Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	MYH2 CCT8L2 DHX37 ATP8A2 MYO1H RNF213 YTHDC2 CHD6 BTAF1 CHD7 TOP6BL CCT8L1P DDX21 DNAH7 MYO5C	3.65e-08	614	84	15	GO:0140657
GeneOntologyMolecularFunction	helicase activity	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	5.45e-05	158	84	6	GO:0004386
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX37 ATP8A2 RNF213 YTHDC2 CHD6 BTAF1 CHD7 DDX21 DNAH7	9.80e-05	441	84	9	GO:0016887
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	1.73e-04	5	84	2	GO:0140444
GeneOntologyMolecularFunction	actin binding	MYH2 MYLK SYNE1 MYO1H SYNE2 SNTG2 FHOD3 EPB41 MYO5C	1.83e-04	479	84	9	GO:0003779
GeneOntologyMolecularFunction	snoRNA binding	DHX37 PRKDC DDX21	3.91e-04	34	84	3	GO:0030515
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ARL6 DHX37 ATP8A2 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7	3.94e-04	775	84	11	GO:0017111
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD6 BTAF1 CHD7	5.03e-04	37	84	3	GO:0140658
GeneOntologyMolecularFunction	microfilament motor activity	MYH2 MYO1H MYO5C	5.45e-04	38	84	3	GO:0000146
GeneOntologyMolecularFunction	7SK snRNA binding	DDX21 LARP7	6.18e-04	9	84	2	GO:0097322
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYH2 GOLGA8J MYLK EPB41L4B SYNE1 MYO1H PAFAH1B1 SYNE2 GOLGA8H SNTG2 FHOD3 EPB41 MYO5C	6.49e-04	1099	84	13	GO:0008092
GeneOntologyMolecularFunction	pyrophosphatase activity	ARL6 DHX37 ATP8A2 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7	7.62e-04	839	84	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ARL6 DHX37 ATP8A2 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7	7.70e-04	840	84	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ARL6 DHX37 ATP8A2 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7	7.70e-04	840	84	11	GO:0016818
GeneOntologyMolecularFunction	protein-membrane adaptor activity	ATG16L1 SYNE1 SYNE2	8.97e-04	45	84	3	GO:0043495
GeneOntologyMolecularFunction	U3 snoRNA binding	DHX37 PRKDC	9.38e-04	11	84	2	GO:0034511
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH2 MYO1H DNAH7 MYO5C	1.55e-03	118	84	4	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD6 BTAF1 CHD7 TOP6BL	2.03e-03	127	84	4	GO:0008094
GeneOntologyMolecularFunction	actin filament binding	MYH2 SYNE1 MYO1H FHOD3 MYO5C	2.71e-03	227	84	5	GO:0051015
GeneOntologyMolecularFunction	calmodulin binding	MYH2 MYLK MKNK2 EPB41 MYO5C	2.86e-03	230	84	5	GO:0005516
GeneOntologyBiologicalProcess	negative regulation of chromatin binding	SENP2 BTAF1 LARP7	7.94e-06	10	85	3	GO:0035562
GeneOntologyCellularComponent	Golgi cisterna membrane	SORT1 GOLGA8IP GOLGA8J GOLGA8H ARAP1	4.08e-05	94	85	5	GO:0032580
GeneOntologyCellularComponent	Golgi cisterna	SORT1 GOLGA8IP GOLGA8J GOLGA8H ARAP1	2.26e-04	135	85	5	GO:0031985
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8IP GOLGA8J GOLGA8H	3.24e-04	33	85	3	GO:0000137
GeneOntologyCellularComponent	Golgi stack	SORT1 GOLGA8IP GOLGA8J GOLGA8H ARAP1	6.68e-04	171	85	5	GO:0005795
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	8.78e-04	11	85	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	8.78e-04	11	85	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	8.78e-04	11	85	2	GO:0106083
GeneOntologyCellularComponent	chaperonin-containing T-complex	CCT8L2 CCT8L1P	8.78e-04	11	85	2	GO:0005832
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	8.78e-04	11	85	2	GO:0106094
Domain	ARM-type_fold	DOCK1 FOCAD USP34 SARM1 VEPH1 FHOD3 BTAF1 PRKDC TAF2 TANGO6	2.04e-06	339	81	10	IPR016024
Domain	Helicase_C	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.03e-06	107	81	6	PF00271
Domain	HELICc	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.03e-06	107	81	6	SM00490
Domain	Helicase_C	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.42e-06	108	81	6	IPR001650
Domain	HELICASE_CTER	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.82e-06	109	81	6	PS51194
Domain	HELICASE_ATP_BIND_1	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.82e-06	109	81	6	PS51192
Domain	DEXDc	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	7.82e-06	109	81	6	SM00487
Domain	Helicase_ATP-bd	DHX37 YTHDC2 CHD6 BTAF1 CHD7 DDX21	8.25e-06	110	81	6	IPR014001
Domain	DEAH_ATP_HELICASE	DHX37 YTHDC2 CHD6 CHD7	2.17e-05	38	81	4	PS00690
Domain	KASH	SYNE1 SYNE2	1.11e-04	4	81	2	PF10541
Domain	KASH	SYNE1 SYNE2	1.11e-04	4	81	2	IPR012315
Domain	KASH	SYNE1 SYNE2	1.11e-04	4	81	2	PS51049
Domain	KASH	SYNE1 SYNE2	1.11e-04	4	81	2	SM01249
Domain	BRK	CHD6 CHD7	2.76e-04	6	81	2	SM00592
Domain	BRK_domain	CHD6 CHD7	2.76e-04	6	81	2	IPR006576
Domain	BRK	CHD6 CHD7	2.76e-04	6	81	2	PF07533
Domain	P-loop_NTPase	ARL6 MYH2 DHX37 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7 MYO5C	2.80e-04	848	81	12	IPR027417
