Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfolic acid receptor activity

FOLR1 FOLR2 FOLR3

4.13e-083703GO:0061714
GeneOntologyMolecularFunctionfolic acid binding

FOLR1 FOLR2 FOLR3 IZUMO1R

6.43e-0720704GO:0005542
GeneOntologyMolecularFunctionmodified amino acid binding

FOLR1 FOLR2 FOLR3 SCARB2 ADGRB1 IZUMO1R

4.38e-06122706GO:0072341
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

4.86e-0610703GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

8.87e-0612703GO:0016175
GeneOntologyMolecularFunctioncargo receptor activity

FOLR1 FOLR2 FOLR3 SCARB2 CD163

1.21e-0585705GO:0038024
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

4.51e-0520703GO:0050664
GeneOntologyMolecularFunctionendopeptidase activity

CELA3B CTSF TINAG CELA3A MMP28 CAPN3 PRSS55 CTSK

1.27e-04430708GO:0004175
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CTSF TINAG CAPN3 CTSK

2.37e-0486704GO:0004197
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 NCF1C NCF1B

2.49e-0435703GO:0043325
GeneOntologyMolecularFunctionpeptidase activity

CELA3B CTSF TINAG CELA3A UFSP2 MMP28 CAPN3 PRSS55 CTSK

4.49e-04654709GO:0008233
GeneOntologyMolecularFunctioncysteine-type peptidase activity

CTSF TINAG UFSP2 CAPN3 CTSK

5.69e-04192705GO:0008234
GeneOntologyMolecularFunctionphospholipid binding

SNX25 SCARB2 NCF1 ADGRB1 SNX9 NCF1C NCF1B TECPR1

6.48e-04548708GO:0005543
GeneOntologyMolecularFunctiondelta-catenin binding

CDH26 PTPRT

6.53e-0411702GO:0070097
GeneOntologyMolecularFunctionalpha-catenin binding

CDH26 PTPRT

7.82e-0412702GO:0045294
GeneOntologyMolecularFunctionphosphatidylinositol binding

SNX25 NCF1 SNX9 NCF1C NCF1B TECPR1

8.39e-04316706GO:0035091
GeneOntologyMolecularFunctionvitamin binding

FOLR1 FOLR2 FOLR3 IZUMO1R

2.47e-03161704GO:0019842
GeneOntologyMolecularFunctionamide binding

CLN8 FOLR1 FOLR2 FOLR3 IZUMO1R

3.98e-03299705GO:0033218
GeneOntologyMolecularFunctionscavenger receptor activity

SCARB2 CD163

4.02e-0327702GO:0005044
GeneOntologyMolecularFunctionmannosyltransferase activity

DPY19L2 DPY19L2P2

4.32e-0328702GO:0000030
GeneOntologyMolecularFunctionserine-type endopeptidase activity

CELA3B CELA3A PRSS55 CTSK

4.47e-03190704GO:0004252
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

NCF1 NCF1C NCF1B

4.54e-0395703GO:0016651
GeneOntologyMolecularFunctionhyaluronic acid binding

HAPLN2 HAPLN1

4.63e-0329702GO:0005540
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

3.73e-075703GO:0070946
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

1.30e-067703GO:0070947
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

1.30e-067703GO:0006742
GeneOntologyBiologicalProcesssperm-egg recognition

FOLR1 FOLR2 FOLR3 PRSS55 IZUMO1R

2.75e-0665705GO:0035036
GeneOntologyBiologicalProcessfusion of sperm to egg plasma membrane involved in single fertilization

FOLR1 FOLR2 FOLR3 IZUMO1R

4.62e-0633704GO:0007342
GeneOntologyBiologicalProcesscell recognition

MEGF8 FOLR1 FOLR2 FOLR3 ADGRB1 PRSS55 IZUMO1R

4.86e-06198707GO:0008037
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

6.06e-0611703GO:0060264
GeneOntologyBiologicalProcessfolic acid transport

FOLR1 FOLR2 FOLR3

6.06e-0611703GO:0015884
GeneOntologyBiologicalProcessplasma membrane fusion

FOLR1 FOLR2 FOLR3 IZUMO1R

7.38e-0637704GO:0045026
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.04e-0513703GO:0002536
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 NCF1C NCF1B GGTA1

1.12e-0541704GO:0006691
GeneOntologyBiologicalProcesscellular response to folic acid

FOLR1 FOLR2

1.14e-052702GO:0071231
GeneOntologyBiologicalProcessprotein targeting to membrane

TCAF2 TCAF1 FOLR1 FOLR2 FOLR3 NCF1

1.15e-05149706GO:0006612
GeneOntologyBiologicalProcesscell-cell recognition

FOLR1 FOLR2 FOLR3 PRSS55 IZUMO1R

1.52e-0592705GO:0009988
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

2.03e-0516703GO:0070944
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

2.95e-0518703GO:0001878
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

3.49e-0519703GO:0070943
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

4.09e-0520703GO:0002679
GeneOntologyBiologicalProcesspost-translational protein targeting to endoplasmic reticulum membrane

FOLR1 FOLR2 FOLR3

4.77e-0521703GO:0006620
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

4.77e-0521703GO:0070942
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 NCF1C NCF1B

5.50e-0522703GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

5.50e-0522703GO:0050665
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

6.31e-0523703GO:0060263
GeneOntologyBiologicalProcessdisruption of cell in another organism

NCF1 C6 C8B NCF1C NCF1B

7.74e-05129705GO:0141061
GeneOntologyBiologicalProcesskilling of cells of another organism

NCF1 C6 C8B NCF1C NCF1B

7.74e-05129705GO:0031640
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

NCF1 C6 C8B NCF1C NCF1B

8.63e-05132705GO:0141060
GeneOntologyBiologicalProcessestablishment of protein localization to membrane

TCAF2 TCAF1 FOLR1 FOLR2 FOLR3 SCARB2 NCF1

1.03e-04319707GO:0090150
GeneOntologyBiologicalProcessreactive oxygen species biosynthetic process

NCF1 ADGRB1 NCF1C NCF1B

1.58e-0480704GO:1903409
GeneOntologyBiologicalProcessprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

DPY19L2 DPY19L2P2

1.69e-046702GO:0018406
GeneOntologyBiologicalProcesspeptidyl-tryptophan modification

DPY19L2 DPY19L2P2

1.69e-046702GO:0018211
GeneOntologyBiologicalProcessprotein C-linked glycosylation

