Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGTLC2 GGT1

2.01e-046742GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGTLC2 GGT1

2.01e-046742GO:0002951
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGTLC2 GGT1

3.74e-048742GO:0103068
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGTLC2 GGT1

4.80e-049742GO:0036374
GeneOntologyMolecularFunctionprimary miRNA binding

DROSHA DDX5

5.98e-0410742GO:0070878
GeneOntologyCellularComponentlaminin-1 complex

LAMA1 LAMB1

3.90e-053762GO:0005606
GeneOntologyCellularComponenttranscription factor TFIIA complex

GTF2A2 TBP

1.30e-045762GO:0005672
GeneOntologyCellularComponentactin cytoskeleton

SPTBN5 MYO3B MACF1 AKAP13 DIXDC1 SPECC1L DCTN4 ARHGAP21 TNS3

2.37e-04576769GO:0015629
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMB1

5.76e-0410762GO:0043256
GeneOntologyCellularComponentapical cortex

SPTBN5 INSC

5.76e-0410762GO:0045179
DomainCH

SPTBN5 MACF1 DIXDC1 SPECC1L

1.35e-0465754SM00033
DomainCH

SPTBN5 MACF1 DIXDC1 SPECC1L

1.80e-0470754PF00307
Domain-

SPTBN5 MACF1 DIXDC1 SPECC1L

1.90e-04717541.10.418.10
DomainCH

SPTBN5 MACF1 DIXDC1 SPECC1L

2.12e-0473754PS50021
DomainCH-domain

SPTBN5 MACF1 DIXDC1 SPECC1L

2.35e-0475754IPR001715
DomainPDZ

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

2.58e-04141755PF00595
DomainPDZ

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

3.23e-04148755SM00228
DomainGGT_peptidase

GGTLC2 GGT1

3.30e-047752IPR000101
DomainG_GLU_TRANSPEPTIDASE

GGTLC2 GGT1

3.30e-047752PS00462
DomainG_glu_transpept

GGTLC2 GGT1

3.30e-047752PF01019
Domain-

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

3.43e-041507552.30.42.10
DomainPDZ

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

3.54e-04151755PS50106
DomainPDZ

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

3.65e-04152755IPR001478
DomainLAM_G_DOMAIN

SLIT2 FAT3 LAMA1

4.74e-0438753PS50025
DomainLaminin_G_2

SLIT2 FAT3 LAMA1

5.52e-0440753PF02210
DomainLamG

SLIT2 FAT3 LAMA1

7.32e-0444753SM00282
DomainLaminin_G_1

SLIT2 LAMA1

8.55e-0411752PF00054
DomainLaminin_G

SLIT2 FAT3 LAMA1

1.64e-0358753IPR001791
DomainLaminin_N

LAMA1 LAMB1

1.84e-0316752IPR008211
DomainLAMININ_NTER

LAMA1 LAMB1

1.84e-0316752PS51117
DomainLaminin_N

LAMA1 LAMB1

1.84e-0316752PF00055
DomainLamNT

LAMA1 LAMB1

1.84e-0316752SM00136
DomainEGF

SLIT2 FAT3 TLL1 LAMA1 LAMB1

2.55e-03235755SM00181
DomainEGF-like_dom

SLIT2 FAT3 TLL1 LAMA1 LAMB1

3.27e-03249755IPR000742
Domain4_helix_cytokine-like_core

ZNF263 CSF1 KITLG

3.29e-0374753IPR009079
DomainEGF_1

SLIT2 FAT3 TLL1 LAMA1 LAMB1

3.62e-03255755PS00022
DomainActinin_actin-bd_CS

SPTBN5 MACF1

3.81e-0323752IPR001589
DomainSpectrin

SPTBN5 MACF1

3.81e-0323752PF00435
DomainACTININ_2

SPTBN5 MACF1

3.81e-0323752PS00020
DomainACTININ_1

SPTBN5 MACF1

3.81e-0323752PS00019
DomainEGF-like_CS

SLIT2 FAT3 TLL1 LAMA1 LAMB1

4.00e-03261755IPR013032
Pubmed

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.

