Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	RasGEFN	RASGRP1 RASGRF2 SOS1	4.20e-05	20	64	3	SM00229
Domain	RasGEF_N	RASGRP1 RASGRF2 SOS1	4.88e-05	21	64	3	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RASGRP1 RASGRF2 SOS1	5.64e-05	22	64	3	IPR000651
Domain	RASGEF_NTER	RASGRP1 RASGRF2 SOS1	5.64e-05	22	64	3	PS50212
Domain	RASGEF	RASGRP1 RASGRF2 SOS1	9.43e-05	26	64	3	PS00720
Domain	Choline_transpo	SLC44A5 SLC44A2	1.15e-04	5	64	2	PF04515
Domain	Choline_transptr-like	SLC44A5 SLC44A2	1.15e-04	5	64	2	IPR007603
Domain	RASGEF_CAT	RASGRP1 RASGRF2 SOS1	1.32e-04	29	64	3	PS50009
Domain	RasGEF	RASGRP1 RASGRF2 SOS1	1.46e-04	30	64	3	PF00617
Domain	-	RASGRP1 RASGRF2 SOS1	1.46e-04	30	64	3	1.10.840.10
Domain	Ras_GEF_dom	RASGRP1 RASGRF2 SOS1	1.46e-04	30	64	3	IPR023578
Domain	RASGEF_cat_dom	RASGRP1 RASGRF2 SOS1	1.46e-04	30	64	3	IPR001895
Domain	RasGEF	RASGRP1 RASGRF2 SOS1	1.46e-04	30	64	3	SM00147
Domain	Methyltransf_12	FASN METTL6	1.72e-04	6	64	2	PF08242
Domain	Methyltransf_12	FASN METTL6	1.72e-04	6	64	2	IPR013217
Domain	Ras_G-nucl-exch_fac_CS	RASGRF2 SOS1	1.02e-03	14	64	2	IPR019804
Domain	aa-tRNA-synth_II	GARS1 DARS1	1.71e-03	18	64	2	IPR006195
Domain	AA_TRNA_LIGASE_II	GARS1 DARS1	1.71e-03	18	64	2	PS50862
Domain	GPCR_3	GRM3 GPR179	2.33e-03	21	64	2	IPR000337
Domain	7tm_3	GRM3 GPR179	2.55e-03	22	64	2	PF00003
Domain	G_PROTEIN_RECEP_F3_2	GRM3 GPR179	2.55e-03	22	64	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GRM3 GPR179	2.55e-03	22	64	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GRM3 GPR179	2.55e-03	22	64	2	PS00979
Domain	G_PROTEIN_RECEP_F3_4	GRM3 GPR179	2.55e-03	22	64	2	PS50259
Domain	GPCR_3_C	GRM3 GPR179	2.55e-03	22	64	2	IPR017978
Domain	AMP-binding_CS	ACSL6 ACSM5	3.56e-03	26	64	2	IPR020845
Domain	AMP_BINDING	ACSL6 ACSM5	4.13e-03	28	64	2	PS00455
Domain	FYVE	ZFYVE9 PLEKHF1	4.42e-03	29	64	2	PF01363
Domain	FYVE	ZFYVE9 PLEKHF1	4.42e-03	29	64	2	SM00064
Domain	AMP-binding	ACSL6 ACSM5	4.73e-03	30	64	2	PF00501
Domain	AMP-dep_Synth/Lig	ACSL6 ACSM5	4.73e-03	30	64	2	IPR000873
Domain	Znf_FYVE-rel	ZFYVE9 PLEKHF1	6.04e-03	34	64	2	IPR017455
Pubmed	Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.	RASGRP1 SOS1	3.44e-06	2	65	2	17283063
Pubmed	Deconstructing Ras signaling in the thymus.	RASGRP1 SOS1	1.03e-05	3	65	2	22586275
Pubmed	Targeted Sos1 deletion reveals its critical role in early T-cell development.	RASGRP1 SOS1	1.03e-05	3	65	2	21746917
Pubmed	Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.	MYCN MED1 MED13	1.57e-05	26	65	3	34506481
Pubmed	The ability of Sos1 to oligomerize the adaptor protein LAT is separable from its guanine nucleotide exchange activity in vivo.	RASGRP1 SOS1	2.06e-05	4	65	2	24222714
Pubmed	Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis.	SLC44A5 SLC44A2	2.06e-05	4	65	2	23651124
Pubmed	RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.	RASGRP1 SOS1	3.43e-05	5	65	2	26005835
Pubmed	A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.	RASGRP1 SOS1	3.43e-05	5	65	2	23209318
Pubmed	Molecular characterization of the family of choline transporter-like proteins and their splice variants.	SLC44A5 SLC44A2	3.43e-05	5	65	2	15715662
Pubmed	Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.	RASGRP1 SOS1	5.13e-05	6	65	2	14764585
Pubmed	The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development.	MED1 MED13	7.18e-05	7	65	2	12093747
Pubmed	Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.	MED1 MED13	1.23e-04	9	65	2	8710870
