Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCyt_P450_E_grp-I_CYP1

CYP1A1 CYP1A2

4.16e-0521212IPR008066
Domain-

TRAF7 GEMIN5 BIRC6 LYST SEMA4C NBEAL2 TLE4 MLST8 BTRC WDTC1

6.24e-05333121102.130.10.10
DomainWD40/YVTN_repeat-like_dom

TRAF7 GEMIN5 BIRC6 LYST SEMA4C NBEAL2 TLE4 MLST8 BTRC WDTC1

6.56e-0533512110IPR015943
DomainPTPc

PTPN23 PTPN18 PTPRT PTPRN2

8.41e-05361214SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN23 PTPN18 PTPRT PTPRN2

1.16e-04391214PS50055
DomainPTPase_domain

PTPN23 PTPN18 PTPRT PTPRN2

1.41e-04411214IPR000242
DomainY_phosphatase

PTPN23 PTPN18 PTPRT PTPRN2

1.41e-04411214PF00102
DomainWD40

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

2.87e-042591218PF00400
DomainWD40

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

3.60e-042681218SM00320
DomainWD40_repeat

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

3.98e-042721218IPR001680
DomainTPR-contain_dom

PTPN23 TMTC1 TANC1 EDRF1 TTC33 WDTC1

4.37e-041501216IPR013026
DomainWD_REPEATS_1

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

4.59e-042781218PS00678
DomainWD_REPEATS_2

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

4.70e-042791218PS50082
DomainWD_REPEATS_REGION

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

4.70e-042791218PS50294
DomainPTPc_motif

PTPN23 PTPN18 PTPRT PTPRN2

5.79e-04591214SM00404
DomainTyr_Pase_cat

PTPN23 PTPN18 PTPRT PTPRN2

5.79e-04591214IPR003595
DomainPH_BEACH

LYST NBEAL2

6.14e-0461212PF14844
DomainWD40_repeat_CS

TRAF7 GEMIN5 LYST TLE4 MLST8 BTRC

7.00e-041641216IPR019775
DomainWD40_repeat_dom

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

7.09e-042971218IPR017986
DomainTPR_REGION

PTPN23 TMTC1 TANC1 EDRF1 TTC33 WDTC1

7.22e-041651216PS50293
DomainTPR

PTPN23 TMTC1 TANC1 EDRF1 TTC33 WDTC1

7.22e-041651216PS50005
DomainTIG

RELB CAMTA2 EBF1

1.04e-03311213PF01833
DomainPH-BEACH_dom

LYST NBEAL2

1.14e-0381212IPR023362
Domain-

LYST NBEAL2

1.14e-03812122.30.29.40
DomainPH_BEACH

LYST NBEAL2

1.14e-0381212PS51783
DomainIPT

RELB CAMTA2 EBF1

1.15e-03321213IPR002909
DomainTyr_Pase_AS

PTPN23 PTPN18 PTPRT PTPRN2

1.29e-03731214IPR016130
DomainBEACH

LYST NBEAL2

1.45e-0391212PS50197
DomainBeach

LYST NBEAL2

1.45e-0391212PF02138
Domain-

LYST NBEAL2

1.45e-03912121.10.1540.10
DomainBeach

LYST NBEAL2

1.45e-0391212SM01026
DomainBEACH_dom

LYST NBEAL2

1.45e-0391212IPR000409
DomainDNA/RNA_helicase_DEAH_CS

DHX37 DHX30 CHD5

1.49e-03351213IPR002464
DomainPkinase_Tyr

PDGFRB TXK IGF1R GUCY2D MAP3K10

1.53e-031291215PF07714
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

TRAF7 GALR1 GRM7 PTPRT IGF1R PTPRN2 GLI2 GUCY2D

1.96e-07171124820201926
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MPO ILF2 AGO2 ACAT2 MAP4K3 DHX37 GEMIN5 PTPN23 NDUFA9 BIRC6 DHX30 LONP1 MDN1 GTF3C1 G3BP1 NCAPD2 TANC1 BTRC DCP1A

3.38e-0713531241929467282
Pubmed

Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.

MPO CYP1A1 CYP1A2

8.78e-076124319479063
Pubmed

Tagging genes with cassette-exchange sites.

AGO2 MAP4K3 XPO4 GEMIN5 BIRC6 DHX30 GLI2 TANC1 ZMYM4

3.45e-06335124915741177
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ATXN2L ILF2 DHX37 GEMIN5 BIRC6 DHX30 LONP1 MDN1 GTF3C1 G3BP1 NUP210 NCAPD2

4.08e-066531241222586326
Pubmed

Defining the membrane proteome of NK cells.

ATXN2L ILF2 AGO2 ABI3 PDGFRB CCDC126 GEMIN5 BIRC6 LONP1 MDN1 GTF3C1 NBEAL2 CHD5 NUP210 NCAPD2 DCP1A

4.28e-0611681241619946888
Pubmed

Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population.

MPO CYP1A1 CYP1A2

5.21e-0610124318784359
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

AGO2 XPO4 PTPN23 STAM PTPN18 BIRC6 PTPRT CEMIP2 LONP1 PTPRN2 NUP210 TANC1 BTRC DCP1A TTC33

5.25e-0610491241527880917
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ATXN2L ILF2 AGO2 ABI3 WASHC1 SYT6 DHX30 CADPS BTRC DCP1A

8.37e-064751241031040226
Pubmed

Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.

CYP1A1 CYP1A2

1.26e-05212422425809
Pubmed

Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.

CYP1A1 CYP1A2

1.26e-05212423000715
Pubmed

Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.

CYP1A1 CYP1A2

1.26e-052124212147246
Pubmed

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.

CYP1A1 CYP1A2

1.26e-052124217852022
Pubmed

Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.

CYP1A1 CYP1A2

1.26e-052124214980704
Pubmed

Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues.

CYP1A1 CYP1A2

1.26e-05212427781742
Pubmed

Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.

CYP1A1 CYP1A2

1.26e-052124211207026
Pubmed

Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.

CYP1A1 CYP1A2

1.26e-05212423785172
Pubmed

Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.

CYP1A1 CYP1A2

1.26e-05212423860967
Pubmed

Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.

CYP1A1 CYP1A2

1.26e-052124216609368
Pubmed

GLI2 induces PDGFRB expression and modulates cancer stem cell properties of gastric cancer.

PDGFRB GLI2

1.26e-052124228975979
Pubmed

Serum starvation and growth factor receptor expression in vascular smooth muscle cells.

PDGFRB IGF1R

1.26e-052124216407661
Pubmed

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

CYP1A1 CYP1A2

1.26e-052124215094312
Pubmed

CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.

CYP1A1 CYP1A2

1.26e-052124219285097
Pubmed

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation.

TBX10 TBX1

1.26e-052124215703190
Pubmed

[Association of polymorph variants of CYP1A2 and CYP1A1 genes with reproductive and thyroid diseases in female workers of petrochemical industry].

CYP1A1 CYP1A2

1.26e-052124222855999
Pubmed

Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.

CYP1A1 CYP1A2

1.26e-052124212438513
Pubmed

Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.

CYP1A1 CYP1A2

1.26e-052124221262253
Pubmed

Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.

