89	2	26744420
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	KMT2D GLI1 TLE4 WASF2 PAXX LRP1 CCDC86 TRIB1 VARS1 HOXB13	6.88e-05	857	89	10	25609649
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	MYPOP CAD RESF1 HDHD5 BCORL1 WT1 CCDC86	7.27e-05	396	89	7	26687479
Pubmed	Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.	SEMA3D TOX TLE4 PCSK6	7.93e-05	88	89	4	21491433
Pubmed	The role of kreisler in segmentation during hindbrain development.	HOXB4 EPHA7	9.65e-05	6	89	2	10395784
Pubmed	Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex.	WT1 KDM6B	9.65e-05	6	89	2	21378168
Pubmed	Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry.	GLI1 WT1	9.65e-05	6	89	2	24130328
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2C KMT2D	9.65e-05	6	89	2	17021013
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PRR12 KMT2D RESF1 TLE4 BCORL1 LRP1 ARHGAP21	1.02e-04	418	89	7	34709266
Pubmed	Epicardial-myocardial signaling directing coronary vasculogenesis.	WT1 TBX1 SMAD6	1.18e-04	37	89	3	20299672
Pubmed	Atlas of Hox gene expression in the developing kidney.	HOXB4 HOXC4 HOXD1	1.28e-04	38	89	3	15042701
Pubmed	Complete mutation analysis panel of the 39 human HOX genes.	HOXC4 HOXD1 HOXB13	1.28e-04	38	89	3	11857506
Pubmed	Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7.	RNF111 SMAD6	1.35e-04	7	89	2	14657019
Pubmed	Sequence and embryonic expression of the murine Hox-3.5 gene.	HOXB4 HOXC4	1.35e-04	7	89	2	1363091
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2C KMT2D	1.35e-04	7	89	2	30604749
Pubmed	Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.	KMT2C KMT2D	1.35e-04	7	89	2	36598580
Pubmed	Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations.	HOXB4 HOXC4	1.35e-04	7	89	2	8660891
Pubmed	EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm.	GCM2 TBX1	1.35e-04	7	89	2	33608392
Pubmed	Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.	GCM2 TBX1	1.35e-04	7	89	2	15581866
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2C KMT2D	1.35e-04	7	89	2	19556342
Pubmed	Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.	HOXB4 HOXC4 HOXD1	1.38e-04	39	89	3	33257809
Pubmed	AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.	WT1 TBX1 SMAD6	1.49e-04	40	89	3	24680892
Pubmed	Hox genes regulate the onset of Tbx5 expression in the forelimb.	HOXB4 HOXC4	1.79e-04	8	89	2	22872086
Pubmed	Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.	KMT2C KMT2D	1.79e-04	8	89	2	21447625
Pubmed	Pervasive translational regulation of the cell signalling circuitry underlies mammalian development.	GLI1 SAV1	1.79e-04	8	89	2	28195124
Pubmed	H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development.	KMT2C KMT2D	1.79e-04	8	89	2	30335158
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2C KMT2D	1.79e-04	8	89	2	23130995
Pubmed	Gcm1, a mammalian homolog of Drosophila glial cells missing.	GCM2 GLI1	1.79e-04	8	89	2	8814290
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2C KMT2D	1.79e-04	8	89	2	22266653
Pubmed	Nomenclature for human homeobox genes.	HOXB4 HOXC4 HOXD1	1.99e-04	44	89	3	1973146
Pubmed	Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.	KMT2D TBX1	2.30e-04	9	89	2	35296311