HDAC5 DROSHA DDX5

3.49e-07776326965827
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SFXN1 SLIT2 TRAP1 MACF1 HELZ AKAP13 POGZ UPF1 SPECC1L PRPF8 TNS3

4.95e-07724761136232890
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SFXN1 CA12 UBQLNL MCMBP DROSHA PPFIA2 MYO3B LAMA1 AKAP13 PRPF8 DDX5

5.81e-07736761129676528
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

TRAP1 VPS13D OTUB1 SGO2 UPF1 PRPF8 TRRAP

8.65e-0723576730258100
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

AFDN RGS3 ARHGAP21 TJP3

1.05e-063576433864728
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

SLIT2 TOM1 LAMB1 MACF1 HELZ UPF1 STIL PRPF8

1.20e-0635876832460013
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FSIP2 VPS13D MCMBP PHACTR2 MACF1 HELZ AFDN AKAP13 STIL ARHGAP21 TNS3

2.66e-06861761136931259
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTBN5 KRT1 TRAP1 HELZ TRRAP PLXNA1

3.57e-0618776626460568
Pubmed

Expression of a novel recombinant stem cell factor/macrophage colony-stimulating factor fusion protein in baculovirus-infected insect cells.

CSF1 KITLG

4.71e-06276215866728
Pubmed

Monoclonal anti-mouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain.

LAMA1 LAMB1

4.71e-06276216631359
Pubmed

Form and function: the laminin family of heterotrimers.

LAMA1 LAMB1

4.71e-06276210842354
Pubmed

Laminin terminates the Netrin/DCC mediated attraction of vagal sensory axons.

LAMA1 LAMB1

4.71e-06276218418846
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

LAMA1 LAMB1 HELZ AFDN UPF1 TBP

5.71e-0620376622083510
Pubmed

Tagging genes with cassette-exchange sites.

DROSHA OTUB1 MACF1 HELZ AFDN AKAP13 PLXNA1

8.94e-0633576715741177
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SLIT2 FAT3 LAMA1 MACF1 PRPF8 DDX5

1.28e-0523476636243803
Pubmed

Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.

LAMA1 LAMB1

1.41e-0537622100263
Pubmed

Signaling by p38 MAPK stimulates nuclear localization of the microprocessor component p68 for processing of selected primary microRNAs.

DROSHA DDX5

1.41e-05376223482664
Pubmed

Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding.

GTF2A2 TBP

1.41e-0537628626665
Pubmed

Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.

LAMA1 LAMB1

1.41e-0537627669546
Pubmed

Three-dimensional analysis of the developing pituitary gland in the mouse.

LAMA1 LAMB1

1.41e-0537629603432
Pubmed

Differential expression of laminin A and B chains during development of embryonic mouse organs.

LAMA1 LAMB1

1.41e-0537622088723
Pubmed

Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.

LAMA1 LAMB1

1.41e-0537621907584
Pubmed

Increased blood myeloid dendritic cells and dendritic cell-poietins in Langerhans cell histiocytosis.

CSF1 KITLG

1.41e-05376215728521
Pubmed

Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.

LAMA1 LAMB1

1.41e-0537621292752
Pubmed

Human lung expresses unique gamma-glutamyl transpeptidase transcripts.

GGTLC2 GGT1

1.41e-0537627689219
Pubmed

Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress.

DROSHA DDX5

1.41e-05376224219989
Pubmed

An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.

LAMA1 LAMB1

1.41e-05376212615822
Pubmed

New neurons follow the flow of cerebrospinal fluid in the adult brain.

SLIT2 IFT88

1.41e-05376216410488
Pubmed

High proliferation and delamination during skin epidermal stratification.

KRT1 IFT88 LAMA1

1.50e-052276334050161
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

HDAC5 DROSHA SNX17 TOM1 POGZ UPF1 ARHGAP21 STAT2 TNS3 DDX5 TJP3

1.55e-051038761126673895
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SFXN1 KRT1 DROSHA BTBD17 MACF1 POGZ UPF1 PRPF8 TRRAP CSTF2T DDX5

2.26e-051082761138697112
Pubmed

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.