CYP1A1 CYP1A2

1.26e-052124226953171
Pubmed

Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

CYP1A1 CYP1A2

1.26e-052124218493746
Pubmed

Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.

CYP1A1 CYP1A2

1.26e-052124232726451
Pubmed

A shuffled CYP1A library shows both structural integrity and functional diversity.

CYP1A1 CYP1A2

1.26e-052124217823232
Pubmed

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.

CYP1A1 CYP1A2

1.26e-05212423988744
Pubmed

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.

CYP1A1 CYP1A2

1.26e-052124226643992
Pubmed

Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.

CYP1A1 CYP1A2

1.26e-052124222949628
Pubmed

Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.

CYP1A1 CYP1A2

1.26e-05212429295056
Pubmed

Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.

CYP1A1 CYP1A2

1.26e-052124225680282
Pubmed

EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications.

PDGFRB EBF1

1.26e-052124226872634
Pubmed

Chromosomal mapping of genes involved in growth control.

PDGFRB IGF1R

1.26e-05212423107886
Pubmed

Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.

CYP1A1 CYP1A2

1.26e-052124225703676
Pubmed

Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.

CYP1A1 CYP1A2

1.26e-05212424054433
Pubmed

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.

CYP1A1 CYP1A2

1.26e-052124231147315
Pubmed

Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.

CYP1A1 CYP1A2

1.26e-05212428001243
Pubmed

Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco.

CYP1A1 CYP1A2

1.26e-052124216402549
Pubmed

The effect of CYP1A1 and CYP1A2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.

CYP1A1 CYP1A2

1.26e-052124224443269
Pubmed

Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.

CYP1A1 CYP1A2

1.26e-052124216426572
Pubmed

The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population.

CYP1A1 CYP1A2

1.26e-052124233046100
Pubmed

Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis.

PDGFRB EBF1

1.26e-052124228555080
Pubmed

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

MPO CP

1.26e-05212429097926
Pubmed

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment.

PDGFRB EBF1

1.26e-052124233626861
Pubmed

CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.

CYP1A1 CYP1A2

1.26e-052124219276377
Pubmed

Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

CYP1A1 CYP1A2

1.26e-052124217052995
Pubmed

Differences in regulation of gene expression between Cyp1a-1 and Cyp1a-2 in adult mouse hepatocytes in primary culture.

CYP1A1 CYP1A2

1.26e-05212421335375
Pubmed

Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.

CYP1A1 CYP1A2

1.26e-05212428095225
Pubmed

A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.

CYP1A1 CYP1A2

1.26e-052124216505155
Pubmed

Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.

CYP1A1 CYP1A2

1.26e-05212428274012
Pubmed

Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.

MPO CP

1.26e-052124223306200
Pubmed

Species difference among experimental rodents in induction of P450IA family enzymes by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

CYP1A1 CYP1A2

1.26e-05212421452456
Pubmed

Amino-terminal sequence and structure of monoclonal antibody immunopurified cytochromes P-450.

CYP1A1 CYP1A2

1.26e-05212423718958
Pubmed

Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.

CYP1A1 CYP1A2

1.26e-052124214637164
Pubmed

Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment.

CYP1A1 CYP1A2

1.26e-052124216516144
Pubmed

Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other.

MPO CP

1.26e-052124219031316
Pubmed

Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.

CYP1A1 CYP1A2

1.26e-052124228698457
Pubmed

[Association of cytochrome P450 genes polymorphisms (CYP1A1 and CYP1A2) with the development of chronic obstructive pulmonary disease in Bashkortostan].

CYP1A1 CYP1A2

1.26e-052124218389617
Pubmed

Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450.

CYP1A1 CYP1A2

1.26e-05212426548461
Pubmed

Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer.

CYP1A1 CYP1A2

1.26e-052124234242741
Pubmed

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.

CYP1A1 CYP1A2

1.26e-052124210623596
Pubmed

Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.

CYP1A1 CYP1A2

1.26e-052124221081470
Pubmed

Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.

MPO CYP1A1 CYP1A2

1.95e-0515124318632753
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

PDGFRB MUC16 PTPN18 PTPRT CEMIP2 LONP1 IGF1R G3BP1 ZMYM4

2.09e-05420124928065597
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CTTNBP2 XPO4 SRCIN1 SEMA4C TANC1

3.36e-05102124511214970
Pubmed

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.

ATXN2L ILF2 AGO2 G3BP1

3.65e-0552124426265008
Pubmed

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

CYP1A1 CYP1A2

3.77e-053124217997381
Pubmed

Ataxin-2-like is a regulator of stress granules and processing bodies.

ATXN2L G3BP1

3.77e-053124223209657
Pubmed

CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD.

CYP1A1 CYP1A2

3.77e-053124220080081
Pubmed

Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss.

CYP1A1 CYP1A2

3.77e-053124215299091
Pubmed

Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer.

CYP1A1 CYP1A2

3.77e-053124215734958
Pubmed

Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.

CYP1A1 CYP1A2

3.77e-053124224668907
Pubmed

Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of colorectal cancer: a hospital-based case-control study in Japan.

CYP1A1 CYP1A2

3.77e-053124219452301
Pubmed

Meat intake, metabolic genes and colorectal cancer.

CYP1A1 CYP1A2

3.77e-053124212484238
Pubmed

Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1.

CYP1A1 CYP1A2

3.77e-053124238081439
Pubmed

Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.

CYP1A1 CYP1A2

3.77e-053124224497629
Pubmed

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.

CYP1A1 CYP1A2

3.77e-053124219666078
Pubmed

Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.

CYP1A1 CYP1A2

3.77e-053124218814841
Pubmed

Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways.

CYP1A1 CYP1A2

3.77e-053124223956430
Pubmed

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.

CYP1A1 CYP1A2

3.77e-053124221357676
Pubmed

Adenomyosis: genetics of estrogen metabolism.

CYP1A1 CYP1A2

3.77e-053124230878995
Pubmed

Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1.

CYP1A1 CYP1A2

3.77e-053124223353840
Pubmed

Genetic polymorphism of estrogen metabolizing enzymes in Siberian women with breast cancer.

CYP1A1 CYP1A2

3.77e-053124221977969
Pubmed

Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells.

CYP1A1 CYP1A2

3.77e-053124228245756
Pubmed

Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.

CYP1A1 CYP1A2

3.77e-053124218372398
Pubmed

Regulation of cytochrome P-450 isozymes CYP1A1, CYP1A2 and CYP2B10 by three benzodioxole compounds.

CYP1A1 CYP1A2

3.77e-05312427750163
Pubmed

Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.

CYP1A1 CYP1A2

3.77e-053124224349309
Pubmed

Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan.

CYP1A1 CYP1A2

3.77e-053124220047124
Pubmed

CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation.

AGO2 BTRC

3.77e-053124219647520
Pubmed

Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption.

CYP1A1 CYP1A2

3.77e-053124222854411
Pubmed

Utility of Nicotiana tabacum cell suspension cultures expressing human CYP1A1, CYP1A2 and CYP3A4 to study the oxidative metabolism of the herbicide 14C-fluometuron.

