Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH6 DNAH9	4.66e-05	18	79	3	GO:0008569
GeneOntologyMolecularFunction	transmembrane transporter binding	TCAF2 ABCC8 EIF3E ACTN4 ACTN1 TRAPPC2	6.18e-05	172	79	6	GO:0044325
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH9 DNAH10 MYO18B DNAH6 DNAH9	1.05e-04	118	79	5	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	MYH9 MDN1 EP400 DNAH10 VWA8 ABCC8 HELZ2 BTAF1 DNAH6 DNAH9	1.50e-04	614	79	10	GO:0140657
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DNAH6 DNAH9	1.82e-04	28	79	3	GO:0051959
GeneOntologyMolecularFunction	ATP hydrolysis activity	MDN1 DNAH10 VWA8 ABCC8 HELZ2 BTAF1 DNAH6 DNAH9	3.52e-04	441	79	8	GO:0016887
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH10 DNAH6 DNAH9	4.20e-04	37	79	3	GO:0045505
GeneOntologyCellularComponent	axonemal dynein complex	DNAH10 DNAH6 DNAH9	1.17e-04	25	80	3	GO:0005858
GeneOntologyCellularComponent	postsynaptic cytoskeleton	ITSN1 SPTBN2 ACTN4	1.32e-04	26	80	3	GO:0099571
GeneOntologyCellularComponent	dendritic spine	TANC2 ITSN1 KCNN2 ACTN1 APP OPHN1	3.33e-04	242	80	6	GO:0043197
GeneOntologyCellularComponent	neuron spine	TANC2 ITSN1 KCNN2 ACTN1 APP OPHN1	3.71e-04	247	80	6	GO:0044309
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYH9 SPTBN2 ACTN4 ACTN1	4.48e-04	93	80	4	GO:0030864
GeneOntologyCellularComponent	inner dynein arm	DNAH10 DNAH6	6.38e-04	10	80	2	GO:0036156
GeneOntologyCellularComponent	TRAPPII protein complex	TRAPPC2B TRAPPC2	9.31e-04	12	80	2	GO:1990071
GeneOntologyCellularComponent	TRAPPIII protein complex	TRAPPC2B TRAPPC2	9.31e-04	12	80	2	GO:1990072
GeneOntologyCellularComponent	fascia adherens	DSP ACTN1	1.10e-03	13	80	2	GO:0005916
GeneOntologyCellularComponent	dynein complex	DNAH10 DNAH6 DNAH9	1.16e-03	54	80	3	GO:0030286
GeneOntologyCellularComponent	myosin complex	MYH9 MYH16 MYO18B	1.50e-03	59	80	3	GO:0016459
GeneOntologyCellularComponent	cortical cytoskeleton	MYH9 SPTBN2 ACTN4 ACTN1	1.52e-03	129	80	4	GO:0030863
GeneOntologyCellularComponent	actin cytoskeleton	MYH9 ITSN1 SPTBN2 ACTN4 MYH16 ACTN1 MYO18B OPHN1	1.61e-03	576	80	8	GO:0015629
GeneOntologyCellularComponent	postsynapse	TANC2 INPP4A ITSN1 SPTBN2 EIF3E KCNN2 ACTN4 ACTN1 APP GPR179 OPHN1	1.67e-03	1018	80	11	GO:0098794
GeneOntologyCellularComponent	cell-cell junction	MYH9 CLDN24 DSP SPTBN2 ACTN4 CLDN22 ACTN1 APP	1.89e-03	591	80	8	GO:0005911
GeneOntologyCellularComponent	TRAPP complex	TRAPPC2B TRAPPC2	1.90e-03	17	80	2	GO:0030008
GeneOntologyCellularComponent	pseudopodium	ACTN4 ACTN1	2.13e-03	18	80	2	GO:0031143
GeneOntologyCellularComponent	platelet alpha granule lumen	ACTN4 ACTN1 APP	2.17e-03	67	80	3	GO:0031093
GeneOntologyCellularComponent	postsynaptic actin cytoskeleton	ITSN1 ACTN4	2.37e-03	19	80	2	GO:0098871
GeneOntologyCellularComponent	Z disc	KCNN2 ACTN4 ACTN1 MYO18B	2.70e-03	151	80	4	GO:0030018
GeneOntologyCellularComponent	brush border	PLB1 MYH9 ACTN1 ENPEP	2.77e-03	152	80	4	GO:0005903
GeneOntologyCellularComponent	phagocytic vesicle	PIK3R4 MPO MYH9 MPEG1	3.11e-03	157	80	4	GO:0045335
GeneOntologyCellularComponent	I band	KCNN2 ACTN4 ACTN1 MYO18B	3.80e-03	166	80	4	GO:0031674
GeneOntologyCellularComponent	glutamatergic synapse	TANC2 ARHGAP22 INPP4A ITSN1 SPTBN2 PGRMC2 KCNN2 ACTN1 OPHN1	3.95e-03	817	80	9	GO:0098978
GeneOntologyCellularComponent	anchoring junction	ARHGAP22 MYH9 CLDN24 DSP SPTBN2 SRP68 ACTN4 CLDN22 ACTN1 APP	4.00e-03	976	80	10	GO:0070161
GeneOntologyCellularComponent	myosin filament	MYH9 MYO18B	4.10e-03	25	80	2	GO:0032982
MousePheno	hyperchylomicronemia	LMF1 PLVAP	2.00e-05	2	63	2	MP:0009699
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH10 VWA8 DNAH6 DNAH9	2.31e-09	14	79	5	IPR011704
Domain	AAA_5	MDN1 DNAH10 VWA8 DNAH6 DNAH9	2.31e-09	14	79	5	PF07728
Domain	AAA+_ATPase	MDN1 DNAH10 VWA8 ABCC8 HELZ2 DNAH6 DNAH9	2.55e-06	144	79	7	IPR003593
Domain	AAA	MDN1 DNAH10 VWA8 ABCC8 HELZ2 DNAH6 DNAH9	2.55e-06	144	79	7	SM00382
Domain	Spectrin_repeat	DSP SPTBN2 ACTN4 ACTN1	6.50e-06	29	79	4	IPR002017
Domain	Spectrin/alpha-actinin	DSP SPTBN2 ACTN4 ACTN1	9.74e-06	32	79	4	IPR018159
Domain	SPEC	DSP SPTBN2 ACTN4 ACTN1	9.74e-06	32	79	4	SM00150
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	IPR013602
Domain	DHC_N2	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	PF08393
Domain	MT	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	PF12777
Domain	AAA_8	DNAH10 DNAH6 DNAH9	2.56e-05	14	79	3	PF12780
Domain	DHC_fam	DNAH10 DNAH6 DNAH9	3.19e-05	15	79	3	IPR026983
Domain	Dynein_heavy_dom	DNAH10 DNAH6 DNAH9	3.19e-05	15	79	3	IPR004273
Domain	Dynein_heavy	DNAH10 DNAH6 DNAH9	3.19e-05	15	79	3	PF03028