Pubmed	Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development.	SEMA3D WT1	2.30e-04	9	89	2	27160901
Pubmed	Hox proteins drive cell segregation and non-autonomous apical remodelling during hindbrain segmentation.	HOXB4 EPHA7	2.30e-04	9	89	2	24574009
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2C KMT2D	2.30e-04	9	89	2	22665483
Pubmed	Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.	RNF111 SMAD6	2.30e-04	9	89	2	16601693
Pubmed	Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code.	HOXB4 HOXC4	2.30e-04	9	89	2	10579975
Pubmed	An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.	GLI1 KDM6B	2.30e-04	9	89	2	25370275
Pubmed	Detection of homeobox genes in development and evolution.	HOXC4 HOXD1	2.30e-04	9	89	2	1720547
Pubmed	Region-specific gastrointestinal Hox code during murine embryonal gut development.	HOXB4 HOXC4	2.30e-04	9	89	2	11869294
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	AFDN EPHA7	2.30e-04	9	89	2	9707552
Pubmed	Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.	KMT2D KLF4	2.30e-04	9	89	2	26691508
Pubmed	Vertebrate homeobox gene nomenclature.	HOXB4 HOXC4 HOXD1	2.42e-04	47	89	3	1358459
Pubmed	A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.	HOXB4 HOXC4 HOXD1 HOXB13	2.46e-04	118	89	4	16971476
Pubmed	Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.	GLI1 WT1	2.88e-04	10	89	2	19842175
Pubmed	OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor.	OVOL1 RNF111	2.88e-04	10	89	2	35484112
Pubmed	Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse.	GLI1 TBX1	2.88e-04	10	89	2	12223417
Pubmed	Coordination of endothelial cell positioning and fate specification by the epicardium.	SEMA3D WT1	2.88e-04	10	89	2	34230480
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 KMT2C KMT2D RESF1 TLE4 BCORL1	2.91e-04	351	89	6	38297188
Pubmed	MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.	KMT2C KMT2D	3.51e-04	11	89	2	37012455
Pubmed	Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses.	IRF4 KLF4	3.51e-04	11	89	2	25992862
Interaction	TOP3B interactions	TYK2 MPP3 CCDC71L PRR12 KMT2C HOXB4 KMT2D CAD OVOL1 KIF26A FASTK GLI1 NFX1 MAPKBP1 KDM6B KLF4 FHIP1B DOCK6 TRIB1 ARHGAP21 HOXB13	1.00e-06	1470	88	21	int:TOP3B
Interaction	NCK2 interactions	MYPOP HOXC4 EFS WASF2 SIK2 AFDN VARS2 ARHGAP21	1.92e-05	262	88	8	int:NCK2
Interaction	SOX7 interactions	PRR12 KMT2C KMT2D RESF1 BCORL1	2.96e-05	82	88	5	int:SOX7
Interaction	IRF4 interactions	PRR12 KMT2C KMT2D IRF4 HOXB13	3.53e-05	85	88	5	int:IRF4
Interaction	GSC interactions	PRR12 KMT2C KMT2D TLE4 BCORL1	3.95e-05	87	88	5	int:GSC
Interaction	FOXI1 interactions	PRR12 KMT2C KMT2D TLE4 VARS1	5.16e-05	92	88	5	int:FOXI1
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	HOXC4 KMT2D NEUROD4 GLI1 FIGNL2 LRP1	1.69e-04	423	88	6	chr12q13
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	ASB16-AS1 MPP3 HOXB4 GJD3 KIF18B HOXB13	3.08e-04	473	88	6	chr17q21
Cytoband	16q24	VPS9D1 ZNF469	4.85e-04	17	88	2	16q24
Cytoband	17q21.31	ASB16-AS1 MPP3 KIF18B	5.40e-04	82	88	3	17q21.31
Cytoband	11q14.3	FAT3 AMOTL1	1.74e-03	32	88	2	11q14.3
