Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF13B MYH3 KIF6 MYH13 SMC3 MYO18B DNAH8

2.44e-061181027GO:0003774
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF13B MYH3 KIF6 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ DNAH8 ATP2B3

1.58e-0544110211GO:0016887
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF13B KRT2 MICAL1 MYH3 KIF6 MYH13 JAKMIP3 CYFIP1 SMC3 XIRP2 SYNE2 CGN NAV3 CDK5RAP2 PAWR ARHGEF2 MYO18B

3.92e-05109910217GO:0008092
GeneOntologyMolecularFunctionATP-dependent activity

KIF13B MYH3 KIF6 MYH13 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ DNAH8 ATP2B3

6.96e-0561410212GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF13B MYH3 KIF6 LSG1 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ RAB32 DNAH8 ATP2B3

1.59e-0477510213GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF13B MYH3 KIF6 LSG1 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ RAB32 DNAH8 ATP2B3

3.43e-0483910213GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF13B MYH3 KIF6 LSG1 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ RAB32 DNAH8 ATP2B3

3.46e-0484010213GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF13B MYH3 KIF6 LSG1 CHD3 CHD4 SMC3 CHD5 NAV3 POLQ RAB32 DNAH8 ATP2B3

3.46e-0484010213GO:0016818
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF13B KIF6 SMC3 DNAH8

4.54e-04701024GO:0003777
GeneOntologyMolecularFunctionactin binding

MICAL1 MYH3 MYH13 CYFIP1 XIRP2 SYNE2 CGN PAWR MYO18B

7.77e-044791029GO:0003779
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD3 CHD4 CHD5

8.86e-04371023GO:0140658
GeneOntologyMolecularFunctionmicrotubule binding

KIF13B KIF6 JAKMIP3 CGN NAV3 CDK5RAP2 ARHGEF2

1.03e-033081027GO:0008017
GeneOntologyMolecularFunctionactin filament binding

MICAL1 MYH3 MYH13 CYFIP1 XIRP2 MYO18B

1.10e-032271026GO:0051015
GeneOntologyMolecularFunctioncalmodulin binding

MYH3 MYH13 RYR1 ASPM CDK5RAP2 ATP2B3

1.17e-032301026GO:0005516
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK11 CYTH2 TIAM2 ARHGEF40 NGEF ARHGEF2

1.20e-032311026GO:0005085
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

ATG2B SYNE2 SUN3

1.57e-03451023GO:0043495
GeneOntologyMolecularFunctiontubulin binding

KIF13B KIF6 JAKMIP3 SMC3 CGN NAV3 CDK5RAP2 ARHGEF2

1.58e-034281028GO:0015631
GeneOntologyBiologicalProcessmicrotubule-based process

KIF13B KIF6 ODAD1 CHD3 CFAP43 CFAP54 AKAP9 SMC3 CEP250 SYNE2 CGN CFAP45 ASPM NAV3 CDK5RAP2 CEP152 CFAP57 ARHGEF2 BSN DNAH8 TUBAL3

8.29e-08105810621GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

ODAD1 CHD3 CFAP43 AKAP9 SMC3 CEP250 SYNE2 CGN ASPM NAV3 CDK5RAP2 CEP152 CFAP57 ARHGEF2 DNAH8 TUBAL3

8.14e-0772010616GO:0000226
GeneOntologyBiologicalProcessorganelle assembly

MYH3 ODAD1 ATG2B CFAP43 STX12 NEK1 CFAP54 SMC3 CEP250 SYNE2 CEP83 ASPM CDK5RAP2 CEP152 CFAP57 ARHGEF2 RAB32 DNAH8

1.87e-05113810618GO:0070925
GeneOntologyBiologicalProcesssupramolecular fiber organization

KRT2 MICAL1 MYH3 EPPK1 PLOD3 KRT80 CYFIP1 AKAP9 XIRP2 NAV3 CDK5RAP2 MYH16 PAWR CGNL1 ARHGEF2 TNXB

2.97e-0595710616GO:0097435
GeneOntologyBiologicalProcesscentrosome localization

AKAP9 SYNE2 CEP83 ASPM

3.05e-05351064GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

AKAP9 SYNE2 CEP83 ASPM

3.42e-05361064GO:0061842
GeneOntologyBiologicalProcessactin filament-based process

MICAL1 MYH3 CACNA2D1 CYTH2 CYFIP1 AKAP9 XIRP2 SYNE2 MYH16 PAWR CGNL1 ARHGEF2 AMOTL2 MYO18B TNXB

6.49e-0591210615GO:0030029
GeneOntologyBiologicalProcesscerebrospinal fluid circulation

CFAP43 CFAP54 CFAP45

1.41e-04201063GO:0090660
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

DOCK11 ODAD1 DEF8 CFAP43 NEK1 CFAP54 CYFIP1 CEP250 SYNE2 CEP83 CFAP57 DNAH8

1.69e-0467010612GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

DOCK11 ODAD1 DEF8 CFAP43 NEK1 CFAP54 CYFIP1 CEP250 SYNE2 CEP83 CFAP57 DNAH8

2.08e-0468510612GO:0030031
GeneOntologyBiologicalProcessmicrotubule-based movement

KIF13B KIF6 ODAD1 CFAP43 CFAP54 SYNE2 CFAP45 CFAP57 BSN DNAH8

2.28e-0449310610GO:0007018
GeneOntologyBiologicalProcessorganelle localization

LSG1 DEF8 STX12 AKAP9 CADPS SYNE2 MAD1L1 CEP83 ASPM CDK5RAP2 ARHGEF2 BSN

2.63e-0470310612GO:0051640
GeneOntologyCellularComponentsupramolecular fiber

KIF13B KRT2 MICAL1 MYH3 KIF6 EPPK1 MYH13 RYR1 KRT80 XIRP2 RTL1 SYNE2 CFAP45 ASPM NAV3 CDK5RAP2 PAWR ARHGEF2 MYO18B DNAH8 TUBAL3

5.58e-07117910821GO:0099512
GeneOntologyCellularComponentmyosin complex

MYH3 MYH13 CGN MYH16 CGNL1 MYO18B

5.96e-07591086GO:0016459
GeneOntologyCellularComponentsupramolecular polymer

KIF13B KRT2 MICAL1 MYH3 KIF6 EPPK1 MYH13 RYR1 KRT80 XIRP2 RTL1 SYNE2 CFAP45 ASPM NAV3 CDK5RAP2 PAWR ARHGEF2 MYO18B DNAH8 TUBAL3

6.23e-07118710821GO:0099081
GeneOntologyCellularComponentpericentriolar material

NEK1 AKAP9 CDK5RAP2 CEP152

1.25e-05281084GO:0000242
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF13B KRT2 MICAL1 KIF6 EPPK1 KRT80 CFAP45 ASPM NAV3 CDK5RAP2 PAWR ARHGEF2 MYO18B DNAH8 TUBAL3

5.92e-0589910815GO:0099513
GeneOntologyCellularComponentbicellular tight junction

EPPK1 CYTH2 CGN CGNL1 ARHGEF2 AMOTL2

6.12e-051311086GO:0005923
GeneOntologyCellularComponentmitotic spindle pole

SMC3 MAD1L1 ASPM CDK5RAP2

7.12e-05431084GO:0097431
GeneOntologyCellularComponenttight junction

EPPK1 CYTH2 CGN CGNL1 ARHGEF2 AMOTL2

8.51e-051391086GO:0070160
GeneOntologyCellularComponentNuRD complex

CHD3 CHD4 CHD5

8.65e-05171083GO:0016581
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA1 MMRN1 TNXB

8.65e-05171083GO:0098637
GeneOntologyCellularComponentCHD-type complex

CHD3 CHD4 CHD5

8.65e-05171083GO:0090545
GeneOntologyCellularComponentapical junction complex

EPPK1 CYTH2 CGN CGNL1 ARHGEF2 AMOTL2

1.72e-041581086GO:0043296
GeneOntologyCellularComponentactin cytoskeleton

MICAL1 MYH3 MYH13 RGS22 XIRP2 CGN MYH16 PAWR CGNL1 ARHGEF2 MYO18B

1.95e-0457610811GO:0015629
GeneOntologyCellularComponent9+2 motile cilium

PCDH11Y CFAP43 AKAP9 CFAP45 PCDH11X CFAP57 DNAH8

2.39e-042381087GO:0097729
GeneOntologyCellularComponentmyosin filament

MYH3 MYH13 MYO18B

2.84e-04251083GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH3 MYH13 MYO18B