LAMA1 LAMB1

2.82e-05476212820173
Pubmed

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

GTF2A2 TBP

2.82e-0547627958900
Pubmed

Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.

LAMA1 LAMB1

2.82e-0547629299121
Pubmed

Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation.

LAMA1 LAMB1

2.82e-0547629885251
Pubmed

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

GTF2A2 TBP

2.82e-0547628224850
Pubmed

Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.

LAMA1 LAMB1

2.82e-0547629201115
Pubmed

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

GTF2A2 TBP

2.82e-0547627724559
Pubmed

Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding.

GTF2A2 TBP

2.82e-0547629603936
Pubmed

Depletion of nuclear actin is a key mediator of quiescence in epithelial cells.

LAMA1 LAMB1

2.82e-05476221172822
Pubmed

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8.

DROSHA DDX5

2.82e-05476222222205
Pubmed

Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development.

CSF1 KITLG

2.82e-0547621374350
Pubmed

Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML.

CSF1 KITLG

2.82e-05476214654075
Pubmed

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

LAMA1 LAMB1

2.82e-0547622099832
Pubmed

Role of mesenchymal nidogen for epithelial morphogenesis in vitro.

LAMA1 LAMB1

2.82e-0547627925005
Pubmed

Role of laminin terminal globular domains in basement membrane assembly.

LAMA1 LAMB1

2.82e-05476217517882
Pubmed

Laminin-1 reexpression in Alport mouse glomerular basement membranes.

LAMA1 LAMB1

2.82e-05476212631063
Pubmed

New pUC-derived expression vectors for rapid construction of cDNA libraries.

LAMA1 LAMB1

2.82e-0547622436975
Pubmed

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.

LAMA1 LAMB1

2.82e-05476219074617
Pubmed

Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling.

DROSHA DDX5

2.82e-05476225963660
Pubmed

Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells.

KITLG ANGPTL3

2.82e-05476220385801
Pubmed

Modulation of microRNA processing by p53.

DROSHA DDX5

2.82e-05476219626115
Pubmed

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.

LAMA1 LAMB1

2.82e-0547628034675
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

KRT1 ASXL1 TRAP1 TOM1 HELZ UPF1 PRPF8 ARHGAP21 CSTF2T DDX5

3.21e-05922761027609421
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SFXN1 SNX17 MACF1 AFDN AKAP13 POGZ UPF1 DCTN4 PRPF8 TRRAP TNS3 DDX5

3.55e-051353761229467282
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

SLIT2 TOM1 ANGPTL3 SPECC1L ECE2

3.67e-0517076523314748
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

KRT1 TRAP1 SGTA OTUB1 TOM1 MACF1 AFDN UPF1 DCTN4 PRPF8 DDX5

3.92e-051149761135446349
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SFXN1 MCMBP MRC2 SGTA OTUB1 TOM1 BCCIP AFDN UPF1 PRPF8 TNS3 DDX5

3.92e-051367761232687490
Pubmed

Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10.

CD84 KITLG STAT2

4.31e-053176315921521
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KRT1 MCMBP HDAC5 DROSHA MACF1 HELZ STAT2 DDX5

4.37e-0558876838580884
Pubmed

Functional proteomics mapping of a human signaling pathway.

DROSHA SNX17 OTUB1 TOM1 BCCIP MACF1 AFDN RGS3

4.53e-0559176815231748
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGTLC2 GGT1

4.69e-05576218063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGTLC2 GGT1

4.69e-05576210940879
Pubmed

Expression of laminin and nidogen genes during the postimplantation development of the mouse placenta.

LAMA1 LAMB1

4.69e-0557628286607
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-05576211095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGTLC2 GGT1

4.69e-0557627641802
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGTLC2 GGT1

4.69e-05576223615310
Pubmed

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

LAMA1 LAMB1

4.69e-05576219416897
Pubmed

The mouse skin carcinogenesis model.

GGTLC2 GGT1

4.69e-0557629627710
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGTLC2 GGT1

4.69e-05576212453183
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGTLC2 GGT1

4.69e-05576211003618
Pubmed

Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.

LAMA1 LAMB1

4.69e-05576210964500
Pubmed

Hematopoietic cytokines as tumor markers.

