Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

1.07e-05441335GO:0140938
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

9.05e-05681335GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

9.71e-05691335GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

1.11e-04711335GO:0042054
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR2 ITPR3

1.32e-0431332GO:0005220
GeneOntologyMolecularFunctionprotein methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

6.31e-041031335GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

SETD1A MECOM PRDM2 SETBP1 DOT1L

6.89e-041051335GO:0008170
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

SETD1A CAD MECOM PRDM2 PRDM10 SETBP1 DOT1L

7.66e-042241337GO:0016741
GeneOntologyMolecularFunctionhistone modifying activity

SETD1A KAT6A MECOM PRDM2 SETBP1 DOT1L HR

8.72e-042291337GO:0140993
MousePhenointervertebral disk degeneration

MECOM NFIX TP63

9.32e-0661103MP:0004684
DomainEGF

FRAS1 BRINP3 CNTNAP5 CELSR2 SUSD1 VCAN TENM1 NID1 MUC3A

4.24e-052351319SM00181
DomainDUF3697_Uba2

UBAP2 UBAP2L

4.88e-0521312IPR022166
DomainDUF3697

UBAP2 UBAP2L

4.88e-0521312PF12478
DomainEGF-like_dom

FRAS1 CNTNAP5 HMCN2 CELSR2 SUSD1 VCAN TENM1 NID1 MUC3A

6.63e-052491319IPR000742
DomainEGF_1

CNTNAP5 HMCN2 CELSR2 SUSD1 VCAN TENM1 NID1 USH2A MUC3A

7.96e-052551319PS00022
DomainInsP3_rcpt-bd

ITPR2 ITPR3

1.46e-0431312IPR000493
DomainAT_hook

ZBTB24 SETBP1 DOT1L

1.77e-04161313PF02178
DomainEGF_3

CNTNAP5 HMCN2 CELSR2 SUSD1 VCAN TENM1 NID1 MUC3A

2.56e-042351318PS50026
DomainG2F

HMCN2 NID1

2.90e-0441312PF07474
DomainNIDOGEN_G2

HMCN2 NID1

2.90e-0441312PS50993
DomainGFP

HMCN2 NID1

2.90e-0441312IPR009017
DomainG2_nidogen/fibulin_G2F

HMCN2 NID1

2.90e-0441312IPR006605
Domain-

ADGRG4 CNTNAP5 CELSR2 WDFY3 USH2A

5.50e-049513152.60.120.200
DomainEGF_2

CNTNAP5 HMCN2 CELSR2 SUSD1 VCAN TENM1 NID1 MUC3A

5.69e-042651318PS01186
DomainASX_HYDROXYL

HMCN2 CELSR2 SUSD1 VCAN NID1

6.95e-041001315PS00010
DomainRIH_assoc-dom

ITPR2 ITPR3

7.19e-0461312IPR013662
DomainIns145_P3_rec

ITPR2 ITPR3

7.19e-0461312PF08709
DomainRIH_assoc

ITPR2 ITPR3

7.19e-0461312PF08454
DomainRIH_dom

ITPR2 ITPR3

7.19e-0461312IPR000699
DomainIns145_P3_rcpt

ITPR2 ITPR3

7.19e-0461312IPR014821
DomainRyanodine_recept-rel

ITPR2 ITPR3

7.19e-0461312IPR015925
Domain-

ITPR2 ITPR3

7.19e-04613121.25.10.30
DomainRYDR_ITPR

ITPR2 ITPR3

7.19e-0461312PF01365
DomainGrowth_fac_rcpt_

FRAS1 BRINP3 HMCN2 CELSR2 SUSD1 NID1

8.17e-041561316IPR009030
DomainAT_hook

ZBTB24 SETBP1 DOT1L

8.72e-04271313SM00384
DomainAT_hook_DNA-bd_motif

ZBTB24 SETBP1 DOT1L

8.72e-04271313IPR017956
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN2 CELSR2 SUSD1 VCAN NID1

9.05e-041061315IPR000152
DomainHMGI/Y_DNA-bd_CS

ZBTB24 SETBP1 DOT1L

1.31e-03311313IPR000637
DomainEGF_CA

HMCN2 CELSR2 SUSD1 VCAN NID1

1.69e-031221315SM00179
DomainEGF-like_Ca-bd_dom

HMCN2 CELSR2 SUSD1 VCAN NID1

1.82e-031241315IPR001881
DomainMIR

ITPR2 ITPR3

2.12e-03101312PF02815
DomainMIR_motif

ITPR2 ITPR3

2.12e-03101312IPR016093
DomainMIR

ITPR2 ITPR3

2.12e-03101312PS50919
DomainMIR

ITPR2 ITPR3

2.12e-03101312SM00472
DomainLAM_G_DOMAIN

CNTNAP5 CELSR2 USH2A

2.38e-03381313PS50025
DomainEGF-like_CS

HMCN2 CELSR2 SUSD1 VCAN TENM1 NID1 MUC3A

2.47e-032611317IPR013032
DomainGFP-like

SUSD1 NID1

2.58e-03111312IPR023413
Domain-

SUSD1 NID1

2.58e-031113122.40.155.10
DomainLaminin_G_2

CNTNAP5 CELSR2 USH2A

2.76e-03401313PF02210
Domain-

MARF1 GEN1

3.08e-031213123.40.50.1010
DomainLamG

CNTNAP5 CELSR2 USH2A

3.62e-03441313SM00282
DomainSEA

MUC16 MUC3A

4.20e-03141312SM00200
DomainPIN_domain-like

MARF1 GEN1

4.20e-03141312IPR029060
DomainPI3/4_kinase_CS

SMG1 PIK3C2G

4.83e-03151312IPR018936
DomainEGF_Ca-bd_CS

HMCN2 SUSD1 VCAN NID1

4.84e-03971314IPR018097
DomainSET_dom

SETD1A PRDM2 PRDM10

5.20e-03501313IPR001214
DomainSET

SETD1A PRDM2 PRDM10

5.20e-03501313PS50280
DomainEGF_CA

HMCN2 SUSD1 VCAN NID1

5.21e-03991314PS01187
Domain-

SMG1 PIK3C2G

5.49e-031613121.10.1070.11
DomainPI3Kc

SMG1 PIK3C2G

5.49e-03161312SM00146
DomainPI3_PI4_kinase

SMG1 PIK3C2G

6.94e-03181312PF00454
DomainPI3_4_KINASE_1

SMG1 PIK3C2G

6.94e-03181312PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3C2G

6.94e-03181312PS00916
DomainPI3/4_kinase_cat_dom

SMG1 PIK3C2G

6.94e-03181312IPR000403
DomainPI3_4_KINASE_3

SMG1 PIK3C2G

6.94e-03181312PS50290
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A CAD UBAP2 MAP4 BAG3 MED1 PHGDH LUZP1 UBAP2L LPP XRN1 NUMB CLINT1 DOT1L SAP130 RPAP2

4.91e-105491351638280479
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

ATMIN SMG1 MBNL1 ZBTB24 HSPA12A SETBP1 MARF1

1.31e-095213579455477
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DMTF1 SETD1A UBAP2 NUP214 MLLT10 POM121 KLF5 TP63 SETBP1 NUMB CLINT1 SAP130 SOS1

1.47e-084301351335044719
Pubmed

Human transcription factor protein interaction networks.

FLG SMG1 SETD1A CAD UBAP2 MBNL1 HIPK2 MECOM NUP214 MLLT10 PRDM2 FHAD1 UBAP2L NFIX KLF5 SVIL EPC1 XRN1 MARF1 DOT1L SAP130 FBXW7

3.41e-0814291352235140242
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

DMTF1 MAP4 MAP4K3 ARHGAP26 MBNL1 HIPK2 DAG1 ANKRD50 ZBTB24 E2F8 PRDM2 UBAP2L VCAN LPP CEP295 DOT1L GEN1 PCDH18 BRWD1

4.41e-0810841351911544199
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DENND4A UBAP2 MAP4 CEP85L ZCCHC8 BAG3 MLXIP E2F8 LUZP1 SVIL LPP XRN1 NUMB AKAP11 CLINT1 LIMCH1 GEN1

4.45e-088611351736931259
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

UBAP2 MAP4 BAG3 DAG1 NUP214 LUZP1 SVIL LPP VSIG10L XRN1 NUMB CLINT1 LIMCH1 ACBD3

4.80e-085651351425468996
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

UBAP2 MAP4 NUP214 LUZP1 UBAP2L XRN1 ASPM CLINT1 LIMCH1 KNL1

6.89e-082561351033397691
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 SETD1A CAD UBAP2 NUP214 MED1 ITPR2 ITPR3 POM121 UBAP2L ASCC2 RPAP2

1.65e-074401351234244565
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

MAP4 BAG3 SPART NUP214 LUZP1 ITPR3 UBAP2L ATP6AP2 XRN1 TACC1 CLINT1 LIMCH1 ACBD3

3.65e-075681351337774976
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

UBAP2 MAP4 ZCCHC8 BAG3 SPART NUP214 MED1 PHGDH UBAP2L LPP XRN1 NUMB TACC1 CLINT1 ACBD3 KNL1

7.55e-079341351633916271
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATMIN SETD1A FRAS1 ARHGAP26 KAT6A KSR2 NUP214 MLLT10 MLXIP ITPR2 ITPR3 RPAP1 CELSR2 DISP2 WDFY3 DOT1L HR

1.45e-0611051351735748872
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

PDPN KLF5 TP63 FBXW7

1.50e-0622135434998785
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

SMG1 UBAP2 ARHGAP26 AGGF1 MUC16 MLXIP PRDM2 EPC1 TENM1 ZFHX2 AKAP11 MUC3A

1.79e-065521351210737800
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

ZCCHC8 CCDC28A SNUPN MLXIP ANKRD50 PHGDH WDR45 RPAP1 UBAP2L KLF5 LPP XRN1 NUMB CLINT1 LIMCH1 RPAP2

2.95e-0610381351626673895
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

POLA1 SPART NUP214 UBAP2L EPC1 XRN1 AKAP11 KNL1

5.07e-06242135834011540
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

UBAP2 MAP4 POLA1 MBNL1 SPART MED1 LUZP1 UBAP2L XRN1 MARF1 ASCC2 CLINT1 GEN1

5.29e-067241351336232890
Pubmed

Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.