4.00e-04281083GO:0016460
GeneOntologyCellularComponentmyofibril

MYH3 MYH13 RYR1 XIRP2 RTL1 SYNE2 MYO18B

5.45e-042731087GO:0030016
GeneOntologyCellularComponentcentrosome

SCYL1 CHD3 CHD4 NEK1 AKAP9 CEP250 MAD1L1 CEP83 ASPM CDK5RAP2 CEP152 RAB11FIP4

6.28e-0477010812GO:0005813
GeneOntologyCellularComponentcontractile muscle fiber

MYH3 MYH13 RYR1 XIRP2 RTL1 SYNE2 MYO18B

7.77e-042901087GO:0043292
GeneOntologyCellularComponentmicrotubule end

ASPM NAV3 CDK5RAP2

9.92e-04381083GO:1990752
GeneOntologyCellularComponentsarcoplasmic reticulum

CACNA2D1 RYR1 SYNE2 SRL

1.13e-03881084GO:0016529
GeneOntologyCellularComponentZ disc

RYR1 XIRP2 RTL1 SYNE2 MYO18B

1.13e-031511085GO:0030018
GeneOntologyCellularComponentdense core granule membrane

VPS13C CADPS

1.16e-03101082GO:0032127
GeneOntologyCellularComponentextrinsic component of membrane

CYTH2 RYR1 ARHGEF40 AKAP9 CADPS BSN

1.25e-032301086GO:0019898
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE2 SUN3

1.41e-03111082GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE2 SUN3

1.41e-03111082GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE2 SUN3

1.41e-03111082GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE2 SUN3

1.41e-03111082GO:0034993
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 SYNE2 SRL

1.63e-03451083GO:0033017
GeneOntologyCellularComponentouter dynein arm

ODAD1 DNAH8

1.69e-03121082GO:0036157
GeneOntologyCellularComponentextrinsic component of postsynaptic specialization membrane

CYTH2 AKAP9

1.69e-03121082GO:0098892
GeneOntologyCellularComponentI band

RYR1 XIRP2 RTL1 SYNE2 MYO18B

1.72e-031661085GO:0031674
GeneOntologyCellularComponentmicrotubule

KIF13B KIF6 CFAP45 ASPM NAV3 CDK5RAP2 ARHGEF2 DNAH8 TUBAL3

1.78e-035331089GO:0005874
GeneOntologyCellularComponentsarcomere

MYH3 RYR1 XIRP2 RTL1 SYNE2 MYO18B

1.87e-032491086GO:0030017
GeneOntologyCellularComponentexcitatory synapse

CHD4 CYFIP1 BSN ATP2B3

2.31e-031071084GO:0060076
GeneOntologyCellularComponentmotile cilium

PCDH11Y CFAP43 AKAP9 CFAP45 PCDH11X CFAP57 DNAH8

2.47e-033551087GO:0031514
GeneOntologyCellularComponentmicrotubule organizing center

SCYL1 CHD3 CHD4 NEK1 AKAP9 CEP250 MAD1L1 CEP83 ASPM CDK5RAP2 CEP152 RAB11FIP4

2.81e-0391910812GO:0005815
GeneOntologyCellularComponentsarcoplasm

CACNA2D1 RYR1 SYNE2 SRL

2.91e-031141084GO:0016528
GeneOntologyCellularComponentmuscle myosin complex

MYH3 MYH13

3.03e-03161082GO:0005859
GeneOntologyCellularComponentdense core granule

CACNA2D1 VPS13C CADPS

3.05e-03561083GO:0031045
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA1 MMRN1 TNXB

3.53e-03591083GO:0098636
GeneOntologyCellularComponentspindle pole

SMC3 CEP250 MAD1L1 ASPM CDK5RAP2

4.26e-032051085GO:0000922
GeneOntologyCellularComponentaxoneme

ODAD1 CFAP43 CFAP54 CFAP45 DNAH8

4.44e-032071085GO:0005930
GeneOntologyCellularComponentciliary plasm

ODAD1 CFAP43 CFAP54 CFAP45 DNAH8

4.53e-032081085GO:0097014
GeneOntologyCellularComponentextrinsic component of postsynaptic membrane