DPY19L2 DPY19L2P2

1.69e-046702GO:0018103
GeneOntologyBiologicalProcessprotein C-linked glycosylation via tryptophan

DPY19L2 DPY19L2P2

1.69e-046702GO:0018317
GeneOntologyBiologicalProcessregulation of anion channel activity

TCAF2 TCAF1

1.69e-046702GO:0010359
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1 NCF1C NCF1B

2.27e-0435703GO:0045932
GeneOntologyBiologicalProcessprotein targeting

TCAF2 TCAF1 FOLR1 FOLR2 FOLR3 SCARB2 NCF1

2.69e-04373707GO:0006605
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 NCF1C NCF1B

2.90e-0438703GO:0051873
GeneOntologyBiologicalProcessregulation of monoatomic anion transmembrane transport

TCAF2 TCAF1

3.14e-048702GO:1903959
GeneOntologyBiologicalProcessrespiratory burst

NCF1 NCF1C NCF1B

4.19e-0443703GO:0045730
GeneOntologyBiologicalProcessplasma membrane organization

FOLR1 FOLR2 FOLR3 SNX9 IZUMO1R

4.47e-04188705GO:0007009
GeneOntologyBiologicalProcessmodified amino acid transport

FOLR1 FOLR2 FOLR3

4.49e-0444703GO:0072337
GeneOntologyBiologicalProcessneutrophil mediated immunity

NCF1 NCF1C NCF1B

5.80e-0448703GO:0002446
GeneOntologyBiologicalProcesscell killing

NCF1 C6 C8B NCF1C NCF1B CLEC2A

6.10e-04307706GO:0001906
GeneOntologyBiologicalProcesssuperoxide anion generation

NCF1 NCF1C NCF1B

6.54e-0450703GO:0042554
GeneOntologyBiologicalProcesssingle fertilization

FOLR1 FOLR2 FOLR3 PRSS55 IZUMO1R

7.22e-04209705GO:0007338
GeneOntologyBiologicalProcessresponse to folic acid

FOLR1 FOLR2

7.33e-0412702GO:0051593
GeneOntologyBiologicalProcessprotein targeting to ER

FOLR1 FOLR2 FOLR3

7.34e-0452703GO:0045047
GeneOntologyBiologicalProcessdicarboxylic acid transport

CLN8 FOLR1 FOLR2 FOLR3

7.43e-04120704GO:0006835
GeneOntologyBiologicalProcesspharyngeal arch artery morphogenesis

MEGF8 FOLR1

8.64e-0413702GO:0061626
GeneOntologyBiologicalProcessestablishment of protein localization to endoplasmic reticulum

FOLR1 FOLR2 FOLR3

9.12e-0456703GO:0072599
GeneOntologyBiologicalProcessvitamin transport

FOLR1 FOLR2 FOLR3

9.12e-0456703GO:0051180
GeneOntologyBiologicalProcessNADP metabolic process

NCF1 NCF1C NCF1B

9.12e-0456703GO:0006739
GeneOntologyBiologicalProcessinnate immune response

UBA7 NCF1 ADGRB1 TRIM49D1 BIRC3 SRPK2 C6 C8B NCF1C NCF1B CLEC2A

1.07e-0310927011GO:0045087
GeneOntologyBiologicalProcesscellular defense response

NCF1 NCF1C NCF1B

1.12e-0360703GO:0006968
GeneOntologyBiologicalProcessicosanoid metabolic process

NCF1 NCF1C NCF1B GGTA1

1.39e-03142704GO:0006690
GeneOntologyBiologicalProcesshydrogen peroxide metabolic process

NCF1 NCF1C NCF1B

1.54e-0367703GO:0042743
GeneOntologyBiologicalProcessregulation of monoatomic anion transport

TCAF2 TCAF1

1.68e-0318702GO:0044070
GeneOntologyBiologicalProcessdefense response to fungus

NCF1 NCF1C NCF1B

1.81e-0371703GO:0050832
GeneOntologyBiologicalProcessG1 to G0 transition

WDR6 CAPN3

1.87e-0319702GO:0070314
GeneOntologyBiologicalProcessfertilization

FOLR1 FOLR2 FOLR3 PRSS55 IZUMO1R

2.00e-03263705GO:0009566
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

DPY19L2 FOLR1 FOLR2 FOLR3 CATSPER4 DPY19L2P2 IZUMO1R

2.04e-03527707GO:0022412
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

2.83e-0518703GO:0043020
GeneOntologyCellularComponentmembrane attack complex

C6 C8B

2.30e-047702GO:0005579
GeneOntologyCellularComponentcollagen-containing extracellular matrix

CELA3B CTSF TINAG CELA3A HMCN1 MMP28 HAPLN2 HAPLN1

3.85e-04530708GO:0062023
GeneOntologyCellularComponentperineuronal net

HAPLN2 HAPLN1

4.89e-0410702GO:0072534
GeneOntologyCellularComponentperisynaptic extracellular matrix

HAPLN2 HAPLN1

5.96e-0411702GO:0098966
GeneOntologyCellularComponentside of membrane

FOLR1 FOLR2 FOLR3 NCF1 PRSS55 IZUMO1R NCF1C NCF1B CTSK CD163

6.38e-048757010GO:0098552
GeneOntologyCellularComponentsynapse-associated extracellular matrix

HAPLN2 HAPLN1

8.42e-0413702GO:0099535
GeneOntologyCellularComponentextracellular matrix

CELA3B CTSF TINAG CELA3A HMCN1 MMP28 HAPLN2 HAPLN1

1.53e-03656708GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CELA3B CTSF TINAG CELA3A HMCN1 MMP28 HAPLN2 HAPLN1

1.56e-03658708GO:0030312
GeneOntologyCellularComponentcalcium channel complex

CATSPER4 PKD1L1 PKD1

1.89e-0373703GO:0034704
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.21e-066563MP:0003184
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.21e-066563MP:0013254
MousePhenoliver abscess

NCF1 NCF1C NCF1B

2.11e-067563MP:0003332
MousePhenoimpaired granulocyte bactericidal activity

NCF1 NCF1C NCF1B

7.16e-0610563MP:0005074
MousePhenoenhanced long-term potentiation

NCF1 ADGRB1 NCF1C NCF1B PTPRT

7.95e-0669565MP:0003008
MousePhenodecreased susceptibility to Orthomyxoviridae infection

