Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lipid transporter activity	TNFAIP8L3 PSG4 ABCA12 PSG9 SLCO4A1 ABCA7 SLCO1C1 ABCA6 PLEKHA8	1.08e-05	196	141	9	GO:0005319
GeneOntologyMolecularFunction	transporter activity	CACNA1S TRPV1 TNFAIP8L3 PSG4 ABCA12 PSG9 SLCO4A1 NMUR2 ABCA7 CACNG7 SLCO1C1 ABCA6 KCNC3 SLC15A2 SLC45A3 KCNJ14 SLC25A53 HTR3D CACNA1H ABCC12 ATP1A2 UNC80 PLEKHA8	3.50e-05	1289	141	23	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1S TRPV1 PSG4 ABCA12 PSG9 SLCO4A1 NMUR2 ABCA7 CACNG7 SLCO1C1 ABCA6 KCNC3 SLC15A2 SLC45A3 KCNJ14 SLC25A53 HTR3D CACNA1H ABCC12 ATP1A2 UNC80	8.30e-05	1180	141	21	GO:0022857
GeneOntologyMolecularFunction	phospholipid binding	RAG2 TRPV1 TNFAIP8L3 SYT3 PSG4 PSG9 PLA2G4E CPNE5 IGHM DNM1 UNC13A PLEKHA8 PCYT1B	1.40e-04	548	141	13	GO:0005543
GeneOntologyMolecularFunction	A1 adenosine receptor binding	P2RY1 P2RY2	1.48e-04	3	141	2	GO:0031686
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	PSG4 ABCA12 PSG9 SLCO4A1 SLCO1C1	1.67e-04	73	141	5	GO:0170055
GeneOntologyMolecularFunction	tRNA (cytidine-3-)-methyltransferase activity	METTL2A METTL2B	2.94e-04	4	141	2	GO:0052735
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1S TRPV1 CACNG7 CACNA1H	3.09e-04	46	141	4	GO:0005245
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA12 ABCA7 ABCA6 ABCC12	3.94e-04	49	141	4	GO:0140359
GeneOntologyMolecularFunction	phosphatidylinositol binding	RAG2 TRPV1 TNFAIP8L3 SYT3 PSG4 PSG9 PLA2G4E DNM1 PLEKHA8	4.19e-04	316	141	9	GO:0035091
GeneOntologyMolecularFunction	lipid binding	RAG2 TRPV1 TNFAIP8L3 SYT3 GPER1 PSG4 PSG9 PLA2G4E CPNE5 MVB12A NFE2L1 IGHM ATP1A2 DNM1 UNC13A PLEKHA8 PCYT1B	6.10e-04	988	141	17	GO:0008289
GeneOntologyMolecularFunction	histone H4K20 monomethyltransferase activity	KMT5B PRDM6	7.29e-04	6	141	2	GO:0140944
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1S TRPV1 CACNG7 KCNC3 KCNJ14 CACNA1H	7.43e-04	152	141	6	GO:0022843
GeneOntologyMolecularFunction	steroid hormone binding	GPER1 ATP1A2	1.02e-03	7	141	2	GO:1990239
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA12 ABCA7 ABCA6 ABCC12 ATP1A2	1.06e-03	109	141	5	GO:0042626
GeneOntologyMolecularFunction	chemorepellent activity	SEMA6C FLRT3 SEMA4A	1.10e-03	29	141	3	GO:0045499
GeneOntologyMolecularFunction	calmodulin binding	CACNA1S TRPV1 PSG4 PSG9 PHKB MYO15A UNC13A	1.26e-03	230	141	7	GO:0005516
GeneOntologyMolecularFunction	adenosine receptor binding	P2RY1 P2RY2	1.35e-03	8	141	2	GO:0031685
GeneOntologyBiologicalProcess	import into cell	CACNA1S TRPV1 DNAJC13 ANK3 BMP2K PSG4 PSG9 ICAM3 CFP ABCA7 CACNG7 LRP10 KCNC3 SLC15A2 IGHM KCNJ14 CACNA1H C4BPA ATP1A2 DNM1 MYO15A AP3D1	3.80e-06	1074	141	22	GO:0098657
GeneOntologyBiologicalProcess	neuron projection extension	SEMA6C FN1 SYT3 TTC3 CPNE5 CACNG7 FLRT3 FLRT1 UNC13A	1.29e-05	207	141	9	GO:1990138
GeneOntologyBiologicalProcess	positive regulation of dendrite extension	SYT3 CPNE5 CACNG7 UNC13A	5.70e-05	31	141	4	GO:1903861
GeneOntologyBiologicalProcess	regulation of dendrite extension	SYT3 CPNE5 CACNG7 UNC13A	9.29e-05	35	141	4	GO:1903859
GeneOntologyBiologicalProcess	lipid localization	ZC3H12A TNFAIP8L3 PSG4 ABCA12 PSG9 SLCO4A1 NMUR2 ABCA7 SLCO1C1 LRP10 ABCA6 P2RY2 PLEKHA8	1.37e-04	565	141	13	GO:0010876
GeneOntologyBiologicalProcess	cellular response to alkaloid	CACNA1S TRPV1 MDM2 CRHBP	1.58e-04	40	141	4	GO:0071312
GeneOntologyBiologicalProcess	endocytosis	DNAJC13 ANK3 BMP2K PSG4 PSG9 ICAM3 CFP ABCA7 CACNG7 LRP10 KCNC3 IGHM C4BPA DNM1 MYO15A AP3D1	1.73e-04	827	141	16	GO:0006897
GeneOntologyBiologicalProcess	lipid transport	TNFAIP8L3 PSG4 ABCA12 PSG9 SLCO4A1 NMUR2 ABCA7 SLCO1C1 LRP10 ABCA6 P2RY2 PLEKHA8	1.90e-04	506	141	12	GO:0006869
GeneOntologyBiologicalProcess	regulation of vesicle-mediated transport	MBTPS1 DNAJC13 ANK3 SYT3 BMP2K CFP PLA2G4E ABCA7 P2RY1 KCNC3 P2RY2 IGHM CACNA1H DNM1	1.97e-04	667	141	14	GO:0060627
GeneOntologyBiologicalProcess	positive regulation of intracellular signal transduction	DHX36 HGF ZC3H12A TNFAIP8L3 FN1 RNF31 ANK3 ERN1 GPER1 PSG4 PSG9 NMUR2 F2RL2 ABCA7 TGFBR3 CSNK1A1L GBP5 P2RY1 CSNK1A1 IGHM CORO7	2.01e-04	1299	141	21	GO:1902533
GeneOntologyBiologicalProcess	regulation of NLRP3 inflammasome complex assembly	TRIM31 CSNK1A1L GBP5 CSNK1A1	2.10e-04	43	141	4	GO:1900225
GeneOntologyBiologicalProcess	developmental growth involved in morphogenesis	SEMA6C FN1 SYT3 TTC3 CPNE5 CACNG7 FLRT3 FLRT1 UNC13A	2.21e-04	299	141	9	GO:0060560
GeneOntologyBiologicalProcess	developmental cell growth	SEMA6C FN1 SYT3 TTC3 CPNE5 CACNG7 FLRT3 FLRT1 UNC13A	2.32e-04	301	141	9	GO:0048588
GeneOntologyBiologicalProcess	regulation of cell morphogenesis	DHX36 FN1 SYT3 CPNE5 CACNG7 P2RY1 IGHM SEMA4A UNC13A	2.38e-04	302	141	9	GO:0022604
GeneOntologyBiologicalProcess	dendrite extension	SYT3 CPNE5 CACNG7 UNC13A	2.73e-04	46	141	4	GO:0097484
GeneOntologyBiologicalProcess	NLRP3 inflammasome complex assembly	TRIM31 CSNK1A1L GBP5 CSNK1A1	2.73e-04	46	141	4	GO:0044546
GeneOntologyBiologicalProcess	pre-B cell allelic exclusion	RAG2 IGHM	2.76e-04	4	141	2	GO:0002331
GeneOntologyBiologicalProcess	negative regulation of NLRP3 inflammasome complex assembly	TRIM31 CSNK1A1L CSNK1A1	2.80e-04	19	141	3	GO:1900226
GeneOntologyCellularComponent	synaptic membrane	TRPV1 ANK3 SYT3 GPER1 TENM2 CACNG7 P2RY1 KCNC3 P2RY2 HTR3D CACNA1H FLRT3 DNM1 UNC13A SEZ6L	9.66e-06	583	141	15	GO:0097060
GeneOntologyCellularComponent	postsynaptic membrane	TRPV1 ANK3 GPER1 TENM2 CACNG7 P2RY1 KCNC3 HTR3D CACNA1H FLRT3 SEZ6L	9.75e-05	405	141	11	GO:0045211
GeneOntologyCellularComponent	dendritic spine membrane	TRPV1 GPER1 KCNC3	2.28e-04	18	141	3	GO:0032591
GeneOntologyCellularComponent	presynaptic active zone	GPER1 PPFIBP1 P2RY1 P2RY2 CACNA1H UNC13A	3.93e-04	141	141	6	GO:0048786