CYTH2 AKAP9

5.71e-03221082GO:0098890
DomainCHDCT2

CHD3 CHD4 CHD5

1.73e-0731053PF08074
DomainCHDNT

CHD3 CHD4 CHD5

1.73e-0731053PF08073
DomainDUF1086

CHD3 CHD4 CHD5

1.73e-0731053IPR009462
DomainDUF1087

CHD3 CHD4 CHD5

1.73e-0731053IPR009463
DomainCHD_N

CHD3 CHD4 CHD5

1.73e-0731053IPR012958
DomainCHD_C2

CHD3 CHD4 CHD5

1.73e-0731053IPR012957
DomainDUF1087

CHD3 CHD4 CHD5

1.73e-0731053PF06465
DomainDUF1086

CHD3 CHD4 CHD5

1.73e-0731053PF06461
DomainDUF1087

CHD3 CHD4 CHD5

1.73e-0731053SM01147
DomainDUF1086

CHD3 CHD4 CHD5

1.73e-0731053SM01146
DomainMyosin_tail_1

MYH3 MYH13 CGN CGNL1

2.72e-06181054PF01576
DomainMyosin_tail

MYH3 MYH13 CGN CGNL1

2.72e-06181054IPR002928
DomainMyosin-like_IQ_dom

MYH3 MYH13 ASPM MYO18B

3.43e-06191054IPR027401
Domain-

MYH3 MYH13 ASPM MYO18B

3.43e-061910544.10.270.10
DomainP-loop_NTPase

KIF13B MYH3 KIF6 MYH13 LSG1 CHD3 CHD4 SMC3 CHD5 ASPM NAV3 SRL MYO18B POLQ RAB32 DNAH8

2.01e-0584810516IPR027417
DomainPH

DOCK11 CYTH2 TIAM2 ARHGEF40 CADPS OSBPL1A NGEF PHLPP1 ARHGEF2

2.72e-052781059SM00233
DomainPH_DOMAIN

DOCK11 CYTH2 TIAM2 ARHGEF40 CADPS OSBPL1A NGEF PHLPP1 ARHGEF2

2.80e-052791059PS50003
DomainPH_domain

DOCK11 CYTH2 TIAM2 ARHGEF40 CADPS OSBPL1A NGEF PHLPP1 ARHGEF2

2.88e-052801059IPR001849
DomainATG_C

VPS13C ATG2B

3.10e-0451052PF09333
DomainProtocadherin

PCDH11Y PCDH11X

3.10e-0451052PF08374
DomainAutophagy-rel_C

VPS13C ATG2B

3.10e-0451052IPR015412
DomainProtocadherin

PCDH11Y PCDH11X

3.10e-0451052IPR013585
DomainPH

DOCK11 CYTH2 TIAM2 CADPS NGEF PHLPP1 ARHGEF2

3.13e-042291057PF00169
DomainChromo_domain

CHD3 CHD4 CHD5

3.21e-04241053IPR023780
DomainRING

KAT6A DEF8 CHD3 CHD4 TRIM22 RNF123 CHD5 TRIM60

3.27e-043051058SM00184
Domain-

DOCK11 CYTH2 TIAM2 ARHGEF40 CADPS OSBPL1A NGEF PHLPP1 ARHGEF2

3.61e-0439110592.30.29.30
DomainChromo

CHD3 CHD4 CHD5

4.09e-04261053PF00385
DomainDH_1

TIAM2 ARHGEF40 NGEF ARHGEF2

4.35e-04631054PS00741
DomainCH

MICAL1 SYNE2 ASPM NAV3

4.91e-04651054SM00033
DomainZnf_RING

KAT6A DEF8 CHD3 CHD4 TRIM22 RNF123 CHD5 TRIM60

5.08e-043261058IPR001841
DomainCHROMO_1

CHD3 CHD4 CHD5

5.11e-04281053PS00598
DomainCHROMO_2

CHD3 CHD4 CHD5

5.11e-04281053PS50013
DomainRhoGEF

TIAM2 ARHGEF40 NGEF ARHGEF2

6.50e-04701054PF00621
DomainCH

MICAL1 SYNE2 ASPM NAV3

6.50e-04701054PF00307
DomainDH_2

TIAM2 ARHGEF40 NGEF ARHGEF2

6.50e-04701054PS50010
DomainPH_dom-like

DOCK11 CYTH2 TIAM2 ARHGEF40 CADPS OSBPL1A NGEF PHLPP1 ARHGEF2

6.69e-044261059IPR011993
DomainIQ

MYH3 MYH13 ASPM MYO18B

6.86e-04711054PF00612
DomainDH-domain

TIAM2 ARHGEF40 NGEF ARHGEF2

6.86e-04711054IPR000219
Domain-

TIAM2 ARHGEF40 NGEF ARHGEF2

6.86e-047110541.20.900.10
Domain-

MICAL1 SYNE2 ASPM NAV3

6.86e-047110541.10.418.10
DomainSNF2_N

CHD3 CHD4 CHD5

7.61e-04321053IPR000330
DomainChromodomain-like

CHD3 CHD4 CHD5

7.61e-04321053IPR016197
DomainSNF2_N

CHD3 CHD4 CHD5

7.61e-04321053PF00176
DomainCH

MICAL1 SYNE2 ASPM NAV3

7.62e-04731054PS50021
DomainChromo/shadow_dom

CHD3 CHD4 CHD5

8.33e-04331053IPR000953
DomainCHROMO

CHD3 CHD4 CHD5

8.33e-04331053SM00298
DomainPHD

KAT6A CHD3 CHD4 CHD5

8.44e-04751054PF00628
DomainCH-domain

MICAL1 SYNE2 ASPM NAV3

8.44e-04751054IPR001715
DomainVPS13_N

VPS13C ATG2B

8.57e-0481052IPR026854
DomainChorein_N

VPS13C ATG2B

8.57e-0481052PF12624
DomainDNA/RNA_helicase_DEAH_CS

CHD3 CHD4 CHD5

9.91e-04351053IPR002464
DomainZnf_PHD-finger

KAT6A CHD3 CHD4 CHD5

1.03e-03791054IPR019787
DomainIQ

MYH3 MYH13 ASPM MYO18B

1.13e-03811054SM00015
DomainDEAH_ATP_HELICASE

CHD3 CHD4 CHD5

1.26e-03381053PS00690
DomainMyosin_head_motor_dom

MYH3 MYH13 MYO18B

1.26e-03381053IPR001609
DomainMYOSIN_MOTOR

MYH3 MYH13 MYO18B

1.26e-03381053PS51456
DomainMyosin_head

MYH3 MYH13 MYO18B

1.26e-03381053PF00063
DomainMYSc

MYH3 MYH13 MYO18B

1.26e-03381053SM00242
DomainGDS_CDC24_CS

TIAM2 NGEF ARHGEF2

1.36e-03391053IPR001331
DomainZnf_FYVE_PHD

KAT6A CHD3 CHD4 CHD5 BSN

1.45e-031471055IPR011011
DomainSPRY

TRIM22 RYR1 RNF123 TRIM60

1.47e-03871054SM00449
DomainConA-like_dom

LAMA1 TRIM22 RYR1 MMRN1 RNF123 TRIM60

1.49e-032191056IPR013320
DomainPHD

KAT6A CHD3 CHD4 CHD5

1.60e-03891054SM00249
DomainIQ_motif_EF-hand-BS

MYH3 MYH13 ASPM MYO18B

1.66e-03901054IPR000048
DomainZnf_PHD

KAT6A CHD3 CHD4 CHD5

1.73e-03911054IPR001965
Domaint-SNARE

STX12 CDK5RAP2 AMOTL2

1.81e-03431053IPR010989
DomainIQ

MYH3 MYH13 ASPM MYO18B

1.88e-03931054PS50096
DomainSPRY

TRIM22 RYR1 RNF123 TRIM60

1.95e-03941054PF00622
DomainSPRY_dom

TRIM22 RYR1 RNF123 TRIM60

1.95e-03941054IPR003877
DomainB30.2/SPRY

TRIM22 RYR1 RNF123 TRIM60

2.03e-03951054IPR001870
DomainB302_SPRY

TRIM22 RYR1 RNF123 TRIM60

2.03e-03951054PS50188
DomainZF_PHD_2

KAT6A CHD3 CHD4 CHD5

2.03e-03951054PS50016
DomainZF_PHD_1

KAT6A CHD3 CHD4 CHD5

2.11e-03961054PS01359
DomainHelicase_C

CHD3 CHD4 CHD5 POLQ

3.12e-031071054PF00271
DomainHELICc

CHD3 CHD4 CHD5 POLQ

3.12e-031071054SM00490
DomainMyosin_N

MYH3 MYH13

3.13e-03151052PF02736
DomainMyosin_N

MYH3 MYH13

3.13e-03151052IPR004009
DomainHelicase_C

CHD3 CHD4 CHD5 POLQ

3.23e-031081054IPR001650
DomainHELICASE_CTER

CHD3 CHD4 CHD5 POLQ

3.34e-031091054PS51194
DomainHELICASE_ATP_BIND_1

CHD3 CHD4 CHD5 POLQ

3.34e-031091054PS51192
DomainDEXDc

CHD3 CHD4 CHD5 POLQ

3.34e-031091054SM00487
DomainHelicase_ATP-bd

CHD3 CHD4 CHD5 POLQ

3.45e-031101054IPR014001
DomainLaminin_N

LAMB4 LAMA1

3.57e-03161052IPR008211
DomainLAMININ_NTER

LAMB4 LAMA1

3.57e-03161052PS51117
DomainLaminin_N

LAMB4 LAMA1

3.57e-03161052PF00055
DomainLamNT

LAMB4 LAMA1

3.57e-03161052SM00136
Domain-

KAT6A CHD3 CHD4 TRIM22 RNF123 CHD5 BSN TRIM60

3.83e-0344910583.30.40.10
DomainZnf_RING/FYVE/PHD

KAT6A CHD3 CHD4 TRIM22 RNF123 CHD5 BSN TRIM60

4.37e-034591058IPR013083
DomainFibrinogen_CS

ANGPTL1 TNXB

5.03e-03191052IPR020837
PathwayREACTOME_MITOTIC_PROMETAPHASE

AKAP9 SMC3 CEP250 MAD1L1 CDK5RAP2 CEP152 TUBAL3

1.15e-04202777MM15362
PathwayREACTOME_MITOTIC_PROMETAPHASE

AKAP9 SMC3 CEP250 MAD1L1 CDK5RAP2 CEP152 TUBAL3

1.22e-04204777M4217
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

AKAP9 CEP250 CDK5RAP2 CEP152 TUBAL3

1.30e-0490775MM14979
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

AKAP9 CEP250 CDK5RAP2 CEP152 TUBAL3

1.68e-0495775M6729
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

AKAP9 CEP250 CEP83 CDK5RAP2 CEP152

1.77e-0496775MM15207
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

AKAP9 CEP250 CEP83 CDK5RAP2 CEP152

1.86e-0497775M27478
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

TIAM2 ARHGEF40 NGEF ARHGEF2

2.98e-0459774M11215
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

KAT6A CHD3 CHD4

5.17e-0429773MM15340
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

KAT6A CHD3 CHD4

5.72e-0430773M27637
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

AKAP9 CEP250 CDK5RAP2 CEP152

6.06e-0471774MM15495
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

AKAP9 CEP250 CDK5RAP2 CEP152

6.39e-0472774M27749
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

TIAM2 ARHGEF40 NGEF ARHGEF2

7.84e-0476774M19832
PathwayREACTOME_CILIUM_ASSEMBLY

AKAP9 CEP250 CEP83 CDK5RAP2 CEP152 TUBAL3

7.98e-04201776M27472
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

TIAM2 ARHGEF40 NGEF ARHGEF2

9.50e-0480774M800
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

AKAP9 CEP250 CDK5RAP2 CEP152

9.96e-0481774M748
PathwayPID_RAC1_REG_PATHWAY

TIAM2 NGEF ARHGEF2

1.15e-0338773M241
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

AKAP9 CEP250 CEP83 CDK5RAP2 CEP152 TUBAL3

1.19e-03217776MM14708
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

AKAP9 CEP250 CDK5RAP2 CEP152

1.19e-0385774MM14906
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

AKAP9 CEP250 CDK5RAP2 CEP152

1.30e-0387774M27194
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF13B CACNA2D1 DOCK11 LSG1 CYTH2 CHD4 JAKMIP3 CYFIP1 AKAP9 RABEP1 SYNE2 MAD1L1 NGEF CDK5RAP2 ARHGEF2 BSN CUX1

