Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP2 ENTPD6 ENTPD3 ENTPD5

4.36e-06121984GO:0004382
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

GBP2 ENTPD6 ENTPD3 ENTPD5

4.01e-05201984GO:0017110
GeneOntologyMolecularFunctionUDP phosphatase activity

ENTPD6 ENTPD3 ENTPD5

7.72e-0591983GO:0045134
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO9 TSPOAP1 SLCO3A1 HCN2 CHRNA7 SLC38A10 SLC24A4 UCP1 KCNJ12 UCP3 SCNN1B SLC49A3 CHRFAM7A SLC22A20P SLC23A2 SLC52A1 GRIN2B FLVCR2 SLC2A5 SLC4A2 ABCA6 SLC22A2 SLC6A20 SLC28A1 SLC16A10

2.78e-04118019825GO:0022857
GeneOntologyMolecularFunctionchloride channel regulator activity

ANO9 CHRNA7 CHRFAM7A

4.00e-04151983GO:0017081
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

AVPR2 OR13C8 OR10J3 MC5R GPR37L1 PTGER3 NPFFR1 OR1L3 CHRNA7 OR4M2B IL1R2 TAAR9 CHRFAM7A PLXNB1 PLXNB3 GPR17 OR4K2 OR4M1 GRIN2B GRM5 GRM6 OR4L1 OR4M2 TNFRSF1B IL2RA OR1L4 EPHB1

4.03e-04135319827GO:0004888
GeneOntologyMolecularFunctiontransporter activity

ANO9 TSPOAP1 SLCO3A1 HCN2 CHRNA7 SLC38A10 SLC24A4 UCP1 KCNJ12 UCP3 SCNN1B SLC49A3 CHRFAM7A SLC22A20P SLC23A2 SLC52A1 ATG2B GRIN2B FLVCR2 SLC2A5 SLC4A2 ABCA6 SLC22A2 SLC6A20 SLC28A1 SLC16A10

4.43e-04128919826GO:0005215
GeneOntologyMolecularFunctionCDP phosphatase activity

ENTPD6 ENTPD5

5.79e-0441982GO:0036384
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRIN2B GRM5

5.79e-0441982GO:0099583
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO3A1 SLC38A10 SLC22A20P SLC23A2 SLC52A1 GRIN2B SLC4A2 SLC22A2 SLC6A20 SLC16A10

7.14e-0429319810GO:0008514
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NUGGC SPG7 GBP7 GBP2 HELB DHX29 DNAH8 DNAH3 RASA1 NLRP1 MSH2 GTPBP1 ABCA6 ENTPD6 ENTPD3 ENTPD5 HLTF MACF1 DHX32

7.19e-0484019819GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NUGGC SPG7 GBP7 GBP2 HELB DHX29 DNAH8 DNAH3 RASA1 NLRP1 MSH2 GTPBP1 ABCA6 ENTPD6 ENTPD3 ENTPD5 HLTF MACF1 DHX32

7.19e-0484019819GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

NUGGC SPG7 GBP7 GBP2 HELB DHX29 DNAH8 DNAH3 RASA1 NLRP1 MSH2 GTPBP1 ABCA6 ENTPD6 ENTPD3 ENTPD5 MACF1 DHX32

7.34e-0477519818GO:0017111
GeneOntologyMolecularFunctionIDP phosphatase activity

ENTPD6 ENTPD5

9.59e-0451982GO:1990003
GeneOntologyMolecularFunctionstructural constituent of egg coat

ZP2 ZP4

9.59e-0451982GO:0035804
GeneOntologyMolecularFunctionoxidative phosphorylation uncoupler activity

UCP1 UCP3

9.59e-0451982GO:0017077
GeneOntologyMolecularFunctionDNA/RNA hybrid binding

POLR1A POLR3B

9.59e-0451982GO:0071667
GeneOntologyCellularComponentspine apparatus membrane

CHRNA7 CHRFAM7A

2.63e-0431972GO:0098897
GeneOntologyCellularComponentt-UTP complex

HEATR1 UTP4

2.63e-0431972GO:0034455
GeneOntologyCellularComponentapical plasma membrane

SLCO3A1 CHRNA7 SLC24A4 PKHD1 SCNN1B CHRFAM7A SLC23A2 VCAM1 SLC2A5 SLC4A2 SLC22A2 SLC6A20 SLC28A1

7.53e-0448719713GO:0016324
GeneOntologyCellularComponentaxolemma

CHRNA7 CHRFAM7A CNTNAP2

9.67e-04211973GO:0030673
GeneOntologyCellularComponentcholinergic synapse

CHRNA7 CHRFAM7A SLC22A2

1.11e-03221973GO:0098981
GeneOntologyCellularComponenthost intracellular region

GBP7 GBP2

1.29e-0361972GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP7 GBP2

1.29e-0361972GO:0030430
GeneOntologyCellularComponenthost cell part

GBP7 GBP2

1.29e-0361972GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP7 GBP2

1.29e-0361972GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP7 GBP2

1.29e-0361972GO:0033655
GeneOntologyCellularComponentegg coat

ZP2 ZP4

1.29e-0361972GO:0035805
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP7 GBP2

1.29e-0361972GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP7 GBP2

1.29e-0361972GO:0020005
DomainGDA1_CD39_NTPase

ENTPD6 ENTPD3 ENTPD5

6.04e-0581953IPR000407
DomainGDA1_CD39

ENTPD6 ENTPD3 ENTPD5

6.04e-0581953PF01150
DomainGDA1_CD39_NTPASE

ENTPD6 ENTPD3 ENTPD5

6.04e-0581953PS01238
DomainMed13_N

MED13 MED13L

1.08e-0421952PF11597
DomainMediator_Med13_N_met/fun

MED13 MED13L

1.08e-0421952IPR021643
DomainMed13_C

MED13 MED13L

1.08e-0421952PF06333
DomainVCAM-1

VCAM1 CD22

1.08e-0421952IPR003989
DomainMediator_Med13

MED13 MED13L

1.08e-0421952IPR009401
Domain-

MSH2 MSH4

3.23e-04319523.30.420.110
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYCBP2 CUL9 ZNF318 TRRAP DDB1 URB1 AP1B1 ZNF638 PTCD3 TNPO1 POLR1A MSH2 NUP214 HEATR1 MTOR UTP4 PDCD11 MACF1

5.22e-086532001822586326
Pubmed

Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes.

ENTPD6 ENTPD3 ENTPD5

7.46e-07420039271669
Pubmed

The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.

ENTPD6 ENTPD3 ENTPD5

7.46e-07420039676430
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

CUL9 AARS2 MED13 PLXNB3 TOPBP1 ZMIZ1 CNTNAP2 MACF1

9.27e-07130200812421765
Pubmed

FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.

MYCBP2 MED13 MED13L MTOR

1.38e-0615200431285543
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

SPG7 MYCBP2 PSMA5 PSMB3 NCAPH2 AARS2 STRN4 TNPO1 ATG2B NUP214 HEATR1 WDR59 MTOR HLTF DHX32

2.65e-066062001536538041
Pubmed

The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.

TPO SLCO3A1 TG SLC16A10

4.78e-0620200424265449
Pubmed

Regulation of NMDA receptor trafficking by amyloid-beta.