Domain	SNF2_N	CHD6 BTAF1 CHD7	3.56e-04	32	81	3	IPR000330
Domain	SNF2_N	CHD6 BTAF1 CHD7	3.56e-04	32	81	3	PF00176
Domain	DNA/RNA_helicase_DEAH_CS	DHX37 CHD6 CHD7	4.65e-04	35	81	3	IPR002464
Domain	PH_dom-like	ARHGAP15 EPB41L4B VEPH1 DEF6 SNTG2 PLEKHB1 EPB41 ARAP1	5.15e-04	426	81	8	IPR011993
Domain	-	SORT1 NBAS ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	6.04e-04	333	81	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SORT1 NBAS ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	6.26e-04	335	81	7	IPR015943
Domain	-	PIKFYVE CCT8L2	9.96e-04	11	81	2	3.30.260.10
Domain	TCP-1-like_intermed	PIKFYVE CCT8L2	9.96e-04	11	81	2	IPR027410
Domain	PH	ARHGAP15 VEPH1 DEF6 SNTG2 PLEKHB1 ARAP1	1.31e-03	278	81	6	SM00233
Domain	WD_REPEATS_1	NBAS ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	1.31e-03	278	81	6	PS00678
Domain	WD_REPEATS_2	NBAS ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	1.34e-03	279	81	6	PS50082
Domain	WD_REPEATS_REGION	NBAS ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	1.34e-03	279	81	6	PS50294
Domain	PH_DOMAIN	ARHGAP15 VEPH1 DEF6 SNTG2 PLEKHB1 ARAP1	1.34e-03	279	81	6	PS50003
Domain	PH_domain	ARHGAP15 VEPH1 DEF6 SNTG2 PLEKHB1 ARAP1	1.36e-03	280	81	6	IPR001849
Domain	FERM-adjacent	EPB41L4B EPB41	1.40e-03	13	81	2	IPR014847
Domain	Peptidase_M1	ANPEP TAF2	1.40e-03	13	81	2	PF01433
Domain	FA	EPB41L4B EPB41	1.40e-03	13	81	2	SM01195
Domain	FA	EPB41L4B EPB41	1.40e-03	13	81	2	PF08736
Domain	Peptidase_M1_N	ANPEP TAF2	1.40e-03	13	81	2	IPR014782
Domain	-	ARL6 DHX37 RNF213 YTHDC2 GNA15 CHD6 BTAF1 CHD7 DDX21 DNAH7	1.41e-03	746	81	10	3.40.50.300
Domain	-	ARHGAP15 EPB41L4B VEPH1 DEF6 PLEKHB1 EPB41 ARAP1	1.54e-03	391	81	7	2.30.29.30
Domain	Cpn60/TCP-1	PIKFYVE CCT8L2	1.88e-03	15	81	2	IPR002423
Domain	Cpn60_TCP1	PIKFYVE CCT8L2	1.88e-03	15	81	2	PF00118
Domain	-	PIKFYVE CCT8L2	1.88e-03	15	81	2	3.50.7.10
Domain	Myosin_N	MYH2 MYO5C	1.88e-03	15	81	2	PF02736
Domain	Myosin_N	MYH2 MYO5C	1.88e-03	15	81	2	IPR004009
Domain	GroEL-like_apical_dom	PIKFYVE CCT8L2	1.88e-03	15	81	2	IPR027409
Domain	DUF1605	DHX37 YTHDC2	2.42e-03	17	81	2	IPR011709
Domain	OB_NTP_bind	DHX37 YTHDC2	2.42e-03	17	81	2	PF07717
Domain	GOLGA2L5	GOLGA8J GOLGA8H	2.72e-03	18	81	2	PF15070
Domain	Golgin_A	GOLGA8J GOLGA8H	2.72e-03	18	81	2	IPR024858
Domain	HA2	DHX37 YTHDC2	2.72e-03	18	81	2	SM00847
Domain	HA2	DHX37 YTHDC2	2.72e-03	18	81	2	PF04408
Domain	Helicase-assoc_dom	DHX37 YTHDC2	2.72e-03	18	81	2	IPR007502
Domain	CH	EHBP1L1 SYNE1 SYNE2	2.83e-03	65	81	3	SM00033
Domain	Myosin-like_IQ_dom	MYH2 MYO5C	3.03e-03	19	81	2	IPR027401
Domain	-	MYH2 MYO5C	3.03e-03	19	81	2	4.10.270.10
Domain	PH	ARHGAP15 VEPH1 DEF6 PLEKHB1 ARAP1	3.19e-03	229	81	5	PF00169
Domain	CH	EHBP1L1 SYNE1 SYNE2	3.49e-03	70	81	3	PF00307
Domain	HEAT_REPEAT	BTAF1 PRKDC TANGO6	3.49e-03	70	81	3	PS50077
Domain	-	EHBP1L1 SYNE1 SYNE2	3.63e-03	71	81	3	1.10.418.10
Domain	Ez/rad/moesin-like	EPB41L4B EPB41	3.70e-03	21	81	2	IPR000798
Domain	DEAD/DEAH_box_helicase_dom	DHX37 YTHDC2 DDX21	3.93e-03	73	81	3	IPR011545
Domain	CH	EHBP1L1 SYNE1 SYNE2	3.93e-03	73	81	3	PS50021
Domain	DEAD	DHX37 YTHDC2 DDX21	3.93e-03	73	81	3	PF00270
Domain	Quino_amine_DH_bsu	NBAS WDR6	4.06e-03	22	81	2	IPR011044
Domain	CH-domain	EHBP1L1 SYNE1 SYNE2	4.24e-03	75	81	3	IPR001715
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 SYNE1 GNPTAB SYNE2 SENP2 CHD6 CHD7 ARAP1	8.50e-08	225	85	8	12168954
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 WDR6 DHX37 SYNE2 YTHDC2 SCAF11 CHD7 PRKDC DDX21 LARP7	4.49e-06	653	85	10	22586326
Pubmed	The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.	PIKFYVE MYH2 MYLK DEF6	5.01e-06	46	85	4	23793062
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	SYNE1 PAFAH1B1 SYNE2	5.03e-06	14	85	3	19874786
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PIKFYVE RGL1 TBRG4 SYNE2 DNAH7	5.35e-06	102	85	5	10231032
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	5.90e-06	2	85	2	22768332
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	5.90e-06	2	85	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	5.90e-06	2	85	2	24931616
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	5.90e-06	2	85	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	5.90e-06	2	85	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	5.90e-06	2	85	2	24586179
Pubmed	SLERT Regulates DDX21 Rings Associated with Pol I Transcription.	TBRG4 DDX21	5.90e-06	2	85	2	28475895
Pubmed	Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.	SORT1 LPA	5.90e-06	2	85	2	29973585
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	5.90e-06	2	85	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	5.90e-06	2	85	2	31578382