CSF1 KITLG

4.69e-05576215576295
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGTLC2 GGT1

4.69e-05576210392451
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGTLC2 GGT1

4.69e-0557622891746
Pubmed

Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.

LAMA1 LAMB1

4.69e-0557629719032
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGTLC2 GGT1

4.69e-05576219850887
Pubmed

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.

LAMA1 LAMB1

4.69e-0557627544312
Pubmed

Laminin-10 is crucial for hair morphogenesis.

LAMA1 LAMB1

4.69e-05576212743034
Pubmed

Localization of the 110 kDa receptor for laminin in brains of embryonic and postnatal mice.

LAMA1 LAMB1

4.69e-0557627895274
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-05576212810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-0557628755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-05576211089562
Pubmed

Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.

LAMA1 LAMB1

4.69e-0557628719886
Pubmed

The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development.

LAMA1 LAMB1

4.69e-0557621725162
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGTLC2 GGT1

4.69e-05576228660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-05576212468440
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGTLC2 GGT1

4.69e-05576226977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGTLC2 GGT1

4.69e-05576212225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGTLC2 GGT1

4.69e-0557627775425
Pubmed

Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo.

LAMA1 LAMB1

4.69e-0557628359228
Pubmed

The germ cell-specific transcription factor ALF. Structural properties and stabilization of the TATA-binding protein (TBP)-DNA complex.

GTF2A2 TBP

4.69e-05576212107178
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGTLC2 GGT1

4.69e-0557628566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGTLC2 GGT1

4.69e-05576230591459
Pubmed

Expression of collagen alpha 1(IV), laminin and nidogen genes in the embryonic mouse lung: implications for branching morphogenesis.

LAMA1 LAMB1

4.69e-0557627516699
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGTLC2 GGT1

4.69e-0557629139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGTLC2 GGT1

4.69e-05576220622017
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGTLC2 GGT1

4.69e-0557629546365
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGTLC2 GGT1

4.69e-05576211795900
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGTLC2 GGT1

4.69e-0557627485380
InteractionYAP1 interactions

SFXN1 KRT1 TRAP1 MCMBP DROSHA MYO3B OTUB1 TOM1 AFDN POGZ UPF1 PRPF8 TRRAP CSTF2T DDX5

1.02e-0510957515int:YAP1
InteractionPDIA3 interactions

FSIP2 TRAP1 KITLG SGTA OTUB1 BCCIP LAMB1 PRPF8 TRRAP PLXNA1

1.03e-054767510int:PDIA3
GeneFamilyPDZ domain containing

FRMPD2 AFDN RGS3 ARHGAP21 TJP3

9.75e-051525551220
GeneFamilyUPF1 like RNA helicases

HELZ UPF1

4.91e-04115521169
GeneFamilyLaminin subunits

LAMA1 LAMB1

5.88e-0412552626
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGTLC2 GGT1

6.94e-0413552564
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

GTF2A2 TBP

2.61e-0325552565
CoexpressionNAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_DN

CD84 SPTBN5 CSF1 OTUB1 MACF1 AKAP13 GGTLC2 PLXNA1

8.00e-07260758M41075
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

3.66e-081907671196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

3.94e-0819276725492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

3.94e-08192767de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

SLIT2 PHACTR2 FAT3 LAMB1 MACF1 RGS3 TNS3

3.94e-0819276762904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-081957671c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-081957673a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellPND10-Mesenchymal-Mesenchymal_structural|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-0819576711d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-081957672b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-081957671f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1 SPECC1L TNS3

4.38e-0819576710f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

SLIT2 KITLG MRC2 MACF1 SPECC1L TNS3

6.54e-07180766adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SLIT2 MRC2 LAMB1 MACF1 SPECC1L TNS3

8.69e-07189766dc5164591dea45b420798b94dda211be03daa70c
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SLIT2 CSF1 INSC PPFIA2 FAT3 RGS3

8.69e-0718976646c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLIT2 MRC2 FAT3 MACF1 SPECC1L TNS3

9.24e-07191766a05e9a7eb137d804570dd7d8905975d735738767
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