GeneOntologyCellularComponent	postsynapse	CACNA1S TRPV1 ANK3 SYT3 GPER1 TENM2 CACNG7 P2RY1 KCNC3 HTR3D CACNA1H FLRT3 ATP1A2 AP3D1 SEZ6L SEZ6 KPNA2	5.11e-04	1018	141	17	GO:0098794
GeneOntologyCellularComponent	cell body	DHX36 TRPV1 GPER1 CPNE5 CRHBP CACNG7 P2RY1 KCNC3 KCNJ14 CACNA1H C4BPA FLRT1 ATP1A2 SEZ6L HDAC1 SEZ6	5.41e-04	929	141	16	GO:0044297
GeneOntologyCellularComponent	neuron projection terminus	GPER1 CRHBP KCNC3 FLRT3 FLRT1 AP3D1 UNC13A	1.04e-03	233	141	7	GO:0044306
GeneOntologyCellularComponent	cation channel complex	CACNA1S CACNG7 KCNC3 KCNJ14 HTR3D CACNA1H UNC80	1.10e-03	235	141	7	GO:0034703
GeneOntologyCellularComponent	Golgi membrane	MBTPS1 GPER1 ABCA12 CFP ABCA7 QSOX1 GBP5 ABCA6 HS6ST1 CORO7 AP3D1 PLEKHA8 KPNA2	1.21e-03	721	141	13	GO:0000139
GeneOntologyCellularComponent	dendritic spine	CACNA1S TRPV1 GPER1 TENM2 KCNC3 ATP1A2 SEZ6	1.30e-03	242	141	7	GO:0043197
GeneOntologyCellularComponent	neuron spine	CACNA1S TRPV1 GPER1 TENM2 KCNC3 ATP1A2 SEZ6	1.46e-03	247	141	7	GO:0044309
GeneOntologyCellularComponent	somatodendritic compartment	DHX36 CACNA1S TRPV1 ANK3 GPER1 CPNE5 TENM2 CRHBP CACNG7 P2RY1 KCNC3 KCNJ14 CACNA1H FLRT1 ATP1A2 SEZ6L HDAC1 SEZ6	1.56e-03	1228	141	18	GO:0036477
GeneOntologyCellularComponent	neuronal cell body	DHX36 TRPV1 GPER1 CPNE5 CRHBP CACNG7 KCNC3 KCNJ14 CACNA1H FLRT1 ATP1A2 SEZ6L HDAC1 SEZ6	1.56e-03	835	141	14	GO:0043025
Domain	-	CSMD3 CRHBP LRP10 SEZ6L SEZ6	4.93e-05	52	144	5	2.60.120.290
Domain	CUB_dom	CSMD3 CRHBP LRP10 SEZ6L SEZ6	7.71e-05	57	144	5	IPR000859
Domain	ABC_A	ABCA12 ABCA7 ABCA6	9.38e-05	12	144	3	IPR026082
Domain	DUF4599	SPATA31D4 SPATA31D1 SPATA31D3	9.38e-05	12	144	3	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D1 SPATA31D3	9.38e-05	12	144	3	IPR027970
Domain	MeTrfase	METTL2A METTL2B	3.51e-04	4	144	2	IPR026113
Domain	ABC_tran	ABCA12 ABCA7 ABCA6 ABCC12	5.07e-04	48	144	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCA12 ABCA7 ABCA6 ABCC12	5.07e-04	48	144	4	PS50893
Domain	CUB	CSMD3 LRP10 SEZ6L SEZ6	5.49e-04	49	144	4	PF00431
Domain	ABC_TRANSPORTER_1	ABCA12 ABCA7 ABCA6 ABCC12	5.49e-04	49	144	4	PS00211
Domain	ABC_transporter-like	ABCA12 ABCA7 ABCA6 ABCC12	5.93e-04	50	144	4	IPR003439
Domain	CUB	CSMD3 LRP10 SEZ6L SEZ6	5.93e-04	50	144	4	SM00042
Domain	Sushi	CSMD3 C4BPA SEZ6L SEZ6	6.88e-04	52	144	4	PF00084
Domain	CUB	CSMD3 LRP10 SEZ6L SEZ6	7.40e-04	53	144	4	PS01180
Domain	CCP	CSMD3 C4BPA SEZ6L SEZ6	7.95e-04	54	144	4	SM00032
Domain	PUB_domain	RNF31 ERN1	8.68e-04	6	144	2	IPR018997
Domain	Methyltransf_12	METTL2A METTL2B	8.68e-04	6	144	2	IPR013217
Domain	Methyltransf_12	METTL2A METTL2B	8.68e-04	6	144	2	PF08242
Domain	SUSHI	CSMD3 C4BPA SEZ6L SEZ6	9.12e-04	56	144	4	PS50923
Domain	Sushi_SCR_CCP_dom	CSMD3 C4BPA SEZ6L SEZ6	9.75e-04	57	144	4	IPR000436
Pubmed	P2Y1, P2Y2, and TRPV1 Receptors Are Increased in Diarrhea-Predominant Irritable Bowel Syndrome and P2Y2 Correlates with Abdominal Pain.	TRPV1 P2RY1 P2RY2	6.95e-08	3	144	3	27250983
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DHX36 PDE3B ATN1 RNF31 PPFIBP1 SLCO4A1 DHX57 MAP3K6 ELP2 DNM1 HSD17B4 AP3D1 TOP3A	3.39e-06	650	144	13	38777146
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	FN1 SYT3 DHX57 SMG5 ACAD10 MDH2 PHKB CSNK1A1L CSNK1A1 HSD17B4 AP3D1	5.04e-06	475	144	11	31040226
Pubmed	MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.	MBTPS1 FN1 FBN2	5.73e-06	9	144	3	25652402
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	MBTPS1 FN1 MDM2 HS6ST1	8.13e-06	31	144	4	11431694
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA12 ABCA6 ABCC12	8.17e-06	10	144	3	11435397
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM2 FLRT3 FLRT1	8.17e-06	10	144	3	38713721
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FN1 VASN ICAM3 CFP LGALS3BP QSOX1 C4BPA BCAM	1.26e-05	257	144	8	16335952
Pubmed	Peli1 Modulates the Subcellular Localization and Activity of Mdmx.	MDM2 CSNK1A1L CSNK1A1	1.49e-05	12	144	3	29523541
Pubmed	Yeast Two-Hybrid Screening for Proteins that Interact with the Extracellular Domain of Amyloid Precursor Protein.	FLRT3 FLRT1 SEZ6L	1.49e-05	12	144	3	26960425
Pubmed	Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2.	TRPV1 P2RY2	1.70e-05	2	144	2	18343036
Pubmed	Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	23354688
Pubmed	Co-activation of P2Y2 receptor and TRPV channel by ATP: implications for ATP induced pain.	TRPV1 P2RY2	1.70e-05	2	144	2	16133936
Pubmed	IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.	RAG2 IGHM	1.70e-05	2	144	2	22366892
Pubmed	Tissue-specific distribution of mouse casein kinase I alpha mRNA.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	9522121
Pubmed	Intranasal prophylaxis with CpG oligodeoxynucleotide can protect against Yersinia pestis infection.	RAG2 IGHM	1.70e-05	2	144	2	23545300
Pubmed	CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	37723657
Pubmed	Casein Kinase 1α Regulates Testosterone Synthesis and Testis Development in Adult Mice.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	36929849
Pubmed	Generation of a mouse expressing a conditional knockout of the hepatocyte growth factor gene: demonstration of impaired liver regeneration.	RAG2 HGF	1.70e-05	2	144	2	15383179
Pubmed	Class III β-Tubulin Expression Is of Value in Selecting nab -Paclitaxel and Gemcitabine as First-Line Therapy in Unresectable Pancreatic Cancer.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	35695793
Pubmed	Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre-B cell receptor expression.	RAG2 IGHM	1.70e-05	2	144	2	9834086
Pubmed	Relationship of intercellular adhesion molecule-3 and hepatocyte growth factor with amyloidosis A in chronic renal-failure patients.	HGF ICAM3	1.70e-05	2	144	2	14704632