Pubmed	A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.	MED1 MED13	1.53e-04	10	65	2	12218053
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	FASN LLGL2 ZFYVE9 PATJ EPB41L3	1.53e-04	270	65	5	24366813
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PRR12 FASN SETX ANKRD11 MED13	1.59e-04	272	65	5	31010829
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	CRNKL1 SETX DARS1 PATJ SOS1	1.73e-04	277	65	5	30745168
Pubmed	MED1 is a lipogenesis coactivator required for postnatal adipose expansion.	FASN MED1	1.87e-04	11	65	2	33888555
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABLIM1 SETX SPATA18 USP43 ANKRD11 PATJ EPB41L3 NOS1AP	1.98e-04	861	65	8	36931259
Pubmed	A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.	MED1 MED13	2.24e-04	12	65	2	23563140
Pubmed	The interactome of the prostate-specific protein Anoctamin 7.	FASN GARS1 GFM1	2.51e-04	65	65	3	32176628
Pubmed	A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.	MED1 MED13	2.65e-04	13	65	2	14657022
Pubmed	CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure.	EPB41L3 CNTN1	2.65e-04	13	65	2	15601927
Pubmed	Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex.	GARS1 DARS1	2.65e-04	13	65	2	11829477
Pubmed	CDK8 is a positive regulator of transcriptional elongation within the serum response network.	MED1 MED13	2.65e-04	13	65	2	20098423
Pubmed	MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.	MED1 MED13	2.65e-04	13	65	2	27570068
Pubmed	A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.	MED1 MED13	3.08e-04	14	65	2	10024883
Pubmed	The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.	FASN DARS1 EPB41L3	3.12e-04	70	65	3	30559450
Pubmed	Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.	MED1 MED13	3.56e-04	15	65	2	18418385
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	RNF213 AP1G2 DARS1 SOS1	3.91e-04	183	65	4	23956138
Pubmed	The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.	MED1 MED13	4.06e-04	16	65	2	10882111
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	FASN GARS1 DARS1 PATJ GFM1	4.09e-04	334	65	5	30425250
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ABLIM1 PTPRS MICAL2 TBCK ANKRD11 RNF213 PATJ PRDM15 SLC4A5 ANKH	4.20e-04	1489	65	10	28611215
Pubmed	Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.	MED1 MED13	4.59e-04	17	65	2	10235266
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CRNKL1 ABLIM1 FASN MICAL2 GARS1 DARS1 MED1 PATJ MED13	5.00e-04	1247	65	9	27684187
Pubmed	Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.	MED1 MED13	5.16e-04	18	65	2	10198638
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	MED1 MED13	5.76e-04	19	65	2	16799563
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	ABLIM1 FASN SETX MRPL15 RNF213 DARS1	6.15e-04	558	65	6	27591049
Pubmed	STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.	MED1 MED13	6.39e-04	20	65	2	17967894
Pubmed	Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.	MED1 MED13	6.39e-04	20	65	2	15340084
Pubmed	The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro.	MED1 MED13	7.76e-04	22	65	2	11867769
Pubmed	The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.	LLGL2 PATJ	7.76e-04	22	65	2	27521426
Pubmed	Composite co-activator ARC mediates chromatin-directed transcriptional activation.	MED1 MED13	8.48e-04	23	65	2	10235267
Pubmed	Functional genetic analysis of mouse chromosome 11.	MED1 MED13	8.48e-04	23	65	2	12955145