NCF1 NCF1C NCF1B

4.76e-0518563MP:0020947
MousePhenodecreased vasoconstriction

NCF1 NCF1C NCF1B

8.88e-0522563MP:0003026
MousePhenoabsent mandibular angle

HHAT CTSK

9.41e-054562MP:0004913
MousePhenoabnormal sperm individualization

DPY19L2 DPY19L2P2

9.41e-054562MP:0031372
MousePhenoincreased circulating renin level

NCF1 NCF1C NCF1B

1.02e-0423563MP:0003352
MousePhenoabnormal bile duct morphology

NCF1 PKD1 NCF1C NCF1B

1.23e-0464564MP:0002928
MousePhenoabnormal bone marrow cavity morphology

PKD1 LRRK1 CTSK

1.66e-0427563MP:0000065
MousePhenoabnormal circulating renin level

NCF1 NCF1C NCF1B

2.07e-0429563MP:0003349
MousePhenoimpaired smooth muscle contractility

NCF1 NCF1C NCF1B

3.64e-0435563MP:0000740
MousePhenogranulomatous inflammation

NCF1 NCF1C NCF1B

3.96e-0436563MP:0002500
MousePhenoabnormal macrophage physiology

MMP28 NCF1 BIRC3 LRRK1 NCF1C NCF1B CTSK CD163

4.02e-04451568MP:0002451
MousePhenoenlarged kidney

CLN8 ZBED4 SCARB2 NCF1 PKD1 NCF1C NCF1B

5.02e-04354567MP:0003068
DomainFolate_rcpt

FOLR1 FOLR2 FOLR3 IZUMO1R

7.09e-105664IPR004269
DomainTSP_1

HMCN1 ADGRB1 ADGRB2 C6 C8B ISM2 UNC5D

2.35e-0963667PF00090
DomainTSP1

HMCN1 ADGRB1 ADGRB2 C6 C8B ISM2 UNC5D

2.94e-0965667SM00209
DomainTSP1_rpt

HMCN1 ADGRB1 ADGRB2 C6 C8B ISM2 UNC5D

2.94e-0965667IPR000884
DomainTSP1

HMCN1 ADGRB1 ADGRB2 C6 C8B ISM2 UNC5D

2.94e-0965667PS50092
DomainFolate_rcpt-like

FOLR1 FOLR2 FOLR3 IZUMO1R

9.85e-098664IPR018143
DomainFolate_rec

FOLR1 FOLR2 FOLR3 IZUMO1R

9.85e-098664PF03024
DomainTHIOL_PROTEASE_ASN

CTSF TINAG CAPN3 CTSK

2.35e-0627664PS00640
DomainPept_cys_AS

CTSF TINAG CAPN3 CTSK

2.73e-0628664IPR000169
DomainGPS

PKD1L1 PKD1 ADGRB1 ADGRB2

7.69e-0636664PS50221
DomainGPS

PKD1L1 PKD1 ADGRB1 ADGRB2

8.60e-0637664IPR000203
DomainPept_C1

CTSF TINAG CTSK

1.18e-0513663SM00645
DomainPeptidase_C1A_C

CTSF TINAG CTSK

1.18e-0513663IPR000668
DomainPeptidase_C1

CTSF TINAG CTSK

1.18e-0513663PF00112
DomainPeptidase_C1A

CTSF TINAG CTSK

1.18e-0513663IPR013128
DomainPeptidase_M60_dom

TCAF2 TCAF1

1.23e-052662IPR031161
DomainPeptidase_M60

TCAF2 TCAF1

1.23e-052662PF13402
DomainM60-like

TCAF2 TCAF1

1.23e-052662SM01276
DomainPEPTIDASE_M60

TCAF2 TCAF1

1.23e-052662PS51723
DomainGPCR_2_brain_angio_inhib

ADGRB1 ADGRB2

3.68e-053662IPR008077
DomainREJ

PKD1L1 PKD1

7.35e-054662PS51111
DomainREJ_dom

PKD1L1 PKD1

7.35e-054662IPR014010
DomainTHIOL_PROTEASE_CYS

CTSF CAPN3 CTSK

1.03e-0426663PS00139
DomainTHIOL_PROTEASE_HIS

CTSF CAPN3 CTSK

1.16e-0427663PS00639
DomainPKD/REJ-like

PKD1L1 PKD1

1.83e-046662IPR002859
DomainREJ

PKD1L1 PKD1

1.83e-046662PF02010
DomainMACPF_CS

C6 C8B

1.83e-046662IPR020863
DomainGPS

PKD1 ADGRB1 ADGRB2

2.33e-0434663SM00303
DomainGPS

PKD1 ADGRB1 ADGRB2

2.54e-0435663PF01825
DomainInhibitor_I29

CTSF CTSK

2.55e-047662PF08246
DomainProt_inhib_I29

CTSF CTSK

2.55e-047662IPR013201
DomainPKD

PKD1L1 PKD1

2.55e-047662PF00801
DomainInhibitor_I29

CTSF CTSK

2.55e-047662SM00848
DomainMACPF_2

C6 C8B

2.55e-047662PS51412
DomainMACPF_1

C6 C8B

2.55e-047662PS00279
Domain-

PKD1 HAPLN2 CLEC2A HAPLN1

3.85e-04976643.10.100.10
DomainC-type_lectin-like/link

PKD1 HAPLN2 CLEC2A HAPLN1

4.16e-0499664IPR016186
DomainPKD/Chitinase_dom

PKD1L1 PKD1

4.36e-049662IPR022409
DomainPKD

PKD1L1 PKD1

4.36e-049662SM00089
DomainPX

SNX25 NCF1 SNX9

5.03e-0444663SM00312
DomainPept_asp_AS

TINAG CTSK

5.43e-0410662IPR025661
DomainMAC_perforin

C6 C8B

5.43e-0410662IPR001862
DomainCTDL_fold

PKD1 HAPLN2 CLEC2A HAPLN1

5.59e-04107664IPR016187
DomainLDLRA_1

PKD1 C6 C8B

6.51e-0448663PS01209
DomainPept_his_AS

CTSF CTSK

6.63e-0411662IPR025660
DomainMACPF

C6 C8B

6.63e-0411662PF01823
DomainGAIN_dom_N

ADGRB1 ADGRB2

6.63e-0411662IPR032471
DomainPKD

PKD1L1 PKD1

6.63e-0411662PS50093
DomainPKD_dom

PKD1L1 PKD1

6.63e-0411662IPR000601
DomainPKD_channel

PKD1L1 PKD1

6.63e-0411662PF08016
DomainGAIN

ADGRB1 ADGRB2

6.63e-0411662PF16489
DomainPKD1_2_channel

PKD1L1 PKD1

6.63e-0411662IPR013122
Domain-

PKD1L1 PKD1

6.63e-04116622.60.40.670
DomainPX

SNX25 NCF1 SNX9

6.91e-0449663PF00787
DomainLDLRA_2

PKD1 C6 C8B

6.91e-0449663PS50068
DomainPX

SNX25 NCF1 SNX9

7.34e-0450663PS50195
Domain-

SNX25 NCF1 SNX9

7.78e-04516633.30.1520.10
DomainMACPF

C6 C8B

7.93e-0412662SM00457
DomainClass_I_gatase-like

TCAF2 TCAF1

7.93e-0412662IPR029062
DomainMACPF

C6 C8B

7.93e-0412662IPR020864
DomainPhox

SNX25 NCF1 SNX9

8.23e-0452663IPR001683
DomainLINK

HAPLN2 HAPLN1

9.36e-0413662SM00445
DomainLink_dom

HAPLN2 HAPLN1

9.36e-0413662IPR000538
DomainXlink

HAPLN2 HAPLN1

9.36e-0413662PF00193
DomainLINK_1

HAPLN2 HAPLN1

9.36e-0413662PS01241
DomainLINK_2

HAPLN2 HAPLN1

9.36e-0413662PS50963
DomainLH2

PKD1L1 PKD1

1.81e-0318662SM00308
DomainEGF-like_dom

ITGBL1 HMCN1 MEGF8 C6 C8B

1.87e-03249665IPR000742
DomainEGF_1

ITGBL1 HMCN1 MEGF8 C6 C8B

2.07e-03255665PS00022
DomainIGv

HMCN1 HAPLN2 HAPLN1

2.37e-0375663SM00406
DomainEGF_2

ITGBL1 HMCN1 MEGF8 C6 C8B

2.45e-03265665PS01186
DomainPLAT

PKD1L1 PKD1

2.47e-0321662PS50095
Domain-

PKD1L1 PKD1

2.47e-03216622.60.60.20
DomainPLAT

PKD1L1 PKD1

2.47e-0321662PF01477
DomainPLAT/LH2_dom

PKD1L1 PKD1

2.47e-0321662IPR001024
DomainQuino_amine_DH_bsu

WDR6 LRRK1

2.71e-0322662IPR011044
DomainHormR

ADGRB1 ADGRB2

3.50e-0325662SM00008
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

2.52e-069453MM14524
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

NCF1 NCF1C NCF1B

6.66e-0525453MM15269
PathwayWP_FOLATE_METABOLISM

FOLR1 FOLR2 FOLR3 IZUMO1R

6.73e-0569454M39617
PathwayBIOCARTA_FMLP_PATHWAY

NCF1 NCF1C NCF1B

1.70e-0434453MM1399
PathwayREACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES

NCF1 NCF1C NCF1B

1.85e-0435453MM14944
PathwayBIOCARTA_PEPI_PATHWAY

CELA3B CELA3A

2.07e-047452MM1589