Domain	Amyloid_glyco_E2_domain	APLP1 APP	5.29e-05	3	79	2	IPR024329
Domain	A4_EXTRA	APLP1 APP	5.29e-05	3	79	2	PS00319
Domain	Amyloid_glyco_heparin-bd	APLP1 APP	5.29e-05	3	79	2	IPR015849
Domain	APP_Cu_bd	APLP1 APP	5.29e-05	3	79	2	PF12924
Domain	APP_E2	APLP1 APP	5.29e-05	3	79	2	PF12925
Domain	APP_amyloid	APLP1 APP	5.29e-05	3	79	2	PF10515
Domain	A4_INTRA	APLP1 APP	5.29e-05	3	79	2	PS00320
Domain	Amyloid_glyco	APLP1 APP	5.29e-05	3	79	2	IPR008155
Domain	Amyloid_glyco_extra	APLP1 APP	5.29e-05	3	79	2	IPR008154
Domain	-	APLP1 APP	5.29e-05	3	79	2	3.90.570.10
Domain	-	APLP1 APP	5.29e-05	3	79	2	3.30.1490.140
Domain	APP_amyloid_C	APLP1 APP	5.29e-05	3	79	2	IPR019543
Domain	Amyloid_glyco_extracell_CS	APLP1 APP	5.29e-05	3	79	2	IPR019744
Domain	Amyloid_glyco_intracell_CS	APLP1 APP	5.29e-05	3	79	2	IPR019745
Domain	Amyloid_glyco_Cu-bd	APLP1 APP	5.29e-05	3	79	2	IPR011178
Domain	APP_N	APLP1 APP	5.29e-05	3	79	2	PF02177
Domain	A4_EXTRA	APLP1 APP	5.29e-05	3	79	2	SM00006
Domain	Actinin_actin-bd_CS	SPTBN2 ACTN4 ACTN1	1.21e-04	23	79	3	IPR001589
Domain	Spectrin	SPTBN2 ACTN4 ACTN1	1.21e-04	23	79	3	PF00435
Domain	ACTININ_2	SPTBN2 ACTN4 ACTN1	1.21e-04	23	79	3	PS00020
Domain	ACTININ_1	SPTBN2 ACTN4 ACTN1	1.21e-04	23	79	3	PS00019
Domain	PH	ARHGAP22 IRS4 FGD2 ITSN1 SPTBN2 AKT2 OPHN1	1.74e-04	278	79	7	SM00233
Domain	PH_DOMAIN	ARHGAP22 IRS4 FGD2 ITSN1 SPTBN2 AKT2 OPHN1	1.78e-04	279	79	7	PS50003
Domain	PH_domain	ARHGAP22 IRS4 FGD2 ITSN1 SPTBN2 AKT2 OPHN1	1.82e-04	280	79	7	IPR001849
Domain	P-loop_NTPase	TANC2 MYH9 MDN1 EP400 DNAH10 VWA8 ABCC8 HELZ2 BTAF1 MYO18B DNAH6 DNAH9	2.20e-04	848	79	12	IPR027417
Domain	-	ARHGAP22 IRS4 FGD2 ITSN1 SPTBN2 MTMR3 AKT2 OPHN1	2.45e-04	391	79	8	2.30.29.30
Domain	EF-hand_Ca_insen	ACTN4 ACTN1	2.62e-04	6	79	2	IPR014837
Domain	EFhand_Ca_insen	ACTN4 ACTN1	2.62e-04	6	79	2	PF08726
Domain	SUN_dom	SUN3 HECTD1	3.66e-04	7	79	2	IPR012919
Domain	Sad1_UNC	SUN3 HECTD1	3.66e-04	7	79	2	PF07738
Domain	PH	ARHGAP22 FGD2 ITSN1 SPTBN2 AKT2 OPHN1	4.19e-04	229	79	6	PF00169
Domain	PH_dom-like	ARHGAP22 IRS4 FGD2 ITSN1 SPTBN2 MTMR3 AKT2 OPHN1	4.35e-04	426	79	8	IPR011993
Domain	DHC_N1	DNAH10 DNAH9	4.87e-04	8	79	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH10 DNAH9	4.87e-04	8	79	2	IPR013594
Domain	CH	SPTBN2 ACTN4 ACTN1	2.63e-03	65	79	3	SM00033
Domain	Myosin-like_IQ_dom	MYH9 MYO18B	2.88e-03	19	79	2	IPR027401
Domain	-	MYH9 MYO18B	2.88e-03	19	79	2	4.10.270.10
Domain	CH	SPTBN2 ACTN4 ACTN1	3.25e-03	70	79	3	PF00307
Domain	-	SPTBN2 ACTN4 ACTN1	3.39e-03	71	79	3	1.10.418.10
Domain	CH	SPTBN2 ACTN4 ACTN1	3.66e-03	73	79	3	PS50021
Domain	Claudin_CS	CLDN24 CLDN22	3.86e-03	22	79	2	IPR017974
Domain	CLAUDIN	CLDN24 CLDN22	3.86e-03	22	79	2	PS01346
Domain	CH-domain	SPTBN2 ACTN4 ACTN1	3.95e-03	75	79	3	IPR001715
Domain	-	MDN1 EP400 DNAH10 VWA8 ABCC8 HELZ2 BTAF1 DNAH6 DNAH9	4.18e-03	746	79	9	3.40.50.300
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 MYH9 IRS4 MDN1 DSP SPTBN2 EIF3E HELZ2 SRP68 ACTN4 ACTN1 HECTD1 SON	4.36e-09	653	82	13	22586326
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SART3 EP400 VWA8 SPTBN2 SCAPER HECTD1 FOXJ3	2.61e-08	130	82	7	12421765
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH10 DNAH6 DNAH9	5.04e-08	4	82	3	11175280
Pubmed	Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system.	CNTN3 APLP1 APP	1.26e-07	5	82	3	18272596
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	LMF1 SLC12A2 EP400 ITSN1 PGRMC2 EIF3E SRP68 FASTKD5 AKT2 HECTD1 ADCY9	1.22e-06	733	82	11	34672954
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	MYH9 SLC12A2 DSP SPTBN2 EIF3E ACTN4 ACTN1 DNAH9	1.25e-06	333	82	8	32665550
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PIK3R4 MPO SART3 MYH9 MDN1 EP400 DSP LRSAM1 EIF3E SRP68 ACTN4 ACTN1 PGD SON	3.15e-06	1353	82	14	29467282
Pubmed	FCHo proteins are nucleators of clathrin-mediated endocytosis.	MYH9 ITSN1 ACTN4	3.55e-06	13	82	3	20448150
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	MYH9 IRS4 DSP SRP68 ACTN4 ACTN1	4.33e-06	179	82	6	36261009
Pubmed	Mechanical regulation of glycolysis via cytoskeleton architecture.	VWA8 ACTN4 ACTN1	4.51e-06	14	82	3	32051585
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MRPL17 SART3 MYH9 MDN1 DSP SPTBN2 EIF3E SCAPER ACTN4 ACTN1 DNAH6	4.86e-06	847	82	11	35235311
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	IRS4 MDN1 SLC12A2 EP400 DSP SPTBN2 PGRMC2 ACTN4 BTAF1 ACTN1 APP SON	4.96e-06	1024	82	12	24711643
Pubmed	Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.	APLP1 APP	5.49e-06	2	82	2	30630900
Pubmed	Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking.	ACTN4 ACTN1	5.49e-06	2	82	2	34010028