CYP1A1 CYP1A2

3.77e-053124219356113
Pubmed

Phorbol esters inhibit the dioxin receptor-mediated transcriptional activation of the mouse Cyp1a-1 and Cyp1a-2 genes by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

CYP1A1 CYP1A2

3.77e-05312421313028
Pubmed

Correlations between ceruloplasmin, lactoferrin and myeloperoxidase in meconium.

MPO CP

3.77e-053124227903408
Pubmed

In situ hybridization of Cyp1a1, Cyp1a2 and Ah receptor mRNAs expressed in murine ocular tissues.

CYP1A1 CYP1A2

3.77e-05312428795463
Pubmed

Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells.

PDGFRB IGF1R

3.77e-053124217568996
CytobandEnsembl 112 genes in cytogenetic band chr3p21

COL7A1 PTPN23 DHX30 UBA7 NBEAL2 DCP1A

2.29e-043161246chr3p21
GeneFamilyWD repeat domain containing

TRAF7 GEMIN5 LYST NBEAL2 TLE4 MLST8 BTRC WDTC1

3.80e-05262878362
GeneFamilyCytochrome P450 family 1

CYP1A1 CYP1A2

1.36e-0448721000
GeneFamilyWD repeat domain containing|BEACH domain containing

LYST NBEAL2

8.06e-0498721230
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TMTC1 TANC1 TTC33 WDTC1

2.30e-03115874769
GeneFamilyDEAH-box helicases

DHX37 DHX30

2.63e-0316872500
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN23 PTPN18

3.33e-0318872812
GeneFamilyCD molecules|Integrin alpha subunits

ITGA10 ITGA2B

3.33e-03188721160
GeneFamilyT-boxes

TBX10 TBX1

3.33e-0318872766
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRT PTPRN2

4.53e-0321872813
GeneFamilyLipases|Arylacetamide deacetylase family

CEL LIPK

4.97e-0322872464
CoexpressionGSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP

TRAF7 MICAL1 ZNF618 XPO4 RELB PTPN18 NBEAL2 TLE4

4.45e-061961248M7973
CoexpressionGSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP

MAP4K3 LYST ADORA1 TLE4 GUCY2D ALAS2 TANC1 BTRC

4.97e-061991248M3599
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSTN3 CEL CP ATP10B GRM7 AQP4 SEC14L3 ADORA1 TBX1

2.01e-091811239092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSTN3 CP ATP10B AQP4 SEC14L3 ADORA1 TBX1

3.31e-071611237c4970501c038ed36de447da70eabff020ad78713
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLSTN3 CP ATP10B AQP4 SEC14L3 ADORA1 TBX1

3.31e-07161123741a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CTTNBP2 PDGFRB CP EBF1 GRM7 GLI2 TLE4

6.76e-071791237e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYT6 ADORA1 C1QL2 CADPS CHD5 SULT4A1 PNOC

7.01e-0718012377d3d5608647b6e684e8e185993d106a38c53e76a
ToppCellMonocytes-Inflammatory_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

ABI3 LYST CFD TMTC1 MIDN NBEAL2 TLE4

1.16e-06194123728d19105123b015f8aa25ea8e6c078f630d4ba80
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

ABI3 LYST TBC1D8 CFD TMTC1 MIDN KDM1B

1.24e-061961237af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCSK5 ABI3 CEMIP2 TXK BPGM GTF3C1 KLHDC4

1.28e-061971237c7cd7960e8f022b1db49485ff153675827efa35e
ToppCellHealthy-Non-classical_Monocyte|Healthy / disease group, cell group and cell class

ABI3 PHTF2 LYST TBC1D8 CFD TMTC1 KDM1B

1.33e-061981237394e5fa8998c46c6f7cd57b53f347d2029c75ae1
ToppCellwk_08-11-Epithelial-Proximal_epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

INHBB MUC16 CP NPDC1 CFAP65 CADPS QPCT

1.33e-0619812379895f1d65d18d939f3974a914ee41c6d5575e765
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZNF618 PTPRT CEMIP2 PTPRN2 CADPS CHD5 PNOC

1.42e-062001237c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellBLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PCSK5 ABI3 PDGFRB CEMIP2 BPGM GTF3C1

3.15e-0614512366dd81d53d006fcc206a10969374a11c372f92133
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 KLHL11 BPGM GUCY2D ALAS2

4.10e-068612351f44bb41835445aa60a2e3c31616c5847447a246
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 ADORA1 TMTC1

5.75e-0616112361b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellfacs-Heart-LV-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO CEL SEC14L3 PTPRN2 ALAS2 PLAAT5

6.17e-061631236648d5439811b64412bc4678646f216105b90b9a1
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGO2 GEMIN5 CHD5 ALAS2 MLST8 ZMYM4

6.17e-061631236953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

OR11G2 PDGFRB GATA3 PHTF2 EBF1 TMTC1

6.39e-061641236f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellTuft-tuft-4|World / Class top

LIPK ADORA1 KLHL11 MDN1 PTPRN2 EDRF1

8.97e-061741236d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1 CADPS

9.27e-0617512361b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

PCSK5 INHBB MAP4K3 SRCIN1 CEMIP2 MAP3K10

9.89e-061771236b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NAGK ABI3 LYST CFD TMTC1 MIDN

1.39e-0518812363e94d105ca96ceb5fdcca39a8050217913bc02da
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 PDGFRB SYT6 ITGA10 ACOT12 TMTC1

1.39e-051881236ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GALR1 INHBB CFAP65 CADPS QPCT TBX1

1.48e-0519012362375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

ABI3 LYST TXK IGF1R GTF3C1 KLHDC4

1.48e-0519012361584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CLSTN3 PTPRN2 CADPS CHD5 SULT4A1 PNOC

1.52e-0519112365d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CLSTN3 PTPRN2 CADPS CHD5 SULT4A1 PNOC

1.52e-05191123673dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

INHBB CFAP65 CADPS QPCT TBX10 TBX1

1.57e-0519212364d3a1c267739b1479217144656986972fc86db43
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLSTN3 PTPRN2 CADPS CHD5 LRRC7 SULT4A1

1.62e-051931236461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLSTN3 PTPRN2 CADPS CHD5 LRRC7 SULT4A1

1.62e-0519312360dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.66e-0519412361b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCellhealthy_donor-Myeloid-Monocytic-CD16+_Monocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.66e-051941236ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB CP EBF1 CFD TMTC1 GLI2

1.66e-051941236c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

INHBB NPDC1 CFAP65 NUP210 QPCT TBX10

1.66e-051941236ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

ABI3 PDGFRB CEMIP2 TXK BPGM GTF3C1

1.71e-051951236e756733cf48768bf40058d6cf9039e52f7563133
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GALR1 CEL SYT6 PTPRN2 CADPS CHD5

1.76e-0519612364bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellControl-Non-classical_Monocyte-|Control / Disease condition and Cell class

ABI3 PHTF2 LYST TBC1D8 CFD TMTC1

1.76e-051961236b17ab094cdc7050c2997e24ed474779b5d6f6146
ToppCellT_cells-CD56_dim_CD16+_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ABI3 PDGFRB PTPN18 TXK BPGM TLE4

1.76e-05196123607b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCellControl-Non-classical_Monocyte|Control / Disease condition and Cell class

