Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microfilament motor activity	MYH10 MYH11 MYH14	9.12e-05	38	46	3	GO:0000146
GeneOntologyBiologicalProcess	muscle tissue development	FLNB MYH10 MYH11 COL11A1 PHOX2B MYH14 RGS4 ZFPM2	2.88e-05	558	46	8	GO:0060537
GeneOntologyCellularComponent	myosin II filament	MYH10 MYH14	1.42e-05	3	46	2	GO:0097513
GeneOntologyCellularComponent	myosin filament	MYH10 MYH11 MYH14	2.22e-05	25	46	3	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH10 MYH11 MYH14	3.14e-05	28	46	3	GO:0016460
GeneOntologyCellularComponent	contractile actin filament bundle	FLNB MYH10 MYH11 MYH14	8.97e-05	107	46	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	FLNB MYH10 MYH11 MYH14	8.97e-05	107	46	4	GO:0001725
GeneOntologyCellularComponent	actomyosin	FLNB MYH10 MYH11 MYH14	1.27e-04	117	46	4	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	FLNB MYH10 MYH11 MYH14	1.31e-04	118	46	4	GO:0032432
GeneOntologyCellularComponent	myosin complex	MYH10 MYH11 MYH14	2.97e-04	59	46	3	GO:0016459
GeneOntologyCellularComponent	post-mRNA release spliceosomal complex	GCFC2 CWF19L1	3.08e-04	12	46	2	GO:0071014
GeneOntologyCellularComponent	brush border	FLNB MYH10 MYH11 MYH14	3.46e-04	152	46	4	GO:0005903
GeneOntologyCellularComponent	cluster of actin-based cell projections	FLNB MYH10 MYH11 MYH14	1.45e-03	223	46	4	GO:0098862
GeneOntologyCellularComponent	supramolecular fiber	DIAPH2 PKP1 KRT72 FLNB MYH10 MYH11 COL11A1 MYH14	3.84e-03	1179	46	8	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	DIAPH2 PKP1 KRT72 FLNB MYH10 MYH11 COL11A1 MYH14	4.00e-03	1187	46	8	GO:0099081
MousePheno	absent coronary vessels	MYH10 ZFPM2	3.64e-05	4	35	2	MP:0010561
Domain	Myosin_N	MYH10 MYH11 MYH14	5.83e-06	15	45	3	PF02736
Domain	Myosin_N	MYH10 MYH11 MYH14	5.83e-06	15	45	3	IPR004009
Domain	Myosin_tail_1	MYH10 MYH11 MYH14	1.04e-05	18	45	3	PF01576
Domain	Myosin_tail	MYH10 MYH11 MYH14	1.04e-05	18	45	3	IPR002928
Domain	Myosin-like_IQ_dom	MYH10 MYH11 MYH14	1.23e-05	19	45	3	IPR027401
Domain	-	MYH10 MYH11 MYH14	1.23e-05	19	45	3	4.10.270.10
Domain	Myosin_S1_N	MYH10 MYH11	5.65e-05	5	45	2	IPR008989
Domain	Myosin_head_motor_dom	MYH10 MYH11 MYH14	1.04e-04	38	45	3	IPR001609
Domain	MYOSIN_MOTOR	MYH10 MYH11 MYH14	1.04e-04	38	45	3	PS51456
Domain	Myosin_head	MYH10 MYH11 MYH14	1.04e-04	38	45	3	PF00063
Domain	MYSc	MYH10 MYH11 MYH14	1.04e-04	38	45	3	SM00242
Domain	IQ	MYH10 MYH11 MYH14	6.66e-04	71	45	3	PF00612
Domain	CarboxyPept-like_regulatory	CPD CILP	7.54e-04	17	45	2	IPR008969
Domain	IQ	MYH10 MYH11 MYH14	9.78e-04	81	45	3	SM00015
Domain	IQ_motif_EF-hand-BS	MYH10 MYH11 MYH14	1.33e-03	90	45	3	IPR000048
Domain	IQ	MYH10 MYH11 MYH14	1.46e-03	93	45	3	PS50096
Domain	-	CTCFL ZNF215 ZNF217 ZIK1 ZNF879 ZFPM2	5.50e-03	679	45	6	3.30.160.60
Domain	zf-C2H2	CTCFL ZNF215 ZNF217 ZIK1 ZNF879 ZFPM2	6.06e-03	693	45	6	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	CTCFL ZNF215 ZNF217 ZIK1 ZNF879 ZFPM2	6.11e-03	694	45	6	IPR013087
Domain	ARM-type_fold	DIAPH2 PKP1 UTP20 DOCK9	8.85e-03	339	45	4	IPR016024
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	MYH10 MYH11 MYH14	1.21e-05	19	34	3	M27493
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	MYH10 MYH11 MYH14	1.21e-05	19	34	3	M27489
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	MYH10 MYH11 MYH14	1.42e-05	20	34	3	M18415
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH10 MYH11 MYH14	1.66e-05	21	34	3	M27494
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH10 MYH11 MYH14	2.20e-05	23	34	3	MM15222
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	MYH10 MYH11 MYH14	2.51e-05	24	34	3	M2243