Pubmed	An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.	ACTN4 ACTN1	5.49e-06	2	82	2	23557398
Pubmed	Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.	DNAH10 DNAH6	5.49e-06	2	82	2	15937072
Pubmed	The E2 domains of APP and APLP1 share a conserved mode of dimerization.	APLP1 APP	5.49e-06	2	82	2	21574595
Pubmed	Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology.	ACTN4 ACTN1	5.49e-06	2	82	2	20037648
Pubmed	HAMLET binding to α-actinin facilitates tumor cell detachment.	ACTN4 ACTN1	5.49e-06	2	82	2	21408150
Pubmed	Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells.	ACTN4 ACTN1	5.49e-06	2	82	2	28797528
Pubmed	α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.	ACTN4 ACTN1	5.49e-06	2	82	2	23454549
Pubmed	Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.	APLP1 APP	5.49e-06	2	82	2	8576160
Pubmed	Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.	FRA10AC1 APP	5.49e-06	2	82	2	26252872
Pubmed	Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not.	TRAPPC2B TRAPPC2	5.49e-06	2	82	2	14597397
Pubmed	Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda.	TRAPPC2B TRAPPC2	5.49e-06	2	82	2	10431248
Pubmed	Alpha-actinin 1 and alpha-actinin 4: contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells.	ACTN4 ACTN1	5.49e-06	2	82	2	20156433
Pubmed	Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400).	TRAPPC2B TRAPPC2	5.49e-06	2	82	2	12939648
Pubmed	Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis.	CNTN3 APP	5.49e-06	2	82	2	31318883
Pubmed	Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome.	APLP1 APP	5.49e-06	2	82	2	24740518
Pubmed	Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein.	APLP1 APP	5.49e-06	2	82	2	16344553
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PIK3R4 TANC2 SART3 MYH9 DSP INPP4A ITSN1 SPTBN2 SCAPER SRP68 ACTN4 ACTN1 DNAH6 OPHN1	5.99e-06	1431	82	14	37142655
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	WDR19 MRPL17 SART3 MDN1 SLC12A2 VWA8 ITSN1 SPTBN2 PGRMC2 FASTKD5 AKT2 APP PGD ADCY9	9.25e-06	1487	82	14	33957083
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WDR19 PIK3R4 ACAD8 DSP ITSN1 LRSAM1 SPTBN2 MTMR3 ACTN4 ACTN1 APP HECTD1 CHUK	9.40e-06	1285	82	13	35914814
Pubmed	DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.	MYH9 DSP ACTN4 ACTN1	1.54e-05	63	82	4	37052853
Pubmed	Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.	MYH9 ACTN4 ACTN1	1.63e-05	21	82	3	12202484
Pubmed	Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.	APLP1 APP	1.64e-05	3	82	2	11050115
Pubmed	Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.	ACTN4 ACTN1	1.64e-05	3	82	2	16751418
Pubmed	Differential role of APP and APLPs for neuromuscular synaptic morphology and function.	APLP1 APP	1.64e-05	3	82	2	24998676
Pubmed	α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.	ACTN4 ACTN1	1.64e-05	3	82	2	21784188
Pubmed	Regulation of gene expression by the APP family in the adult cerebral cortex.	APLP1 APP	1.64e-05	3	82	2	34997052
Pubmed	Amyloid precursor proteins are constituents of the presynaptic active zone.	APLP1 APP	1.64e-05	3	82	2	23815291
Pubmed	Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.	ACTN4 ACTN1	1.64e-05	3	82	2	23890175
Pubmed	Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference.	APLP1 APP	1.64e-05	3	82	2	16889988
Pubmed	APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.	APLP1 APP	1.64e-05	3	82	2	32891188
Pubmed	Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.	APLP1 APP	1.64e-05	3	82	2	19126676
Pubmed	APLP2 regulates neuronal stem cell differentiation during cortical development.	APLP1 APP	1.64e-05	3	82	2	23345401
Pubmed	Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein.	APLP1 APP	1.64e-05	3	82	2	15561424
Pubmed	TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9.	MYH9 ACTN4	1.64e-05	3	82	2	30258071
Pubmed	Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.	APLP1 APP	1.64e-05	3	82	2	9890987
Pubmed	Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis.	ACTN4 ACTN1	1.64e-05	3	82	2	16951376
Pubmed	Homo- and heterodimerization of APP family members promotes intercellular adhesion.	APLP1 APP	1.64e-05	3	82	2	16193067
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	MYH9 IRS4 MDN1 SLC12A2 PGRMC2 EIF3E ACTN4 ACTN1	1.92e-05	484	82	8	31995728
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	SART3 IRS4 MDN1 EIF3E SRP68 ACTN4 ACTN1 HECTD1 SON	1.98e-05	638	82	9	33239621
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MYH9 IRS4 MDN1 SLC12A2 DSP KRT32 EIF3E ACTN4 ACTN1 PGD	2.03e-05	807	82	10	30575818
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH9 IRS4 MDN1 DSP PGRMC2 EIF3E ACTN4 ACTN1 CHUK	2.21e-05	647	82	9	26618866