ABI3 PHTF2 LYST TBC1D8 CFD TMTC1

1.76e-051961236404064ccfe2cb73df7a7f88aa65d86b97dcef9d4
ToppCellCOVID-19_Severe-Non-classical_Monocyte|World / disease group, cell group and cell class

LYST TBC1D8 CFD TMTC1 MIDN KDM1B

1.81e-05197123660fee75b12451206bb2c07b61651a73c59ec6ade
ToppCellControl-Epithelial_alveolar-AT_2-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CP CFAP65 MLST8 TBX1 PLAAT5

1.85e-051171235c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCellremission-Non-classical_Monocyte|World / disease stage, cell group and cell class

NAGK ABI3 LYST CFD TMTC1 KDM1B

1.87e-0519812361c170655070acca00520b7cf9c510a04c0a90a8f
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-051981236cbbdd44dfa95370c0fbaa65ba71d86bfee0ea379
ToppCellmild_COVID-19_(asymptomatic)-NK|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ABI3 PDGFRB CEMIP2 TXK GTF3C1 KLHDC4

1.87e-0519812361e43181c13e054570046c7a973ddc1c586e259b0
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-0519812363bc3dbd178043deadd7eef413b2761dc003abd6e
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-0519812369b47585653aaebd033c9b7bba93c7a7c35a4d60e
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NAGK ABI3 LYST TBC1D8 CFD MIDN

1.87e-051981236ad8d4ad042f06fd1afbaef903fb36e57e4d23a7c
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-0519812368b5d30312bbcabc6911ff03e5028766d77203dff
ToppCellHealthy-Non-classical_Monocyte|World / disease group, cell group and cell class

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-0519812364fd27a9fb3758c94ed9f0a726296e92b0625da44
ToppCellControl-Myeloid-Non-classical_Monocyte|Control / Disease group, lineage and cell class

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-051981236ae0a51e63e2751a6d9dc0c8a3852680949173523
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-0519812367d8fade2583c07a33dd83057cbce08e9fc77987a
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.87e-051981236165d60b111a17d517a420c434733eefb98da240d
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A|356C / Donor, Lineage, Cell class and subclass (all cells)

PCSK5 ABI3 CEMIP2 TXK BPGM GTF3C1

1.92e-051991236868412bbd8a203f3e9369fb6dc09791c07023496
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

ITGA10 SRCIN1 AQP4 PTPRT CHD5 ALAS2

1.97e-05200123661d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ABI3 PHTF2 LYST TBC1D8 CFD KDM1B

1.97e-052001236334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellControl-Control-Myeloid-CD16+_Monocyte|Control / Disease, condition lineage and cell class

ABI3 LYST TBC1D8 CFD TMTC1 KDM1B

1.97e-0520012368dd124a5aca897652ea68efbfc5a167b4cf31aef
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 XIRP1 ABI3 TXK GUCY2D

4.68e-051421235e5608bbbc04edcdaafe1affc4db7f9d8edba04d9
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 MC3R ADORA1 TMTC1 TLE4

6.07e-0515012352ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 GALR1 GATA3 FANCF CHD5

6.26e-0515112353744e4ed87703a97002e001afd16490d525a5128
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

PDGFRB PCDHGA11 SYT6 EBF1 RUSC2

6.26e-0515112358ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 ZWILCH ZNF618 ZFP69 BPGM

6.46e-051521235655d47efe0608d729801f1f01668e84c1bc0675f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB EBF1 ACOT12 TMTC1 CADPS

6.87e-0515412353211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB EBF1 ACOT12 TMTC1 CADPS

6.87e-051541235c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB EBF1 ACOT12 TMTC1 CADPS

6.87e-0515412354c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCellfacs-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 SEMA4C TXK TMTC1 QPCT

7.53e-051571235a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCellHippocampus-Endothelial-MURAL|Hippocampus / BrainAtlas - Mouse McCarroll V32

XIRP1 PDGFRB ITGA10 EBF1 KBTBD13

7.76e-0515812352d73b5e59c650c603fec6223b1c51f0962f7bc81
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCSK5 ABI3 INHBB ME3 BPGM

7.76e-0515812351bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

XIRP1 PDGFRB ITGA10 EBF1 KBTBD13

7.76e-0515812357f4a644534b78f7e7539cae1fd895dad6f96862b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

7.99e-0515912355ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CA12 OR11G2 CCDC126 PTPRN2 QPCT

8.23e-051601235913e59cecf3b1bdd1ef32b4e320042b9bbdb54bc
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

BIRC6 CEMIP2 SEC14L3 MDN1 ALAS2

8.48e-0516112351973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellControl-Epithelial-Ionocyte|Control / Disease state, Lineage and Cell class

DDX12P MUC16 SEC14L3 IGF2BP2-AS1 PLAAT5

8.98e-051631235bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 GRM7 CEMIP2 ME3 KLHL11

8.98e-0516312357a04192710f55acf5a4681d5f09942358fdb02ff
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYT6 ME3 ADORA1 TLE4 QPCT

8.98e-051631235b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP4 PTPN23 RELB KLHDC4 ZMYM4

8.98e-051631235a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

9.25e-051641235b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BPGM NUP210 ALAS2 TBX1

9.50e-058612344d20625cb666cd09509e07e8db527b94b379509a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

9.52e-051651235e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

9.52e-051651235b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

9.52e-051651235d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SRCIN1 AQP4 ADORA1 ZMYM4 TBX1

9.79e-0516612352e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

SRCIN1 AQP4 ADORA1 ZMYM4 TBX1

9.79e-051661235eb8d972326a734549675307e411fc795af66da70
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 NPDC1 ADORA1 TMTC1

1.01e-041671235b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 NPDC1 ADORA1 TMTC1

1.01e-04167123594fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 NPDC1 ADORA1 TMTC1

1.01e-041671235eff3723fe60755272eca237459165e436e919ece
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYT6 SRCIN1 PTPN18 PTPRT TLE4

1.04e-0416812358072d0496b7b730c4601009eaa69ec5366d26d73
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGB6 MAP4K3 CHD5 GUCY2D ALAS2

1.06e-0416912354e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EBF1 BPGM PTPRN2 GLI2 ALAS2

1.06e-041691235c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

1.09e-041701235876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

1.09e-0417012351f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC66A2 XPO4 SRCIN1 ZFP69 QPCT

1.13e-0417112353d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

1.16e-04172123508a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

PDGFRB LYST TXK BPGM GTF3C1

1.16e-041721235701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRB GATA3 PHTF2 EBF1 TMTC1

1.16e-041721235553701349444eb366df3c11f54bb093434f153c6
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGB6 PCDHGA11 EBF1 ME3 TMTC1

1.22e-041741235268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGB6 PCDHGA11 EBF1 ME3 TMTC1

1.22e-0417412354cdf2eedc28d88d18241ee390092426fdf849e79
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDGFRB GATA3 PHTF2 EBF1 TMTC1

1.22e-0417412358393f0b43c767839c1630bcb952d62b42efc788d
ToppCellfacs-MAT-Fat-3m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B CFD BPGM ALAS2

1.29e-04931234dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCellfacs-MAT-Fat-3m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B CFD BPGM ALAS2