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DHX37 SYNE1 SYNE2 CHD7 TAF2 LARP7	9.23e-06	197	85	6	20811636
Pubmed	Analysis of the DNA sequence and duplication history of human chromosome 15.	GOLGA8IP GOLGA8J ANPEP GOLGA8H	1.11e-05	56	85	4	16572171
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK1 YTHDC2 BTAF1 CHD7 PRKDC CPSF2 DDX21 INTS8 ARAP1	1.29e-05	582	85	9	20467437
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	SORT1 LPA RNF213	1.33e-05	19	85	3	23118302
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 DPP6 EPB41L4B SOBP SLC22A23 RNF213 SNTG2 ANKMY1 SCAF11 CHD6 BTAF1 INTS8 EPB41 ARAP1	1.44e-05	1489	85	14	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PIKFYVE NBAS TBRG4 WDR6 SYNE1 SYNE2 SARM1 MRPL30 RNF213 SENP2 YTHDC2 MALSU1 DDX21 RBM20	1.52e-05	1496	85	14	32877691
Pubmed	RNA-binding proteins RBM20 and PTBP1 regulate the alternative splicing of FHOD3.	FHOD3 RBM20	1.77e-05	3	85	2	30468920
Pubmed	FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.	PRKDC FGFR2	1.77e-05	3	85	2	23300950
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	1.77e-05	3	85	2	10878022
Pubmed	LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration.	PAFAH1B1 SYNE2	1.77e-05	3	85	2	29934494
Pubmed	Wallerian degeneration: an emerging axon death pathway linking injury and disease.	SARM1 PLEKHB1	1.77e-05	3	85	2	24840802
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	1.77e-05	3	85	2	16079285
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	1.77e-05	3	85	2	12408964
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	1.77e-05	3	85	2	17462627
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD6 CHD7	1.77e-05	3	85	2	28533432
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	1.77e-05	3	85	2	33472039
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	1.77e-05	3	85	2	25516977
Pubmed	Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.	GOLGA8J GOLGA8H RLN1	2.41e-05	23	85	3	21111240
Pubmed	Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.	SORT1 GOLGA8J GOLGA8H	3.12e-05	25	85	3	15078902
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	3.53e-05	4	85	2	16648470
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	3.53e-05	4	85	2	23071752
Pubmed	RNA helicase DDX21 coordinates transcription and ribosomal RNA processing.	DDX21 LARP7	3.53e-05	4	85	2	25470060
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	3.53e-05	4	85	2	20108321
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	MYLK RNF213	3.53e-05	4	85	2	26147384
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	3.53e-05	4	85	2	19596800
Pubmed	Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.	MYH2 MYLK	3.53e-05	4	85	2	11029314
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	3.53e-05	4	85	2	28716842
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SORT1 USP34 NBAS MYH2 TBRG4 WDR6 SYNE2 MRPL30 RNF213 YTHDC2 BTAF1 PRKDC LARP7	4.58e-05	1440	85	13	30833792
Pubmed	Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.	GOLGA8J GOLGA8H LARP7	4.92e-05	29	85	3	20568244
Pubmed	Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.	GOLGA8J MYLK GOLGA8H	4.92e-05	29	85	3	30228103
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	RUFY2 SORT1 FOCAD TBC1D8 USP34 GPR37 SARM1 RNF213 BTAF1 PRKDC INTS8	5.49e-05	1061	85	11	33845483
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	5.87e-05	5	85	2	18396275
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	5.87e-05	5	85	2	22632968
Pubmed	The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.	GOLGA8J GOLGA8H EPB41	6.64e-05	32	85	3	23704327
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SORT1 TBC1D8 EHBP1L1 TBRG4 EPB41L4B WDR6 SYNE1 BTAF1 INTS8	6.67e-05	719	85	9	35337019
Pubmed	Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.	GOLGA8J PAFAH1B1 GOLGA8H	7.98e-05	34	85	3	23533177
Pubmed	Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.	DOCK1 FGFR2	8.80e-05	6	85	2	19307307
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	8.80e-05	6	85	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	8.80e-05	6	85	2	18827015
Pubmed	TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.	RUFY2 MYH2 ANPEP PRKDC DDX21 MYO5C	1.06e-04	305	85	6	33194618
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	EPB41L4B DHX37 SYNE1 MRPL30 MAP3K20 PRKDC TAF2 DDX21 EPB41 MYO5C	1.07e-04	949	85	10	36574265
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 VEPH1 FHOD3 TANGO6	1.18e-04	102	85	4	11214970
Pubmed	Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock.	CORIN FGFR2	1.23e-04	7	85	2	33037205
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DOCK1 NBAS BTAF1 PRKDC MYO5C	1.42e-04	202	85	5	33005030