Pathway	REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE	MYH10 MYH11 MYH14	4.49e-05	29	34	3	M27309
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	MYH10 MYH11 MYH14	4.83e-04	64	34	3	M7923
Pathway	KEGG_VIRAL_MYOCARDITIS	MYH10 MYH11 MYH14	6.28e-04	70	34	3	M12294
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	MYH10 MYH11 MYH14	1.39e-03	92	34	3	M27201
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PKNS	MYH10 MYH11 MYH14	1.43e-03	93	34	3	M27487
Pubmed	A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons.	MYH10 PHOX2B MYH14	4.32e-08	6	46	3	15034141
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	FLNB MYH10 MYH11 MYH14	3.83e-07	45	46	4	22114352
Pubmed	Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.	MYH10 MYH11 MYH14	4.72e-07	12	46	3	8424456
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	BLM SLTM NFXL1 PKP1 UTP20 FLNB POLR1B UBE2M MYH10 CLPX MYH14	1.13e-06	1353	46	11	29467282
Pubmed	Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.	MYH10 MYH11	1.71e-06	2	46	2	16316347
Pubmed	Laminin stimulates and guides axonal outgrowth via growth cone myosin II activity.	MYH10 MYH14	1.71e-06	2	46	2	15880105
Pubmed	Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.	MYH10 MYH11	1.71e-06	2	46	2	10906735
Pubmed	Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition.	MYH10 MYH14	1.71e-06	2	46	2	22025714
Pubmed	Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis.	MYH10 MYH14	1.71e-06	2	46	2	20861308
Pubmed	Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.	MYH10 MYH11	1.71e-06	2	46	2	7916668
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	BLM SLTM ID1 SCAF1 UTP20 FLNB MAGEB2 ZNF217 MYH10	5.02e-06	989	46	9	36424410
Pubmed	Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.	MYH10 MYH11	5.13e-06	3	46	2	16973711
Pubmed	Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.	MYH10 MYH14	5.13e-06	3	46	2	14594953
Pubmed	Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis.	MYH10 MYH14	5.13e-06	3	46	2	15774463
Pubmed	Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II nonmuscle myosin heavy chains.	MYH10 MYH14	5.13e-06	3	46	2	15177565
Pubmed	Characterization of three full-length human nonmuscle myosin II paralogs.	MYH10 MYH14	5.13e-06	3	46	2	24072716
Pubmed	Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II.	MYH10 MYH14	5.13e-06	3	46	2	20685736
Pubmed	Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C.	MYH10 MYH14	5.13e-06	3	46	2	15845534
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	UTP20 FLNB MYH10 MYH11 MYH14	7.10e-06	202	46	5	33005030
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	FLNB UBE2M MYH10 GCFC2 OBI1	9.61e-06	215	46	5	35973513
Pubmed	Cellular nonmuscle myosins NMHC-IIA and NMHC-IIB and vertebrate heart looping.	MYH10 MYH14	1.03e-05	4	46	2	18697221
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SLTM PKP1 SCAF1 UTP20 FLNB UBE2M MYH10 CLPX MYH14 ADGRA3	1.37e-05	1425	46	10	30948266
Pubmed	Human transcription factor protein interaction networks.	BLM UBE2M ZNF217 MYH10 CLPX MYH14 RFXAP ATXN7L1 ATF7IP ZFPM2	1.40e-05	1429	46	10	35140242
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	DIAPH2 FLNB MYH10 MYH11 MYH14	1.48e-05	235	46	5	30258100
Pubmed	Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.	MYH10 MYH14	1.71e-05	5	46	2	19439495
Pubmed	Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development.	MYH10 MYH14	1.71e-05	5	46	2	33871354
Pubmed	Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b.	PHOX2B RGS4	1.71e-05	5	46	2	14627646
Pubmed	Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.	MYH10 MYH14	1.71e-05	5	46	2	25006807