CHRNA7 CHRFAM7A GRIN2B

6.45e-067200316025111
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR37L1 NPFFR1 TAAR9 GPR17 GRM5 GRM6

6.58e-0679200612679517
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MYCBP2 TRRAP DDB1 URB1 DHX29 POLR1A TOPBP1 MSH2 HEATR1 ZFC3H1 GTPBP1 POLR3B ARID2 PDCD11 MACF1 HDAC1

9.29e-067592001635915203
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TBC1D9B ADAM15 FANCA URB1 TM9SF2 AARS2 AP1B1 LPCAT2 FDFT1 CORO7 TNPO1 POLR1A ADRM1 MSH2 NUP214 HEATR1 SLC4A2 MTOR

9.65e-069422001831073040
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

ACACB MYCBP2 HMGCR ZNF318 DDB1 ATG2B NUP214 ISOC2 QSER1

1.22e-05242200934011540
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DIS3L2 MYCBP2 PSMA5 PSMB3 TRRAP DDB1 URB1 A2ML1 ZNF638 CORO7 DHX29 PTCD3 POLR1A MSH2 NUP214 HEATR1 WDR59 POLR3B UTP4 HLTF PDCD11 MACF1

1.23e-0513532002229467282
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

ACACB MYCBP2 PSMA5 ZNF318 NCAPH2 DDB1 ZNF638 TNPO1 ADRM1 NUP214 HEATR1 STIL UTP4 HDAC1

1.72e-056242001433729478
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TBC1D9B SPG7 GTPBP6 MYCBP2 OBSCN CUL9 TRRAP FANCA DACT1 URB1 SLC38A10 STRN4 MED13 NUP214 MED13L WDR59 MTOR TMEM268 PDCD11

2.34e-0511052001935748872
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYCBP2 URB1 PKHD1 ZNF638 POLR1A HEATR1 ZFC3H1 PDCD11

2.40e-05202200824639526
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

DDB1 AARS2 AP1B1 FDFT1 ALDH16A1 STRN4 PTCD3 TNPO1 CNOT10 POLR3B UTP4 HLTF HDAC1

2.44e-055602001335241646
Pubmed

Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair.

CHRNA7 CHRFAM7A TNFRSF1B

2.99e-0511200332908007
Pubmed

Involvement of heparan sulfate 6-O-sulfation in the regulation of energy metabolism and the alteration of thyroid hormone levels in male mice.

UCP1 UCP3 TG

2.99e-0511200323690091
Pubmed

Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.

CHRNA7 CHRFAM7A

3.29e-052200238070724
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRNA7 CHRFAM7A

3.29e-052200234453977
Pubmed

Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

CHRNA7 CHRFAM7A

3.29e-052200226999808
Pubmed

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

CHRNA7 CHRFAM7A

3.29e-052200227129924
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

3.29e-052200223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRNA7 CHRFAM7A

3.29e-052200228258105
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRNA7 CHRFAM7A

3.29e-052200219344760
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

3.29e-052200229114104
Pubmed

Endothelin 1, NF-κB, and ADAM-15 expression in diabetic foot wounds.

ADAM15 EDN1

3.29e-052200230685994
Pubmed

Genome Maintenance by DNA Helicase B.

HELB TOPBP1

3.29e-052200232455610
Pubmed

Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.

CHRNA7 CHRFAM7A

3.29e-052200233995108
Pubmed

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.

CHRNA7 CHRFAM7A

3.29e-052200232552811
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRNA7 CHRFAM7A

3.29e-052200224836856
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRNA7 CHRFAM7A

3.29e-052200215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRNA7 CHRFAM7A

3.29e-052200235678315
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRNA7 CHRFAM7A

3.29e-052200212628457
Pubmed

Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.

CHRNA7 CHRFAM7A

3.29e-052200225157794
Pubmed

Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

3.29e-052200231202708
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRNA7 CHRFAM7A

3.29e-052200222246862
Pubmed

Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.

CHRNA7 CHRFAM7A

3.29e-052200227471776
Pubmed

Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.

CHRNA7 CHRFAM7A

3.29e-052200222688057
Pubmed

Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.

CHRNA7 CHRFAM7A

3.29e-052200232028688
Pubmed

Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.

CHRNA7 CHRFAM7A

3.29e-052200230429582
Pubmed

A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.

CHRNA7 CHRFAM7A

3.29e-052200221501254
Pubmed

Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.

CHRNA7 CHRFAM7A

3.29e-052200221368056
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRNA7 CHRFAM7A

3.29e-05220021400473
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRNA7 CHRFAM7A

3.29e-052200226937017
Pubmed

Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons.

PLXNB1 RASA1

3.29e-052200220610402
Pubmed

Uncoupling Proteins and the Molecular Mechanisms of Thyroid Thermogenesis.

UCP1 UCP3

3.29e-052200226636187
Pubmed

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.

CHRNA7 CHRFAM7A

3.29e-052200236603528
Pubmed

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.

CHRNA7 CHRFAM7A

3.29e-052200226650489
Pubmed

Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.

CHRNA7 CHRFAM7A

3.29e-052200222848433
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRNA7 CHRFAM7A

3.29e-052200216650968
Pubmed

Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.

CHRNA7 CHRFAM7A

3.29e-052200235413868
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRNA7 CHRFAM7A

3.29e-052200224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRNA7 CHRFAM7A

3.29e-052200229261717
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRNA7 CHRFAM7A

3.29e-052200218199426
Pubmed

Elevated Thyroid Autoantibodies Aggravate Stroke Severity in Euthyroidism with Acute Ischemic Stroke.

TPO TG

3.29e-052200235256895
Pubmed

Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.

CHRNA7 CHRFAM7A

3.29e-052200222490926
Pubmed

Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.

CHRNA7 CHRFAM7A

3.29e-052200223270857
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRNA7 CHRFAM7A

3.29e-052200218077004
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRNA7 CHRFAM7A

3.29e-052200219462340
Pubmed

Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.

CHRNA7 CHRFAM7A

3.29e-052200216923147
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

3.29e-052200211790782
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRNA7 CHRFAM7A

3.29e-052200237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRNA7 CHRFAM7A

3.29e-052200219631623
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRNA7 CHRFAM7A

3.29e-052200215770102
Pubmed

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.

CHRNA7 CHRFAM7A

3.29e-052200224326163
Pubmed

Human milk anti-inflammatory component contents during acute mastitis.

IL1R2 TNFRSF1B

3.29e-052200211520075
Pubmed

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.

CHRNA7 CHRFAM7A

3.29e-052200223811428
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRNA7 CHRFAM7A

3.29e-052200220720594
Pubmed

Binding of transcription factor activating protein 2 γ on the 5'-proximal promoter region of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B.

SLC52A1 TFAP2C

3.29e-052200222702469
Pubmed

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.

CHRNA7 CHRFAM7A

3.29e-052200217019565
Pubmed

Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.

CHRNA7 CHRFAM7A

3.29e-052200219100751
Pubmed

Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.

CHRNA7 CHRFAM7A

3.29e-052200235883638
Pubmed

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.

CHRNA7 CHRFAM7A

3.29e-052200219368846
Pubmed

Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.

CHRNA7 CHRFAM7A

3.29e-052200215009674
Pubmed

Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.

CHRNA7 CHRFAM7A

3.29e-052200238253622
Pubmed

The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.

CHRNA7 CHRFAM7A

3.29e-052200234514543
Pubmed

α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.

CHRNA7 CHRFAM7A

3.29e-052200222183893
Pubmed

Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.

CHRNA7 CHRFAM7A

3.29e-05220029364063
Pubmed

Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

3.29e-052200212606407
Pubmed

Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.

CHRNA7 CHRFAM7A

3.29e-052200222300029
Pubmed

GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.

CHRNA7 CHRFAM7A

3.29e-052200232018068
Pubmed

Human lymphatic filariasis: genetic polymorphism of endothelin-1 and tumor necrosis factor receptor II correlates with development of chronic disease.

EDN1 TNFRSF1B

3.29e-052200221673044
Pubmed

CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.

CHRNA7 CHRFAM7A

3.29e-052200226206074
Pubmed

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.

CHRNA7 CHRFAM7A

3.29e-052200224349346
Pubmed

The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.

CHRNA7 CHRFAM7A

3.29e-052200221143250
Pubmed

Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.

CHRNA7 CHRFAM7A

3.29e-052200216319313
Pubmed

Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.

CHRNA7 CHRFAM7A

3.29e-052200225797465
Pubmed

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.