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CRNKL1 FASN SETX INCENP MICAL2 GARS1 AP1G2 DARS1 EPB41L3	8.94e-04	1353	65	9	29467282
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	FASN PTPRS GARS1 DARS1 EPB41L3 TXNDC11	1.00e-03	613	65	6	22268729
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PRR12 FASN LLGL2 PTPRS ANKRD11 AP1G2 REV3L MED13	1.03e-03	1105	65	8	35748872
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MYCN FASN SETX DARS1 REV3L PRDM15 L3MBTL3	1.08e-03	857	65	7	25609649
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ABCA12 LPCAT4 RNF213 REV3L EPB41L3 NOS1AP SOS1 WDR72	1.10e-03	1116	65	8	31753913
Pubmed	Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.	EPB41L3 ANKH TXNDC11	1.20e-03	111	65	3	21163940
Pubmed	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	RASGRP1 MED1 TXNDC11	1.23e-03	112	65	3	24390342
Pubmed	Biosynthesis of triacylglycerols.	ACSL6 FASN	1.26e-03	28	65	2	8944226
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ABLIM1 EPB41L3 GRM3 CNTN1	1.27e-03	251	65	4	27507650
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	INCENP MED1 EPB41L3 PRDM15 L3MBTL3 MED13	1.30e-03	645	65	6	25281560
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ACSL6 ABLIM1 FASN PTPRS MICAL2 DARS1 EPB41L3 GRM3 CNTN1	1.32e-03	1431	65	9	37142655
Pubmed	A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.	MED1 MED13	1.35e-03	29	65	2	14638676
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FASN MTRES1 GARS1 LPCAT4 SLC44A2 IRAK3 SPG11 EPB41L3 MED13	1.39e-03	1442	65	9	35575683
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	SLC18A2 RGS9 GRM3	1.43e-03	118	65	3	19156168
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ABLIM1 SETX MED1 EPB41L3 L3MBTL3	1.46e-03	444	65	5	34795231
Pubmed	The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.	MED1 MED13	1.54e-03	31	65	2	23322298
Pubmed	Amyotrophic Lateral Sclerosis Overview	SETX SPG11	1.75e-03	33	65	2	20301623
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	ABLIM1 FASN PATJ EPB41L3	1.75e-03	274	65	4	34244482
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRR12 CRNKL1 ABLIM1 SETX GALNT3 ANKRD11 MED1 PATJ MED13	1.80e-03	1497	65	9	31527615
Pubmed	Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.	RGS9 SLC4A5	1.86e-03	34	65	2	33500475
Pubmed	MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.	MED1 MED13	1.86e-03	34	65	2	15989967
Cytoband	15q14	RASGRP1 LPCAT4 SPG11	4.76e-05	49	65	3	15q14
Cytoband	10q25	ABLIM1 SLC18A2	1.08e-04	11	65	2	10q25
Cytoband	Ensembl 112 genes in cytogenetic band chr10q25	ABLIM1 SLC18A2 VWA2	8.71e-04	131	65	3	chr10q25
GeneFamily	Aminoacyl tRNA synthetases, Class II	GARS1 DARS1	1.15e-03	19	48	2	132
GeneFamily	Acyl-CoA synthetase family	ACSL6 ACSM5	2.15e-03	26	48	2	40
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE9 PLEKHF1	3.06e-03	31	48	2	81
GeneFamily	Cyclins\|Mediator complex	MED1 MED13	3.46e-03	33	48	2	1061
GeneFamily	Solute carriers	SLC44A5 SLC18A2 SLC44A2 SLC7A7 SLC4A5	3.84e-03	395	48	5	752
GeneFamily	LIM domain containing	ABLIM1 MICAL2	1.07e-02	59	48	2	1218
Coexpression	GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP	RASGRP1 ABLIM1 FASN MICAL2 SGPP2 ANKH	9.50e-06	200	64	6	M8764
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LLGL2 MICAL2 SGPP2 USP43 PATJ NOS1AP	2.65e-07	181	65	6	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 MICAL2 PATJ VWA2 WDR72	3.21e-07	187	65	6	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	facs-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 LLGL2 ABCA12 LPCAT4 SLC44A2 ANKH	3.86e-07	193	65	6	33437fdb417d78463caee14a9f0e094da1733829
