Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST1 NDST4

2.90e-0441402GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST1 NDST4

2.90e-0441402GO:0050119
GeneOntologyMolecularFunctiondeaminase binding

HNRNPCL1 HNRNPCL3

2.90e-0441402GO:1990827
GeneOntologyBiologicalProcessestablishment of planar polarity

FAT4 FZD3 PKHD1 CPLANE1 FZD2

1.14e-05441395GO:0001736
GeneOntologyBiologicalProcessestablishment of tissue polarity

FAT4 FZD3 PKHD1 CPLANE1 FZD2

1.27e-05451395GO:0007164
GeneOntologyBiologicalProcesssulfur oxidation

MICAL1 MICAL2

4.51e-0521392GO:0019417
GeneOntologyCellularComponentactin cytoskeleton

MICAL1 XIRP1 HNRNPCL1 ARSJ RGS22 DYRK1A ADAM8 HNRNPCL3 JUP MICAL2 CORIN BAIAP2 MLPH TNS3

3.63e-0557614114GO:0015629
GeneOntologyCellularComponentnuclear protein-containing complex

CDK8 NRIP1 HNRNPCL1 SETD1B RB1 C9orf78 POLR2B INTS1 PCGF3 SAGE2P JMJD1C GATAD2B HNRNPCL3 ORC4 PHC3 JUP GTF2H2 ASXL3 PABPC3 TLE4 SAGE1 SMAD3

1.37e-04137714122GO:0140513
GeneOntologyCellularComponentintegrator complex

INTS1 SAGE2P SAGE1

3.65e-04211413GO:0032039
MousePhenokidney cyst

NDST1 FAT4 QRICH1 RND3 BMP7 SLIT3 PKHD1 FLCN CPLANE1

1.63e-051771169MP:0003675
MousePhenodecreased spongiotrophoblast size

PTP4A2 JUP C3 BAIAP2

1.97e-05201164MP:0012099
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FOXK2 HIVEP1 ZNF146 CENPC RB1 C9orf78 INTS1 CHD9 JMJD1C GATAD2B HIRA ORC4 FBXO38 PHC3 EHMT1 KPNA2

4.46e-096081421636089195
Pubmed

Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.

HNRNPCL1 DOCK9 ITGB4 GRSF1 HNRNPCL3 BMP6 PABPC3 GFM1 MLPH ZMYM6

1.24e-07259142109811942
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SEL1L FOXK2 ZNF146 AFTPH PKP4 POLR2B PHRF1 INTS1 DYRK1A ZNF318 ARHGEF11 GRSF1 GATAD2B HIRA EFR3A SLC25A3 ORC4 PHC3 EHMT1 BAIAP2 SPATS2 AGAP1

1.93e-0714971422231527615
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NDST1 SEMA4B PDE4A FOXK2 ARSJ SETD1B DOCK9 INTS1 DYRK1A ARHGEF11 GBA2 ITGB4 HIRA CELSR2 KLHL36 ENTPD2 EHMT1 FLCN

6.49e-0711051421835748872
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDK8 NRIP1 DNAJC13 FOXK2 FRMPD2 CHD9 GRIK2 IDE PCGF3 JMJD1C TTC19 PACS1 GTF2H2 MICAL2 EHMT1 PLCB4 BAIAP2 SPATS2 MLPH CAP2 AGAP1

7.34e-0714891422128611215
Pubmed

Regulation of ovarian function by the TGF-beta superfamily and follistatin.

GDF9 BMP6 BMP7

1.32e-066142312887271
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE4A DNAJC13 PKP4 DYRK1A GRIK2 ZNF318 ARMCX4 ARHGEF11 GATAD2B HIRA CELSR2 PABPC3 EHMT1 BAIAP2 SPATS2 CAP2

2.21e-069631421628671696
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

DOCK9 PKP4 GPRIN3 ITGA4 EFR3A SLC25A3 PACS1 TAOK3 DAAM2 AGAP1

3.72e-063771421038117590
Pubmed

The protein interaction landscape of the human CMGC kinase group.

CDK8 HNRNPCL1 ZNF146 MARCHF10 RB1 POLR2B DYRK1A JUP GTF2H2 TLE4 BAIAP2 SPATS2 KPNA2

5.96e-066951421323602568
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NRIP1 FOXK2 HIVEP1 RB1 DYRK1A IDE JMJD1C GATAD2B PHC3 ZNF518B

5.98e-063981421035016035
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

FOXK2 HIVEP1 SETD1B RB1 DYRK1A PCGF3 GATAD2B FBXO38 PHC3 EHMT1 ZNF518B

6.49e-064951421127705803
Pubmed

Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.

DOCK9 DYRK1A ITGB4 SLC25A3 SMAD3

7.17e-0665142518729074
Pubmed

Human serum complement C3 and factor H in the syndrome of hemolysis, elevated liver enzymes, and low platelet count.

CFH C3

1.66e-052142219703145
Pubmed

The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity.

CFH C3

1.66e-052142219549636
Pubmed

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.

RB1 DYRK1A

1.66e-052142227056896
Pubmed

Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II).

CFH C3

1.66e-052142216612335
Pubmed

The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b.

CFH C3

1.66e-052142219112495
Pubmed

Noncoding variant in the complement factor H gene and risk of exudative age-related macular degeneration in a Chinese population.

CFH C3

1.66e-052142219850835
Pubmed

Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.

BMP6 BMP7

1.66e-052142221898381
Pubmed

Retinoblastoma protein co-purifies with proteasomal insulin-degrading enzyme: implications for cell proliferation control.

RB1 IDE

1.66e-052142220362553
Pubmed

Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification.

CFH C3

1.66e-052142230139996
Pubmed

Polymorphisms in complement component 3 (C3F) and complement factor H (Y402H) increase the risk of postoperative neurocognitive dysfunction following carotid endarterectomy.

CFH C3

1.66e-052142220841369
Pubmed

The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome.

CFH C3

1.66e-052142219454698
Pubmed

Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex.

CFH C3

1.66e-052142225628052
Pubmed

Complement 3 and factor h in human cerebrospinal fluid in Parkinson's disease, Alzheimer's disease, and multiple-system atrophy.

CFH C3

1.66e-052142221435440
Pubmed

Multimeric interactions between complement factor H and its C3d ligand provide new insight on complement regulation.

CFH C3

1.66e-052142219505474
Pubmed

Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha.

RB1 KPNA2

1.66e-052142212695505
Pubmed

Alpha4beta1 integrin acts as a cell receptor for murine polyomavirus at the postattachment level.

ITGA4 ITGB4

1.66e-052142212634351
Pubmed

Zinc-induced self-association of complement C3b and Factor H: implications for inflammation and age-related macular degeneration.