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PIK3R4 SART3 MYH9 IRS4 MDN1 DNAH10 DSP EIF3E SRP68 FASTKD5 ACTN4 MYO18B PGD	2.79e-05	1425	82	13	30948266
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	MYH9 DSP SPTBN2	2.80e-05	25	82	3	30309841
Pubmed	Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.	MYH9 HELZ2 ACTN4 ACTN1 PGD	3.11e-05	152	82	5	16009940
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SART3 FRA10AC1 MYH9 IRS4 MDN1 DSP ITSN1 SPTBN2 ACTN4 ACTN1 DNAH6 CHUK TRAPPC2	3.15e-05	1442	82	13	35575683
Pubmed	A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.	MYH9 DSP ACTN4 ACTN1 PGD	3.20e-05	153	82	5	27462432
Pubmed	Insulin signaling via Akt2 switches plakophilin 1 function from stabilizing cell adhesion to promoting cell proliferation.	DSP AKT2	3.28e-05	4	82	2	23444369
Pubmed	Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.	APLP1 APP	3.28e-05	4	82	2	14983046
Pubmed	Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease.	APLP1 APP	3.28e-05	4	82	2	15208260
Pubmed	A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1.	TRAPPC2B TRAPPC2	3.28e-05	4	82	2	11134351
Pubmed	cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.	APLP1 APP	3.28e-05	4	82	2	8894693
Pubmed	Tight junction-based epithelial microenvironment and cell proliferation.	CLDN24 CLDN22	3.28e-05	4	82	2	19029935
Pubmed	Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.	ACTN4 ACTN1	3.28e-05	4	82	2	23515331
Pubmed	Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.	ACTN4 ACTN1	3.28e-05	4	82	2	1629252
Pubmed	An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.	ACTN4 ACTN1	3.28e-05	4	82	2	2116421
Pubmed	Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors.	ACTN4 ACTN1	3.28e-05	4	82	2	22351778
Pubmed	Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.	APLP1 APP	3.28e-05	4	82	2	16314516
Pubmed	CLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4.	ACTN4 ACTN1	3.28e-05	4	82	2	10753915
Pubmed	Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.	ACTN4 ACTN1	3.28e-05	4	82	2	16807302
Pubmed	Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype.	APLP1 APP	3.28e-05	4	82	2	34008862
Pubmed	Interactions of a hemidesmosome component and actinin family members.	ACTN4 ACTN1	3.28e-05	4	82	2	11739652
Pubmed	Crystal structures of the Dab homology domains of mouse disabled 1 and 2.	APLP1 APP	3.28e-05	4	82	2	12826668
Pubmed	Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.	APLP1 APP	3.28e-05	4	82	2	10460257
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	ACTN4 ACTN1	3.28e-05	4	82	2	15988023
Pubmed	WDFY4 is required for cross-presentation in response to viral and tumor antigens.	MYH9 VWA8 MPEG1 ACTN4 ACTN1	3.52e-05	156	82	5	30409884
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SART3 MYH9 IRS4 SPTBN2 ACTN4 ACTN1	4.80e-05	274	82	6	34244482
Pubmed	E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1.	DSP ACTN4 ACTN1	5.41e-05	31	82	3	33777788
Pubmed	Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions.	APLP1 APP	5.47e-05	5	82	2	17727637
Pubmed	Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter.	APLP1 APP	5.47e-05	5	82	2	17709753
Pubmed	Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.	ACTN4 ACTN1	5.47e-05	5	82	2	15841212
Pubmed	Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.	APLP1 APP	5.47e-05	5	82	2	10081969
Pubmed	Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.	ITSN1 LRSAM1	5.47e-05	5	82	2	15256501
Pubmed	APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.	APLP1 APP	5.47e-05	5	82	2	28450540
Pubmed	The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.	ACTN4 ACTN1	5.47e-05	5	82	2	12837758
Pubmed	Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.	ACTN4 ACTN1	5.47e-05	5	82	2	19943616
Pubmed	The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.	ACTN4 ACTN1	5.47e-05	5	82	2	16501493
Pubmed	Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling.	APLP1 APP	5.47e-05	5	82	2	21293490
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 MDN1 GRTP1 EP400 VWA8 HELZ2 MTMR3 AKT2 BTAF1 HECTD1 ADCY9	5.65e-05	1105	82	11	35748872
Pubmed	Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.	MYH9 ACTN4 ACTN1	7.17e-05	34	82	3	20391533
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MPO PLB1 MYH9 EP400 VWA8 DSP EIF3E SRP68 PGD	7.21e-05	754	82	9	35906200
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SART3 MYH9 IRS4 MDN1 DSP SPTBN2 EIF3E SRP68 ACTN4 ACTN1 PGD	8.00e-05	1149	82	11	35446349
Pubmed	Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.	ACTN4 ACTN1	8.19e-05	6	82	2	18425115
Pubmed	The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.	ACTN4 ACTN1	8.19e-05	6	82	2	22693585