FRAS1 PDPN NID1

6.73e-0610135315623520
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

ZCCHC8 POLA1 MBNL1 BAG3 DAG1 SPART NUP214 LUZP1 POM121 LPP NUMB TACC1 CLINT1 ACBD3 RPAP2

9.21e-0610071351534597346
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

POM121 SVIL LPP XRN1 TENM1 NUMB TACC1 ACBD3

9.31e-06263135834702444
Pubmed

rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.

MBNL1 RBFOX1

1.50e-052135229789616
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

1.50e-05213529065779
Pubmed

hDOT1L links histone methylation to leukemogenesis.

MLLT10 DOT1L

1.50e-052135215851025
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

1.50e-05213528081734
Pubmed

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

MLLT10 DOT1L

1.50e-052135219443658
Pubmed

The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis.

NUMB ACBD3

1.50e-052135217418793
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

1.50e-052135215632133
Pubmed

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

HIPK2 TP63

1.50e-052135221602882
Pubmed

UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.

UBAP2 UBAP2L

1.50e-052135235633597
Pubmed

lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a set of novel cytoplasmic proteins.

UBAP2 UBAP2L

1.50e-052135212524348
Pubmed

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.

CDH23 USH2A

1.50e-052135217360538
Pubmed

AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.

MLLT10 DOT1L

1.50e-052135234215314
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

1.50e-052135217496801
Pubmed

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.

MLLT10 DOT1L

1.50e-052135225464900
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

1.50e-052135224901844
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

1.50e-052135233854148
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

1.50e-052135219528657
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

1.50e-05213528063813
Pubmed

C-Terminal region of teneurin-1 co-localizes with dystroglycan and modulates cytoskeletal organization through an extracellular signal-regulated kinase-dependent stathmin- and filamin A-mediated mechanism in hippocampal cells.

DAG1 TENM1

1.50e-052135222698694
Pubmed

A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.

CEP85L ITPR2

1.50e-052135222010048
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

1.50e-052135216195467
Pubmed

FBXW7 loss of function promotes esophageal squamous cell carcinoma progression via elevating MAP4 and ERK phosphorylation.

MAP4 FBXW7

1.50e-052135236991467
Pubmed

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

MBNL1 RBFOX1

1.50e-052135225211016
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

1.50e-052135215713744
Pubmed

DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral cancer in patients with leukoplakia.

PDPN TP63

1.50e-052135219773378
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

ATMIN CAD MAP4 KAT6A DOCK10 NUP214 PRDM10 HMCN2

1.58e-05283135818854154
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

CAD POLA1 NUP214 SNUPN PHGDH PRDM2 RPAP1 UBAP2L

1.62e-05284135829459677
Pubmed

Functional proteomics mapping of a human signaling pathway.

THAP5 DMTF1 SMG1 ZCCHC8 SPART SUSD1 ASCC2 NID1 ACBD3 SAP130 KNL1

2.08e-055911351115231748
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

UBAP2 BAG3 SPART WDR45 XRN1 CLINT1 LIMCH1

2.28e-05216135731519766
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DENND4A ANKRD50 ITPR2 ITPR3 WDR45 ATP6AP2 TENM1 AKAP11 TACC1 ACBD3

2.93e-055041351034432599
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZCCHC8 KAT6A MECOM LUZP1 HMCN2 EPC1 XRN1 ASPM CEP295 WDFY3 SAP130 KNL1 SOS1 BRWD1 RPAP2

3.04e-0511161351531753913
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

CAD UBAP2 SPART MED1 UBAP2L RPAP2

3.21e-05154135616055720
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATMIN FRAS1 DOCK10 NUP214 MLXIP RPAP1 UBAP2L DISP2 LIMCH1

3.22e-05407135912693553
Pubmed

Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.

ZNF280B PDPN EPC1 TNFRSF19 FBXW7

3.23e-059313557829101
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FRAS1 CAD MAP4 E2F8 ATP6AP2 SETBP1 XRN1 TENM1 NID1 TNFRSF19

3.40e-055131351025798074
Pubmed

Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.

CDH23 PMEL LPP

3.74e-0517135322951725
Pubmed

CEBPA-Associated Familial Acute Myeloid Leukemia (AML)

NUP214 MLLT10 LPP

3.74e-0517135320963938
Pubmed

ETV6 Thrombocytopenia and Predisposition to Leukemia

NUP214 MLLT10 LPP

3.74e-0517135333226740
Pubmed

RUNX1 Familial Platelet Disorder with Associated Myeloid Malignancies

NUP214 MLLT10 LPP

3.74e-0517135333661592
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MAP4K3 CCDC28A DAG1 ANKRD50 ERICH5 HSPA12A CELSR2 NUMB ACBD3

4.18e-05421135936976175
Pubmed

DDX41-Associated Familial Myelodysplastic Syndrome and Acute Myeloid Leukemia

NUP214 MLLT10 LPP

4.47e-0518135334723452
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR2 ITPR3

4.48e-053135210874040
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR2 ITPR3

4.48e-053135220395455
Pubmed

Role of CD10, wide-spectrum keratin, p63, and podoplanin in the distinction of epithelioid and spindle cell tumors of the skin: an immunohistochemical study of 81 cases.

PDPN TP63

4.48e-053135222257901
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR2 ITPR3

4.48e-053135217437169
Pubmed

Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration.

KLF5 TP63

4.48e-053135232081850
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR2 ITPR3

4.48e-053135218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR2 ITPR3

4.48e-053135236350267
Pubmed

The versatility and universality of calcium signalling.

ITPR2 ITPR3

4.48e-053135211413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

4.48e-053135226009177
Pubmed

Regulation of adipocyte differentiation by clusterin-mediated Krüppel-like factor 5 stabilization.

KLF5 FBXW7

4.48e-053135233078455
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR2 ITPR3

4.48e-05313521693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR2 ITPR3

4.48e-053135223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR2 ITPR3

4.48e-053135231979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR2 ITPR3

4.48e-053135224904548
Pubmed

Deletion of the prorenin receptor in the ureteric bud in mice inhibits Dot1/H3K79 pathway.

ATP6AP2 DOT1L

4.48e-053135238287105
Pubmed

TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines.

KLF5 TP63

4.48e-053135232619460
Pubmed

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.

KLF5 TP63

4.48e-053135234272396
Pubmed

POMT1 is essential for protein O-mannosylation in mammals.

DAG1 NID1

4.48e-053135220816174
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR2 ITPR3

4.48e-05313529858485
Pubmed

A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).

KLF5 FBXW7

4.48e-053135224398687
Pubmed

Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.

ITPR2 ITPR3

4.48e-053135221435446
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR2 ITPR3

4.48e-05313529808793
Pubmed

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.

ASPM FBXW7

4.48e-053135238279565
Pubmed

The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis.

MLLT10 DOT1L

4.48e-053135237082953
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR2 ITPR3

4.48e-053135218194433
Pubmed

Persistent stromal fibroblast activation is present in chronic tendinopathy.

PDPN VCAM1

4.48e-053135228122639
Pubmed

D2-40: an additional marker for myoepithelial cells of breast and the precaution in interpreting tumor lymphovascular invasion.

PDPN TP63

4.48e-053135221326813
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR2 ITPR3

4.48e-053135227777977
Pubmed

The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.

KLF5 FBXW7

4.48e-053135220388706
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR2 ITPR3

4.48e-053135217581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR2 ITPR3

4.48e-053135218241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR2 ITPR3

4.48e-053135219068129
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

4.48e-053135217327232
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR2 ITPR3

4.48e-053135216014380
Pubmed

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

MECOM SETBP1

4.48e-053135216582916
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR2 ITPR3

4.48e-053135217890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR2 ITPR3

4.48e-053135223983250
Pubmed

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation.