CFH C3

1.66e-052142223661701
Pubmed

Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis.

PKP4 FLCN

1.66e-052142222965878
Pubmed

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.

CFH C3

1.66e-052142219503104
Pubmed

Oocyte-expressed TGF-beta superfamily members in female fertility.

GDF9 BMP6

1.66e-052142210687846
Pubmed

Cdk8 and Hira mutations trigger X chromosome elimination in naive female hybrid mouse embryonic stem cells.

CDK8 HIRA

1.66e-052142239390295
Pubmed

Murine osteogenic protein (OP-1): high levels of mRNA in kidney.

BMP6 BMP7

1.66e-05214221715687
Pubmed

Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d.

CFH C3

1.66e-052142220378178
Pubmed

Differential regulation of actin microfilaments by human MICAL proteins.

MICAL1 MICAL2

1.66e-052142222331357
Pubmed

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.

PKP4 FLCN

1.66e-052142223139756
Pubmed

Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3.

RND3 JUP

1.66e-052142222454524
Pubmed

Structural basis for engagement by complement factor H of C3b on a self surface.

CFH C3

1.66e-052142221317894
Pubmed

Systemic complement activation in age-related macular degeneration.

CFH C3

1.66e-052142218596911
Pubmed

Interaction between gonadotropin-releasing hormone and bone morphogenetic protein-6 and -7 signaling in LβT2 gonadotrope cells.

BMP6 BMP7

1.66e-052142221846488
Pubmed

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.

BMP6 BMP7 SMAD3

1.85e-0513142318329379
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DNAJC13 HIVEP1 AFTPH C9orf78 PHRF1 ZNF318 GATAD2B FBXO38 PACS1 PHC3 LATS1 TLE4 KLHDC4

1.86e-057741421315302935
Pubmed

Regulation of the ovarian reserve by members of the transforming growth factor beta family.

GDF9 BMP6 BMP7

2.35e-0514142322847922
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DNAJC13 CENPC PKP4 POLR2B GPRIN3 IDE PTPRU EFR3A FBXO38 PTP4A2 PACS1 BAIAP2 CAP2 TNS3 KPNA2

2.72e-0510491421527880917
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

FOXK2 RB1 POLR2B INTS1 DYRK1A GATAD2B SLC25A3 JUP EHMT1 SMAD3 KPNA2

2.95e-055831421129844126
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

POLR2B INTS1 GATAD2B HIRA EHMT1 KPNA2

3.16e-05146142623892456
Pubmed

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.

BMP7 TLE4 SLIT3 CORIN

3.48e-0545142422696295
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FOXK2 DOCK9 POLR2B DYRK1A ZNF318 ITGB4 GRSF1 ORC4 PACS1 PHC3 JUP TAOK3 GBP4 TLE4 CPLANE1

3.96e-0510841421511544199
Pubmed

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

NRIP1 STAB2 RND3 MICAL2 CAP2

4.33e-0594142523431145
Pubmed

BMP4 substitutes for loss of BMP7 during kidney development.

BMP6 BMP7

4.95e-053142216154126
Pubmed

Regulation of C3 deposition on gp120 coated CD4 positive cells by decay accelerating factor and factor H.

CFH C3

4.95e-05314227535292
Pubmed

Ultrastructures and interactions of complement factors H and I.

CFH C3

4.95e-05314221401896
Pubmed

Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a chinese population.

CFH C3

4.95e-053142219899988
Pubmed

Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.

CFH C3

4.95e-053142219048105
Pubmed

Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF-9/MAPK/Smad pathway.

GDF9 SMAD3

4.95e-053142228346732
Pubmed

Mitochondrial DNA variants mediate energy production and expression levels for CFH, C3 and EFEMP1 genes: implications for age-related macular degeneration.

CFH C3

4.95e-053142223365660
Pubmed

Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H.

CFH C3

4.95e-053142219680263
Pubmed

Association of genetic variants rs641153 (CFB), rs2230199 (C3), and rs1410996 (CFH) with age-related macular degeneration in a Brazilian population.

CFH C3

4.95e-053142234233521
Pubmed

Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.

BMP7 SMAD3

4.95e-053142220093492
Pubmed

Genetic control of the alternative pathway of complement in humans and age-related macular degeneration.

CFH C3

4.95e-053142219825847
Pubmed

Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.

CFH C3

4.95e-053142228671664
Pubmed

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD.

CFH C3

4.95e-053142219823576
Pubmed

A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7.

BMP6 BMP7

4.95e-05314221427904
Pubmed

Variation in complement factor 3 is associated with risk of age-related macular degeneration.

CFH C3

4.95e-053142217767156
Pubmed

Effect of Risk Alleles in CFH, C3, and VEGFA on the Response to Intravitreal Bevacizumab in Tunisian Patients with Neovascular Age-related Macular Degeneration.

CFH C3

4.95e-053142227116510
Pubmed

Bone morphogenetic protein-2, -6, and -7 differently regulate osteogenic differentiation of human periodontal ligament stem cells.

BMP6 BMP7

4.95e-053142223853066
Pubmed

Inherited Kidney Complement Diseases.

CFH C3

4.95e-053142233536243
Pubmed

C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa.

PDE6B C3

4.95e-053142231209071
Pubmed

Interaction of uromodulin and complement factor H enhances C3b inactivation.

CFH C3

4.95e-053142227113631
Pubmed

Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation.

F8 C3

4.95e-053142232582142
Pubmed

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8.

CDK8 RB1

4.95e-053142218794899
Pubmed

Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration.

CFH C3

4.95e-053142223747511
Pubmed

Growth Differentiation Factor-9 Promotes Fibroblast Proliferation and Migration in Keloids through the Smad2/3 Pathway.

GDF9 SMAD3

4.95e-053142227855376
Pubmed

Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique.

BMP6 BMP7

4.95e-053142235033126
Pubmed

Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines.

BMP6 BMP7

4.95e-053142218349123
Pubmed

Complement component C3 and risk of age-related macular degeneration.

CFH C3

4.95e-053142219168221
Pubmed

The association of polypoidal choroidal vasculopathy clinical phenotypes with previously reported genetic markers.

CFH C3

4.95e-053142232328755
Pubmed

R102G polymorphism of the C3 gene associated with exudative age-related macular degeneration in a French population.

CFH C3

4.95e-053142220664795
Pubmed

Comparison of surface recognition and C3b binding properties of mouse and human complement factor H.

CFH C3

4.95e-053142216023208
Pubmed

Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials.

CFH C3

4.95e-053142227099955
Pubmed

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

BMP6 BMP7

4.95e-05314222263636
Pubmed

Genetic architecture of human thinness compared to severe obesity.

