Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

UBA5 KIF6 MYH10 ABCA3 ABCB7 ATRX TCP1 ANXA1 MCM2 DNAH7 UBA1 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 ATP11A ATP2A2 KIF17

1.06e-0761414519GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF6 ABCA3 ABCB7 ATRX TCP1 MCM2 DNAH7 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 ATP11A ATP2A2 KIF17

7.93e-0744114515GO:0016887
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

2.78e-05491455GO:0140359
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF6 ABCA3 ABCB7 ATRX SEPTIN4 TCP1 DCP2 MCM2 DNAH7 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 RASEF ATP11A ATP2A2 KIF17

3.84e-0583914518GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF6 ABCA3 ABCB7 ATRX SEPTIN4 TCP1 DCP2 MCM2 DNAH7 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 RASEF ATP11A ATP2A2 KIF17

3.90e-0584014518GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF6 ABCA3 ABCB7 ATRX SEPTIN4 TCP1 DCP2 MCM2 DNAH7 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 RASEF ATP11A ATP2A2 KIF17

3.90e-0584014518GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF6 ABCA3 ABCB7 ATRX SEPTIN4 TCP1 MCM2 DNAH7 ABCB10 ABCA6 ABCA5 MOV10L1 HELZ2 RASEF ATP11A ATP2A2 KIF17

4.87e-0577514517GO:0017111
GeneOntologyMolecularFunctionRNA nuclease activity

EXOSC9 KHNYN DCP2 AGO1 SND1 NYNRIN HELZ2

6.16e-051361457GO:0004540
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5 ATP2A2

1.45e-041091456GO:0042626
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

EXOSC9 CMTR1 ATRX ANXA1 POLH KHNYN DCP2 MCM2 ALKBH8 AGO1 SND1 NYNRIN MOV10L1 HELZ2

2.60e-0464514514GO:0140640
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS2 PRPS1

5.16e-0451452GO:0004749
GeneOntologyMolecularFunctionphospholipid binding

ZFYVE16 ANXA1 PCLO RNF34 SCARB2 SVIL OSBPL10 PLD1 NCF1C NCF1B ARAP1 CPNE7

6.69e-0454814512GO:0005543
GeneOntologyMolecularFunctionsyntaxin-1 binding

STXBP2 STXBP3 SNAP25

6.79e-04241453GO:0017075
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS2 PRPS1

7.71e-0461452GO:0016778
GeneOntologyMolecularFunctionlipid binding

ZFYVE16 ANXA1 PCLO SH3GL2 SHBG ACOT7 RNF34 INPP4B SCARB2 SVIL OSBPL10 SNAP25 PLD1 NCF1C NCF1B ARAP1 CPNE7

8.40e-0498814517GO:0008289
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

EXOSC9 CMTR1 KHNYN DCP2 ALKBH8 AGO1 SND1 NYNRIN MOV10L1 HELZ2

9.56e-0441714510GO:0140098
GeneOntologyMolecularFunctionRNA polymerase binding

PPIB AGO1 BRD4 RPRD2

1.28e-03651454GO:0070063
GeneOntologyMolecularFunctionnuclease activity

EXOSC9 KHNYN DCP2 AGO1 SND1 NYNRIN HELZ2

1.52e-032311457GO:0004518
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF6 MYH10 DNAH7 MYL6B KIF17

1.71e-031181455GO:0003774
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5 ATP2A2

1.93e-031781456GO:0015399
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCA3 PRELID2 OSBPL10 ATP11A

2.07e-03741454GO:0005548
GeneOntologyMolecularFunctionmagnesium ion binding

PRPS2 SEPTIN4 SRR MOV10L1 PKLR ATP11A PRPS1

2.21e-032471457GO:0000287
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PALD1 EXOSC9 CES5A KHNYN DCP2 ACOT7 H6PD INPP4B AGO1 SND1 NYNRIN PTPRQ HELZ2 PLD1

2.26e-0380714514GO:0016788
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1C NCF1B

2.27e-03101452GO:0016176
GeneOntologyMolecularFunctionubiquitin-like modifier activating enzyme activity

UBA5 UBA1

2.27e-03101452GO:0008641
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

ARG1 NCF1C NCF1B

1.05e-0571403GO:0070947
GeneOntologyCellularComponentribbon synapse

PCLO SH3GL2 SNAP25 ATP2A2

6.33e-05321424GO:0097470
GeneOntologyCellularComponentcell body

MYH10 SEPTIN4 TCP1 AZIN2 PARK7 PCLO SH3GL2 ACOT7 SRR TTLL7 ARG1 CNNM4 SLC8A3 AKAP9 SNAP25 NCF1C NCF1B

1.93e-0492914217GO:0044297
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS2 PRPS1

4.52e-0451422GO:0002189
GeneOntologyCellularComponentneuronal cell body

MYH10 SEPTIN4 AZIN2 PCLO SH3GL2 ACOT7 SRR TTLL7 ARG1 CNNM4 SLC8A3 AKAP9 SNAP25 NCF1C NCF1B

5.68e-0483514215GO:0043025
GeneOntologyCellularComponentsomatodendritic compartment

MYH10 SEPTIN4 IFT57 AZIN2 FAT3 PCLO SH3GL2 ANKS1B ACOT7 SRR TTLL7 ARG1 CNNM4 SLC8A3 AKAP9 SNAP25 NCF1C KIF17 NCF1B

6.59e-04122814219GO:0036477
GeneOntologyCellularComponentdendrite

MYH10 SEPTIN4 IFT57 AZIN2 FAT3 PCLO SH3GL2 ANKS1B TTLL7 CNNM4 SLC8A3 AKAP9 NCF1C KIF17 NCF1B

7.50e-0485814215GO:0030425
GeneOntologyCellularComponentdendritic tree

MYH10 SEPTIN4 IFT57 AZIN2 FAT3 PCLO SH3GL2 ANKS1B TTLL7 CNNM4 SLC8A3 AKAP9 NCF1C KIF17 NCF1B

7.68e-0486014215GO:0097447
GeneOntologyCellularComponentspecific granule

ARG1 STXBP2 STXBP3 ATP11A SNAP25 PLD1

7.95e-041601426GO:0042581
GeneOntologyCellularComponentpericentriolar material

TCP1 AKAP9 TUBE1

8.88e-04281423GO:0000242
GeneOntologyCellularComponentGolgi apparatus subcompartment