PathwayKEGG_MEDICUS_REFERENCE_COMMON_PATHWAY_OF_COMPLEMENT_CASCADE_MAC_FORMATION

C6 C8B

2.07e-047452M47873
PathwayREACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

NCF1 NCF1C NCF1B

2.37e-0438453MM14519
PathwayREACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT

C6 C8B

2.76e-048452M27006
PathwayREACTOME_TERMINAL_PATHWAY_OF_COMPLEMENT

C6 C8B

2.76e-048452MM14656
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_MAC_INHIBITION

C6 C8B

3.54e-049452M47881
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

NCF1 NCF1C NCF1B

4.19e-0446453MM15837
Pubmed

Identification of two putative novel folate receptor genes in humans and mouse.

FOLR1 FOLR2 FOLR3 IZUMO1R

1.59e-11471411111049
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

FOLR1 FOLR2 FOLR3 IZUMO1R

1.11e-09871422365888
Pubmed

Neutrophil-activating therapy for the treatment of cancer.

NCF1 C6 NCF1C NCF1B

5.20e-091171436706760
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

8.15e-09371318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

8.15e-09371310678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

8.15e-09371327044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

8.15e-09371317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

8.15e-09371324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

8.15e-09371310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

8.15e-09371325474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

8.15e-09371318787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

8.15e-09371326209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

8.15e-09371324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

8.15e-09371322184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

8.15e-09371311018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

8.15e-09371333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

8.15e-09371320142487
Pubmed

Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.

FOLR1 FOLR2 FOLR3

8.15e-0937138304978
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.15e-0937139116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

8.15e-09371320686129
Pubmed

Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.

FOLR1 FOLR2 FOLR3

8.15e-0937131894617
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

8.15e-09371321570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

8.15e-09371325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

8.15e-09371339357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

8.15e-09371312958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

8.15e-09371311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

8.15e-09371331118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

8.15e-09371323482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

8.15e-09371316041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

8.15e-09371310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

8.15e-09371310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

8.15e-09371321435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

8.15e-09371318703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

8.15e-09371329228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

8.15e-09371317307863
Pubmed

Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta.

FOLR1 FOLR2 FOLR3

8.15e-0937139166787
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

8.15e-09371322155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

8.15e-09371327829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

8.15e-09371324576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

8.15e-09371322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

8.15e-09371323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

8.15e-09371328274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

8.15e-09371326645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

8.15e-09371312364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

8.15e-09371324549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

8.15e-09371334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

8.15e-09371328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

8.15e-09371310670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

8.15e-09371320881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

8.15e-09371326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

8.15e-09371319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

8.15e-09371320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

8.15e-09371323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

8.15e-09371334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

8.15e-09371317114280
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

8.15e-09371319168575
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

8.15e-09371325989352
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

8.15e-09371319503084
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

8.15e-09371317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

8.15e-09371317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

8.15e-09371336592568
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

8.15e-09371311156938
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

8.15e-09371330504842
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

8.15e-09371310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

8.15e-09371327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

8.15e-09371320702812
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

8.15e-09371333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

8.15e-09371323965970
Pubmed

Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth.