Pubmed	Capturing host-pathogen interactions by protein microarrays: identification of novel streptococcal proteins binding to human fibronectin, fibrinogen, and C4BP.	FN1 C4BPA	1.70e-05	2	144	2	19417080
Pubmed	Exploring the role of casein kinase 1α splice variants across cancer cell lines.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	38852281
Pubmed	Casein kinase 1 alpha regulates chromosome congression and separation during mouse oocyte meiotic maturation and early embryo development.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	23690993
Pubmed	Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonas aeruginosa.	P2RY1 P2RY2	1.70e-05	2	144	2	16024720
Pubmed	Analysis of stromal cell secretomes reveals a critical role for stromal cell-derived hepatocyte growth factor and fibronectin in angiogenesis.	HGF FN1	1.70e-05	2	144	2	23288153
Pubmed	Knockdown of Csnk1a1 results in preimplantation developmental arrest in mice.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	36542875
Pubmed	Fibronectin and Hepatocyte Growth Factor Produced by Lung Fibroblasts Augment Migration and Invasion of Malignant Pleural Mesothelioma Cells.	HGF FN1	1.70e-05	2	144	2	28476806
Pubmed	Cloning and tissue distribution of the human P2Y1 receptor.	P2RY1 P2RY2	1.70e-05	2	144	2	8630005
Pubmed	Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors.	P2RY1 P2RY2	1.70e-05	2	144	2	25937122
Pubmed	Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells.	RAG2 IGHM	1.70e-05	2	144	2	19833887
Pubmed	Germinal center alloantibody responses are mediated exclusively by indirect-pathway CD4 T follicular helper cells.	RAG2 IGHM	1.70e-05	2	144	2	22323543
Pubmed	Differences in susceptibility of inbred and outbred infant mice to enterotoxigenic Escherichia coli of bovine, porcine and human origin.	FN1 FBN2	1.70e-05	2	144	2	2179554
Pubmed	Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells.	P2RY1 P2RY2	1.70e-05	2	144	2	21653634
Pubmed	Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	25994086
Pubmed	Three-dimensional visualization of extracellular matrix networks during murine development.	FN1 FBN2	1.70e-05	2	144	2	29352963
Pubmed	Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity.	TRPV1 P2RY1	1.70e-05	2	144	2	12853424
Pubmed	Prostanoid-dependent bladder pain caused by proteinase-activated receptor-2 activation in mice: Involvement of TRPV1 and T-type Ca2+ channels.	TRPV1 CACNA1H	1.70e-05	2	144	2	29289470
Pubmed	Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors.	RAG2 IGHM	1.70e-05	2	144	2	18316379
Pubmed	Cloning of rat and mouse P2Y purinoceptors.	P2RY1 P2RY2	1.70e-05	2	144	2	7779087
Pubmed	ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan.	FN1 ADAMTS4	1.70e-05	2	144	2	15161923
Pubmed	Csnk1a1 inhibition modulates the inflammatory secretome and enhances response to radiotherapy in glioma.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	34216174
Pubmed	Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling.	CSNK1A1L CSNK1A1	1.70e-05	2	144	2	37108197
Pubmed	SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms.	RAG2 PSG4 PSG9	2.45e-05	14	144	3	17081782
Pubmed	CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.	RAG2 PSG4 PSG9	3.05e-05	15	144	3	25363763
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	DHX36 DNAJC13 DHX57 CNBP TRA2A HDAC1 KPNA2	4.23e-05	223	144	7	33731348
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	RNF31 TRIM31 TRIM65 TTC3 UBR3	4.87e-05	95	144	5	29643511
Pubmed	Casein kinase 1α inhibits p53 downstream of MDM2‑mediated autophagy and apoptosis in acute myeloid leukemia.	MDM2 CSNK1A1	5.09e-05	3	144	2	32901886
Pubmed	Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.	RAG2 SEMA4A	5.09e-05	3	144	2	37205755
Pubmed	Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut.	RAG2 IGHM	5.09e-05	3	144	2	22101768
Pubmed	Reduced Expression of P2Y2 Receptor and Acetylcholinesterase at Neuromuscular Junction of P2Y1 Receptor Knock-out Mice.	P2RY1 P2RY2	5.09e-05	3	144	2	26036470
Pubmed	Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma.	RAG2 IGHM	5.09e-05	3	144	2	18223654
Pubmed	Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.	FLRT3 FLRT1	5.09e-05	3	144	2	10644439
Pubmed	Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	24616378
Pubmed	Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer.	MDM2 HDAC1	5.09e-05	3	144	2	33985974
Pubmed	Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis.	RAG2 IGHM	5.09e-05	3	144	2	20817865
Pubmed	Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	25242043
Pubmed	Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.	HGF FN1	5.09e-05	3	144	2	19553700
Pubmed	Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	28655862
Pubmed	Characterization of new members of the pregnancy-specific beta 1-glycoprotein family.	PSG4 PSG9	5.09e-05	3	144	2	1922019
Pubmed	Combinatory inhibition of TRIM65 and MDM2 in lung cancer cells.	TRIM65 MDM2	5.09e-05	3	144	2	30454706
Pubmed	DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification.	METTL2A METTL2B	5.09e-05	3	144	2	32427860
Pubmed	Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding.	MDM2 CSNK1A1	5.09e-05	3	144	2	10734067
Pubmed	CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	28878021
Pubmed	Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	26811327
Pubmed	Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway.	P2RY1 P2RY2	5.09e-05	3	144	2	16741950
Pubmed	Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.	P2RY1 P2RY2	5.09e-05	3	144	2	19890001
Pubmed	Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.	CSNK1A1L CSNK1A1	5.09e-05	3	144	2	19805514
Pubmed	Bach2 deficiency leads autoreactive B cells to produce IgG autoantibodies and induce lupus through a T cell-dependent extrafollicular pathway.	RAG2 IGHM	5.09e-05	3	144	2	31819031