AZIN2 PCLO POSTN AKAP9 PRKD1 SNAP25 PLD1 VPS51 ECE2 ARAP1

9.12e-0444314210GO:0098791
GeneOntologyCellularComponentanchoring junction

ANXA1 PARK7 TRPC4 ITGA2 PPIB DES SLC8A3 UBA1 XIRP2 SCARB2 SVIL PRKAR2A TLN2 PRKD1 ATP2A2 EPB41L2

9.87e-0497614216GO:0070161
GeneOntologyCellularComponentcell cortex

MYH10 SEPTIN4 PCLO TRPC4 BFSP1 PDE4DIP PRKD1 SNAP25 EPB41L2

9.99e-043711429GO:0005938
GeneOntologyCellularComponentneuromuscular junction

MYH10 PCLO POSTN DES SLC8A3

1.01e-031121425GO:0031594
GeneOntologyCellularComponenttrans-Golgi network

AZIN2 PCLO POSTN PRKD1 SNAP25 VPS51 ECE2 ARAP1

1.19e-033061428GO:0005802
DomainABC_tran

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

3.01e-05481415PF00005
DomainABC_TRANSPORTER_2

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

3.01e-05481415PS50893
DomainABC_TRANSPORTER_1

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

3.33e-05491415PS00211
DomainABC_transporter-like

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

3.68e-05501415IPR003439
DomainABC_A

ABCA3 ABCA6 ABCA5

8.82e-05121413IPR026082
DomainAAA

ABCA3 ABCB7 DNAH7 ABCB10 ABCA6 ABCA5 HELZ2

1.12e-041441417SM00382
DomainAAA+_ATPase

ABCA3 ABCB7 DNAH7 ABCB10 ABCA6 ABCA5 HELZ2

1.12e-041441417IPR003593
DomainPRPP_SYNTHASE

PRPS2 PRPS1

1.69e-0431412PS00114
DomainPRib_PP_synth_CS

PRPS2 PRPS1

1.69e-0431412IPR000842
DomainABC_transporter_CS

ABCA3 ABCB7 ABCB10 ABCA5

2.79e-04421414IPR017871
DomainDUF21

CNNM2 CNNM4

3.36e-0441412IPR002550
DomainDUF21

CNNM2 CNNM4

3.36e-0441412PF01595
DomainPribosyltran_N

PRPS2 PRPS1

5.58e-0451412PF13793
DomainPribosyl_synth

PRPS2 PRPS1

5.58e-0451412PF14572
DomainRib-P_diPkinase

PRPS2 PRPS1

5.58e-0451412IPR005946
DomainPribosyltran_N

PRPS2 PRPS1

5.58e-0451412IPR029099
PathwayKEGG_ABC_TRANSPORTERS

ABCA3 ABCB7 ABCB10 ABCA6 ABCA5

2.79e-05441155M11911
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH10 ILF3 SEPTIN4 TCP1 ANXA1 PARK7 PCLO HNRNPM ANKS1B ACOT7 ITGA2 PPIB JMY UBA1 FBXL16 AGO1 SND1 SVIL PDE4DIP OSBPL10 PRKAR2A TLN2 VPS51 ATP2A2 EPB41L2 PRPS1

3.85e-1014311482637142655
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

CCDC22 ILF3 CASP14 CMTR1 ZFYVE16 PARK7 POLH NACA PPIB RIF1 BAZ1A PRKAR2A TLN2 RPRD2 CPSF2

1.98e-094721481538943005
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EXOSC9 ILF3 CASP14 TCP1 ANXA1 NACA MCM2 PPIB ARG1 RIF1 URB1 UBA1 STXBP2 SND1 BAZ1A VANGL1 MYL6B SVIL CPSF2 ATP2A2 EPB41L2

2.79e-0910241482124711643
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

PRPS2 EXOSC9 MYH10 ILF3 TCP1 ANXA1 PARK7 KHNYN NACA HNRNPM ACOT7 MCM2 PPIB UBA1 STXBP2 SND1 SVIL PRKAR2A ATP2A2 EPB41L2 PRPS1

2.05e-0811491482135446349
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYH10 ILF3 PARK7 TRPC4 SH3GL2 HNRNPM ANKS1B PPIB UBA1 AGO1 AKAP9 SVIL PDE4DIP PRKAR2A TLN2 PRKD1 CPSF2 ARHGEF26 EPB41L2

3.12e-089631481928671696
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EXOSC9 MYH10 ILF3 ATRX TCP1 PARK7 PCLO NACA HNRNPM MCM2 PPIB RIF1 URB1 UBA1 STXBP3 SND1 BAZ1A PRKAR2A TLN2 BOD1L1 ATP2A2 EPB41L2 PRPS1

3.98e-0814251482330948266
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

BDP1 KIF6 ILF3 FAM185A TRPC4 SH3GL2 PYROXD2 ANKS1B CUL9 TTLL7 TMEM132D RIN2 MOV10L1 RASEF PRKD1 CPSF2 CLEC16A

7.83e-088141481723251661
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PALD1 MYH10 ILF3 ATRX ZFYVE16 TCP1 PARK7 NACA HNRNPM KDM3B ACOT7 RIF1 UBA1 SND1 BAZ1A RPRD2 BOD1L1 EPB41L2

1.05e-079341481833916271
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PALD1 MYH10 ZFYVE16 KHNYN CUL9 ADCY6 AKAP9 PDE4DIP BOD1L1 KIF17 CLEC16A SENP7

1.96e-074071481212693553
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

UBA5 RNF130 ILF3 ATRX TCP1 HNRNPM RNF17 RIF1 SND1 BRD4 TLN2 CPSF2 VPS51 ARAP1

2.19e-075821481420467437
Pubmed

Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis.

PARK7 NCF1C NCF1B

3.01e-074148326021615
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

MYH10 ILF3 CASP14 TCP1 ANXA1 PARK7 NACA HNRNPM ACOT7 MCM2 PPIB ARG1 UBA1 SND1 HELZ2 ATP2A2

3.62e-078031481636517590
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYH10 CCDC22 ZFYVE16 TCP1 IFT57 PPIB POSTN CNNM4 RIF1 UBA1 FBXL16 AKAP9 STXBP3 VANGL1 SVIL TMF1 CPSF2 ATP2A2

5.71e-0710491481827880917
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PRPS2 MYH10 ILF3 ATRX MTRES1 PCLO HNRNPM ANKS1B RNF17 PPIB ADCY6 SCML4 DES STXBP2 KIAA0825 SND1 BAZ1A BOD1L1 ATP11A ATP2A2 PRPS1

8.80e-0714421482135575683
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

MYH10 ILF3 CASP14 TCP1 TRPC4 NACA HNRNPM MCM2 PPIB UBA1 SND1 ATP2A2

1.05e-064771481231300519
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYH10 CCDC22 ILF3 CASP14 TCP1 ANXA1 PARK7 NACA HNRNPM ACOT7 MCM2 PPIB ARG1 RIF1 URB1 UBA1 SND1 BAZ1A ATP2A2 EPB41L2

1.31e-0613531482029467282
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EXOSC9 MYH10 ILF3 TCP1 ANXA1 DCP2 NACA KBTBD8 PPIB RIF1 AKAP9 BAZ1A MYL6B PCSK6 SVIL HELZ2 PLD1 CPSF2 EPB41L2 CPNE7

1.60e-0613711482036244648
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EXOSC9 ATRX TCP1 HNRNPM RIF1 UBA1 SND1 BAZ1A BOD1L1 CPSF2

1.75e-063321481032786267
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MYH10 ANXA1 PARK7 PCLO SH3GL2 NACA HNRNPM ANKS1B UBA1 KCNQ5 PDE4DIP PRKAR2A TLN2 SNAP25 VPS51 ATP2A2 CLEC16A EPB41L2

1.84e-0611391481836417873
Pubmed

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model.