FOLR2 FOLR3 IZUMO1R

8.15e-09371337928524
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

8.15e-09371326455429
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

8.15e-09371315513930
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

8.15e-09371315626477
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

8.15e-09371315033459
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

8.15e-09371319077231
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

8.15e-09371320828610
Pubmed

Renal tubular reabsorption of folate mediated by folate binding protein 1.

FOLR1 FOLR2 FOLR3

8.15e-09371315703271
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

8.15e-09371320817944
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

8.15e-09371322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1 NCF1C NCF1B

8.15e-09371316895801
Pubmed

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.

NCF1 NCF1C NCF1B

8.15e-09371320690191
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1 NCF1C NCF1B

8.15e-09371316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1 NCF1C NCF1B

8.15e-09371332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1 NCF1C NCF1B

8.15e-09371316280459
Pubmed

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

NCF1 NCF1C NCF1B

8.15e-09371318185592
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

8.15e-09371336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

8.15e-09371323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

8.15e-09371321253614
Pubmed

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

NCF1 NCF1C NCF1B

8.15e-09371325873172
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

8.15e-09371315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

8.15e-09371331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

8.15e-09371310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

8.15e-09371334970267
Pubmed

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

FOLR1 FOLR2 FOLR3

8.15e-09371315694460
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

8.15e-09371325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

8.15e-09371314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

8.15e-09371322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

8.15e-09371312031896
Pubmed

Expression patterns of folate binding proteins one and two in the developing mouse embryo.

FOLR1 FOLR2 FOLR3

8.15e-0937139973545
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

8.15e-09371311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

8.15e-09371315936744
Cytoband7q11.23

NCF1 NCF1C NCF1B

4.71e-04977137q11.23
Cytoband12p13.3

PARP11 CD163

9.97e-043071212p13.3
Cytoband1p35.3

CATSPER4 ARID1A

1.28e-03347121p35.3
Cytoband4q35.1

UFSP2 SNX25

1.44e-03367124q35.1
Cytoband1p36.12

CELA3B CELA3A

1.68e-03397121p36.12
CytobandEnsembl 112 genes in cytogenetic band chr12p13

PARP11 ACSM4 CD163 CLEC2A

2.23e-03353714chr12p13
Cytoband7q35

TCAF2 TCAF1

3.32e-03557127q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

TCAF2 TCAF1

4.74e-0366712chr7q35
CytobandEnsembl 112 genes in cytogenetic band chr7q22

SRPK2 DPY19L2P2 CUX1

4.82e-03219713chr7q22
CytobandEnsembl 112 genes in cytogenetic band chr11q13

CTSF FOLR1 FOLR2 FOLR3

5.44e-03454714chr11q13
Cytoband12p13.31

ACSM4 CLEC2A

6.89e-038071212p13.31
GeneFamilyAdhesion G protein-coupled receptors, subfamily B

ADGRB1 ADGRB2

1.50e-053412912
GeneFamilyCathepsins

CTSF CTSK

5.17e-0415412470
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARB2 CD163

1.70e-03274121253
GeneFamilySorting nexins|PX-BAR domain containing

SNX25 SNX9

1.96e-0329412754
GeneFamilyComplement system|Sushi domain containing

C6 C8B

3.01e-0336412492
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

WDR6 HHAT SCARB2 NCF1 ANAPC11 BIRC3 SRPK2 XPO1 ARID1A IZUMO1R NCF1C NCF1B GGTA1

3.83e-0610726913MM1031
CoexpressionNABA_MATRISOME

CELA3B CTSF TINAG CELA3A HMCN1 MEGF8 MMP28 HAPLN2 ISM2 CTSK CLEC2A HAPLN1

1.36e-0510266912M5889
CoexpressionGAVIN_PDE3B_TARGETS

NCF1 NCF1C NCF1B

3.85e-0525693MM726
CoexpressionNABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS

CELA3B CELA3A HMCN1

4.35e-0526693MM17051
CoexpressionNABA_MATRISOME

CELA3B CTSF TINAG CELA3A HMCN1 MEGF8 MMP28 HAPLN2 ISM2 CTSK HAPLN1

6.09e-0510086911MM17056
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

WDR6 HHAT SCARB2 NCF1 ANAPC11 BIRC3 SRPK2 XPO1 ARID1A IZUMO1R GGTA1

7.02e-0510246911M1742
CoexpressionDESCARTES_ORGANOGENESIS_EPENDYMAL_CELL

DPY19L2 FOLR1 FOLR2 FOLR3 ISM2 DPY19L2P2

9.99e-05282696MM3642
CoexpressionGSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN

PARP11 SNX25 BIRC3 SNX9 NCF1C

1.65e-04195695M4233
CoexpressionGSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_DN

CTSF CELA3A FOLR3 NCF1C HAPLN1

1.73e-04197695M7255
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P4

NCF1 CAPN3 NCF1C NCF1B

1.78e-04106694MM1216
CoexpressionGSE360_DC_VS_MAC_T_GONDII_DN

FOLR2 FOLR3 CTSK CD163 HAPLN1

1.82e-04199695M5184
CoexpressionGSE14308_TH1_VS_TH17_DN

TINAG NUAK1 PKD1 ZNF629 ARID1A

1.86e-04200695M3374
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP

MEGF8 NUAK1 PKD1 ZNF629 SNX9

1.86e-04200695M6629
CoexpressionGSE18893_TCONV_VS_TREG_2H_CULTURE_DN

UBA7 SCARB2 NCF1 XPO1 SNX9

1.86e-04200695M7293
CoexpressionGSE3982_DC_VS_TH1_UP

CLN8 SCARB2 CAPN3 SRPK2 CUX1

1.86e-04200695M5481
ToppCell367C|World / Donor, Lineage, Cell class and subclass (all cells)

ITGBL1 CTSF HMCN1 FOLR2 CTSK CD163

7.60e-07198716ab3a178f392204e2d90eb5a3b5de7849986b1eaf
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-6|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

FOLR2 NCF1 NCF1C NCF1B GGTA1

2.01e-061297156071762027460b97c6642c58d06992f2b2703186
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR1 FOLR2 C6 CD163

4.63e-061537154b999892fb797e9f0d391630094f466463299d57
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR1 FOLR2 C6 CD163

4.63e-06153715e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR1 FOLR2 C6 CD163

4.63e-06153715668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TINAG SNX25 C6 ISM2 UNC5D