SLIT2 CSF1 KITLG FAT3 RGS3 TNS3

9.24e-0719176678ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLIT2 MRC2 FAT3 MACF1 SPECC1L TNS3

9.53e-071927660afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SPTBN5 SLC26A3 LRRC43 SYCE1L

9.69e-0744764405ac4aeee539322cfe661c7531248f81271be8d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SPTBN5 SLC26A3 LRRC43 SYCE1L

9.69e-0744764a2c99e8ca635590a1f167b68bc390e2aa01e26be
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 MACF1 SPECC1L TNS3

9.82e-071937668d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 MACF1 SPECC1L TNS3

9.82e-071937661b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SLIT2 MRC2 INSC PPFIA2 FAT3 RGS3

9.82e-07193766035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CA12 SLIT2 MRC2 LAMB1 MACF1 SPECC1L

1.14e-061987660c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLIT2 MRC2 FAT3 LAMB1 MACF1 RGS3

1.17e-061997667f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLIT2 MRC2 FAT3 LAMB1 MACF1 RGS3

1.17e-06199766301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLIT2 MRC2 FAT3 LAMB1 MACF1 RGS3

1.17e-061997669a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMA1 LAMB1 MACF1 SPECC1L

1.17e-06199766a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLIT2 ABCC3 MRC2 FAT3 MACF1 AFDN

1.17e-061997666bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMA1 LAMB1 MACF1 SPECC1L

1.21e-062007669b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 KITLG TRHR PPFIA2 LAMB1

5.33e-061477652885978bcfc5623967c0c1204dadf5c78c74a082
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

SLIT2 MRC2 ANGPTL3 SGO2 TNS3

5.69e-06149765651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 FAT3 TLL1 RXFP2 LAMA1

8.05e-06160765c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 FAT3 TLL1 RXFP2 LAMA1

8.05e-0616076525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLIT2 FAT3 MACF1 SPECC1L TNS3

8.30e-06161765b19f82dd98a3064581793711bb70373f18abecd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 TRHR LAMA1 LAMB1 GGTLC2

9.07e-061647651cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 SLIT2 PHACTR2 KITLG TJP3

1.05e-051697650332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SPTBN5 CSF1 IFT88 SPECC1L TJP3

1.11e-051717653d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FAT3 LAMB1 MACF1 SPECC1L TNS3

1.21e-051747653c47d069bd836599a8d40eae485c23d4d3487517
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 MACF1 SPECC1L TNS3

1.28e-05176765cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 DIXDC1 SPECC1L PLXNA1 STAT2

1.35e-05178765c87945146b2734141f07b39d268e0d8086ee0364
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

SLIT2 CSF1 KITLG MRC2 TNS3

1.62e-05185765b8cd94cf18308b514fc61557550225794ffd2860
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 PHACTR2 KITLG MYO3B LAMB1

1.67e-05186765d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

CSF1 KITLG LAMB1 RGS3 TNS3

1.67e-051867656ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

1.75e-05188765de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellMesenchymal_cells-Osteoblasts|World / Lineage and Cell class

SLIT2 INSC PPFIA2 FAT3 RGS3

1.75e-0518876589f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 PHACTR2 KITLG MYO3B LAMB1

1.80e-0518976590aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

SLIT2 ABCC3 FAT3 MACF1 AFDN

1.85e-0519076562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 FAT3 LAMA1 LAMB1 TNS3

1.89e-05191765d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

SLIT2 MRC2 MACF1 SPECC1L TNS3

1.89e-051917653379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC2 LAMB1 MACF1 SPECC1L TNS3

1.89e-051917650b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

SLIT2 CSF1 MRC2 INSC RGS3

1.94e-051927650703b8ec6960ff975ee5a2737054db67cab016b5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 KITLG MYOC LAMB1 SYCE1L

1.99e-051937657cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1

1.99e-051937654c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 FAT3 LAMB1 MACF1

1.99e-05193765ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 KITLG FAT3 LAMB1 MACF1

1.99e-0519376599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 KITLG MYO3B AFDN TJP3

2.04e-0519476504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SLIT2 LAMB1 MACF1 SPECC1L TNS3

2.04e-051947654f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 MACF1 SPECC1L TNS3