PKHD1 PRDM6

4.95e-053142230677029
Pubmed

Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci.

RB1 HIRA

4.95e-053142217242198
Pubmed

The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity.

STAB2 F8

4.95e-053142230124466
Pubmed

Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).

CFH C3

4.95e-05314229988761
Pubmed

Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk.

CFH C3

4.95e-053142221555552
Pubmed

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.

CFH C3

4.95e-053142236643920
Pubmed

Bone morphogenetic proteins 4, 6, and 7 are up-regulated in mouse spinal cord during experimental autoimmune encephalomyelitis.

BMP6 BMP7

4.95e-053142217722066
Pubmed

Genotype-phenotype correlations of low-frequency variants in the complement system in renal disease and age-related macular degeneration.

CFH C3

4.95e-053142229888403
Pubmed

Disruption of the alternative pathway convertase occurs at the staphylococcal surface via the acquisition of factor H by Staphylococcus aureus.

CFH C3

4.95e-053142221163532
Pubmed

Growth differentiation factor 3 is induced by bone morphogenetic protein 6 (BMP-6) and BMP-7 and increases luteinizing hormone receptor messenger RNA expression in human granulosa cells.

BMP6 BMP7

4.95e-053142222305102
Pubmed

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.

CFH C3

4.95e-053142221402993
Pubmed

Interactions between human complement components factor H, factor I and C3b.

CFH C3

4.95e-05314229291131
Pubmed

Synergistic effects of BMP-2, BMP-6 or BMP-7 with human plasma fibronectin onto hydroxyapatite coatings: A comparative study.

BMP6 BMP7

4.95e-053142228434979
Pubmed

Susceptibility genes and progression in age-related maculopathy: a study of single eyes.

CFH C3

4.95e-053142219797206
Pubmed

Joint association of complement component 3 and CC-cytokine ligand2 (CCL2) or complement component 3 and CFH polymorphisms in age-related macular degeneration.

CFH C3

4.95e-053142228095095
Pubmed

Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome.

CFH C3

4.95e-053142223356914
Pubmed

Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration.

CFH C3

4.95e-053142230253188
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXK2 RB1 DYRK1A QRICH1 JMJD1C GATAD2B HIRA TTLL7 ORC4 TLE4 PRDM6 SMAD3 KPNA2

5.30e-058571421325609649
InteractionH3C3 interactions

FOXK2 HIVEP1 ZNF146 CENPC RB1 C9orf78 ITGA4 JMJD1C GATAD2B HIRA ORC4 FBXO38 PHC3 EHMT1 KPNA2

1.58e-0649513815int:H3C3
InteractionDCANP1 interactions

FAT4 FZD3 IDE CELSR2

7.53e-06191384int:DCANP1
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PKP4 ARMCX4 JUP KPNA2

8.86e-0543994409
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1B EHMT1 PRDM6

8.42e-0434993487
GeneFamilyBone morphogenetic proteins|Astacins

BMP6 BMP7

1.58e-0311992455
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD3 FZD2

1.58e-0311992286
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDK8 NRIP1 DNAJC13 FOXK2 HIVEP1 CENPC RB1 DOCK9 PKP4 POLR2B DYRK1A CHD9 SPG11 HIRA EFR3A TDRD7 TAOK3 MICAL2 TLE4 PLCB4 OSMR CAP2 SMAD3 AGAP1

2.79e-1185614024M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CDK8 NRIP1 DNAJC13 FOXK2 HIVEP1 RB1 PKP4 DYRK1A CHD9 HIRA TDRD7 TLE4 CAP2 SMAD3 AGAP1

3.22e-0846614015M13522
CoexpressionGENTILE_UV_HIGH_DOSE_DN

CDK8 NRIP1 ZNF146 PKP4 DYRK1A PCGF3 RND3 TLE4 FZD2 SMAD3 KPNA2

4.66e-0728914011M13630
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

NRIP1 ZNF146 CENPC DOCK9 DYRK1A CHD9 ZNF318 MICAL2 TLE4 SMAD3

5.14e-0630014010M8702
CoexpressionDAZARD_UV_RESPONSE_CLUSTER_G6

ZNF146 CENPC DOCK9 CHD9 MICAL2 TLE4 SMAD3

1.33e-051451407M1810
CoexpressionGENTILE_UV_RESPONSE_CLUSTER_D6

ZNF146 TLE4 FZD2 SMAD3

3.59e-05351404M15187
CoexpressionGSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP

CHD9 MUC13 ARMCX4 ITGA4 ITGB4 GBP4 PLCB4

4.31e-051741407M6877
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN

NRIP1 HNRNPCL1 CHD9 HNRNPCL3

4.49e-05371404MM570
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

CFH NRIP1 DNAJC13 ARSJ PKP4 FRMPD2 CHD9 ITGA4 JMJD1C BMP6 ASXL3 SLIT3 PKHD1 C3 EGFLAM CPLANE1 CRISPLD1 AGAP1

5.42e-0679914018gudmap_developingGonad_e18.5_epididymis_1000
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 ITGB4 F8 MICAL2 CORIN OSMR MLPH CRISPLD1

1.13e-07180141867c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 ARMCX4 ITGB4 TTLL7 MICAL2 ECSCR PLCB4 OSMR

1.58e-071881418405efea75233ecf70f7d19b630230798d817b7f2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA4B CLSTN1 ITGB4 RND3 BMP7 JUP SH3RF2 SMAD3

2.34e-071981418fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH FAT4 NDST4 GRIK2 IL1RAPL1 RND3 BMP7 PRDM6

2.53e-072001418fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellfacs|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ZNF146 CHD9 CLSTN1 TTC19 PTP4A2 BMP6

1.30e-061721417a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6 CAP2

1.46e-061751417d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6 CAP2

1.46e-061751417454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

NDST4 HPSE2 ERI2 SYDE1 RND3 PRDM6 CAP2

1.51e-061761417852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

NDST4 HPSE2 ERI2 SYDE1 RND3 PRDM6 CAP2

1.51e-061761417d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 GRIK2 ITGB4 TTLL7 PLCB4 SPATS2 MLPH

1.69e-061791417a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ARSJ EXTL1 TLE4 SLIT3 PLCB4 CRISPLD1

1.76e-061801417e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ ITGB4 F8 MICAL2 OSMR MLPH CRISPLD1

1.89e-061821417ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ARSJ EXTL1 TLE4 SLIT3 PLCB4 CRISPLD1

1.89e-06182141772e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH ARSJ EXTL1 TLE4 SLIT3 PLCB4 CRISPLD1