TP63 FBXW7

4.48e-053135220571051
Pubmed

Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.

BRINP3 VCAM1

4.48e-053135225251368
InteractionG3BP1 interactions

CAD ARHGAP24 UBAP2 MAP4 MAP4K3 BAG3 NUP214 ITGA2B LUZP1 UBAP2L KLF5 LPP RBFOX1 DOT1L ACBD3 SAP130 VCAM1 FBXW7 RPAP2

2.18e-0683513219int:G3BP1
InteractionMYH9 interactions

DENND4A CAD ARHGAP24 GRIA4 LUZP1 ITPR2 ITPR3 PTP4A3 TP63 SVIL ASCC2 CLINT1 LIMCH1 DOT1L ACBD3 VCAM1 FBXW7

8.87e-0675413217int:MYH9
InteractionVIM interactions

CAD ARHGAP24 MBNL1 BAG3 DOCK10 SPART GRIA4 ITGA2B PHGDH LUZP1 ATP6AP2 NFIX SVIL LPP NUMB VCAM1 RPAP2

2.03e-0580413217int:VIM
InteractionTJP2 interactions

MBNL1 ANKRD50 LUZP1 PTP4A3 SVIL LPP LIMCH1 ACBD3 FBXW7 RPAP2

2.05e-0528813210int:TJP2
InteractionTOP3B interactions

ATMIN SETD1A FRAS1 CAD UBAP2 ARHGAP26 KAT6A KSR2 NUP214 MLLT10 MLXIP PHGDH ITPR2 ITPR3 RPAP1 CELSR2 UBAP2L ATP6AP2 SVIL XRN1 DISP2 WDFY3 DOT1L HR

2.73e-05147013224int:TOP3B
InteractionVCL interactions

ARHGAP24 DAG1 NFIX TP63 SVIL LPP ASCC2 VCAM1 KNL1 RPAP2

3.34e-0530513210int:VCL
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A MECOM PRDM2 DOT1L

1.64e-0534824487
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

MECOM PRDM2 PRDM10

5.84e-05178231197
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR2 ITPR3

6.08e-053822297
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ITGA2B ITPR3 MARF1 AKAP11 KNL1

1.39e-03181825694
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP24 ARHGAP26 ARHGAP20

1.51e-0350823721
CoexpressionSHEN_SMARCA2_TARGETS_UP

ATMIN GIN1 MAP4K3 MFSD6 AGGF1 ATP6AP2 MARF1 NUMB AKAP11 CLINT1 LIMCH1 WDFY3

2.21e-0642913412M29
CoexpressionLAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE

FRAS1 ARHGAP24 MAP4K3 MECOM PIK3C2G SVIL TACC1 LIMCH1

1.22e-052081348M39233
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

KANSL1L MAP4K3 MBNL1 HIPK2 ITPR2 SETBP1 LIMCH1

1.36e-051521347M39239
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DMTF1 SMG1 DENND4A CEP85L STK17B KAT6A MBNL1 DOCK10 AGGF1 MED1 LUZP1 PRDM2 ITPR2 ATP6AP2 EPC1 XRN1 AKAP11 TACC1 TMEM123 SOS1 BRWD1

2.28e-05149213421M40023
CoexpressionLAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE

KANSL1L FRAS1 MAP4K3 MECOM PIK3C2G SETBP1 LIMCH1

2.91e-051711347M39234
CoexpressionLIM_MAMMARY_STEM_CELL_UP

ARHGAP24 MBNL1 BAG3 DOCK10 LUZP1 PDPN TP63 VCAN TACC1 ARHGAP20 PCDH18

3.70e-0547913411M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

ARHGAP24 MBNL1 BAG3 DOCK10 LUZP1 PDPN TP63 VCAN TACC1 ARHGAP20 PCDH18

3.99e-0548313411MM1082
CoexpressionLIAO_HAVE_SOX4_BINDING_SITES

UBAP2 MAP4 UBAP2L VCAN

5.71e-05411344M15025
CoexpressionGSE25087_TREG_VS_TCONV_ADULT_DN

CAD BAG3 HIPK2 ZNF280B ZBTB26 ANKRD50 SVIL

6.70e-051951347M4652
CoexpressionPYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP

POLA1 CCDC150 MECOM E2F8 GEN1 KNL1 BRWD1

6.70e-051951347M13736
CoexpressionGSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP

SETD1A HIPK2 MLXIP RGS18 SUSD1 UBAP2L

6.70e-051341346M430
CoexpressionGSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_DN

UBAP2 AGGF1 PRDM10 SAP130 PARM1 KNL1 SOS1

7.38e-051981347M7267
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

ARHGAP26 MBNL1 HIPK2 SVIL TACC1 LIMCH1

7.58e-051371346M39241
CoexpressionGSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN

DAG1 ITPR2 RPAP1 CELSR2 KLF5 TP63 SVIL

7.61e-051991347M7319
CoexpressionGSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP

MAP4 MAP4K3 ITPR2 IGHM EPC1 XRN1 ASPM

7.86e-052001347M3428
CoexpressionCUI_TCF21_TARGETS_2_UP

FRAS1 CAD PHGDH NFIX KLF5 VCAN ASPM VCAM1 PARM1 KNL1

8.69e-0543713410M1610
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

CAD MAP4 DAG1 ITPR3 HSPA12A CELSR2 UBAP2L VCAN

9.06e-052761348M3063
CoexpressionCUI_TCF21_TARGETS_2_UP

FRAS1 CAD PHGDH NFIX KLF5 VCAN ASPM VCAM1 PARM1 KNL1

1.21e-0445513410MM1189
CoexpressionMARTINEZ_RESPONSE_TO_TRABECTEDIN

POLA1 LPP MARF1 NUMB

1.25e-04501344M5077
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

ARHGAP24 POLA1 FKBP9 MUC16 GRIA4 ANKRD50 E2F8 PDPN HSPA12A NFIX VCAN SVIL ASPM NID1 ARHGAP20 GEN1 PCDH18 VCAM1

1.45e-0677313218gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FRAS1 ARHGAP24 SPART MUC16 GRIA4 E2F8 HSPA12A NFIX VCAN SVIL LPP NID1 ARHGAP20 GEN1 PCDH18 VCAM1 PARM1 KNL1

1.56e-0677713218gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

FRAS1 ARHGAP24 HIPK2 MECOM E2F8 HSPA12A CELSR2 SUSD1 NFIX VCAN RBFOX1 ASPM CLINT1 GEN1 VCAM1 KNL1

2.93e-0578313216gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FKBP9 DOCK10 SPART MUC16 GRIA4 E2F8 HSPA12A VCAN SVIL ASPM NID1 ARHGAP20 GEN1 PCDH18 VCAM1 KNL1

3.41e-0579313216gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

SMG1 SETD1A MAP4 LPP ASPM CEP295 WDFY3 ARHGAP20 KNL1

3.58e-052591329gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

POLA1 FKBP9 MECOM E2F8 RGS18 SUSD1 SETBP1 ASPM WDFY3 GEN1 KNL1

6.88e-0542313211GSM791126_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

POLA1 FKBP9 DOCK10 MUC16 GRIA4 ANKRD50 PDPN HSPA12A VCAN SVIL ASPM NID1 ARHGAP20 PCDH18 VCAM1

8.77e-0576813215gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

CEP85L MAP4K3 ARHGAP26 DOCK10 MECOM ANKRD50 LUZP1 HSPA12A NFIX SETBP1 LPP NID1 CD302 TACC1 PCDH18 VCAM1

1.04e-0487213216gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

GIN1 POLA1 MECOM LUZP1 CELSR2 PTPRZ1 KLF5 SETBP1 ASPM ZFHX2 TNFRSF19 CEP295 TMEM123 GEN1 KNL1 FBXW7 BRWD1

1.38e-0498913217Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

GIN1 POLA1 MECOM LUZP1 SETBP1 ASPM CEP295 GEN1 KNL1

1.45e-043111329Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500

SETD1A MAP4 LPP CEP295 WDFY3 ARHGAP20

2.09e-041361326gudmap_developingGonad_P2_epididymis_500_k2
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

DENND4A BAG3 FKBP9 MUC16 ITPR2 NFIX VCAN RBFOX1 NUMB MANSC4 AKAP11 TNFRSF19 ARHGAP20 PCDH18

2.12e-0474013214gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasStem Cells, SC.ST34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34+, Bone marrow, avg-2

POLA1 FKBP9 MECOM ITGA2B RGS18 SUSD1 NFIX ASPM WDFY3 KNL1

2.54e-0441113210GSM791112_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

POLA1 MFSD6 MECOM LUZP1 PDPN CELSR2 PTPRZ1 SETBP1 ASPM TMEM123 FBXW7

2.62e-0449313211Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4

KAT6A UBAP2L NUMB WDFY3 ACBD3 SOS1 BRWD1

2.83e-042031327Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlasStem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2