2.09e-05195765b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 LAMB1 MACF1 SPECC1L TNS3

2.09e-051957656bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.09e-05195765df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.09e-051957654243190ad291d56694e2155954dbaa879c9d3844
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 LAMB1 MACF1 SPECC1L TNS3

2.09e-05195765a3b468125e48f072255cede7645f6692298ecf54
ToppCellPND07-Mesenchymal-Mesenchymal_structural|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 MACF1 SPECC1L TNS3

2.09e-051957652f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 FAT3 LAMB1 MACF1 AFDN

2.14e-051967656730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 FAT3 LAMB1 MACF1 AFDN

2.14e-0519676521dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.14e-051967659737a5f006d37b549f281e1863aca558e1e4dc99
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 MACF1 SPECC1L TNS3

2.14e-05196765617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.14e-0519676542e9828222a9663525d571633e8a454c30bfa7f8
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CA12 ABCC3 CSF1 MRC2 PLXNA1

2.14e-05196765b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 MRC2 MACF1 SPECC1L TNS3

2.14e-05196765db64ab27374f82553ee577aec056141170f3656f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.14e-05196765cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 LAMB1 MACF1 SPECC1L TNS3

2.20e-0519776506a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.20e-051977656c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.20e-0519776563b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLIT2 ABCC3 FAT3 MACF1 AFDN

2.20e-051977650034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.20e-05197765fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.20e-0519776513896ec65ccda0b928c91d41112dc01b480036b7
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLIT2 LAMB1 MACF1 SPECC1L TNS3

2.20e-05197765d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.25e-051987650a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 INSC PPFIA2 FAT3 RGS3

2.25e-051987651f956e369e00d37835095a001db4b62a79014532
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 INSC PPFIA2 FAT3 RGS3

2.25e-05198765dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.25e-051987659d61483b0decac2fe90045b3474843360b2c49b3
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PHACTR2 FAT3 LAMB1 MACF1 RGS3

2.25e-05198765e0e47cf65774191981840b22905b2094b95abe0f
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.25e-051987656a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CA12 SLIT2 CSF1 FAT3 RGS3

2.25e-0519876555d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 KITLG MYOC LAMB1 SYCE1L

2.25e-0519876512cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CA12 SLIT2 CSF1 FAT3 RGS3

2.25e-051987658602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.25e-05198765f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.30e-051997657b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.30e-05199765c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 MRC2 INSC FAT3 RGS3

2.30e-05199765f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.30e-0519976530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.30e-05199765e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLIT2 MRC2 FAT3 LAMB1 MACF1

2.30e-0519976566a79732caf2f04c09b4d9832377aa01ca477677
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLIT2 MYOC MRC2 LAMB1 MACF1

2.36e-052007658978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.36e-0520076564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.36e-05200765b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellwk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SLIT2 ABCC3 MRC2 FAT3 MACF1

2.36e-052007650ed49c2177b58269ff7653db6be7d68633a5d34a
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLIT2 MRC2 LAMB1 MACF1 SPECC1L

2.36e-0520076550ca6550998e461ef26dd670351060bd940765a8
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SLIT2 KITLG FAT3 LAMB1 MACF1

2.36e-05200765aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MACF1 HELZ AKAP13 STAT2 DDX5

2.36e-0520076512f1685ce8f218433068e090c9d839cd5a1910bf
DrugSulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A

CA12 MCMBP CSF1 HDAC5 AKAP13 POGZ PLXNA1

3.94e-061977571810_DN
DrugAtracurium besylate [64228-81-5]; Down 200; 3.2uM; PC3; HT_HG-U133A

CA12 VPS13D CSF1 AKAP13 UPF1 PLXNA1 CSTF2T

4.07e-061987571824_DN
DrugKhellin [82-02-0]; Up 200; 15.4uM; HL60; HG-U133A

CD84 CA12 PHACTR2 MRC2 AKAP13 CSTF2T ECE2

4.21e-061997572004_UP
DrugProbucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