ToppCell	Control-Epithelial_alveolar-AT_1-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SGPP2 AP1G2 EPB41L3 SLC4A5 GPR179	2.07e-06	142	65	5	94e277f038f4006d99ff50222b0f5cf89bc3d46d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC44A5 SGPP2 PATJ GPR179 NOS1AP	5.91e-06	176	65	5	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	ABLIM1 LLGL2 MICAL2 PATJ NOS1AP	7.14e-06	183	65	5	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 SGPP2 PATJ EPB41L3 NOS1AP	7.33e-06	184	65	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 LLGL2 ZFYVE9 MICAL2 PATJ	7.33e-06	184	65	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 LLGL2 ZFYVE9 MICAL2 PATJ	7.33e-06	184	65	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABLIM1 LLGL2 PATJ EPB41L3 NOS1AP	7.53e-06	185	65	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 SGPP2 PATJ EPB41L3 NOS1AP	7.73e-06	186	65	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 MICAL2 PATJ WDR72	7.73e-06	186	65	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 TMEM243 SGPP2 PATJ NOS1AP	7.73e-06	186	65	5	e83718fabb057100835d3357df407f283d23fe16
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 SGPP2 PATJ EPB41L3 NOS1AP	7.93e-06	187	65	5	ff26a533d310126521efe1d05cf8b9d32e524550
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FASN LLGL2 MICAL2 SGPP2 PATJ	8.14e-06	188	65	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LLGL2 MICAL2 SGPP2 PATJ NOS1AP	8.14e-06	188	65	5	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	FASN LLGL2 SGPP2 RNF213 EPB41L3	8.35e-06	189	65	5	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LLGL2 MICAL2 PATJ EPB41L3 NOS1AP	8.57e-06	190	65	5	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 PATJ EPB41L3 SLC7A7 WDR72	8.79e-06	191	65	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 PATJ EPB41L3 SLC7A7 WDR72	8.79e-06	191	65	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	FASN MICAL2 TMEM243 SGPP2 PATJ	9.01e-06	192	65	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYCN LLGL2 GALNT3 PATJ VWA2	9.01e-06	192	65	5	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 PATJ NOS1AP WDR72	9.48e-06	194	65	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 SGPP2 PATJ WDR72	9.48e-06	194	65	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 SGPP2 PATJ WDR72	9.48e-06	194	65	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 SLC44A5 USP43 PATJ	9.48e-06	194	65	5	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 MICAL2 SGPP2 USP43	9.48e-06	194	65	5	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 PATJ NOS1AP WDR72	9.72e-06	195	65	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	9.72e-06	195	65	5	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 PATJ NOS1AP WDR72	9.96e-06	196	65	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	9.96e-06	196	65	5	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 MICAL2 SGPP2 PATJ	9.96e-06	196	65	5	0a34a0009f479384f1994c6f977f942699a132c8