7.73e-061707154ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 SRPK2 LRRK1

1.19e-051867152d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellBronchial_Brush-Immune-Luminal_Macrophages|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

FOLR2 FOLR3 NCF1 C8B CD163

1.36e-0519171588cb6f828407845918c946f8cee5f940cb81800a
ToppCelldistal-Hematologic-Interstitial_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLR2 NCF1 NCF1C NCF1B CTSK

1.54e-05196715e4f40274df940e0996c555082f2bb4f99e5b0881
ToppCellBAL-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

FOLR2 FOLR3 SCARB2 NCF1 CD163

1.65e-051997154518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACSM4 DPY19L2 FOLR1

3.30e-053971366fe368f1dfe665c661cf9baf854d12eb28c25b8
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACSM4 DPY19L2 FOLR1

3.30e-0539713d5b0bcdfb27c881049178079c48deb587a0b2fda
ToppCellCOVID-19-kidney-Epithelial_Doublet|kidney / Disease (COVID-19 only), tissue and cell type

ACSM4 NCF1 IZUMO1R PTPRT

4.63e-05124714d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCellBLOOD--(3)_MNP-(3)_Classical_Mono-1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FOLR3 NCF1 XPO1 CD163

7.84e-05142714395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCellfacs-Skin-Anagen-3m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

8.06e-05143714250f60f06f262f00acd14b09b3ef90dbb9759336
ToppCellfacs-Skin-Anagen-3m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

8.06e-051437140c7c0d7ca040e87412295672cd1f065c0e941391
ToppCellfacs-Skin-Anagen-3m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

8.06e-0514371427f4896276342758651fe7a80d7408ac5e1be9c0
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ITGBL1 HMCN1 CTSK PTPRT

9.45e-051497143904f8ce9078de238600ceceee0116af52256a1c
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C17orf78 C6

1.05e-04153714af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C17orf78 C6

1.05e-04153714984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

FOLR2 SNX25 CD163 B3GALT5-AS1

1.05e-041537145424494ea1f09542799045a875cc3eac13de5079
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

CLN8 FOLR1 SRPK3 HAPLN1

1.13e-04156714b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBED4 NUAK1 SNX25 LRRK1

1.16e-04157714ec433d2fe827abdb647be4176c231b7052482b6f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 SNX25 C6 CD163

1.16e-04157714b527e88382c8d21188a0f222b3302523e8816dfc
ToppCelldroplet-Fat-Gat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 C6 PTPRT CD163

1.30e-04162714052f797d8bcab8fc6a43e0bffdd215c88ee12889
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSF FOLR2 C8B CTSK

1.30e-041627142787be283b7a705647058aeb9bc54006ce5ffe95
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 FOLR2 FOLR3 CD163

1.37e-04164714d7053de88ef8e42cac6726a40e72f212659ee034
ToppCelldroplet-Limb_Muscle-nan-21m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.40e-04165714c2fc76feff58d77128f5a5318fed9c265574d760
ToppCelldroplet-Limb_Muscle-nan-21m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.40e-041657145f23173ec624ea7f893d22e326446f0e39e30b4e
ToppCelldroplet-Limb_Muscle-nan-21m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.40e-041657141760ec2ac8913a2b33f46672a3f39ca7489966b8
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

FOLR3 NCF1 XPO1 CD163

1.47e-041677147d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCelldroplet-Fat-Scat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.50e-04168714749eccebe4ee066f827d2a3980512f195f23ac27
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

MMP28 UNC5D B3GALT5-AS1 HAPLN1

1.50e-041687145ce3129a023a48a3d7e6b9306c1fc5addfef9675
ToppCellTCGA-Pancreas|World / Sample_Type by Project: Shred V9

CELA3B ITGBL1 CELA3A C6

1.50e-04168714279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.53e-0416971444d841fd997a6f26104f16cd00223ecce8352f43
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.53e-041697140f5e737b265ba333275a0cd289dab029a1542075
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.53e-04169714aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12-45|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLN8 FOLR2 NCF1 CD163

1.57e-04170714e028e22ad051c2628248b212b5d28b891e0ee782
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 LRRK1 C6 CD163

1.64e-041727141f335ccb92b22d0412954e8fc3af212f96410b67
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

ITGBL1 FOLR2 NCF1 COPB2

1.64e-04172714c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 LRRK1 C6 CD163

1.64e-04172714bb96c896d125e10b71e94e2bdad243899045af5c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.68e-041737141ea8b8b89611bebf6acb700fb04a7d38720775a9
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.68e-041737149b957dd442f3af0e5fb99f3c93606308a459d485
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.68e-04173714a664dbd7fb55b1c4309fa5f9425bc83924dac545
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR2 NCF1 C6 CD163

1.68e-04173714a0e4d25db186b9f7ff819abc0db68ad58c92ba3b
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.68e-04173714054f64462b648ba6b4b28b48c716dc01b2ddd790
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLN8 FOLR2 NCF1 CD163

1.68e-041737149a8fec9a08bb61456a4ea43ae1316bd3e197a773
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAG FOLR2 C6 CD163

1.72e-04174714dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FOLR2 FOLR3 C8B CD163

1.75e-041757141cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

CLN8 SCARB2 ZNF629 LRRK1

1.75e-0417571429fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK1 UNC5D PTPRT CUX1

1.83e-04177714f902600c639087664316b3cf30cab243bc3d1c5c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 FOLR2 C6 CD163

1.83e-0417771443883b65b1e03043a24fc40c84c50bac81960c12
ToppCelldroplet-Lung-LUNG-30m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOLR1 FOLR2 C6 CD163

1.83e-041777149de6a82b7fb72d20361947f7ac95bb1fa73fc2ff
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOLR2 NCF1 PRSS55 CD163

1.87e-0417871424e8c62060455159235985f456af0c5023a7f3f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOLR2 NCF1 PRSS55 CD163

1.87e-041787144f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 NUAK1 FOLR1 ADGRB2

1.87e-04178714c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSF WDR6 FOLR2 CD163

1.91e-041797142c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSF WDR6 FOLR2 CD163

1.91e-041797146eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOLR1 FOLR2 C6 CD163

1.91e-0417971413d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ITGBL1 UNC5D PTPRT CUX1

1.99e-04181714c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAG FOLR3 BIRC3 IZUMO1R