CHRNA7 CHRFAM7A

3.29e-052200229197398
Pubmed

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

CHRNA7 CHRFAM7A

3.29e-052200238178134
Pubmed

In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

3.29e-052200223325242
Pubmed

Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

3.29e-052200222649244
Pubmed

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.

CHRNA7 CHRFAM7A

3.29e-052200217898229
Pubmed

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.

CHRNA7 CHRFAM7A

3.29e-052200221901321
Pubmed

Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.

CHRNA7 CHRFAM7A

3.29e-052200217935702
Pubmed

Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.

CHRNA7 CHRFAM7A

3.29e-052200220624304
Pubmed

Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.

CHRNA7 CHRFAM7A

3.29e-052200221784975
Pubmed

Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collagen-induced arthritis and adaptive immunity.

CHRNA7 CHRFAM7A

3.29e-052200220659128
Pubmed

Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

CHRNA7 CHRFAM7A

3.29e-052200220843956
Cytoband1p32

ERI3 C8A STIL

2.21e-042720031p32
Cytoband17q22-q23

TSPOAP1 MED13

2.80e-046200217q22-q23
GeneFamilySolute carriers

SLCO3A1 SLC38A10 SLC25A35 SLC24A4 UCP1 UCP3 SLC49A3 SLC22A20P SLC23A2 SLC52A1 FLVCR2 SLC2A5 SLC4A2 SLC22A2 SLC6A20 SLC28A1 SLC16A10

1.39e-0839514217752
GeneFamilyZona pellucida glycoproteins

ZP2 ZP4

3.64e-04414228
GeneFamilyMutS homologs|PWWP domain containing

MSH2 MSH4

6.03e-04514221026
GeneFamilyEF-hand domain containing|Plakins

PPL MACF1

1.66e-0381422939
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM5 GRM6

1.66e-0381422281
GeneFamilyFibronectin type III domain containing

IGFN1 TSPOAP1 OBSCN ROBO3 TRIM36 EPHB1

1.66e-031601426555
GeneFamilySterile alpha motif domain containing|MBT domain containing

MBTD1 L3MBTL1

2.13e-03914221263
GeneFamilyPlexins

PLXNB1 PLXNB3

2.13e-0391422683
GeneFamilyCyclins|Mediator complex

MED13 MED20 MED13L

2.18e-033314231061
GeneFamilyDoublecortin superfamily

DCDC1 DCDC2B

2.64e-031014221369
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 GPR37L1 LPCAT2 KCNJ12 PLXNB1 PLXNB3 FLVCR2 MOXD1 MTOR TMEM268

8.24e-0918019710da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 GPR37L1 LPCAT2 KCNJ12 PLXNB1 PLXNB3 FLVCR2 MOXD1 MTOR TMEM268

8.24e-09180197105b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 GPR37L1 LPCAT2 KCNJ12 PLXNB1 PLXNB3 FLVCR2 MOXD1 MTOR TMEM268

8.24e-091801971050758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

MBTPS1 DCDC2B HMGCR URB1 HEATR1 ARID2 PDCD11 TNFRSF1B IL2RA

9.52e-0817619793de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

FAM178B CUL9 SLC24A4 PRMT9 NLRP1 NEURL1 TMEM268 ST6GALNAC4 EPHB1

2.59e-071981979d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYCBP2 SLCO3A1 HMGCR FREM1 VCAM1 COL6A6 MOXD1 ABCA6 MACF1

2.70e-071991979a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO3A1 ADHFE1 ALDH16A1 C8A SLC2A5 MTOR SLC22A2 ENTPD5

8.56e-07168197835ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MBTPS1 DCDC2B HMGCR URB1 ARID2 PDCD11 TNFRSF1B IL2RA

1.27e-06177197882fdd6185b368f54f03de389427cbe3071d21a99
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ACACB PKHD1 ZNF638 C8A SLC23A2 FLVCR2 WDR59 LIPC

1.91e-061871978f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MBTPS1 MYCBP2 HMGCR URB1 HEATR1 ARID2 MACF1 IL2RA

2.24e-0619119789454f642c3621370fa23640b631301346b300950
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 HMGCR EXTL1 PLXNB3 GPR17 GRM5 OPCML CNTNAP2

3.15e-062001978ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellfacs-Lung-EPCAM-18m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 STIL RNF17 SLC22A2 SERTAD4 QSER1 TNFRSF1B

7.35e-0616019777217730ae14840b935b3bf9aa49becbcbcd8a682
ToppCellfacs-Lung-EPCAM-18m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 STIL RNF17 SLC22A2 SERTAD4 QSER1 TNFRSF1B

7.35e-061601977317ef81460c1a31b51119a6309b11be6a8d4ea3e
ToppCellfacs-Lung-EPCAM-18m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 STIL RNF17 SLC22A2 SERTAD4 QSER1 TNFRSF1B

7.35e-061601977e6191240c93da34fc4431a35ef496edf323cb41e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCIDAS DACT1 IL1R2 VWCE LMX1A NEURL1 TMEM108

9.35e-061661977ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 DCDC2B CFAP65 NEK5 DNAH3 GRM5 NSUN7

1.05e-05169197714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

XIRP1 SYNPO2L SLC49A3 DNAH8 L3MBTL1 IL2RA

1.18e-0511419762cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

XIRP1 SYNPO2L SLC49A3 DNAH8 L3MBTL1 IL2RA

1.18e-051141976fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPR37L1 EXTL1 DCT LPCAT2 PLXNB3 GPR17 MOXD1

1.18e-0517219778d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PSMB3 MED20 COL6A6 MSH4 GRIN2B GTPBP1 L3MBTL1

1.37e-0517619778eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA7 FREM1 RPP25 LPCAT2 TRIM36 CHRFAM7A ENTPD3

1.64e-05181197703a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYCBP2 PTGER3 FREM1 KIAA1586 MED13L MOXD1 ABCA6

1.82e-05184197767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Brain_Myeloid-Cortex|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP7 PTGER3 AP1B1 LPCAT2 RAB3IL1 ZMIZ1 SLC2A5

1.82e-05184197717f63dd671f9ff3dd2860d8de41b05c35c095950
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL DCDC1 DCDC2B CFAP65 NEK5 DNAH3 TCTN2

1.89e-0518519775e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE9A ADAM15 VCAM1 GRIN2B EDN1 TMEM108 EPHB1

1.95e-05186197792092f11ecce22c14f244e42c499af0822977e6f
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 FREM1 VCAM1 COL6A6 MOXD1 ABCA6 TMEM108

2.39e-0519219776f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 MED13 FLVCR2 ZFC3H1 MED13L WDR59 ARID2

2.39e-051921977916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellControl-Treg|Control / Disease group and Cell class

HK3 ADAM15 GBP2 IL1R2 FLVCR2 TNFRSF1B IL2RA

2.39e-0519219773a9a8ac2aa278adde848608f9bb92a002dbb9bcc
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 MED13 FLVCR2 ZFC3H1 MED13L WDR59 ARID2

2.47e-051931977e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FREM1 COL6A6 MOXD1 ABCA6 CD22 CNTNAP2 TMEM108

2.56e-0519419775f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FREM1 VCAM1 COL6A6 MOXD1 ABCA6 CNTNAP2 TMEM108

2.56e-05194197799577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO9 PKHD1 VCAM1 VWCE EDN1 LIPC SLC22A2

2.56e-05194197770185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 FREM1 VCAM1 COL6A6 MOXD1 ABCA6 TMEM108

2.56e-05194197789b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FREM1 VCAM1 COL6A6 MOXD1 ABCA6 CNTNAP2 TMEM108

2.64e-05195197770387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FREM1 COL6A6 MOXD1 ABCA6 CNTNAP2 MACF1 TMEM108

2.73e-0519619771450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HLA-DMB FAM178B SLC24A4 NLRP1 TMEM268 ST6GALNAC4 EPHB1