1.29e-049312340d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCellfacs-MAT-Fat-3m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B CFD BPGM ALAS2

1.29e-04931234abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

CTTNBP2 ZNF618 PTPRN2 LRRC7 SULT4A1

1.29e-041761235d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

CA12 CYP1A1 MICAL1 RELB CAMTA2 RUSC2 FOCAD NBEAL2 QPCT EDRF1

7.76e-08188123103281_UP
DrugLisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CA12 ATXN2L COL7A1 CAMTA2 RUSC2 TLE4 SULT4A1 BTRC WDTC1

1.27e-0619712391545_DN
Drug2-nitrofluorene

CYP1A1 CYP1A2 RELB EBF1 BTRC

4.87e-06461235CID000011831
Drugestradiol-17 beta benzoate

MPO BIRC6 IGF1R PNOC

5.50e-06221234CID000066420
Drug3-aminobenzanthrone

MPO CYP1A1 CYP1A2

8.45e-0681233ctd:C475568
DrugH-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A

ATXN2L CEL RELB ITGA2B PTPN18 RUSC2 SEMA4C UBA7

1.11e-0519512386873_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; PC3; HT_HG-U133A

CYP1A1 ATXN2L COL7A1 RELB PTPRN2 GLI2 EDRF1 TBX1

1.20e-0519712384433_UP
DrugPropidium iodide [25535-16-4]; Up 200; 6uM; PC3; HT_HG-U133A

CYP1A1 ATXN2L GATA3 ITGA2B ADORA1 IGF1R BTRC TBX1

1.20e-0519712385803_UP
Drug7-hydroxyflavone

CYP1A1 CYP1A2 CFD

1.26e-0591233CID005281894
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A

CYP1A2 MICAL1 CAMTA2 PTPN18 LYST SEMA4C IGF1R NUP210

1.34e-0520012385842_DN
DrugAC1NTIMC

CYP1A1 CYP1A2 QPCT

2.46e-05111233CID005381912
Drughomoeriodictyol

CYP1A1 CYP1A2 LYST

2.46e-05111233CID000073635
DrugNSC-522175

CP CFD

2.89e-0521232CID000437590
Drug2-methoxy-4-aminoazobenzene

CYP1A1 CYP1A2

2.89e-0521232ctd:C053767
DrugAC1NNGYV

CEL QPCT

2.89e-0521232CID005043460
Drug3,4,3',4'-tetrachloroazoxybenzene

CYP1A1 CYP1A2

2.89e-0521232ctd:C013280
Drugcloflucarban

CYP1A1 CYP1A2

2.89e-0521232ctd:C005055
Drugmusk xylene

CYP1A1 CYP1A2

2.89e-0521232ctd:C031447
Drug1-O-hexyl-2,3,5-trimethylhydroquinone

MPO CYP1A2

2.89e-0521232ctd:C081906
Drugsesamex

CYP1A1 CYP1A2

2.89e-0521232ctd:C100180
DrugCanthaxanthin

CYP1A1 CYP1A2

2.89e-0521232ctd:D016644
DrugPigment Yellow 74

CYP1A1 CYP1A2

2.89e-0521232CID000022829
Drugpyridoxal isonicotinoyl hydrazone

CYP1A1 CYP1A2

2.89e-0521232ctd:C021079
Drugnitroaniline

CYP1A1 CYP1A2

2.89e-0521232ctd:C008625
Drug7H-dibenzo(c,g)carbazole

CYP1A1 CYP1A2

2.89e-0521232ctd:C013478
Drug2,7-dinitrofluorene

CYP1A1 CYP1A2

2.89e-0521232ctd:C085049
Drugbeta-apo-8'-carotenal

CYP1A1 CYP1A2

2.89e-0521232ctd:C110652
Drugpropachlor

CYP1A1 CYP1A2

2.89e-0521232ctd:C011088
Drugallocryptopine

CYP1A1 CYP1A2

2.89e-0521232ctd:C109505
Drug2,7-FAA

CYP1A1 CYP1A2

2.89e-0521232CID000009352
Drugprotopine

CYP1A1 CYP1A2

2.89e-0521232ctd:C009093
Drugflumecinol

CYP1A1 INHBB CFD

3.27e-05121233CID000041870
Drug3,4-dichlorophenol

CYP1A1 CYP1A2 CEL

3.27e-05121233CID000007258
Drug4-nitroaniline

MPO CYP1A1 CYP1A2

4.23e-05131233ctd:C019498
Drugcompound 22

PDGFRB ADORA1 QPCT PNOC

5.19e-05381234CID000205101
Drug2-methyl-6-styrylpyridine

CYP1A2 GRM7 ADORA1

5.36e-05141233CID000235382
Drug2-naphthol

CYP1A1 CYP1A2 SULT4A1

6.68e-05151233ctd:C028405
Drug1-Naphthylisothiocyanate

MPO CYP1A1 CYP1A2 NAGK PDGFRB ACAT2 GATA3 CCDC126 CP NPDC1 ITGA2B PTPN18 CEMIP2 ADORA1 CFD

7.29e-0587112315ctd:D015058
Drugdesmethylazelastine

CYP1A1 CYP1A2 PTPRN2

8.18e-05161233CID000162558
DrugAmodiaquine

MPO CYP1A1 CYP1A2

8.18e-05161233ctd:D000655
Drug2-aminofluorene

MPO CYP1A1 CYP1A2

8.18e-05161233ctd:C012177
DrugCP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A

CLSTN3 GATA3 ITGA2B SEMA4C PTPRN2 BTRC TBX1

8.19e-0519112373823_DN
DrugJ 113397

MPO PNOC

8.65e-0531232ctd:C402921
Drug2,3-diaminotoluene

CYP1A1 CYP1A2

8.65e-0531232ctd:C100420
Drug2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine

CYP1A1 CYP1A2

8.65e-0531232ctd:C522525
DrugB746

MPO LYST

8.65e-0531232CID000122674
Drug2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline

CYP1A1 CYP1A2

8.65e-0531232ctd:C519626
Drugscutellarein

CYP1A1 CYP1A2

8.65e-0531232ctd:C458179
Druggenkwanin

CYP1A1 CYP1A2

8.65e-0531232ctd:C014568
Drug1-methoxyrutaecarpine

CYP1A1 CYP1A2

8.65e-0531232CID005319487
DrugSuppressor Factors, Immunologic

CYP1A1 CYP1A2

8.65e-0531232ctd:D013491
Drugalyssin

CYP1A1 CYP1A2

8.65e-0531232ctd:C524316
Drug2-oxohexyl isothiocyanate

CYP1A1 CYP1A2

8.65e-0531232ctd:C524315
DrugTrichloroepoxypropane

CYP1A1 CYP1A2

8.65e-0531232ctd:D014239
Drug8-phenyltheophylline

CYP1A2 ADORA1

8.65e-0531232ctd:C028322
Drug3-aminofluorene

CYP1A1 CYP1A2

8.65e-0531232CID000022818
Drug1-aminofluorene

CYP1A1 CYP1A2

8.65e-0531232CID000022817
Drug2,2',4,6'-tetramethoxystilbene

CYP1A1 CYP1A2

8.65e-0531232ctd:C541980
Drug6-nitrobenzo(a)pyrene

CYP1A1 CYP1A2

8.65e-0531232ctd:C034699
Drugchlortoluron

CYP1A1 CYP1A2

8.65e-0531232ctd:C007033
DrugAminoquinolines

CYP1A1 CYP1A2

8.65e-0531232ctd:D000634
Drug7-(deoxyadenosin-N(6)--yl)aristolactam II

CYP1A1 CYP1A2

8.65e-0531232ctd:C405699
Drug1,2,3,7,8-pentachlorodibenzofuran

CYP1A1 CYP1A2

8.65e-0531232ctd:C057584
Drug7-nitrobenzanthracene

CYP1A1 CYP1A2

8.65e-0531232ctd:C038954
Drug1,2-dichloroethylene

CYP1A1 CYP1A2

8.65e-0531232ctd:C035384
DrugAC1L9FX4

MPO CEL BIRC6 LYST

9.32e-05441234CID000444209
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

CYP1A2 INHBB RELB CAMTA2 PTPN18 RUSC2 TBX10

9.33e-0519512377255_UP
DrugAzacyclonol [115-46-8]; Down 200; 15uM; MCF7; HT_HG-U133A

ITGA10 PHTF2 PHKA2 CFD NUP210 SULT4A1 WDTC1

9.33e-0519512371520_DN
DrugAlfadolone acetate [23930-37-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A

CA12 CYP1A2 CEL LYST CFD BTRC EDRF1

9.63e-0519612376506_DN
DrugEpicatechin-(-) [154-23-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

CYP1A2 ATXN2L CEL GATA3 RUSC2 SEMA4C TBX10

9.63e-0519612374594_DN
DrugCromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; PC3; HT_HG-U133A

CYP1A2 PHTF2 CAMTA2 CEMIP2 PHKA2 GLI2 SULT4A1

9.63e-0519612375754_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A

COL7A1 PHTF2 GRM7 PTPRN2 NBEAL2 TLE4 TBX1

9.63e-0519612374319_UP
DrugIproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

CA12 MICAL1 PHTF2 UBA7 TBX10 BTRC EDRF1

9.63e-0519612372288_DN
DrugN-(3-(aminomethyl)benzyl)acetamidine

MPO CYP1A1 CYP1A2

9.90e-05171233ctd:C104820
Drug3-amino-1-methyl-5H-pyrido(4,3-b)indole

MPO CYP1A1 CYP1A2

9.90e-05171233ctd:C019133
Drug2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A

CYP1A1 ATXN2L CLSTN3 RELB PTPRN2 GLI2 SULT4A1

1.03e-0419812374446_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PCSK5 ATXN2L RELB ITGA2B ADORA1 GLI2 CHD5

1.03e-0419812374358_UP
DrugC75; Up 200; 10uM; PC3; HT_HG-U133A

CA12 CAMTA2 PHKA2 PTPRN2 BTRC TBX1 TTC33

1.03e-0419812376428_UP
DrugDeoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

MXRA5 MC3R ATP10B GRM7 ADORA1 CHD5 SULT4A1

1.03e-0419812376476_UP
DrugPiperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A

CA12 ATXN2L MICAL1 CAMTA2 CFD SULT4A1 BTRC

1.03e-0419812373551_DN
DrugPivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

CYP1A2 PHTF2 RUSC2 NUP210 SULT4A1 BTRC WDTC1

1.06e-0419912373535_DN
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A

ATXN2L PHTF2 PTPN18 LYST NBEAL2 SULT4A1 WDTC1

1.06e-0419912375540_UP
DrugLevopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A

CA12 ATXN2L PHTF2 RUSC2 NUP210 BTRC WDTC1

1.06e-0419912373543_DN
DrugGanciclovir [82410-32-0]; Up 200; 15.6uM; HL60; HT_HG-U133A

CA12 PCSK5 PCDHGB6 AQP4 ADORA1 IGF1R PTPRN2

1.09e-0420012373030_UP
DrugFlorfenicol [73231-34-2]; Up 200; 11.2uM; PC3; HT_HG-U133A

ATXN2L COL7A1 CLSTN3 ITGA2B AQP4 SEMA4C BTRC

1.09e-0420012376701_UP
Drug1-benzylimidazole

CYP1A1 CYP1A2 QPCT ALAS2

1.31e-04481234CID000077918
Drugpantoprazole

MPO CYP1A1 CYP1A2

1.40e-04191233ctd:C064276
Drugcholest-4-en-3-on

CEL PDGFRB SULT4A1

1.40e-04191233CID000000440
DrugDB04649

MPO GALR1 CFD IGF1R QPCT SULT4A1

1.55e-041481236CID005287847
DrugDomperidone

MPO CYP1A1 CYP1A2

1.64e-04201233ctd:D004294
Drug1-chloropyrene

CYP1A1 CYP1A2

1.72e-0441232ctd:C040345
Drugpurpurin

CYP1A1 CYP1A2

1.72e-0441232ctd:C511975
Drug2-nitrofluoranthene

CYP1A1 CYP1A2

1.72e-0441232ctd:C049030
Drug7-methoxyresorufin

CYP1A1 CYP1A2

1.72e-0441232ctd:C076580
Drug2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester

CYP1A1 CYP1A2

1.72e-0441232ctd:C520611
Drugmusk ketone

CYP1A1 CYP1A2

1.72e-0441232ctd:C031448
Drug3,6-dinitrobenzopyrene

CYP1A1 CYP1A2

1.72e-0441232ctd:C068923
DrugPY74

CYP1A1 CYP1A2

1.72e-0441232CID000017893
DrugN-methyl-7H-dibenzo(c,g)carbazole

CYP1A1 CYP1A2

1.72e-0441232ctd:C041150
Drugterbutryne

CYP1A1 CYP1A2

1.72e-0441232ctd:C010347
DiseaseColorectal Carcinoma

MPO CYP1A2 COL7A1 CLSTN3 SLC66A2 STAM PTPRT ADORA1 PTPRN2 CHD5 EDRF1 ZMYM4 TBX1

8.54e-0670212413C0009402
Disease5-hydroxy-2-methylpyridine sulfate measurement

CYP1A1 CYP1A2

1.75e-0521242EFO_0801051
Diseaseserum clozapine measurement

CYP1A1 CYP1A2

1.75e-0521242EFO_0600041
Diseasehypoparathyroidism (is_implicated_in)

GATA3 TBX1

5.24e-0531242DOID:11199 (is_implicated_in)
DiseaseX-21286 measurement

CYP1A1 CYP1A2

1.05e-0441242EFO_0800804
Diseaseporphyria cutanea tarda (is_implicated_in)

CYP1A1 CYP1A2

2.60e-0461242DOID:3132 (is_implicated_in)
Diseaseplasma clozapine measurement

CYP1A1 CYP1A2

4.82e-0481242EFO_0600038
Diseaseadvanced glycation end-product measurement

CYP1A1 CYP1A2

6.19e-0491242EFO_0007819
Diseaseepilepsy (is_implicated_in)

CP TBX1

6.19e-0491242DOID:1826 (is_implicated_in)
DiseaseInhalant adrenergic use measurement