1.89e-06182141705c167158815bf25d509df59ab386e1990712765
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ ITGB4 F8 MICAL2 OSMR MLPH CRISPLD1

1.89e-06182141747ff6b4002a4167412c79210651316d1342503f9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 SPATA6L F8 JUP MICAL2 ECSCR BAIAP2

1.96e-061831417a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 SPATA6L F8 JUP MICAL2 ECSCR BAIAP2

1.96e-06183141713ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT4 CTSF ARSJ GRIK2 MICAL2 PLCB4 SEC14L2

1.96e-061831417351d575339038bd4a66f408da518c567444208e8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 DOCK9 ITGB4 BMP6 SH3RF2 ENTPD2 PLCB4

2.11e-061851417a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PLCB4 PRDM6

2.34e-061881417b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPRIN3 HPSE2 PIWIL2 EXTL1 TTLL7 SLIT3 DAAM2

2.43e-061891417032f169e8ede653117919bf97c17f92043320b3c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPRIN3 HPSE2 PIWIL2 EXTL1 TTLL7 SLIT3 DAAM2

2.43e-06189141707208d32afca6f93207a2ac35b647b31a9f71b7c
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH SLC22A6 BMP7 EGFLAM FZD2 PRDM6

2.68e-06123141664a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MEPE ENTPD2 SLIT3 DAAM2 EGFLAM FZD2 CRISPLD1

3.19e-0619714172cb1f557ce1400398975de94638126b4522567f3
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

CFH PKP4 ITGB4 PACS1 SH3RF2 SLIT3 PLCB4

3.53e-062001417682960e28542a3d6c119047cd0131941932cfdea
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK9 ITGA4 JUP TLE4 EGFLAM PLCB4 ZNF518B

3.53e-062001417e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH EXTL1 BMP6 DAAM2 EGFLAM PLCB4 CRISPLD1

3.53e-062001417b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK9 ITGA4 JUP TLE4 EGFLAM PLCB4 ZNF518B

3.53e-0620014173372c488a39fe812fa94e4f0564594186fea3db5
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH EXTL1 BMP6 DAAM2 EGFLAM PLCB4 CRISPLD1

3.53e-0620014177c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRIP1 INTS1 F8 ASXL3 PABPC3 TLE4

8.73e-061511416f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

CFH HPSE2 GRSF1 IL1RAPL1 EGFLAM PRDM6

1.13e-051581416410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPRIN3 HPSE2 TTLL7 SLIT3 DAAM2 EGFLAM

1.30e-051621416c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPRIN3 HPSE2 TTLL7 SLIT3 DAAM2 EGFLAM

1.30e-051621416f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPRIN3 HPSE2 TTLL7 SLIT3 DAAM2 EGFLAM

1.30e-0516214165d902bb31e691aea9749617cc88303c2448f24b8
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH SLC22A6 BMP6 BMP7 EGFLAM FZD2

1.60e-0516814169930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 GRIK2 MICAL2 SLIT3 DAAM2 CAP2

1.71e-05170141699dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 GRIK2 MICAL2 SLIT3 DAAM2 CAP2

1.71e-0517014163a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 GRIK2 MICAL2 SLIT3 DAAM2 CAP2

1.71e-051701416cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH SLC22A6 BMP6 BMP7 EGFLAM FZD2

1.77e-0517114162e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH SLC22A6 BMP6 BMP7 EGFLAM FZD2

1.77e-051711416e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HIVEP1 ARSJ PTPRU TLE4 PLCB4 CRISPLD1

1.95e-05174141699eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

EXTL1 TECRL MUC13 ITGA4 IL1RAPL1 GTF2H2

2.02e-0517514162812ac2ef41d245db544697fb6da1883361c96e8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA4 SH3RF2 SLIT3 BAIAP2 KIAA2012 SMAD3

2.29e-0517914169ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFH MARCHF10 EXTL1 BMP6 GBP4 SH3RF2

2.29e-0517914168c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC22A6 BMP6 BMP7 GBP4 PRDM6

2.32e-0510714154a18261492371d19b8dbd403e197fdf64ef69392
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

XIRP1 ITGA4 ENTPD2 EGFLAM PRDM6 CAP2

2.36e-05180141638035cf2c6fbc443ea10ca7e942572715ed572da
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 STAB2 F8 ECSCR DAAM2 OSMR

2.44e-0518114164df7972f88117108698efd06b124b232f8588981
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARMCX4 ITGB4 MICAL2 OSMR MLPH CRISPLD1

2.44e-0518114164ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 STAB2 F8 ECSCR DAAM2 OSMR

2.44e-051811416cbb530566893281289026bfd93adf721decd4ca3
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

CFH PTPRU ITGB4 JUP ASXL3 OSMR

2.52e-051821416caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH SYDE1 GBP4 ECSCR SAGE1 OSMR

2.59e-0518314166cdadb3ece45a94a2915063aa461048e1d371ccd
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH XIRP1 SLIT3 CORIN DAAM2 CAP2

2.59e-0518314168de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH SYDE1 GBP4 ECSCR SAGE1 OSMR

2.59e-0518314168714d3e7663c93cdf9b25b647353572e136f30c3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFH SYDE1 GBP4 ECSCR SAGE1 OSMR

2.59e-051831416c7fc96ac1d5d31ccefe0c1fc6ec76c7d8607a172
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA4 SH3RF2 SLIT3 BAIAP2 KIAA2012 SMAD3

2.59e-0518314161645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TTLL7 MICAL2 SLIT3 DAAM2 PLCB4 PRDM6

2.59e-051831416667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK9 PKP4 F8 BMP6 PLCB4 OSMR

2.59e-051831416ff95382cfed592190d0636d2b750328471f82e0d
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIWIL2 ARMCX4 ERI2 BMP7 BAIAP2 SMAD3

2.67e-051841416b998803180322a5ea2b567928dea531c26816c3c
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ DOCK9 GRIK2 ITGB4 PLCB4 OSMR

2.67e-051841416f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARSJ DOCK9 GRIK2 ITGB4 PLCB4 OSMR

2.67e-0518414168bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH PDE4A SPATA6L ENTPD2 ANKDD1B PRDM6

2.67e-051841416d754c3de621429b220ae4ac426cdfc619e848462
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH GRIK2 EXTL1 DAAM2 PLCB4 CRISPLD1

2.76e-0518514168ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ITGB4 TTLL7 ECSCR OSMR CRISPLD1

2.76e-051851416f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellfacs-Heart-RV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 BMP6 JUP GBP4 ECSCR

2.76e-0518514167cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 IL1RAPL1 DAAM2 CRISPLD1 PRDM6 SMAD3

2.76e-0518514163b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH GRIK2 EXTL1 DAAM2 PLCB4 CRISPLD1