2.82e-0519719778fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FREM1 VCAM1 COL6A6 ABCA6 CNTNAP2 MACF1 TMEM108

2.82e-0519719770034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FREM1 VCAM1 COL6A6 ABCA6 CNTNAP2 MACF1 TMEM108

2.82e-05197197711a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CERKL DCDC1 MCIDAS GPR37L1 CFAP65 DNAH3 STIL

2.91e-051981977f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellSigmoid-T_cell-Treg|T_cell / Region, Cell class and subclass

CUL9 GBP2 IL1R2 DNAH8 RMND5B TNFRSF1B IL2RA

2.91e-051981977e2d2f9f209f77d0c48cfe3e9902c0ae0795511b2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FREM1 COL6A6 MOXD1 ABCA6 CNTNAP2 MACF1 TMEM108

2.91e-05198197717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 HMGCR EXTL1 PLXNB3 GPR17 GRM5 OPCML

3.01e-051991977333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SLCO3A1 FREM1 VCAM1 COL6A6 MOXD1 ABCA6 MACF1

3.01e-051991977e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 HMGCR EXTL1 PLXNB3 GPR17 GRM5 OPCML

3.01e-051991977e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellControl_saline-Hematopoietic_Myeloid-Dendritic_cells-pDC|Control_saline / Treatment groups by lineage, cell group, cell type

HLA-DMB FAM178B NLRP1 TMEM268 ST6GALNAC4 TNFRSF1B EPHB1

3.01e-05199197734b95e27581bb127e0b921e9c068dc094cb86b37
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLCO3A1 FREM1 VCAM1 COL6A6 MOXD1 ABCA6 MACF1

3.11e-0520019779b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellControl_saline-Hematopoietic_Myeloid-Dendritic_cells|Control_saline / Treatment groups by lineage, cell group, cell type

HLA-DMB FAM178B NLRP1 TMEM268 ST6GALNAC4 TNFRSF1B EPHB1

3.11e-0520019771559844b3116d41a69081e4ee89e64744a760181
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FANCA GRM5 TG CD22 ENTPD6 TMEM108

3.33e-0513719762544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FANCA GRM5 TG CD22 ENTPD6 TMEM108

3.33e-051371976874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SYNPO2L GBP2 URB1 ALDH16A1 ZNF792 SLC6A20

5.74e-0515119764533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SYNPO2L GBP2 URB1 ALDH16A1 ZNF792 SLC6A20

5.74e-051511976edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A ACACB FREM1 SCNN1B PLXNB1 EPHB1

5.74e-051511976f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUGGC FAM178B SLC24A4 NLRP1 TMEM268 EPHB1

5.96e-0515219760c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CUL9 GBP2 IL1R2 DNAH8 TMEM108 IL2RA

6.40e-0515419769200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CUL9 GBP2 IL1R2 DNAH8 TMEM108 IL2RA

6.40e-051541976b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 EXTL1 ACAN GPR17 GRM5 OPCML

6.64e-05155197677fdae85d36efb776db977eb424b32487ef222e4
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Lims2-Tmsb4x_(Lims2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MC5R DCT NEK5 ACAN GPR17

7.11e-059719752b69f41f0aca06da6705376bb6f530ee0e9ac737
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Lims2-Tmsb4x_(Lims2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MC5R DCT NEK5 ACAN GPR17

7.11e-0597197575485ac0dca0dd6a01fe0abf679b984529d46c79
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CERKL PTGER3 LPCAT2 PRMT9 PLXNB3 PAFAH2

7.38e-05158197691d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB TSPOAP1 PTGER3 AARS2 TOPBP1 NLRP1

7.91e-0516019768a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

OBSCN LPCAT2 STIL ZFC3H1 PDCD11 DHX32

8.19e-05161197658381131e651744b5141b202f9d6063f55432db5
ToppCellControl-Treg|World / Disease group and Cell class

HK3 IL1R2 FLVCR2 TMEM108 TNFRSF1B IL2RA

8.19e-051611976ead9f5a491321f9e307f7c97e47a4ca124f59bb6
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADHFE1 C8A SLC2A5 MTOR SLC22A2 ENTPD5

8.47e-0516219766972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)-|Striatum / BrainAtlas - Mouse McCarroll V32

XIRP1 SYNPO2L OTOGL VWCE CD22

8.62e-051011975a05293ccd1de48ed8c7d1417f410d2c4be388c5b
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)|Striatum / BrainAtlas - Mouse McCarroll V32

XIRP1 SYNPO2L OTOGL VWCE CD22

8.62e-051011975b75b000b7899399d1e6aa692d2a4c33b41a1fe18
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDE9A GPRIN1 IL1R2 TG IL2RA SLC16A10

8.76e-051631976bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

HCN2 KCNJ12 PRMT9 CORO7 N4BP2 EPHB1

9.06e-05164197606db4cc064f0765c481ce880207823872c27bfa9
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC1 MCIDAS CFAP65 PKHD1 NSUN7 ENTPD3

9.37e-0516519760c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC1 MCIDAS CFAP65 PKHD1 NSUN7 ENTPD3

9.37e-05165197682530f96aaefe28a13bad0474bbad043f127a86c
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC49A3 DNAH8 ZNF792 NEURL1 EPHB1

9.46e-051031975eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

HLA-DMB IL1R2 RAB3IL1 RNF17 TNFRSF1B IL2RA

9.69e-051661976fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)--|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC PTGER3 IL1R2 LIPC SERAC1

9.90e-0510419757642c6ac1a51b431a8d48d35520930c072a3710e
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC PTGER3 IL1R2 LIPC SERAC1

9.90e-05104197559e982b521610af0532c63b2caf934fa65644b0b
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)-|Striatum / BrainAtlas - Mouse McCarroll V32

NUGGC PTGER3 IL1R2 LIPC SERAC1

9.90e-051041975016704f1d1c43e6d4067ad1d81c22cc660e605d0
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 EXTL1 RPP25 COL6A6 PPL EPHB1

1.00e-041671976c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADHFE1 C8A FLVCR2 SLC2A5 SLC22A2 ENTPD5

1.00e-041671976ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 EXTL1 RPP25 COL6A6 PPL EPHB1

1.00e-041671976351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HK3 MC5R PTGER3 AARS2 GRM6 PAFAH2

1.03e-0416819760e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HK3 MC5R PTGER3 AARS2 GRM6 PAFAH2

1.03e-04168197634722e14f28313f2e4644b3c1861ef12958cee9f
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCDC1 PKHD1 VCAM1 GRM5 LIPC SLC22A2

1.03e-041681976a086c306be430adf0632ba53e98cd8014d2de330
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB MC5R IL1R2 PKHD1 ZMIZ1 PPL

1.07e-041691976a0681317867e31319210a23e56660a53f4529efe
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 MC5R PTGER3 AARS2 GRM6 PAFAH2

1.07e-041691976f2e20049a17eee533d49bd5f24a51962d123d132
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

AP1B1 RAB3IL1 TFAP2C NSUN7 ABCA6 IL2RA

1.07e-041691976241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 MC5R PTGER3 AARS2 GRM6 PAFAH2

1.07e-0416919764c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADHFE1 C8A FLVCR2 SLC2A5 SLC22A2 ENTPD5

1.07e-041691976f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-FDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CERKL MC5R VCAM1 GRIN2B MOXD1 LIPC

1.07e-04169197649a54fb2ea9db5c45e107f304838c536908308bb
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR37L1 DCT NEK5 ACAN PLXNB3 GPR17

1.07e-04169197650cc0f5a022b95986949db63208a627cef9f4a69
ToppCell3'_v3-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

LPCAT2 ROBO3 ATG2B ZMIZ1 MED13L SERAC1

1.10e-0417019764dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCDC1 CFAP65 NEK5 SCNN1B PLXNB1 DNAH3