Pubmed	Quantitative proteomics revealed novel proteins associated with molecular subtypes of breast cancer.	FN1 C4BPA	5.09e-05	3	144	2	27498393
Pubmed	Knockdown of IRE1ɑ suppresses metastatic potential of colon cancer cells through inhibiting FN1-Src/FAK-GTPases signaling.	FN1 ERN1	5.09e-05	3	144	2	31326465
Pubmed	Innate, antigen-independent role for T cells in the activation of the immune system by Propionibacterium acnes.	RAG2 IGHM	5.09e-05	3	144	2	20690177
Pubmed	Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.	P2RY1 P2RY2	5.09e-05	3	144	2	12603858
Pubmed	Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation.	MDM2 HDAC1	5.09e-05	3	144	2	15640443
Pubmed	Paracrine purinergic signaling determines lung endothelial nitric oxide production.	P2RY1 P2RY2	5.09e-05	3	144	2	19304909
Pubmed	Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.	SEZ6L SEZ6	5.09e-05	3	144	2	27716410
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA6C FLRT3 FLRT1 SEMA4A	6.54e-05	52	144	4	26633812
Pubmed	Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.	DHX36 HGF DNAJC13 FN1 TRIM31 MDM2 CNBP TRA2A KPNA2	6.91e-05	421	144	9	34650049
Pubmed	Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.	FN1 BMP2K TGFBR3 FBN2	7.05e-05	53	144	4	33153107
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DHX36 DNAJC13 FN1 ANK3 SYT3 MARS1 DHX57 MDH2 PHKB CSNK1A1L CSNK1A1 IGHM ATP1A2 DNM1 CORO7 AP3D1 UNC13A	9.42e-05	1431	144	17	37142655
Pubmed	Serum amyloid p component does not circulate in complex with C4-binding protein, fibronectin or any other major protein ligand.	FN1 C4BPA	1.02e-04	4	144	2	12100475
Pubmed	FLRT3 Marks Direction-Selective Retinal Ganglion Cells That Project to the Medial Terminal Nucleus.	FLRT3 FLRT1	1.02e-04	4	144	2	34955746
Pubmed	Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response.	MDM2 CSNK1A1	1.02e-04	4	144	2	30598450
Pubmed	TRPV1 Nociceptor Activity Initiates USP5/T-type Channel-Mediated Plasticity.	TRPV1 CACNA1H	1.02e-04	4	144	2	27974205
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FN1 FBN2	1.02e-04	4	144	2	25034023
Pubmed	The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.	CSNK1A1L CSNK1A1	1.02e-04	4	144	2	32728212
Pubmed	FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma.	MDM2 HDAC1	1.02e-04	4	144	2	23677067
Pubmed	Co-localization of P2Y1 receptor and NTPDase1/CD39 within caveolae in human placenta.	P2RY1 P2RY2	1.02e-04	4	144	2	15590415
Pubmed	Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.	FN1 GPER1	1.02e-04	4	144	2	19342448
Pubmed	A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5.	RAG2 IGHM	1.02e-04	4	144	2	22949502
Pubmed	Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes.	P2RY1 P2RY2	1.02e-04	4	144	2	12787128
Pubmed	Homeostatic regulation of intestinal villous epithelia by B lymphocytes.	RAG2 IGHM	1.02e-04	4	144	2	11884426
Pubmed	Inhibition of epithelial to mesenchymal transition by E-cadherin up-regulation via repression of slug transcription and inhibition of E-cadherin degradation: dual role of scaffold/matrix attachment region-binding protein 1 (SMAR1) in breast cancer cells.	MDM2 HDAC1	1.02e-04	4	144	2	25086032
Pubmed	Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2.	RAG2 IGHM	1.02e-04	4	144	2	24218622
Pubmed	MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation.	MDM2 HDAC1	1.02e-04	4	144	2	12426395
Pubmed	Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria.	RAG2 IGHM	1.02e-04	4	144	2	25763578
Pubmed	Regulation of p53-MDMX interaction by casein kinase 1 alpha.	CSNK1A1L CSNK1A1	1.02e-04	4	144	2	16024788
Pubmed	A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis.	TRPV1 HDAC1	1.02e-04	4	144	2	29656858
Pubmed	Identification of a novel family of putative methyltransferases that interact with human and Drosophila presenilins.	METTL2A METTL2B	1.02e-04	4	144	2	11738826
Cytoband	3q25.2	DHX36 P2RY1 GPR149	8.45e-06	13	144	3	3q25.2
Cytoband	9q21.32	SPATA31D4 SPATA31D1 SPATA31D3	2.82e-05	19	144	3	9q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr5q23	C5orf63 FBN2 HSD17B4 PRDM6	5.23e-04	117	144	4	chr5q23
GeneFamily	ATP binding cassette subfamily A	ABCA12 ABCA7 ABCA6	6.61e-05	14	105	3	805
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CSMD3 C4BPA SEZ6L SEZ6	3.35e-04	57	105	4	1179
GeneFamily	Calcium voltage-gated channel subunits	CACNA1S CACNG7 CACNA1H	4.49e-04	26	105	3	253
GeneFamily	Purinergic receptors P2Y	P2RY1 P2RY2	1.46e-03	10	105	2	213
GeneFamily	CD molecules\|V-set domain containing\|Pregnancy specific glycoproteins	PSG4 PSG9	1.78e-03	11	105	2	1315
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	KIF24 THOC5 CACNG7 KCNC3 SLC15A2 SMPDL3A KCNJ14 PDZD2	2.97e-07	200	144	8	401d50fa394fa863fa7836344110ae5c7af3250a
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	ERN1 CPNE5 NXPE3 CFAP54 NLRP14 IGHM PAH	1.68e-06	175	144	7	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 TNFAIP8L3 ANK3 PPFIBP1 SLC45A3 KCNJ14 FLRT3	1.68e-06	175	144	7	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL1 FMO1 TNFAIP8L3 FBN2 P2RY1 FLRT3	3.17e-06	124	144	6	690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 CSMD3 TENM2 FBN2 SLCO1C1 ABCA6 ATP1A2	3.21e-06	193	144	7	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FMO1 FN1 CSMD3 TENM2 FBN2 SLCO1C1 UNC13A	3.67e-06	197	144	7	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERN1 CPNE5 NXPE3 CFAP54 SLC15A2 IGHM PAH	3.67e-06	197	144	7	749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPNE5 WDFY4 NXPE3 CFAP54 SLC15A2 IGHM PAH	3.67e-06	197	144	7	0f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERN1 CPNE5 NXPE3 CFAP54 SLC15A2 IGHM PAH	3.80e-06	198	144	7	567fcf882c8612356946240843525b786f3c8dbe