Pubmed	Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.	APLP1 APP	8.19e-05	6	82	2	14699153
Pubmed	Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis.	APLP1 APP	8.19e-05	6	82	2	19726636
Pubmed	ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.	MYH9 SPTBN2	8.19e-05	6	82	2	37069398
Interaction	NEFM interactions	SART3 MYH9 VWA8 DSP KRT32 ITSN1 FASTKD5 DNAH9	8.74e-07	190	80	8	int:NEFM
Interaction	SIRT7 interactions	SART3 MYH9 IRS4 MDN1 DSP SPTBN2 EIF3E HELZ2 SRP68 ACTN4 ACTN1 APP HECTD1 SON	1.22e-06	744	80	14	int:SIRT7
GeneFamily	Dyneins, axonemal	DNAH10 DNAH6 DNAH9	1.76e-05	17	55	3	536
GeneFamily	Actinins	ACTN4 ACTN1	5.43e-05	4	55	2	1112
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP22 FGD2 ITSN1 SPTBN2 AKT2	4.01e-04	206	55	5	682
GeneFamily	Myosin heavy chains	MYH9 MYH16	9.30e-04	15	55	2	1098
GeneFamily	Claudins	CLDN24 CLDN22	2.21e-03	23	55	2	488
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	FGD2 MTMR3	3.99e-03	31	55	2	81
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	INPP4A ITSN1	5.36e-03	36	55	2	823
Coexpression	ANDERSON_BLOOD_CN54GP140_ADJUVANTED_WITH_GLA_AF_AGE_18_45YO_1DY_DN	FRA10AC1 MYH9 MTMR3 FOXJ3 PGD SON	2.80e-07	85	82	6	M41085
Coexpression	GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	ENOSF1 AKT2 BTAF1 HECTD1 FOXJ3 ZNF891 ZNF529	2.34e-06	191	82	7	M4935
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAH10 DSP KRT32 DNAH6 DNAH9	8.83e-06	151	82	5	8216462e723fec2797387929dde095370947e10a
ToppCell	droplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ARHGAP22 FGD2 APLP1 OPHN1	1.20e-05	161	82	5	f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCell	droplet-Lung-nan-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ARHGAP22 FGD2 APLP1 OPHN1	1.20e-05	161	82	5	110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	ARHGAP22 PLB1 FGD2 ITSN1 MPEG1	1.40e-05	166	82	5	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MYH9 ACTN1 APP PGD	1.61e-05	171	82	5	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MYH9 ACTN1 APP PGD	1.61e-05	171	82	5	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNV1 PLB1 DSP SPTBN2 ANXA10	1.70e-05	173	82	5	1b2508cc890430bd4b2cf232c633928edb86c57e
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 DSP SPTBN2 C6orf15 SUN3	1.75e-05	174	82	5	97d4a40b536a67fa52f055eab26106d041bf3220
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 DSP SPTBN2 C6orf15 SUN3	1.75e-05	174	82	5	f9f399244c7d12caf8118ec3117d477a39e35c3b
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMF1 SLC12A2 FGD2 MPEG1 ADCY9	1.75e-05	174	82	5	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 DSP SPTBN2 C6orf15 SUN3	1.75e-05	174	82	5	e8440eea7c81864defa57c89e9b569ad8033e5c5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MYH9 ACTN1 APP PGD	1.90e-05	177	82	5	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MYH9 ACTN1 APP PGD	1.90e-05	177	82	5	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KCNV1 DSP ABCC8 SPTBN2 APLP1	2.01e-05	179	82	5	06f92c884189197c86793191c05f65e34925c097
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNV1 PLB1 DSP KRT32 SPTBN2	2.12e-05	181	82	5	6b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNV1 PLB1 DSP KRT32 SPTBN2	2.12e-05	181	82	5	f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCell	droplet-Marrow-nan-21m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PLBD1 ACTN1 APP PGD	2.29e-05	184	82	5	d071f53ad9e957dc0f8ae9c53aaa31cfebcf815e
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAH ARHGAP22 DSP APLP1 APP	2.41e-05	186	82	5	1587667e5084ac43505d027af925ba711e228150
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR19 DNAH10 EPHX4 DNAH6 DNAH9	2.48e-05	187	82	5	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR19 DNAH10 EPHX4 DNAH6 DNAH9	2.48e-05	187	82	5	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO INPP4A ABCC8 APLP1 SON	2.54e-05	188	82	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF2 PLBD1 PLB1 KRT32 PGD	2.54e-05	188	82	5	b40146ed0af022422e6526116e5897c676ed9d71
ToppCell	facs-Marrow-KLS-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO ARHGAP22 LMF1 FGD2 MPEG1	2.60e-05	189	82	5	b28a0e2d5a5f512f9b137b162b195bdc3d5ee9ba
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPO PLBD1 DNAH10 ACTN1 PGD	2.67e-05	190	82	5	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP22 PLB1 FGD2 ITSN1 MPEG1	2.74e-05	191	82	5	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP22 PLB1 FGD2 ITSN1 MPEG1	2.74e-05	191	82	5	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP22 PLB1 FGD2 ITSN1 MPEG1	2.95e-05	194	82	5	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP22 PLB1 FGD2 ITSN1 MPEG1	2.95e-05	194	82	5	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MPO PLBD1 ACTN1 APP PGD	3.02e-05	195	82	5	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_3\|COVID-19_Mild / Disease condition and Cell class	MPO PLBD1 MYH9 MPEG1 PGD	3.10e-05	196	82	5	f245e929a286cb097130572e1027b4f01be8b04d