1.14e-0417119761854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HMGCR CXCL11 VCAM1 ACAD10 SLC2A5 ENTPD6

1.18e-041721976eb199c279fe8a2551121db37e9556893197d33ff
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB ADAM15 MC5R IL1R2 PKHD1 ZMIZ1

1.18e-041721976ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5
ToppCellMS-CD8-proli_CD4|MS / Condition, Cell_class and T cell subcluster

NUGGC SYNPO2L TMEM104 HELB STRN4 ATG2B

1.18e-0417219760b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HMGCR CXCL11 VCAM1 ACAD10 SLC2A5 ENTPD6

1.18e-041721976709c6b77a7a52b873eefb6caca28a41291d384af
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DMB ADAM15 MC5R IL1R2 PKHD1 ZMIZ1

1.18e-0417219763fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM15 GBP2 PTGER3 EDN1 MOXD1 EPHB1

1.29e-0417519762e54961846c65b185d9bd6e305dd81205579d890
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO9 SLC25A35 VCAM1 MED20 POLR1A NEURL1

1.29e-04175197626bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM15 GBP2 PTGER3 EDN1 MOXD1 EPHB1

1.29e-041751976efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB FREM1 PKHD1 GRIN2B CD22 CNTNAP2

1.29e-041751976887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN GPR37L1 NPFFR1 CXCL11 KIAA1586 MICU3

1.33e-04176197630adf8f1638c6244586f8101c2590bb964dfae00
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN GPR37L1 NPFFR1 CXCL11 KIAA1586 MICU3

1.33e-04176197623fa02d4c39e0b8faa1658116d50b6233a952ccc
DiseaseMalignant neoplasm of breast

TRERF1 XIRP1 TBC1D9B HK3 AVPR2 OBSCN ZNF318 ADHFE1 OTOGL SCNN1B PLXNB1 NUP214 ZMIZ1 GRM6 SLC2A5 MTOR N4BP2 SLC28A1 MACF1 DHX32

2.04e-05107418920C0006142
DiseaseAbnormality of the urinary system

TRRAP ZMIZ1

4.08e-0521892C4021821
Diseasehair colour measurement, hair morphology measurement

SPG7 FANCA SLC24A4

5.45e-05121893EFO_0007821, EFO_0007822
Diseaseprediabetes syndrome (biomarker_via_orthology)

UCP1 UCP3 SLC4A2

5.45e-05121893DOID:11716 (biomarker_via_orthology)
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

RAB3IL1 LIPC CNTNAP2

8.94e-05141893OBA_2045142
DiseaseHypercholesterolemia

HMGCR VCAM1 EDN1 LIPC

1.13e-04391894C0020443
Diseasecardioembolic stroke

SYNPO2L LPCAT2 TRIM36 GRM5 OPCML NEURL1 VRTN

1.18e-041701897EFO_1001976
DiseaseIntellectual Disability

TRRAP AP1B1 FDFT1 MED13 GRIN2B ZMIZ1 MED13L POLR3B MTOR MACF1 SERAC1

1.57e-0444718911C3714756
Diseaseurate measurement, bone density

HCN2 FREM1 FANCA A2ML1 DNAH8 SLC23A2 TEX261 PPL TG PAFAH2 TMEM108 ACSM6 EPHB1

1.92e-0461918913EFO_0003923, EFO_0004531
Diseaseureteral obstruction (biomarker_via_orthology)

AVPR2 EDN1 MTOR TNFRSF1B

1.98e-04451894DOID:5199 (biomarker_via_orthology)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KDM4C CHRNA7 FANCA MSH2

1.98e-04451894DOID:3748 (is_implicated_in)
Diseaseend stage renal disease (implicated_via_orthology)

HMGCR LIPC MTOR

2.72e-04201893DOID:783 (implicated_via_orthology)
Diseasecholesterol in small VLDL measurement

HMGCR LIPC ABCA6 SLC22A2

3.74e-04531894EFO_0022228
Diseaseinterstitial cystitis (is_marker_for)

VCAM1 MTOR

4.03e-0451892DOID:13949 (is_marker_for)
DiseaseCholedochal Cyst, Type I

PKHD1 SLC4A2

4.03e-0451892C0009439
DiseaseCholedochal Cyst, Type II

PKHD1 SLC4A2

4.03e-0451892C1257796
DiseaseCholedochal Cyst, Type III

PKHD1 SLC4A2

4.03e-0451892C1257797
DiseaseCholedochal Cyst, Type IV

PKHD1 SLC4A2

4.03e-0451892C1257798
DiseaseCholedochal Cyst, Type V

PKHD1 SLC4A2

4.03e-0451892C1257799
DiseaseCholedochal Cyst

PKHD1 SLC4A2

4.03e-0451892C0008340
DiseaseVitiligo

FANCA MSH2 ZMIZ1 TG IL2RA

4.93e-041011895EFO_0004208
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

ACACB HMGCR DCT FDFT1 LIPC ABCA6 SLC22A2

5.66e-042201897EFO_0004529, EFO_0008317
DiseaseSchizophrenia

MC5R PTGER3 TRRAP CHRNA7 CFAP65 CHRFAM7A GRIN2B GRM5 OPCML LMX1A MTOR CNTNAP2 TNFRSF1B IL2RA HDAC1

5.99e-0488318915C0036341
Diseasephospholipids in small VLDL measurement

HMGCR LIPC ABCA6 SLC22A2

6.01e-04601894EFO_0022146
Diseasecognitive disorder (implicated_via_orthology)

CHRNA7 CHRFAM7A

6.02e-0461892DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRNA7 CHRFAM7A

6.02e-0461892DOID:7148 (biomarker_via_orthology)
DiseaseThyroid Dyshormonogenesis 1

TPO TG

6.02e-0461892C1848805
Diseaseresponse to iloperidone

CERKL SLCO3A1

6.02e-0461892GO_0036287
DiseaseLipid Metabolism, Inborn Errors

LIPC SERAC1

6.02e-0461892C0023772
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

ACACB HMGCR DCT FDFT1 LIPC SLC22A2 MACF1

6.29e-042241897EFO_0004530, EFO_0008317
DiseaseGoiter

TPO TG

8.39e-0471892C0018021
Diseasewellbeing measurement, smoking behaviour measurement

EXTL1 PAFAH2

8.39e-0471892EFO_0005671, EFO_0007869
Diseaselevel of Phosphatidylcholine (18:2_20:3) in blood serum

RAB3IL1 LIPC

8.39e-0471892OBA_2045108
Diseaselow density lipoprotein cholesterol measurement, physical activity

HMGCR SLC25A35 ABCA6 CNTNAP2

8.62e-04661894EFO_0003940, EFO_0004611
Diseasehearing loss

ZNF318 NCAPH2 ACAN LMX1A

9.12e-04671894EFO_0004238
DiseaseEpileptic encephalopathy

NUP214 GRIN2B MTOR

9.24e-04301893C0543888
Diseasehair color

SPG7 DCT FANCA SLC24A4 PKHD1 ZMIZ1 MED13L GRM5

9.33e-043111898EFO_0003924
Diseaseschizophrenia (implicated_via_orthology)

CHRNA7 CHRFAM7A GRM5 MTOR

9.64e-04681894DOID:5419 (implicated_via_orthology)
Diseaseprimary ovarian insufficiency (is_implicated_in)

FANCA MSH4

1.11e-0381892DOID:5426 (is_implicated_in)
Diseasetype 1 diabetes mellitus (is_marker_for)

VCAM1 EDN1 LIPC HDAC1

1.19e-03721894DOID:9744 (is_marker_for)
DiseaseAutosomal Recessive Polycystic Kidney Disease

