Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	1.88e-08	5	158	4	GO:0030156
GeneOntologyMolecularFunction	chromatin binding	SOX10 TSHZ3 PCGF2 KLF14 CHD3 ACSS2 BAHD1 ZNF750 SALL1 BRCA1 PRKCB ASXL2 USP3 PHF10 CRAMP1 CBX2 BAHCC1	8.04e-05	739	158	17	GO:0003682
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	TSPOAP1 VPS54 RIMBP3 RIMBP3C RIMBP3B	7.70e-06	36	158	5	GO:0007274
Domain	FN3_dom	IL12RB2 LRIT2 FLNC DSCAM TSPOAP1 FNDC3A VWA1 RIMBP3 RIMBP3C RIMBP3B	9.40e-06	209	154	10	IPR003961
Domain	FN3	IL12RB2 LRIT2 FLNC DSCAM TSPOAP1 FNDC3A VWA1 RIMBP3C RIMBP3B	2.33e-05	185	154	9	SM00060
Domain	FN3	IL12RB2 LRIT2 DSCAM TSPOAP1 FNDC3A VWA1 RIMBP3 RIMBP3C RIMBP3B	4.13e-05	199	154	9	PS50853
Domain	SH3_2	SASH1 TSPOAP1 RIMBP3 RIMBP3C RIMBP3B DNMBP	7.78e-05	86	154	6	PF07653
Domain	SH3_2	SASH1 TSPOAP1 RIMBP3 RIMBP3C RIMBP3B DNMBP	7.78e-05	86	154	6	IPR011511
Domain	TACC	TACC2 TACC3	2.02e-04	3	154	2	PF05010
Domain	TACC	TACC2 TACC3	2.02e-04	3	154	2	IPR007707
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F FLNC HIP1 MYO9B MEX3D INTS1 ADGRB2 LAMB3 GTF2IRD1 POM121C BAHD1 C2CD2 CASZ1 C6orf132 PPP1R26 HIVEP3 GAS2L1 C2CD3 PWWP2B CDK13 BTBD7 RPTOR DISP2 RIPOR1 CACNA1H DNMBP CRAMP1 WNK2 PRRC2B IQCE CBX2 BAHCC1	8.61e-17	1105	161	32	35748872
Pubmed	Interaction network of human early embryonic transcription factors.	TSHZ3 TCF20 SCAND1 ZNF217 ZHX2 POM121C PRDM2 ZNF512B BPTF SALL1 ZNF608 ASXL2 PHF10 ZMYM3 PRRC2B BAHCC1	9.89e-12	351	161	16	38297188
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TCF20 TSPOAP1 STXBP5 ZHX2 SNX19 ARFGEF3 BTBD7 MAST1 DISP2 RIPOR1 CACNA1H ASXL2 SRRM2 ZMYM3 PRRC2B	8.57e-10	407	161	15	12693553
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	2.20e-09	5	161	4	17855024
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PPFIBP2 AFF3 RTN3 FAM117B CHD3 VPS54 GTF2IRD1 ZHX2 SHROOM2 C2CD2 CASZ1 ARFGEF3 HIVEP3 BPTF PWWP2B ZNF608 CDK13 RPTOR MAST1 RIPOR1 CACNA1H USP3 CRAMP1 WNK2	1.04e-07	1489	161	24	28611215
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SEMA4F TCF20 SHROOM2 NACAD CASZ1 MAST1 SRRM2 CRAMP1 WNK2 IQCE	1.51e-07	233	161	10	37704626
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SASH1 SMPD4 FNDC3A NACAD BAHD1 ZNF512B STOX2 ZNF608 RPTOR DNMBP CRAMP1 WNK2 IQCE PPP6R3	1.96e-07	529	161	14	14621295
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	3.88e-07	4	161	3	19091768
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C TDRD6 RIMBP3B	4.27e-07	14	161	4	17662146
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TCF20 CHD3 ZNF217 GTF2IRD1 PRDM2 BPTF PWWP2B CDK13 RPTOR RIPOR1 TACC3 DNMBP SRRM2 PHF10 ZMYM3 PPP6R3	7.01e-07	774	161	16	15302935
Pubmed	Human transcription factor protein interaction networks.	SOX10 TSHZ3 TCF20 CHD3 ZNF217 ZHX2 POM121C PRDM2 ZNF512B BPTF SALL1 BRCA1 ZNF608 DCP1B DGKK ASXL2 SRRM2 PHF10 ZMYM3 PRRC2B PPP6R3 CBX2	8.07e-07	1429	161	22	35140242
Pubmed	A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.	INTS1 UNC79 BAHCC1	9.67e-07	5	161	3	16807365
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	AMPD2 FAM117B ZNF217 HMMR GTF2IRD1 C6orf132 DMRT3 CCDC120 TACC3 PRRC2B	1.86e-06	307	161	10	37499664
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	JCAD AMPD2 TSHZ3 TCF20 ZNF217 ZHX2 CASZ1 PRDM2 SALL1 ZNF608 BAHCC1	2.76e-06	398	161	11	35016035
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD CDK18 AMPD2 TCF20 SASH1 NAA10 FAM117B C6orf132 ARFGEF3 STOX2 C2CD3 DCP1B RPTOR DNMBP SRRM2 MACIR	2.77e-06	861	161	16	36931259
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MYO9B RTN3 TACC2 ZNF217 UPF3B RIMBP3 ARFGEF3 SALL1 RPTOR DNMBP ZMYM3 PRRC2B PPP6R3	3.94e-06	588	161	13	38580884
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	JCAD TSHZ3 TSPOAP1 PPFIBP2 POM121C MAP3K1 C6orf132 SALL1 HSH2D WNK2 IQCE	5.76e-06	430	161	11	35044719
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TSHZ3 RNF31 MYO9B AFF3 CASP4 LAMB3 FAM117B TACC2 UPF3B SNX19 ZNF608 FARS2 RIPOR1 ASCC3 MOCS1 PRRC2B PPP6R3 CBX2	1.47e-05	1215	161	18	15146197
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	IL12RB2 RNF31 CHD3 POM121C ZNF512B BPTF PWWP2B BRCA1 ZNF608 RPTOR ASCC3 SRRM2 PHF10 ZMYM3 PRRC2B SPATC1L BAHCC1	1.81e-05	1116	161	17	31753913
Pubmed	A genome-wide association study (GWAS) for bronchopulmonary dysplasia.	HTR1A STXBP5 HIVEP3 PRR16	1.84e-05	34	161	4	23897914
Pubmed	SOX10 regulates an alternative promoter at the Charcot-Marie-Tooth disease locus MTMR2.	SOX10 MTMR2	2.13e-05	2	161	2	27466180
Pubmed	Genomic Knockout of Two Presumed Forelimb Tbx5 Enhancers Reveals They Are Nonessential for Limb Development.	UNCX TBX5	2.13e-05	2	161	2	29898387
Pubmed	The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis.	TACC2 TACC3	2.13e-05	2	161	2	11847113
Pubmed	A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth.	KLF11 KLF14	2.13e-05	2	161	2	21171965
Pubmed	SOX10 deficiency-mediated LAMB3 upregulation determines the invasiveness of MAPKi-resistant melanoma.	SOX10 LAMB3	2.13e-05	2	161	2	38102338
Pubmed	TACC3 expression is tightly regulated during early differentiation.	TACC2 TACC3	2.13e-05	2	161	2	12711550