GATA3 MUC16 ATP10B CHADL

7.32e-04961244EFO_0009941
Diseasehydroxyproline measurement

CA12 PTPRT

7.71e-04101242EFO_0010498
Diseasetheophylline measurement

CYP1A1 CYP1A2

7.71e-04101242EFO_0021180
Diseasesweet beverage consumption measurement

CYP1A1 CYP1A2

7.71e-04101242EFO_0010090
Disease1,7-dimethylurate measurement

CYP1A1 CYP1A2

7.71e-04101242EFO_0021512
Disease1-methylxanthine measurement

CYP1A1 CYP1A2

9.40e-04111242EFO_0021174
Diseaseplasma N-desmethylclozapine measurement

CYP1A1 CYP1A2

9.40e-04111242EFO_0600039
Disease5-acetylamino-6-amino-3-methyluracil measurement

CYP1A1 CYP1A2

9.40e-04111242EFO_0800951
DiseaseOccupational Diseases

MPO CYP1A1

9.40e-04111242C0028797
Diseaseparaxanthine measurement

CYP1A1 CYP1A2

1.12e-03121242EFO_0021178
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

AQP4 IGF1R

1.33e-03131242DOID:332 (biomarker_via_orthology)
Diseasecalcium measurement

ZWILCH INHBB MAP4K3 GATA3 PHTF2 SEMA4C PTPRN2 TLE4 QPCT

1.37e-036281249EFO_0004838
Diseaseserum urea measurement

CYP1A1 CYP1A2 EBF1 IGF1R TTC33

1.43e-031951245EFO_0009795
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

TBX10 TBX1

1.54e-03141242DOID:0060413 (implicated_via_orthology)
Diseaseunipolar depression, anxiety

CLDN24 LRRC7

1.54e-03141242EFO_0003761, EFO_0005230
Diseaserenal cell carcinoma (biomarker_via_orthology)

CYP1A1 IGF1R

1.54e-03141242DOID:4450 (biomarker_via_orthology)
DiseaseKuhnt-Junius degeneration (is_marker_for)

PDGFRB IGF1R

1.54e-03141242DOID:10873 (is_marker_for)
Disease1,3,7-trimethylurate measurement

CYP1A1 CYP1A2

1.77e-03151242EFO_0021172
Diseaselysophosphatidylethanolamine 18:0 measurement

ABI3 TMTC1

1.77e-03151242EFO_0010367
DiseaseAlobar Holoprosencephaly

GLI2 DISP1

1.77e-03151242C0431363
Diseasepuberty onset measurement

INHBB MC3R BIRC6 IGF1R

1.95e-031251244EFO_0005677
DiseaseLobar Holoprosencephaly

GLI2 DISP1

2.02e-03161242C0431362
Diseasecoffee consumption, cups of coffee per day measurement

CYP1A1 CYP1A2

2.02e-03161242EFO_0004330, EFO_0006782
DiseaseSemilobar Holoprosencephaly

GLI2 DISP1

2.02e-03161242C0751617
DiseaseHoloprosencephaly

GLI2 DISP1

2.29e-03171242C0079541
Diseaseheart disease (biomarker_via_orthology)

CYP1A1 CP

2.29e-03171242DOID:114 (biomarker_via_orthology)
Diseasecaffeine metabolite measurement

CYP1A1 CYP1A2

2.86e-03191242EFO_0007872
DiseaseCocaine Dependence

AGO2 GALR1 SRCIN1 LRRC7

2.86e-031391244C0600427
Diseasetotal blood protein measurement

CLSTN3 MAP4K3 ZNF618 PHTF2 EBF1 CEMIP2 TLE4

2.95e-034491247EFO_0004536
Diseaseblood urea nitrogen measurement

CYP1A1 CYP1A2 PHTF2 EBF1 IGF1R TANC1 TTC33

3.06e-034521247EFO_0004741
Diseaselymphocyte count

GALR1 CEL PCDHGB6 PCDHGA11 GATA3 NPDC1 EBF1 LYST PTPRT ME3 FOCAD BPGM TLE4 QPCT

3.43e-03146412414EFO_0004587
DiseaseLung Injury

CYP1A1 CYP1A2

3.49e-03211242C0273115
DiseaseChronic Lung Injury

CYP1A1 CYP1A2

3.49e-03211242C2350344
Diseaseinterleukin 18 measurement

PTPN18 BIRC6 PTPRT

4.07e-03761243EFO_0004581
Diseaseobsolete Mendelian syndromes with cleft lip/palate