2.76e-051851416b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 ITGB4 MICAL2 ZNF518B OSMR CRISPLD1

2.84e-051861416c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HPSE2 ITGB4 BMP7 ENTPD2 DAAM2 TNS3

2.93e-051871416dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Tumor_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

FAT4 DOCK9 SYDE1 ECSCR ASXL3 PLCB4

2.93e-0518714162713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HPSE2 ITGB4 BMP7 ENTPD2 DAAM2 TNS3

2.93e-051871416ae90c263f80c36a410150d499e268d198944a3d9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA4 IL1RAPL1 MICAL2 SLIT3 DAAM2 PLCB4

2.93e-051871416ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK9 ARMCX4 ITGB4 MICAL2 ECSCR OSMR

2.93e-05187141612129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

FAT4 DOCK9 ITGB4 F8 BMP6 PLCB4

2.93e-05187141640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK9 ARMCX4 ITGB4 MICAL2 ECSCR OSMR

2.93e-05187141683930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA4 IL1RAPL1 MICAL2 SLIT3 DAAM2 PLCB4

2.93e-051871416530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

CFH FAT4 HPSE2 SLIT3 DAAM2 PRDM6

2.93e-051871416bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 STAB2 F8 TTLL7 ECSCR OSMR

3.02e-0518814160aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 TDRD7 LATS1 PLCB4 PRDM6 SMAD3

3.02e-0518814166468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 TDRD7 LATS1 PLCB4 PRDM6 SMAD3

3.02e-0518814167a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 TDRD7 LATS1 PLCB4 PRDM6 SMAD3

3.02e-0518814169cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 GRIK2 DAAM2 OSMR PRDM6 CAP2

3.02e-051881416d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

CFH GRIK2 EXTL1 DAAM2 PLCB4 CRISPLD1

3.02e-0518814167b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TTLL7 BMP6 BMP7 TLE4 SLIT3 AGAP1

3.02e-051881416b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6

3.11e-0518914167fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6

3.11e-05189141606b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellfacs-Heart-LV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 JUP GBP4 ECSCR PLCB4

3.11e-051891416d424d2554595b2304219f7324406b401711af7c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6

3.11e-051891416127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 TTLL7 MICAL2 SLIT3 DAAM2 PRDM6

3.11e-0518914162cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 JUP GBP4 ECSCR PLCB4

3.11e-051891416393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCellfacs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 JUP GBP4 ECSCR PLCB4

3.11e-051891416bec57459ad4bab15b2532b57722549fec2e771fb
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RGS22 HPSE2 SLIT3 DAAM2 PRDM6 SMAD3

3.11e-05189141645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK9 ITGB4 F8 BMP6 SH3RF2 PLCB4

3.20e-051901416bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 F8 TTLL7 ECSCR PLCB4 OSMR

3.20e-051901416a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HPSE2 ITGB4 BMP7 ENTPD2 DAAM2 TNS3

3.20e-0519014163a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 BMP6 JUP ECSCR PLCB4

3.20e-05190141689d1d686cc683206534e2157554d7d0df5d53497
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

CFH FAT4 DOCK9 F8 BMP6 PLCB4

3.20e-0519014161519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 PKP4 BMP6 JUP ECSCR PLCB4

3.20e-05190141665ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 F8 TTLL7 ECSCR PLCB4 OSMR

3.20e-05190141625525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CHD9 ITGA4 JMJD1C JUP GBP4 TLE4

3.20e-051901416f623f0bdece6002b68ac2207e99408b24a2b1194
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK9 PKP4 BMP6 PLCB4 OSMR MLPH

3.20e-05190141678e7c502b0450c0b37652b1896a2a752fd8a2111
DrugDNA-PK Inhibitor III; Up 200; 1uM; PC3; HT_HG-U133A

PDE4A ZNF318 PTPRU ADAM8 ITGB4 KLHL22 BMP7 CELSR2 BAIAP2 OSMR

4.07e-07200138107518_UP
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

NRIP1 HIVEP1 DOCK9 DYRK1A CHD9 JMJD1C TAOK3 TLE4 TNS3

1.19e-0617413897530_DN
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; PC3; HT_HG-U133A

NDST1 VPS33A PCGF3 ADAM8 SYDE1 HIRA KLHL22 JUP SMAD3

3.18e-0619613897142_DN
DrugKS24

GRSF1 PABPC3 SAGE1

4.30e-0661383CID000099135
DrugRaloxifene Hydrochloride

SEMA4B RB1 DOCK9 POLR2B CLSTN1 GDF9 F8 RND3 BMP7 TAOK3 CLCN6 MICAL2 ENTPD2 C3 CAP2 TNS3 KPNA2

1.76e-0585713817ctd:D020849
DrugTrimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A

SEL1L CTSF RB1 PACS1 BMP7 CLCN6 C3 OSMR

2.57e-0519513883478_UP
DrugMesoridazine besylate [32672-69-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A

MICAL1 RB1 INTS1 PTPRU ITGB4 KLHL22 C3 SMAD3

2.67e-0519613882874_DN
DrugFluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

HIVEP1 PDE6B ARHGEF11 KLHL22 PACS1 CLCN6 BAIAP2 OSMR

2.67e-0519613883314_UP
DrugNalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; PC3; HT_HG-U133A

SEL1L PKP4 ARHGEF11 TTLL7 PACS1 BMP6 CELSR2 KLHL36

2.67e-0519613882063_UP
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

SEL1L PDE4A PKP4 VPS33A DYRK1A PCGF3 CELSR2 CAP2

2.67e-0519613882687_DN
DrugLithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A

NDST1 DOCK9 PTPRU HIRA KLHL22 BMP7 FLCN C3

2.67e-0519613883816_DN
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A_EA

NDST1 DOCK9 PTPRU ITGB4 HIRA KLHL22 KLHL36 SPATS2

2.77e-0519713881071_UP
DrugHarmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A

MICAL1 DYRK1A ITGB4 PACS1 MICAL2 FLCN BAIAP2 OSMR

2.77e-0519713885495_UP
DrugXylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A

CFH PDE6B SYDE1 HIRA KLHL22 CLCN6 OSMR CPLANE1

2.77e-0519713884066_DN
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A

NDST1 PDE4A HIRA KLHL22 PHC3 TLE4 SEC14L2 SMAD3

2.77e-0519713884732_DN
DrugThioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; HL60; HG-U133A

ZNF146 RB1 CHD9 ITGA4 F8 HIRA EFR3A FLCN

2.98e-0519913881390_UP
Drugoctestrol

FLCN SAGE1

3.65e-0521382CID000006827
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST1 PKP4 DYRK1A NDST4 CHD9 TAOK3 SH3RF2