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX10 KLF11 TSHZ3 UNCX THAP10 MESP1 ZHX2 PRDM2 HIVEP3 BCL6B SALL1 DMRT3 DLX4 CRAMP1 TBX5	2.29e-05	908	161	15	19274049
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	TACC2 CEP164 TACC3	2.69e-05	13	161	3	17920017
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TSHZ3 TCF20 CHD3 ZNF217 PRDM2 SALL1 ZNF608 TACC3 ASCC3 ZMYM3	2.74e-05	418	161	10	34709266
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SOX10 KLF11 PCGF2 TCF20 RNF31 TACC2 ZNF217 GTF2IRD1 BRCA1 DLX4 TACC3 PHF10 ZMYM3	2.84e-05	709	161	13	22988430
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TSHZ3 TCF20 INTS1 CHD3 CASZ1 PRDM2 ZNF512B BPTF BRCA1 USP3 ZMYM3 CBX2	2.87e-05	608	161	12	36089195
Pubmed	The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.	TACC2 TACC3	6.37e-05	3	161	2	11121038
Pubmed	The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer.	TACC2 TACC3	6.37e-05	3	161	2	15226440
Pubmed	Negative regulation of BRCA1 by transforming acidic coiled-coil protein 3 (TACC3).	BRCA1 TACC3	6.37e-05	3	161	2	29355525
Pubmed	Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis.	UNCX MESP1	6.37e-05	3	161	2	16996494
Pubmed	Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.	SOX10 BRCA1	6.37e-05	3	161	2	30174241
Pubmed	Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.	ZNF750 RPTOR	6.37e-05	3	161	2	24005976
Pubmed	Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.	MAP3K1 BRCA1	6.37e-05	3	161	2	20809358
Pubmed	RANKL and RANK: From Mammalian Physiology to Cancer Treatment.	TNFRSF11A BRCA1	6.37e-05	3	161	2	29241686
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	CHD3 ZNF217 ZMYM3	7.55e-05	18	161	3	12493763
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	INTS1 SMPD4 STOX2 RPTOR UNC79 CRAMP1	8.25e-05	153	161	6	10718198
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TSHZ3 TCF20 CHD3 ZNF512B ZMYM3	1.21e-04	103	161	5	32744500
Pubmed	Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.	RNF31 PRKCB	1.27e-04	4	161	2	17069764
Pubmed	The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines.	TACC2 TACC3	1.27e-04	4	161	2	10366448
Pubmed	Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.	RPTOR ENDOV	1.27e-04	4	161	2	25053281
Pubmed	Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.	TACC2 TACC3	1.27e-04	4	161	2	15207008
Pubmed	RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.	TNFRSF11A BRCA1	1.27e-04	4	161	2	27322743
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	AMPD2 NAA10 TACC2 PRKD3 DCP1B CDK13 RPTOR TACC3 SRRM2 PPP6R3	1.27e-04	503	161	10	16964243
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TCF20 UNCX NAA10 CHD3 ZNF217 UPF3B HMMR PRDM2 BPTF BRCA1 CDK13 ASXL2 SRRM2 ZMYM3 PRRC2B	1.99e-04	1103	161	15	34189442
Pubmed	Shifted Transversal Design smart-pooling for high coverage interactome mapping.	PPFIBP2 ZNF707 CCDC120 FAM124B	2.00e-04	62	161	4	19447967
Pubmed	Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.	PCGF2 CBX2	2.11e-04	5	161	2	15589172
Pubmed	Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.	MAP3K1 BRCA1	2.11e-04	5	161	2	18355772
Pubmed	Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.	HMMR BRCA1	2.11e-04	5	161	2	22110403
Pubmed	The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting.	CDKN1C NAA10	2.11e-04	5	161	2	28943313
Pubmed	A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland.	ANO1 CLCN2	2.11e-04	5	161	2	25646474
Pubmed	Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites.	UNCX MESP1	2.11e-04	5	161	2	15677726
Pubmed	RANKL/RANK control Brca1 mutation- .	TNFRSF11A BRCA1	2.11e-04	5	161	2	27241552
Pubmed	Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders.	DSCAM CDK13	2.11e-04	5	161	2	33004838
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	TSHZ3 ZNF217 POM121C BRCA1 PRRC2B	2.12e-04	116	161	5	30804394
Pubmed	A protein interaction framework for human mRNA degradation.	SMPD4 UPF3B ACSS2 GTF2IRD1 BRCA1 DCP1B SRRM2 SPATC1L	2.27e-04	347	161	8	15231747
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TCF20 SMPD4 POM121C C6orf132 STOX2 DNMBP PRRC2B	2.37e-04	263	161	7	34702444
Pubmed	Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.	SASH1 MYO9B SLC4A2 ZMYM3	2.55e-04	66	161	4	15790807
Pubmed	SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.	PCGF2 BRCA1 SRRM2	2.62e-04	27	161	3	25703348
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TCF20 CHD3 ZNF217 CASZ1 ZNF512B ZNF608 PRRC2B	2.65e-04	268	161	7	33640491
Pubmed	DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells.	PIWIL2 BCL6B NANOS3	2.93e-04	28	161	3	24850856
Pubmed	Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.	PIWIL2 NANOS3	3.16e-04	6	161	2	28115634
Pubmed	A20 controls RANK-dependent osteoclast formation and bone physiology.	RNF31 TNFRSF11A	3.16e-04	6	161	2	36194667
Pubmed	Breast cancer susceptibility variants alter risks in familial disease.	MAP3K1 BRCA1	3.16e-04	6	161	2	19617217
Pubmed	Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.	HMMR BRCA1	3.16e-04	6	161	2	25830658
Pubmed	TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton.	UNCX TACC3	3.16e-04	6	161	2	17359303
Pubmed	PICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells.	MAP3K1 PRKCB	3.16e-04	6	161	2	12826667