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MYH2 EHBP1L1 TBRG4 SYNE2 CHD6 CHD7 TAF2 DNAH7	1.71e-04	638	85	8	31182584
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	WDR6 DHX37 PRKDC	1.74e-04	44	85	3	26471122
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	EPB41L4B WDR6 DHX37 YTHDC2 ELP2 BTAF1 HSD17B11 RBM20	1.94e-04	650	85	8	38777146
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RUFY2 PIKFYVE RGL1 GNPTAB SARM1 RNF213 TANGO6	2.10e-04	493	85	7	15368895
Pubmed	Nuclear membrane proteins with potential disease links found by subtractive proteomics.	SYNE1 SYNE2	2.62e-04	10	85	2	12958361
Pubmed	Genes to diseases (G2D) computational method to identify asthma candidate genes.	DOCK1 LPA	2.62e-04	10	85	2	18682798
Pubmed	Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.	SYNE1 SYNE2	2.62e-04	10	85	2	28533284
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	ARL6 ATP8A2 GNPTAB SYNE2 ARAP1	2.74e-04	233	85	5	32290105
Pubmed	Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes.	PIKFYVE CCT8L2 CCT8L1P	2.86e-04	52	85	3	20193073
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EHBP1L1 DHX37 SYNE1 CHD6 CHD7 PRKDC CPSF2 PPIH DDX21 INTS8	3.09e-04	1082	85	10	38697112
Pubmed	Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.	ATG16L1 PRKDC	3.20e-04	11	85	2	28973896
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	SYNE1 SYNE2	3.20e-04	11	85	2	22826121
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FOCAD PIKFYVE USP34 EHBP1L1 DEF6 SENP2 BTAF1 PRKDC FGFR2 ARAP1	3.64e-04	1105	85	10	35748872
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF11 PRKDC TAF2 CPSF2 PPIH	3.86e-04	251	85	5	31076518
Pubmed	A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.	PIKFYVE DHX37 CPSF2 DDX21 LARP7	4.07e-04	254	85	5	28431233
Pubmed	The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.	GOLGA8J GOLGA8H EPB41	4.15e-04	59	85	3	26371508
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE USP34 NBAS WDR6 RNF213 CHD6 CHD7 CPSF2	4.33e-04	733	85	8	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FOCAD ATG16L1 GOLGA8J EPB41L4B GPR37 RNF213 CHD6 PRKDC	4.45e-04	736	85	8	29676528
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	SYNE1 SYNE2	4.52e-04	13	85	2	21177258
Pubmed	Globozoospermia and lack of acrosome formation in GM130-deficient mice.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	28055014
Pubmed	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	33740186
Pubmed	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	32873390
Pubmed	GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	21552007
Pubmed	GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	29128360
Pubmed	Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.	GOLGA8J GOLGA8H	4.52e-04	13	85	2	28028212
Pubmed	High-throughput mapping of a dynamic signaling network in mammalian cells.	ATG16L1 ARHGAP15 MKNK2 VEPH1 PLEKHB1	4.53e-04	260	85	5	15761153
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	DPP6 GPR37 ATP8A2 SLITRK4 PLEKHB1 EPB41	4.84e-04	405	85	6	38187761
Pubmed	GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.	GOLGA8J GOLGA8H	5.27e-04	14	85	2	30630895
Pubmed	Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.	GOLGA8J GOLGA8H	5.27e-04	14	85	2	37831422
Pubmed	Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.	GOLGA8J GOLGA8H	5.27e-04	14	85	2	27226319
Pubmed	Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135.	MYH2 GNA15	5.27e-04	14	85	2	11409899
Pubmed	Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.	GOLGA8J GOLGA8H	5.27e-04	14	85	2	33543287
Pubmed	Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation.	GOLGA8J SYNE2 GOLGA8H	5.27e-04	64	85	3	34174788
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	RUFY2 DOCK1 TECTB BTAF1 FGFR2 DDX21	5.50e-04	415	85	6	16385451
Pubmed	Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.	RNF213 PPIH LARP7	5.52e-04	65	85	3	28276505
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SENP2 CHD6 CHD7 CPSF2	5.53e-04	153	85	4	10718198
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 WDR6 CHD6 CHD7 RBM20 TANGO6	5.72e-04	418	85	6	34709266
Pubmed	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.	GOLGA8J GOLGA8H	6.07e-04	15	85	2	26165940
Pubmed	Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.	GOLGA8J GOLGA8H	6.07e-04	15	85	2	17204322
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	GOLGA8J GOLGA8H	6.07e-04	15	85	2	16413118
Pubmed	Golgi disruption and early embryonic lethality in mice lacking USO1.	GOLGA8J GOLGA8H	6.07e-04	15	85	2	23185636
Cytoband	15q13.2	GOLGA8J GOLGA8H	6.95e-04	21	85	2	15q13.2
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	5.04e-05	4	53	2	1252