ABCC3 VPS13D CSF1 PPFIA2 AFDN RGS3 STAT2

4.35e-062007575626_UP
Drugphenyl azide

KRT1 DROSHA TBP

2.70e-0518753CID000069319
DrugSizofiran

CSF1 KITLG

3.21e-053752ctd:D012566
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

ASXL1 VPS13D MACF1 RNF41 TRRAP CSTF2T

4.01e-051917564168_DN
DrugAtovaquone [95233-18-4]; Up 200; 11uM; HL60; HT_HG-U133A

CA12 SLIT2 ABCC3 CSF1 AFDN RGS3

4.50e-051957562480_UP
DrugISO-1 cpd

KITLG HDAC5 LAMA1 PLIN1

4.60e-0560754CID006098948
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

CA12 ABCC3 VPS13D CSF1 OTUB1 CSTF2T

4.63e-051967563971_DN
Drugarachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A

VPS13D MRC2 SGTA POGZ RGS3 PLXNA1

4.63e-05196756443_DN
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; HL60; HT_HG-U133A

VPS13D MCMBP PHACTR2 SGTA MACF1 CSTF2T

4.63e-051967561843_DN
DrugChloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A

SGTA TOM1 AKAP13 SPECC1L RGS3 PLXNA1

4.77e-051977561795_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A

SFXN1 VPS13D UPF1 SPECC1L DCTN4 RGS3

4.90e-051987566929_DN
DrugMephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A

ABCC3 VPS13D CSF1 LAMB1 RNF41 PLXNA1

4.90e-051987566275_UP
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

ZNF263 SGTA AKAP13 POGZ RGS3 TJP3

4.90e-051987565475_DN
DrugNSC19989

GTF2A2 TBP

6.40e-054752CID006474067
DiseaseLissencephaly

LAMB1 MACF1

9.00e-056732C0266463
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGTLC2 GGT1

1.26e-047732DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGTLC2 GGT1

1.67e-048732DOID:0050741 (biomarker_via_orthology)
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ASXL1 PRPF8

6.21e-0415732DOID:0050908 (implicated_via_orthology)
Diseaselupus nephritis (is_marker_for)

CSF1 OTUB1

8.02e-0417732DOID:0080162 (is_marker_for)
Diseasegamma-glutamyltyrosine measurement