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FMO1 FN1 BBS9 TENM2 FBN2 SLCO1C1 ABCA6	3.80e-06	198	144	7	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERN1 CPNE5 WDFY4 NXPE3 CFAP54 SLC15A2 IGHM	3.92e-06	199	144	7	1bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERN1 CPNE5 WDFY4 NXPE3 CFAP54 SLC15A2 IGHM	3.92e-06	199	144	7	2f60682f1b82918a65e8851e99c9e3398845b62f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL1 FMO1 TNFAIP8L3 P2RY1 GPR149 FLRT3	4.17e-06	130	144	6	8bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H12A FN1 ABCA12 TRIM31 CSMD3 SLCO1C1	1.42e-05	161	144	6	b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H12A FN1 ABCA12 TRIM31 CSMD3 SLCO1C1	1.42e-05	161	144	6	f7a89c481f789f624102857be722c95fbeb47595
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLDN18 ANK3 C5orf63 ARFGEF3 C4BPA FLRT3	1.57e-05	164	144	6	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CLDN18 ANK3 C5orf63 ARFGEF3 C4BPA FLRT3	1.57e-05	164	144	6	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PDE3B ADAMTSL1 CSMD3 FBN2 ABCA6	2.20e-05	174	144	6	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 VASN TGFBR3 ABCA6 ATP1A2 PRDM6	2.75e-05	181	144	6	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 TNFAIP8L3 PPFIBP1 DUOX2 SLC45A3 FLRT3	2.75e-05	181	144	6	b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 VASN TGFBR3 ABCA6 ATP1A2 PRDM6	2.75e-05	181	144	6	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 TNFAIP8L3 PPFIBP1 DUOX2 SLC45A3 FLRT3	2.75e-05	181	144	6	cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 TNFAIP8L3 PPFIBP1 DUOX2 SLC45A3 FLRT3	2.75e-05	181	144	6	ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 VASN TGFBR3 ABCA6 ATP1A2 PRDM6	2.92e-05	183	144	6	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 CSMD3 ARFGEF3 FBN2 MYO15A UNC80	3.01e-05	184	144	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 CSMD3 ARFGEF3 FBN2 MYO15A UNC80	3.01e-05	184	144	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 CSMD3 ARFGEF3 FBN2 MYO15A UNC80	3.01e-05	184	144	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FMO1 FN1 LGALS3BP ABCA6 DNM1	3.10e-05	185	144	6	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FMO1 FN1 LGALS3BP ABCA6 DNM1	3.10e-05	185	144	6	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FMO1 FN1 LGALS3BP ABCA6 DNM1	3.10e-05	185	144	6	a94694e226856bc5b168464f52d76004145717a5
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK3 PPFIBP1 TENM2 FBN2 ATP1A2 PDZD2	3.10e-05	185	144	6	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF FN1 ADAMTS4 VASN ABCA6 PRDM6	3.20e-05	186	144	6	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TTC3 TENM2 ARFGEF3 DNM1 UNC13A UNC80	3.20e-05	186	144	6	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLDN18 TNFAIP8L3 ANK3 ARFGEF3 KCNC3 SLC15A2	3.40e-05	188	144	6	068b761a7b6778bc6d6c776b5f09094aac87477e
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLDN18 TNFAIP8L3 ANK3 ARFGEF3 KCNC3 SLC15A2	3.40e-05	188	144	6	c95134245dab9057eb1f9b54acb371470f9c8b86
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLDN18 TNFAIP8L3 ANK3 ARFGEF3 KCNC3 SLC15A2	3.40e-05	188	144	6	3ee321a74f04eb0982c7b4977426946b0ae6e5a9
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7\|World / Primary Cells by Cluster	FMO1 LGALS3BP SLCO1C1 LRP10 SLC15A2 ATP1A2	3.60e-05	190	144	6	8f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TTC3 TENM2 ARFGEF3 DNM1 UNC13A UNC80	3.60e-05	190	144	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN18 ANK3 ARFGEF3 GOT1L1 KCNC3 SLC15A2	3.60e-05	190	144	6	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte\|World / Primary Cells by Cluster	FMO1 LGALS3BP SLCO1C1 LRP10 SLC15A2 ATP1A2	3.60e-05	190	144	6	7dbfd543398c63cbe1e68b54bcb5e2291f521935
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHX36 BMP2K LCORL KMT5B CSNK1A1 HDAC1	3.71e-05	191	144	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CLDN18 ADAMTSL1 ANK3 FBN2 FLRT3 BCAM	3.71e-05	191	144	6	402c341b00f98e8215458766b3c219fff8dcb447
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHX36 BMP2K LCORL KMT5B CSNK1A1 HDAC1	3.71e-05	191	144	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TTC3 TENM2 ARFGEF3 DNM1 UNC13A UNC80	3.82e-05	192	144	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CLDN18 ADAMTSL1 ANK3 FBN2 FLRT3 BCAM	3.82e-05	192	144	6	567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE3B FN1 CSMD3 TENM2 ABCA6 PRDM6	4.05e-05	194	144	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ICAM3 CPNE5 NXPE3 CFAP54 SLC15A2 IGHM	4.16e-05	195	144	6	0b0615553b9a1b60d666d074ce4260919e2d5642
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF ADAMTSL1 VASN TGFBR3 ABCA6 DNM1	4.16e-05	195	144	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	severe-Lymphocytic-B_cells_1\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	BMP2K ZNF318 CPNE5 WDFY4 SLC15A2 IGHM	4.16e-05	195	144	6	73e39005a597e13aea571ae6ae5824d1c7448b71
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HGF PDE3B PPFIBP1 TENM2 ABCA6 PRDM6	4.16e-05	195	144	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	normal_Lung-Epithelial_cells\|normal_Lung / Location, Cell class and cell subclass	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.16e-05	195	144	6	7c90d887afde5c4d63352b5171be9987e2dfca58
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.16e-05	195	144	6	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPNE5 NXPE3 CFAP54 SLC15A2 IGHM PAH	4.28e-05	196	144	6	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	LAM-Epithelial\|LAM / Condition, Lineage and Cell class	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.41e-05	197	144	6	e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMO1 FN1 GPER1 VASN F2RL2 CACNA1H	4.41e-05	197	144	6	983502a99e6d59bb36225b0246a9990604de1a01