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP15 VEPH1 DEF6 PLEKHB1 ARAP1	3.37e-04	206	53	5	682
GeneFamily	WD repeat domain containing	ATG16L1 CFAP52 WDR6 PAFAH1B1 ELP2	1.00e-03	262	53	5	362
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	RUFY2 PIKFYVE	3.71e-03	31	53	2	81
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 GNPTAB SYNE2 RNF213 BTAF1 EPB41	1.10e-07	199	85	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE2 RNF213 SCAF11 BTAF1 DDX21 EPB41	1.14e-07	200	85	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP SLC22A23 FGFR2 SPRTN PLEKHB1 MYO5C	1.23e-06	179	85	6	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP SLC22A23 FGFR2 SPRTN PLEKHB1 MYO5C	1.23e-06	179	85	6	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 CHD7 FGFR2 PLEKHB1	1.58e-06	187	85	6	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 SYNE2 VEPH1 FGFR2 MYO5C	1.58e-06	187	85	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 CHD7 FGFR2 PLEKHB1	1.63e-06	188	85	6	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 CHD7 FGFR2 PLEKHB1	1.69e-06	189	85	6	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	1.96e-06	194	85	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP52 SYNE1 SLC22A23 SYNE2 TMC5 DNAH7	2.02e-06	195	85	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP52 SYNE1 SLC22A23 SYNE2 TMC5 DNAH7	2.02e-06	195	85	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	2.02e-06	195	85	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 MYLK TP53TG5 GPR37 FGFR2 PLEKHB1	2.08e-06	196	85	6	37a5f9f3988778655580bd0383811bb4930c1551
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 SYNE2 RNF213 BTAF1 EPB41	2.14e-06	197	85	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK1 SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	2.27e-06	199	85	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DPP6 SLC22A23 SYNE2 VEPH1 CHD7 MYO5C	2.27e-06	199	85	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	DPP6 SLC22A23 SYNE2 VEPH1 CHD7 MYO5C	2.34e-06	200	85	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DPP6 SLC22A23 SYNE2 VEPH1 CHD7 MYO5C	2.34e-06	200	85	6	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	COVID-19-kidney-Epithelial_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGAP15 DEF6 GNA15 C1GALT1C1L RLN1	3.43e-06	120	85	5	e17c85d41c781a29dec7e03a8b0637dccb4346bc
ToppCell	Control\|World / group, cell type (main and fine annotations)	SYNE1 SLC22A23 VEPH1 TMC5 MYO5C	1.76e-05	168	85	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP6 SYNE2 FHOD3 FGFR2 DNAH7	1.76e-05	168	85	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK MAP3K20 SNTG2 TOP6BL RBM20	1.87e-05	170	85	5	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK MAP3K20 SNTG2 TOP6BL RBM20	1.87e-05	170	85	5	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 SYNE2 RNF213 YTHDC2 BTAF1	1.92e-05	171	85	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK GPR37 ATP8A2 CORIN FHOD3	2.20e-05	176	85	5	4ed73c73972334f6dc4229920205547823252fa0
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	2.26e-05	177	85	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	2.26e-05	177	85	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CORIN SNTG2 FHOD3 CCT8L1P	2.26e-05	177	85	5	c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK CORIN SNTG2 FHOD3 CCT8L1P	2.26e-05	177	85	5	7ebdcedfe02da6d05bba3d625d8bd4c4ea96e4ad
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	2.26e-05	177	85	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	2.26e-05	177	85	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	2.26e-05	177	85	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D8 TYW3 DHX37 ATP8A2 PRKDC	2.33e-05	178	85	5	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP6 MYLK SYNE2 FHOD3 DNAH7	2.33e-05	178	85	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 EPB41L4B SLC22A23 VEPH1 MYO5C	2.39e-05	179	85	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	droplet-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP SLC22A23 FGFR2 PLEKHB1 MYO5C	2.59e-05	182	85	5	cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCell	droplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP SLC22A23 FGFR2 PLEKHB1 MYO5C	2.59e-05	182	85	5	d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell	droplet-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP SLC22A23 FGFR2 PLEKHB1 MYO5C	2.59e-05	182	85	5	7e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 VEPH1 FGFR2 MYO5C	2.66e-05	183	85	5	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.66e-05	183	85	5	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.73e-05	184	85	5	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 SYNE2 VEPH1 MYO5C	2.73e-05	184	85	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ATP8A2 VEPH1 FGFR2 TMC5 MYO5C	2.73e-05	184	85	5	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 VEPH1 FGFR2 MYO5C	2.73e-05	184	85	5	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	2.73e-05	184	85	5	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ATP8A2 VEPH1 FGFR2 TMC5 MYO5C	2.73e-05	184	85	5	2a8338e94937686a148b5433515700ca0f674058