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	9.96e-06	196	65	5	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	9.96e-06	196	65	5	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	9.96e-06	196	65	5	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	RASGRP1 LLGL2 RNF213 SPG11 RGS9	1.02e-05	197	65	5	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 LLGL2 SGPP2 USP43 PATJ	1.02e-05	197	65	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FASN GALNT3 TMEM243 AP1G2 PATJ	1.02e-05	197	65	5	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ACSL6 RASGRP1 ABLIM1 RASGRF2 PATJ	1.02e-05	197	65	5	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ACSL6 RASGRP1 ABLIM1 RASGRF2 PATJ	1.02e-05	197	65	5	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.05e-05	198	65	5	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.05e-05	198	65	5	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.05e-05	198	65	5	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.05e-05	198	65	5	df399674345c45738d765a8354ea8d1484572c34
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.05e-05	198	65	5	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FASN GALNT3 TMEM243 AP1G2 PATJ	1.10e-05	200	65	5	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.10e-05	200	65	5	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_Tem\|COVID-19_Severe / Disease, condition lineage and cell class	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.10e-05	200	65	5	31859b8db7ea17e48b7b54e92f0d76aeb755e7ca
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	RASGRP1 LLGL2 PLEKHF1 RNF213 RGS9	1.10e-05	200	65	5	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	(09)_Ionocytes-(3)_72hpi\|(09)_Ionocytes / shred by cell type and Timepoint	PTPRS GARS1 VWA2 L3MBTL3	2.04e-05	110	65	4	fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SGPP2 ACSM5 EPB41L3 NOS1AP	3.59e-05	127	65	4	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 SLC44A5 LPCAT4 PPM1J	7.79e-05	155	65	4	93513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP1 SLC18A2 REV3L PATJ	9.24e-05	162	65	4	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 SLC44A5 RGS9 NOS1AP	9.92e-05	165	65	4	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	MYCN LLGL2 SLC4A5 ANKH	9.92e-05	165	65	4	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP1 SLC44A5 RGS9 NOS1AP	9.92e-05	165	65	4	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE9 SLC18A2 USP43 IRAK3	1.09e-04	169	65	4	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE9 SLC18A2 USP43 IRAK3	1.09e-04	169	65	4	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	control-dn_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RASGRP1 SGPP2 L3MBTL3 ANKH	1.11e-04	170	65	4	839f62860b4a52d06e6a8fce7632195c7310b89d
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYCN ZFYVE9 RASGRF2 GPR179	1.19e-04	173	65	4	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	Control-Lymphocyte-T_NK-gdT\|Control / Disease, Lineage and Cell Type	RASGRP1 LLGL2 PLEKHF1 RGS9	1.22e-04	174	65	4	202d222a53f967cce172e5f3f1b40920ea13ec6c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASGRP1 RGS9 VWA2 NOS1AP	1.22e-04	174	65	4	e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	ABLIM1 ZFYVE9 PATJ EPB41L3	1.22e-04	174	65	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACSL6 RASGRP1 ABLIM1 PATJ	1.30e-04	177	65	4	64b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	ABLIM1 LLGL2 MICAL2 PATJ	1.36e-04	179	65	4	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABLIM1 LLGL2 PATJ NOS1AP	1.36e-04	179	65	4	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD8_T_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RASGRP1 ABLIM1 PLEKHF1 RNF213	1.36e-04	179	65	4	4e9e0deabf9b09ffcf30fed6d5eae72ce0ef2f1f