POLA1 FKBP9 MECOM ITGA2B E2F8 RGS18 SUSD1 NFIX WDFY3 KNL1

3.13e-0442213210GSM399442_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

SETD1A GIN1 DAG1 FETUB ITPR2 UBAP2L NFIX TP63 LPP MARF1 NID1 TNFRSF19 CEP295 WDFY3

3.17e-0477013214gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#2_top-relative-expression-ranked_1000

DOCK10 MECOM ANKRD50 SETBP1 LPP NID1 TACC1 PCDH18 VCAM1

3.33e-043481329gudmap_kidney_adult_Mesangium_Meis_k2_1000
CoexpressionAtlasB cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3

DENND4A ARHGAP24 ARHGAP26 ITPR3 PTP4A3 RGS18 SUSD1 TMEM123 BRWD1

3.33e-043481329GSM538216_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

DMTF1 SMG1 KAT6A PRDM2 CELSR2 PTPRZ1 NUMB CEP295 WDFY3 ACBD3 SAP130 SOS1

3.45e-0459513212Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

FRAS1 DENND4A STK17B MBNL1 DOCK10 MUC16 GRIA4 PDPN PTPRZ1 NFIX KLF5 SVIL NID1 CD302

3.52e-0477813214gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

SETD1A MAP4 LPP ASPM CEP295 WDFY3

3.54e-041501326gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

BAG3 FKBP9 PDPN NFIX VCAN NID1 CD302 ARHGAP20 PCDH18 VCAM1

4.12e-0443713210GSM777046_500
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

SMG1 MED1 LUZP1 PRDM10 LPP MARF1 CEP295 SAP130 SOS1

6.19e-09186136903db813598b67b1e08f759758a1c2023396921fa
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MAP4K3 ARHGAP26 MECOM ITPR2 LPP LIMCH1 WDFY3 FBXW7 SOS1

1.11e-08199136994b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA3 BRINP3 KSR2 MECOM GRIA4 SUSD1 PIK3C2G LIMCH1

1.77e-081471368b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4 KSR2 DOCK10 MECOM SUSD1 PIK3C2G LIMCH1

8.54e-081801368023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 DENND4A CEP85L ARHGAP26 MBNL1 DOCK10 PRDM2 LPP

1.19e-071881368ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM CNTNAP5 SUSD1 PIK3C2G LIMCH1

1.19e-07188136858ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 MECOM SUSD1 PIK3C2G SETBP1 TNFRSF19 LIMCH1

1.29e-0719013684836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP24 PDPN NFIX VCAN XRN1 NID1 CD302 ARHGAP20

1.35e-0719113687d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A ARHGAP24 PRDM2 IGHM SETBP1 GEN1 KNL1 PARP15

1.58e-071951368481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A ARHGAP24 PRDM2 IGHM SETBP1 GEN1 KNL1 PARP15

1.58e-0719513686108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BAG3 FKBP9 PDPN NFIX VCAN NID1 CD302 VCAM1

1.58e-071951368773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1L ARHGAP24 MAP4K3 MECOM LPP LIMCH1 FBXW7 SOS1

1.64e-071961368ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellCOVID-19|World / Disease, condition lineage and cell class

STK17B MBNL1 PRDM2 EPC1 XRN1 TACC1 CLINT1 TMEM123

1.92e-0720013687dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 BAG3 DOCK10 PTPRZ1 SVIL LIMCH1 PCDH18

3.87e-07149136710ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DENND4A ARHGAP24 STK17B KAT6A MBNL1 PRDM2 IGHM

9.05e-071691367c3a6179a64589a370108fea809b157839347759c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 KSR2 MECOM PIK3C2G TNFRSF19 LIMCH1

1.33e-061791367666072c0e8448dbaec1683d18368ec2502453f90
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 ARHGAP26 KAT6A DOCK10 CLEC7A XRN1 CLINT1

1.48e-061821367f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 KSR2 MECOM SUSD1 PIK3C2G LIMCH1

1.48e-061821367f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ITGA2B PHGDH PDPN HSPA12A KLF5 PARM1

1.60e-061841367e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L FRAS1 KSR2 MECOM SUSD1 PIK3C2G LIMCH1

1.66e-061851367d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 MECOM SUSD1 PIK3C2G SETBP1 LIMCH1

1.72e-06186136708632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 CEP85L KAT6A HIPK2 LUZP1 PTP4A3 NUMB

1.78e-061871367ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP4 PHGDH ITPR2 KLF5 TP63 TNFRSF19 LIMCH1

1.78e-0618713679c1013720c248ef201d010806b6e7ad24205e8ee
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DAG1 PHGDH PDPN HSPA12A KLF5 PARM1

1.78e-061871367806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM SUSD1 PIK3C2G LIMCH1

1.78e-061871367e3095455d2f255854f339f6b05fa87852af0700f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 MECOM SUSD1 PIK3C2G SETBP1 LIMCH1

1.91e-0618913678ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 MECOM SUSD1 PIK3C2G TNFRSF19 LIMCH1

1.91e-06189136790aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM SUSD1 PIK3C2G LIMCH1

1.91e-061891367c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

ARHGAP26 HIPK2 MECOM ITPR2 VCAN SETBP1 TACC1

1.91e-06189136775c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ARHGAP26 HIPK2 MECOM ITPR2 SETBP1 NUMB TACC1

1.91e-061891367c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 DAG1 PDPN FHAD1 KLF5 VCAM1 PARM1

1.91e-061891367319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRABD2A TRAV6 STK17B DOCK10 CD226 TENM1 TMEM123

1.98e-0619013672a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMTF1 STK17B MBNL1 DOCK10 CD226 XRN1 PARP15

1.98e-061901367d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 KSR2 MECOM CNTNAP5 SUSD1 PIK3C2G LIMCH1

1.98e-061901367b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 DAG1 PDPN FHAD1 KLF5 VCAM1 PARM1

1.98e-061901367050d6e0546954675b6adbfecb67854b1e09739d1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A CEP85L STK17B MBNL1 DOCK10 CD226 PARP15

1.98e-06190136707ea0578ca0561077557203ae660530f53fc4067
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A CEP85L STK17B MBNL1 DOCK10 CD226 PARP15

1.98e-0619013675b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A CEP85L STK17B MBNL1 DOCK10 CD226 PARP15

2.05e-061911367d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A CEP85L STK17B MBNL1 DOCK10 CD226 PARP15

2.05e-061911367b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP24 MECOM ITPR3 KLF5 SVIL RBFOX1 CLINT1

2.05e-0619113675a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP24 MECOM ITPR3 KLF5 SVIL RBFOX1 CLINT1

2.05e-06191136755ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 BAG3 NFIX KLF5 VCAM1 PARM1 HR

2.05e-0619113678691eba35793e4e90f93d50c2145847ee51289f7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2A CEP85L STK17B MBNL1 DOCK10 CD226 PARP15

2.05e-0619113679aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

DENND4A ARHGAP24 PRDM2 SETBP1 AKAP11 GEN1 PARP15

2.19e-0619313677ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 MBNL1 ITPR2 VCAN TNFRSF19 TACC1 SOS1

2.19e-061931367e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A ARHGAP24 PRDM2 IGHM SETBP1 GEN1 PARP15

2.27e-0619413675cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM CELSR2 PIK3C2G KLF5

2.27e-061941367be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC7A RGS18 CELSR2 CD226 VCAM1 PARM1 HR

2.27e-0619413675a048bd2af30975fdc57ff40bc49aa5811c830d8
ToppCell11.5-Distal-Epithelial-Bud_tip_progenitor|Distal / Age, Tissue, Lineage and Cell class

TRABD2A ERICH5 E2F8 ITPR3 PIK3C2G PTPRZ1 PARM1

2.43e-06196136742eae265e2f2082983d8c2607c7f6a53a526d124
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MAP4 MBNL1 FKBP9 DAG1 LPP TMEM123

2.43e-061961367151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP24 DOCK10 RBFOX1 NID1 TACC1 PCDH18 VCAM1

2.60e-06198136772aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1L ARHGAP24 MAP4K3 MECOM LPP LIMCH1 WDFY3

2.60e-0619813671996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellfacs-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BAG3 FKBP9 PDPN NFIX VCAN NID1 CD302

2.60e-061981367e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STK17B CLEC7A NUP214 CACNA2D4 RGS18 VCAN CD302

2.60e-0619813676d547122b8c4ddbdd0d3dae3bce4a125740d5457
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FRAS1 MUC16 GRIA4 PHGDH PDPN RBFOX1 VCAM1

2.69e-0619913678dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDPN VCAN NID1 CD302 LIMCH1 ARHGAP20 VCAM1

2.69e-061991367a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

VCAN NID1 CD302 LIMCH1 ARHGAP20 PCDH18 VCAM1

2.69e-06199136730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC|2m / Sample Type, Dataset, Time_group, and Cell type.

PTPRZ1 NFIX SETBP1 TMEM123 PCDH18 VCAM1 FBXW7

2.78e-0620013673c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related|2m / Sample Type, Dataset, Time_group, and Cell type.