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	UBAP1L RNF111 SMAD6	2.13e-03	132	88	3	chr15q22
Cytoband	12q13.3	HOXC4 LRP1	4.36e-03	51	88	2	12q13.3
GeneFamily	HOXL subclass homeoboxes	HOXB4 HOXC4 HOXD1 HOXB13	2.63e-05	52	60	4	518
GeneFamily	Aminoacyl tRNA synthetases, Class I	VARS2 VARS1	1.79e-03	19	60	2	131
GeneFamily	Gap junction proteins	GJA4 GJD3	2.40e-03	22	60	2	314
GeneFamily	PHD finger proteins	KMT2C KMT2D NFX1	3.33e-03	90	60	3	88
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	HOXB4 HOXC4 OVOL1 HOXD1 PRR5 WT1 SCNN1B TBX1	4.15e-06	272	89	8	M1938
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	KMT2C COL7A1 PARP4 OVOL1 FASTK WASF2 AMOTL1 NFX1 WDR81 SAV1 AFDN ARHGAP21 SMAD6	5.29e-06	843	89	13	M2356
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	HOXB4 HOXC4 OVOL1 HOXD1 PRR5 WT1 SCNN1B TBX1	5.40e-06	282	89	8	MM822
Coexpression	GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP	VPS9D1 KMT2C COL7A1 RESF1 HDHD5 CLDN19 FHIP1B	5.50e-06	200	89	7	M3523
Coexpression	GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP	COL7A1 ZBTB45 SAV1 MAPKBP1 PRKX SH2D5	4.59e-05	189	89	6	M6588
Coexpression	GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_UP	ASB16-AS1 CCDC71L VPS9D1 THBS3 HDHD5 KLF4	5.01e-05	192	89	6	M4156
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN	EFS TLE4 WASF2 TRIB1 ARHGAP21 EPHA7	6.29e-05	200	89	6	M4062
Coexpression	GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_UP	EFS GLI1 PCSK6 LRP1 WDR81 TRIB1	6.29e-05	200	89	6	M3852
Coexpression	GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11	TLE4 AMOTL1 ARHGAP21 SMAD6	6.35e-05	63	89	4	M18201
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	KMT2C SEMA3D SUSD4 HOXC4 RESF1 FAT3 AMOTL1 LPP BCORL1 SLITRK4 LRP1 KDM6B MFRP FHIP1B	5.09e-06	801	88	14	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000	SEMA3D FAT3 AMOTL1 LPP BCORL1 SLITRK4 LRP1 MFRP	1.12e-05	256	88	8	gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000	SEMA3D HOXC4 FAT3 LPP BCORL1 SLITRK4 LRP1	1.79e-05	197	88	7	gudmap_developingGonad_e16.5_epididymis_1000_k5
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.00e-06	165	89	6	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.00e-06	165	89	6	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.00e-06	165	89	6	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.00e-06	165	89	6	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 PCSK6 PRR5 N4BP3 TBX1	1.15e-06	169	89	6	f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCM2 C17orf99 PRR5 SIK2 IRF4 SH2D5	1.28e-06	172	89	6	24ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCM2 C17orf99 PRR5 SIK2 IRF4 SH2D5	1.28e-06	172	89	6	db5a31cafce4346fe459d7f35210823fd7004439
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 AMOTL1 DOCK6 TBX1	1.95e-06	185	89	6	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 AMOTL1 DOCK6 TBX1	1.95e-06	185	89	6	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SEMA3D SUSD4 PCSK6 PRR5 UBAP1L TBX1	2.28e-06	190	89	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 PCSK6 ROR1 WT1 LRP1 EPHA7	2.35e-06	191	89	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3 DOCK6	3.06e-06	200	89	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3 DOCK6	3.06e-06	200	89	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3 DOCK6	3.06e-06	200	89	6	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3 DOCK6	3.06e-06	200	89	6	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OVOL1 TOX KCNC3 KIF26A SCNN1B	1.32e-05	151	89	5	10da94037225a71844281ddcb395072250a78094