Pubmed	SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.	PCGF2 CBX2	3.16e-04	6	161	2	24091011
Pubmed	Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.	MESP1 TBX5	3.16e-04	6	161	2	20691899
Pubmed	Duplications of hox gene clusters and the emergence of vertebrates.	UNCX TBX5	3.16e-04	6	161	2	23501471
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	BNC2 KLF11 TCF20 CHD3 HIVEP3 BPTF ZNF750 SALL1 BTBD7 PHF10 CBX2 TBX5	4.05e-04	808	161	12	20412781
Pubmed	Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.	PCGF2 CBX2	4.40e-04	7	161	2	15964995
Pubmed	Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming.	MESP1 TBX5	4.40e-04	7	161	2	23704920
Pubmed	Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo.	MESP1 TBX5	4.40e-04	7	161	2	26469858
Pubmed	Control of biochemical reactions through supramolecular RING domain self-assembly.	PCGF2 BRCA1	4.40e-04	7	161	2	12438698
Pubmed	Topology and enzymatic properties of a canonical Polycomb repressive complex 1 isoform.	PCGF2 CBX2	4.40e-04	7	161	2	31093962
Pubmed	Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.	UPF3B DCP1B	4.40e-04	7	161	2	12417715
Pubmed	The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.	TACC2 TACC3	4.40e-04	7	161	2	14767476
Pubmed	REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements.	PCGF2 CBX2	4.40e-04	7	161	2	21402785
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FLNC TCF20 INTS1 RTN3 LAMB3 SMPD4 FNDC3A CASZ1 ZNF707 ZNF608 RPTOR SRRM2 USP3 ZMYM3 PPP6R3	4.97e-04	1203	161	15	29180619
Pubmed	Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos.	HMMR GTF2IRD1 WNK2	5.24e-04	34	161	3	7490078
Pubmed	Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.	CDKN1C RPTOR TBX5	5.24e-04	34	161	3	23342106
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	VPS54 PPP1R26 ARFGEF3 SPOCD1	5.32e-04	80	161	4	19389623
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	TCF20 PWWP2B BTBD7 CRAMP1 MACIR BAHCC1	5.43e-04	217	161	6	34048709
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	HIP1 GTF2IRD1 POM121C	5.72e-04	35	161	3	11013070
Pubmed	Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.	CDKN1C TBX5	5.86e-04	8	161	2	15143159
Pubmed	Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis.	SOX10 UNCX	5.86e-04	8	161	2	15469977
Pubmed	Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis.	UNCX MESP1	5.86e-04	8	161	2	21224256
Pubmed	Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation.	SOX10 UNCX	5.86e-04	8	161	2	19403658
Pubmed	Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model.	TACC2 TACC3	5.86e-04	8	161	2	14602875
Pubmed	BRACHYURY directs histone acetylation to target loci during mesoderm development.	UNCX LAMB3	5.86e-04	8	161	2	29141987
Pubmed	Glycogen synthase kinase-3: properties, functions, and regulation.	PRKD3 PRKCB	5.86e-04	8	161	2	11749387
Pubmed	Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling.	SOX10 UNCX	5.86e-04	8	161	2	16319111
Pubmed	Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons.	SOX10 MESP1	5.86e-04	8	161	2	22040872
Pubmed	Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle.	CDKN1C SALL1	5.86e-04	8	161	2	24742196
Pubmed	Early patterning and specification of cardiac progenitors in gastrulating mesoderm.	MESP1 TBX5	5.86e-04	8	161	2	25296024
Interaction	TOP3B interactions	SEMA4F FLNC HIP1 MYO9B MEX3D INTS1 ADGRB2 LAMB3 GTF2IRD1 POM121C BAHD1 C2CD2 CASZ1 C6orf132 PPP1R26 HIVEP3 GAS2L1 C2CD3 PWWP2B CDK13 BTBD7 RPTOR DISP2 RIPOR1 CACNA1H DNMBP ADAMTSL4 CRAMP1 WNK2 PRRC2B IQCE CBX2 BAHCC1	2.25e-08	1470	156	33	int:TOP3B
Interaction	FEV interactions	TCF20 ZNF217 ZHX2 ZNF512B SALL1 ZNF608 ASXL2 PHF10 ZMYM3 PRRC2B CBX2	5.38e-07	203	156	11	int:FEV
Interaction	CRX interactions	SOX10 TCF20 ZNF217 ZHX2 ZNF512B SALL1 ZNF608 ASXL2 PHF10 ZMYM3 PRRC2B BAHCC1	7.00e-07	254	156	12	int:CRX
Interaction	TEAD1 interactions	TSHZ3 CHD3 ZNF217 ZHX2 BPTF SALL1 ZNF608 ASXL2 PHF10 CBX2	1.17e-06	176	156	10	int:TEAD1
Interaction	PAX6 interactions	SOX10 TSHZ3 DSCAM CHD3 ZHX2 ZNF512B BPTF SALL1 ZNF608 ASXL2 PHF10 ZMYM3 PRRC2B	5.68e-06	366	156	13	int:PAX6
Interaction	MDFI interactions	DBF4B LAMB3 BAHD1 ZNF707 ZNF512B BCL6B DMRT3 FARS2 ZNF648 ETNK2 CCDC120 FAM124B MACIR CBX2	6.65e-06	430	156	14	int:MDFI
Interaction	YWHAE interactions	JCAD CDK18 AMPD2 SASH1 RNF31 PPFIBP2 FAM117B TACC2 SHROOM2 MAP3K1 C6orf132 ZNF750 STOX2 BRCA1 DCP1B CDK13 RPTOR MTMR2 MAST1 PRKCB ASXL2 DNMBP SRRM2 MACIR WNK2	1.23e-05	1256	156	25	int:YWHAE
Interaction	SP7 interactions	TSHZ3 TCF20 CHD3 ZNF217 BRCA1 ZNF608 DLX4 FAM124B PHF10 PRRC2B PPP6R3	2.57e-05	304	156	11	int:SP7
Interaction	RBBP4 interactions	TSHZ3 TCF20 CHD3 ZHX2 ZNF512B BPTF PWWP2B SALL1 BRCA1 RPTOR ASXL2 ASCC3 SRRM2 ZMYM3 BAHCC1	4.02e-05	573	156	15	int:RBBP4
Interaction	CBX3 interactions	KLF11 PCGF2 TCF20 CHD3 ZNF217 GTF2IRD1 BAHD1 ZNF512B ZNF750 BRCA1 ASXL2 SRRM2 PHF10 ADAMTSL4 ZMYM3 PRRC2B	4.28e-05	646	156	16	int:CBX3
Interaction	MID2 interactions	CDK18 BAHD1 BCL6B DMRT3 BRCA1 FARS2 ZNF648 ETNK2 CCDC120 ADAMTSL4	4.53e-05	267	156	10	int:MID2
Interaction	KRTAP10-3 interactions	NAA10 THAP10 BAHD1 BCL6B DMRT3 FARS2 DDX43 FAM124B ADAMTSL4 CBX2	1.01e-04	294	156	10	int:KRTAP10-3