PTPRZ1 NFIX SETBP1 TMEM123 PCDH18 VCAM1 FBXW7

2.78e-0620013678e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCellSigmoid-(4)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

CLEC7A RGS18 SUSD1 VCAN NID1 CD302 WDFY3

2.78e-0620013677f3920a0434d5199c6c8f0b3064a305bb0d87b60
ToppCellSigmoid-Monocyte-Monocyte|Sigmoid / Region, Cell class and subclass

CLEC7A RGS18 SUSD1 VCAN NID1 CD302 WDFY3

2.78e-062001367010ca36970cb8894bdbca08779c0ecf56be22fc9
ToppCellSigmoid-Monocyte|Sigmoid / Region, Cell class and subclass

CLEC7A RGS18 SUSD1 VCAN NID1 CD302 WDFY3

2.78e-062001367c41bd6ec0f2262fce5cadb37a400d487e6662f49
ToppCellSigmoid-(4)_Monocyte-(40)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

CLEC7A RGS18 SUSD1 VCAN NID1 CD302 WDFY3

2.78e-062001367576c0a1098e6a934448705de3673ef798fcf1b26
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Glia_progenitor_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

CEP85L SPART PHGDH PDPN PTPRZ1 LIMCH1 TMEM123

2.78e-0620013674859fbe663ae9372fc8ed3b4e1fa301e06621a31
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PMEL E2F8 ITPR2 PDPN PTPRZ1 VCAN

3.42e-06133136663d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 ARHGAP24 DOCK10 PTPRZ1 LIMCH1 PCDH18

5.40e-0614413667de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGAP24 DOCK10 PTPRZ1 VCAN PCDH18 PARM1

7.37e-0615213668ff5a178a8f3550d89a003c0858820aab3773386
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BAG3 DOCK10 PTPRZ1 SVIL LIMCH1 PCDH18

8.24e-061551366cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ERICH5 ITPR3 CD226 IGHM ARHGAP20 PARP15

8.55e-061561366afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA3 FRAS1 GRIA4 PIK3C2G PTPRZ1 USH2A

9.88e-061601366c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA3 FRAS1 GRIA4 PIK3C2G PTPRZ1 USH2A

9.88e-06160136625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ARHGAP24 PRDM2 IGHM SETBP1 GEN1 KNL1

1.22e-0516613668de8f388f24436b84e19ef460476fdbda4d16abf
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAG1 ITGA2B HSPA12A NID1 TMEM123 VCAM1

1.22e-051661366c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 MECOM SUSD1 PIK3C2G LIMCH1 DOT1L

1.26e-051671366edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

ARHGAP24 DOCK10 PRDM2 IGHM SETBP1 PARP15

1.30e-051681366a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

E2F8 VCAN ASPM LIMCH1 GEN1 KNL1

1.35e-051691366563c267edaade0e5df192ad953801ef9768d4270
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 ARHGAP24 PTPRZ1 SVIL LIMCH1 PCDH18

1.44e-0517113665efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCell3'_v3-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

ARHGAP24 PRDM2 HSPA12A IGHM SETBP1 PARM1

1.44e-0517113669ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP24 PRDM2 IGHM SETBP1 GEN1 PARP15

1.44e-051711366a2938e56cb5749004317798dc7ac0f0c2d4d8ae0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGAP24 DOCK10 PTPRZ1 SVIL LIMCH1 PCDH18

1.49e-0517213667e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD STK17B E2F8 RGS18 SUSD1 KLF5

1.54e-05173136653e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCelldroplet-Lung-LUNG-1m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD STK17B E2F8 RGS18 SUSD1 KLF5

1.54e-051731366889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP24 PRDM2 SETBP1 GEN1 KNL1 PARP15

1.59e-051741366ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellsevere_influenza-Plasmablast|World / disease group, cell group and cell class (v2)

PHGDH E2F8 TP63 ASPM MANSC4 PARM1

1.64e-051751366e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FRAS1 DAG1 PDPN WDR45 KLF5 LIMCH1

1.70e-051761366f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 PDPN CNTNAP5 PTPRZ1 LPP PARM1

1.75e-051771366f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

ARHGAP24 STK17B PRDM2 IGHM SETBP1 PARP15

1.75e-051771366f54691e5558091c1734ab15153a10bff15ed171e
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

ARHGAP24 STK17B PRDM2 IGHM SETBP1 PARP15

1.75e-051771366653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THAP5 MFSD6 KSR2 SETBP1 RBFOX1 DOT1L

1.75e-051771366e1e45956887371b1c18f1eb479dd930031497520
ToppCell3'_v3-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

ARHGAP24 PRDM2 HSPA12A IGHM SETBP1 PARM1

1.93e-051801366237a2130a3f48595dad2417539c21e44585962b8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 KSR2 MECOM SUSD1 PIK3C2G LIMCH1

1.93e-051801366788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM SUSD1 PIK3C2G

1.99e-051811366b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

CCDC150 PHGDH VCAN ASPM CD302 KNL1

1.99e-051811366ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPA12A CELSR2 ASPM TENM1 CEP295 SAP130

2.05e-05182136639f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP24 FKBP9 CD302 TACC1 LIMCH1 VCAM1

2.05e-05182136619c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP24 IGHM SETBP1 GEN1 PARM1 PARP15

2.05e-0518213669c120ddd109103ef6fac9c32b84d16a7624d0580
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POLA1 DAG1 PMEL PIK3C2G WDFY3 DOT1L

2.12e-05183136691079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BRINP3 KSR2 MECOM PIK3C2G LIMCH1

2.12e-051831366b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MAP4K3 MECOM PIK3C2G TNFRSF19 LIMCH1

2.12e-0518313662e831a4d99c6f983793df71c0994124c943c6da9
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGAP24 PRDM2 IGHM SETBP1 PARP15 FBXW7

2.18e-051841366911658e7bb499c1bbc8419eec8ff88729bc39a75
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; PC3; HT_HG-U133A

ARHGAP24 MFSD6 DAG1 ZNF280B NUP214 MLLT10 VCAN RBFOX1 TENM1 PARM1

2.18e-07197131106335_UP
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A

MAP4 STK17B ARHGAP26 KAT6A MLLT10 VCAN ZFHX2 WDFY3 BRWD1

2.16e-0619713195746_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ZCCHC8 HIPK2 SNUPN MLLT10 E2F8 PRDM10 WDFY3 BRWD1

9.10e-0617813185086_DN
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A

MAP4 KAT6A MFSD6 MBNL1 PRDM2 ITPR2 CLINT1 WDFY3

1.41e-0518913183788_DN
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; HL60; HT_HG-U133A

MAP4 DOCK10 HIPK2 CLEC7A LUZP1 VCAN SVIL FBXW7

1.77e-0519513182336_DN
DrugLoracarbef [121961-22-6]; Down 200; 10.8uM; PC3; HT_HG-U133A

ARHGAP24 KAT6A MFSD6 HIPK2 MLLT10 KLF5 VCAN LPP

1.83e-0519613185073_DN
DrugGentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A

MAP4 ARHGAP26 MBNL1 MLLT10 VCAN SVIL NUMB SOS1

1.90e-0519713182082_DN
DrugProgesterone [57-83-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A

SPART NUP214 ITPR3 RPAP1 CD302 LIMCH1 FBXW7 SOS1

1.97e-0519813184992_DN
DrugSB 202190; Up 200; 1uM; MCF7; HT_HG-U133A

DMTF1 MAP4K3 E2F8 UBAP2L KLF5 CD302 LIMCH1 WDFY3

1.97e-0519813186909_UP
DrugPHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A

KAT6A DOCK10 ITPR2 RPAP1 KLF5 LPP WDFY3 FBXW7

1.97e-0519813186550_UP
DrugErythromycin [114-07-8]; Up 200; 5.4uM; PC3; HG-U133A

AGGF1 DAG1 SPART MLLT10 LPP NID1 LIMCH1 PARM1

1.97e-0519813181928_UP
DrugArecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A

KANSL1L DOCK10 PMEL ITPR2 ITPR3 TP63 NID1 WDFY3

2.04e-0519913185423_UP
Drugadenophostin A

ITPR2 ITPR3

3.29e-0521312ctd:C085029
DrugStrophanthidin [66-28-4]; Up 200; 9.8uM; HL60; HT_HG-U133A

STK17B ARHGAP26 KAT6A SPART PRDM10 LPP FBXW7

5.05e-0516613172525_UP
DrugThimerosal

KANSL1L MAP4 GIN1 KAT6A BAG3 HIPK2 MECOM LYSMD4 LUZP1 PRDM2 ITPR3 PTP4A3 EPC1 VSIG10L ASPM AKAP11 WDFY3 KNL1 BRWD1

5.69e-05119913119ctd:D013849
DrugStrophantine octahydrate [11018-89-6]; Up 200; 5.4uM; HL60; HT_HG-U133A

KANSL1L UBAP2 STK17B ARHGAP26 KAT6A MED1 FBXW7

6.80e-0517413171302_UP
Drugresveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