7.47e-099631081728671696
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KIF13B KRT2 MYH3 MYH13 LSG1 CHD3 CHD4 AHCYL2 CHD5 SYNE2 CEP83 CFAP45 ASPM ARHGEF2 BSN POLQ DNAH8 ATP2B3 CUX1

9.50e-0814421081935575683
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD3 CHD4 CHD5 CUX1

2.03e-0717108427806305
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIF13B DOCK11 LSG1 FRYL NEK1 AKAP9 RABEP1 SYNE2 CGN MAD1L1 CEP152 CGNL1 ARHGEF2 TSC22D4

4.75e-078611081436931259
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

CHD4 AKAP9 CEP250 SYNE2 CDK5RAP2 CUX1

7.77e-07101108626949739
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH3 PLOD3 MYH13 SCYL1 CHD4 NEK1 TAOK3 ARHGEF40 CYFIP1 AKAP9 RTL1 CDK5RAP2 ARHGEF2 TUBAL3

9.15e-079101081436736316
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

LSG1 UPF2 RABEP1 SYNE2 CEP83 CDK5RAP2 CEP152 ARHGEF2

1.24e-06251108829778605
Pubmed

VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.

ASPM CDK5RAP2 CEP152 CUX1

1.46e-0627108421737879
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

KRT2 IARS1 CHD3 CHD4 ARHGEF40 UPF2 ATP2B3

3.41e-06202108724639526
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH3 CHD4 RYR1 AKAP9 UPF2 XIRP2 RABEP1 SYNE2 CDK5RAP2 MYO18B

3.60e-064971081023414517
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

EPPK1 LAMA1 RYR1 CGN CDK5RAP2 BSN POLQ

4.14e-06208108733230847
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

USP24 REV3L RYR1 RNF123 CYFIP1 SYNE2 CDK5RAP2 ARHGEF2 BSN ATP2B3 CUX1

5.02e-066381081131182584
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

MYH13 PCDH11Y SLC30A1 TRIM22 XIRP2 PCDH11X BSN

8.69e-06233108737704626
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

9.55e-06210827560064
Pubmed

The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.

PCDH11Y PCDH11X

9.55e-062108223600975
Pubmed

A comparative analysis of the pig, mouse, and human PCDHX genes.

PCDH11Y PCDH11X

9.55e-062108215112107
Pubmed

Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.

PCDH11Y PCDH11X

9.55e-062108222744706
Pubmed

Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.

PCDH11Y PCDH11X

9.55e-062108211003707
Pubmed

Pcdh11x Negatively Regulates Dendritic Branching.

PCDH11Y PCDH11X

9.55e-062108225687328
Pubmed

Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain.

REV3L POLQ

9.55e-062108232838755
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

9.55e-06210827575689
Pubmed

JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.

CGN CGNL1

9.55e-062108215292197
Pubmed

A Novel Mutation in Isoform 3 of the Plasma Membrane Ca2+ Pump Impairs Cellular Ca2+ Homeostasis in a Patient with Cerebellar Ataxia and Laminin Subunit 1α Mutations.

LAMA1 ATP2B3

9.55e-062108225953895
Pubmed

Quantitative analysis of alternative transcripts of human PCDH11X/Y genes.

PCDH11Y PCDH11X

9.55e-062108219859901
Pubmed

Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition.

CGN ARHGEF2

9.55e-062108215866167
Pubmed

Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.

PCDH11Y PCDH11X

9.55e-062108222592879
Pubmed

Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.

PCDH11Y PCDH11X

9.55e-062108214727141
Pubmed

Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.

PCDH11Y PCDH11X

9.55e-062108221276771
Pubmed

Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development.

CHD3 CHD4

9.55e-062108235568926
Pubmed

Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2.

ASPM CDK5RAP2

9.55e-062108228883092
Pubmed

Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells.

CGN ARHGEF2

9.55e-062108234345888
Pubmed

Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen.

CHD3 CHD4

9.55e-06210828843877
Pubmed

Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.

PCDH11Y PCDH11X

9.55e-062108216874762
Pubmed

PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.

PCDH11Y PCDH11X

9.55e-062108216825765
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

VPS39 DEF8 CHD4 JAKMIP3 REV3L RNF123 CADPS RABEP1 OSBPL1A NGEF NAV3 RAB11FIP4 AMOTL2 MVP CUX1

1.05e-0512851081535914814
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DOCK11 FRYL AKAP9 SMC3 RABEP1 CGN CEP152 ARHGEF2 AMOTL2

1.10e-05446108924255178
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD3 CHD4 CHD5

1.29e-0515108335695185
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ASPM CDK5RAP2 CEP152

1.58e-0516108320301772
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH3 LAMB4 DOCK11 IARS1 VPS13C LAMA1 REV3L RYR1 RNF123 CFAP57 AMOTL2

1.90e-057361081129676528
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

RGS22 PCDH11Y TLR9 SYNE2 PCDH11X MVP TRIM60

2.65e-05277108730745168
Pubmed

Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).

PCDH11Y PCDH11X

2.86e-053108219125366
Pubmed

The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.

CHD3 CHD4

2.86e-053108232658897
Pubmed

MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly.

CGN CGNL1

2.86e-053108224807907
Pubmed

Non-clustered protocadherin.

PCDH11Y PCDH11X

2.86e-053108221173574
Pubmed

Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.

PCDH11Y PCDH11X

2.86e-053108221129452
Pubmed

Genetic heterogeneity in Pakistani microcephaly families revisited.

ASPM CDK5RAP2

2.86e-053108228004384
Pubmed

The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.

AKAP9 CDK5RAP2

2.86e-053108229054927
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

KRT2 MYH13 LSG1 C9orf78 VPS13C SCYL1 CHD4 SLC30A1 CDK5RAP2 CGNL1 CUX1

3.12e-057771081135844135
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT2 EPPK1 PLOD3 LSG1 IARS1 KRT80 CYFIP1 UPF2 SMC3 CHD5 CGN PAWR ARHGEF2 MVP

3.56e-0512571081436526897
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

KIF13B REV3L CYFIP1 SMC3 SYNE2 ATP2B3

3.62e-05197108620811636
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KRT2 MICAL1 CACNA2D1 IARS1 CYTH2 CHD3 CYFIP1 UPF2 CADPS NGEF CGNL1 ARHGEF2 TSC22D4 BSN ATP2B3

3.67e-0514311081537142655
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPPK1 PLOD3 VPS39 KAT6A FRYL CFAP43 REV3L RYR1 TIAM2 ARHGEF40 CHD5 MAD1L1 ARHGEF2

3.96e-0511051081335748872
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SAMD1 ATG2B USP24 CHD3 CHD4 NEK1 RABEP1 CUX1

5.03e-05418108834709266
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

VPS39 FRYL CHD4 SMC3 ARHGEF2

5.33e-05129108523022380
Pubmed

Characterization of the CHD family of proteins.

CHD3 CHD4

5.71e-05410829326634
Pubmed

Microcephaly genes and risk of late-onset Alzheimer disease.

ASPM CDK5RAP2

5.71e-054108221297427
Pubmed

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13.