Pubmed	Telokin expression is restricted to smooth muscle tissues during mouse development.	MYH10 MYH11	1.71e-05	5	46	2	11121372
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIAPH2 SLTM NFXL1 CLPX ANKRD50 CWF19L1 PLCE1	2.19e-05	650	46	7	38777146
Pubmed	Nonmuscle myosin II regulation of lung epithelial morphology.	MYH10 MYH14	2.56e-05	6	46	2	22972683
Pubmed	Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice.	MYH10 MYH14	2.56e-05	6	46	2	30044719
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	SLTM UTP20 FLNB POLR1B MYH10 MYH11 MYH14 ADGRA3	3.10e-05	949	46	8	36574265
Pubmed	Nonmuscle myosin II isoform and domain specificity during early mouse development.	MYH10 MYH14	3.58e-05	7	46	2	20679233
Pubmed	SIK2 orchestrates actin-dependent host response upon Salmonella infection.	MYH10 MYH11 MYH14	4.06e-05	50	46	3	33947818
Pubmed	Convergence and extrusion are required for normal fusion of the mammalian secondary palate.	MYH10 MYH14	4.77e-05	8	46	2	25848986
Pubmed	CTCF regulates the local epigenetic state of ribosomal DNA repeats.	POLR1B CTCFL	4.77e-05	8	46	2	21059229
Pubmed	Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.	MYH10 MYH11	4.77e-05	8	46	2	33424621
Pubmed	Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.	MYH10 MYH14	4.77e-05	8	46	2	17429076
Pubmed	Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells.	MYH10 MYH11 MYH14	5.12e-05	54	46	3	22266860
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	SLTM KRT72 FLNB UBE2M MYH10 CAST	7.38e-05	538	46	6	28524877
Pubmed	A point mutation in Myh10 causes major defects in heart development and body wall closure.	MYH10 MYH14	7.65e-05	10	46	2	24825879
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	SLTM UTP20 FLNB POLR1B MYH10	8.55e-05	340	46	5	29478914
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	NFXL1 FLNB UBE2M ZDBF2 TACC1 CAST	9.94e-05	568	46	6	37774976
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNB MYH10 MYH11 MYH14	1.20e-04	191	46	4	33762435
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	BLM NFXL1 PKP1 ID1 UTP20 MYH10 OBI1	1.25e-04	857	46	7	25609649
Pubmed	Genome-wide association study of panic disorder in the Japanese population.	PKP1 SDK2	1.32e-04	13	46	2	19165232
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CPD MYH10 MYH11 MYH14	1.49e-04	202	46	4	24639526
Pubmed	PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.	MYH10 MYH14	1.54e-04	14	46	2	22560610
Pubmed	Patterning and folding of intestinal villi by active mesenchymal dewetting.	MYH10 MYH14	1.78e-04	15	46	2	38781967
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	KRT72 FLNB MYH10 MYH11 MYH14 CAST	2.02e-04	647	46	6	26618866
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	BLM SLTM UTP20 FLNB MYH10 MYH14	2.12e-04	653	46	6	22586326
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB ZDBF2 ZNF217 OBI1 ATF7IP	2.24e-04	418	46	5	34709266
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	KRT72 MYH10 MYH11	2.50e-04	92	46	3	37343697
Pubmed	Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis.	ID1 MYH11	2.58e-04	18	46	2	19619540
Pubmed	SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243.	MYH10 MYH11 MYH14	2.75e-04	95	46	3	33863777
Pubmed	Collagen VI suppresses fibronectin-induced enteric neural crest cell migration by downregulation of focal adhesion proteins.	MYH11 PHOX2B	2.88e-04	19	46	2	29196262
Pubmed	Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.	ID1 MYH11	2.88e-04	19	46	2	22723298
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP31 ANKRD50 ATXN7L1	3.49e-04	103	46	3	10574462