BRINP3 STK17B MLLT10 MED1 E2F8 PRDM10 ASPM

7.57e-051771317841_DN
Drugretinoic acid; Down 200; 1uM; HL60; HT_HG-U133A

MAP4 STK17B ARHGAP26 CLEC7A KLF5 VCAN NUMB

1.07e-0418713172671_DN
DrugAlsterpaullone; Down 200; 10uM; MCF7; HT_HG-U133A

BRINP3 GIN1 ZBTB24 E2F8 PRDM2 ASPM SAP130

1.07e-0418713177051_DN
DrugMethapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

MAP4 KAT6A MFSD6 AGGF1 MED1 VCAN PARM1

1.22e-0419113176644_DN
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

KAT6A NUMB CD302 TACC1 CLINT1 SOS1 RPAP2

1.30e-0419313174846_DN
DrugPrednicarbate [73771-04-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A

KAT6A AGGF1 SPART MECOM PTP4A3 TACC1 FBXW7

1.34e-0419413175544_DN
DrugMenadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A

DOCK10 HIPK2 AGGF1 MLLT10 AKAP11 WDFY3 BRWD1

1.34e-0419413174662_DN
DrugF0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A

BRINP3 PMEL PRDM2 ITPR2 PTP4A3 KLF5 LIMCH1

1.38e-0419513176424_DN
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; HL60; HG-U133A

DENND4A MAP4 ZCCHC8 SPART MED1 LUZP1 PTP4A3

1.38e-0419513172006_DN
DrugNiclosamide [50-65-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

BRINP3 AGGF1 MECOM PRDM2 RPAP1 CD302 TACC1

1.38e-0419513171498_DN
Drug16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

MAP4K3 MBNL1 DOCK10 MLLT10 NID1 CD302 LIMCH1

1.38e-0419513177509_DN
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A

SETD1A DAG1 ITGA2B MED1 NFIX WDFY3 BRWD1

1.38e-0419513173755_DN
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A

KANSL1L HIPK2 SPART PMEL PDPN RBFOX1 NID1

1.38e-0419513175569_UP
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

KANSL1L KAT6A PRDM2 RPAP1 CD302 WDFY3 FBXW7

1.43e-0419613175015_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A

SETD1A MAP4 AGGF1 PRDM2 ITPR2 PTP4A3 VCAN

1.43e-0419613171864_DN
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A

KAT6A HIPK2 ZNF280B ITPR2 NFIX TP63 LPP

1.43e-0419613174291_UP
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A

MAP4 ZNF280B NUP214 PIK3C2G TP63 VCAN RBFOX1

1.43e-0419613172174_UP
DrugMidodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A

KANSL1L FRAS1 MAP4 MLXIP TP63 ZFHX2 NID1

1.43e-0419613172250_UP
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A

HIPK2 PRDM2 HSPA12A PTPRZ1 TP63 RBFOX1 NID1

1.43e-0419613175533_UP
DrugPentolinium bitartrate [52-62-0]; Down 200; 7.4uM; HL60; HT_HG-U133A

SETD1A STK17B HIPK2 CLEC7A RPAP1 ASCC2 NUMB

1.47e-0419713172343_DN
DrugYohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; HL60; HG-U133A

MAP4 GIN1 BAG3 NUP214 PMEL LUZP1 HR

1.47e-0419713171763_UP
DrugTodralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A

HIPK2 MECOM NUP214 LUZP1 ITPR3 HSPA12A PTP4A3

1.47e-0419713175512_UP
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

MAP4 NUP214 LUZP1 PRDM2 PTP4A3 RPAP1 KLF5

1.47e-0419713171674_DN
DrugDebrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A

SETD1A STK17B ARHGAP26 MECOM ITGA2B MLXIP PTP4A3

1.47e-0419713176688_UP
DrugCatechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

MAP4 KAT6A AGGF1 MLLT10 LUZP1 KLF5 TACC1

1.52e-0419813174837_DN
DrugSR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A

KANSL1L MAP4 ARHGAP26 DOCK10 HIPK2 MED1 NID1

1.52e-0419813174977_UP
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA

HIPK2 PRDM2 PTP4A3 LPP ZFHX2 LIMCH1 WDFY3

1.52e-0419813171002_UP
Drugrotenone; Up 200; 1uM; PC3; HT_HG-U133A

ARHGAP26 DOCK10 PTP4A3 CELSR2 TP63 RBFOX1 HR

1.52e-0419813175948_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; MCF7; HT_HG-U133A

FRAS1 MECOM TP63 SETBP1 RBFOX1 NUMB HR

1.52e-0419813173884_UP
DrugOxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A

MAP4 KAT6A HIPK2 MLLT10 ITPR2 PTP4A3 PARM1

1.52e-0419813175094_DN
DrugNialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A

ZNF280B NUP214 ITGA2B ITPR3 PTP4A3 VCAN ZFHX2

1.52e-0419813174525_UP
Drugnovobiocin sodium, USP; Down 200; 100uM; MCF7; HG-U133A

SETD1A MAP4 ARHGAP26 LUZP1 ITPR2 TP63 SVIL

1.52e-041981317342_DN
DrugTerbutaline hemisulfate [23031-32-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A

SETD1A HIPK2 NUP214 HSPA12A KLF5 ZFHX2 NID1

1.57e-0419913176240_UP
Drug15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

PRDM2 ITPR3 PTP4A3 VCAN TENM1 WDFY3 HR

1.57e-0419913177494_DN
DrugCarbamazepine [298-46-4]; Down 200; 17uM; MCF7; HT_HG-U133A

MAP4 MLLT10 ITPR3 HSPA12A UBAP2L NUMB TACC1

1.57e-0419913171683_DN
DrugNitrofural [59-87-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A

MAP4 STK17B SNUPN PRDM2 UBAP2L CLINT1 RPAP2

1.57e-0419913175321_DN
Drug(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A

MFSD6 SPART MLLT10 UBAP2L SETBP1 PARM1 FBXW7

1.57e-0419913174543_DN
Drugtrypanothione disulfide

DAG1 ITGA2B VCAN SETBP1 NID1 VCAM1

1.62e-041401316CID000115098
DrugNifedipine [21829-25-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

SETD1A MAP4 KAT6A PRDM2 PTP4A3 LPP ZFHX2

1.62e-0420013171692_UP
DrugBupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; PC3; HT_HG-U133A

KAT6A MLLT10 PTP4A3 LIMCH1 WDFY3 PARM1 FBXW7

1.62e-0420013175782_DN
DiseaseLeukemia, Myelocytic, Acute

ARHGAP26 MECOM NUP214 MLLT10 SETBP1 SVIL LPP

1.34e-051731327C0023467
Diseasegranulins measurement

CDH23 ITGA2B CELSR2

1.87e-05121323EFO_0008141
DiseaseAcute myeloid leukemia

NUP214 MLLT10 LPP

5.68e-05171323cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

NUP214 MLLT10 LPP

5.68e-05171323601626
Diseaseprogranulin measurement

CDH23 ITGA2B CELSR2

1.27e-04221323EFO_0004625
Diseaseresponse to opioid

MUC16 CACNA2D4 TP63 RBFOX1

1.64e-04611324EFO_0008541
DiseaseMyelomonocytic leukemia

ARHGAP26 SETBP1

1.97e-0451322C0027019
DiseaseAcute Myeloid Leukemia, M1

MECOM NUP214 MLLT10 SVIL LPP

2.53e-041251325C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

MECOM NUP214 MLLT10 SVIL LPP

2.53e-041251325C1879321
Diseasechronic obstructive pulmonary disease

SETD1A FRAS1 BAG3 DOCK10 MECOM RPAP1 SVIL RBFOX1 EPC1 ASCC2 DOT1L

2.76e-0468813211EFO_0000341
Diseaseintellectual disability (implicated_via_orthology)

KANSL1L ZNF280B ITGA2B RBFOX1

3.64e-04751324DOID:1059 (implicated_via_orthology)
DiseaseQRS duration

ARHGAP24 CEP85L BAG3 ANKRD50 CACNA2D4 SETBP1 RBFOX1

4.02e-042981327EFO_0005055
Diseaseplatelet reactivity measurement, thrombus formation measurement

SETBP1 SVIL

4.11e-0471322EFO_0004985, EFO_0007615
Diseasecytomegalovirus infection, response to allogeneic hematopoietic stem cell transplant

RBFOX1 NID1

5.46e-0481322EFO_0001062, EFO_0007044
Diseaseacute myeloid leukemia (is_implicated_in)

KAT6A NUP214 MLLT10 LPP

5.60e-04841324DOID:9119 (is_implicated_in)
Diseasenasopharyngeal neoplasm

MECOM MED1 RBFOX1 EPC1 TNFRSF19

6.03e-041511325EFO_0004252
DiseaseCancer of Nasopharynx

MECOM TNFRSF19

7.00e-0491322C0238301
DiseaseNasopharyngeal Neoplasms

MECOM TNFRSF19

7.00e-0491322C0027439
DiseaseAnemia, Sickle Cell

CAD VCAM1

8.73e-04101322C0002895
Diseaserenal cell carcinoma

CEP85L ITPR2 RBFOX1

8.84e-04421323EFO_0000681
Diseasevolumetric bone mineral density

MAP4K3 FHAD1 RBFOX1

8.84e-04421323EFO_0007620
DiseaseAdenoid Cystic Carcinoma

KAT6A VCAN ASPM FBXW7

1.08e-031001324C0010606
DiseaseColorectal Carcinoma

CAD RPAP1 CD226 KLF5 TP63 SETBP1 TENM1 NID1 FBXW7 HR

1.26e-0370213210C0009402
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR2 ITPR3