Interaction	ZNF202 interactions	DSCAM NAA10 SCAND1 ZMYM3	1.05e-04	32	156	4	int:ZNF202
Cytoband	17q25.3	ZNF750 RPTOR ENDOV CBX2 BAHCC1	3.01e-05	101	161	5	17q25.3
Cytoband	7p22.3	UNCX INTS1 IQCE	2.34e-04	34	161	3	7p22.3
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	BNC2 KLF11 TSHZ3 KLF14 ZNF217 ZHX2 CASZ1 ZNF707 HIVEP3 BCL6B SALL1 ZNF608 ZNF648	1.79e-04	718	101	13	28
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_SMG_CELL	SOX10 KLF11 PPFIBP2 STXBP5 ANO1 CASP4 TACC2 ZNF217 MESP1 NACAD SNX19 CASZ1 HIVEP3 ZNF750 ITPKC AJM1 HSH2D ARHGEF3 WNK2 IQCE	6.72e-08	775	161	20	M45713
Coexpression	BENPORATH_SUZ12_TARGETS	SOX10 SEMA4F HTR1A CHRDL2 ADGRB2 KLF14 TNFRSF11A MESP1 ABCC6 CASZ1 RIMBP3 DMRT3 ACAN SLC6A5 RIPOR1 RIMBP3C DLX4 RIMBP3B USP3 TBX5	5.97e-06	1035	161	20	M9898
Coexpression	ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	CDKN1C SOX10 CDK18 MYO9B PPFIBP2 SNX19 SLC4A2 MTMR2	6.89e-06	160	161	8	M11011
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	TCF20 TSPOAP1 LINC01547 POM121C C2CD2 PPP1R26 NANOS3 PHF10	1.54e-07	164	161	8	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	TCF20 TSPOAP1 LINC01547 POM121C C2CD2 PPP1R26 NANOS3 PHF10	1.54e-07	164	161	8	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AFF3 MAP3K1 PRDM2 BPTF CDK13 PRKCB RIPOR1 SRRM2	5.53e-07	194	161	8	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	CD8+_Memory_T_cell-RSV-6\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TCF20 HMMR POM121C C2CD2 PPP1R26 NANOS3 PHF10	1.79e-06	158	161	7	5ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF11 CASP4 GAS2L1 ZNF750 ITPKC SLC6A5 BBC3	3.26e-06	173	161	7	0f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	FLNC CYB5RL GTF2IRD1 ZNF707 ARHGEF3 PLOD2 ADAMTSL4	3.94e-06	178	161	7	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	droplet-Lung-LUNG-1m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 LAMB3 VWA1 ARFGEF3 CLCN2 ETNK2 CCDC120	5.26e-06	186	161	7	e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCell	droplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 LAMB3 VWA1 ARFGEF3 CLCN2 ETNK2 CCDC120	5.26e-06	186	161	7	4c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AFF3 MAP3K1 PRDM2 PRKD3 PWWP2B RIPOR1 DNMBP	7.16e-06	195	161	7	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AFF3 MAP3K1 PRDM2 PRKD3 PWWP2B RIPOR1 DNMBP	7.16e-06	195	161	7	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	HIP1 LAMB3 GTF2IRD1 ARFGEF3 HIVEP3 PKHD1 CACNA1H	7.40e-06	196	161	7	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 PPFIBP2 ANO1 TNFRSF11A CASZ1 ARFGEF3 WNK2	8.45e-06	200	161	7	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-5\|TCGA-Brain / Sample_Type by Project: Shred V9	LRIT2 SASH1 PPFIBP2 ACAN FHDC1 UNC79	1.07e-05	137	161	6	a7c76201b8901b2ef7ebbb4dfe0cec0dc4534ef5
ToppCell	remission-unassigned\|remission / disease stage, cell group and cell class	TACC2 TNFRSF11A FARS2 CCDC120 CACNA1H DDX43	2.07e-05	154	161	6	4130769829b838cc8a075c87ff6c187f0f507f8b
ToppCell	remission-unassigned\|World / disease stage, cell group and cell class	TACC2 TNFRSF11A FARS2 CCDC120 CACNA1H DDX43	2.15e-05	155	161	6	d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F RNF31 MEX3D SNX19 STOX2 ANGPT4	2.31e-05	157	161	6	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F RNF31 MEX3D SNX19 STOX2 ANGPT4	2.31e-05	157	161	6	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	LRIT2 AFF3 ARFGEF3 XKR7 DGKK UNC79	2.66e-05	161	161	6	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO9B AFF3 MAP3K1 PRDM2 PRKCB RIPOR1	2.86e-05	163	161	6	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB2 HMMR CLCN2 CD27 DDX43 TACC3	3.06e-05	165	161	6	ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCP11 CCDC168 HMMR ZNF707 FARS2 TACC3	3.38e-05	168	161	6	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STXBP5 BRCA1 CD27 HSH2D TACC3 USP3	3.74e-05	171	161	6	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKN1C FLNC CYB5RL TNFRSF11A STOX2 CRAMP1	3.99e-05	173	161	6	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD SEMA4F HMMR BCL6B ARHGEF3 TACC3	4.67e-05	178	161	6	ea10117026021c959ffc871fc377cdb3e161d264
ToppCell	CTRL-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	SLC9A9 AFF3 CHD3 TNFRSF11A ZNF608 PRKCB	5.29e-05	182	161	6	ee137574b8f0e684a4a7cb26226877c471cae433