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 DSP ACTN4 ACTN1 APP	3.18e-05	197	82	5	f4dad4423384a2a25e064c849ffccf2811573be0
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 SLC12A2 ACTN4 APP SON	3.25e-05	198	82	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH9 SLC12A2 ACTN4 APP SON	3.25e-05	198	82	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH9 PLVAP KCNN2 APP EPHX4	3.25e-05	198	82	5	0c8ec287500c58938ecc0dbbbc5f6c7a48733fc6
ToppCell	LPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP22 FGD2 ABCC8 MPEG1	5.48e-05	112	82	4	9801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	WDR19 GRTP1 HELZ2 TRAPPC2	1.10e-04	134	82	4	9e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCell	facs-Heart-RV-24m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	1.88e-04	154	82	4	709e7eedec11e675c6bbd55940f91dea5f715f4c
ToppCell	facs-Heart-RV-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	1.88e-04	154	82	4	8c65d4ea787a75f20448b11beea571d7ec684721
ToppCell	facs-Heart-RV-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	1.88e-04	154	82	4	60e7c03d91ea87eb6226a744633cbe6efa9a9928
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 DNAH10 MPEG1 TMEM104	2.02e-04	157	82	4	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 DNAH10 CNTN3 DNAH9	2.17e-04	160	82	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 DNAH10 CNTN3 DNAH9	2.17e-04	160	82	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Fat-Mat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.22e-04	161	82	4	8c62ae3fcf304db0f71633e328ceba81a70f03c4
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MDN1 SCAPER CNTN3 OPHN1	2.22e-04	161	82	4	347edb0de10850b7d16c40945751033289289c9b
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MDN1 FGD2 PGBD1	2.28e-04	162	82	4	8a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNV1 DSP ABCC8 SPTBN2	2.28e-04	162	82	4	9f568836199a05f696294caac1ea3fa413984423
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 KCNV1 HECTD1 DNAH6	2.28e-04	162	82	4	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 SLC12A2 DNAH10 TMEM104	2.33e-04	163	82	4	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 C6orf15 CLDN22 EPHX4	2.33e-04	163	82	4	22fa5d017ff796394394d952ec151e2d1beb8248
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 SLC12A2 DNAH10 TMEM104	2.33e-04	163	82	4	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	droplet-Kidney-nan-21m-Myeloid-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.39e-04	164	82	4	d4cdcd61e8c28b3fb912cef8837cc1a49678a729
ToppCell	droplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 MDN1 FGD2	2.39e-04	164	82	4	a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 ITSN1 LRSAM1 MPEG1	2.50e-04	166	82	4	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 ITSN1 LRSAM1 MPEG1	2.50e-04	166	82	4	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP ABCC8 ANXA10 APLP1	2.50e-04	166	82	4	afba41e15478053f11815acf568d29187de75492
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 MPEG1 APP PGD	2.50e-04	166	82	4	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	COVID-19-APC-like-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	PLB1 ACAD8 ZNF852 MPEG1	2.56e-04	167	82	4	854a5dbd43f2b25825a71d37fd7779507783a99a
ToppCell	facs-Kidney-nan-3m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.56e-04	167	82	4	991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-7\|TCGA-Thryoid / Sample_Type by Project: Shred V9	FAM234B AKT2 PGD DNAH9	2.56e-04	167	82	4	01c42e555913b17e62846325cc17b3d8f92da1e1
ToppCell	facs-Kidney-nan-3m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.56e-04	167	82	4	f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCell	facs-Spleen-nan-24m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO FAH ABCC8 EIF3E	2.56e-04	167	82	4	9a8e291c082d7c26bab21df77bd36ce927032a70
ToppCell	facs-Kidney-nan-3m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.56e-04	167	82	4	934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNV1 PLBD1 MPEG1 ACTN1	2.61e-04	168	82	4	95416f352801ce42cc317565e7dfb00478c593e1
ToppCell	droplet-Lung-21m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 ARHGAP22 MPEG1 OPHN1	2.61e-04	168	82	4	aaafa7243c44e6852d92e3445335fc4a1018f416