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3B FN1 TENM2 TGFBR3 ABCA6 PRDM6	4.41e-05	197	144	6	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 FN1 ADAMTS4 SLCO1C1 CACNA1H ATP1A2	4.53e-05	198	144	6	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	distal-Epithelial-Club-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN18 ARFGEF3 SLC15A2 C4BPA FLRT3 BCAM	4.53e-05	198	144	6	e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCell	Control_saline-Epithelial_alveolar-AT_1-AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	CLDN18 ACAD10 LGALS3BP FBN2 FLRT3 BCAM	4.53e-05	198	144	6	9f972f217d2c39d4c0f7d0d4227d0fffe8535b9d
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	CLDN18 LGALS3BP FBN2 SLC15A2 FLRT3 BCAM	4.53e-05	198	144	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	Mild/Remission-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZNF318 TENM2 CACNG7 KMT5B IGHM	4.62e-05	121	144	5	68940a552233d255b90ce5a081339c0d9d46ab02
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 PDZD2	4.66e-05	199	144	6	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B VASN PPFIBP1 QSOX1 HS6ST1 BCAM	4.66e-05	199	144	6	a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88
ToppCell	Biopsy_IPF-Epithelial-Transitional_AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	CLDN18 ABCA7 QSOX1 C4BPA FLRT3 BCAM	4.66e-05	199	144	6	83ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell	Biopsy_Other_PF-Epithelial-SCGB3A2+_SCGB1A1+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ARFGEF3 P2RY2 SLC15A2 C4BPA FLRT3 BCAM	4.66e-05	199	144	6	036244251d2dd39f8184b7095418c723c0524eff
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 PDZD2	4.66e-05	199	144	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPNE5 WDFY4 NXPE3 CFAP54 SLC15A2 IGHM	4.66e-05	199	144	6	58242d78517c05fa367a7c6edac57ef79107453c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.66e-05	199	144	6	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 TGFBR3 SLCO1C1 ABCA6 DNM1 PRDM6	4.66e-05	199	144	6	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.66e-05	199	144	6	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE3B BMP2K TENM2 SLCO1C1 SLC15A2 ATP1A2	4.79e-05	200	144	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE3B BMP2K TENM2 SLCO1C1 SLC15A2 ATP1A2	4.79e-05	200	144	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HGF ADAMTS4 VASN LGALS3BP CACNA1H PDZD2	4.79e-05	200	144	6	d70bad979299615fcba707ba21296020918705e6
ToppCell	proximal-Epithelial\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.79e-05	200	144	6	3790dd13c4ff471e716e5a2950f196e3c386dbb1
ToppCell	proximal-3-Epithelial\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.79e-05	200	144	6	08858bb20630849ffb2192631e23466c242a1078
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HGF ADAMTS4 VASN LGALS3BP CACNA1H PDZD2	4.79e-05	200	144	6	38c21ec379005f688df33aea65237a063c476c2e
ToppCell	Biopsy_Control_(H.)-Epithelial\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CLDN18 ANK3 ARFGEF3 C4BPA FLRT3 BCAM	4.79e-05	200	144	6	0afd93c4fdcc118bcfa77f3b59f6ff7d9293a7a4
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE3B BMP2K TENM2 SLCO1C1 SLC15A2 ATP1A2	4.79e-05	200	144	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Sigmoid-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	CFP ZNF318 CNBP GBP5 ABCA6 DNM1	4.79e-05	200	144	6	cdb3f242d0c80b4eb9044f59156443e77fb81a1d
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE3B BMP2K TENM2 SLCO1C1 SLC15A2 ATP1A2	4.79e-05	200	144	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PDE3B BMP2K TENM2 SLCO1C1 SLC15A2 ATP1A2	4.79e-05	200	144	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital\|World / Primary Cells by Cluster	ANK3 PPFIBP1 TTC3 TENM2 ARFGEF3 CSNK1A1	4.79e-05	200	144	6	6bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19\|World / Primary Cells by Cluster	ANK3 PPFIBP1 TTC3 TENM2 ARFGEF3 CSNK1A1	4.79e-05	200	144	6	c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTSL1 FMO1 TNFAIP8L3 FBN2 P2RY1	6.50e-05	130	144	5	60e28d452d0e2af768459ba8dbe998117c94a251
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HGF CFP SLC15A2 KCNJ14 HSD17B4	8.34e-05	137	144	5	12caa8ed7cc9e7a0f78c14ad5efe2fc28c3ce9be
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ADAMTS4 GPER1 P2RY1 WDR90 FLRT3	8.34e-05	137	144	5	b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C11orf42 NMUR2 SIAH3 PAH	1.08e-04	76	144	4	f653a09d6707d9b34db4ef486212aeba5610f47b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C11orf42 NMUR2 SIAH3 PAH	1.08e-04	76	144	4	47deea63d975366a42834c22cc163c4c7142d51d
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C11orf42 NMUR2 SIAH3 PAH	1.08e-04	76	144	4	079e1af894e670f63d718e16599f20d920643160
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	SIAH3 UNC13A UNC80 SEZ6L SEZ6	1.09e-04	145	144	5	1e52e3c615b49e7388cd58a04e74cafac9552447
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERN1 CFP WDFY4 SMPDL3A DNM1	1.12e-04	146	144	5	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17\|bone_marrow / Manually curated celltypes from each tissue	ZC3H12A ERN1 GBP5 UNC80 FOXD4	1.24e-04	149	144	5	264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCell	368C-Myeloid-Mast_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	BMP2K DUOX2 CFAP54 SLC45A3 HS6ST1	1.36e-04	152	144	5	faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCell	368C-Myeloid-Mast_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	BMP2K DUOX2 CFAP54 SLC45A3 HS6ST1	1.36e-04	152	144	5	519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG7 ASB5 C4BPA ATP1A2 SEZ6L	1.44e-04	154	144	5	30cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG7 ASB5 C4BPA ATP1A2 SEZ6L	1.44e-04	154	144	5	ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG7 ASB5 C4BPA ATP1A2 SEZ6L	1.44e-04	154	144	5	42bd8f88fd075a2d4edde394785decad88a2660a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNG7 ASB5 C4BPA ATP1A2 SEZ6L	1.44e-04	154	144	5	6425d9861148586466febd6eceae1b1f9b9a14c1