ToppCell	IPF-Lymphoid-B\|IPF / Disease state, Lineage and Cell class	AFF3 ZHX2 PRDM2 CD27 PRKCB HSH2D	5.45e-05	183	161	6	e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C SOX10 CDK18 HIP1 VWA1 ZHX2	5.62e-05	184	161	6	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 ANO1 LAMB3 SHROOM2 ARFGEF3 CCDC120	5.62e-05	184	161	6	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 ANO1 LAMB3 SHROOM2 ARFGEF3 CCDC120	5.62e-05	184	161	6	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C SOX10 CDK18 HIP1 VWA1 ZHX2	5.79e-05	185	161	6	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	TACC2 ACSS2 ARFGEF3 STOX2 ZNF608 WNK2	5.79e-05	185	161	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	IL12RB2 SLC9A9 TSHZ3 TNFRSF11A MAP3K1 PRKCB	5.79e-05	185	161	6	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	JCAD SASH1 VWA1 PPP1R26 TDRD6 MOCS1	5.96e-05	186	161	6	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 LAMB3 GTF2IRD1 C6orf132 HIVEP3 PKHD1	6.14e-05	187	161	6	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRR16 SLC6A5 CACNA1H MOCS1 WNK2 TBX5	6.14e-05	187	161	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 LAMB3 GTF2IRD1 C6orf132 HIVEP3 PKHD1	6.14e-05	187	161	6	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 LAMB3 GTF2IRD1 C6orf132 HIVEP3 PKHD1	6.14e-05	187	161	6	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C SOX10 CDK18 HIP1 VWA1 ZHX2	6.14e-05	187	161	6	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	VPS54 ABCC6 FARS2 PKHD1 SERPINF2 WNK2	6.14e-05	187	161	6	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AFF3 TACC2 GTF2IRD1 CASZ1 WNK2 TBX5	6.33e-05	188	161	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C SOX10 CDK18 HIP1 VWA1 ZHX2	6.33e-05	188	161	6	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AFF3 ANO1 C2CD2 PRR16 ACAN WNK2	6.33e-05	188	161	6	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 ANO1 TACC2 PRR16 ANGPT4 TBX5	6.33e-05	188	161	6	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKN1C SOX10 CDK18 HIP1 VWA1 ZHX2	6.52e-05	189	161	6	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AFF3 PRR16 ACAN ANGPT4 CACNA1H WNK2	6.52e-05	189	161	6	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FLNC ADGRB2 ANO1 VWA1 NACAD MOCS1	6.52e-05	189	161	6	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AFF3 PRR16 ACAN ANGPT4 CACNA1H WNK2	6.52e-05	189	161	6	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 PPFIBP2 ANO1 PRR16 ANGPT4 ADAMTSL4	6.52e-05	189	161	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 SLC9A9 AMPD2 PPFIBP2 TNFRSF11A DNMBP	6.71e-05	190	161	6	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AFF3 TACC2 ACSS2 ABCC6 ARFGEF3 FHDC1	6.71e-05	190	161	6	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AFF3 TACC2 ACSS2 ARFGEF3 STOX2 FHDC1	6.91e-05	191	161	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	AFF3 TACC2 ABCC6 ARFGEF3 STOX2 FHDC1	6.91e-05	191	161	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL12RB2 BNC2 TSPOAP1 PRKCB HSH2D ARHGEF3	6.91e-05	191	161	6	6345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD SASH1 AFF3 CASZ1 BCL6B ARHGEF3	7.11e-05	192	161	6	7197e401e563441ab94815f7619e032ebef9e586
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	AFF3 TACC2 ACSS2 ARFGEF3 STOX2 FHDC1	7.11e-05	192	161	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AFF3 TACC2 ACSS2 ARFGEF3 ITPKC FHDC1	7.11e-05	192	161	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	droplet-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 ZNF707 PRKD3 PRKCB ADAMTSL4	7.25e-05	119	161	5	018162114bc22a9780fded5887f1f78211851700
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SASH1 TACC2 VWA1 ABCC6 DLX4 PLOD2	7.31e-05	193	161	6	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JCAD HMMR ARFGEF3 BCL6B FAM124B CBX2	7.31e-05	193	161	6	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	BNC2 SLC9A9 TSHZ3 MYO9B TNFRSF11A PRKCB	7.31e-05	193	161	6	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL12RB2 BNC2 TSPOAP1 PRKCB HSH2D ARHGEF3	7.31e-05	193	161	6	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	AFF3 PRDM2 PRKD3 ZNF608 PRKCB RIPOR1	7.53e-05	194	161	6	5cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDKN1C SLC9A9 MYO9B FAM117B MAP3K1 PRKCB	7.53e-05	194	161	6	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDKN1C SLC9A9 MYO9B FAM117B MAP3K1 PRKCB	7.53e-05	194	161	6	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AFF3 MAP3K1 PRDM2 PRKD3 PWWP2B RIPOR1	7.53e-05	194	161	6	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HIP1 PRR16 ACAN CACNA1H MOCS1 TBX5	7.96e-05	196	161	6	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C SOX10 CDK18 VWA1 NACAD ARFGEF3	8.19e-05	197	161	6	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BNC2 SLC9A9 TSHZ3 PRR16 PRKCB TBX5	8.19e-05	197	161	6	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX10 CDK18 SASH1 VWA1 NACAD ARFGEF3	8.66e-05	199	161	6	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX10 CDK18 SASH1 VWA1 NACAD ARFGEF3	8.66e-05	199	161	6	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNC RNF31 POM121C SLC4A2 RIPOR1 SPOCD1	8.66e-05	199	161	6	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	JCAD PCGF2 VWA1 SHROOM2 BCL6B STOX2	8.66e-05	199	161	6	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX10 CDK18 SASH1 VWA1 NACAD ARFGEF3	8.66e-05	199	161	6	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX10 CDK18 SASH1 VWA1 NACAD ARFGEF3	8.66e-05	199	161	6	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLF11 THAP10 SCAND1 VWA1 CLCN2 PKHD1	8.66e-05	199	161	6	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 PPFIBP2 ANO1 TNFRSF11A CASZ1 WNK2	8.90e-05	200	161	6	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TACC2 CASZ1 ARFGEF3 STOX2 ARHGEF3 WNK2	8.90e-05	200	161	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C SOX10 CDK18 VWA1 NACAD ARFGEF3	8.90e-05	200	161	6	0bfd41c12887479ceb62c3db0a3c3ba5007eb62b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C SOX10 CDK18 VWA1 NACAD ARFGEF3	8.90e-05	200	161	6	159377d904394d91e09913131e9a93e08189955a