2.04e-04182714b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FOLR2 NCF1 LRRK1 CD163

2.08e-0418371424679153b654c148dbd572e9013c0a6e58718ada
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

ITGBL1 PPP1R18 BIRC3 CTSK

2.08e-0418371406e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FOLR2 NCF1 BIRC3 CD163

2.08e-04183714ffa7f2b2929ea4bd53f3f1ae23bd27f8bb4aac47
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NUAK1 LRRK1 UNC5D PTPRT

2.08e-04183714274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTSF TCAF1 CDH26 NUAK1

2.08e-04183714351d575339038bd4a66f408da518c567444208e8
ToppCellfacs-Thymus|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELA3B CAPN3 IZUMO1R TECPR1

2.12e-0418471458beef66bbbde2479ec69dfef392d5941cedf230
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FOLR2 NCF1 BIRC3 CD163

2.17e-041857145ec2c3ae5c477645241e8eaf19d222562e1f7ed6
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FOLR2 LRRK1 SNX9 CD163

2.17e-041857148207f9eff113eed429e961748c6b17d672a13b33
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 SRPK2

2.21e-0418671492092f11ecce22c14f244e42c499af0822977e6f
ToppCelllymphoid-B_cell-Naive_B_cell|World / Lineage, cell class and subclass

CLN8 NCF1 BIRC3 SNX9

2.26e-04187714904ffd8cf4513e86fcd4c2b7faf24a34fbd2dce3
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PARP11 SCARB2 TRIM49D1 CD163

2.26e-0418771472e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCelllymphoid-B_cell|World / Lineage, cell class and subclass

CLN8 NCF1 BIRC3 SNX9

2.26e-041877142abbc01fd7f5b4e52113699625287893c991f8da
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ITGBL1 HMCN1 NUAK1 CTSK

2.26e-04187714a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 LRRK1

2.35e-04189714c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ITGBL1 FOLR1 CTSK PTPRT

2.40e-041907143aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCelllymphoid-B_cell-Naive_B_cell|lymphoid / Lineage, cell class and subclass

CLN8 NCF1 BIRC3 SNX9

2.40e-04190714b8b05894e811e431d797ac4fa3ccff4963a154e7
ToppCelllymphoid-B_cell|lymphoid / Lineage, cell class and subclass

CLN8 NCF1 BIRC3 SNX9

2.40e-04190714c451de643ee08c2ff1093e807c65d724237473c5
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 LRRK1

2.40e-04190714aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ITGBL1 FOLR1 FOLR2 CD163

2.40e-04190714cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell390C-Myeloid-Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

FOLR2 FOLR3 C8B CD163

2.40e-04190714f933d971f092c4e56e9f670a9205b688c8b1ca28
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 LRRK1

2.45e-041917144b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDH26 FOLR2 NCF1 NCF1B

2.50e-041927145ea1a8119012eb8bc3100b739a0430377a8ac534
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 C6

2.50e-0419271481baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 C6

2.50e-04192714717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FOLR3 SCARB2 C8B CD163

2.55e-04193714c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOLR1 MMP28 SNX25 CAPN3

2.55e-04193714136775166ecc38399091f262279180dbe5a1dcd7
ToppCellCOVID-19-Myeloid-TRAM1|Myeloid / Condition, Lineage and Cell class

CTSF FOLR1 FOLR3 C8B

2.55e-041937146e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOLR1 SNX25 CAPS C6

2.55e-04193714bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 NUAK1 MMP28 C6

2.55e-041937147261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCF1 LRRK1 NCF1C NCF1B

2.60e-04194714ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PARP11 SCARB2 NCF1 CD163

2.60e-04194714e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN1 NCF1C NCF1B PTPRT

2.65e-04195714d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FOLR3 NCF1C NCF1B CD163

2.65e-04195714b0dbaae86f5703ab62f925e0f36500274044884a
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN1 NCF1C NCF1B PTPRT

2.65e-0419571419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell390C-Myeloid-Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FOLR2 SCARB2 C8B CD163

2.65e-04195714ba494be431916d43c1d480f65bed674c0722c710
ToppCellPCW_10-12-Hematologic_Myeloid|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FOLR2 NCF1 BIRC3 CD163

2.65e-041957146352cd749091cfdbf5cce3c354fa57883cc513e8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FOLR2 NCF1 NCF1C NCF1B

2.65e-04195714de47651c84da62f273535fc80115f0154746699d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOLR2 NCF1 LRRK1 CD163

2.65e-0419571434a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGBL1 CTSF CTSK HAPLN1

2.70e-04196714e7bfd4fb400ae0c473131d0fa306c26be08a6d03
DrugCalpain inhibitor I

CTSF UBA7 SCARB2 CAPN3 COPB2 BIRC3 CTSK CUX1

2.31e-06280708CID000004332
DrugFolic Acid

FOLR2 FOLR3

9.32e-062702DB00158
Drugpyrithyldione

FOLR3 HHAT

2.79e-053702CID000004994
Drugkalypnon

FOLR3 HHAT

2.79e-053702CID000018045
Drugraloxifene hydrochloride; Up 200; 0.1uM; HL60; HG-U133A

FOLR1 ADGRB2 C8B PTPRT CUX1 CD163

3.22e-05197706388_UP
DrugLY254155

FOLR1 FOLR2 FOLR3

3.56e-0521703CID009803760
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

1.12e-075673DOID:3265 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 NCF1C NCF1B

2.43e-0612673DOID:7148 (implicated_via_orthology)
Diseasestomach cancer (is_marker_for)

ADGRB1 XPO1 ARID1A CUX1

3.11e-04142674DOID:10534 (is_marker_for)
Diseasegastric adenocarcinoma (is_marker_for)