ARHGAP21 GGT1

2.04e-0327732EFO_0021144
DiseaseBilateral Wilms Tumor

ASXL1 DROSHA

2.35e-0329732C2930471

Protein segments in the cluster

PeptideGeneStartEntry
QRPQETVIRELQPQQ

AFDN

1471

P55196
NNTLRTPNIDQLAEE

ARSD

61

P51689
NPEEQLIIIQSRLDQ

DIXDC1

331

Q155Q3
ELLSNQSEAVLQEPQ

BTBD17

96

A6NE02
NTQDILIPNVLLSQE

AKAP13

1111

Q12802
PTRVQEDQQRTININ

C14orf28

161

Q4W4Y0
PTDVESTLLQLQEQN

SPECC1L

236

Q69YQ0
LEEQLTNLIQNQPET

ANGPTL3

141

Q9Y5C1
QQQLLFLLPEVDRQV

ASXL1

281

Q8IXJ9
QQLDTVLQLNERPVE

RGS3

336

P49796
RIQQFLSQEELDPQS

ABCC3

601

O15438
VRQTLNPTQEQIEEL

MOGAT1

291

Q96PD6
PVNTAELTDLLIQQN

BCCIP

86

Q9P287
LVLAPTRELAQQVQQ

DDX5

171

P17844
PQADNIIRNVLNIIT

FSIP2

5086

Q5CZC0
NPVQISQEQLLALET

CA12

241

O43570
LEIQLANITVPQDQR

ECE2

351

P0DPD6
LQQVSELINRTEPSI

ECE2

416

P0DPD6
IIININRAQLTNPEV

PLXNA1

1026

Q9UIW2
TINQSLLQPLNVEID

KRT1

156

P04264
QLTLDQAARPQETQE

MYOC

101

Q99972
PIRLEQDQTTAQLQV

MACF1

1826

O94854
TTLIQRDQEPIPQNI

MACF1

3026

O94854
QQEAQLVTITNPLEQ

MRC2

1006

Q9UBG0
TPQQLQNLTEDIRER

LAMB1

1536

P07942
QLTEQLRSLIPNEDV

LRRC37B

801

Q96QE4
QLLPNVTTVERNIDQ

GGTLC2

156

Q14390
LSQRPTTEELEQRNI

PHACTR2

521

O75167
DTQVELQFQLNRLPL

HELZ

586

P42694
EQENVLQRVLQLPVV

PLIN1

16

O60240
RIQQEIAVQNPLVSE

OTUB1

36

Q96FW1
PSEQEQLRARQITAQ

UPF1

246

Q92900
QREQVTTPENINLDL

IFT88

181

Q13099
DNTPNAIAIVQLQEL

CSF1

101

P09603
IQNSPDNIELIISQS

FRMPD2

846

Q68DX3
IIILEQPLDREQQSS

FAT3

3186

Q8TDW7
LQDSDFQQLVQPRLV

INSC

551

Q1MX18
PEQRQSILILKEQIQ

CSTF2T

596

Q9H0L4
SVDPTLREQQLQQEL

HDAC5

66

Q9UQL6
EVTTLQQRLLQPDFQ

DCTN4

241

Q9UJW0
RSVNPNLQNLEETIE

RNF41

181

Q9H4P4
EPLTVEVQIQLNQCR

LRRC43

631

Q8N309
IPTQNTQARQILERE

PPFIA2

1156

O75334
QQELDLNSPRNTTLE

MCMBP

111

Q9BTE3
QNPLQFVTNELRIID

PCDHB3

111

Q9Y5E6
LQLQEPNTDRQLIET

DROSHA

1086

Q9NRR4
QESLDELIQSQQITP

GTF2A2

16

P52657
IVVSNRQVDELQQPL

STAT2

696

P52630
VTDPRNILLTNEQLE

SFXN1

31

Q9H9B4
VSELNQTQLQPRAVV

TRHR

6

P34981
QQNPELIEQLRSQIR

SGTA

286

O43765
NIFQIDRTIDLTQNP

TLL1

71

O43897
NRRIITVQLDENNPV

LAMA1

2591

P25391
LTQREQQLPVNEETL

POGZ

1036

Q7Z3K3
QSLDLERIEIPNINT

RXFP2

356

Q8WXD0
ELQIPALSTRDNENQ

SGO2

666

Q562F6
NVLQIFQTPEDQELT

CD84

176

Q9UIB8
QPSLTRAVENIQINE

KITLG

241

P21583
NQIEVLDQPINTTDL

SLC26A3

611

P40879
PQIEDLISRINDLQQ

SYCE1L

46

A8MT33
PTLDIDQSIEQLNRL

TNS3

691

Q68CZ2
TVLLQRVQPQADTLE

SPTBN5

916

Q9NRC6
ISAPSQQRQQIAEIE

PRPF8

2016

Q6P2Q9
FLRRAQQETQQVPTE

SNX17

101

Q15036
DTPVLRNITNEVLQT

STIL

1191

Q15468
QPIQNTNSLSILEEQ

TBP

41

P20226
QRVLELIPQIANEQL

TOM1

266

O60784
SQELEQSPQSLIVQE

TRAV34

21

A0A0B4J273
TNLPETITEIRLEQN

SLIT2

296

O94813
QQNPEVSRLLLDNSE

UBQLNL

206

Q8IYU4
ILQVNDVPFQNLTRE

TJP3

426

O95049
QEERAQLLQPTLEIN

TRAP1

631

Q12931
ELPVSQRNQDLSLQE

ARHGAP21

706

Q5T5U3
TPLLQAAQQIIELQE

TRRAP

2931

Q9Y4A5
QVNNLDIILNPETIV

VPS13D

1106

Q5THJ4
LEQFLTILPQEIQSR

ZNF263

86

O14978
TILPQEIQSRVQELH

ZNF263

91

O14978
NQLLPNVTTVERNID

GGT1

506

P19440
VLAENSISPELQQQI

LRRC73

236

Q5JTD7
VNRINTLLQPDENIC

MYO3B

696

Q8WXR4