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 VEPH1 FGFR2 MYO5C	2.80e-05	185	85	5	3bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	RUFY2 NBAS GNPTAB RNF213 PRKDC	2.80e-05	185	85	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CFAP52 SYNE1 GNPTAB SYNE2 RNF213	2.80e-05	185	85	5	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.80e-05	185	85	5	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.80e-05	185	85	5	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 VEPH1 FGFR2 MYO5C	2.87e-05	186	85	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.87e-05	186	85	5	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	RUFY2 NBAS GNPTAB RNF213 PRKDC	2.87e-05	186	85	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	USP34 MYLK GNPTAB SCAF11 SPRTN	2.87e-05	186	85	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.87e-05	186	85	5	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	2.95e-05	187	85	5	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFAP52 SYNE1 GNPTAB SYNE2 RNF213	2.95e-05	187	85	5	0bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	2.95e-05	187	85	5	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	3.02e-05	188	85	5	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	3.02e-05	188	85	5	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 SLC22A23 VEPH1 FGFR2 MYO5C	3.02e-05	188	85	5	43a0508d2524a5b310e89e9422843dcaab999bc3
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	3.02e-05	188	85	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 CHD7 PLEKHB1	3.02e-05	188	85	5	d9692b6048d9b85524a07a1807bdd4757731c151
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	3.02e-05	188	85	5	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	3.10e-05	189	85	5	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	3.10e-05	189	85	5	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	3.18e-05	190	85	5	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP52 FGFR2 TMC5 PLEKHB1 MYO5C	3.18e-05	190	85	5	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 FGFR2 PLEKHB1	3.18e-05	190	85	5	396b7225c2430db3dc55a3d0db70239b71987229
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	3.18e-05	190	85	5	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 TP53TG5 GPR37 CHD7 PLEKHB1	3.26e-05	191	85	5	2110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 GPR37 CHD7 FGFR2 PLEKHB1	3.26e-05	191	85	5	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	droplet-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP52 ANPEP FGFR2 PLEKHB1 MYO5C	3.26e-05	191	85	5	1b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SLC22A23 VEPH1 FGFR2 TMC5 MYO5C	3.34e-05	192	85	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYLK TP53TG5 GPR37 FGFR2 PLEKHB1	3.34e-05	192	85	5	8dc3016601148243196e925641c9507e9d58c9e0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 MYLK GPR37 FGFR2 PLEKHB1	3.42e-05	193	85	5	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 DOCK1 GOLGA8J GPR37 FGFR2	3.51e-05	194	85	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	SYNE1 SLC22A23 SYNE2 FGFR2 TMC5	3.60e-05	195	85	5	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	SYNE1 SLC22A23 SYNE2 FGFR2 TMC5	3.60e-05	195	85	5	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SORT1 VEPH1 FHOD3 TOP6BL FGFR2	3.69e-05	196	85	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP52 SYNE1 SYNE2 TMC5 DNAH7	3.69e-05	196	85	5	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP52 SYNE1 SYNE2 TMC5 DNAH7	3.69e-05	196	85	5	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP52 EPB41L4B SLC22A23 TMC5 DNAH7	3.69e-05	196	85	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D8 CFAP52 SYNE1 TMC5 DNAH7	3.78e-05	197	85	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D8 CFAP52 SYNE1 TMC5 DNAH7	3.78e-05	197	85	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE1 SYNE2 RNF213 EPB41	3.78e-05	197	85	5	4c9919914079e76b1d2220b249e0d0b0d9bf4bc0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 DOCK1 MYLK GPR37 FGFR2	3.78e-05	197	85	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D8 CFAP52 SYNE1 TMC5 DNAH7	3.78e-05	197	85	5	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC22A23 SYNE2 VEPH1 CHD7 MYO5C	3.78e-05	197	85	5	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D8 CFAP52 SYNE1 TMC5 DNAH7	3.78e-05	197	85	5	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE1 SYNE2 RNF213 SCAF11	3.87e-05	198	85	5	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 MYLK GPR37 FGFR2 PLEKHB1	3.87e-05	198	85	5	bdabdb11217ea16e5863aa6bfb0f04d48b17f81e