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WDR19 FAH ARHGAP22 TCAF2	2.61e-04	168	82	4	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	droplet-Lung-21m-Hematologic-myeloid-interstitial_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 ARHGAP22 MPEG1 OPHN1	2.61e-04	168	82	4	06787d4f08ddf052127404a0ea6a85e1b048e206
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACAD8 PLVAP ABCC8 ANXA10	2.61e-04	168	82	4	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ENOSF1 DNAH10 DNAH6 DNAH9	2.67e-04	169	82	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 ACTN1 APP PGD	2.67e-04	169	82	4	1000eaf5158596b4898bedcc802b31db76b05a48
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 ACTN1 APP PGD	2.67e-04	169	82	4	83b854fa8fd9017df8f9207d9ced260eee98e8c1
ToppCell	droplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAH PLBD1 FGD2 MPEG1	2.74e-04	170	82	4	29deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCell	droplet-Thymus-nan-21m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAH PLBD1 FGD2 MPEG1	2.74e-04	170	82	4	dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 ACTN1 APP PGD	2.80e-04	171	82	4	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8\|TCGA-Liver / Sample_Type by Project: Shred V9	ACAD8 PLVAP VWA8 SPTBN2	2.80e-04	171	82	4	c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell	droplet-Thymus-nan-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.80e-04	171	82	4	25493a4a7b636920e2cfd984542cc500709c9dcf
ToppCell	droplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.80e-04	171	82	4	508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PLBD1 MYH9 PLVAP ACTN4	2.80e-04	171	82	4	bdd30100b74e012eec3090799c22635aa57fa91d
ToppCell	facs-Marrow-KLS-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.86e-04	172	82	4	979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCell	facs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.86e-04	172	82	4	f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLVAP FGD2 MPEG1	2.86e-04	172	82	4	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLVAP FGD2 MPEG1	2.86e-04	172	82	4	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLBD1 LMF1 FGD2 HYLS1	2.92e-04	173	82	4	28c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCell	droplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ARHGAP22 FGD2 OPHN1	2.92e-04	173	82	4	31ea04e65876c42b90245d280f0b6439bfffbace
ToppCell	facs-Heart-RA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.92e-04	173	82	4	4fa5f502fa3ff8f888e279f68a0dafd91b37f26f
ToppCell	droplet-Lung-nan-21m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ARHGAP22 FGD2 OPHN1	2.92e-04	173	82	4	1cff815536f620e32b9805666e1aa711462c2d25
ToppCell	facs-Heart-RA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.92e-04	173	82	4	5058cb5e3f2d57dbe947e1b113eb2bef7bf6dd7d
ToppCell	facs-Heart-RA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP22 PLBD1 FGD2 MPEG1	2.92e-04	173	82	4	ea406b47ff3ead992bc06f6b1707c76eee574782
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	2.99e-04	174	82	4	54166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	DNAH10 APP ZNF891 OPHN1	2.99e-04	174	82	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	2.99e-04	174	82	4	dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCell	facs-Spleen-nan-24m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO FAH FGD2 ABCC8	2.99e-04	174	82	4	a0641908ab6feaca5cd07142d7429983a2f68668
ToppCell	facs-Heart-LV-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PLBD1 FGD2 MPEG1	3.05e-04	175	82	4	5d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNV1 DSP ABCC8 SUN3	3.05e-04	175	82	4	c031da47ca63d1133e13530cbf779df9435e22cb
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PLBD1 PLVAP PGD	3.05e-04	175	82	4	b4ff5a74ad22addbdd848dde9ba93d63a0611543
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP22 PLBD1 FGD2 MPEG1	3.05e-04	175	82	4	4655d3daa95e8ffa7d5ee4180de06b2fec361bfb
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO PLBD1 PLVAP PGD	3.05e-04	175	82	4	27a8c6e398638ccdee90c44e2ca6f59acc206cbc
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNV1 DSP ABCC8 APLP1	3.12e-04	176	82	4	d54543510c804474c5c32e007cd699e75fc5aaba
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP22 PLBD1 FGD2 MPEG1	3.12e-04	176	82	4	7b5e50eb144bf43ca0cf354a466eb58b976a79f1
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	DNAH10 APP ZNF891 OPHN1	3.12e-04	176	82	4	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP22 PLBD1 FGD2 MPEG1	3.12e-04	176	82	4	7d1e2627d7ec5ddd6c87c55d2a6879255b76949e