GRM7 LRRC7

4.18e-03231242MONDO_0015335
DiseaseMorbilliform Drug Reaction

MPO CYP1A1

4.18e-03231242C0406537
DiseaseDrug Eruptions

MPO CYP1A1

4.18e-03231242C0011609

Protein segments in the cluster

PeptideGeneStartEntry
PGHAMADTYAVVQKR

PTPN18

346

Q99952
HLFAINYTGASMNPA

AQP4

201

P55087
HAPLALGHYAVAQMQ

CLDN24

191

A6NM45
RINATSHVIQHPMYG

BIRC6

3836

Q9NR09
QHVAYMNTLRFATPG

CLSTN3

591

Q9BQT9
LRRAAYLNMTQDPNH

CHD5

1806

Q8TDI0
YIAIFLTHGNSAMNP

ADORA1

271

P30542
LTHGNSAMNPIVYAF

ADORA1

276

P30542
QGVYAPLHSMNDLRV

COQ3

111

Q9NZJ6
GHINSYLKPMLQRDF

BTRC

166

Q9Y297
GMSLLHLAAAQGYAR

CAMTA2

711

O94983
NHMSASILPYFAGNL

ACOT12

511

Q8WYK0
GLVDRNNEPLTHAMY

DHX30

316

Q7L2E3
ANLPGNYGLRDQHMA

CEL

176

P19835
ASPYHGFTIVNRLNM

DCP1A

61

Q9NPI6
NLGMPVHAAYNSELS

DISP1

1226

Q96F81
HLLGPNRIMAYSRGQ

ATP10B

1426

O94823
SPVFEGVYNNSRMLH

ATXN2L

111

Q8WWM7
IAAVVGSMDAHPNRY

AGO2

611

Q9UKV8
RHIGHLLPMDYSANA

NAGK

321

Q9UJ70
SPGSYAARQHIMQRI

QPCT

81

Q16769
SLVGSNMFPNHYREA

RELB

551

Q01201
GKNPHLALSRMSQQY

CYP1A1

56

P04798
PHLALSRMSQRYGDV

CYP1A2

61

P05177
MGLSARYGPQFTLQH

PCDHGA11

876

Q9Y5H2
HYLQSRVPMGSGQEA

PTPN23

76

Q9H3S7
HLMAALSAYAAQRPP

PTPRN2

241

Q92932
MGLSARYGPQFTLQH

PCDHGB6

871

Q9Y5F9
VAYQVGNLAGHTLRM

ABI3

61

Q9P2A4
NMATRPYSIHAHGVQ

CP

826

P00450
ARPYMASVQLNGAHL

CFD

36

P00746
AYQEARGVAMVHPLL

NUP210

936

Q8TEM1
PISQFYADRAQKHGM

CADPS

651

Q9ULU8
TNLQYEENMGHPGSR

MUC16

13176

Q8WXI7
SHNLPGLFDYARQMQ

MAP4K3

626

Q8IVH8
VQVARGMNYLHNDAP

MAP3K10

201

Q02779
QHLANDGYMLLAGRV

MDN1

1296

Q9NU22
SAVHMLRFNGYRENP

FANCF

141

Q9NPI8
EMFPAAQQLYRHGKA

JAGN1

121

Q8N5M9
YMVASGLPQRNGQRH

GUCY2D

931

Q02846
NAAYKHNTVNLGMLP

LRRC7

1286

Q96NW7
RHPQIIASANYMLSE

EDRF1

496

Q3B7T1
ANPAATTHYMLRLVG

CFAP65

971

Q6ZU64
HTAVVNQYRMRGLNP

INHBB

351

P09529
PSDMHIQGLQSRYSA

CA12

101

O43570
YAHMNGGRKNERALP

IGF1R

1346

P08069
TPDRSMIAAAGYQHI

MLST8

51

Q9BVC4
RTHPDLMQNYDALAS

PCSK5

176

Q92824
LNMQRSRDHGLPGYN

MPO

586

P05164
ARAFLMQHAPANDYL

LONP1

821

P36776
MHRNVAQYGLDPATR

MICAL1

451

Q8TDZ2
QQLAYARATGHAMAA

GLI2

1391

P10070
HYGALIGLNREQMAL

BPGM

91

P07738
NHLGRMGSQVIIPYR

NDUFA9

71

Q16795
SNDYLGMSRHPQVLQ

ALAS2

196

P22557
AAALYQPRASEMQHL

PNOC

81

Q13519
NMARPQDGYRIVQHL

PTPRT

1321

O14522
VYLLRAMVVHGGSQP

IGF2BP2-AS1

101

Q96M15
SPGDQRLAQSAEMYH

NPDC1

236

Q9NQX5
ALSIAMASPVAYHQG

GALR1

161

P47211
ACGLYHKMNGQNRPL

GATA3

286

P23771
SHVSLLPRYGQNMDV

KLHL11

346

Q9NVR0
AALSVHVPGMNRYFQ

KDM1B

256

Q8NB78
LLLQAAPRGAAHYEM

C1QL2

11

Q7Z5L3
GLMLLHYTFQQPRHQ

CCDC126

26

Q96EE4
LLMYHRIPAHGNSFN

CTTNBP2

861

Q8WZ74
TLLNQAPDMLHRFYG

G3BP1

21

Q13283
DLLGHYAVMNNPTRQ

ILF2

246

Q12905
LPYQMLLHAATRQAA

DDX12P

386

Q92771
GRMDNYLIRHPSCVN

CEMIP2

966

Q9UHN6
RAADLVEALYGMPHN

EBF1

381

Q9UH73
KHAGRSFNDLMQYPV

LYST

3151

Q99698
TYGQTPRQLFHMAHV

LYST

3406

Q99698
LAVVRNGNLHSPMYF

MC3R

61

P41968
YDVTRNPHLNKGMAF

ME3

51

Q16798
AQRIAAASMPHALSY

ITGA10

596

O75578
PRSNAMLAVKHGVLY

KLHDC4

431

Q8TBB5
AARGQEMYAPHSIRI

GRM7

31

Q14831
GNNLGTAVVTAHRYM

COL7A1

1131

Q02388
LEGPQTHANRIYRMN

HSP90AA4P

366

Q58FG1
AHNALVYLPAMAFQG

CHADL

166

Q6NUI6
APRYAKMLALSRQHG

DHX37

781

Q8IY37
GEMTDVLPSQRYNAH

SEC14L3

331

Q9UDX4
KQRPYQHGADMLAAI

FOCAD

596

Q5VW36
NMNLSGRPYRHIGVL

PHKA2

491

P46019
AIKRGYRMAQPAHAS

PDGFRB

916

P09619
QRLHAPMYILLANFS

OR11G2

91

Q8NGC1
PHVMGSARLQQLAGY

OTOG

236

Q6ZRI0
NDLLSATRHYQGMPP

MIDN

311

Q504T8
ATRHYQGMPPSLAQL

MIDN

316

Q504T8
TLYNKMHGTPRANLN

RUSC2

286

Q8N2Y8
RQMHVSSVDYGNELP

SYT6

181

Q5T7P8
IMNRVNSHIPGIGYQ

PHTF2

486

Q8N3S3
HQARGMSLQSNYLGL

FNBP4

851

Q8N3X1
SNAAGVMHYLIRVEP

NBEAL2

2161

Q6ZNJ1
PRNGHALLAFMFSRQ

TANC1

836

Q9C0D5
AVHLPQGAHYMRALS

ITGA2B

681

P08514
ALVVMAAQPRHAGAY

SEMA4C

611

Q9C0C4
AAFRAQGPLAMLQHF

NCAPD2

46

Q15021
NGHIILNSMHRYQPR

TBX10

181

O75333
SKAVQRAPHNAMLYG

WDTC1

386

Q8N5D0
RAPHNAMLYGNRAAA

WDTC1

391

Q8N5D0
ARQLIGLYTMAHNPN

ZWILCH

106

Q9H900
GNFNTLALKHLPRMY

ZNF618

516

Q5T7W0
PNLGRHYIAMFESSQ

XPO4

241

Q9C0E2
SPSHHVAMVNLGRLY

TMTC1

646

Q8IUR5
NMSKAPHLAYLRTGV

ACAT2

121

Q9BWD1
LHNGDSKVIYMARNP

SULT4A1

121

Q9BR01
YPQHALALRGQQDRM

SRCIN1

91

Q9C0H9
AANLYAQMHGLPGSQ

UBA7

731

P41226
AAYAGLHNISPQMSA

TLE4

391

Q04727
MVAHRDSLYVVRNGP

KBTBD13

346

C9JR72
AHRNPKIGYCQSMNI

TBC1D8

581

O95759
MQHSLAGQTYAVPFI

WASHC1

6

A8K0Z3
TDNLVAMAPAAGYHV

GEMIN5

946

Q8TEQ6
SHINARLNMGILGSY

TRAF7

366

Q6Q0C0
SGAYLVAGNAQMSHL

STAM

411

Q92783
HQHNAAGLMTRLRYP

TXK

231

P42681
RYGVPRSQQVEHALM

PLAAT5

241

Q96KN8
NGHIILNSMHRYQPR

TBX1

226

O43435
KPAQASHTNYLLMRG

GTF3C1

1636

Q12789
SPVYAMQDSKGRLHA

XIRP1

481

Q702N8
TEAMLGVPQLYRNHR

SLC66A2

181

Q8N2U9
AIPQYHLAMSDGSIR

ZMYM4

586

Q5VZL5
GQLAPAHQNLYREVM

ZFP69

91

Q49AA0
AIRSFQVALHIYPMN

TTC33

146

Q6PID6
NMSRLDVYLSHNPAG

LIPK

271

Q5VXJ0
DLANTSHVYMLPNGT

MXRA5

621

Q9NR99