Pubmed	Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons.	MYH10 MYH14	3.54e-04	21	46	2	25168025
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	BLM PKP1 TACC1 ANKRD50 CAST	3.91e-04	472	46	5	38943005
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NFXL1 POLR1B MAGEB2 ZDBF2 TACC1 GCFC2	3.92e-04	733	46	6	34672954
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	MYH10 MYH11 CLPX MYH14	4.24e-04	266	46	4	19380743
Pubmed	Identification of FBXO25-interacting proteins using an integrated proteomics approach.	MYH10 MYH11 MYH14	4.46e-04	112	46	3	20473970
Pubmed	A human MAP kinase interactome.	DIAPH2 MYH10 MYH11 OBI1 ATF7IP	4.46e-04	486	46	5	20936779
Pubmed	A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers.	BLM UBE2M	4.64e-04	24	46	2	16620772
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	BLM FLNB MAGEB2 MYH10 MYH14	4.81e-04	494	46	5	26831064
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNB ANKRD50 MYH14 DOCK9 PLCE1	4.94e-04	497	46	5	23414517
Pubmed	Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.	MYH10 MYH11	5.04e-04	25	46	2	20019329
Pubmed	Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.	ID1 MYH11	5.04e-04	25	46	2	16887829
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SLTM NFXL1 FLNB IRGQ ANKRD50 DOCK9 CAST	5.19e-04	1084	46	7	11544199
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BLM SCAF1 UTP20 ZNF217 GCFC2 CAST	5.23e-04	774	46	6	15302935
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NFXL1 KRT72 FLNB MYH10 MYH11 CLPX MYH14 OBI1	5.48e-04	1442	46	8	35575683
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	BLM UTP20 POLR1B CPD	5.50e-04	285	46	4	32838362
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	FLNB MYH10 MYH11 MYH14	5.72e-04	288	46	4	31501420
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	BLM ZNF217 ATF7IP	6.15e-04	125	46	3	32891193
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	SLTM FLNB MYH10 MYH14	6.25e-04	295	46	4	26209609
Pubmed	Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.	CTCFL ZNF215	6.33e-04	28	46	2	24483146
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SLTM FLNB UBE2M MYH10 MYH11 MYH14	6.51e-04	807	46	6	30575818
Pubmed	HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis.	MYH10 MYH11	6.79e-04	29	46	2	31201155
Pubmed	Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.	MYH10 MYH11	6.79e-04	29	46	2	28049658
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	PKP1 FLNB MYH10 CLPX OBI1	7.86e-04	551	46	5	34728620
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SLTM UTP20 FLNB POLR1B MYH10 MYH14	8.37e-04	847	46	6	35850772
Pubmed	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	ZFPM2 PLCE1	8.80e-04	33	46	2	21658281
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	FLNB MYH10 MYH11 MYH14	9.17e-04	327	46	4	31409639
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	FLNB POLR1B GCFC2 CAST	9.38e-04	329	46	4	17474147
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	FLNB UBE2M MYH10 MYH11 MYH14	9.89e-04	580	46	5	35676659
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BLM ZDBF2 ZNF217 OBI1 ATF7IP	1.05e-03	588	46	5	38580884
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	BLM POLR1B MYH10 MYH11	1.06e-03	340	46	4	24332808
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	NFXL1 PKP1 MYH10 MYH14 CWF19L1	1.16e-03	601	46	5	33658012
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	NFXL1 CTCFL	1.17e-03	38	46	2	28218735
Pubmed	A census of human transcription factors: function, expression and evolution.	NFXL1 ID1 CTCFL ZNF215 PHOX2B ZFPM2	1.20e-03	908	46	6	19274049