Disease	X-linked spondyloepiphyseal dysplasia tarda (implicated_via_orthology)	TRAPPC2B TRAPPC2	7.26e-06	2	80	2	DOID:0080362 (implicated_via_orthology)
Disease	Alzheimer disease type 1	MPO APP	4.34e-05	4	80	2	cv:C1863052
Disease	ALZHEIMER DISEASE, FAMILIAL, 1	MPO APP	4.34e-05	4	80	2	104300
Disease	Alzheimer's disease 1 (is_implicated_in)	MPO APP	4.34e-05	4	80	2	DOID:0080348 (is_implicated_in)
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN4 ACTN1	7.22e-05	5	80	2	DOID:0111128 (implicated_via_orthology)
Disease	spondyloepiphyseal dysplasia congenita (implicated_via_orthology)	TRAPPC2B TRAPPC2	1.08e-04	6	80	2	DOID:14789 (implicated_via_orthology)
Disease	Early-onset autosomal dominant Alzheimer disease	MPO APP	1.51e-04	7	80	2	cv:CN043596
Disease	Alzheimer's disease 1 (implicated_via_orthology)	APLP1 APP	1.51e-04	7	80	2	DOID:0080348 (implicated_via_orthology)
Disease	isobutyrylcarnitine measurement	ACAD8 SCAPER	2.01e-04	8	80	2	EFO_0021023
Disease	Alzheimer disease	MPO APP	2.01e-04	8	80	2	cv:C0002395
Disease	left atrial function	DSP MYO18B	1.47e-03	21	80	2	EFO_0004294
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	FGD2 MTMR3	1.93e-03	24	80	2	DOID:10595 (implicated_via_orthology)
Disease	Left ventricular mass to end-diastolic volume ratio	LMF1 MYO18B	2.09e-03	25	80	2	EFO_0010556
Disease	Brain Diseases	MPO APP	2.09e-03	25	80	2	C0006111
Disease	Encephalopathies	MPO APP	2.44e-03	27	80	2	C0085584
Disease	TYPE 2 DIABETES MELLITUS	ABCC8 AKT2	2.62e-03	28	80	2	125853
Disease	Hyalinosis, Segmental Glomerular	MYH9 ACTN4	2.62e-03	28	80	2	C0086432
Disease	Type 2 diabetes mellitus	ABCC8 AKT2	2.62e-03	28	80	2	cv:C0011860

Protein segments in the cluster

Peptide	Gene	Start	Entry
REEWMRAIQMVANSL	AKT2	96	P31751
LEEMQWMATDFAQER	EP400	816	Q96L91
LNLDLNEMENWTMGL	CLDN24	36	A6NM45
FNNWMEGAMEDLQDT	ACTN1	521	P12814
AMAAQDAMVLWEACQ	ANXA10	171	Q9UJ72
ERLDNGTWVLMDQHM	APOBEC3B	221	Q9UH17
AAREMAPNMAEWDQK	ACAD8	56	Q9UKU7
MSQVMREWEEAERQA	APP	406	P05067
RAAPFNNWMESAMED	ACTN4	536	O43707
NNWMESAMEDLQDMF	ACTN4	541	O43707
NEVMREWAMADNQSK	APLP1	326	P51693
MAQDEMAQAFEDWNK	PGD	211	P52209
LSEANRRLWMEAMDG	OPHN1	351	O60890
VMLRNDQDTLMARWT	INPP4A	496	Q96PE3
WDNLRNVDMGRVMEL	MPEG1	51	Q2M385
DPRWNMQALDMIRNL	MDN1	2596	Q9NU22
WELDDNVMGQEMLSL	GPR179	1481	Q6PRD1
MAEMDERFQQILSWQ	LRSAM1	421	Q6UWE0
LLWGENDAFMEVEMA	EPHX4	301	Q8IUS5
FMVDNGADDWRIAMT	KCNN2	196	Q9H2S1
EANEEQGNSMMNLDW	CHUK	726	O15111
RDVEEWFNMQMEELN	KRT32	281	Q14532
TLMMDANQRWDVPEA	ENOSF1	246	Q7L5Y1
NMALMSAELSWLDLQ	KCNV1	226	Q6PIU1
ENHRFLWNEEDEMDM	FRA10AC1	111	Q70Z53
DAIMQMWLNARRDLD	PLVAP	96	Q9BX97
NAVQMESVREWEMQF	PGRMC2	176	O15173
QERSLMFMQWGQLLD	MPO	246	P05164
QQSTDERMDAMLLWQ	FAM223A	41	Q8IWN6
SLRWALMEGQMAQLQ	FAM234B	581	A2RU67
ADEWLMKNMDPLNDN	MYH9	581	P35579
ETDWQMRDQMLLEDV	ENPEP	431	Q07075
LSWQRVRVANMMADS	PLBD1	321	Q6P4A8
WQMMAAAAEDRLGEA	C6orf15	116	Q6UXA7
LNLDLNEMENWTMGL	CLDN22	36	Q8N7P3
VEMMRQQGTLSDAEW	DNAH6	3376	Q9C0G6
EWLQMGQGDERDMQL	HECTD1	11	Q9ULT8
VWEMNMDQLLLVADL	FASTKD5	236	Q7L8L6
WANMDPEERMLAAAT	HYLS1	11	Q96M11
HDWNPMRDLQAMDRA	BTAF1	1726	O14981
LMESMRQADLKNWSL	FOXJ3	486	Q9UPW0
RQQRAEMDMVAWGVD	DSP	196	P15924
IWALADMNNDGRMDQ	ITSN1	61	Q15811
RVWMVLSGAQAQMDQ	GRTP1	76	Q5TC63
MRVVDDFNNNMLWFN	ADCY9	1146	O60503
EILMQNWDAAMEDLT	EIF3E	176	P60228
LELQARSQEEMISWM	FGD2	396	Q7Z6J4
FGMVLMNDWSARDIQ	FAH	226	P16930
LRMLMDDADVAAWQN	DNAH9	3426	Q9NYC9
RDMSMASWLNLAEIA	HELZ2	791	Q9BYK8
GDVDALWVENMNSVM	DNAH10	2191	Q8IVF4
LWVENMNSVMDDNRL	DNAH10	2196	Q8IVF4
CNNMQKARELWDSIM	SART3	486	Q15020
MSMDWNDVLADYEAR	SCAPER	486	Q9BY12
RWQLNGSDIDMSMEH	CNTN3	61	Q9P232
ERMGFDMNNAWRISN	MTMR3	166	Q13615
ELWMQVDDCVVAQNM	IRS4	306	O14654
MTRDLFNEWLMQVDA	TIGD6	256	Q17RP2
FNEWLMQVDARMKRA	TIGD6	261	Q17RP2
WDEMMQAVARLAAEP	TCAF2	691	A6NFQ2
RGDNWMLMLRDTIED	THNSL2	456	Q86YJ6
LEWEDFQQRMENLSM	TANC2	736	Q9HCD6
QLDNGMRDQMSFLLW	WDR19	91	Q8NEZ3
MIDVAMNNAWQLHRA	PGBD1	766	Q96JS3
AEMAIALWNNMLEPV	PLB1	1356	Q6P1J6
LVLMDAERAWSYAMQ	SRP68	126	Q9UHB9
MASSQRDMEDWVQAI	ARHGAP22	126	Q7Z5H3
SNYLNWMVRNLADME	ABCC8	1291	Q09428
WMVRNLADMELQLGA	ABCC8	1296	Q09428
NAERIAKQMMENAEW	PIK3R4	956	Q99570
LWMDEVNLQMDAQER	SPTBN2	1921	O15020
LLRDMKDGMDNNHNW	SUN3	136	Q8TAQ9
DWLQADMRDVDMYIN	SLC12A2	891	P55011
AMAAANAQLHWKRME	TMEM104	66	Q8NE00
LDLVDENMWLSNNMY	TRAPPC2	46	P0DI81
DEWQMRFDCAQMENE	MYO18B	1516	Q8IUG5
EQENLMDAEERLTWM	MYH16	86	Q9H6N6
ALSQRALHWNMMLEN	ZNF852	26	Q6ZMS4
ALHWNMMLENDRSMA	ZNF852	31	Q6ZMS4
LDSAQRNLYWDVMME	ZNF529	56	Q6P280
SLMEWRNMIGQDDRN	VWA8	1521	A3KMH1
LDLVDENMWLSNNMY	TRAPPC2B	46	P0DI82
MNSQLEQREGAWMLE	ZNF79	86	Q15937
AMSMLNRAQERIDAW	SON	2246	P18583
EFTQEEWMMLDSAQR	ZNF891	51	A8MT65
GDTNERAMRMADFWL	MRPL17	66	Q9NRX2
LMDWSDMNSNLDLLA	LMF1	116	Q96S06