6.37e-061521347DOID:0060041 (implicated_via_orthology)
Diseasecomplement C3B measurement

CFH C3

2.05e-0521342EFO_0020275
Diseaseintellectual disability (implicated_via_orthology)

NDST1 RB1 DYRK1A NDST4 GATAD2B

2.40e-05751345DOID:1059 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_implicated_in)

DYRK1A ITGA4 BAIAP2

4.91e-05161343DOID:0060041 (is_implicated_in)
Diseasecomplement C3D fragment measurement

CFH C3

6.12e-0531342EFO_0020277
Diseasecomplement C3 measurement

CFH C3

6.12e-0531342EFO_0004983
Diseaseneuroticism measurement

HIVEP1 MARCHF10 PKP4 DYRK1A HPSE2 QRICH1 IL1RAPL1 ORC4 TAOK3 MICAL2 ASXL3 PKHD1 BAIAP2 SPATS2

7.01e-0590913414EFO_0007660
Diseasev-set and transmembrane domain-containing protein 4 measurement

CFH C3

3.03e-0461342EFO_0803247
Diseaseresponse to allopurinol, uric acid measurement

BAIAP2 OR4D5 ZMYM6

4.12e-04321343EFO_0004761, EFO_0006337
Diseasevascular cell adhesion protein 1 measurement

CFH ITGA4

4.24e-0471342EFO_0020846
Diseasebifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 measurement

CFH NDST1

4.24e-0471342EFO_0802332
Diseaseregulator of G-protein signaling 8 measurement

CFH C3

4.24e-0471342EFO_0801997
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

GBA2 CORIN

4.24e-0471342EFO_0800551
Diseaseglycosyl-N-behenoyl-sphingadienine (d18:2/22:0) measurement

GBA2 CORIN

4.24e-0471342EFO_0800520
Diseasealpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 measurement

CFH C3

5.63e-0481342EFO_0801373
Diseasecalcium/calmodulin-dependent protein kinase type 1D measurement

CFH C3

5.63e-0481342EFO_0008063
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

CFH C3

5.63e-0481342DOID:0080301 (is_implicated_in)
DiseaseAtypical hemolytic-uremic syndrome

CFH C3

7.22e-0491342cv:C2931788
Diseasecellular retinoic acid-binding protein 1 measurement

CFH C3

7.22e-0491342EFO_0801463
Diseasetumor necrosis factor ligand superfamily member 14 measurement

CFH C3

7.22e-0491342EFO_0010613
Disease22q11 partial monosomy syndrome

JMJD1C HIRA

7.22e-0491342C3266101
DiseaseC3 glomerulopathy

CFH C3

7.22e-0491342C4087273
DiseaseHemolytic-uremic syndrome

CFH C3

7.22e-0491342cv:C0019061
DiseaseRNA-binding protein 24 measurement

CFH C3

7.22e-0491342EFO_0802030
Diseaseceramide measurement

ARSJ GBA2 CELSR2 MICAL2 CORIN SEC14L2

7.36e-042351346EFO_0010222
DiseaseDNA-directed RNA polymerases I and III subunit RPAC1 measurement

CFH C3

8.99e-04101342EFO_0801535
DiseaseAtypical Hemolytic Uremic Syndrome

CFH C3

8.99e-04101342C2931788
Diseasebone morphogenetic protein 7 measurement

CFH BMP6

8.99e-04101342EFO_0020187
DiseaseOCIA domain-containing protein 1 measurement

CFH C3

8.99e-04101342EFO_0008252
DiseaseMarfan syndrome (implicated_via_orthology)

BMP6 BMP7

8.99e-04101342DOID:14323 (implicated_via_orthology)
DiseaseAsymmetric crying face association

JMJD1C HIRA

8.99e-04101342C0431406
DiseaseC-C motif chemokine 21 measurement

UBA5 DNAJC13

8.99e-04101342EFO_0008048
Diseasepneumonia (implicated_via_orthology)

ITGA4 C3

8.99e-04101342DOID:552 (implicated_via_orthology)
Disease22q11 Deletion Syndrome

JMJD1C HIRA

8.99e-04101342C2936346
Diseasegastrin-releasing peptide measurement

CFH JMJD1C

1.10e-03111342EFO_0022000
DiseaseAutistic Disorder

PDE4A GRIK2 ITGA4 JMJD1C IL1RAPL1 AGAP1

1.26e-032611346C0004352
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

NDST1 SLIT3

1.31e-03121342DOID:3827 (implicated_via_orthology)
Diseasevascular endothelial growth factor A measurement

CFH JMJD1C

1.31e-03121342EFO_0010804
Diseaseoncostatin-M measurement

CFH C3

1.31e-03121342EFO_0010792
Diseasetyrosine-protein kinase ZAP-70 measurement

CFH C3

1.31e-03121342EFO_0020833
Diseasetriglycerides to total lipids in medium LDL percentage

JMJD1C CELSR2 ANKDD1B

1.54e-03501343EFO_0022334
Diseasetriglycerides to total lipids in large LDL percentage

JMJD1C CELSR2 ANKDD1B

1.63e-03511343EFO_0022331
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

CFH PTPRU

1.80e-03141342DOID:10976 (biomarker_via_orthology)
Diseasewet macular degeneration

CFH C3

1.80e-03141342EFO_0004683
DiseaseC-C motif chemokine 19 measurement

CFH DNAJC13

1.80e-03141342EFO_0008047
Diseaseosteoarthritis (implicated_via_orthology)

BMP7 SMAD3

2.07e-03151342DOID:8398 (implicated_via_orthology)
DiseaseDiGeorge Syndrome

JMJD1C HIRA

2.36e-03161342C0012236
DiseaseShprintzen syndrome

JMJD1C HIRA

2.36e-03161342C0220704
DiseaseCONOTRUNCAL ANOMALY FACE SYNDROME

JMJD1C HIRA

2.36e-03161342C0795907
DiseaseAstrocytosis

ITGA4 ITGB4

2.66e-03171342C3887640
DiseaseAntibody Deficiency Syndrome

CFH C3

2.66e-03171342C0003257
DiseaseGliosis

ITGA4 ITGB4

2.66e-03171342C0017639
Diseaseresponse to bronchodilator, FEV/FEC ratio

CFH RB1 GPRIN3 RFX6 GRIK2 ITGA4 BMP7 TLE4 PKHD1 AGAP1

2.67e-0376613410EFO_0004713, GO_0097366
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

SPG11 JMJD1C CELSR2 ANKDD1B

2.73e-031271344EFO_0008595, EFO_0020947
Diseaserenal cell carcinoma (is_marker_for)