Pubmed	Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.	COL11A1 GCFC2	1.23e-03	39	46	2	25859222
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SLTM PKP1 KRT72 UTP20 FLNB POLR1B MYH10	1.24e-03	1257	46	7	36526897
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SLTM SCAF1 SDK2 OBI1	1.32e-03	361	46	4	26167880
Cytoband	4p12	NFXL1 PHOX2B	1.84e-04	20	46	2	4p12
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	SLTM CLPX CILP	3.22e-04	132	46	3	chr15q22
GeneFamily	Myosin heavy chains	MYH10 MYH11 MYH14	2.48e-06	15	33	3	1098
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	CTCFL ZNF215 ZNF217 ZIK1 ZNF879 ZFPM2	1.70e-03	718	33	6	28
Coexpression	IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN	ID1 MYH10 MYH11 RGS4	3.75e-05	107	46	4	M4913
Coexpression	FAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL	ID1 CPD TACC1 IFI6 PLCE1 CAST	4.10e-05	365	46	6	M39018
Coexpression	RIGGINS_TAMOXIFEN_RESISTANCE_DN	SLTM CPD TACC1 ZNF217 IFI6	4.21e-05	221	46	5	M15835
ToppCell	Control-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DIAPH2 ID1 SDK2 DOCK9	2.08e-05	157	46	4	4803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	TACC1 MYH10 MYH11 PLCE1	2.29e-05	161	46	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN6 CILP RGS4 PLCE1	2.52e-05	165	46	4	b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN6 CILP RGS4 PLCE1	2.52e-05	165	46	4	28f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKP1 TACC1 MYH11 PLCE1	2.65e-05	167	46	4	7cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKP1 TACC1 MYH11 PLCE1	2.65e-05	167	46	4	bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKP1 TACC1 MYH11 PLCE1	2.65e-05	167	46	4	e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCell	CTRL-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	FLNB SDK2 ANKRD50 ADGRA3	3.11e-05	174	46	4	ff4315e9fad198cc323fc987deb8652da137cf98
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 SDK2 ZIK1 ZNF879	3.39e-05	178	46	4	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 SDK2 ZIK1 ZNF879	3.39e-05	178	46	4	6178706db4a855d72abc156537604d575624df56
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ID1 FLNB TACC1 DOCK9	3.47e-05	179	46	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ID1 TACC1 IFI6 DOCK9	3.78e-05	183	46	4	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ID1 TACC1 IFI6 DOCK9	3.78e-05	183	46	4	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CCN6 COL11A1 SDK2 ADGRA3	3.95e-05	185	46	4	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CCN6 COL11A1 SDK2 ADGRA3	3.95e-05	185	46	4	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ID1 FLNB ZDBF2 DOCK9	4.03e-05	186	46	4	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	ID1 FLNB TACC1 DOCK9	4.11e-05	187	46	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.11e-05	187	46	4	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	E17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYH10 MYH11 RGS4 PLCE1	4.11e-05	187	46	4	0dee138738b65531ff134a125b92234b5d0a653c