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	JCAD SASH1 BPTF ZNF608 ARHGEF3 FAM124B	8.90e-05	200	161	6	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TSHZ3 ANO1 TACC2 PRR16 ANGPT4 TBX5	8.90e-05	200	161	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Tracheal-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 ANO1 MESP1 ARFGEF3 ITPKC WNK2	8.90e-05	200	161	6	a3e044468de437948b63c517e0a4773cc247c906
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANO1 TACC2 CASZ1 ARFGEF3 STOX2 WNK2	8.90e-05	200	161	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SEMA4F CYB5RL ZHX2 RPTOR TDRD6	9.86e-05	127	161	5	9071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	C2CD2 SERPINF2 MACIR CBX2 BAHCC1	1.41e-04	137	161	5	3f4746fb6fc36c90a8cd25725531a1503422cfbf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TCP11 TACC2 GTF2IRD1 CASZ1 ARHGEF3	1.66e-04	142	161	5	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	Severe-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HIP1 AFF3 CHD3 ZNF608 BAHCC1	1.83e-04	145	161	5	a24cad86509208bc7267b02ef1d1b0a25a2a7043
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD3 ITPKC SALL1 BTBD7 MACIR	2.02e-04	148	161	5	b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD3 ITPKC SALL1 BTBD7 MACIR	2.02e-04	148	161	5	ba277c898678dd36f8dc1d681301c71901b89055
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN1C CHD3 UPF3B ACSS2 DCP1B	2.08e-04	149	161	5	65778f19599b4955c0a16f0121237656449431fb
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCGF2 UNCX DMRT3 NANOS3	2.12e-04	81	161	4	1a22222f2b4ab30f7aa31820029c267a0f2190ec
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|World / disease group, cell group and cell class (v2)	IL12RB2 TNFRSF11A ACAN ETNK2 MTMR2	2.35e-04	153	161	5	aff5c8ab1fb4ebc324cec02cf562b7484bb10db8
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDKN1C BNC2 FLNC CXXC4 TBX5	2.50e-04	155	161	5	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	POM121C C6orf132 ZNF512B PRR16 CD27	2.58e-04	156	161	5	fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO1 MESP1 PRR16 CXXC4 SERPINF2	2.58e-04	156	161	5	60f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pro-B\|bone_marrow / Manually curated celltypes from each tissue	AFF3 VWA1 RIPOR1 CBX2 BAHCC1	2.58e-04	156	161	5	b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F TSPOAP1 HMMR TACC3 CBX2	2.73e-04	158	161	5	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|368C / Donor, Lineage, Cell class and subclass (all cells)	TSPOAP1 DBF4B TNFRSF11A HMMR STOX2	2.89e-04	160	161	5	bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA4F IL12RB2 SLC9A9 CACNA1H UNC79	2.89e-04	160	161	5	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	AFF3 SHROOM2 NACAD ZNF608 FAM124B	3.15e-04	163	161	5	7f61483eeb1fde21843c6391468e13cb0cc2a89f
Drug	Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	HIP1 PCGF2 RNF31 CEP164 SLC4A2 ZNF512B ZNF750 ETNK2 PRRC2B BAHCC1	1.25e-06	196	159	10	5341_UP
Drug	cox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A	JCAD HTR1A CASP4 ABCC6 ACAN ANGPT4 CXXC4 SLC6A5 RIPOR1	1.01e-05	196	159	9	253_UP
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A	CDK18 INTS1 CHD3 RIPOR1 SRRM2 BBC3 PRRC2B IQCE BAHCC1	1.05e-05	197	159	9	2766_UP
Drug	Tropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A	DSCAM LAMB3 FNDC3A CHD3 HIVEP3 BTBD7 RIPOR1 MOCS1 BAHCC1	1.10e-05	198	159	9	3569_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A	MYO9B SNX19 SLC4A2 ZNF512B FARS2 RIPOR1 BBC3 MACIR PRRC2B	1.14e-05	199	159	9	3403_DN
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	BNC2 HTR1A KLF14 POM121C SNX19 HIVEP3 BPTF ACAN RPTOR PKHD1 UNC79	3.39e-06	364	153	11	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	body fat percentage	BNC2 HTR1A KLF14 POM121C SNX19 HIVEP3 BPTF ACAN RPTOR PKHD1 UNC79 PRRC2B	9.83e-06	488	153	12	EFO_0007800
Disease	mean arterial pressure	TCF20 MYO9B STXBP5 POM121C CASZ1 PRKD3 HIVEP3 RPTOR PKHD1 NANOS3 ARHGEF3 BAHCC1	1.23e-05	499	153	12	EFO_0006340
Disease	Apnea	HTR1A SLC6A5	7.99e-05	3	153	2	C0003578
Disease	body surface area	LRRC66 BNC2 UNCX MYO9B ACSS2 ZHX2 ZNF608 ACAN RPTOR PKHD1 UNC79 PPP6R3	1.40e-04	643	153	12	EFO_0022196
Disease	visceral adipose tissue measurement	BNC2 HTR1A ADGRB2 POM121C HIVEP3 BPTF RPTOR PKHD1 ARHGEF3 UNC79	2.17e-04	481	153	10	EFO_0004765
Disease	Choledochal Cyst, Type I	SLC4A2 PKHD1	2.64e-04	5	153	2	C0009439
Disease	primary hyperaldosteronism (is_implicated_in)	CLCN2 CACNA1H	2.64e-04	5	153	2	DOID:446 (is_implicated_in)
Disease	Choledochal Cyst, Type II	SLC4A2 PKHD1	2.64e-04	5	153	2	C1257796
Disease	Choledochal Cyst, Type III	SLC4A2 PKHD1	2.64e-04	5	153	2	C1257797
Disease	Choledochal Cyst, Type IV	SLC4A2 PKHD1	2.64e-04	5	153	2	C1257798
Disease	Choledochal Cyst, Type V	SLC4A2 PKHD1	2.64e-04	5	153	2	C1257799
Disease	procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 measurement	ARHGEF3 PLOD2	2.64e-04	5	153	2	EFO_0802912