MYH10 ANXA1 PARK7 NACA HNRNPM UBA1 MYL6B

1.92e-06135148731405213
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MYH10 ILF3 TCP1 ANXA1 PARK7 PCLO HNRNPM ACOT7 PPIB AKAP9 STXBP3 SND1 MOV10L1 ATP2A2 PRPS1

2.02e-068071481530575818
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

PRPS2 TCP1 ANXA1 PPIB UBA1 STXBP3 SND1 MYL6B SCARB2 ATP2A2 PRPS1

2.13e-064221481127342126
Pubmed

ATP-mediated killing of intracellular mycobacteria by macrophages is a P2X(7)-dependent process inducing bacterial death by phagosome-lysosome fusion.

PLD1 NCF1C NCF1B

2.61e-067148311544318
Pubmed

Cloning and characterization of mouse intestinal MUC3 mucin: 3' sequence contains epidermal-growth-factor-like domains.

ZP3 NCF1C NCF1B

2.61e-06714839494100
Pubmed

Cloning and functional expression of the mouse homologue of p47phox.

ZP3 NCF1C NCF1B

2.61e-06714838119734
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

CMTR1 ATRX TCP1 PARK7 NACA HNRNPM KDM3B UBA1 RPRD2 ATP2A2

3.33e-063571481037059091
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

EXOSC9 MYH10 ILF3 ATRX ANXA1 RIF1 BRD4 RPRD2 BOD1L1

3.76e-06283148930585729
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CNNM2 ABCB7 CCDC22 CMTR1 LSM3 URB1 AKAP9 STXBP3 SND1 MYL6B BRD4 PCSK6 PDE4DIP PRKAR2A

4.56e-067541481433060197
Pubmed

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.

ILF3 CASP14 HNRNPM PPIB ARG1 AGO1 CPSF2

4.82e-06155148733838681
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

ILF3 TCP1 NACA HNRNPM RIF1 URB1 UBA1 SND1

5.14e-06221148829991511
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 RNF130 MYH10 SGSM1 ATRX H6PD ZP3 CNNM4 KCNQ5 RIN2 RASEF RPRD2 BOD1L1 ATP11A PRKD1 ARHGEF26 CLEC16A ARAP1 EVI5L CPNE7

5.53e-0614891482028611215
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

UBA5 ABCB7 ZFYVE16 TCP1 PARK7 NACA HNRNPM ACOT7 SRR UBA1 ABCB10 ATP2A2 EPB41L2 TANGO6 PRPS1

5.59e-068781481537223481
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KDM3B ADCY6 URB1 HELZ2 TLN2 RPRD2 CLEC16A ARAP1

5.87e-06225148812168954
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ILF3 ATRX KDM3B MCM2 ADCY6 RIF1 UBA1 BRD4 SVIL HELZ2 TLN2 CPSF2 ATP2A2 EPB41L2

6.14e-067741481415302935
Pubmed

Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance.

ZP3 NCF1C NCF1B

6.23e-069148310433265
Pubmed

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.

MYH10 ILF3 TCP1 ANXA1 NACA PPIB MYL6B ATP2A2 CPNE7

6.89e-06305148933194618
Pubmed

Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling.

MYH10 TCP1 MYL6B MOV10L1 CPSF2 ATP2A2 PRPS1

7.55e-06166148734687317
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

AZIN2 DNAH7 RIF1 AGO1 KCNQ5 XIRP2 NYNRIN PDE4DIP

7.57e-06233148837704626
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

PRPS2 MYH10 TCP1 ANXA1 NACA HNRNPM PPIB DES UBA1 MYL6B SVIL EPB41L2

7.71e-065801481235676659
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

MYH10 ABCB7 ILF3 HNRNPM CNNM4 URB1 UBA1 STXBP3 SND1 SCARB2 EPB41L2

7.82e-064841481131995728
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

MYH10 ATRX MCM2 RIF1 UBA1 BAZ1A BRD4 PRKAR2A CPSF2 EPB41L2

7.91e-063941481027248496
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

ATRX PARK7 BFSP1 SNED1 RIF1 UBA1 VANGL1

8.17e-06168148730631154
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

MYH10 ILF3 TCP1 ANXA1 HNRNPM ACOT7 MCM2 PPIB UBA1 SND1

8.45e-063971481021319273
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CASP14 ANXA1 SH3GL2 NACA MCM2 PPIB RIF1 UBA1 MYL6B PRKAR2A CPSF2 ARHGEF26 EPB41L2 ARAP1 EVI5L

9.24e-069161481532203420
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

MYH10 ANXA1 PARK7 PCLO MCM2 STXBP3 SVIL PRKAR2A TLN2 BOD1L1 PRPS1

1.02e-054981481136634849
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

PALD1 ILF3 ZFYVE16 TCP1 HNRNPM PPIB UBA1 SND1 VANGL1 BOD1L1 ARHGEF26 ATP2A2 EPB41L2

1.14e-057081481339231216
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

MYH10 ILF3 CASP14 TCP1 ANXA1 HNRNPM ARG1 UBA1 SND1

1.20e-05327148931409639
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PRPS2 PALD1 EXOSC9 ATRX IFT57 MCM2 DPP8 ADCY6 POSTN CNNM4 RIF1 UBA1 SND1 MYL6B PTPRQ PRKD1 VPS51 CCDC144A

1.40e-0513211481827173435
Pubmed

Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.

ADCY6 EPB41L2

1.80e-052148231383768
Pubmed

Functional pseudogenes inhibit the superoxide production.

NCF1C NCF1B

1.80e-052148226086043
Pubmed

EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.

ANKS1B TUBE1

1.80e-052148219851462
Pubmed

CGIN1: a retroviral contribution to mammalian genomes.

KHNYN NYNRIN

1.80e-052148219561090
Pubmed

Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction.

DES PDE4DIP

1.80e-052148234289528
Pubmed

[Increased activity of PRPP synthetase].

PRPS2 PRPS1

1.80e-052148218409517
Pubmed

Adipose-specific knockout of Protein Kinase D1 suppresses de novo lipogenesis in mice via SREBP1c-dependent signaling.

SREBF1 PRKD1

1.80e-052148233675805
Pubmed

A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models.

PRKD1 PLD1

1.80e-052148223178798
Pubmed

PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.

PRPS2 PRPS1

1.80e-052148233493137
Pubmed

Dimerization of the CNNM extracellular domain.

CNNM2 CNNM4

1.80e-052148238149326
Pubmed

Mg2+-dependent interactions of ATP with the cystathionine-β-synthase (CBS) domains of a magnesium transporter.

CNNM2 CNNM4

1.80e-052148224706765
Pubmed

Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.

PRPS2 PRPS1

1.80e-05214822537655
Pubmed

Munc18-syntaxin complexes and exocytosis in human platelets.

STXBP2 STXBP3

1.80e-052148212649283
Pubmed

A protein interaction landscape of breast cancer.