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPP6 VEPH1 FGFR2 TMC5 MYO5C	3.87e-05	198	85	5	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	CV\|World / Virus stimulation, Condition and Cluster	ARHGAP15 SYNE1 GNPTAB SYNE2 RNF213	3.87e-05	198	85	5	6a28193af35abec5c029129930c2ca6febaafde2
ToppCell	CD8+_Memory_T_cell-CV\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ARHGAP15 SYNE1 GNPTAB SYNE2 RNF213	3.87e-05	198	85	5	3d1749f5106f0912f4a74615863853949f52c73d
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DPP6 SLC22A23 SYNE2 VEPH1 MYO5C	3.87e-05	198	85	5	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GOLGA8IP SYNE1 GNPTAB SYNE2 RNF213	3.96e-05	199	85	5	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORT1 MYLK GPR37 FGFR2 PLEKHB1	3.96e-05	199	85	5	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP15 SYNE1 SYNE2 DEF6 EPB41	3.96e-05	199	85	5	9936196214a12502ebfaf152d39d40a2ed83c72d
Drug	NSC339663	DOCK1 PIKFYVE MYH2 MYLK SYNE1 SYNE2 CPSF2 MYO5C	3.34e-06	250	82	8	CID000003892
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	4.67e-05	4	83	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	7.77e-05	5	83	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	7.77e-05	5	83	2	C0410190
Disease	membrane-associated progesterone receptor component 2 measurement	PIKFYVE SARM1	7.77e-05	5	83	2	EFO_0801796
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.16e-04	6	83	2	cv:C0410189
Disease	E3 ubiquitin-protein ligase RNF128 measurement	PIKFYVE SARM1	1.16e-04	6	83	2	EFO_0801555
Disease	rab9 effector protein with kelch motifs measurement	PIKFYVE SARM1	1.16e-04	6	83	2	EFO_0801984
Disease	pappalysin-1 measurement	USP34 CHD7	1.16e-04	6	83	2	EFO_0802845
Disease	thioredoxin-interacting protein measurement	PIKFYVE SARM1	1.16e-04	6	83	2	EFO_0803149
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	1.16e-04	6	83	2	C0410189
Disease	secreted frizzled-related protein 2 measurement	PIKFYVE SARM1	1.16e-04	6	83	2	EFO_0802039
Disease	growth/differentiation factor 5 measurement	ANPEP SARM1	1.16e-04	6	83	2	EFO_0020429
Disease	unipolar depression	NBAS MYO1H PAFAH1B1 SYNE2 RNF213 YTHDC2 ELP2 CHD6 CHD7 HSD17B11 DDX21 DNAH7	1.37e-04	1206	83	12	EFO_0003761
Disease	CHARGE syndrome (implicated_via_orthology)	CHD6 CHD7	1.63e-04	7	83	2	DOID:0050834 (implicated_via_orthology)
Disease	myotubularin-related protein 1 measurement	PIKFYVE SARM1	1.63e-04	7	83	2	EFO_0802773
Disease	glycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement	SYNE2 CORIN	1.63e-04	7	83	2	EFO_0800551
Disease	kv channel-interacting protein 1 measurement	PIKFYVE SARM1	1.63e-04	7	83	2	EFO_0801751
Disease	RNA polymerase II elongation factor ELL measurement	PIKFYVE SARM1	1.63e-04	7	83	2	EFO_0802028
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.63e-04	7	83	2	C0751337
Disease	acid sphingomyelinase-like phosphodiesterase 3a measurement	GNPTAB SARM1	2.16e-04	8	83	2	EFO_0008013
Disease	growth factor receptor-bound protein 7 measurement	PIKFYVE SARM1	2.16e-04	8	83	2	EFO_0801659
Disease	health study participation	DPP6 TYW3 ARHGAP15 SLC22A23 TANGO6	2.29e-04	195	83	5	EFO_0010130
Disease	Drug habituation	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0013170
Disease	Drug abuse	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0013146
Disease	Prescription Drug Abuse	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C4316881
Disease	Substance-Related Disorders	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0236969
Disease	Drug Use Disorders	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0013222
Disease	Drug Dependence	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C1510472
Disease	Substance Dependence	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0038580
Disease	Substance Use Disorders	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	DOCK1 SYNE1 FHOD3 MYO5C	3.17e-04	115	83	4	C0029231
Disease	Substance abuse problem	DOCK1 SYNE1 FHOD3 MYO5C	3.28e-04	116	83	4	C0740858
Disease	transcription factor IIIb 90 kda subunit measurement	PIKFYVE SARM1	3.47e-04	10	83	2	EFO_0020778
Disease	OCIA domain-containing protein 1 measurement	PIKFYVE SARM1	3.47e-04	10	83	2	EFO_0008252
Disease	guanylate-binding protein 6 measurement	PIKFYVE SARM1	4.23e-04	11	83	2	EFO_0801662