Disease	Choledochal Cyst	SLC4A2 PKHD1	2.64e-04	5	153	2	C0008340
Disease	Pure gonadal dysgenesis 46,XY	MAP3K1 CBX2	3.95e-04	6	153	2	cv:C2936694
Disease	Idiopathic generalized epilepsy	CLCN2 CACNA1H	3.95e-04	6	153	2	cv:C0270850
Disease	Prostate cancer, familial	MYO9B PPFIBP2 CHD3 BRCA1	4.62e-04	69	153	4	C2931456
Disease	Swyer Syndrome	MAP3K1 CBX2	5.51e-04	7	153	2	C2936694
Disease	alcohol use disorder (implicated_via_orthology)	ACSS2 ANGPT4 PRKCB SRRM2 PHF10 UNC79	5.57e-04	195	153	6	DOID:1574 (implicated_via_orthology)
Disease	Abnormality of the skeletal system	PCGF2 INTS1	7.33e-04	8	153	2	C4021790
Disease	Gonadal Dysgenesis, 46,XY	MAP3K1 CBX2	7.33e-04	8	153	2	C0018054
Disease	hematocrit	JCAD UNCX AFF3 CHD3 ABCC6 CEP164 SLC4A2 SALL1 DGKK PKHD1 ASXL2 ARHGEF3 BAHCC1 TBX5	8.18e-04	1011	153	14	EFO_0004348
Disease	forced expiratory volume	JCAD BNC2 TSHZ3 DSCAM TCP11 AFF3 ZHX2 CASZ1 MAP3K1 ACAN USP3 PRRC2B	8.74e-04	789	153	12	EFO_0004314
Disease	Autosomal Recessive Polycystic Kidney Disease	SLC4A2 PKHD1	9.39e-04	9	153	2	C0085548
Disease	age at menarche	HIP1 DSCAM AFF3 KLF14 FNDC3A PRDM2 BRCA1 RPTOR ASCC3 UNC79	1.11e-03	594	153	10	EFO_0004703
Disease	bone morphogenetic protein 7 measurement	CHRDL2 ARHGEF3	1.17e-03	10	153	2	EFO_0020187
Disease	cognitive function measurement	HTR1A TCF20 DSCAM DBF4B AFF3 PRR16 STOX2 CLCN2 ZNF608 MTMR2 PKHD1 MAST1 CACNA1H ASXL2 FHDC1 MACIR WNK2	1.28e-03	1434	153	17	EFO_0008354
Disease	46,XY partial gonadal dysgenesis	MAP3K1 DMRT3	1.42e-03	11	153	2	C4510744
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	SLC4A2 PKHD1	1.42e-03	11	153	2	DOID:0110861 (biomarker_via_orthology)
Disease	S-warfarin to R-warfarin ratio measurement	JCAD SLC9A9 CHRDL2 ARFGEF3	1.53e-03	95	153	4	EFO_0803331
Disease	age-related hearing impairment	BNC2 HTR1A SASH1 ADGRB2 ACAN PRR14L SPOCD1	1.56e-03	324	153	7	EFO_0005782
Disease	bronchopulmonary dysplasia	HTR1A STXBP5 HIVEP3	1.65e-03	45	153	3	MONDO_0019091
Disease	motor neuron disease (implicated_via_orthology)	VPS54 VWA1	1.70e-03	12	153	2	DOID:231 (implicated_via_orthology)
Disease	sexual dimorphism measurement	LRRC66 MYO9B TCP11 KLF14 ACSS2 GTF2IRD1 CEP164 BPTF ZNF608 ACAN ASXL2 TACC3 SPOCD1 PPP6R3	1.90e-03	1106	153	14	EFO_0021796
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	IL12RB2 AFF3 TNFRSF11A HIVEP3 MACIR	1.97e-03	170	153	5	EFO_0000685, EFO_0007791, EFO_0007837
Disease	myopathy (implicated_via_orthology)	FLNC CLCN2 MTMR2	1.99e-03	48	153	3	DOID:423 (implicated_via_orthology)
Disease	red blood cell density measurement	KLF11 UNCX AFF3 ZNF217 ABCC6 CASZ1 PRKD3 SALL1 PKHD1 ARHGEF3 USP3 MACIR	2.19e-03	880	153	12	EFO_0007978
Disease	cognitive function measurement, self reported educational attainment	HTR1A TCF20 AFF3 CLCN2 MTMR2 PKHD1 MACIR	2.61e-03	355	153	7	EFO_0004784, EFO_0008354
Disease	Antihypertensive use measurement	HTR1A MYO9B CASZ1 NANOS3 CACNA1H ARHGEF3	2.67e-03	265	153	6	EFO_0009927
Disease	rheumatoid arthritis	IL12RB2 SLC9A9 AFF3 TNFRSF11A GTF2IRD1 PRKCB ARHGEF3 MACIR	2.92e-03	462	153	8	EFO_0000685
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	JCAD BNC2 TSHZ3 TCF20 AFF3 ADGRB2 TACC2 BPTF ASCC3 UNC79 PRRC2B	3.15e-03	801	153	11	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	reticulocyte count	BNC2 MYO9B KLF14 FAM117B ZNF217 ZHX2 MAP3K1 MAST1 ASXL2 FHDC1 ARHGEF3 SPOCD1 USP3	3.19e-03	1045	153	13	EFO_0007986
Disease	Polydactyly	CEP164 C2CD3 SALL1 TBX5	3.27e-03	117	153	4	C0152427
Disease	reticulocyte measurement	BNC2 MYO9B AFF3 KLF14 ZNF217 MAP3K1 MAST1 ASXL2 FHDC1 ARHGEF3 SPOCD1 USP3 MACIR	3.41e-03	1053	153	13	EFO_0010700
Disease	ankle injury	HIP1 PRR16 PRKCB	3.59e-03	59	153	3	EFO_1002021
Disease	PROSTATE CANCER, HEREDITARY, 1	MYO9B PPFIBP2 CHD3	3.77e-03	60	153	3	C4722327
Disease	neuroimaging measurement	AFF3 THAP10 TACC2 ZHX2 POM121C MAP3K1 DMRT3 BRCA1 MTMR2 PKHD1 TACC3 WNK2 BAHCC1	3.86e-03	1069	153	13	EFO_0004346
Disease	FEV/FEC ratio	JCAD BNC2 TSHZ3 TCP11 AFF3 ANO1 GTF2IRD1 MAP3K1 HIVEP3 GID4 ACAN RIPOR1 USP3 TBX5	4.84e-03	1228	153	14	EFO_0004713
Disease	Prostatic Neoplasms	RNF31 PPFIBP2 CHD3 CASZ1 MAP3K1 SLC4A2 BRCA1 MACIR ZMYM3	4.98e-03	616	153	9	C0033578
Disease	Malignant neoplasm of prostate	RNF31 PPFIBP2 CHD3 CASZ1 MAP3K1 SLC4A2 BRCA1 MACIR ZMYM3	4.98e-03	616	153	9	C0376358
Disease	cystatin C measurement	BNC2 UNCX FNDC3A FAM117B SALL1 PKHD1 TMEM266	5.13e-03	402	153	7	EFO_0004617
Disease	Global developmental delay	PCGF2 TCF20 INTS1 CHD3	5.16e-03	133	153	4	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
GAAERSVCTDKPSPG	ADGRB2	1516	O60241
SVCTDKPSPGERPSL	ADGRB2	1521	O60241
CTSYRGVPASKPEPA	AFF3	261	P51826
GFPACLPAPKSSTDS	LINC01547	166	P58512
RRPAKGADSFCTPEP	SLC4A2	6	P04920
TSGRCAKEAAGPPEP	BAHCC1	316	Q9P281
NCSLELPPASGPAKD	ARHGEF3	16	Q9NR81
APSSPIPRCSGESEQ	ADAMTSL4	356	Q6UY14
VGLSATPAPKSCPER	CD27	16	P26842
TALKSPPGVCSRDPT	SERPINF2	61	P08697
SPQKFSPEGDLCSSP	BNC2	816	Q6ZN30
AEGTRCTDPPAGKPA	CASZ1	6	Q86V15
PPESGESTDALKLCP	CASP4	96	P49662
GRDPPQECSTFSPTD	CDK18	51	Q07002
PPPDTLASAGDFLCT	BBC3	246	Q96PG8
ATPGPASKCSPCERS	AJM1	21	C9J069
ETAPPPLCASRNSKA	BTBD11	776	A6QL63
ASPPPKECDQGTLSA	DNMBP	1406	Q6XZF7