XPO1 ARID1A

1.85e-0328672DOID:3717 (is_marker_for)
DiseaseIniencephaly

FOLR1 FOLR2

1.85e-0328672C0152234
DiseaseTethered Cord Syndrome

FOLR1 FOLR2

1.85e-0328672C0080218
DiseaseSpinal Cord Myelodysplasia

FOLR1 FOLR2

1.85e-0328672C0344479
DiseaseExencephaly

FOLR1 FOLR2

1.85e-0328672C0266453
DiseaseNeurenteric Cyst

FOLR1 FOLR2

1.85e-0328672C0027806
DiseaseAcrania

FOLR1 FOLR2

1.85e-0328672C0702169
DiseaseDiastematomyelia

FOLR1 FOLR2

1.85e-0328672C0011999
DiseaseCraniorachischisis

FOLR1 FOLR2

1.98e-0329672C0152426
DiseaseNeural Tube Defects

FOLR1 FOLR2

2.12e-0330672C0027794

Protein segments in the cluster

PeptideGeneStartEntry
WNAWSLCSKTCDTGW

ADGRB2

481

O60241
HWIIKNSWGENWGNK

CTSK

291

P43235
ETGECWNGLWKSKWI

CAPZA3

161

Q96KX2
KCWNGVATWLWVAND

ANAPC11

6

Q9NYG5
KAWWQQWTSHTGLEG

CATSPER4

6

Q7RTX7
NGFWIFWKDGWNILN

CATSPER4

146

Q7RTX7
QALWGWQLSKQSGWA

CAPS

11

Q13938
QAHWGCWQNSAVWGC

B3GALT5-AS1

86

P59052
VDGKWQAWASWGSCS

ADGRB1

521

O14514
WDWDKKWSCSQVFEG

COPB2

126

P35606
KNEVGRSGAWKDHWW

CUX1

811

P39880
CQCQWLWRWQKKGGQ

C17orf78

221

Q8N4C9
CWESGDDPWVQHAKW

BIRC3

301

Q13489
ALWWVNGKGDEVKWS

ACSM4

76

P0C7M7
EQDQGVSCNKVEWWW

ARID1A

2036

O14497
SSWKAWQVPWCLHDG

C22orf46

166

C9J442
WGKDSLLNKWCWENW

nan

926

O00370
AWTEGLDWCNAGWLL

HAPLN2

186

Q9GZV7
SYTCKSNWRGGWDWS

IZUMO1R

146

A6ND01
SNWRGGWDWSQGKNR

IZUMO1R

151

A6ND01
NENTEWCLAVWRGWG

LRRK1

1976

Q38SD2
ALWFNGTTDNWDQGW

ISM2

296

Q6H9L7
SGWWFCQMKAKRGWI

NCF1

191

P14598
ACDLHLWENQGAGWW

MEGF8

201

Q7Z7M0
TCKSNWHKGWNWTSG

FOLR3

151

P41439
WHKGWNWTSGINECP

FOLR3

156

P41439
SKLNFWLIQGSAWWC

DPY19L2

421

Q6NUT2
ESGWWFCQMKAKRGW

NCF1B

191

A6NI72
ESGWWFCQMKAKRGW

NCF1C

166

A8MVU1
NCPIHGKWATWASWS

HMCN1

4696

Q96RW7
GKWATWASWSACSVS

HMCN1

4701

Q96RW7
GGKWSQHDKLWLQQW

PTPRT

216

O14522
WCWAALNWLGVTVEN

HHAT

386

Q5VTY9
GVWEEVGCAKLWNEW

PSMG1

91

O95456
DTQWGWFYLAECGKW

PARP11

31

Q9NR21
SNAVDGQWGCWSSWS

C6

561

P13671
KHCSRWNWWGSTVKK

CELA3A

186

P09093
WNWWGSTVKKTMVCA

CELA3A

191

P09093
FWAIKNSWGTDWGEK

CTSF

446

Q9UBX1
CKSNWHRGWDWTSGV

FOLR2

146

P14207
EHCSRWNWWGSSVKK

CELA3B

186

P08861
WNWWGSSVKKTMVCA

CELA3B

191

P08861
TWGNAEDTWKLGRNW

CDH26

541

Q8IXH8
ETSLWDCKNWQWGGL

CD163

446

Q86VB7
GQVEWNGSWSDRWKD

CAPN3

361

P20807
GWKWTLNSGKAREWT

PPP1R18

331

Q6NYC8
CWDGWNGNACEIWLG

ITGBL1

476

O95965
NCLGGLRNIADWWDW

PKD1L1

2326

Q8TDX9
NTPIDGKWNCWSNWS

C8B

541

P07358
GKWNCWSNWSSCSGR

C8B

546

P07358
SKLNCWLIQGSAWWC

DPY19L2P2

231

Q6ZN68
TCKSNWHKGWNWTSG

FOLR1

151

P15328
WHKGWNWTSGFNKCA

FOLR1

156

P15328
WGQLATGTNVSWCWA

PKD1

1826

P98161
DAWRGGLDWCNAGWL

HAPLN1

196

P10915
WATELPWMGCWHANS

MMP28

501

Q9H239
SHIGDWCVSRQLWWG

VARS2

516

Q5ST30
DPWSAWSASKSGNWE

SNX9

106

Q9Y5X1
GLFVGAQAWWWAFKN

TCAF1

356

Q9Y4C2
GLLIGGQAWWWASQN

TCAF2

356

A6NFQ2
SSAQKGWWFLSWFNN

GGTA1

46

Q4G0N0
DWWCENLGMWKASIT

SNX25

501

Q9H3E2
WNGKTSLDWWITDKC

SCARB2

231

Q14108
ANHWWVNWGYKSSVC

NUAK1

301

O60285
GWGHFSTVWLCWDIQ

SRPK3

86

Q9UPE1
KAGWSESLFWKLNQW

CLN8

181

Q9UBY8
WKWTNGTTFNGWFEI

CLEC2A

126

Q6UVW9
KGWCGWKGPDFWNKD

UFSP2

441

Q9NUQ7
GTEWSWKNLNTLCWA

XPO1

486

O14980
WQDCVAWALGHWKLC

UBA7

666

P41226
QSVWVKTGALQWWCD

TECPR1

606

Q7Z6L1
KTGALQWWCDWKPHK

TECPR1

611

Q7Z6L1
KLGWGHFSTVWLCWD

SRPK2

86

P78362
WWLQGHVEECQATSW

TEX13C

91

A0A0J9YWL9
VNGGWSSWTEWSACN

UNC5D

251

Q6UXZ4
KISWGQGHFWELWRS

WDR6

96

Q9NNW5
WRECWVAGWGQTNAA

PRSS55

186

Q6UWB4
WNWAFGVCNKYWKGT

TRIM49D1

351

C9J1S8
FWIAANSWGKSWGEN

TINAG

431

Q9UJW2
WTKACEASWQWGALT

ZNF629

106

Q9UEG4
WWQAARDMEKGFCGW

TMEM169

241

Q96HH4
GNSIQKQLECWWEAW

ZBED4

781

O75132