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERN1 CFP WDFY4 BAZ1A SEMA4A	1.53e-04	156	144	5	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B ANK3 PSG4 ABCA12 F2RL2	1.58e-04	157	144	5	2c5295043611bac7dfa4aef2146681bce4a33a8f
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TRPV1 RNF31 ANK3 ZNF862 ZNF318 MDM2 MAP3K6 SEMA4A AP3D1	3.45e-06	191	143	9	4969_DN
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A	HGF FN1 ERN1 ZNF862 MDM2 P2RY1 TRA2A CACNA1H ATP1A2	4.45e-06	197	143	9	2241_UP
Disease	phenylketonuria (implicated_via_orthology)	DUOX2 PAH	1.28e-04	4	137	2	DOID:9281 (implicated_via_orthology)
Disease	pregnancy-specific beta-1-glycoprotein 9 measurement	PSG4 PSG9	1.28e-04	4	137	2	EFO_0801909
Disease	Hypokalemic periodic paralysis	CACNA1S ATP1A2	1.28e-04	4	137	2	C0238358
Disease	pregnancy-specific beta-1-glycoprotein 4 measurement	PSG4 PSG9	3.17e-04	6	137	2	EFO_0801907
Disease	cerebral cortex growth measurement	ADAMTSL1 PPFIBP1	3.17e-04	6	137	2	EFO_0009328
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1A1L CSNK1A1	4.43e-04	7	137	2	DOID:0060807 (implicated_via_orthology)
Disease	biliary tract benign neoplasm (is_marker_for)	HGF MDM2	4.43e-04	7	137	2	DOID:0050625 (is_marker_for)
Disease	free cholesterol in medium LDL measurement	TDRD15 ABCA6 BCAM	8.53e-04	40	137	3	EFO_0022268
Disease	transverse temporal cortex volume measurement	HGF P2RY1	9.40e-04	10	137	2	EFO_0010336
Disease	concentration of large LDL particles measurement	TDRD15 ABCA6 BCAM	1.13e-03	44	137	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	TDRD15 ABCA6 BCAM	1.13e-03	44	137	3	EFO_0022225
Disease	Malignant neoplasm of breast	FN1 SYT3 GPER1 CFP ZNF318 MDM2 TTC3 MAP3K6 THOC5 PHKB NLRP14 UTP20 PLEKHA8	1.52e-03	1074	137	13	C0006142
Disease	phospholipids in medium LDL measurement	TDRD15 ABCA6 BCAM	1.54e-03	49	137	3	EFO_0022183
Disease	intercellular adhesion molecule 5 measurement	ICAM3 ABCA6	1.61e-03	13	137	2	EFO_0008164
Disease	free cholesterol in LDL measurement	TDRD15 ABCA6 BCAM	1.64e-03	50	137	3	EFO_0022266
Disease	free cholesterol in large LDL measurement	TDRD15 ABCA6 BCAM	1.73e-03	51	137	3	EFO_0022176
Disease	cholesterol to total lipids in small VLDL percentage	TDRD15 ABCA6 BCAM	1.73e-03	51	137	3	EFO_0022242
Disease	phospholipids in IDL measurement	TDRD15 ABCA6 BCAM	1.83e-03	52	137	3	EFO_0022164
Disease	total lipids in LDL measurement	TDRD15 ABCA6 BCAM	1.83e-03	52	137	3	EFO_0022308
Disease	phospholipids in large LDL measurement	TDRD15 ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022174
Disease	triglycerides to total lipids in very large VLDL percentage	TDRD15 ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022340
Disease	free cholesterol in small LDL measurement	TDRD15 ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022271
Disease	cholesteryl esters to total lipids in very large VLDL percentage	TDRD15 ABCA6 BCAM	1.94e-03	53	137	3	EFO_0022258
Disease	cholesterol to total lipids in very large VLDL percentage	TDRD15 ABCA6 BCAM	2.04e-03	54	137	3	EFO_0022244
Disease	Drug habituation	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0013170
Disease	Drug abuse	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0013146
Disease	Prescription Drug Abuse	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C4316881
Disease	Substance-Related Disorders	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0236969
Disease	Drug Use Disorders	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0013222
Disease	Drug Dependence	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C1510472
Disease	Substance Dependence	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0038580
Disease	Substance Use Disorders	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	C5orf63 CSMD3 TENM2 QSOX1	2.06e-03	115	137	4	C0029231
Disease	pulse pressure measurement	TDRD15 FN1 LCORL VASN TRIM65 ZNF318 ACAD10 CPNE5 QSOX1 TGFBR3 FBN2 UBR3 CORO7 AP3D1 PRDM6	2.09e-03	1392	137	15	EFO_0005763
Disease	Substance abuse problem	C5orf63 CSMD3 TENM2 QSOX1	2.13e-03	116	137	4	C0740858
Disease	impotence (implicated_via_orthology)	P2RY1 P2RY2	2.16e-03	15	137	2	DOID:1875 (implicated_via_orthology)
Disease	free cholesterol to total lipids in large HDL percentage	TDRD15 ABCA6 BCAM	2.27e-03	56	137	3	EFO_0022279
Disease	total lipids in large LDL	TDRD15 ABCA6 BCAM	2.39e-03	57	137	3	EFO_0022163
Disease	cholesterol in large LDL measurement	TDRD15 ABCA6 BCAM	2.39e-03	57	137	3	EFO_0021901
Disease	triglycerides to total lipids in small VLDL percentage	TDRD15 ABCA6 BCAM	2.51e-03	58	137	3	EFO_0022338
Disease	cholesterol in IDL measurement	TDRD15 ABCA6 BCAM	2.51e-03	58	137	3	EFO_0021899
Disease	phospholipids in LDL measurement	TDRD15 ABCA6 BCAM	2.51e-03	58	137	3	EFO_0022294
Disease	phospholipids in small LDL measurement	TDRD15 ABCA6 BCAM	2.63e-03	59	137	3	EFO_0022297
Disease	free cholesterol to total lipids in very large VLDL percentage	TDRD15 ABCA6 BCAM	2.63e-03	59	137	3	EFO_0022289
Disease	total lipids in IDL	TDRD15 ABCA6 BCAM	2.76e-03	60	137	3	EFO_0022161
Disease	free cholesterol in IDL measurement	TDRD15 ABCA6 BCAM	2.89e-03	61	137	3	EFO_0022181
Disease	cD177 antigen measurement	PSG4 PSG9	3.12e-03	18	137	2	EFO_0021866
Disease	triglycerides to total lipids in medium VLDL percentage	TDRD15 ABCA6 BCAM	3.17e-03	63	137	3	EFO_0022335
