Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	ZSWIM8 SPOPL KLHL7	7.04e-05	39	43	3	GO:0031463
Domain	ZINC_FINGER_C2H2_2	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 GPATCH8 REPIN1 ZNF316	2.00e-04	775	40	8	PS50157
Domain	ZINC_FINGER_C2H2_1	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 GPATCH8 REPIN1 ZNF316	2.04e-04	777	40	8	PS00028
Domain	Znf_C2H2-like	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 GPATCH8 REPIN1 ZNF316	2.40e-04	796	40	8	IPR015880
Domain	Znf_C2H2	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 GPATCH8 REPIN1 ZNF316	2.59e-04	805	40	8	IPR007087
Domain	ZnF_C2H2	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 GPATCH8 REPIN1 ZNF316	2.66e-04	808	40	8	SM00355
Domain	-	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 REPIN1 ZNF316	5.33e-04	679	40	7	3.30.160.60
Domain	zf-C2H2	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 REPIN1 ZNF316	6.02e-04	693	40	7	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	HIVEP3 ZFHX2 PRDM13 ZBTB45 ZNF497 REPIN1 ZNF316	6.07e-04	694	40	7	IPR013087
Domain	BTB	ZBTB45 SPOPL KLHL7	2.76e-03	131	40	3	PF00651
Domain	BTB	ZBTB45 SPOPL KLHL7	4.83e-03	160	40	3	PS50097
Domain	BTB	ZBTB45 SPOPL KLHL7	6.69e-03	180	40	3	SM00225
Domain	BTB/POZ_dom	ZBTB45 SPOPL KLHL7	7.22e-03	185	40	3	IPR000210
Domain	Homeobox_CS	ZFHX2 SIX4 BARX1	7.33e-03	186	40	3	IPR017970
Domain	SKP1/BTB/POZ	ZBTB45 SPOPL KLHL7	7.65e-03	189	40	3	IPR011333
Domain	RNaseH-like_dom	PRPF8 POLE	9.58e-03	69	40	2	IPR012337
Domain	Homeobox	ZFHX2 SIX4 BARX1	1.36e-02	234	40	3	PF00046
Domain	HOMEOBOX_1	ZFHX2 SIX4 BARX1	1.40e-02	236	40	3	PS00027
Domain	HOX	ZFHX2 SIX4 BARX1	1.41e-02	237	40	3	SM00389
Domain	Homeobox_dom	ZFHX2 SIX4 BARX1	1.44e-02	239	40	3	IPR001356
Domain	HOMEOBOX_2	ZFHX2 SIX4 BARX1	1.44e-02	239	40	3	PS50071
Pubmed	Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus.	MST1R HYAL2	1.49e-06	2	43	2	12676986
Pubmed	Tagging genes with cassette-exchange sites.	ARHGEF12 GPATCH8 FHIT RSBN1L DOCK9 DMXL1	3.45e-06	335	43	6	15741177
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	ARHGEF12 MST1R ORC3 IL5RA LARGE1	4.16e-05	313	43	5	20800603
Pubmed	Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.	SIX4 DOCK9	9.78e-05	12	43	2	22987639
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	COL18A1 GPATCH8 SPOPL REPIN1 RSBN1L DMXL1 AMDHD2 ZNF316	1.06e-04	1215	43	8	15146197
Pubmed	A panel of sputum-based genomic marker for early detection of lung cancer.	FHIT HYAL2	1.15e-04	13	43	2	20864512
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGEF12 GPATCH8 DOCK9 DENND4B LARGE1	1.43e-04	407	43	5	12693553
Pubmed	DNA replication in eukaryotic cells.	ORC3 POLE	2.26e-04	18	43	2	12045100
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP3 MST1R REPIN1 PLA2G4B POLE DOCK9 ZNF316	3.80e-04	1105	43	7	35748872
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	PRPF8 REPIN1 DMXL1 AMDHD2	4.13e-04	283	43	4	18854154
Pubmed	Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals.	SIX4 BARX1	7.23e-04	32	43	2	38110169
Pubmed	A genome-wide association study (GWAS) for bronchopulmonary dysplasia.	HIVEP3 FHIT	8.17e-04	34	43	2	23897914
Pubmed	The sequence of the human genome.	PRDM13 ABAT WDFY4 PLA2G4B DENND4B	8.61e-04	603	43	5	11181995
Cytoband	3p21.3	MST1R HYAL2	1.42e-03	59	43	2	3p21.3
Cytoband	19q13.43	ZBTB45 ZNF497	3.05e-03	87	43	2	19q13.43
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP3 ZFHX2 ZBTB45 ZNF497 REPIN1 ZNF316	1.21e-03	718	31	6	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB45 SPOPL KLHL7	1.54e-03	134	31	3	861
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MOXD1 CBLN3 WDFY4 LARGE1	1.54e-05	156	43	4	d81e78bec5c8a3f3ec9e1447ebab2c5805b815eb