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FASN ZFYVE9 PLEKHF1 RGS9	1.39e-04	180	65	4	27672ac6a02172a31851f18decb9acffa8f5a703
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 SGPP2 PATJ NOS1AP	1.39e-04	180	65	4	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	RASGRP1 MICAL2 RNF213 PATJ	1.42e-04	181	65	4	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	E18.5-samps\|World / Age Group, Lineage, Cell class and subclass	FASN SLC44A2 MED1 SLC4A5	1.45e-04	182	65	4	9649f15858d1ede73e068afc59df3ac367b49687
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 SGPP2 PATJ NOS1AP	1.45e-04	182	65	4	1e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM243 SGPP2 PATJ NOS1AP	1.45e-04	182	65	4	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	FASN MICAL2 SGPP2 PATJ	1.51e-04	184	65	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 PATJ EPB41L3 NOS1AP	1.51e-04	184	65	4	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM243 SGPP2 PATJ NOS1AP	1.51e-04	184	65	4	d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP1 ABLIM1 RASGRF2 PATJ	1.51e-04	184	65	4	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 SGPP2 PATJ NOS1AP	1.51e-04	184	65	4	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 PATJ VWA2	1.51e-04	184	65	4	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Rspo3_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABCA12 PABIR3 WDR72	1.53e-04	71	65	3	879551882097cfaa4eccf11cb07f3bae68c777c3
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Rspo3_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ABCA12 PABIR3 WDR72	1.53e-04	71	65	3	8557be86709925cf19125e44c909133fd5adcb62
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMEM243 PATJ SLC4A5 NOS1AP	1.54e-04	185	65	4	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	SGPP2 PATJ SLC4A5 NOS1AP	1.54e-04	185	65	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 SGPP2 PATJ NOS1AP	1.54e-04	185	65	4	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 SGPP2 EPB41L3 NOS1AP	1.54e-04	185	65	4	0c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	LLGL2 RASGRF2 TBCK MED13	1.57e-04	186	65	4	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	ABLIM1 LLGL2 PATJ NOS1AP	1.57e-04	186	65	4	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	LLGL2 RASGRF2 TBCK MED13	1.57e-04	186	65	4	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	mild_COVID-19-CD4+_CTL\|mild_COVID-19 / disease group, cell group and cell class (v2)	RASGRP1 LLGL2 PLEKHF1 RNF213	1.60e-04	187	65	4	49196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCell	LPS-antiTNF-Epithelial_alveolar\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 SGPP2 PATJ NOS1AP	1.60e-04	187	65	4	201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABLIM1 EPB41L3 SLC7A7 WDR72	1.60e-04	187	65	4	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LLGL2 PATJ EPB41L3 NOS1AP	1.60e-04	187	65	4	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MICAL2 SGPP2 PATJ NOS1AP	1.64e-04	188	65	4	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SGPP2 PATJ NOS1AP WDR72	1.64e-04	188	65	4	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP PTPRS SLC44A2 ANKH	1.67e-04	189	65	4	45b9d00a4968fb22207d95228cdcf022afe1e50b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LLGL2 GALNT3 USP43 VWA2	1.67e-04	189	65	4	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SLC18A2 IRAK3 EPB41L3 PPM1J	1.67e-04	189	65	4	2aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP PTPRS SLC44A2 ANKH	1.67e-04	189	65	4	8382d331e01e83591ba9c8ea83edbf2436c18b17