SCVFGAEKSPDDPRP	AP5S1	26	Q9NUS5
GDSTSQSPPIKRSCP	ACSS2	261	Q9NR19
PGPSRCRSDSPAVAA	AMPD2	36	Q01433
PSEGRSPVGCLSETP	BPTF	651	Q12830
CPLPGRDASKAVFPD	DLX4	6	Q92988
PKAKAADPPDGFCSS	DISP2	1271	A7MBM2
ASSSCFSPGPPLEVK	CDK13	76	Q14004
SCRQEKAPSPTGPAL	ASXL2	826	Q76L83
RGAGKSEPSPSCSPS	NANOS3	156	P60323
ASPKKPGCSSPAAAV	RIMBP3B	11	A6NNM3
ASPKKPGCSSPAAAV	RIMBP3C	11	A6NJZ7
GRCTPKSSEPAPATL	TSPOAP1	576	O95153
THPEGACPSKEPSAD	ITPKC	206	Q96DU7
DSSEEGLPRPRSPCS	IQCE	501	Q6IPM2
VSVDSEPSCKGGLPR	FHDC1	836	Q9C0D6
LAPGPCPEATSESAT	DGKK	61	Q5KSL6
ATADAASPFPACKPV	INTS1	1566	Q8N201
APSCTPAAPQSKDGS	LRIT2	506	A6NDA9
GGPSRAALSPKCSDP	JCAD	711	Q9P266
ESRGSDPKPENPACP	IL12RB2	771	Q99665
LAPSASGPPVCKSSE	CCDC120	381	Q96HB5
EKAAASASCREPPGP	ETNK2	31	Q9NVF9
PGKAEAEKPRCSSTP	MACIR	26	Q96GV9
SPPSSGEACREEKGL	NAA10	186	P41227
PFSEKGPPSVCETRS	DDIAS	976	Q8IXT1
PKSPFRVGVTEGCDP	FLNC	1336	Q14315
RGPESQSCPSKLNPE	CYB5RL	61	Q6IPT4
KPPSASSAPALAREC	MEX3D	586	Q86XN8
AVLPAASPCSSPKTG	PRKD3	21	O94806
SCESLGSQPAAARPP	MTMR2	6	Q13614
CPGADKGPASDDPRS	PRKCB	86	P05771
KACPDSLGSPAPSHA	ANO1	966	Q5XXA6
PGHSEISSTRCPKAP	CHRDL2	321	Q6WN34
ATSSCPPKSPLGETR	HSH2D	186	Q96JZ2
GEAAKSPPTICQPDA	PPFIBP2	436	Q8ND30
PPCSAEVPSDPDKAA	LRRC66	856	Q68CR7
ESPGGAEACTPPRAT	MAST1	1361	Q9Y2H9
PVTQPCPGESARAAS	MOCS1	26	Q9NZB8
PDKQAPGSDSQPRCV	SMPD4	451	Q9NXE4
PRTPCVGDKDSSPGV	ACAN	541	P16112
NPCLGADSEKPSSIP	PLOD2	21	O00469
SLPPCPESAGAATTE	POM121C	586	A8CG34
VRTECPPPAGASAAS	GID4	86	Q8IVV7
CESVSDKAPSPATLP	PCGF2	256	P35227
APLKRFNDPSGCAPS	HMMR	6	O75330
CDSDPATPGAQSPKD	PHF10	16	Q8WUB8
RLCPPDDSTKSGDSA	UPF3B	451	Q9BZI7
PGVERSSPSKCPSLD	BRCA1	1491	P38398
RAPEPDCPGELKATA	C6orf132	356	Q5T0Z8
DCPGELKATAPASPR	C6orf132	361	Q5T0Z8
STPGAANKCDPSTPA	DCP1B	361	Q8IZD4
KAPPDAAPGLVASNC	CEFIP	971	Q711Q0
ELPEPSGSPTSDRCA	FAM124B	296	Q9H5Z6
PCPQARLPSGDEASS	BCL6B	221	Q8N143
PPTPASKRDCVKGSA	CBX2	421	Q14781
ASTAQESCPPKPPRA	C2CD2	246	Q9Y426
GEAPLPCDDKLTTSP	C2CD3	1861	Q4AC94
RSAPEKSSGDVPAPC	CDKN1C	281	P49918
PKKPEGTCPAAESRT	DBF4B	206	Q8NFT6
PDVAKSKGCFTPESP	DMRT3	181	Q9NQL9
CTSKPATPAPSEKGE	CHD3	1551	Q12873
DAPGSPLACTEPSRT	GAS2L1	616	Q99501
FSEKCDITTAPGPPD	FNDC3A	746	Q9Y2H6
SSPEKRSPSAPVCKA	FAM117B	186	Q6P1L5
KEIGDCAPAPGAPST	ARFGEF3	1371	Q5TH69
PCLEKTPAEGRDSPT	CRAMP1	521	Q96RY5
DSQRLGKAGCPPEPS	CXXC4	6	Q9H2H0
AGPTPCAPASFERKN	HTR1A	311	P08908
VARACPQSAKPPSGS	BAHD1	531	Q8TBE0
KSEPCPPGPEVSRDS	ANGPT4	51	Q9Y264
KAAPPDCTSTAGLGR	BTBD7	821	Q9P203
EPVPSSPCRAKGTSV	KLF11	161	O14901
EAPRASSGFSDPIPC	KLF14	106	Q8TD94
ADRCAPKPGASAGPS	LAMB3	256	Q13751
GEAPTCKSPSCEPKT	KRTAP24-1	66	Q3LI83
PAGSAVPAQSRPCVD	C4orf48	36	Q5BLP8
RPVACPKGDSGESSA	ENDOV	266	Q8N8Q3
DPCKSGSEPKSPEGR	CCDC168	2016	Q8NDH2
KQEAPSCPLAPSDLG	GTF2IRD1	271	Q9UHL9
GDQKPPASLRSSPCA	CACNA1H	1116	O95180
SRDRPSCAPSASIPK	PWWP2B	301	Q6NUJ5
DCPEGSIPDTPKSAD	SALL1	831	Q9NSC2
GEKRPIPNPTCTFDD	DDX43	231	Q9NXZ2
ASKDDSSPPSLGPDC	PRDM2	441	Q13029
PADGTRSPSPCKSLE	PRDM2	906	Q13029
PCLLGAPRKAQDPSS	PRR14L	1486	Q5THK1
SSPAAAEPGEKRAPA	MAP3K1	136	Q13233
SGICRFTASPPKPQD	DSCAM	1866	O60469
TLAELPGSPPEKCDS	RTN3	446	O95197
AVATSPPGAIPKEAC	TACC3	246	Q9Y6A5
GRSECDSSPEPKALP	SRRM2	1476	Q9UQ35
REESPDKPGSPCASC	TDRD6	306	O60522
ADVSSLCPKEPGERP	SEMA4F	556	O95754
SSPCSPPARLGLDQK	SLC9A9	596	Q8IVB4
DLPCDSKPESALGAP	TBX5	21	Q99593
EAERPGVGSCKLSSP	SLC6A5	71	Q9Y345
NPCPETGAAFPSKAT	ABCC6	201	O95255
ASPKKPGCSSPAAAV	RIMBP3	11	Q9UFD9
EVDKPPCTFSTPSRG	PIWIL2	166	Q8TC59
SSCPAEGPPAASKTK	PRR16	11	Q569H4
PERNCVGSSLPEASP	SCAND1	31	P57086
GATTCLRAPPEPADS	HIP1	706	O00291
SEEKLSCFPPRVPGD	SHROOM2	261	Q13796
RCKPEPAHGSAPTAL	PPP1R26	171	Q5T8A7
EGSTKPATPCRPSEA	PPP1R26	316	Q5T8A7
VSSPNPGPRDSCTFK	PKHD1	116	P08F94
CADTSAPEPARSLGP	RNF217	61	Q8TC41
PPSDKDCGRSLVSSP	MESP1	26	Q9BRJ9
PEDRCKSPTSGSSSP	STXBP5	706	Q5T5C0
DTSPGCAAPSQAPFK	SPATC1L	101	Q9H0A9
EGGSLTPVRDSPCTP	RPTOR	701	Q8N122
REQAPSPPAACEKGK	CEP164	526	Q9UPV0
GKPESCAVTPRFPKS	ASCC3	2096	Q8N3C0
SLFCGSPPPEAASEK	CLCN2	726	P51788
SAPLPSSCGDPEKQR	RNF31	466	Q96EP0
RESALSAKACTPDGP	VWA1	411	Q6PCB0
SPCKSPAPEAALGAQ	ZNF750	136	Q32MQ0
SEGRSCKPETSGPPQ	TCP11	16	Q8WWU5
AAPERTDAKPTAFPC	ZNF707	136	Q96C28
RKASEPCGPPADAIT	XKR7	456	Q5GH72
SHPKTPADTLPGRCE	STOX2	726	Q9P2F5
GPTDEAGSECPFPRK	SPOCD1	1201	Q6ZMY3
GSEEPRCLSPGSAPS	SOX10	16	P56693
QKAESRSPSCSPGPA	HIVEP3	2136	Q5T1R4
CTSDSKDPSLRPAQP	PRRC2B	246	Q5JSZ5
LAPDTSKSCDPPGVT	SASH1	791	O94885
VKRGSPASPTSPSDC	SASH1	1021	O94885
LTSPDQPRGPACDAS	TACC2	756	O95359
GDRVEASTPSCPDPA	TACC2	1926	O95359
ASTPSCPDPAKDLSR	TACC2	1931	O95359
SSKDLPSPDSRNCPA	TCF20	1316	Q9UGU0
GIFSKARDPAPCPAS	SNX19	266	Q92543
SQENSPSPPRDGCKD	TSHZ3	666	Q63HK5
PLCFDPGSPASDKTE	ZNF512B	56	Q96KM6
VGSEPAKDCLPAKPS	ZHX2	751	Q9Y6X8
CIAPDSAKFPNGSPS	USP3	11	Q9Y6I4
TPPNCAAEDIKASPS	ZNF608	481	Q9ULD9
CRTKADVTPPPDGST	ZNF217	641	O75362
EGTADPVACPRGSSP	ZNF648	46	Q5T619
TRTPGTVEDGSAPCP	TP53TG3	31	Q9ULZ0
APCTPAPEAASTRDA	WNK2	1491	Q9Y3S1
SEAAPGPVSCTRPRA	THAP10	121	Q9P2Z0
PPAAECATQRAPGSV	FARS2	36	O95363
KHSDPTLPGTDSLPC	RIPOR1	696	Q6ZS17
EAKCAAPRPPSSSPE	PPP6R3	841	Q5H9R7
PIPQSGDPADATRCS	ZMYM3	396	Q14202
CSTAREEPSSEPGPS	TMEM266	411	Q2M3C6
LPDVCPKEPTGDSHS	VPS54	36	Q9P1Q0
DAVCSSSLPARKPPN	TNFRSF11A	191	Q9Y6Q6
QPRPGRPADKDAASC	UNCX	296	A6NJT0
SSKPEELPEFSCGSP	UNC79	1726	Q9P2D8
SSLDRGCPDAPAPTS	NACAD	1161	O15069
SKPCGSPRVQEKPDS	MYO9B	1276	Q13459