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MPP3 C17orf99 ROR1 KDM6B CRIP3	1.80e-05	161	89	5	78cc5bc488bc47726195a649946d414e6bfabf94
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SEMA3D PCSK6 UBAP1L N4BP3 TBX1	1.91e-05	163	89	5	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.96e-05	164	89	5	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.96e-05	164	89	5	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.96e-05	164	89	5	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 GJD3 PCSK6 TBX1	1.96e-05	164	89	5	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLITRK4 PRR5 IRF4 TRIB1 HOXB13	2.14e-05	167	89	5	8ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLITRK4 PRR5 IRF4 TRIB1 HOXB13	2.14e-05	167	89	5	a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	TPO KIF26A TBX1 SMAD6 EPHA7	2.20e-05	168	89	5	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 PCSK6 N4BP3 TBX1	2.33e-05	170	89	5	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 PCSK6 N4BP3 TBX1	2.33e-05	170	89	5	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3D SUSD4 PCSK6 N4BP3 TBX1	2.33e-05	170	89	5	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	SEMA3D PCSK6 DOCK6 SH2D5 TBX1	2.54e-05	173	89	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXC4 PRR5 IRF4 TRIB1 HOXB13	2.68e-05	175	89	5	28b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXC4 PRR5 IRF4 TRIB1 HOXB13	2.68e-05	175	89	5	ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MPP3 KLF4 N4BP3 DOCK6 SMAD6	3.07e-05	180	89	5	162cec1734e560c068cd61717e40e18dcf92308c
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MPP3 KLF4 N4BP3 DOCK6 SMAD6	3.07e-05	180	89	5	33c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 SEMA3D ZNF469 GLI1 LRP1	3.15e-05	181	89	5	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 GJD3 PCSK6 TBX1	3.15e-05	181	89	5	b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 SEMA3D ZNF469 GLI1 LRP1	3.15e-05	181	89	5	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 GJD3 PCSK6 TBX1	3.15e-05	181	89	5	cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 GJD3 PCSK6 TBX1	3.15e-05	181	89	5	ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GLI1 FAT3 ROR1 LRP1 EPHA7	3.32e-05	183	89	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D HOXC4 EFS GLI1 LRP1	3.49e-05	185	89	5	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MPP3 ROR1 SCNN1B AFDN OTUD7B	3.49e-05	185	89	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D HOXC4 EFS GLI1 LRP1	3.49e-05	185	89	5	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 KIF26A N4BP3 TBX1	3.49e-05	185	89	5	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 N4BP3 TBX1	3.59e-05	186	89	5	f23f21781a758541f59c06efa7739d26a03fb478