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	CCN6 COL11A1 SDK2 ADGRA3	4.20e-05	188	46	4	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.29e-05	189	46	4	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.29e-05	189	46	4	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	PKP1 ID1 USP31 SDK2	4.38e-05	190	46	4	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	PKP1 ID1 USP31 SDK2	4.38e-05	190	46	4	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.47e-05	191	46	4	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	FLNB CPD ANKRD50 DOCK9	4.56e-05	192	46	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.56e-05	192	46	4	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	PKP1 ID1 USP31 SDK2	4.56e-05	192	46	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.65e-05	193	46	4	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN6 CILP RGS4 PLCE1	4.65e-05	193	46	4	f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN6 CILP RGS4 PLCE1	4.65e-05	193	46	4	4ccf984baebbb13ae916727137ce593fda7514a2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 MYH11 ZFPM2 PLCE1	4.75e-05	194	46	4	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.75e-05	194	46	4	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 MYH11 ZFPM2 PLCE1	4.75e-05	194	46	4	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.75e-05	194	46	4	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	4.84e-05	195	46	4	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKP1 USP31 MYH11 COL11A1	4.94e-05	196	46	4	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ID1 TACC1 IFI6 DOCK9	5.04e-05	197	46	4	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	ID1 FLNB TACC1 DOCK9	5.04e-05	197	46	4	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	USP31 TACC1 MYH11 COL11A1	5.04e-05	197	46	4	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ID1 CPD IFI6 DOCK9	5.04e-05	197	46	4	e567f91fa398fd306d025dcfe89bd50a60216537
ToppCell	Sepsis-Int-URO-Others-RBC\|Int-URO / Disease, condition lineage and cell class	FLNB MYH11 SDK2 GCFC2	5.14e-05	198	46	4	29203aaa5c1844f72289e03f585cd5e7fc498a9a
ToppCell	Sepsis-Int-URO-Others\|Int-URO / Disease, condition lineage and cell class	FLNB MYH11 SDK2 GCFC2	5.14e-05	198	46	4	67f721ea8e60042317ba12efd584f56b07cfb29d
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ID1 TACC1 IFI6 DOCK9	5.14e-05	198	46	4	58508a8df2714d769f137794c29441a7bd38b350
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ID1 TACC1 IFI6 DOCK9	5.14e-05	198	46	4	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCN6 COL11A1 ZFPM2 PLCE1	5.24e-05	199	46	4	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCN6 COL11A1 ZFPM2 PLCE1	5.24e-05	199	46	4	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	distal-2-Endothelial-Artery\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ID1 FLNB TACC1 DOCK9	5.24e-05	199	46	4	fa8aaf7a90699e41a7a4cee5614f8c9248110327
ToppCell	distal-Endothelial-Artery-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ID1 FLNB TACC1 DOCK9	5.24e-05	199	46	4	3788f3218356aaaa10684e48d63757037f8a3a3c
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 SDK2 ADGRA3 ZFPM2	5.34e-05	200	46	4	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ID1 FLNB IFI6 DOCK9	5.34e-05	200	46	4	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	BLM ZNF217 COL11A1 CAST	5.34e-05	200	46	4	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 SDK2 ADGRA3 ZFPM2	5.34e-05	200	46	4	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	BLM ZNF217 COL11A1 CAST	5.34e-05	200	46	4	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ID1 FLNB TACC1 DOCK9	5.34e-05	200	46	4	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SDK2 RGS4 ZFPM2	3.27e-04	130	46	3	05d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCell	LA-10._Endothelium_II\|LA / Chamber and Cluster_Paper	ID1 TACC1 DOCK9	3.57e-04	134	46	3	048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCell	356C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DIAPH2 NFXL1 ANKRD50	3.73e-04	136	46	3	edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell	356C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DIAPH2 NFXL1 ANKRD50	3.73e-04	136	46	3	03e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	USP31 ZNF217 RFXAP	3.97e-04	139	46	3	7c02caed5b9baf233bd6fb9a453708b3e157c790