RB1 BMP6 BMP7 JUP

2.81e-031281344DOID:4450 (is_marker_for)
Diseasebipolar disorder, sex interaction measurement

TLE4 SLIT3

2.99e-03181342EFO_0008343, MONDO_0004985
DiseaseAge-related macular degeneration

CFH C3

2.99e-03181342cv:C0242383
Diseaseobesity (implicated_via_orthology)

FAT4 BMP6 BMP7 JUP C3

3.06e-032151345DOID:9970 (implicated_via_orthology)
Diseasecarcinoma (implicated_via_orthology)

FAT4 JUP LATS1

3.12e-03641343DOID:305 (implicated_via_orthology)
Diseasedepressive symptom measurement

HIVEP1 HNRNPCL1 MARCHF10 TAOK3 ASXL3 PKHD1 BAIAP2

3.40e-034261347EFO_0007006
Diseasealpha-tocopherol measurement

DYRK1A SEC14L2

3.69e-03201342EFO_0007898
DiseaseAbdominal Aortic Aneurysm

PKP4 MEPE CELSR2

3.70e-03681343EFO_0004214
Diseasemyeloid white cell count

NRIP1 DNAJC13 SETD1B DYRK1A QRICH1 ITGA4 PCGF3 JMJD1C MICAL2 C3 TNS3

3.72e-0393713411EFO_0007988
DiseaseCOVID-19 (is_implicated_in)

CFH C3

4.06e-03211342DOID:0080600 (is_implicated_in)
Diseasegastric ulcer

JUP JRK

4.06e-03211342EFO_0009454
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

SPG11 JMJD1C CELSR2 ANKDD1B

4.28e-031441344EFO_0004611, EFO_0020943
DiseaseAgents acting on the renin-angiotensin system use measurement

NRIP1 ZNF318 CELSR2 CLCN6 PKHD1 PRDM6

4.36e-033351346EFO_0009931
Diseasewellbeing measurement

FAT4 HIVEP1 MARCHF10 GATAD2B TAOK3 ASXL3 PKHD1 BAIAP2 SMAD3

4.43e-036921349EFO_0007869
Diseaseseminoma (is_marker_for)

RB1 JUP

4.46e-03221342DOID:4440 (is_marker_for)
Diseasenephrosis (biomarker_via_orthology)

CFH PTPRU

4.46e-03221342DOID:2527 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MLQHQFPSVQANAAA