STX12 RABEP1

5.71e-054108210458612
Pubmed

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.

PLOD3 LAMA1

5.71e-054108216467571
Pubmed

The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.

CYTH2 CUX1

5.71e-054108212052827
Pubmed

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

TIAM2 SYNE2

5.71e-054108229844364
Pubmed

The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis.

VPS39 STX12

5.71e-054108211936273
Pubmed

Sex-dependent association of common variants of microcephaly genes with brain structure.

ASPM CDK5RAP2

5.71e-054108220080800
Pubmed

NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.

CHD3 CHD4

5.71e-054108216574654
Pubmed

The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling.

CACNA2D1 RYR1

5.71e-054108215536090
Pubmed

A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2.

REV3L MAD1L1

5.71e-054108210660610
Pubmed

Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.

CACNA2D1 OSBPL1A NGEF CUX1

6.51e-0569108415142957
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MYH3 CACNA2D1 PLOD3 MYH13 VPS13C SLC26A4 RYR1 TIAM2 CEP250 OSBPL1A CDK5RAP2 MVP

7.71e-0510161081219056867
Pubmed

Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.

RYR1 MYO18B CUX1

8.07e-0527108337995181
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

EPPK1 IARS1 KAT6A CHD3 CHD4 ARHGEF2 AMOTL2

8.29e-05332108737433992
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYH13 LAMA1 CEP250 NGEF ASPM CGNL1

9.40e-05234108636243803
Pubmed

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.

CEP250 CEP152

9.50e-055108226337392
Pubmed

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly.

AKAP9 CDK5RAP2

9.50e-055108225657325
Pubmed

Centaurin-alpha1 interacts directly with kinesin motor protein KIF13B.

KIF13B CYTH2

9.50e-055108215923660
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

NEK1 AKAP9 CEP250 CDK5RAP2 CEP152

9.58e-05146108521399614
Pubmed

Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex.

CACNA2D1 CHD4 CUX1

1.11e-0430108318055048
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

VPS13C UPF2 CHD5 CGN PCDH11X

1.19e-04153108510718198
Pubmed

Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.

MYH3 LAMA1 MYO18B

1.23e-0431108322282597
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

KRT2 EPPK1 PLOD3 LSG1 C9orf78 IARS1 USP24 CHD4 AHCYL2 SLC30A1 CYFIP1 SMC3 SYNE2 ARHGEF2

1.25e-0414151081428515276
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

EPPK1 DOCK11 C9orf78 AHCYL2 TIAM2 ARHGEF40 CYFIP1 SMC3 CGN NGEF ARHGEF2

1.35e-049161081132203420
Pubmed

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex.

AKAP9 CDK5RAP2

1.42e-046108220466722
Pubmed

Protocadherin 11 x regulates differentiation and proliferation of neural stem cell in vitro and in vivo.

PCDH11Y PCDH11X

1.42e-046108224647733
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

MYH3 RYR1

1.42e-046108210444070
Pubmed

Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.

CHD3 CHD4

1.42e-046108217626165
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH3 MYH13

1.42e-046108210077619
Pubmed

Cep44 functions in centrosome cohesion by stabilizing rootletin.

CEP250 CDK5RAP2

1.42e-046108231974111
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

EPPK1 ATG2B CHD3 SLC30A1 ASPM PHLPP1

1.53e-04256108633397691
Pubmed

Identification of substrates of SMURF1 ubiquitin ligase activity utilizing protein microarrays.

C9orf78 SCYL1 TAOK3 RABEP1

1.61e-0487108420804422
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

REV3L RNF123 AKAP9 SMC3

1.61e-0487108417148452
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRYL SYNE2 PHLPP1 ARHGEF2

1.61e-0487108412465718
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

CHD3 CHD4 CHD5

1.77e-0435108327142060
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SAMD1 EPPK1 LSG1 IARS1 CHD4 SMC3 CHD5 PAWR ARHGEF2 MVP TUBAL3

1.83e-049491081136574265
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

MYH3 CACNA2D1 EPPK1 KAT6A SCYL1 CHD4 REV3L RYR1 TIAM2 PUS10 CGN POLQ TNXB

1.90e-0412931081315342556
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

CHD3 CHD4 CHD5 AMOTL2

1.91e-0491108420362542
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

CHD3 RABEP1 SYNE2 MAD1L1 CEP83

1.95e-04170108523314748
Pubmed

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

ARHGEF2 CUX1

1.99e-047108228453519
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH3 MYH13

1.99e-047108235210422
Pubmed

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.

CYFIP1 CUX1

1.99e-047108230687000
Pubmed

Inhibition of atrogin-1/MAFbx mediated MyoD proteolysis prevents skeletal muscle atrophy in vivo.

MYH13 LAMA1

1.99e-047108219319192
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

KRT2 PLOD3 VPS13C SCYL1 CHD4 CYFIP1 SMC3 AMOTL2 RAB32 MVP

2.06e-048031081036517590
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

PNMA1 KRT80 AKAP9 CEP250 MAD1L1

2.12e-04173108536217029
InteractionVPS33B interactions

PLOD3 LSG1 C9orf78 UPF2 RABEP1 SYNE2 CEP83 CEP152 ARHGEF2

1.16e-061991079int:VPS33B
InteractionKRT19 interactions

KRT2 CHD3 CHD4 KRT80 RNF123 AKAP9 CDK5RAP2 PAWR CEP152 AMOTL2

2.61e-0628210710int:KRT19
InteractionKRT8 interactions

KRT2 EPPK1 LSG1 CHD3 ADAM12 AKAP9 RABEP1 CFAP45 PHLPP1 CDK5RAP2 CEP152 CUX1

3.94e-0644110712int:KRT8
InteractionYWHAH interactions

KIF13B EPPK1 DOCK11 LSG1 CYTH2 FRYL NEK1 CYFIP1 AKAP9 RABEP1 SYNE2 CGN MAD1L1 CEP152 CGNL1 ARHGEF2 TSC22D4 AMOTL2

1.89e-05110210718int:YWHAH
InteractionTNIK interactions

CACNA2D1 DOCK11 LSG1 TIAM2 CYFIP1 AKAP9 SYNE2 NGEF ARHGEF2 MVP

3.58e-0538110710int:TNIK
InteractionNDC80 interactions

AKAP9 CEP250 SYNE2 MAD1L1 OSBPL1A ASPM CDK5RAP2 CEP152 AMOTL2

4.32e-053121079int:NDC80
InteractionMBD3L2 interactions

CHD3 CHD4 AHCYL2 CHD5

6.54e-05411074int:MBD3L2
InteractionSTIL interactions

DEF8 AKAP9 CGN ASPM CDK5RAP2 CEP152 CGNL1

6.98e-051901077int:STIL
InteractionHDAC1 interactions

C9orf78 ATG2B USP24 CHD3 CHD4 NEK1 RNF123 AKAP9 SMC3 RABEP1 CHD5 CEP250 SYNE2 MAD1L1 PHLPP1 CDK5RAP2 CUX1

7.24e-05110810717int:HDAC1
InteractionRYR1 interactions

CACNA2D1 RYR1 RNF123 XIRP2

7.90e-05431074int:RYR1
InteractionKRT32 interactions

KRT2 EPPK1 CHD4 KRT80

8.66e-05441074int:KRT32
CytobandEnsembl 112 genes in cytogenetic band chr7q22

PLOD3 SLC26A4 MYH16 TSC22D4 CUX1

1.77e-042191085chr7q22
Cytoband7q21-q22

CACNA2D1 AKAP9

2.44e-041010827q21-q22
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD4 CHD5

1.04e-05126731305
GeneFamilyMyosin heavy chains

MYH3 MYH13 MYH16

2.14e-05156731098
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TIAM2 ARHGEF40 NGEF ARHGEF2

1.04e-0466674722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 CYTH2 TIAM2 CADPS PHLPP1 ARHGEF2