Disease	Headache	HGF TGFBR3 GPR149	3.32e-03	64	137	3	HP_0002315
Disease	obesity (implicated_via_orthology)	ADAMTS4 NMUR2 SLC15A2 HSD17B4 CORO7	3.37e-03	215	137	5	DOID:9970 (implicated_via_orthology)
Disease	coronary artery disease	TDRD15 DNAJC13 FN1 LCORL DUOX2 TRIM65 ACAD10 FBN2 GPR149 CORO7 PRDM6 UNC13A SEZ6L	3.79e-03	1194	137	13	EFO_0001645
Disease	sporadic amyotrophic lateral sclerosis	ADAMTSL1 ANK3 ABCC12 UNC13A	4.19e-03	140	137	4	EFO_0001357
Disease	family history of Alzheimer’s disease	ADAMTS4 ABCA7 BCAM	4.44e-03	71	137	3	EFO_0009268

Protein segments in the cluster

Peptide	Gene	Start	Entry
SFQFTLSADAGPECY	UNC13A	1601	Q9UPW8
LDAPKTISSDCGAFY	C5orf63	106	A6NC05
GFSVTYSCDPRFSLL	C4BPA	196	P04003
DKTFPISQDGFLCTS	CFAP54	1661	Q96N23
ISQDGFLCTSVLPFY	CFAP54	1666	Q96N23
ISFECFPGYTLIGNS	CSMD3	2246	Q7Z407
GFFPFLQTLLCDTDS	ABCA12	66	Q86UK0
FFDIPCQGLYTSDLE	GOT1L1	211	Q8NHS2
FIYCNDRFLTSIPTG	FLRT3	41	Q9NZU0
CLGFTVFYEQLPSSL	ABCA6	341	Q8N139
SCARSDLYFVPLEGS	ATN1	776	P54259
LSTLGDPLADVAYSC	ACAD10	486	Q6JQN1
FFTLPFGESQVAICD	BMP2K	261	Q9NSY1
EYSLDSCDLGLLSSP	ANXA2R	46	Q3ZCQ2
YCPQSDAIFELLTGR	ABCA7	1871	Q8IZY2
SEGPLCELLFFFLTA	BAZ1A	466	Q9NRL2
TPCYSDAFAKLLESG	AP3D1	1051	O14617
ASLGGCSQDFLLFSP	NFE2L1	366	Q14494
DFEFGCATSYILPEL	RAG2	186	P55895
VTDFPSCYLLFRNGS	QSOX1	231	O00391
TTFTLLGFSDYPELQ	OR5D18	11	Q8NGL1
QLSFVDFCYSSIIAP	OR5D18	66	Q8NGL1
GLASLNSCVDPILYF	P2RY1	311	P47900
NSCVDPILYFLAGDT	P2RY1	316	P47900
PCNVTLEDFYGVFSS	LRP10	191	Q7Z4F1
NYGFSCSSDELPVLG	LGALS3BP	491	Q08380
LNSTEEYLAFLCGPR	NMUR2	26	Q9GZQ4
EVLGAPFTCFDASQY	MBTPS1	676	Q14703
PVFDGLFEFCQLSTG	HDAC1	101	Q13547
LEYSNGIFDCQSPTS	PPFIBP1	26	Q86W92
GLDCYLDSLFDPVLS	MYO15A	2386	Q9UKN7
LSDSQFLFGSQFCPE	IHO1	36	Q8IYA8
FLFGSQFCPENSETL	IHO1	41	Q8IYA8
FIFSELLANLYSCGD	DNM1	696	Q05193
QETECTYFSTPLLLG	MDH2	281	P40926
FGDVLCDSPYQLILS	SMPDL3A	76	Q92484
CDSPYQLILSAFDFI	SMPDL3A	81	Q92484
TDSGFEILPCNRYSS	KMT5B	191	Q4FZB7
ACGETLNIDFSLPFT	KIAA1109	556	Q2LD37
DSYFLHGDLSPLCLN	LCORL	476	Q8N3X6
QCAPLTVLDFFEGSS	DUOX2	581	Q9NRD8
DGSFLELPETFCSAS	ADAMTSL1	761	Q8N6G6
LPESPFFLECNSFTS	CORO7	761	P57737
ARLLEATPTDSCGYF	MAP3K6	221	O95382
TLFPNSYLLVGVCSD	PCYT1B	101	Q9Y5K3
LCSEDYSAGPSAVLF	PDZD2	2496	O15018
DESYGCLSSNIPALE	PDE3B	796	Q13370
TEFTCGLDFSLQSPT	PEX7	286	O00628
CADEFPGSSATYRIL	METTL2B	171	Q6P1Q9
LFSPNYLSAILGDCD	KIF24	171	Q5T7B8
SSDYCSALLKDIFGP	GBP5	401	Q96PP8
DDFVSTIDLPNYGCT	HGF	591	P14210
DLLGPSLEDLFNFCS	CSNK1A1L	91	Q8N752
EDSGIPTEAFLASCY	PLEKHA8	326	Q96JA3
GSDPVLCFTQYEESS	CFP	26	P27918
FFLGNLSTLDICYTP	OR13J1	61	Q8NGT2
TLSGICAFISDRFPY	FOXD4	126	Q12950
SANSCLDPVLYFLAG	P2RY2	296	P41231
DLSLVGCYNLSFIPE	HS6ST1	256	O60243
GLLSSFGELQYCLSE	PAH	346	P00439
DFACSFSGSIPLQEY	BBS9	631	Q3SYG4
GYFLCLSSLGSLENP	MVB12A	51	Q96EY5
CTLDGLFPASEAQVY	ICAM3	241	P32942
FPGSLTAFCYENELA	KCNJ14	381	Q9UNX9
CADEFPGSSATYRIL	METTL2A	171	Q96IZ6
DICNEFPVVFSGLFS	PASD1	136	Q8IV76
LGSLNSCLDPFLYFL	F2RL2	346	O00254
DSYTSFFGIPLQCIA	PRDM6	366	Q9NQX0
EVPGYFQFLCTTSAL	GPR149	96	Q86SP6
SFLGRTDCSPIQFES	KPNA2	126	P52292
LCLLDTAFFVNSSYP	PLA2G4E	696	Q3MJ16
LEETALAAFLSYCPG	ATP1A2	956	P50993
PCSARFITDFLDNGY	ADAMTS4	406	O75173
VGCLAQDFLPDSITF	IGHM	26	P01871
LPSAERYIDFCESGL	CRHBP	131	P24387
TLGSLPDDFVCYFTS	ERN1	921	O75460
EIDTFLASSGGLYCL	CACNA1S	1201	Q13698
SCTFDNLSPGLEYNV	FN1	1231	P02751
SPYCLLFFGGDISIQ	DHX36	906	Q9H2U1
ELFSDYFNSCPVITI	DHX57	706	Q6P158
LKFIYEGSSDFSCLP	HSD17B4	361	P51659
CITYTPTFDLNGSAV	ARFGEF3	121	Q5TH69
CTGFLTNPYLPLDSF	FMO1	146	Q01740
LSSNIPDGFCEQSAF	ANK3	2971	Q12955
QGSPSCAELLLEYGA	ASB5	146	Q8WWX0
LSDCSDYSGQFLQPE	CACNG7	221	P62955
TFALCAPYSETTEGQ	DNAJC13	536	O75165
LLAFGTSCSVVLYDP	ELP2	31	Q6IA86
FIYCNDRGLTSIPAD	FLRT1	36	Q9NZU1
PTGFSYNDLLLVCED	FBN2	1836	P35556
SSYDTSALCNGFPLE	FBXO30	276	Q8TB52
FDSNGTYVCEASLPT	BCAM	416	P50895
TLASFSEPGSCYEEL	CACNA1H	446	O95180
SGENLYLSCFAESNP	PSG4	346	Q00888
SLCYFTPILGAAIAD	SLC15A2	91	Q16348
QSSGFTECRPYFTIL	CLDN18	56	P56856
TFSIPVRALCNGDYD	CPNE5	231	Q9HCH3
NTDAALLPCISYPAF	PHKB	291	Q93100
DLGELNFSLCYLPTA	SYT3	431	Q9BQG1
PSFLSYIVNCFLIDD	UTP20	421	O75691
TFPVCLLASYDEISG	TRIM31	371	Q9BZY9
QYTCNPGFVLEGSSL	SEZ6L	831	Q9BYH1
VLEDFNLCLFYLPSS	SMG5	316	Q9UPR3
LTYRCFVSFPLNTGD	TMEM126A	81	Q9H061
FVSFPLNTGDLDCET	TMEM126A	86	Q9H061
SPQSLCLVLVDYGFS	TDRD15	1806	B5MCY1
GNLPLCNFTDLYTGE	NXPE3	231	Q969Y0
DLSCFTESNPPAEYF	PSG9	351	Q00887
DLLGPSLEDLFNFCS	CSNK1A1	91	P48729
NSCLNPLIYSFLGET	GPER1	316	Q99527
YCSNDLLGDLFGVPS	MDM2	76	Q00987
AFSPACTFIELQDSY	SEMA4A	146	Q9H3S1
GTPTQADCFTYRLEL	SIAH3	191	Q8IW03
EEFSPNSYLLRACSG	TENM2	216	Q9NT68
CFLNSYTETGLSPDS	SPATA31D4	6	Q6ZUB0
FGTYDSLLCFLSPVG	SLC25A53	96	Q5H9E4
SDSYSLFEAALFCPL	ABCC12	226	Q96J65
ISGNYLPSCFGTSLE	OCRL	671	Q01968
SALAPYLGTQEECLF	SLC45A3	186	Q96JT2
CFLYKPLSESSDGLE	SLCO4A1	686	Q96BD0
IDALSFYLPLESGNC	HTR3D	246	Q70Z44
RGFQFVSSSLPDICY	CNBP	41	P62633
AVPFLSDAACYDLLG	C11orf42	36	Q8N5U0
AGACPEEIFSALQYS	RNF31	501	Q96EP0
CFLNSYTETGLSPDS	SPATA31D3	6	P0C874
FLSTLYSLDGDCRPN	TNFAIP8L3	261	Q5GJ75
NLYTSDLCFEPAISG	WDR90	176	Q96KV7
DSLPYVSQDCLDSGI	ZC3H12A	426	Q5D1E8
TFSCQALPSEGFSLE	TSNARE1	231	Q96NA8
PLKSLDFCYGNEDLT	UNC80	2326	Q8N2C7
FYFGELPLSLAACTN	TRPV1	246	Q8NER1
APGFLEDASRTLCYL	KBTBD13	166	C9JR72
CFLNSYTETGLSPDS	SPATA31D1	6	Q6ZQQ2
DPNTCLGVFGLSLYT	TRA2A	116	Q13595
SEFESLLDCSPYLAG	SOGA1	931	O94964
YLLFLSLFALGCENS	SLCO1C1	436	Q9NYB5
FYICENFTLSPTGDV	WDFY4	2416	Q6ZS81
LSVVFPCYNSTELAG	TTC3	1851	P53804
NCSVPGDSTFYFDVL	SEMA6C	286	Q9H3T2
LSSPTDVGLDCFFYI	SEZ6	261	Q53EL9
EQLISYGSCQFPTLG	TOP3A	236	Q13472
ELDYADFGCPATTTT	VASN	341	Q6EMK4
FECSLPTGYSEEALL	ZNF862	976	O60290
LASCLGLLPTFYQTE	UBR3	1681	Q6ZT12
KLVFSSYPGTIFSCD	PLBD2	296	Q8NHP8
AGDLLSPDSVLSCLY	THOC5	391	Q13769
DLASGCLTFYSLEPQ	TRIM65	456	Q6PJ69
GSEFLVPISGFYCQL	ZNF318	1126	Q5VUA4
SLVFPCSALGAEDNY	MARS1	561	P56192
ELGFAIQTCFISPYS	TGFBR3	631	Q03167
ACFLLTDYAPSPDGS	KCNC3	706	Q14003
FITFPDGCQDISTSL	NLRP14	711	Q86W24