MYH10 ILF3 CASP14 ANXA1 PARK7 HNRNPM ACOT7 CUL9 UBA1 SND1 RIN2 SVIL

1.86e-056341481234591612
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

UBA5 MYH10 ILF3 TCP1 HNRNPM MCM2 RIF1 UBA1 SND1 PRKAR2A ATP2A2 EPB41L2

1.98e-056381481233239621
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

MYH10 ILF3 TCP1 ANXA1 HNRNPM SND1 MYL6B ATP2A2

2.08e-05268148833024031
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH10 ABCB7 ANXA1 PARK7 HNRNPM MCM2 ITGA2 DES UBA1 ABCB10 RASEF ATP2A2

2.27e-056471481226618866
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

ILF3 CASP14 ATRX ANXA1 NACA HNRNPM MCM2 PPIB ARG1 RIF1 SVIL ATP2A2

2.45e-056521481231180492
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

MYH10 ILF3 TCP1 ANXA1 PARK7 SH3GL2 HNRNPM ACOT7 UBA1 SNAP25 EPB41L2

2.63e-055521481136293380
Pubmed

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.

MYH10 ANXA1 AKAP9 PDE4DIP PRKAR2A

2.73e-0582148530274258
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

ILF3 TCP1 NACA RIF1 SND1 BRD4 CPSF2

2.78e-05203148722083510
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TCP1 HNRNPM KDM3B DNAH7 RIF1 VANGL1 PKLR OSBPL10 TMF1 PLD1 CLEC16A EPB41L2 PRPS1

3.01e-057771481335844135
Pubmed

RNA binding proteins co-localize with small tau inclusions in tauopathy.

TCP1 SRR PPIB ARG1 UBA1 SNAP25 ATP2A2 PRPS1

3.07e-05283148830068389
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

ILF3 CMTR1 PCLO HNRNPM SRR AGO1 SND1 NYNRIN PRKD1 PLD1

3.09e-054621481031138677
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

ANXA1 ITGA2 PPIB SCARB2 SVIL PRKAR2A TLN2 EPB41L2

3.22e-05285148821423176
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CMTR1 TCP1 NACA UBA1 TLN2 BOD1L1 ATP2A2

3.24e-05208148733230847
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

CASP14 ANXA1 PARK7 NACA ACOT7 MCM2 DES UBA1 SND1 TMF1 PRKAR2A ATP2A2 PRPS1

3.38e-057861481329128334
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CNNM2 ILF3 TCP1 PARK7 PPIB CNNM4 RIF1 UBA1 AGO1 VANGL1 ATP2A2

3.69e-055731481128330616
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MYH10 ABCB7 ZFYVE16 TCP1 PARK7 KDM3B MCM2 UBA1 SND1 BAZ1A VANGL1 SCARB2 PRKAR2A BOD1L1 ATP11A ATP2A2 EPB41L2

4.00e-0512971481733545068
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

CNNM2 CASP14 HNRNPM PPIB ARG1 AKAP9 PDE4DIP PRKAR2A TRPM8

4.06e-05382148937249651
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PALD1 EXOSC9 MYH10 ABCB7 CCDC22 TCP1 NACA MCM2 JMY CNNM4 URB1 SND1 MYL6B SCARB2 SNAP25 ATP2A2 EVI5L PRPS1

4.33e-0514401481830833792
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PRPS2 MYH10 ILF3 TCP1 NACA HNRNPM KDM3B ACOT7 MCM2 PPIB STXBP2 ABCB10 SND1 PKLR CPSF2 ATP2A2 PRPS1

4.88e-0513181481730463901
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

ABCB7 ATRX UBA1

4.91e-0517148319571810
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1C NCF1B

5.38e-053148227044504
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1C NCF1B

5.38e-053148218787174
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1C NCF1B

5.38e-053148224873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1C NCF1B

5.38e-053148222184329
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1C NCF1B

5.38e-053148233545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1C NCF1B

5.38e-053148220142487
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1C NCF1B

5.38e-053148225565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1C NCF1B

5.38e-053148239357591
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1C NCF1B

5.38e-053148211435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1C NCF1B

5.38e-053148231118934
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1C NCF1B

5.38e-053148216041040
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS2 PRPS1

5.38e-05314821314091
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1C NCF1B

5.38e-053148218703411
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1C NCF1B

5.38e-053148217307863
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1C NCF1B

5.38e-053148227829407
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1C NCF1B

5.38e-053148222376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1C NCF1B

5.38e-053148223918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1C NCF1B

5.38e-053148228274989
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1C NCF1B

5.38e-053148212364355
InteractionPPIA interactions

RNF130 CCDC22 ILF3 CASP14 CMTR1 ZFYVE16 TCP1 ANXA1 PARK7 POLH NACA HNRNPM ACOT7 MCM2 PPIB RIF1 BAZ1A PRKAR2A TLN2 RPRD2 CPSF2 SENP7

3.47e-0788814422int:PPIA
InteractionSUMO2 interactions

EXOSC9 ATRX TCP1 ANXA1 PARK7 NACA HNRNPM PPIB RIF1 UBA1 SND1 BAZ1A BRD4 BOD1L1 ZCCHC7 CPSF2 SENP7

1.15e-0659114417int:SUMO2
InteractionCCDC8 interactions

ILF3 CASP14 TCP1 NACA CUL9 MCM2 ARG1 UBA1 AGO1 STXBP2 SND1 BAZ1A VANGL1 MYL6B SVIL ATP2A2 EPB41L2

4.66e-0665614417int:CCDC8
InteractionKCTD13 interactions

MYH10 ILF3 SEPTIN4 TCP1 ANXA1 PARK7 PCLO HNRNPM ANKS1B ACOT7 ITGA2 PPIB JMY LSM3 UBA1 FBXL16 AGO1 SND1 SVIL OSBPL10 PRKAR2A TLN2 VPS51 ATP2A2 EPB41L2

1.74e-05139414425int:KCTD13
GeneFamilyATP binding cassette subfamily A

ABCA3 ABCA6 ABCA5

5.72e-05141003805
GeneFamilyUbiquitin like modifier activating enzymes

UBA5 UBA1

1.32e-03101002100
GeneFamilyATP binding cassette subfamily B

ABCB7 ABCB10

1.61e-03111002806
GeneFamilyUPF1 like RNA helicases

MOV10L1 HELZ2

1.61e-031110021169
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYH10 CNNM2 FAT3 TRPC4 ANKS1B INPP4B TTLL7 KCNQ5 SVIL PRKD1

7.89e-101881481034e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYH10 CNNM2 FAT3 TRPC4 ANKS1B INPP4B TTLL7 KCNQ5 PRKD1 ARHGEF26

8.31e-10189148106b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCelldroplet-Liver-Npc-21m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNNM2 CCDC22 KHNYN MCM2 CNNM4 PLD1 TUBE1

5.95e-097514877f3be37cc378ee115fcb4b0eb9653fc77447aa0a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX PCLO TTLL7 RIF1 AKAP9 ABCA5 BOD1L1 ZCCHC7 ATP2A2

1.96e-0819514897796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH10 FAT3 ANKS1B INPP4B TTLL7 DES SVIL TLN2