PKHD1 SLC4A2

1.43e-0391892C0085548
Diseasemarginal zone B-cell lymphoma, multiple sclerosis

ZMIZ1 IL2RA

1.43e-0391892EFO_1000630, MONDO_0005301
Diseaseserum urea measurement

DCDC1 ADAM15 ZNF318 FANCA TNPO1 EPHB1

1.66e-031951896EFO_0009795
Diseasealopecia areata (is_marker_for)

KDM4C HDAC1

1.78e-03101892DOID:986 (is_marker_for)
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

C8A TG

1.78e-03101892EFO_0008321
Diseasewaist circumference

FAM178B SLC24A4 PKHD1 ZMIZ1 MOXD1 N4BP2 SLC22A2 CNTNAP2 TMEM108

1.88e-034291899EFO_0004342
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

ACACB FDFT1 LIPC ABCA6 SLC22A2 MACF1

1.89e-032001896EFO_0004611, EFO_0020945
DiseaseColorectal Carcinoma

HK3 OBSCN DACT1 PKHD1 SCNN1B DNAH8 DNAH3 MSH2 ZMIZ1 ABCA6 NEURL1 VRTN

1.99e-0370218912C0009402
Diseasetriglycerides to total lipids in large VLDL percentage

HMGCR LIPC ABCA6

1.99e-03391893EFO_0022332
Diseasedilated cardiomyopathy (is_marker_for)

PDE9A OBSCN EDN1

1.99e-03391893DOID:12930 (is_marker_for)
DiseaseObesity

ACACB UCP1 UCP3 SLC22A2 ENTPD6 TNFRSF1B

2.13e-032051896C0028754
Diseaseunipolar depression, age at onset

TM9SF2 A2ML1 GRIN2B

2.15e-03401893EFO_0003761, EFO_0004847
Diseasecholesterol in very small VLDL measurement

HMGCR LIPC ABCA6

2.15e-03401893EFO_0022231
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

PKHD1 SLC4A2

2.16e-03111892DOID:0110861 (biomarker_via_orthology)
DiseaseAutoimmune Diseases

TPO HMGCR TG

2.47e-03421893C0004364
Diseasetriglyceride measurement, phospholipid measurement

ACACB DCT FDFT1 LIPC SLC22A2

2.55e-031461895EFO_0004530, EFO_0004639
Diseasenicotine dependence (implicated_via_orthology)

CHRNA7 CHRFAM7A

2.58e-03121892DOID:0050742 (implicated_via_orthology)
Diseasepulmonary embolism (biomarker_via_orthology)

VCAM1 EDN1

2.58e-03121892DOID:9477 (biomarker_via_orthology)
Diseasefree cholesterol to total lipids in very small VLDL percentage

HMGCR LIPC ABCA6

2.64e-03431893EFO_0022290
Diseaseobesity (implicated_via_orthology)

CORO7 MED13 PLXNB1 PLXNB3 MED13L LIPC

2.70e-032151896DOID:9970 (implicated_via_orthology)
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

ACACB HMGCR FDFT1 LIPC ABCA6 SLC22A2

2.70e-032151896EFO_0008317, EFO_0008591
Diseaselipid measurement, lipoprotein measurement

HMGCR FDFT1 LIPC ABCA6

2.71e-03901894EFO_0004529, EFO_0004732
Diseaseconcentration of large LDL particles measurement

HMGCR LIPC ABCA6

2.82e-03441893EFO_0022160
Diseasecholesterol in medium VLDL measurement

HMGCR LIPC ABCA6

2.82e-03441893EFO_0022225
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

HMGCR LIPC ABCA6 SLC22A2 MACF1

2.86e-031501895EFO_0004611, EFO_0020947
Diseasetotal lipids in very small VLDL measurement

HMGCR LIPC ABCA6

3.01e-03451893EFO_0022156
Diseasecholesterol to total lipids in large VLDL percentage

HMGCR LIPC ABCA6

3.01e-03451893EFO_0022236
DiseaseCongenital Hypothyroidism

TPO TG

3.04e-03131892C0010308
DiseaseSkin Abnormalities

AP1B1 FDFT1

3.04e-03131892C0037268
Diseasehypothyroidism (implicated_via_orthology)

TG LIPC

3.04e-03131892DOID:1459 (implicated_via_orthology)
DiseaseHyperlipoproteinemia Type IIb

HMGCR LIPC

3.04e-03131892C1704417
Diseasetotal lipids in small LDL

HMGCR ABCA6 SLC22A2

3.41e-03471893EFO_0022168
Diseasefree cholesterol in small VLDL measurement

HMGCR LIPC ABCA6

3.41e-03471893EFO_0022272
Diseasefree cholesterol in very small VLDL measurement

HMGCR LIPC ABCA6

3.41e-03471893EFO_0022275
Diseasefree cholesterol in medium VLDL measurement

HMGCR ABCA6 SLC22A2

3.41e-03471893EFO_0022269
Diseasecongenital hypothyroidism (implicated_via_orthology)

TPO TG

3.53e-03141892DOID:0050328 (implicated_via_orthology)
Diseaselysophosphatidylcholine 15:0 measurement

PKHD1 LIPC

3.53e-03141892EFO_0020941
Diseasephospholipids:total lipids ratio

HMGCR DCT LIPC ABCA6 SLC22A2 MACF1

3.53e-032271896EFO_0020946
Diseasetotal lipids in lipoprotein particles measurement

HMGCR LIPC SLC22A2

3.62e-03481893EFO_0022309
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

ACACB HMGCR FDFT1 LIPC ABCA6 SLC22A2

3.69e-032291896EFO_0004639, EFO_0008317
Diseasemultiple sclerosis (is_marker_for)

ACAN EDN1 HDAC1

3.84e-03491893DOID:2377 (is_marker_for)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

PLXNB1 PLXNB3 GRIN2B

3.84e-03491893DOID:0060037 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

HLA-DMB IL1R2 ZMIZ1 NEURL1

4.11e-031011894EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseasephospholipids in very small VLDL measurement

HMGCR LIPC ABCA6

4.30e-03511893EFO_0022300
Diseasesuntan

DCT FANCA SLC24A4 GRM5

4.40e-031031894EFO_0004279
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HMGCR FDFT1 LIPC ABCA6 SLC22A2 MACF1

4.53e-032391896EFO_0008317, EFO_0020945
Diseasephospholipids in medium VLDL measurement

HMGCR ABCA6 SLC22A2

4.54e-03521893EFO_0022154
Diseasephospholipids in IDL measurement

HMGCR LIPC ABCA6

4.54e-03521893EFO_0022164
DiseaseHyperlipoproteinemia Type IIa

HMGCR LIPC

4.62e-03161892C0745103
DiseaseCardiovascular Abnormalities

ZMIZ1 EDN1

4.62e-03161892C0243050
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKHD1 MTOR

4.62e-03161892DOID:0110861 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (18:0_18:2) in blood serum

RAB3IL1 LIPC

4.62e-03161892OBA_2045090
Diseasetriglycerides to total lipids in very large VLDL percentage

HMGCR LIPC ABCA6

4.79e-03531893EFO_0022340
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

NUP214 STIL MTOR

4.79e-03531893C1961099
Diseasefree cholesterol in small LDL measurement

HMGCR LIPC ABCA6

4.79e-03531893EFO_0022271
Diseasetype 2 diabetes mellitus (is_implicated_in)

HMGCR UCP1 UCP3 LIPC MTOR

4.99e-031711895DOID:9352 (is_implicated_in)
Diseasemean corpuscular hemoglobin concentration

ZNF318 KCNJ12 ZNF638 SLC22A20P RAB3IL1 SLC23A2 MED13 TNPO1 POLR1A ACAD10 SLC4A2 ABCA6 MACF1 DHX32 SLC16A10

5.18e-03110518915EFO_0004528
Diseaseautoimmune disease

TPO HLA-DMB ZMIZ1 TG IL2RA

5.24e-031731895EFO_0005140
DiseaseCiliopathies

PKHD1 SCNN1B DNAH8 TCTN2

5.55e-031101894C4277690
Diseasefree cholesterol to total lipids in large HDL percentage