ToppCell	(08)_PNEC-(2)_48hpi\|(08)_PNEC / shred by cell type and Timepoint	CTCFL ZNF879 CAST	4.23e-04	142	46	3	e95d34170f5053678e0dd9793e68d93c03b05822
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	TACC1 COL11A1 PLCE1	5.06e-04	151	46	3	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UBE2M ZNF215 ZFPM2	5.26e-04	153	46	3	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZIK1 CILP ZFPM2	5.36e-04	154	46	3	511923b27469ea20f8bd82a9ec27119a6e884644
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL11A1 ZFPM2 PLCE1	5.56e-04	156	46	3	abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 CILP ZFPM2	5.56e-04	156	46	3	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 CILP ZFPM2	5.56e-04	156	46	3	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	BLM MAGEB2 COL11A1	5.56e-04	156	46	3	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL11A1 ZFPM2 PLCE1	5.56e-04	156	46	3	dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	KRT72 ATF7IP DOCK9	5.56e-04	156	46	3	1545169694f686d28648a68b552c2ae606599d66
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL11A1 SDK2 CWF19L1	5.67e-04	157	46	3	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	Influenza_Severe-CD4+_T_naive\|Influenza_Severe / Disease group and Cell class	KRT72 DOCK9 ADGRA3	5.67e-04	157	46	3	287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCell	Control-B_naive-12\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DIAPH2 ID1 DOCK9	5.77e-04	158	46	3	41318f864770370ce77ed3fa4a84f76c0c22c482
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PKP1 ID1 DOCK9	6.66e-04	166	46	3	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PKP1 ID1 DOCK9	6.66e-04	166	46	3	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	FLNB SDK2 ANKRD50	6.66e-04	166	46	3	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	Control-Epithelial-Mesothelial\|Control / Disease state, Lineage and Cell class	RGS4 ADGRA3 ZFPM2	6.66e-04	166	46	3	1ed3788257e14f097862b999f020bfe2a57de52b
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	PKP1 DOCK9 ZFPM2	6.78e-04	167	46	3	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 RGS4 PLCE1	6.78e-04	167	46	3	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP RGS4 PLCE1	6.90e-04	168	46	3	e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UTP20 ZIK1 ZNF879	6.90e-04	168	46	3	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP RGS4 PLCE1	6.90e-04	168	46	3	b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KRT72 TACC1 DOCK9	7.02e-04	169	46	3	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL11A1 SDK2 ZFPM2	7.02e-04	169	46	3	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFI6 RFXAP DOCK9	7.02e-04	169	46	3	01a24a8817628125bd004b2be68ffa62c7111f6e
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	TACC1 MYH11 ZFPM2	7.14e-04	170	46	3	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	TACC1 MYH11 ZFPM2	7.14e-04	170	46	3	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	TACC1 MYH11 ZFPM2	7.14e-04	170	46	3	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	T_cells-GNLY+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ID1 MAGEB2 MYH14	7.26e-04	171	46	3	04c811817cfec45af5f2891793106cc7ddb0300e