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 PCSK6 SLITRK4 WT1 LRP1	3.59e-05	186	89	5	a66da8453bb78f7e9f5f59452b3c50ae679d83c3
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SEMA3D KIF26A GJD3 TBX1	3.59e-05	186	89	5	9579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 N4BP3 TBX1	3.59e-05	186	89	5	0de87109da9324c597fadf2eb782f0f158afe832
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WASF2 WT1 AFDN KLF4 N4BP3	3.77e-05	188	89	5	8a87daf2851d9404df7c36f279db599574b47c69
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA3D TOX GLI1 FAT3 ROR1	3.77e-05	188	89	5	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WASF2 WT1 AFDN KLF4 N4BP3	3.77e-05	188	89	5	0f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 DOCK6 TBX1	3.77e-05	188	89	5	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D SUSD4 PCSK6 DOCK6 TBX1	3.77e-05	188	89	5	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WASF2 WT1 AFDN KLF4 N4BP3	3.77e-05	188	89	5	aec7485f1a9412bd3a62b70c801cb7f8dcca232d
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D THBS3 EFS LRP1 SH2D5	3.87e-05	189	89	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 PCSK6 DOCK6 TBX1	3.97e-05	190	89	5	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Lymphatic\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	TPO SEMA3D PRR5 DOCK6 TBX1	3.97e-05	190	89	5	8d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 PCSK6 DOCK6 TBX1	3.97e-05	190	89	5	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D SUSD4 PCSK6 DOCK6 TBX1	3.97e-05	190	89	5	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GJA4 HOXD1 SCNN1B UBAP1L TBX1	3.97e-05	190	89	5	103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HOXB4 SEMA3D PCSK6 SCNN1B TBX1	4.17e-05	192	89	5	5e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HOXB4 SEMA3D PCSK6 SCNN1B TBX1	4.17e-05	192	89	5	5f4f44f15d3a2846981e68296643a4634930a211
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA4 KIF26A KLF4 N4BP3 SMAD6	4.17e-05	192	89	5	6b69bb8fab9b470850eba1a070a500435ec233cd
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SEMA3D PCSK6 PRR5 SCNN1B TBX1	4.38e-05	194	89	5	9441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 AFDN KLF4 N4BP3 SMAD6	4.38e-05	194	89	5	f93f5148b136819d87faef89707dbaba07d6c2b5
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA3D PCSK6 DOCK6 TBX1 SMAD6	4.49e-05	195	89	5	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	PND03-Endothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 AFDN KLF4 N4BP3 SMAD6	4.60e-05	196	89	5	a529681d822a95dd1980b7b1c71dc61aaf0baecd
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D THBS3 PCSK6 ROR1 LRP1	4.60e-05	196	89	5	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D THBS3 PCSK6 ROR1 LRP1	4.60e-05	196	89	5	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	EFS NEUROD4 AFDN KDM6B PRKX	4.83e-05	198	89	5	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	EFS NEUROD4 AFDN KDM6B PRKX	4.83e-05	198	89	5	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SEMA3D PCSK6 PRR5 SCNN1B TBX1	4.83e-05	198	89	5	7a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 SEMA3D