HMGCR LIPC ABCA6

5.59e-03561893EFO_0022279

Protein segments in the cluster

PeptideGeneStartEntry
CIVANEAMAPVVNSA

ACSM6

161

Q6P461
EAMAPVVNSAVSDCP

ACSM6

166

Q6P461
FDVCQIVSMGSLFPV

ERV3-1

121

Q14264
LTPFCTELTGIIQAM

ERI3

196

O43414
VGCVEFLSRPTMAFV

SLC4A2

521

P04920
VIPASAVIFGMAVEC

PRMT9

296

Q6P2P2
AVMNPTEVFCSVPGR

TFAP2C

216

Q92754
FFILSLMTCQPGVTA

C8A

6

P07357
VCQDMATVFPAGLAN

ALDH16A1

706

Q8IZ83
CIMEASTDFLPGLNF

ADAM15

376

Q13444
SERMCPIFQISNVTG

GTPBP1

356

O00178
CGQETPLENMLFASF

GPR17

51

Q13304
ICSPFAFTTGMIQII

ABCA6

361

Q8N139
CFSAPVDMATFDLIG

A2ML1

291

A8K2U0
MFGRVQNIPACTSTV

ARID2

801

Q68CP9
GKARSCFAMTEPQVA

ACAD10

786

Q6JQN1
DVSALFPDVVNCMQT

AP1B1

46

Q10567
IANGMVIAFTSEFIP

ANO9

611

A1A5B4
TALMLACEGASPETV

ANKRD24

216

Q8TF21
IFGCLDPVATLAAVM

DHX29

1091

Q7Z478
VLTIAAMVTAPNCFS

DHX32

506

Q7L7V1
LVEFCDQMGLPVDFS

DIS3L2

621

Q8IYB7
MTGVPTENDDFCILF

ATG2B

1481

Q96BY7
ICTIGILMSAPNFVE

CHRNA7

481

P36544
MFTVLTRQPCEQAGL

ENTPD3

1

O75355
ITFLAAGTSVPDCMA

SLC24A4

491

Q8NFF2
AGTSVPDCMASLIVA

SLC24A4

496

Q8NFF2
DVGPCLDFTMQELSV

RAB3IL1

251

Q8TBN0
MTVGQVCSFLVRPSD

RASA1

366

P20936
QFVSLGSMCFPEAVL

QSER1

826

Q2KHR3
GYIPCNMVAEVAVDS

TSPOAP1

1681

O95153
LIGCPMVTDDFVVSG

PSMB3

126

P49720
NTFPEELVMICSSGL

OR4M2B

191

A0A0X1KG70
ATIAPLAIFEFMEQC

ACACB

536

O00763
DGTCVVEFQFMLPSS

ACACB

1316

O00763
AVSDLLVGIFCMPTT

NPFFR1

86

Q9GZQ6
CPSIVQNFAVFPETM

EPHB1

196

P54762
AGTFPMLLTECTEQL

DCDC1

1431

M0R2J8
AFSLPICEGLTQRVM

PTCD3

636

Q96EY7
EGIFLSSMCPINVSA

ENTPD5

31

O75356
VSLSATVALGCMFVP

GRM5

806

P41594
LSACLVAMEPQGSFV

MED13L

1946

Q71F56
PVAVFMVVAQSIVGC

KCNJ12

156

Q14500
TSPSIFPVGFCEINM

MBTD1

436

Q05BQ5
VIASMRECQGFAPDA

MBTPS1

256

Q14703
ITCVFLNVERMAAPT

GTPBP6

171

O43824
MFQPSAVVLQCGSDS

HDAC1

251

Q13547
FQVPMATTEGCLVAS

HMGCR

551

P04035
LQLPMCAVGDTTEAF

CFAP65

251

Q6ZU64
TGMTLPAQKCILDAF

DDX58

671

O95786
FNFCAIPQVMAIATL

FDFT1

286

P37268
GAALVPRQALAVMSC

CORO7

311

P57737
SFQPELGCLQVAAMS

PLXNB1

526

O43157
LGCLQVAAMSPANIS

PLXNB1

531

O43157
QAALCAFPMVELGAS

PLXNB3

311

Q9ULL4
VLPGSSVLFLCDMQE

ISOC2

11

Q96AB3
CTIQSAPAPVMLFVA

KIAA1586

336

Q9HCI6
GCFEAIAPNEFVMRA

LMX1A

96

Q8TE12
AVDRMNPSLVCVASV

L3MBTL1

421

Q9Y468
SMSQVIFALTLPFCG

OR4K2

156

Q8NGD2
SISQIVLTMNLPFCG

OR4L1

156

Q8NH43
NTFPEELVMICSSGL

OR4M1

191

Q8NGD0
NTFPEELVMICSSGL

OR4M2

191

Q8NGB6
MDSAGNKLIAPAVCF

PPL

436

O60437
DCGSVSVAFPITMLL

PTGER3

46

P43115
CDNTGLTRVPMDAFQ

TPO

696

P07202
MDLFCIATGLPRNTT

PDE9A

36

O76083
ASEGEAPVQMEFRSC

NEK5

516

Q6P3R8
PNTGLCFVMREAVTV

NLRP1

1111

Q9C000
ICFLSMGSDPTNQID

DNAH8

3911

Q96JB1
MPCFDTITLVVSDGE

FREM1

971

Q5H8C1
VMCAVAVPEVRFTNV

KDM4C

776

Q9H3R0
TLQECGFNSSLPLVM

LIPC

71

P11150
VPSMVAVCLADGSIA

NUP214

161

P35658
AISSGDLPCMENAVL

GBP2

301

P32456
GATPCLENAMAVLAQ

GBP7

306

Q8N8V2
LFASIECEGQLFMTP

MICU3

151

Q86XE3
MDPSGTFVQCDARAI

PSMA5

156

P28066
FCSVLQGTVMLLAPE

HK3

436

P52790
ICTIGILMSAPNFVE

CHRFAM7A

391

Q494W8
LMITQSRDCGAAAEP

MCIDAS

241

D6RGH6
ISPTGNEAMVPSVCF

MACF1

906

Q9UPN3
PDNFFAAGEDCVVMI

ACAN

2406

P16112
IMSFGLCPVSRQSLD

MOGAT3

161

Q86VF5
PQDSCRVTFLAGDMV

OBSCN

4406

Q5VST9
ILSCEASAVPMAEFQ

OPCML

241

Q14982
MSRCAQAAEVAATVP

LPCAT2

1

Q7L5N7
MAPCEFGVLNSLANV

HLA-DMB

61

P28068
AITFLMVAEPGAAVC

GRM6

636

O15303
VAVQSPMFLLCLTGN

DACT1

276

Q9NYF0
NITVPLAMFCLDATA

DNAH3

656

Q8TD57
MEAFLCEVTSAVQAP

DCDC2B

36

A2VCK2
VSCRAVPFMEVSSLG

GPR37L1

201

O60883
FGLACFANMPVESEL

DENND11

131

A4D1U4
MVASSVGQICTAPAE

FANCA

116

O15360
RLFTGMQTLEPSVVC

CERKL

241

Q49MI3
AIVVFAVCFMPESSQ

BNIP2

166

Q12982
ICSVAQVFILGMPSR

FLVCR2

186

Q9UPI3
LTFIMVPGCQAELCD

IL2RA

11

P01589
SPCEDMGIAVEVFLT

MC5R

31

P33032
PAAVILMLNTEGCSS

CUL9

851

Q8IWT3
PGSFANVSIDMCAII

CNTNAP2

541

Q9UHC6
SALDTLVQAMPVTVC

IGFN1

931

Q86VF2
IPCIAQFSVAMADDS

HEATR1

2046

Q9H583