PKP4

536

Q99569
SSTFNRVNANMSHPL

ERI2

506

A8K979
NYQFAVRAMNSHGPS

EGFLAM

211

Q63HQ2
ISLVSFNSRPDGMHQ

AGAP1

456

Q9UPQ3
SPGDFRTNMNVVHQN

AFTPH

151

Q6ULP2
SYTIIQQMPRGNHFT

FAT4

1456

Q6V0I7
SRFQLFMQEAESHPQ

ARHGEF11

851

O15085
NHMGNVTFTIPANRE

C3

81

P01024
NPVSALHQFAQMQRV

ADAD1

96

Q96M93
QIPNSHNMTTTLNYR

CFH

816

P08603
QEMANPQHFLGSSLV

CELSR2

1611

Q9HCU4
AMQHISYLNSRQFPT

CLSTN1

601

O94985
AGQMPHSHQYSDRRQ

DYRK1A

31

Q13627
MGRSNPLFHQAASRV

ADAM8

696

P78325
PLNSYMNATNHAIVQ

BMP7

366

P18075
TFGNMNNAVRPVFAH

EFR3A

246

Q14156
MRAAAQPQAVASTHA

ARMCX4

396

Q5H9R4
TDAGTSHRQQFYQMP

ASXL3

1921

Q9C0F0
SHRQQFYQMPVAARG

ASXL3

1926

Q9C0F0
LQNNHTAADMYLSPV

RB1

596

P06400
QSHPLQYIGHDRTMQ

PCGF3

61

Q3KNV8
NLTHRVYLMNPFSVN

OSMR

326

Q99650
NSLFPAQFMNGNIHI

QRICH1

381

Q2TAL8
INYPESHRLGSMVNQ

RFX6

806

Q8HWS3
HFVHMRGLPFQANAQ

GRSF1

401

Q12849
PSNDSRQMHQALQDF

PADI4

436

Q9UM07
SHRQIHLMNSFGFPQ

ORC4

211

O43929
NLRDNHPLQFMEFSS

DAAM2

26

Q86T65
PHSMNSRVFIGNLNT

HNRNPCL1

11

O60812
MFSSVAHLARANPFN

SLC25A3

1

Q00325
VRYHNNLAAQPVMQT

KLHL36

271

Q8N4N3
RMNTAFTPFLHQRNG

FLCN

221

Q8NFG4
YVPHRQNNSTRNKGM

MEPE

471

Q9NQ76
PNNMQVLYTALQHSS

INTS1

456

Q8N201
VPNRNSHNMELYNIS

LATS1

411

O95835
GQVNNAAASPLHMLA

FOXK2

591

Q01167
PHSMNSRVFIGNLNT

HNRNPCL3

11

B7ZW38
VYFSHNPAGTSVQNM

LIPJ

246

Q5W064
MYTQRVQQILASHNP

ARSJ

241

Q5FYB0
FAPRNSNTMAAAALA

ASPDH

186

A6ND91
HYTRAQANSPRPAMN

JMJD1C

276

Q15652
RAFLLMASQYQQPHE

CAP2

86

P40123
MAQRPQNFNSSARVS

ENTPD2

286

Q9Y5L3
QHTYCNIPMTLINGQ

IL1RAPL1

646

Q9NZN1
QGPHARYNMNDAIFS

JRK

351

O75564
LMHSNSLNNSNIPRF

PDE4A

341

P27815
HRGTNNLYQMKSQNP

PDE6B

601

P35913
MPANHQTFLRQRTFS

FAM214A

981

Q32MH5
AYNQTIMPNLLGHTN

FZD2

51

Q14332
SFRINIPGNMAHSSQ

PHRF1

776

Q9P1Y6
NPISIFMTHLSNYGN

NDST1

521

P52848
ANTEPRANLHMNLYE

KIAA2012

646

Q0VF49
LRSPYNSHMGNNASR

NRIP1

1121

P48552
TSPENMHRNVAQYGL

MICAL1

446

Q8TDZ2
ADHYSQQMAQQLRLP

GBP4

346

Q96PP9
PHSMNSRVFIGNLNT

HNRNPCL4

11

P0DMR1
SNNSLSEMTHFRPQL

F8

846

P00451
IYMNLASHIQPGTVN

GATAD2B

316

Q8WXI9
NPISIFMTHLSNYGN

NDST4

511

Q9H3R1
NEPNNYRTMHGRAVN

HPSE2

261

Q8WWQ2
NNMQRPGFATHAASI

ITGB4

796

P16144
HPEAEMAQNSVRLNY

JUP

466

P14923
MQQPQISVYSGSDRH

PHC3

31

Q8NDX5
GYFMTAVPQTQNHAA

PABPC3

401

Q9H361
MQYVNGAATTHQLPV

PACS1

711

Q6VY07
YLMVNTSQHAPGQRA

PTPRU

71

Q92729
FTQATQLSRHQRMPN

PRDM6

566

Q9NQX0
MSTNENANTPAARLH

KPNA2

1

P52292
TPLRKRYNSHQMGQS

FBXO38

646

Q6PIJ6
NPAASDFHLQAMIQS

CHD9

1166

Q3L8U1
MAHSRTSTPLLQQYQ

CHD9

2006

Q3L8U1
PNTHVSQVFNLFRTM

CLCN6

816

P51797
ASALMYHRNESLQPS

KLHL22

271

Q53GT1
NHFSVRQMLATTSPA

DOCK9

421

Q9BZ29
KSRINIYQRNAPNHM

CPLANE1

1486

Q9H799
NPGMYQHRTVIADQF

GBA2

176

Q9HCG7
YSNSSVRNELPMHHN

CENPC

541

Q03188
NCMQANPHYARVIGT

CRISPLD1

421

Q9H336
FVQMANLSPAHQARS

FRMPD2

656

Q68DX3
PAMDAAGIHLRQFSN

BORA

376

Q6PGQ7
FLLFRGHNSQPTMTQ

ECSCR

16

Q19T08
SFPLNAHMNATNHAI

BMP6

446

P22004
AMISSLSQNHPDNRN

CTSF

146

Q9UBX1
NNLDHPSVFMQTRFV

CORIN

861

Q9Y5Q5
DMFCNSTHPQVRAQT

DNAJC13

1861

O75165
VSHFPNQNDNGSRMA

MARCHF10

606

Q8NA82
NLTFHVINTGNSMAP

ITGA4

806

P13612
MPNLLNHYDQQTAAL

FZD3

46

Q9NPG1
RSGFSVAMAPNHQTL

KLHDC4

296

Q8TBB5
HPSAQNGLFNMTLVS

GDF9

246

O60383
YMRSLNNFRAEQPHQ

IDE

666

P14735
YLVSAHAMNNSGPTA

HIRA

236

P54198
QFPQMTVSSLQCNRH

GRIK2

336

Q13002
RGRQHSVFQSMLQNF

GPRIN3

746

Q6ZVF9
LIMTSDYQRSNPHAA

CDK8

416

P49336
ILMNSSRDNSHPFVG

GFM1

341

Q96RP9
GEMTEVLPNQRYNSH

SEC14L2

331

O76054
MASHNTLQNFTAAIP

SLC22A6

31

Q4U2R8
LHQSLPQNQCYMATT

EHMT1

256

Q9H9B1
TQRNPNARKGMASHT

MLPH

576

Q9BV36
ATNYQLPSLDFAMNH

MICAL2

346

O94851
MNPANHSQVAGFVLL

OR4D5

1

Q8NGN0
NHRQTPVSYDQGANM

RND3

151

P61587
MSHLSQQRIYSGENP

ZNF146

1

Q15072
SFHAYNRMTPQNLAV

SYDE1

541

Q6ZW31
RMGFPQHTIASLSDQ

GTF2H2C;

251

Q6P1K8
GMQARAPSQYSTRHF

SPATA6L

181

Q8N4H0
SIIHNFRANNVSPMT

PLCB4

131

Q15147
GTVIAYRQRQHQDMP

SEL1L

756

Q9UBV2
SPASLYQQNQVMHLS

RGS22

921

Q8NE09
RNFYDPTSAMVLQQH

PIWIL2

341

Q8TC59
NTANLSPDHMQRLTF

PIWIL2

911

Q8TC59
YAASHSGVVQVPMAN

SEMA4B

511

Q9NPR2
HNQSPRNTYQSAMGK

POLR2B

716

P30876
AMSALYHIAQNDSPT

TAOK3

226

Q9H2K8
DGQHFSLAMSSNRPV

SETD1B

51

Q9UPS6
PIFGDMLATANQHTQ

PKHD1

891

P08F94
PVQRHVTMSTNNRFS

TDRD7

176

Q8NHU6
RQQQMVVAHQYSFAP

TNS3

591

Q68CZ2
NQIAAAFGHMPLLSS

EXTL1

636

Q92935
GARSMSRNPFAHVQL

BAIAP2

506

Q9UQB8
VVNNMNRTALHFAVG

ANKDD1B

96

A6NHY2
NNISRILVTSFNHMP

SLIT3

191

O75094
LGHFQENMQIQSFPR

SPG11

801

Q96JI7
YMQRASDLARQINHP

TTC19

301

Q6DKK2
LTMHSIHNSQQPRNA

SPATS2

191

Q86XZ4
DQMPARSLSRGFNNH

TTC13

586

Q8NBP0
ASRDSQMQNPYSRHS

MUC13

491

Q9H3R2
LHNISPQMSAAAAAA

TLE4

396

Q04727
IPGMNTRDQYATITH

SAGE1

331

Q9NXZ1
SAMSPRDLYATINHN

SAGE2P

201

A6NJ88
RMGFPQHTIASLSDQ

GTF2H2

251

Q13888
NQRVGETFHASQPSM

SMAD3

241

P84022
YENMRFLITHNPTNA

PTP4A2

11

Q12974
ANMNRLFFQPHQAGL

UBA5

111

Q9GZZ9
PHIRSMANQLIQFNT

STAB2

606

Q8WWQ8
TSAIPQYHLAMSNGT

ZMYM6

326

O95789
VSLPGSQQHLSANMF

SH3RF2

371

Q8TEC5
SFVPTNMAVNYVQHN

C9orf78

211

Q9NZ63
QFVSQLPHMQAARGS

VPS33A

336

Q96AX1
FINVMLSHPNHTGNN

TECRL

266

Q5HYJ1
PDRQGQSSHYSQMDR

RPTN

526

Q6XPR3
MSSLQPEASARGHFQ

XIRP1

1561

Q702N8
AALSQFHMPRASQFA

ZNF318

756

Q5VUA4
MPIYNSTHVASVVNQ

HIVEP1

371

P15822
PNESNLTQLYMHLTN

TTLL7

236

Q6ZT98
RSYDFIMPNSSVHNN

ZNF518B

436

Q9C0D4