PCSK6 DOCK6 TBX1	4.83e-05	198	89	5	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 SEMA3D PCSK6 DOCK6 TBX1	4.83e-05	198	89	5	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C LRP1 KDM6B KLF4 TRIB1	4.83e-05	198	89	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA3D PCSK6 N4BP3 DOCK6 TBX1	5.06e-05	200	89	5	f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEMA3D PCSK6 N4BP3 DOCK6 TBX1	5.06e-05	200	89	5	e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Lymphatic\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SEMA3D PCSK6 N4BP3 DOCK6 TBX1	5.06e-05	200	89	5	4ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	RESF1 TLE4 AFDN KLF4 N4BP3	5.06e-05	200	89	5	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	TLE4 AFDN KLF4 N4BP3 DOCK6	5.06e-05	200	89	5	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	HOXB4 NEUROD4 AFDN KDM6B PRKX	5.06e-05	200	89	5	b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Cytl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FIGNL2 KLF4 TBX1 SMAD6	5.66e-05	104	89	4	5d9cd14e53a2f1060e528abf6c0694be9d72c356
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GCM2 GLI1 LRP1 SIK2	1.64e-04	137	89	4	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MPP3 HOXB4 PRR5 PRKX	1.89e-04	142	89	4	5690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FIGNL2 CLDN19 KDM6B N4BP3	1.94e-04	143	89	4	4122dcb742d3c8deff552b4dae9f2d239e6828f3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPP3 ZBTB45 FAT3 FIGNL2	2.15e-04	147	89	4	f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MPP3 ZBTB45 FAT3 FIGNL2	2.15e-04	147	89	4	ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCell	COVID-19-kidney-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3D PCSK6 PRR5 TBX1	2.21e-04	148	89	4	f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ASB16-AS1 OVOL1 KIF26A SCNN1B	2.39e-04	151	89	4	3744e4ed87703a97002e001afd16490d525a5128
ToppCell	Adult-Epithelial-basal_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL7A1 ZBTB45 EFS EPHA7	2.57e-04	154	89	4	38d346402417960044ae999e61f0092b46f2b591
Drug	Clioquinol [130-26-7]; Up 200; 13uM; PC3; HT_HG-U133A	SUSD4 HOXD1 EFS TLE4 ROR1 KDM6B KLF4	9.76e-06	190	89	7	4663_UP
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	GJA4 THBS3 NEUROD4 PRR5 LRP1 IRF4 TBX1	1.23e-05	197	89	7	5046_UP
Drug	Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A	GJA4 COL7A1 TOX NEUROD4 LRP1 AFDN KLF4	1.28e-05	198	89	7	5067_UP
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	8.79e-06	2	88	2	DOID:0080598 (implicated_via_orthology)
Disease	combined oxidative phosphorylation deficiency 20 (implicated_via_orthology)	VARS2 VARS1	8.79e-06	2	88	2	DOID:0111478 (implicated_via_orthology)
Disease	Colorectal Carcinoma	KMT2C COL7A1 CAD HOXD1 EFS SCNN1B LRP1 TBX1 CAPN10 EPHA7	4.63e-05	702	88	10	C0009402
Disease	autoimmune disease	TYK2 TPO LPP IRF4 NEURL4	1.73e-04	173	88	5	EFO_0005140
Disease	myoclonic-atonic epilepsy (implicated_via_orthology)	VARS2 VARS1	1.83e-04	7	88	2	DOID:0060475 (implicated_via_orthology)
Disease	mitochondrial encephalomyopathy (implicated_via_orthology)	VARS2 VARS1	2.43e-04	8	88	2	DOID:890 (implicated_via_orthology)