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SGPP2 PATJ EPB41L3 NOS1AP	1.67e-04	189	65	4	5f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	MYCN RASGRF2 MICAL2 EPB41L3	1.67e-04	189	65	4	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
Disease	Amyotrophic lateral sclerosis	SETX SPG11	5.79e-04	17	62	2	cv:C0002736
Disease	Mammary Carcinoma, Human	FASN LLGL2 SPATA18 EPB41L3 L3MBTL3 METTL6	8.16e-04	525	62	6	C4704874
Disease	Mammary Neoplasms, Human	FASN LLGL2 SPATA18 EPB41L3 L3MBTL3 METTL6	8.16e-04	525	62	6	C1257931
Disease	Mammary Neoplasms	FASN LLGL2 SPATA18 EPB41L3 L3MBTL3 METTL6	8.32e-04	527	62	6	C1458155
Disease	Breast Carcinoma	FASN LLGL2 SPATA18 EPB41L3 L3MBTL3 METTL6	9.25e-04	538	62	6	C0678222
Disease	brain cancer (implicated_via_orthology)	LLGL2 L3MBTL3	1.37e-03	26	62	2	DOID:1319 (implicated_via_orthology)
Disease	chronic kidney disease	EPB41L3 PPM1J L3MBTL3 WDR72	1.52e-03	235	62	4	EFO_0003884
Disease	Malignant neoplasm of breast	FASN LLGL2 RASGRF2 SPATA18 EPB41L3 SLC7A7 L3MBTL3 METTL6	1.78e-03	1074	62	8	C0006142

Protein segments in the cluster

Peptide	Gene	Start	Entry
VCFVPKSPPLTVSPR	AGBL5	871	Q8NDL9
LKSPQRFPESPKRFC	ANKRD11	1981	Q6UB99
ICKRPFPPGDRVTFN	ABLIM1	186	O14639
AITRTKFPPTAKPTC	ABCA12	41	Q86UK0
FFIAKPSPVICALRR	GRM3	631	Q14832
SPCPSPVLVRKRAFV	RASGRP1	711	O95267
IRKVPELSSVFLPPC	AP1G2	166	O75843
KFPITTLCCVPTIFR	ACSM5	311	Q6NUN0
LASPVFARLSPKCPA	RGS9	591	O75916
RFSKAQPTCFLLILP	PABIR3	126	Q6P4D5
AVFLSFKSPIPCLPL	L3MBTL3	671	Q96JM7
SLVPYGPFPCKAITR	LLGL2	271	Q6P1M3
TFFDPIVLLPCDLPK	LPCAT4	131	Q643R3
SPCPASKVVRPLRTF	INCENP	481	Q9NQS7
KIPCPKVSRPASTFT	GPR179	2291	Q6PRD1
VNPKISFPPVVDFCL	SPATA18	401	Q8TC71
KSFRCPSPLFLENVP	IRAK3	461	Q9Y616
CVPRVFLQSKFLKPP	METTL6	256	Q8TCB7
PFLAFLRRVKTCNPP	PTPRS	1566	Q13332
VPLPVPRSCLFSESF	CRNKL1	121	Q9BZJ0
QKFKRCPPLPTTSVI	GALNT3	176	Q14435
SVFSKFIPLIPIPER	CNTN1	221	Q12860
LCVVPLRIFSFFPVP	ANKH	366	Q9HCJ1
PFDLFIRKSPTITCL	IGHE	226	P01854
VLIPSKPLARRCFPA	SLC44A2	161	Q8IWA5
AIFPSKPFLQRCFPD	SLC44A5	171	Q8NCS7
VKLECFRFLPPEDTP	NOS1AP	426	O75052
FLCRRPTPQDSPIFL	FASN	1401	P49327
PKVAFRETITAPVPF	GFM1	521	Q96RP9
PIRSPSLVPCFLFIF	EPB41L3	626	Q9Y2J2
ACFFLKFPQPIPVSR	MED1	301	Q15648
KVFPALRSPPCSKIE	MICAL2	1616	O94851
VTSVFRLPFCARKVP	OR10J1	171	P30954
IPFPFLVKRLPFCQS	OR52N5	166	Q8NH56
FLLPRLSPKPVRVCS	PLEKHF1	191	Q96S99
PRSLDIVCKPVPFFL	MRPL15	181	Q9P015
IVCKPVPFFLRGQPI	MRPL15	186	Q9P015
LCRKFSSPPPLAVSR	RASGRF2	721	O14827
RAAPVQPPCRLFFVT	PRDM15	36	P57071
VREPKRIFFGPVSCP	PRAMEF22	446	A3QJZ6
SFPAVVAPFKCSVLP	GARS1	606	P41250
PIKPFLSCFPEVRVY	PPM1J	396	Q5JR12
SCRTTPAIVPPKKFR	SETX	1261	Q7Z333
LLSPECIFPFSVRLK	MTRES1	71	Q9P0P8
QFPCEPFKFLEPTLR	DARS1	331	P14868
CIRLYAPPFILAPVK	MED13	1756	Q9UHV7
TKAPRFVPLTSICFP	PRR12	921	Q9ULL5
LAKLRSINPPCVPFF	SOS1	916	Q07889
SPLFPVCVIVVPFFL	SGPP2	246	Q8IWX5
TPFVTPALRKVCLPF	ATPSCKMT	56	Q6P4H8
PALRKVCLPFVPATT	ATPSCKMT	61	Q6P4H8
KALCPTIFPVVPRLL	ACSL6	356	Q9UKU0
LKTALFPQCTPPSVL	SPG11	1126	Q96JI7
FSFLDIFPKVTCRPP	RNF213	2121	Q63HN8
PPKPLNIFFAVCISL	TMEM243	56	Q9BU79
TFDPFLCVSLPIPLR	USP43	261	Q70EL4
CVDPAVVFPFPVNKR	MYCN	186	P04198
FKFGCTSLRVPPDLL	REV3L	2646	O60673
VSFLKEVPPPFTLVC	PATJ	621	Q8NI35
PRPLKLSVFFPIVFC	SLC7A7	411	Q9UM01
CVFLFSRVPPSLPLQ	VWA2	11	Q5GFL6
TDAKFCPRPFNVLPV	WDR72	656	Q3MJ13
SVFLAPILKCIPLPV	SLC4A5	941	Q9BY07
IRSKPPICTLPNFLF	TBCK	346	Q8TEA7
IIPAKPPVSFFSLRS	TXNDC11	91	Q6PKC3
ILFAPLCFFLRSPPA	SLC18A2	461	Q05940
PCPLFSVRFRKPLFG	ZFYVE9	1086	O95405