1.21e-071731488cb6389536195443633adb06e5f1b7483530773d1
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MYH10 SEPTIN4 FAT3 TRPC4 ITGA2 INPP4B SCN7A PRKD1

2.80e-0719314885896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

MYH10 FAT3 TRPC4 INPP4B SNED1 ABCA6 SCN7A PRKD1

3.02e-071951488603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX PCLO TTLL7 RIF1 AKAP9 BOD1L1 ZCCHC7 ATP2A2

3.02e-0719514883e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

MYH10 POSTN SNED1 ABCA6 SCN7A PRKD1 SNAP25 EPB41L2

3.27e-071971488f1c8936986123a3151140c374fcd62d6705c530b
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

MYH10 SEPTIN4 FAT3 ITGA2 AKAP9 SCN7A KANK4 SNAP25

3.40e-071981488e0e47cf65774191981840b22905b2094b95abe0f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

ILF3 HNRNPM DES AKAP9 SCN7A TLN2 BOD1L1 EPB41L2

3.67e-0720014887c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

MYH10 FAT3 INPP4B TTLL7 DES SVIL TLN2

2.43e-061801487d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFYVE16 KHNYN KDM3B TNFRSF21 ABCB10 SND1

2.52e-061161486f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

MYH10 FAT3 TRPC4 ANKS1B INPP4B TTLL7 KCNQ5

2.71e-061831487818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYH10 FAT3 TRPC4 ANKS1B TTLL7 KCNQ5 PRKD1

2.71e-061831487cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 SH3GL2 ITGA2 KANK4 OSBPL10 RASEF ATP11A

3.23e-0618814874bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 ANKS1B TTLL7 DES KCNQ5 SVIL ARHGEF26

3.47e-0619014872e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 ANKS1B TTLL7 DES KCNQ5 SVIL ARHGEF26

3.47e-0619014870028f886c789ba238c031eae5d96acaed4af8c25
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SGSM1 CMTR1 SEPTIN4 ANKS1B ETNPPL EPB41L2

3.71e-06124148680526f503e1477b9455d10f27f7e6b56caea3a66
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH10 FAT3 ITGA2 INPP4B ABCA6 SCN7A PRKD1

3.72e-06192148799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

MYH10 FAT3 TRPC4 ITGA2 ABCA6 SCN7A SNAP25

3.85e-061931487ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 ABCA3 IFT57 DNAH7 CFAP54 RASEF ATP11A

3.85e-061931487bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYH10 FAT3 ABCA6 PDE4DIP SCN7A TLN2 PRKD1

3.98e-061941487e93de9428c986b8943fc169258847c650cfab0e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC170 SEPTIN4 TRPC4 INPP4B ABCA6 KANK4 EPB41L2

3.98e-061941487cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC170 SEPTIN4 TRPC4 INPP4B ABCA6 KANK4 EPB41L2

3.98e-061941487ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

MYH10 FAT3 TRPC4 ITGA2 INPP4B ABCA6 SCN7A

4.12e-06195148761c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYH10 PCLO SH3GL2 ANKS1B KCNQ5 ABCA5 SNAP25

4.26e-061961487676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 TRPC4 TTLL7 POSTN DES SVIL EPB41L2

4.26e-0619614871522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 TRPC4 TTLL7 POSTN DES SVIL EPB41L2

4.26e-0619614871c8294014713684b50885e638668f2ce75f357f0
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

MYH10 SEPTIN4 FAT3 ITGA2 ABCA6 SCN7A SNAP25

4.40e-061971487156155c2f0c1a2461e45803da578af18ee221660
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

MYH10 SEPTIN4 FAT3 ITGA2 ABCA6 SCN7A SNAP25

4.40e-061971487d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

ATRX FAT3 PPIB JMY AKAP9 BRD4 BOD1L1

4.70e-06199148718a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

ATRX PPIB AKAP9 BAZ1A BRD4 TMF1 BOD1L1

4.70e-06199148753ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MYH10 FAT3 ITGA2 ABCA6 SCN7A SNAP25 EPB41L2

4.86e-062001487aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 PCLO SH3GL2 ANKS1B KCNQ5 ABCA5 SNAP25

4.86e-06200148748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYH10 FAT3 ITGA2 ABCA6 SCN7A SNAP25 EPB41L2

4.86e-062001487a510deaada669e690329183e18df02870bd204b3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYH10 FAT3 TRPC4 ITGA2 INPP4B ABCA6 SCN7A

4.86e-06200148734f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

BDP1 FAT3 PCLO NACA ACOT7 TTLL7 AKAP9

4.86e-0620014876bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

BDP1 FAT3 PCLO NACA ACOT7 TTLL7 AKAP9

4.86e-062001487c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH10 FAT3 ITGA2 ABCA6 SCN7A SNAP25 EPB41L2

4.86e-062001487dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACOT7 TNFRSF21 TTLL7 SLC8A3 SCN7A PLD1

1.54e-051591486ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACOT7 TNFRSF21 TTLL7 SLC8A3 SCN7A PLD1

1.54e-0515914867b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BLOC1S4 TRPC4 PYROXD2 POSTN KCNQ5 SNAP25

1.72e-051621486502ed67f6a572f10ac6e22948a1747d8214eb974
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BLOC1S4 TRPC4 PYROXD2 POSTN KCNQ5 SNAP25

1.72e-05162148682e782096f89cd03d1fdf599ba727d6f23e35e2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BLOC1S4 TRPC4 PYROXD2 POSTN KCNQ5 SNAP25

1.72e-0516214866bed33b17b59812646dc6a29c1d87413bad86c11
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

AZIN2 INPP4B TTLL7 SNED1 DES SCN7A

1.90e-0516514863d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PALD1 AZIN2 TNFRSF21 ABCA6 SCARB2 KIF17

1.97e-0516614869fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC170 ICOSLG ANXA1 PYROXD2 DES

2.01e-0599148598c40a27432929434879c9e7283a14102f405f39
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC170 ICOSLG ANXA1 PYROXD2 DES

2.01e-05991485d6bd8075dc7aba2034ea78b1389868282bc80a2d
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

PALD1 FAT3 ADCY6 SLC8A3 NYNRIN TRPM8

2.04e-051671486cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN4 TRPC4 INPP4B POSTN KCNQ5 EPB41L2

2.41e-05172148608a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN4 TRPC4 INPP4B POSTN KCNQ5 EPB41L2

2.41e-051721486553701349444eb366df3c11f54bb093434f153c6
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

MYH10 ANXA1 CUL9 SNED1 PCSK6 CPNE7

2.41e-051721486644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ETNPPL ITGA2 TTLL7 TMEM132D KANK4 ARHGEF26

2.65e-0517514869a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SEPTIN4 ACOT7 ZP3 CNNM4 FBXL16 CPNE7

2.74e-051761486bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PALD1 MCM2 INPP4B PCSK6 OSBPL10 ECE2

2.74e-051761486a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 POSTN SNED1 SCN7A KANK4 ARHGEF26

3.01e-051791486c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2 INPP4B SCML4 ALKBH8 SCN7A TUBE1

3.11e-05180148687347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 SH3GL2 DNAH7 SNED1 KCNQ5 EPB41L2