1.14e-04206676682
GeneFamilyPHD finger proteins

KAT6A CHD3 CHD4 CHD5

3.46e-049067488
GeneFamilyLaminin subunits

LAMB4 LAMA1

8.72e-0412672626
GeneFamilyNon-clustered protocadherins

PCDH11Y PCDH11X

8.72e-041267221
GeneFamilyDNA polymerases

REV3L POLQ

3.25e-0323672535
GeneFamilyFibrinogen C domain containing

ANGPTL1 TNXB

3.84e-0325672554
GeneFamilyKeratins, type II

KRT2 KRT80

4.47e-0327672609
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP9 RAB32

5.15e-0329672396
CoexpressionPGF_UP.V1_UP

AHCYL2 REV3L MMRN1 NEK1 AKAP9 UPF2 SMC3 SYNE2

1.25e-061901088M2674
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

KAT6A USP24 FRYL REV3L NEK1 TAOK3 AKAP9 UPF2 SMC3 SYNE2 MAD1L1 NAV3 PHLPP1 PAWR CUX1

2.35e-0685610815M4500
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

IARS1 VPS13C REV3L NEK1 TAOK3 SMC3 RABEP1 SYNE2 OSBPL1A ASPM CDK5RAP2 POLQ TCEAL9

3.13e-0665610813M18979
CoexpressionDAZARD_UV_RESPONSE_CLUSTER_G6

KAT6A USP24 FRYL REV3L NAV3 PHLPP1

3.11e-051451086M1810
CoexpressionSAGIV_CD24_TARGETS_UP

VPS13C FRYL ASPM

9.90e-05221083M4144
CoexpressionDESCARTES_FETAL_ADRENAL_MEGAKARYOCYTES

CCDC175 MMRN1 XIRP2 CFAP45 TUBAL3

1.11e-041141085M40146
CoexpressionLU_AGING_BRAIN_UP

FRYL AHCYL2 RYR1 SMC3 PHLPP1 TSC22D4 AMOTL2

1.11e-042631087M5547
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

KAT6A USP24 FRYL REV3L AKAP9 UPF2 PHLPP1 PAWR CUX1

1.36e-044661089M13522
CoexpressionBUSSLINGER_GASTRIC_X_CELLS

KIF13B VPS13C REV3L SEZ6L2 MMRN1 AKAP9

1.43e-041911086M40019
CoexpressionSHEPARD_CRASH_AND_BURN_MUTANT_DN

KRT2 AKAP9 CHD5 CEP250 ASPM TNXB

1.43e-041911086M2148
CoexpressionCREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2

KIF6 PNMA1 ODAD1 CFAP43 REV3L TRIM22 CFAP45 NGEF CFAP57

1.47e-044711089M3062
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

CHD3 JAKMIP3 REV3L SEZ6L2 TAOK3 AKAP9 CADPS CHD5 NAV3 RAB11FIP4

1.53e-0458410810M39068
CoexpressionGSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP

PNMA1 CYTH2 NEK1 CADPS SYNE2 POLQ

1.56e-041941086M7467
CoexpressionTRAVAGLINI_LUNG_CILIATED_CELL

PNMA1 EPPK1 ODAD1 CYTH2 RGS22 CFAP43 KRT80 NEK1 CFAP54 AKAP9 SYNE2 CEP83 CFAP45 CFAP57

1.60e-04109310814M41649
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH2_UP

AHCYL2 TRIM22 AKAP9 SYNE2 TNXB TCEAL9

1.65e-041961086M5381
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH1_UP

AHCYL2 AKAP9 SYNE2 RAB11FIP4 TNXB CUX1

1.69e-041971086M5378
CoexpressionGSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP

KIF13B PLOD3 VPS39 BSN LY86 ATP2B3

1.79e-041991086M5266
CoexpressionGSE17721_POLYIC_VS_CPG_8H_BMDC_UP

CHD4 TLR9 SLC30A1 RYR1 CADPS LY86

1.79e-041991086M3945
CoexpressionGSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN

SAMD1 REV3L ANGPTL1 CYFIP1 PAWR RAB11FIP4

1.79e-041991086M6030
CoexpressionGSE14308_TH17_VS_NATURAL_TREG_DN

SLC26A4 CHD4 SLC30A1 RNF123 RAB11FIP4 DNAH8

1.84e-042001086M3390
CoexpressionGSE15215_CD2_POS_VS_NEG_PDC_DN

MYH3 VPS39 NEK1 AKAP9 COQ9 CFAP45

1.84e-042001086M3521
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

CACNA2D1 REV3L NEK1 AKAP9 SMC3 RABEP1 SYNE2 CEP83 ASPM PALM3 POLQ CUX1

5.08e-0831110612Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

CACNA2D1 LAMA1 FRYL AHCYL2 REV3L NEK1 AKAP9 SMC3 RABEP1 SYNE2 CEP83 PCDH11X ASPM PALM3 PHLPP1 PAWR POLQ CUX1

1.82e-0698910618Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

AKAP9 SMC3 RABEP1 SYNE2 CEP83 ASPM PALM3 POLQ

5.47e-061921068Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

CACNA2D1 VPS13C AHCYL2 TAOK3 AKAP9 SMC3 RTL1 RABEP1 SYNE2 CGN CEP83 PCDH11X ASPM PALM3 PHLPP1 POLQ CUX1

7.19e-0698310617Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA2D1 KAT6A USP24 ANGPTL1 NEK1 AKAP9 UPF2 SMC3 SYNE2 CEP83 PALM3 CDK5RAP2

7.15e-0562910612Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100

CACNA2D1 REV3L CUX1

7.81e-05171063gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA2D1 VPS13C TAOK3 AKAP9 SMC3 RABEP1 SYNE2 COQ9 CEP83 ASPM POLQ CUX1

1.03e-0465410612Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500

CHD4 REV3L NEK1 AKAP9 ASPM CUX1

1.33e-041561066gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

FRYL AKAP9 SMC3 RABEP1 SYNE2 CEP83 ASPM PALM3 PHLPP1 POLQ

1.96e-0449810610Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 AKAP9 SYNE2 CFAP57

1.33e-09197108974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45 CFAP57

1.74e-08185108830f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45 CFAP57

2.06e-08189108827329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 VPS13C FRYL CHD4 REV3L SEZ6L2 AKAP9 CADPS

2.62e-0819510883e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 VPS13C FRYL CHD4 REV3L SEZ6L2 AKAP9 CADPS

2.62e-0819510887796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45 CFAP57

3.19e-082001088926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45 CFAP57

3.19e-08200108806ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

KIF6 RGS22 CCDC175 CFAP43 CFAP54 CFAP45 CFAP57

2.58e-071771087c38138fb5ad9766c2d240811210c854338cd612e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45

2.68e-071781087de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPPK1 ODAD1 RGS22 CFAP43 CFAP54 NGEF CFAP57

2.90e-07180108792fb01b91261b3103454924cde56add337b41844
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.01e-071811087dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.12e-0718210877ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.12e-071821087fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.36e-0718410875daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.48e-07185108718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.75e-0718710879e10ed56090d82589bc457788282f664b70ace4b
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.88e-07188108761a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

ODAD1 RGS22 CFAP43 NEK1 CFAP54 CEP83 CFAP45

3.88e-0718810878f30535a32968a81a304315a49c0d90a77d36948
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.88e-07188108734b11f72ca73153d02edcd09b38983ad1a504659
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF6 EPPK1 RGS22 CFAP43 CGN CFAP45 CFAP57

3.88e-0718810870eca3dc93724e23b71e687fc24fa9f1e89bdef6a
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.88e-0718810872b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF6 EPPK1 RGS22 CFAP43 CGN CFAP45 CFAP57

3.88e-0718810879ce3e1fffce87ad19812ecbf9b7f9935a975d676
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF6 ODAD1 RGS22 CCDC175 CFAP43 CFAP54 CFAP45

4.03e-071891087a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

4.03e-07189108768a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

4.03e-071891087b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

5.70e-0719910872498237b9e895ca4826a3378d9d40989968df72b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

5.70e-071991087542ec45c931b40738df1f3777b00c83be33a514a
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

5.89e-072001087f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

MYH3 RYR1 XIRP2 SRL CGNL1 MYO18B ATP2B3

5.89e-07200108713ec8afea86e4a10599c924871ba4e325b0a8013
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RYR1 XIRP2 CADPS NAV3 MYO18B DNAH8