Disease	metachronous colorectal adenoma	CCDC71L FAT3 EPHA7	3.32e-04	45	88	3	EFO_0803377
Disease	neuroimaging measurement	TYK2 SEMA3D ZNF469 EFS TLE4 FAT3 GJD3 ROR1 KIF18B SH2D5 OTUD7B	3.35e-04	1069	88	11	EFO_0004346
Disease	Eczema	OVOL1 TLE4 LPP SIK2 TRIB1 OTUD7B	3.37e-04	310	88	6	HP_0000964
Disease	Microphthalmos	KMT2D MFRP	4.75e-04	11	88	2	C0026010
Disease	Thyroid preparation use measurement	TYK2 TPO LPP IRF4 NEURL4	4.90e-04	217	88	5	EFO_0009933
Disease	glucose metabolism measurement, age-related hearing impairment	ZNF469 TOX EPHA7	5.10e-04	52	88	3	EFO_0005782, EFO_0009367
Disease	interleukin 12 measurement	KCNC3 NFX1 KLF4	5.39e-04	53	88	3	EFO_0004753
Disease	autoimmune thyroid disease	TYK2 TPO LPP IRF4	5.60e-04	126	88	4	EFO_0006812
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	WT1 LRP1	5.69e-04	12	88	2	DOID:3827 (implicated_via_orthology)
Disease	disks large homolog 3 measurement	MPP3 CCDC71L	5.69e-04	12	88	2	EFO_0802472
Disease	Diffuse Large B-Cell Lymphoma	KMT2D GLI1 CCDC86	6.01e-04	55	88	3	C0079744
Disease	free androgen index	TYK2 ZNF469 MYPOP OVOL1 BCORL1 ARHGAP21	9.01e-04	374	88	6	EFO_0007005
Disease	fish consumption measurement	TOX FIGNL2 SIK2	9.36e-04	64	88	3	EFO_0010139
Disease	breast carcinoma (is_marker_for)	KMT2D AFDN KDM6B	1.02e-03	66	88	3	DOID:3459 (is_marker_for)
Disease	Abnormal behavior	PRR12 BCORL1	1.03e-03	16	88	2	C0233514
Disease	non-melanoma skin carcinoma	ZNF469 OVOL1 AMOTL1 LPP IRF4	1.20e-03	265	88	5	EFO_0009260
Disease	asthma, age at onset	OVOL1 LPP IRF4	1.21e-03	70	88	3	EFO_0004847, MONDO_0004979
Disease	urate measurement	COL7A1 THBS3 OVOL1 HOXD1 GLI1 LRP1 VARS2 CRIP3 VARS1	1.40e-03	895	88	9	EFO_0004531
Disease	X-11470 measurement	VARS2 VARS1	1.45e-03	19	88	2	EFO_0021241
Disease	leukemia (implicated_via_orthology)	HOXB4 HOXC4	1.45e-03	19	88	2	DOID:1240 (implicated_via_orthology)
Disease	Diuretic use measurement	CCDC71L OVOL1 WT1 SIK2	1.67e-03	169	88	4	EFO_0009928
Disease	Moderate albuminuria	VARS2 TRIB1 VARS1	1.78e-03	80	88	3	HP_0012594
Disease	serum albumin measurement	PRR12 COL7A1 WDR81 SAV1 IRF4 MAFIP TRIB1	1.97e-03	592	88	7	EFO_0004535
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	MPP3 PCSK6 TRIB1	2.19e-03	86	88	3	EFO_0008595, EFO_0020945
Disease	smoking behavior, BMI-adjusted waist-hip ratio	HOXC4 TRIB1 SMAD6	2.19e-03	86	88	3	EFO_0004318, EFO_0007788
Disease	orofacial cleft, sex interaction measurement	AMOTL1 LPP TRIB1	2.19e-03	86	88	3	EFO_0008343, MONDO_0000358
Disease	hair colour measurement	VPS9D1 ZNF469 KMT2D OVOL1 TLE4 LRP1 IRF4	2.44e-03	615	88	7	EFO_0007822
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	MPP3 COL7A1 PCSK6 DOCK6 TRIB1	2.77e-03	321	88	5	EFO_0004612, EFO_0004639
Disease	thyroid stimulating hormone measurement	TPO LPP SCNN1B PRKX SMAD6	2.84e-03	323	88	5	EFO_0004748
Disease	Squamous cell carcinoma of esophagus	KMT2C KMT2D FAT3	2.91e-03	95	88	3	C0279626
Disease	Sezary Syndrome	KMT2C KMT2D	2.94e-03	27	88	2	C0036920

Protein segments in the cluster

Peptide	Gene	Start	Entry
CTEEQTPPPRPEAYP	AFDN	1206	P55196
QPEYSPESPRCQPKP	CCDC86	106	Q9H6F5