1.27e-03121322DOID:1441 (implicated_via_orthology)
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CDH23 CELSR2

1.27e-03121322EFO_0801493
Diseasemean corpuscular hemoglobin concentration

ATMIN DENND4A DAG1 MECOM PHGDH E2F8 ITPR2 SUSD1 CD226 UBAP2L RBFOX1 ASCC2 DOT1L

1.40e-03110513213EFO_0004528
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

NUP214 MLLT10 FBXW7

1.74e-03531323C1961099
DiseasePneumoconiosis

CDH23 PTPRZ1

1.74e-03141322C0032273
DiseaseBagassosis

CDH23 PTPRZ1

1.74e-03141322C0004681
Diseasehair morphology measurement

ZCCHC8 MLXIP TNFRSF19

1.84e-03541323EFO_0007821
Diseasewhite matter microstructure measurement

DAG1 MECOM MLLT10 VCAN SETBP1 WDFY3 SOS1

1.92e-033901327EFO_0005674
Diseaselymphocyte:monocyte ratio

DOCK10 LPP CD302 VCAM1 KNL1 RPAP2

1.93e-032881326EFO_0600088
Diseaseacute graft vs. host disease, donor genotype effect measurement

AGGF1 RBFOX1

2.01e-03151322EFO_0004599, EFO_0007892
DiseaseAutosomal recessive primary microcephaly

ASPM KNL1

2.01e-03151322cv:C3711387
DiseaseRASopathy

ARHGAP26 SOS1

2.01e-03151322cv:C5555857
Diseaseplatelet component distribution width

DOCK10 MECOM ITGA2B CD226 SVIL LPP EPC1 NUMB CLINT1 BRWD1

2.15e-0375513210EFO_0007984
DiseaseDermatitis

FLG VCAM1

2.29e-03161322C0011603
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

ASPM KNL1

2.29e-03161322DOID:0070296 (is_implicated_in)
Diseaseprostate carcinoma, type 2 diabetes mellitus

UBAP2 MBNL1 KNL1

2.37e-03591323EFO_0001663, MONDO_0005148
DiseaseAdenocarcinoma of lung (disorder)

KSR2 KLF5 TP63 DOT1L SOS1

2.39e-032061325C0152013
DiseasePROSTATE CANCER, HEREDITARY, 1

MBNL1 MECOM KNL1

2.49e-03601323C4722327
DiseaseMultiple congenital anomalies

TP63 SETBP1

2.58e-03171322C0000772
DiseaseDisorder of eye

FRAS1 CDH23 CACNA2D4 VCAN USH2A

2.70e-032121325C0015397
Diseaseelectrocardiography

ARHGAP24 CEP85L BAG3 LUZP1 HMCN2 SETBP1 SVIL MANSC4

2.71e-035301328EFO_0004327
DiseaseMyeloid Leukemia

MECOM SETBP1

2.90e-03181322C0023470
DiseaseLeukemia, Monocytic, Chronic

MECOM SETBP1

2.90e-03181322C0023466
Diseasecardiac troponin T measurement

TRABD2A BAG3 CDH23 MECOM RBFOX1

3.10e-032191325EFO_0005043
Diseasecerebral infarction (is_marker_for)

BRINP3 SOS1

3.23e-03191322DOID:3526 (is_marker_for)
DiseaseJuvenile Myelomonocytic Leukemia

ARHGAP26 SETBP1

3.23e-03191322C0349639
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

DOCK10 CDH23 GRIA4 HSPA12A CNTNAP5 UBAP2L SETBP1 RBFOX1 USH2A BRWD1

3.29e-0380113210EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseAbnormality of refraction

SMG1 KSR2 GRIA4 ITPR2 CNTNAP5 RGS18 NFIX RBFOX1 ASCC2

3.35e-036731329HP_0000539
DiseaseMYELODYSPLASTIC SYNDROME

ARHGAP26 MECOM SETBP1

3.40e-03671323C3463824
DiseaseVertigo

CDH23 PRDM2 SVIL LIMCH1

3.58e-031391324HP_0002321
Diseasecitrulline measurement

MECOM HMCN2

3.58e-03201322EFO_0009777
Diseasealpha-tocopherol measurement

USH2A SOS1

3.58e-03201322EFO_0007898
DiseaseProstate cancer, familial

MBNL1 MECOM KNL1

3.70e-03691323C2931456
Diseaseplatelet crit

MFSD6 DOCK10 DAG1 MECOM ITGA2B ITPR2 CD226 NFIX SVIL NUMB DOT1L

3.73e-0395213211EFO_0007985
Diseasebiological sex

BRINP3 ZCCHC8 CNTNAP5 RGS18 SETBP1

3.82e-032301325PATO_0000047
DiseaseAgents acting on the renin-angiotensin system use measurement

HIPK2 MECOM PTP4A3 CELSR2 SAP130 PCDH18

4.06e-033351326EFO_0009931
DiseaseAutosomal Recessive Primary Microcephaly

ASPM KNL1

4.33e-03221322C3711387
DiseasePrimary microcephaly

ASPM KNL1

4.33e-03221322C0431350
Diseasepentachlorophenol measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022071
Diseaseparathion measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022070
Diseasepotassium chromate measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022072
Diseasemercuric chloride measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022068
Diseaseheptachlor epoxide measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022067
Diseasemethoxychlor measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022069
Disease4,6-dinitro-o-cresol measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022053
Disease2,4,5-trichlorophenol measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022052
Diseaseazinphos methyl measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022055
Diseasealdrin measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022054
Diseasedicofol measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022060
Diseasedisulfoton measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022062
Diseasedieldrin measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022061
Diseaseendrin measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022064
Diseaseendosulfan measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022063
Diseaseheptachlor measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022066
Diseaseethion measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022065
Diseasechlorpyrifos measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022057
Diseasecadmium chloride measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022056
Diseasediazinon measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022059
Diseasedibutyl phthalate measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0022058
Diseaseenvironmental exposure measurement