2.52e-0615910865335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCiliated_cells-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

KIF6 ODAD1 RGS22 CFAP43 CFAP45 CFAP57

3.34e-061671086edb722ee9b6ccd00fb038f702be8664020932659
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PNMA1 RGS22 CFAP43 CFAP45 CFAP57 TUBAL3

3.46e-061681086fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PNMA1 RGS22 CFAP43 CFAP45 CFAP57 TUBAL3

3.46e-0616810867edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ODAD1 CCDC175 CFAP43 CFAP54 CEP83 CFAP57

3.58e-061691086fba841664939c771881ba97f14ef1df6635c04ff
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

KIF13B RGS22 CFAP43 CFAP54 CFAP45 CFAP57

3.83e-06171108674be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KIF6 EPPK1 RGS22 CFAP43 CFAP54 CFAP57

4.38e-061751086c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CACNA2D1 DOCK11 RGS22 REV3L NEK1 NAV3

5.84e-06184108667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PNMA1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

5.84e-061841086797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PNMA1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

5.84e-06184108677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

6.02e-0618510864fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

6.21e-06186108676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCelldroplet-Lung-nan-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 EPPK1 RGS22 CFAP43 CFAP45 CFAP57

6.21e-061861086740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB4 MYH13 VPS13C RGS22 UPF2 DNAH8

6.21e-06186108623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 EPPK1 RGS22 CFAP43 CFAP45 CFAP57

6.21e-0618610865ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP57

6.40e-061871086f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A4 CHD3 CADPS CHD5 BSN ATP2B3

6.40e-061871086e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A4 CHD3 CADPS CHD5 BSN ATP2B3

6.40e-06187108624cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A4 CHD3 CADPS CHD5 BSN ATP2B3

6.40e-0618710862f153b203fe79f206319603cf94d3a03ab49a05d
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF6 EPPK1 RGS22 CFAP43 CFAP45 CFAP57

6.81e-061891086fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.01e-061901086169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.01e-0619010860cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.01e-0619010867031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 ODAD1 RGS22 CFAP43 CGN CFAP45

7.01e-06190108673ac7be02742ee6cb003600631f6a03eecbf2083
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF40 XIRP2 OSBPL1A SRL MYO18B TNXB

7.01e-06190108696a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP57

7.23e-061911086e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP57

7.23e-0619110869d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIF6 ODAD1 RGS22 CFAP43 CFAP54 CFAP57

7.23e-0619110861c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.45e-061921086097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.45e-061921086b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellControl-PLT_1|World / Disease Group and Platelet Clusters

PNMA1 KAT6A TAOK3 AKAP9 TSC22D4 RAB32

7.45e-061921086f595eba81911eb860dce964f1d8269287f50d3ea
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ODAD1 CFAP43 CFAP54 CGN CFAP45 CFAP57

7.90e-061941086756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.90e-0619410861ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

7.90e-06194108643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A USP24 ARHGEF40 CYFIP1 NAV3 MYO18B

8.14e-061951086a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF6 ODAD1 RGS22 CFAP43 CFAP45 CFAP57

8.14e-06195108607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

8.38e-06196108627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

8.62e-0619710866865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

AKAP9 UPF2 ASPM CDK5RAP2 CEP152 TCEAL9

8.62e-0619710860fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

VPS13C REV3L AKAP9 SMC3 SYNE2 OSBPL1A

9.13e-061991086fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.13e-0619910869700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.13e-0619910861188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.13e-0619910862e8ace105c4e2405baa06d953e52888b54e2d055
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-0620010869ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-06200108652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-06200108655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-062001086a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-0620010866a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SEZ6L2 AKAP9 CADPS CHD5 MAD1L1 CUX1

9.40e-062001086bad32a95b759fad509401b07bc96a56687c2a592
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-062001086721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-062001086dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-06200108685c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-0620010863bba5219453322198e8fdb0921d5f8c403598751
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-062001086bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-062001086f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-06200108621bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-062001086d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-06200108612bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

MYH3 CACNA2D1 RYR1 XIRP2 SRL MYO18B

9.40e-0620010860f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-062001086a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK11 RYR1 CYFIP1 RABEP1 NAV3 LY86

9.40e-06200108633036d21c1c82109284473a515c4f890b33fdd5c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ODAD1 RGS22 CFAP43 CFAP54 CFAP45 CFAP57

9.40e-062001086cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH13 ODAD1 KRT80 ASPM CFAP57

3.15e-051491085a6406c4c9404271a2f4c615c6cd3265b2d759b12
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A4 CHD3 MMRN1 CHD5 BSN

3.81e-05155108572a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC175 ASPM CEP152 POLQ DNAH8

4.05e-0515710850fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC30A1 ARHGEF40 CEP250 LY86 TNXB

4.05e-0515710854d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC30A1 ARHGEF40 CEP250 LY86 TNXB

4.05e-0515710852c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

RGS22 CCDC175 CFAP43 CFAP54 CFAP45

4.98e-051641085fd30c55d0d75ef8b9396435d836187168095152b
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 RGS22 CFAP43 CFAP45 CFAP57

4.98e-0516410850e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ODAD1 RGS22 SEZ6L2 CFAP45 CFAP57

5.59e-0516810859a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEF8 AHCYL2 ASPM CEP152 POLQ

5.59e-051681085a7eb28e15b591997f1aee09501cb20ae18beca08
DiseaseAutosomal recessive primary microcephaly

ASPM CDK5RAP2 CEP152

1.82e-05151033cv:C3711387
DiseasePrimary microcephaly

ASPM CDK5RAP2 CEP152

6.06e-05221033C0431350
DiseaseAutosomal Recessive Primary Microcephaly

ASPM CDK5RAP2 CEP152

6.06e-05221033C3711387
DiseaseMultiple pterygium syndrome

MYH3 RYR1

7.21e-0541032C0265261
Diseaselymphoma (is_implicated_in)

CHD4 MAD1L1

1.79e-0461032DOID:0060058 (is_implicated_in)
Diseasemicrocephaly (implicated_via_orthology)

MAD1L1 ASPM CDK5RAP2

1.90e-04321033DOID:10907 (implicated_via_orthology)
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

RNF123 BSN

2.51e-0471032EFO_0020797
Diseasemicrocephaly (is_implicated_in)

ASPM CDK5RAP2

3.33e-0481032DOID:10907 (is_implicated_in)
Diseaseinterleukin 18 receptor accessory protein measurement

IL18RAP TNXB

4.28e-0491032EFO_0008179
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH3 MYH13

5.33e-04101032DOID:0111596 (implicated_via_orthology)
Diseasehepatocellular carcinoma (is_marker_for)

PLOD3 CHD4 TLR9 CHD5 ASPM CUX1

6.70e-043011036DOID:684 (is_marker_for)
Diseasedistal myopathy (implicated_via_orthology)

MYH3 MYH13

7.78e-04121032DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH3 MYH13

7.78e-04121032DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH3 MYH13

9.18e-04131032DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH3 MYH13

1.23e-03151032DOID:0050646 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

MICAL1 KIF6 VPS39 JAKMIP3 ADAM12 STX12 AKAP9 CHD5 SYNE2 TSC22D4 CUX1

1.33e-03107410311C0006142
Diseaselevel of Sphingomyelin (d32:1) in blood serum

RABEP1 SYNE2

1.59e-03171032OBA_2045173
DiseaseMyeloid Leukemia

ATG2B SMC3

1.78e-03181032C0023470
DiseaseLeukemia, Monocytic, Chronic

ATG2B SMC3

1.78e-03181032C0023466
DiseaseEndometrial Carcinoma

CHD4 PAWR CUX1

2.07e-03721033C0476089
DiseaseBrugada Syndrome (disorder)