3.30e-05182148614a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellhematopoetic_progenitors-CD34+_MEP_2|World / Lineage and Cell class

RNF130 ANXA1 TTLL7 SND1 MYL6B PLD1

3.30e-051821486a7e7aa10f14111a6c7ba22e0f1668dcaa124714d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC170 SEPTIN4 TRPC4 INPP4B ABCA6 EPB41L2

3.51e-051841486c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 TTLL7 POSTN DES KCNQ5

3.62e-051851486b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 TTLL7 POSTN DES KCNQ5

3.73e-051861486db9b67066fc003c7995ec205d15176bf40c97add
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 TNFRSF21 ADCY6 INPP4B POSTN DES

3.84e-051871486a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 TNFRSF21 ADCY6 INPP4B POSTN DES

3.84e-051871486c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

MYH10 INPP4B TTLL7 POSTN DES PRKD1

3.84e-051871486464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

MYH10 FAT3 TRPC4 ABCA6 SCN7A PRKD1

3.84e-05187148692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IFT57 TMEM132D PTPRQ RASEF ATP11A ARHGEF26

3.96e-051881486eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

3.96e-051881486a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.08e-05189148626cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PALD1 PYROXD2 TNFRSF21 POSTN IGSF22

4.13e-051151485ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PALD1 PYROXD2 TNFRSF21 POSTN IGSF22

4.13e-0511514857a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PALD1 PYROXD2 TNFRSF21 POSTN IGSF22

4.13e-051151485c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.20e-0519014862ab604d35456beba71c25511e0f819000e6642d2
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN4 TNFRSF21 TTLL7 POSTN KCNQ5 EPB41L2

4.20e-0519014867e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYH10 PCLO INPP4B ABCA6 PCSK6 EPB41L2

4.20e-0519014869ce301841ce9486701fa28eb2a9929e35d476878
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 ATRX SEPTIN4 AKAP9 SCN7A EPB41L2

4.20e-051901486d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.20e-051901486951e067d14412db67dc3babcdf61e41717d7b429
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 TRPC4 INPP4B POSTN KANK4 EPB41L2

4.20e-05190148670c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.20e-051901486979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN4 TNFRSF21 TTLL7 POSTN KCNQ5 EPB41L2

4.20e-0519014867fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 SCML4 POSTN DES EPB41L2

4.20e-05190148684fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCellLPS-IL1RA-Endothelial-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF6 PCLO ETNPPL BFSP1 MOV10L1

4.30e-051161485cf4e3c34570f57502ec524881d351ef8e47976d2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 DNAH7 CFAP54 TMEM132D OSBPL10 PRKD1

4.32e-051911486d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 TNFRSF21 ADCY6 POSTN DES VPS51

4.32e-0519114869c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH7 CFAP54 SVIL PDE4DIP ATP11A PRKD1

4.32e-0519114865a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ANKS1B SNED1 ABCA6 PCSK6 SCN7A EPB41L2

4.32e-05191148670c067c54084bfb02c29bab085f4defd477194fb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH7 CFAP54 SVIL PDE4DIP ATP11A PRKD1

4.32e-05191148655ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.32e-0519114862ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH10 FAT3 ITGA2 ABCA6 SCN7A PRKD1

4.32e-0519114866688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 TNFRSF21 ADCY6 POSTN DES VPS51

4.32e-051911486a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

ILF3 POLH AKAP9 BRD4 BOD1L1 CPNE7

4.45e-0519214869cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ANKS1B POSTN SNED1 ABCA6 SCN7A EPB41L2

4.45e-05192148660b1312e84f6d6448365a952469c506c00b5fe93
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEPTIN4 TNFRSF21 POSTN DES KCNQ5 EPB41L2

4.45e-051921486063e119c4b58957643908f667e6cfd6f7517fd03
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MYH10 FAT3 ITGA2 POSTN SCARB2 SCN7A

4.45e-05192148662904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SEPTIN4 FAT3 H6PD SNED1 ARAP1

4.58e-0519314868d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 SEPTIN4 FAT3 H6PD SNED1 ARAP1

4.58e-0519314861b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

POSTN SNED1 ABCA6 SCN7A TLN2 PRKD1

4.58e-051931486e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

PALD1 RNF130 AZIN2 KBTBD8 TNFRSF21 KIF17

4.72e-0519414865f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

AZIN2 ANKS1B SNED1 ABCA6 PCSK6 SCN7A

4.72e-051941486d91c9f2ec47319051fc398320693fddbe8bbd4d6
DiseaseMalignant neoplasm of breast

KIF6 ABCA3 TCP1 POLH TRPC4 KBTBD8 H6PD INPP4B CNNM4 DES RIF1 SLC8A3 ALKBH8 AKAP9 ABCB10 BOD1L1 PRPS1

2.24e-05107414517C0006142
Diseaseperiostin measurement

TRPC4 POSTN

1.43e-0441452EFO_0020628
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1C NCF1B

2.38e-0451452DOID:3265 (implicated_via_orthology)
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

PCLO ANKS1B KDM3B CNNM4 ZCCHC7 ATP2A2

4.79e-042001456EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseasestromal cell-derived factor 1 measurement

ABCA6 ABCA5

4.96e-0471452EFO_0020756
Diseaseperipheral neuropathy

XIRP2 SCN7A

4.96e-0471452EFO_0003100
Diseasebipolar I disorder

ILF3 ANKS1B KDM3B CNNM4 ATP2A2

6.76e-041411455EFO_0009963
Diseaseage at onset, coronary stenosis

PCSK6 PLD1

8.44e-0491452EFO_0004847, MONDO_0006715
Diseasecortical surface area measurement

PALD1 KIF6 MYH10 CNNM2 FAT3 KHNYN SREBF1 CUL9 DNAH7 ARG1 KIAA0825 SND1 PRKAR2A TLN2 PRKD1 TANGO6

9.75e-04134514516EFO_0010736
Diseaseunipolar depression, bipolar disorder

CNNM2 PCLO CNNM4 RPRD2 ZCCHC7

1.06e-031561455EFO_0003761, MONDO_0004985
Diseaseosteoarthritis, hip

RNF130 SHBG TLN2 RPRD2

1.12e-03921454EFO_1000786
DiseaseIschemic stroke

ILF3 KBTBD8 RNF17 TNFRSF21 CCDC83 NYNRIN RASEF

1.14e-033241457HP_0002140
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1C NCF1B

1.53e-03121452DOID:7148 (implicated_via_orthology)
Diseasetype 2 diabetes mellitus (is_implicated_in)

KIF6 SHBG SREBF1 ITGA2 PKLR

1.60e-031711455DOID:9352 (is_implicated_in)
Diseaseschizophrenia, anorexia nervosa

CNNM2 RPRD2 ATP2A2

1.71e-03481453MONDO_0005090, MONDO_0005351
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