MUC16 CNTNAP5 USH2A

4.33e-03731323EFO_0008360
Diseasebody weight

DMTF1 BRINP3 MBNL1 KSR2 MECOM SNUPN MLLT10 SPATA31C1 SUSD1 SETBP1 LPP RBFOX1 DOT1L

4.36e-03126113213EFO_0004338

Protein segments in the cluster

PeptideGeneStartEntry
CSNVPVSTINHAFSS

TACC1

536

O75410
STPSNNVHTSLSHVQ

ZNF280B

216

Q86YH2
FTQVHNLPESDSEST

C2orf16

1256

Q68DN1
HSPVNQFANTSETNT

EPC1

491

Q9H2F5
AVAAVSDQHATSPFD

BRINP3

31

Q76B58
QNFSDSSESDTHPFV

VCAN

1441

P13611
ADSLHTSFNIQVSPS

ADGRG4

1756

Q8IZF6
HSDSRFTTVFSTAPQ

CD302

196

Q8IX05
TVTAEAVSQASSHPE

ASCC2

431

Q9H1I8
STQAVTFSPSFHNQA

AKAP11

736

Q9UKA4
HFASNSQEPASALAT

AGGF1

166

Q8N302
SSTATAQTVPIDSFH

ANKRD50

1196

Q9ULJ7
AQTVPIDSFHNLSFT

ANKRD50

1201

Q9ULJ7
NVTDANTHRPVFQSS

CELSR2

701

Q9HCU4
SHVQSSPVQSDSSTA

FLG

3911

P20930
LHAQTVSQTAASSPQ

DOT1L

436

Q8TEK3
SENSPVSSFVAHVLA

CDH23

1861

Q9H251
QITHVSSADSPATVD

DMTF1

466

Q9Y222
HQAVFSQCPALQTSS

DISP2

1221

A7MBM2
SQIHFLSPDSFVNNS

ASPM

311

Q8IZT6
QDTLTHSSPSFNLDT

DENND4A

1296

Q7Z401
FVNQPHSSSQVSLGF

PIK3C2G

26

O75747
SDNSTSLQTHQPVFI

ITPR2

1496

Q14571
SSPFSENSTSLQTHQ

ITPR3

1481

Q14573
VTISSNHVPENFSLE

PCDH18

806

Q9HCL0
HSIFSPSLEEQTAVS

MECOM

641

Q03112
SESTAQQFSEPQHTQ

MUC16

521

Q8WXI7
NSVAVSASPTHENSV

MUC16

2006

Q8WXI7
PHQFITSTNTFTDVS

MUC16

4356

Q8WXI7
NTEAVHPSTNTAASN

MUC16

7171

Q8WXI7
STQEDTTVAISTPHF

MUC16

7216

Q8WXI7
HSATTQRFPQSVVTT

MUC16

9396

Q8WXI7
FTNISLVTHPAESSS

MUC16

11261

Q8WXI7
FTESDTPQTNVTHVT

MAP4K3

766

Q8IVH8
DAIVDFSSQHSTPSL

PARP15

426

Q460N3
HNPTDLFDSVTNNTR

PARP15

641

Q460N3
SHSNFTAVSNVNVLS

KANSL1L

736

A0AUZ9
ASALHFPSTSIIQQS

NFIX

366

Q14938
FETITDNTPFTSVNH

FRAS1

3241

Q86XX4
HVQVFSPHTLQSSAF

HIPK2

11

Q9H2X6
SVEALNSPHSESFVS

MAP4

191

P27816
VAVPAVTSADSQFSQ

LYSMD4

276

Q5XG99
DQNASTHTPQSSVKT

CLINT1

301

Q14677
APQVSIHTSSQHFSQ

HMCN2

606

Q8NDA2
FINSFGNASSIPTVH

KIAA2026

1966

Q5HYC2
PVHTEANFSANTLSV

KSR2

381

Q6VAB6
STPIQHSFLTDVSDV

CCDC28A

161

Q8IWP9
NGSHIPQTSSVFSIE

DAG1

141

Q14118
SSIPTDSSNHQVLEA

FETUB

156

Q9UGM5
VTQHFLSPETSALSA

HR

1136

O43593
PHVDNIETANSFAVT

GRIA4

66

P48058
ITTTENATHSTPNFT

MUC3A

2131

Q02505
SSQVPIVFENTDLHS

NID1

446

P14543
THSFGNPSISVSTQQ

LPP

26

Q93052
TEAPSSTTHQDLVVN

MANSC4

171

A6NHS7
LSSAVPSQSSIHSFD

NUP214

896

P35658
AYNLAPESTSESHSQ

KNL1

616

Q8NG31
TDSPNTAVSVHVSES

ACBD3

436

Q9H3P7
LSPSHIVNDTDSNVS

HSPA12A

36

O43301
SATSPHQSQQSTVDV

PRDM10

951

Q9NQV6
NNFSVQPTHTVSQAS

PTPRZ1

1121

P23471
SPTSSVTSENSEVFH

PTPRZ1

1596

P23471
PEVFSASVTTNHSST

PARM1

166

Q6UWI2
EETPTTTSHSQAFNF

MFSD6

421

Q6ZSS7
SFSVQEVQVDSSHLP

POLA1

316

P09884
NSSANSTETLQHVPS

TMEM123

46

Q8N131
QHVPSDHTNETSNST

TMEM123

56

Q8N131
VTTFSQSLHTAVPTA

POM121

896

Q96HA1
VIDFHNPSDSISITS

FKBP9

361

O95302
PSVSDHSQQVVDSGF

KAT6A

1536

Q92794
TLTHDAPATTFSQSQ

MLXIP

491

Q9HAP2
TSPYNTDHAQNSVTA

TP63

131

Q9H3D4
AVPFSLDSVANSIHS

ATP6AP2

101

O75787
PSFDSNTDVHTVASL

ARHGAP24

196

Q8N264
SFDSQVSLPISVHTQ

ATMIN

446

O43313
FSSVETQTSAEPHTV

ATMIN

806

O43313
SVQIEPVHTEAFSSS

FHAD1

1111

B1AJZ9
PVHTEAFSSSQEQQS

FHAD1

1116

B1AJZ9
LSPTHINATASETFT

CCDC150

16

Q8NCX0
STFVVSTVNTQDPHV

DOCK10

846

Q96BY6
TSSELTAVNFPSFHV

E2F8

681

A0AVK6
TNISESHPNATFSAV

IGHM

271

P01871
SNAHFSNLPVNTSIS

CACNA2D4

191

Q7Z3S7
HTFDSSSSQHPISTQ

GAB4

461

Q2WGN9
NSVTNSSSIVDLPVH

FBXW7

141

Q969H0
SLQTPFSEESVSHSQ

CEP85L

426

Q5SZL2
ENQLLPVSSSHTAQS

BRWD1

1696

Q9NSI6
PVSSSHTAQSNVDES

BRWD1

1701

Q9NSI6
LTSVSNHVSSPFELS

LUZP1

831

Q86V48
SATSVPFAATATANQ

MBNL1

356

Q9NR56
FANTHTAPATVVLVS

MARF1

436

Q9Y4F3
ESSQPNTSSHNISVI

GEN1

566

Q17RS7
QSDSFEAAVPSNSHI

CD226

126

Q15762
RFPSVTSNEHFSTAE

ERICH5

16

Q6P6B1
HTETQQPEATAAATS

BAG3

546

O95817
SSPVVVQHSVASQAS

CEP295

1101

Q9C0D2
DVNAVTTVHSSSDPF

CNTNAP5

1206

Q8WYK1
SESRFSVSFQHPVND

MED1

446

Q15648
NIELASSEPQHFTTT

LIMCH1

651

Q9UPQ0
TATNFTTHNIPQTFT

PRDM2

1316

Q13029
SPTFQANGTDSAFHV

NUMB

361

P49757
TPFIFEHTVNNSTAV

FNDC8

181

Q8TC99
AFSQISEHSVFTPTE

ARHGAP20

956

Q9P2F6
TESSHALNISTPQEA

USH2A

2041

O75445
THSEQSPADTSAQTV

RBFOX1

71

Q9NWB1
STLTLSPVSFENEHS

VCAM1

366

P19320
QAHDLSPAAESSSTF

SVIL

216

O95425
SESTVHAQEQSPSAT

PDPN

86

Q86YL7
HAQEQSPSATASNVA

PDPN

91

Q86YL7
SAVSFAFNVTHLEPT

GIN1

266

Q9NXP7
NNVTSPEFTSVQHGS

SMG1

111

Q96Q15
SFTAGTVFDNVHPSQ

ARHGAP26

776

Q9UNA1
LFHPEETSSSSQTQD

STK17B

301

O94768
VQAHPYSTTFQESAS

TEKT4

226

Q8WW24
STQDVQSSPHNQFTF

TENM1

176

Q9UKZ4
TSSAPFTINAHQSDI

WDR45

181

Q9Y484
QHSSLETTSRQPAFQ

SPATA3

56

Q8NHX4
SFSVSQDLNSTAAPH

SNUPN

11

O95149
HVSSQSLSFDSSNPE

ITGA2B

246

P08514
ASVVPHASENLASQV

SPATA31C1

891

P0DKV0
AHSSSAFTITDQVPF

PMEL

201

P40967
SPFHSSNDTVFIQVT

SOS1

1111

Q07889
HQQTEVSFSEPASDA

REELD1

471

A0A1B0GV85
TNESVPFAQHSSLDS

SETD1A

476

O15047
NQENVSHLSVSSASP

MLLT10

486

P55197
HTFSAQTAPTTDSLN

MLLT10

796

P55197
NHSQPTQSSLEDSVT

CLEC7A

91

Q9BXN2
SFSSAPQHAEVNGNT

SPART

131

Q8N0X7
PHSQASEANSFETSQ

UBAP2

301

Q5T6F2
EVPHGSQSSESFQFQ

ZCCHC8

451

Q6NZY4
ITHNPTNATLSTFIE

PTP4A3

21

O75365
GHETSIIPNSTAFQD

WDFY3

1486

Q8IZQ1
QTAISQPASGNTFSH

UBAP2L

321

Q14157
FSSSDQILSHDTSAP

ZFHX2

181

Q9C0A1
ITNSITQPTLHSFDA

RGS18

161

Q9NS28
HDSTFPLIDSSSQNQ

RPAP2

486

Q8IXW5
SHATSFNFTTREQVP

SUSD1

441

Q6UWL2
EVTTSHLANPNFTSN

THAP5

226

Q7Z6K1
APAATTVVQTHSQSA

SAP130

641

Q9H0E3
TVVQTHSQSASTNAP

SAP130

646

Q9H0E3
QPASSFQVETASQGH

XRN1

1661

Q8IZH2
LSHDSSQVPNFINAT

TRABD2A

266

Q86V40
HVNSFIFSQDPQSSD

RPAP1

1311

Q9BWH6
TSQNHGFAVETDSLP

CAD

291

P27708
ATSTSDPAQHLQLTQ

ZBTB24

661

O43167
HRDSIQSSDFSPTVN

WDR38

146

Q5JTN6
PVQSHSENFTAATDL

TNFRSF19

361

Q9NS68
VNAQALTSAFSPHTK

PHGDH

316

O43175
FSAETHSAASFPQQV

VSIG10L

181

Q86VR7
NVSSASNPENDSSHV

SETBP1

386

Q9Y6X0
QSLFHITASQPADSA

TRAV6

111

A0A075B6T7
NQFISSEPTALHSSE

ZBTB26

201

Q9HCK0
SFHSSPALENATITI

HSD52

36

Q0P140
SIFSSHQTAAPEVNN

KLF5

191

Q13887