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKP1 ID1 ZFPM2	7.26e-04	171	46	3	ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	ID1 ZDBF2 ZIK1	7.39e-04	172	46	3	0657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYH10 MYH11 ZFPM2	7.51e-04	173	46	3	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 COL11A1 PLCE1	7.51e-04	173	46	3	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 RGS4 PLCE1	7.51e-04	173	46	3	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 RGS4 PLCE1	7.51e-04	173	46	3	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CTCFL ANKRD50 DOCK9	7.64e-04	174	46	3	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 MYH11 RGS4	7.64e-04	174	46	3	778e0317c0c63fa4efd74114feb760975b819d92
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 RGS4 PLCE1	7.64e-04	174	46	3	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKP1 CWF19L1 PLCE1	7.64e-04	174	46	3	2a96a4fd7d9ef05213b26103c689cf3a26968713
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 RGS4 PLCE1	7.64e-04	174	46	3	197686570cec6d96a92e77e6409325d3bfe6f991
Drug	Simvastatin [79902-63-9]; Up 200; 9.6uM; PC3; HT_HG-U133A	ID1 CILP MYH14 ATXN7L1 DOCK9 ZFPM2	2.35e-06	192	46	6	4244_UP
Disease	INTERVERTEBRAL DISC DISEASE	COL11A1 CILP	2.17e-05	5	44	2	603932
Disease	Lumbar disc disease	COL11A1 CILP	2.17e-05	5	44	2	C0221775
Disease	Intervertebral disc disorder	COL11A1 CILP	2.17e-05	5	44	2	cv:C0158252
Disease	Intervertebral disc disorder	COL11A1 CILP	3.25e-05	6	44	2	C0158252
Disease	low tension glaucoma	FLNB ZFPM2	7.77e-05	9	44	2	EFO_1001022
Disease	aortic measurement	FLNB MYH10 PLCE1 CAST	5.31e-04	251	44	4	EFO_0020865
Disease	panic disorder	PKP1 SDK2	1.11e-03	33	44	2	EFO_0004262
Disease	ascending aortic diameter	FLNB PLCE1 CAST	1.20e-03	140	44	3	EFO_0021787
Disease	response to cytosine arabinoside	CTCFL ZNF215	1.25e-03	35	44	2	EFO_0005655

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEKLASTSCGQKSAG	TACC1	506	O75410
STSCGQKSAGAEVKG	TACC1	511	O75410
EKCGSGEAKSAASGK	CTCFL	566	Q8NI51
SKDGSGDGNKKSASE	CLPX	71	O76031
GDGNKKSASEGSSKK	CLPX	76	O76031
KSASSFKNSSQGCKL	ADGRA3	1101	Q8IWK6
KASKGGKSENSAKSG	ANKRD50	1266	Q9ULJ7
GKSENSAKSGSAGKK	ANKRD50	1271	Q9ULJ7
SAKSGSAGKKAKQSN	ANKRD50	1276	Q9ULJ7
TAKSGGLKNSKHECT	DIAPH2	146	O60879
EGKKRKNSSSSSKAC	ATXN7L1	776	Q9ULK2
SCALKAGKTASGAGE	ID1	16	P41134
AAAAGVSSTKSKKGA	MAGEB2	71	O15479
KVTKTDGCTGKNKAG	NFXL1	681	Q6ZNB6
KGQASSNGCAALKKD	ZFPM2	1016	Q8WW38
NSSGEVDTKKCGSAL	CWF19L1	166	Q69YN2
KTTGFCTNRKNSKGS	COL11A1	56	P12107
DASKVTSKGAGLSKA	FLNB	2511	O75369
CTGESGAGKTENTKK	MYH14	196	Q7Z406
CQTALSADGKGSKGS	OBI1	271	Q5W0B1
SGAKGGKKSDQSNCS	CCN6	166	O95389
VASNCKSGSADSGKL	CEFIP	981	Q711Q0
ASSGSKAKGGSATCR	BLM	1351	P54132
SCDNSSKGSTKKRDV	DOCK9	736	Q9BZ29
SCGNGSSKVKKFDTS	GCFC2	246	P16383
VEAGKKKCSESSDSG	IFI6	21	P09912
DSNNESKKGKGASSS	CPD	876	O75976
CKKAASSSKAPKNGG	CAST	676	P20810
KKAADSTSQCGKATG	ATF7IP	946	Q6VMQ6
AKKTDSGNSAKSGAL	SDK2	1961	Q58EX2
CTGESGAGKTENTKK	MYH10	176	P35580
LSKGREKCSAGSQKA	IRGQ	366	Q8WZA9
TEKSSTGCFSNKSDK	PKP1	506	Q13835
KNKTGSKTQGKSASG	UTP20	1021	O75691
GETASFNKTSGKSSC	PLCE1	1711	Q9P212
SSCGAEKQKGAKSSA	RGS4	181	P49798
EKQKGAKSSADCASL	RGS4	186	P49798
GASGQAKSSSKESKD	SLTM	346	Q9NWH9
KKKSDQALNCGGTAS	RFXAP	176	O00287
CKAQSDAGAVKSKVA	CILP	376	O75339
CTGESGAGKTENTKK	MYH11	176	P35749
SGGQVSLKKSKADSC	SCAF1	936	Q9H7N4
SLKKSKADSCSQAAG	SCAF1	941	Q9H7N4
KADSCSQAAGTKGAE	SCAF1	946	Q9H7N4
SQKSHYKSGECGKAS	ZIK1	206	Q3SY52
AGLKGKSCQSSASAV	ZDBF2	1696	Q9HCK1
KECGKTFKGSSSLNN	ZNF879	291	B4DU55
TSNKCGKAFSKSEDS	ZNF215	436	Q9UL58
TNKGSCAGLSQEKEK	ZNF217	336	O75362
SKKAGGSSVKSVCKN	USP31	1251	Q70CQ4
NIKVCSNDTGSGKFK	POLR1B	851	Q9H9Y6
AAAAAAAKNGSSGKK	PHOX2B	161	Q99453
SAGGTKGSSKKASAA	UBE2M	16	P61081
KTAAADVKTKGSCGS	KRT72	476	Q14CN4