STXBP2 KCNQ5

1.81e-03131452DOID:0112202 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

TRPC4 DNAH7 DES BRD4 SVIL TLN2 PLD1 CLEC16A CPNE7 TANGO6

1.81e-0367014510EFO_0006335, EFO_0006336
DiseaseStreptozotocin Diabetes

SREBF1 PKLR SNAP25 ATP2A2

2.02e-031081454C0038433
DiseaseDiabetes Mellitus, Experimental

SREBF1 PKLR SNAP25 ATP2A2

2.02e-031081454C0011853
DiseaseAlloxan Diabetes

SREBF1 PKLR SNAP25 ATP2A2

2.02e-031081454C0002152
DiseaseHamman-Rich syndrome

ABCA3 ATP11A

2.10e-03141452C0085786
Diseasepimelic acid measurement, 3-methyladipic acid measurement

BLOC1S4 KANK4

2.10e-03141452EFO_0010449, EFO_0010524
Diseasebone fracture

CCDC170 PALD1 SHBG SVIL

2.30e-031121454EFO_0003931
Diseaseinterleukin-6 measurement

ANKS1B XIRP2 SCN7A RASEF

2.30e-031121454EFO_0004810
DiseaseColorectal Neoplasms

ABCA3 POSTN ABCB10 ABCA6 ABCA5 PRKD1

2.54e-032771456C0009404
Diseasefourth ventricle volume measurement

XIRP2 SCN7A

2.75e-03161452EFO_0010303
DiseasePontoneocerebellar hypoplasia

EXOSC9 PCLO

2.75e-03161452cv:C1261175
Diseasemigraine without aura, susceptibility to, 4

STXBP2 TRPM8

2.75e-03161452MONDO_0011847
DiseaseAstrocytosis

ITGA2 TNFRSF21

3.11e-03171452C3887640
DiseaseGliosis

ITGA2 TNFRSF21

3.11e-03171452C0017639
Diseasealcohol consumption measurement

MYH10 ANXA1 PCLO ANKS1B SRR INPP4B AKAP9 SND1 PRKAR2A RPRD2 CLEC16A ECE2 SENP7 TANGO6

3.30e-03124214514EFO_0007878
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

ICOSLG ILF3 WDFY4

3.72e-03631453EFO_0000685, EFO_0007791, EFO_0009459
DiseaseCongenital hernia of foramen of Morgagni

DES KCNQ5

3.88e-03191452C0265699
DiseaseCongenital hernia of foramen of Bochdalek

DES KCNQ5

3.88e-03191452C0265700
Diseasesclerosing cholangitis

SGSM1 CLEC16A TANGO6

4.24e-03661453EFO_0004268
Diseaseschizophrenia (implicated_via_orthology)

CNNM2 SRR SNAP25

4.61e-03681453DOID:5419 (implicated_via_orthology)
DiseaseCongenital diaphragmatic hernia