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	5.07e-04	12	83	2	DOID:11726 (implicated_via_orthology)
Disease	phospholipids in medium HDL measurement	MYO1H SARM1 TECTB	5.07e-04	55	83	3	EFO_0022295
Disease	total lipids in medium HDL measurement	MYO1H SARM1 TECTB	5.92e-04	58	83	3	EFO_0022310
Disease	free cholesterol in medium HDL measurement	MYO1H SARM1 TECTB	5.92e-04	58	83	3	EFO_0022267
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	PIKFYVE SARM1	5.98e-04	13	83	2	EFO_0802114
Disease	Profound Mental Retardation	ELP2 FGFR2 TAF2 LARP7	6.50e-04	139	83	4	C0020796
Disease	Mental Retardation, Psychosocial	ELP2 FGFR2 TAF2 LARP7	6.50e-04	139	83	4	C0025363
Disease	Mental deficiency	ELP2 FGFR2 TAF2 LARP7	6.50e-04	139	83	4	C0917816
Disease	free cholesterol in HDL measurement	MYO1H LPA TECTB	6.87e-04	61	83	3	EFO_0022264
Disease	phospholipids in HDL measurement	MYO1H SARM1 TECTB	6.87e-04	61	83	3	EFO_0022293
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	GNA15 PLEKHB1	6.96e-04	14	83	2	EFO_0006830, EFO_0006896
Disease	total lipids in HDL measurement	MYO1H SARM1 TECTB	7.55e-04	63	83	3	EFO_0022307
Disease	amyotrophic lateral sclerosis	DOCK1 DPP6 TYW3 SARM1	7.61e-04	145	83	4	MONDO_0004976
Disease	ankle brachial index	NBAS LPA	9.14e-04	16	83	2	EFO_0003912
Disease	phospholipids in large HDL measurement	MYO1H LPA TECTB	1.16e-03	73	83	3	EFO_0022190
Disease	progression free survival, ovarian carcinoma	NBAS FHOD3	1.16e-03	18	83	2	EFO_0001075, EFO_0004920
Disease	BRCAX breast cancer	DOCK1 FGFR2	1.44e-03	20	83	2	EFO_0009443
Disease	Intellectual Disability	ATP8A2 SYNE1 ELP2 FGFR2 TAF2 LARP7	1.65e-03	447	83	6	C3714756
Disease	Immunologic Deficiency Syndromes	NBAS CHD7	1.90e-03	23	83	2	C0021051

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAAKKLWKVCVEHHT	EPB41	471	P11171
CKAKDAELAWIDGVL	CPSF2	621	Q9P2I0
HVVSVDKGCKAVLWA	ATG16L1	591	Q676U5
LLKWIDTTACLAAEK	ACOT12	31	Q8WYK0
DKLRAALACSKELWI	ANPEP	826	P15144
NIKDKPWHICASDAI	ARL6	151	Q9H0F7
WDINKHGLEETAAKC	HSD17B11	66	Q8NBQ5
LHCQWASIEDLEKDK	CHD7	836	Q9P2D1
DVAWRAAKHTCKKTL	ATP8A2	1086	Q9NTI2
ICDKKVFDLKDWELH	RBM20	416	Q5T481
ITCSKCDWLDGKHVV	PPIH	126	O43447
AKIIEKWINIAHECR	RGL1	306	Q9NZL6
LKVAAHLKWDLDILE	INTS8	86	Q75QN2
WVVATKECKAELREH	PAFAH1B1	261	P43034
RCLLKDAAVISWTKD	FGFR2	61	P21802
TVHWLRDGKALCKDT	MYLK	751	Q15746
DKLKFWTHCVLATLI	GNPTAB	1206	Q3T906
ELFATCAKKDIRVWH	CFAP52	346	Q8N1V2
DKDWAHISCAAKDLI	MKNK2	331	Q9HBH9
DKILAEWKQKCEETH	MYH2	1456	Q9UKX2
EKHAKALVGLWDSCL	VEPH1	76	Q14D04
VACYHELVLECTKKW	EHBP1L1	21	Q8N3D4
TEINKKHCWKLEILS	LARP7	511	Q4G0J3
RKKWIHCFENVIALI	GNA15	216	P30679
SKIKKRSWVLHECLE	NBAS	576	A2RRP1
DSVQLKDLWKKICHH	PIKFYVE	351	Q9Y2I7
HELTKKWLLEDFSCK	GPR37	321	O15354
LLHAKLLKWSEDVCV	DOCK1	1241	Q14185
LVICEWAALQKECKA	BTAF1	731	O14981
ELKKIHWSCVIIDEA	CHD6	586	Q8TD26
WHEDLKVILRKCAEG	DNAH7	2376	Q8WXX0
RCKASWDHLKAIAKH	FHOD3	1171	Q2V2M9
VLKETWTKHCDKAEL	C1GALT1C1L	86	P0DN25
ELVKKKELCFIHHWR	GOLGA8J	471	A6NMD2
KAEEGNHEWICRILK	ANKMY1	266	Q9P2S6
ISPEWVLTAAHCLKK	LPA	1851	P08519
HICGCVLIAKKWVLT	CORIN	826	Q9Y5Q5
VLIAKKWVLTVAHCF	CORIN	831	Q9Y5Q5
VKEHFDELCWTLTAK	DEF6	86	Q9H4E7
AELLHQCWEADAKKR	MAP3K20	236	Q9NYL2
ELVKKKELCFIHHWR	GOLGA8H	471	P0CJ92
HVKIEGKDTDDWLCV	MALSU1	156	Q96EH3
CKAAKKEHAAIILWN	ELP2	586	Q6IA86
KTAITVEHLAIKCHW	DDX21	406	Q9NR30
GVCTKKHEDESEAWL	DPP6	416	P42658
CHELKSFWEKEISKQ	FAM240B	16	A0A1B0GVZ2
AEKADCHEALLAAWK	DHX37	1111	Q8IY37
DLLSAKVCDLKWIHR	SCAF11	141	Q99590
DSARTCKHLWKCAVE	EPB41L4B	346	Q9H329
WEKLIAKAASIRDIC	FOCAD	581	Q5VW36
EVAHCAKSFALLKWL	TBRG4	331	Q969Z0
KICTWLEIKVHHVLL	TMEM106A	206	Q96A25
KVHWSLVVIDLRKKC	SENP2	476	Q9HC62
TCDLVALKLWVEKLS	SLITRK4	536	Q8IW52
EIHKAVCLAKWGSDN	SORT1	251	Q99523
VWLKDKEATHCKLCE	RUFY2	536	Q8WXA3
IIHWKCDIDVSKGAL	TOP6BL	16	Q8N6T0
KGVESLICTDWIRHK	MRPL30	21	Q8TCC3
FDKACHWLKQADIVT	SYNE1	4571	Q8NF91
EEKSRDVCAKWESLH	SYNE2	916	Q8WXH0
RAVAAKWKDDVIKLC	RLN1	21	P04808
LVCDNAWKVHIAKFS	SLC22A23	221	A1A5C7
LCIKVPSELWKHVDE	TAF2	126	Q6P1X5
SVDLCGAHIEWAKEK	ARHGAP15	136	Q53QZ3
TKLVAHACWAIKELD	CCT8L1P	181	A6NM43
TKLVAHACWAIKELD	CCT8L2	181	Q96SF2
KLSKVWLHCETFICD	TECTB	256	Q96PL2
CEVLFKVHKFWLTED	SNTG2	351	Q9NY99
EQAHEWVKCIAKAFV	ARAP1	836	Q96P48
ELHKLAKRCWHSLLS	TP53TG5	61	Q9Y2B4
LCAWVEKFINVKAHH	RNF213	3191	Q63HN8
KDWVHKEIVTALSCG	SARM1	636	Q6SZW1
LHLCAETKDDALAWK	PLEKHB1	106	Q9UF11
ELLVCDWCKHIRHTK	SOBP	221	A7XYQ1
KEKLHAVVDCSLWTP	TBC1D8	296	O95759
EVTAADWKKCDLIAK	TANGO6	341	Q9C0B7
VEVKCWEQLLEDKHF	WDR6	376	Q9NNW5
HLDWCLEGDSIKVKS	SPRTN	471	Q9H040
VLLKWCAHTNVELKK	PRKDC	296	P78527
LKLATTILQHWKKCD	PRKDC	1616	P78527
IKEMDACLSDIWLHK	YTHDC2	466	Q9H6S0
CWDFTVTHEKAVKLK	TMC5	571	Q6UXY8
WLLCKLVDNIHIKDA	USP34	1736	Q70CQ2
CWLLVTHKLCVKDDV	TYW3	71	Q6IPR3
ELVKKKELCFIHHWR	GOLGA8IP	471	A6NC78
CATIPDTHEIKWIAK	MYO1H	291	Q8N1T3
KEAWAAIIIQKHCRG	MYO5C	806	Q9NQX4