CACNA2D1 AKAP9

3.17e-03241032C1142166
DiseaseColorectal Carcinoma

LAMA1 TLR9 AKAP9 PUS10 CHD5 PCDH11X DNAH8 CUX1

3.23e-037021038C0009402

Protein segments in the cluster

PeptideGeneStartEntry
LRLSEQLREKEEQIL

AMOTL2

546

Q9Y2J4
IEKLEFRVRELEQAL

AKAP9

2146

Q99996
LELQVLLESEKVRIR

AKAP9

3296

Q99996
VKERNVRIREIILDL

CFAP43

1041

Q8NDM7
ELILLQEEKVRFQLN

CFAP43

1421

Q8NDM7
DITRNLEARILKIEV

CFAP54

2106

Q96N23
VVRDDILLLKNEIQV

CEP152

616

O94986
QKVLDIFEQRLEQVE

ARHGEF40

851

Q8TER5
LNIAEIVRLVQRFEE

CCDC7

191

Q96M83
RRFKLLEQALVIEEQ

CHD5

1791

Q8TDI0
ELQQKDRALVELLRE

ARHGEF2

596

Q92974
EVLNIRLQRESKELI

ADAM12

66

O43184
VLSRQKREIDVLQLV

ANGPTL1

91

O95841
LVVLQDEKLELENRL

CEP83

391

Q9Y592
EREKAARIIQLAVIN

ASPM

1291

Q8IZT6
VLDLKRDFQPVREQI

ATP2B3

551

Q16720
QVFIVQDLEIRDRLA

ATG2B

1641

Q96BY7
ESLKRELQEREQLLI

CDK5RAP2

111

Q96SN8
EKEVVRERQENLRLV

PAWR

276

Q96IZ0
IEEAARFLVEKILVN

RAB32

181

Q13637
QRVAELEKINAEFLR

RABEP1

16

Q15276
RLEFQKEREATQELI

RAB11FIP4

486

Q86YS3
KAERELEVQIQRLNI

GOLGA8S

126

H3BPF8
LEVIAEKRRLQEEIR

PALM3

11

A6NDB9
EEELQRRILVLEKLN

PAPOLB

56

Q9NRJ5
QTLRILIEENRKVIA

PLOD3

401

O60568
EIKERLRVLLENQIT

CADPS

781

Q9ULU8
ERIRKFQILNDEIIT

CYFIP1

1206

Q7L576
IIERNIILEKVTQRD

IL18RAP

316

O95256
RFVVELQQRELALKD

MAD1L1

336

Q9Y6D9
RQLVRLEEEQKLILT

LSG1

141

Q9H089
LAVERAKQVEEFLQR

NEK1

526

Q96PY6
INIRFGIILREDIKE

LY86

66

O95711
KSINVLIRDIVREQF

MMRN1

381

Q13201
LIRDIVREQFKIFQN

MMRN1

386

Q13201
ENVSLIKEINELRRE

CFAP57

1136

Q96MR6
EIKIEISELNRVIQR

KRT2

391

P35908
NLLQVLEKVEEFRIR

KRT80

156

Q6KB66
QLLQLERERVELEKL

BSN

2371

Q9UPA5
KEREIAQLVEDVQRL

CUX1

306

Q13948
FERILRAQREQIEKE

CFAP45

446

Q9UL16
IERNIRNNDLVKIID

NAV3

2201

Q8IVL0
QLLRRVILTEKQELE

DNAH8

3591

Q96JB1
IFVKIIQFIAQERLD

FRYL

406

O94915
RVALIKNEAVLNEEI

KIF6

341

Q6ZMV9
LQLAQQRIKELEERI

JAKMIP3

801

Q5VZ66
DQVLRKLVDLVNQRD

MICAL1

1031

Q8TDZ2
RLVKIRFLIEDINDN

PCDH11X

121

Q9BZA7
EAVERTQQRKLEELL

OSBPL1A

131

Q9BXW6
INKQLEEIRRLEEVR

ODAD1

16

Q96M63
EAELQRVQKVRELEL

MVP

756

Q14764
SDQFVIIRREKLIQD

KAT6A

741

Q92794
KIQVRDLQLVTREAI

PUS10

386

Q3MIT2
IALELNERLIKEDQV

DOCK11

1996

Q5JSL3
TEKIQNAEVRRIELL

CCDC175

481

P0C221
RQLVEIAARDIEKLL

CACNA2D1

76

P54289
IEVAELQRQLQLEVK

CGNL1

621

Q0VF96
RFKLLEQALVIEEQL

CHD3

1796

Q12873
LARANIVEVEVILKN

POLQ

821

O75417
ELLQKAREELRQQLE

CEP250

466

Q9BV73
VLRDQVQKLEERLTD

CEP250

1261

Q9BV73
KQELLVEIQRLREEL

CYTH2

26

Q99418
VEELVEIRKLRQDIL

DEF8

361

Q6ZN54
KADQLRILEDQVVAI

LAMB4

1731

A4D0S4
RLEVVKEFLRNNEDL

CXorf38

271

Q8TB03
RLTRVLEEEQKLVQL

COQ9

156

O75208
FKLLEQALVIEEQLR

CHD4

1786

Q14839
LFQLLVQIREEEAKE

PNMA1

321

Q8ND90
AELEKLIQQRAVLRV

SAMD1

71

Q6SPF0
VEENANVVVRLLIRK

RYR1

2346

P21817
IFRLVKIRFLIEDIN

PCDH11Y

151

Q9BZA8
SIRQVQDLEREFLIK

UPF2

996

Q9HAU5
LDRLRQEVAVKEQLT

KIF13B

1356

Q9NQT8
IVLILQIEEKLAERR

RTL1

351

A6NKG5
FRLVKLNEVIRQVDI

AHCYL2

436

Q96HN2
LRKRLDQVEQELNEL

SMC3

836

Q9UQE7
IQEIELRVKRLQEIL

SYNE2

6586

Q8WXH0
VEVLKEQIRELAERN

TSC22D4

341

Q9Y3Q8
RFVETNLFLEEIQIK

SCYL1

271

Q96KG9
ALEQERILLKIQEEL

RGS22

1216

Q8NE09
VKDVEIQANLLFDRL

LAMA1

2071

P25391
QLIEKAEALRLLEVQ

EPPK1

1996

P58107
LLVQNILKRVEERSE

NGEF

421

Q8N5V2
IKNLLERQEREIETF

TAOK3

861

Q9H2K8
KQIQKLETRIRELEF

MYH3

1811

P11055
VIDLVLERTRKLAEQ

TUBAL3

121

A6NHL2
RFLIQNVLRLQKEEE

IARS1

661

P41252
EEKRILLQVEILNVR

SEZ6L2

561

Q6UXD5
IEAERLQVEKERLQI

MSANTD4

221

Q8NCY6
LLQERLQAEEREKTV

CGN

1056

Q9P2M7
ALNIVEFLRKREELQ

XIRP2

2766

A4UGR9
KDIEIQFQRLRISED

TIAM2

1586

Q8IVF5
EIRELERQQEQLVKI

REV3L

3071

O60673
LRVIVKEFQRIDVNV

SLC26A4

676

O43511
QRLLEDRKDVVVLVI

TLR9

956

Q9NR96
QRLRKRIEVVEELQV

RNF123

491

Q5XPI4
QDLELIKERETAIRQ

STX12

176

Q86Y82
VIENRLENKIAFIRQ

SRL

321

Q86TD4
RQILFLIEQIDVLKA

SUN3

121

Q8TAQ9
QALRVRLEILEELVK

TNXB

101

P22105
IQKLENRVRELENEL

MYH13

1816

Q9UKX3
VEIKNVQLLFARAEE

VPS13C

751

Q709C8
RERLIQSLQEFKEDI

TCEAL9

46

Q9UHQ7
LRNNIERVEKVIILQ

TRIM60

151

Q495X7
IKQLEQLRQRFELEI

MYO18B

1711

Q8IUG5
VIRIQLELAQVKADI

MYH16

721

Q9H6N6
LIKIFLLECNVREVR

USP24

2221

Q9UPU5
LNVIRKLIADEVDFL

PHLPP1

816

O60346
EVRLKLEETREVQNL

C9orf78

26

Q9NZ63
IDIRNLIKELRNVEG

SLC30A1

351

Q9Y6M5
RVILDNEEQRELQKL

TRIM22

191

Q8IYM9
QINDIRIFLEKVLEE

VPS39

796

Q96JC1