DES KCNQ5

4.74e-03211452C0235833
DiseaseIdiopathic Pulmonary Fibrosis

ABCA3 ATP11A

4.74e-03211452C1800706

Protein segments in the cluster

PeptideGeneStartEntry
DIARISKDMEDSVGL

VANGL1

91

Q8TAA9
ELESTKAVIMGETAV

ABCA5

196

Q8WWZ7
KAVIMGETAVVEIDT

ABCA5

201

Q8WWZ7
ILKMIEEAGAIISTR

ACOT7

76

O00154
ETETLGALREMQDKV

EVI5L

471

Q96CN4
EEVLEKILVSGEMAA

BDP1

831

A6H8Y1
VDEMETDLKTTGREG

BDP1

1166

A6H8Y1
ETLEMGEVVEKDTTE

AKAP9

926

Q99996
ELMIGRKDVISVDAA

CFAP54

471

Q96N23
IDGVLDMRVSKVDTG

CPSF2

631

Q9P2I0
DMRVSKVDTGVILEE

CPSF2

636

Q9P2I0
RMEEQVTKAEAELGT

BLOC1S4

151

Q9NUP1
TEETEIMIVQAKGRG

BRD4

166

O60885
GLMVVEEIISSEEEK

ALKBH8

136

Q96BT7
GVDMIEAISLVREVT

ADCY6

451

O43306
VMVEEGFSTRDLLKE

AZIN2

11

Q96A70
SEMQDLEEIRKITGV

ABCA6

546

Q8N139
GIKVKDDMTEVTGRV

AGO1

396

Q9UL18
TMEEVFLRVGKLVDS

ABCA3

831

Q99758
VRTVRAFGKEMTEIE

ABCB10

361

Q9NRK6
EKVEMLLGAETQSER

ARHGEF26

756

Q96DR7
METKRVEIPGSVLDD

DCP2

1

Q8IU60
RSIEEVEADMKTLGV

CCDC22

346

O60826
TQEMEGIVIVKVEEE

FAM200A

16

Q8TCP9
RILTVLEEAMGTKTE

ETNPPL

431

Q8TBG4
GIIKTVNEDVEEMEI

BAZ1A

1026

Q9NRL2
GLPVVTREDVEEAMK

CCDC83

86

Q8IWF9
TEVDRLGIGKVMEET

ARG1

201

P05089
VDFQMKTLIVDGERT

RASEF

576

Q8IZ41
DIIAVMITELRGKDI

RNF130

151

Q86XS8
LVRDVTEKMDVLGTV

PALD1

101

Q9ULE6
VAVGELTDEDVKMIT

MCM2

451

P49736
MVKGVDEATIIDILT

ANXA1

56

P04083
EEIDKIMSSIDVGIN

ANKS1B

781

Q7Z6G8
ETEETEMKALGERVS

PRKD1

896

Q15139
RNVDLMDIKVGSVEE

MOV10L1

1081

Q9BXT6
TSGILEKSDREVVME

KIAA0825

376

Q8IV33
SGTVSEEIEVLEMVK

JMY

186

Q8N9B5
VGTIEVSVVKMGEIE

INPP4B

176

O15327
TTDDLSMLGRVVKVE

KCNQ5

596

Q9NR82
QEMAEVRKDDVVTVT

FAM185A

341

Q8N0U4
MAGVVVRADILEDKD

HNRNPM

226

P52272
AEVGKDERVITEEMN

EPB41L2

696

O43491
DERVITEEMNGKEIS

EPB41L2

701

O43491
SKEIAEGMISEIRTA

ECE2

501

P0DPD6
IILDGIKMDTGVEVS

EXOSC9

366

Q06265
GTMVTSTEEERKLLD

PCLO

2046

Q9Y6V0
IRMLDGDVTDVVEAK

PCSK6

276

P29122
ALVILAKGAEEMETV

PARK7

6

Q99497
IVMFEGATEEEKLLS

CES5A

471

Q6NT32
NMILGDVEETVTTIE

LSM3

51

P62310
LKDELAMVTGEQRTE

KIF6

371

Q6ZMV9
TRLMEVSVTESGEIK

KDM3B

226

Q7LBC6
KRFDEILEVSDGIMV

PKLR

321

P30613
RRSATKVMVVVTDGE

ITGA2

271

P17301
MALSTGDVVEVVEKS

NCF1B

176

A6NI72
MALSTGDVVEVVEKS

NCF1C

151

A8MVU1
VRIVGVEAESMDLVL

KBTBD8

91

Q8NFY9
VTVFGDIVITKLMED

PTPRQ

2156

Q9UMZ3
QEKEVRAMVGSDVEL

ICOSLG

21

O75144
VESENERAGTVMEEK

BOD1L1

2236

Q8NFC6
TGVNTEIGKIRDEMV

ATP2A2

226

P16615
EIGKIRDEMVATEQE

ATP2A2

231

P16615
AEGTVDKDTTIMELR

ATRX

891

P46100
IVTVEERLATVKSGM

IGSF22

506

Q8N9C0
ETVEMDIRIGIVEHT

IFT57

386

Q9NWB7
SIVTSGMREEKLLTE

BFSP1

201

Q12934
ILTDGVVTDMADTRE

CPNE7

516

Q9UBL6
SEIMIDAEGRIIDVI

DPP8

346

Q6V1X1
VMIKTIETRDGEVVS

DES

446

P17661
HMKSSEGEVVELIEI

DNAH7

1116

Q8WXX0
VMESDRVTEIVGVVS

FAT3

1371

Q8TDW7
VREEMEKVLAGETLS

ILF3

176

Q12906
LTEREKMDTGVVLLS

CCDC144B

186

Q3MJ40
VEVDMRSIGIRVTEE

KANK4

316

Q5T7N3
EVSERMKIVDVIGEK

PRKAR2A

266

P13861
RFMVKLAEETDGIIV

KHNYN

526

O15037
EKALGEISVSVEMAE

CUL9

531

Q8IWT3
TGSTEDTILEKIREM

CCDC170

341

Q8IYT3
LTEREKMDTGVVLLS

CCDC144A

186

A2RUR9
RELLDESQKVMVTVG

HELZ2

1076

Q9BYK8
RVEIIMKETVDAEGR

H6PD

236

O95479
ETVGGDEIVMVIKDS

CASP14

141

P31944
MELSDVEDDGSKIIV

RPRD2

371

Q5VT52
EAASIKEERGDEVMV

MYH10

46

P35580
VVGKRKMIIEDETEF

CMTR1

176

Q8N1G2
TEELMIVLEQGTEVR

PRR23D1

76

E9PI22
RFMVKLAEETDGIIV

NYNRIN

881

Q9P2P1
VKRESVGMEVAVLTD

KIF17

716

Q9P2E2
KRSTITDAGLEVMLE

FBXL16

201

Q8N461
KDIMTEISIISGELE

SENP7

636

Q9BQF6
LGAEERIMQTVEITK

SEPTIN4

176

O43236
VEKIRGLMEDTTQLE

TNFRSF21

491

O75509
KGTSALMTVELDEER

SVIL

1826

O95425
EGQGTLVKVEMVISE

TMEM132D

761

Q14C87
GKRDSEMAVIVQDTE

PLD1

921

Q13393
RMTGEEGKEVITEIE

RIF1

36

Q5UIP0
EVVGKMVSSIIDSLE

RIF1

131

Q5UIP0
KVLEGMEVVRKVEST

PPIB

171

P23284
QVEVKMEGDSVLLEV

SHBG

131

P04278
QREVEVEVESMDKAG

SND1

591

Q7KZF4
KLDDFVETGDIRTMV

SCARB2

391

Q14108
LDKMLVDDIGDVTIT

TCP1

41

P17987
LIGEDKEAGTETVMR

MTRES1

191

Q9P0P8
TVGAVIVEEMRAAIE

POLH

191

Q9Y253
ENVAKRVTEETEGIM

SRR

136

Q9GZT4
MTDLLEEGITVVENI

STXBP3

51

O00186
VKVSAEEAGKTMVRE

URB1

291

O60287
EETELGVMEDQRSII

OSBPL10

386

Q9BXB5
TEELMIVLEQGTEVR

PRR23D2

76

P0DMB1
ALKMERVEESGVSIS

SNED1

911

Q8TER0
VEESKDAGIRTLVML

SNAP25

36

P60880
DVLMEGVKTEVEDTL

SREBF1

411

P36956
SITEETILGAMKDVV

ABCB7

641

O75027
EEITAIVKMRVAGTA

ARAP1

1151

Q96P48
GIKTSGESEEIEMVI

CLEC16A

426

Q2KHT3
QGALELRTKTVEDVM

CNNM2

436

Q9H8M5
MIQGALELRTKTVED

CNNM4

361

Q6P4Q7
LRVGDIVMVKEDETF

ATP11A

146

P98196
AVSMKVFREEDGVLI

RNF17

606

Q9BXT8
ITEIKVVRGISMEEN

XIRP2

611

A4UGR9
AVMKRVVEDTTAIDV

VPS51

611

Q9UID3
SEIGELKQEMVRTDV

RIN2

26

Q8WYP3
EIGNLEKTRSIMAEE

TMF1

1006

P82094
TTLGEKMTEEEVETV

MYL6B

171

P14649
VLEDGTEVRSKMVLS

PYROXD2

326

Q8N2H3
LDDVEGMSVRQLKEI

RNF34

261

Q969K3
SLKARAVLIDMEEGV

TUBE1

66

Q9UJT0
EVGEAMRELSEVKDS

SH3GL2

116

Q99962
GRVRIEKMSSEVVDS

UBA5

36

Q9GZZ9
ILRQLEVAGKEMSEE

STX19

166

Q8N4C7
EVDRMVLVGDVKDRV

PRPS2

201

P11908
KMSDILAEGITIVED

STXBP2

46

Q15833
ERSTEGVDIVMDNLK

WDFY4

1671

Q6ZS81
GIMITIKEAISDEDE

TANGO6

546

Q9C0B7
SVKIMEEKRDESTGV

PRELID2

36

Q8N945
FGMTETERKEVDEQI

SGSM1

636

Q2NKQ1
EGGEIIVTDMDTIEK

UBA1

496

P22314
KSEERSGVIREVMII

ZCCHC7

141

Q8N3Z6
TVMVDDSKTVGELLV

TLN2

101

Q9Y4G6
EVDRMVLVGDVKDRV

PRPS1

201

P60891
RMEKVVSEIESGFLL

SCN7A

1591

Q01118
LTVIKMEEAGDEIVS

TRPM8

391

Q7Z2W7
FVMEESTERKVIKGE

ZNF239

96

Q16600
VLERIMGDKVASEAL

POSTN

286

Q15063
EDKVMTEERGILSGT

ZNF557

91

Q8N988
MQRDKTVVEERVGEE

SMIM45

76

A0A590UK83
LVSMDTEDVVRFEVG

ZP3

81

P21754
EEGRMESVKTVTTEE

SCML4

221

Q8N228
MIRDAKTEEGLTEEN

TRPC4

721

Q9UBN4
AGTKFEIVRLVIDEM

TTLL7

46

Q6ZT98
KIGLRVSIDTDMVEF

ZFYVE16

1476

Q7Z3T8
VSESIGVMEVKVLRT

SLC8A3

541

P57103
ETGVEVKDIELVMSQ

NACA

2036

E9PAV3
VDETGVEVKDIELVM

NACA

171

Q13765
EVMVETVVTKEGLSE

PDE4DIP

1081

Q5VU43