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABAT FHIT WDFY4 LARGE1	2.53e-05	177	43	4	3535575686c9700ab72700aae6f2070ebbb50044
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZBTB45 EOGT WDFY4 ZNF316	2.89e-05	183	43	4	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	WDFY4 REPIN1 PLA2G4B HYAL2	3.01e-05	185	43	4	0e8064bb317f26959d3c59b4f73d0c455161ccd7
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZBTB45 EOGT WDFY4 ZNF316	3.08e-05	186	43	4	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIVEP3 COL18A1 MOXD1 EOGT	3.41e-05	191	43	4	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	3.85e-05	197	43	4	9244f087ba4b60fdc81d54ce91860de715b3e12c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	3.93e-05	198	43	4	218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	3.93e-05	198	43	4	72e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	3.93e-05	198	43	4	7cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	3.93e-05	198	43	4	e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	4.00e-05	199	43	4	9c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL18A1 EOGT HYAL2 DOCK9	4.00e-05	199	43	4	72b34bce8157abe389e95cd3ed8ba578dce0cbf6
Disease	bronchopulmonary dysplasia	HIVEP3 ABAT FHIT	3.39e-05	45	41	3	MONDO_0019091
Disease	prostate cancer (implicated_via_orthology)	PRPF8 POLE	9.68e-04	33	41	2	DOID:10283 (implicated_via_orthology)
Disease	lean body mass	MST1R MOXD1 FHIT RSBN1L	1.86e-03	379	41	4	EFO_0004995
Disease	hepatocellular carcinoma (implicated_via_orthology)	COL18A1 FHIT	2.13e-03	49	41	2	DOID:684 (implicated_via_orthology)
Disease	memory performance	ARHGEF12 HIVEP3 PRPF8 RSBN1L	2.46e-03	409	41	4	EFO_0004874
Disease	chemokine (C-C motif) ligand 27 measurement	FHIT LARGE1	4.29e-03	70	41	2	EFO_0008082
Disease	Retinitis pigmentosa	PRPF8 KLHL7	4.78e-03	74	41	2	cv:C0035334
Disease	Amphetamine Abuse	FHIT LARGE1	4.90e-03	75	41	2	C0236807
Disease	Amphetamine Addiction	FHIT LARGE1	4.90e-03	75	41	2	C0236804

Protein segments in the cluster

Peptide	Gene	Start	Entry
HIPFFLHNNRHIATV	EOGT	46	Q5NDL2
AAAVPPAAAANHHHH	BTBD11	321	A6QL63
HHVHRNTPLHANALC	DMXL1	341	Q9Y485
HRFHLNDLACHSVLP	DMXL1	636	Q9Y485
RPAHLAVFLHHVVSQ	ARHGEF12	381	Q9NZN5
GASIALFTARLHHPH	PTPN9	106	P43378
LRVARTHHANHALPV	HYAL2	276	Q12891
LFHRRNPLHFHLIAD	LARGE1	161	O95461
ELHAHAPHFQVSLLR	MUC20	691	Q8N307
PTLVFRDHHAHLFLN	ABAT	476	P80404
VQALLAARPFHSHLA	BARX1	61	Q9HBU1
QHAILQHHAAAAAAA	GPATCH8	1376	Q9UKJ3
QHHAAAAAAAIGIHP	GPATCH8	1381	Q9UKJ3
AHSHRDFQPVLHLVA	COL18A1	1571	P39060
PAHRVVLAAASHFFN	KLHL7	56	Q8IXQ5
HHAQAHKALFGIFIP	POLE	1491	Q07864
LAQATHNFLRGLHFH	PLA2G4B	566	P0C869
HVHVLPRKAGDFHRN	FHIT	96	P49789
HSAIRPFDQLFALHA	IL5RA	221	Q01344
LHGRVFQLHVAHEFP	LACTBL1	431	A8MY62
PVFTRSAFAAVLHHH	DOCK9	691	Q9BZ29
HRLPLEAHISHFIHN	DENND4B	346	O75064
RVAFAAVRSHHHEPA	CBLN3	71	Q6UW01
EPADARFLNLIHHAA	FAM183BP	61	Q6ZVS7
LHHEHAARQGAVPAA	PRDM13	171	Q9H4Q3
LTRQLVHIFAHEPAH	IPO13	746	O94829
FSAAHALREHLNAAP	ORC3	581	Q9UBD5
VARHAAPHVHILLAN	OR52K2	266	Q8NGK3
APLQHRHVLAAAAAA	MIDN	161	Q504T8
QNRVAHVHPHAFRDL	RTN4R	211	Q9BZR6
HAQPHHLLLPAAAAA	RSBN1L	136	Q6PCB5
EPADARFLNLIHHAA	FAM183A	61	A6NL82
LGRHHHAAAAAAQTP	SIX4	91	Q9UIU6
HLAIQRHPHFRGLFN	ST6GALNAC2	71	Q9UJ37
HQVHRVQFVHRAHPA	POM121L2	36	Q96KW2
HAPFLALHRQVHAAA	REPIN1	96	Q9BWE0
HEVHRPSHFLNFALL	PRPF8	2306	Q6P2Q9
LAHHRLSHTGERPFA	ZNF497	401	Q6ZNH5
SHRALLERHLAAHPA	ZBTB45	496	Q96K62
RPALHFHLSHLHNVV	ZFHX2	1021	Q9C0A1
IHVFAVLLHAHLAGR	MOXD1	381	Q6UVY6
QSHPHLVAEAFRALA	SPOPL	361	Q6IQ16
RPFSALHDFHGHILA	HIVEP3	2156	Q5T1R4
FRVLNDFLAHHVHIP	WDFY4	1701	Q6ZS81
AHAHNHLRAPAFHQL	ZSWIM8	1746	A7E2V4
ALARHQAVHTADRPH	ZNF316	471	A6NFI3
HLAAPACLFSAHHNR	MST1R	156	Q04912
THTNPAALRIAHRAH	AMDHD2	271	Q9Y303