SQPLVYIPPPSCGQP	BCORL1	446	Q5H9F3
PPPEYGVTSRPCQLP	AMOTL1	366	Q8IY63
CPEPERPNSSPQPYR	CLDN19	186	Q8N6F1
RPNSSPQPYRPGPSA	CLDN19	191	Q8N6F1
NPCFPFSVPEGPGPR	CAPN10	541	Q9HC96
PQPGVACSYLGPRPQ	ASB16-AS1	96	Q495Z4
YARCIPSNTRDPPGP	REC114	26	Q7Z4M0
LPPGPEPPRFVCYCE	PAXX	11	Q9BUH6
GPPCPPPVFPEDASY	MFRP	31	Q9BY79
PRQCPPGRPYPHQDS	OTUD7B	731	Q6GQQ9
RTQDPFLPYPPRSCP	FASTK	446	Q14296
EAYESFTCPPEPPGP	FHIP1B	706	Q8N612
VVVAPYNGGPPRTCP	KLF4	261	O43474
TSQDPYSQPPGTPRP	KMT2C	2126	Q8NEZ4
PSTPVGAYFCPPQPQ	MAFIP	31	Q8WZ33
YACAPPESQAPGVPT	IRF4	221	Q15306
RPSVPPPAAPQYAQC	HOXD1	71	Q9GZZ0
PSYVPPPQCQPGEFA	LRP1	846	Q07954
ACVPYAPSRPPGLPG	KDM6B	381	O15054
ALPAACSAPPPRPVY	PCSK6	56	P29122
FVPPRAPAACAPEPG	TPO	366	P07202
KYPCGESCPRPPETP	FAM47B	181	Q8NA70
GASVIYPPVPCGTRP	NFX1	751	Q12986
YPPVPCGTRPPECTQ	NFX1	756	Q12986
YNTQPVPVSGQCPPP	LPP	251	Q93052
ASLPRPAYSPRCPEP	LCA10	61	Q71F78
PDRTPPCLPGDPDYS	KIF26A	766	Q9ULI4
TQPPPDYLPSEPRPC	GLI1	866	P08151
GPPQNPPSSPYCGIV	PARP4	1386	Q9UKK3
SDPPYVACTRPPSAP	EPHA7	321	Q15375
LCPEPPGYTGPVTRT	KIF18B	581	Q86Y91
LGFCPPQPYREPEPS	OVOL1	36	O14753
SVPCYPPPAPGEFPE	PRR35	186	P0CG20
TVQRYAACRDPGPPP	HOXB4	61	P17483
PPPDPVGTYNPACAL	CCDC105	281	Q8IYK2
APQPPPPITYSLCGT	C17orf99	51	Q6UX52
PFCLPVSVDQPPPSY	DOCK6	671	Q96HP0
GPPQVPVRPMAYTPC	FAT3	4226	Q8TDW7
RVPAPPSPQPATYTC	IGHD	341	P01880
PPPRPSYPERQYSCT	HOXC4	56	P09017
YVVPPPARPCPTSGP	EFS	101	O43281
LYNPPTPSPGCTTPL	CRIP3	76	Q6Q6R5
PSRRPGPEPCAPPAY	GJD3	251	Q8N144
PPRPQASQPCSYPHI	MAPKBP1	916	O60336
YSSCRALVPDPPGPP	CCDC71L	101	Q8N9Z2
QPRPEPCPVYCPKGQ	COL7A1	1241	Q02388
YLPVGQGPSSPPCPT	GJA4	266	P35212
YCAQTGAALPPPPPA	FIGNL2	171	A6NMB9
CPGVPQGTSPAPVPY	HOXB13	66	Q92826
QPDTAPRSPNTGPYP	SCNN1B	591	P51168
PCYRCIFPQPPPAET	MOCS3	221	O95396
FQVCVRPGSYTPGPP	NEURL4	1511	Q96JN8
PSPQSLRKPPYDQPC	MPP3	306	Q13368
QAPPSLCVTPYPEPS	VARS1	1081	P26640
RPGCPPAPSISVAPY	VARS2	871	Q5ST30
SYQTRVPPLTPCPAP	SLITRK4	331	Q8IW52
FSRLCGPESPPPPYS	SMAD6	266	O43541
PAPHSGPCPSRLYPT	PRR5	311	P85299
GPCPSRLYPTTQPPE	PRR5	316	P85299
TQTDKRPPPPPYNCR	RESF1	271	Q9HCM1
NPELPCRYLTTPPPG	GCM2	361	O75603
PARRCYAVGPAQSPP	HDHD5	31	Q9BXW7
TYEEQDCGPPGRPPR	SH2D5	391	Q6ZV89
LPSAASPAPDYPTPC	SIK2	851	Q9H0K1
PPPPGLATCQSYSPD	PRR12	486	Q9ULL5
PYPRPGTCPSKTYDP	SEMA3D	391	O95025
YQPTGPPRVIQHCPP	ROR1	836	Q01973
CAPSVPRYDQPPPVT	SAV1	266	Q9H4B6
TPARTPGAEPPTYEC	ZBTB45	391	Q96K62
PPDYLSPPGSPCSPQ	TRIB1	56	Q96RU8
PQPPPQPSLSSCRHY	RNF111	631	Q6ZNA4
QPGSPPPRYQGPVHC	SLC25A45	136	Q8N413
RTPMAVPCPYPTPFG	TLE4	361	Q04727
GCPLPVDDQSPPAYP	SUSD4	401	Q5VX71
ACRYGPFGPPPPSQA	WT1	106	P19544
YVPPGPDNCRLVPNP	THBS3	671	P49746
CPSPEALSPEPPVYS	PRKX	31	P51817
DGTCYPPPPVPRQAS	CAD	1886	P27708
GCVENVDASSYPPPP	WASF2	236	Q9Y6W5
LPTQPAPSPLPCYQG	ZNF469	326	Q96JG9
CADPPQKTVPSDPPY	ZNF469	1456	Q96JG9
SPYTCLPPLGGAPQP	UBAP1L	236	F5GYI3
PPPRYDPCAAAAPGA	TBX1	46	O43435
YCPTPEATPQAGPPP	VPS9D1	546	Q9Y2B5
GNARNIPEPPPICYP	ARHGAP21	191	Q5T5U3
YPPPAQPAAAPDAPC	TOX	6	O94900
FEYRPVSQGLPPPCP	WDR81	846	Q562E7
NPREPAVYRCGPPGT	TYK2	116	P29597
QCPDFPYPVPPSEGC	nan	36	Q6ZPA2
PYPVPPSEGCPSGRL	nan	41	Q6ZPA2
KHIPRPPQPGSPNYC	KCNC3	561	Q14003
CPSPVTPRFQSPDPY	KMT2D	2436	O14686
LPEPPPPYEFSCSSA	N4BP3	241	O15049
SSQPPPPSACPQRYV	MYPOP	141	Q86VE0
LPDCSTPPYEGPLTP	NEUROD4	241	Q9HD90