CFQNTEAGSPTIMLL

HLTF

896

Q14527
AGAQACVSVAVSPMS

GPRIN1

816

Q7Z2K8
MIFSLLFVACQGAPE

EDN1

6

P05305
VIANMFVPEGTQILC

SLC22A20P

411

A6NK97
GIAVVLAMAPFDVAC

SLC25A35

216

Q3KQZ1
GFKTMDFPAVTICNA

SCNN1B

86

P51168
NMVAGAACLASVFIP

SLC22A2

411

O15244
VNSIVGVSVLTMPFC

SLC38A10

16

Q9HBR0
AIATLQQAAAMSFCP

HCN2

726

Q9UL51
VLMAQIGCFVPCESA

MSH2

686

P43246
AVILCATVVQGFPMF

CXCL11

11

O14625
ETFTNLGPIVDMCVV

DDB1

351

Q16531
ALEMICSNPVTVISG

HELB

461

Q8NG08
SPAVEGSQVEFLCMS

CD22

341

P20273
GSQVEFLCMSLANPL

CD22

346

P20273
DIFVEACQGPSMADV

COL6A6

216

A6NMZ7
ACQGPSMADVVFLLD

COL6A6

221

A6NMZ7
NLIMPTCEVGEFTAI

OTOGL

2081

Q3ZCN5
CMELASRGFVVAVPE

PAFAH2

121

Q99487
NGPCLIADTNFDVLM

MED20

81

Q9H944
MPARVVANSGFDVLC

ADHFE1

231

Q8IWW8
MAIVQVTSVFGLPFC

OR10J3

156

Q5JRS4
TEGLASVMAPFVCII

OR1L3

201

Q8NH93
NLSFMDICFTTVIVP

OR1L4

66

Q8NGR5
SVVQTAFAMQLPFCA

OR13C8

156

Q8NGS7
AICTVGRLSSMNPAF

MTOR

711

P42345
SMAQPATRAIVFSGC

RPP25

56

Q9BUL9
PAVSVALGQMARITC

IGLV3-32

26

A0A0A0MS00
ANIVPIAMLVFAACE

MT-ND4L

56

P03901
ALSLGAEACNFMQPV

SYNPO2L

676

Q9H987
AFQPQSGTVEAMCLL

UTP4

476

Q969X6
SGTVEAMCLLAVSPD

UTP4

481

Q969X6
IQQAMFLPVSGESIC

NUGGC

121

Q68CJ6
VPSATVEMFCLEAIV

SERAC1

266

Q96JX3
CFDSSQPFTLVTIGM

TRIM36

626

Q9NQ86
PRIAAQIGDSVMLTC

VCAM1

321

P19320
GFNPDSMCESQVIIR

POLR1A

726

O95602
CPRFSQVLLTEGIMT

BPY2

21

O14599
CSLIGAMAQTPSVII

SLCO3A1

546

Q9UIG8
CADFLVGVTVMPFST

TAAR9

76

Q96RI9
ASPFLVGDDCVSIMN

ENTPD6

206

O75354
MEPSEITNGCFLSIL

NSUN7

491

Q8NE18
LMLAGVVVSCQDITP

FAM178B

601

Q8IXR5
NIFSIVPAILMGCSR

SLC2A5

106

P22732
VPAILMGCSRVATSF

SLC2A5

111

P22732
QAMSPSVAECARAVF

MYCBP2

3021

O75592
PLEIIMSNTACAVGN

MSH4

206

O15457
GFFIQMTTDCIALPS

MSH4

536

O15457
FPVDRSNVLSVACMV

PKHD1

2791

P08F94
SACLVAMEPQGSFVI

MED13

1911

Q9UHV7
AVATEAQVPFLAMAG

SPG7

361

Q9UQ90
SMNRFCEPIVSEGAA

SERTAD4

6

Q9NUC0
APTCVDVLMNFIVAA

EXTL1

581

Q92935
VLVMGVSAFTLQPAA

IL1R2

6

P27930
AMVTQGPEAARDVCS

URB1

156

O60287
STMCIPLAALGTFVQ

SLC6A20

566

Q9NP91
ACQVAQGAMPTFTAE

AARS2

926

Q5JTZ9
VQFQDMCATIGVDPL

SNF8

66

Q96H20
LSVMPFESAVVIVDC

TBC1D9B

676

Q66K14
FIDELASLVPTCNAM

ARNTL

91

O00327
MCQFGLPAEAVEAAN

ADRM1

356

Q16186
VAGQPAFEVCRSMLA

NCAPH2

541

Q6IBW4
SAIPVASMEFAAICL

CNOT10

451

Q9H9A5
AIPNMNVFEATVSCV

RNF17

1176

Q9BXT8
SVGPVAMELAVECSF

SLC49A3

356

Q6UXD7
QLCVVMETGVSPATA

TMEM268

231

Q5VZI3
IAGFCATAMSSPVDV

UCP1

221

P25874
ELFSPGMLVRCVVSS

PDCD11

141

Q14690
ISPEAVISGLNCMSF

STIL

1031

Q15468
TGAMAVTCAQPTDVV

UCP3

126

P55916
SAECVFRMNQAPTVG

ST6GALNAC4

96

Q9H4F1
NMPDAFLTCETVIFA

MOXD1

261

Q6UVY6
AAAGMQLCVDASQPL

NEURL1

416

O76050
GTIAVPFLLADAMCV

SLC23A2

116

Q9UGH3
SAANPLACFLAMGVL

SLC52A1

321

Q9NWF4
VSFASGCVALPVLMN

RMND5B

286

Q96G75
AVPAASCLGDDQVSM

STYXL2

756

Q5VZP5
QMAAPGESVAFQCET

ROBO3

356

Q96MS0
AVPFSLMQVTCSATG

TMEM104

166

Q8NE00
VARVCPVGFSMTETA

VWCE

121

Q96DN2
VMAAFGPSLEECQKA

POLR3B

261

Q9NW08
MLTSPNFILSCGLVV

TEX261

91

Q6UWH6
AQGQFPRVCMTVDSL

DCT

21

P40126
CTMISVNPSGVIQDF

TNPO1

826

Q92973
SLIAASVMAAPCALA

SLC28A1

366

O00337
AMLCSVFEAQSRPQG

WDR59

746

Q6PJI9
LSPANRGALMTCAVV

TM9SF2

391

Q99805
MAAAALRDPAQGCVT

ZNF792

1

Q3KQV3
AVTCLAVDPNGAFLM

STRN4

681

Q9NRL3
NVVAIPGNASMDAVC

TNFRSF1B

186

P20333
ELECSALAVSSPGMV

VRTN

386

Q9H8Y1
TGMTPLEDCVISFSQ

TOPBP1

641

Q92547
EGEFMPVQCKFVNTT

TG

186

P01266
FFCPAMQVEETQGLS

ZP2

136

Q05996
GPLTASMIAVARCFA

TRRAP

3746

Q9Y4A5
LFENCPMGSLAAESI

XIRP1

731

Q702N8
ERFCSVMPANSGLAL

ZFC3H1

1861

O60293
GFQSSVAVRCMLPSA

ZNF318

731

Q5VUA4
NLGDMPVDFCTTRVS

ZNF318

2016

Q5VUA4
ADPLASSVNGMCLDI

TCTN2

546

Q96GX1
TCFPVLMDGNQLSIS

ZNF638

961

Q14966
SACNPVMATQAFVLF

ZP4

221

Q12836
LMVFVAPTLGIAACQ

AVPR2

211

P30518
QRPFEQSLMGCLTVV

ZMIZ1

46

Q9ULJ6
DTGMVLVNPFCQETL

TMEM108

551

Q6UXF1
EMPNCGAVFSSRQAL

TRERF1

1016

Q96PN7
DGCFISIMAPIAFEL

SLC16A10

396

Q8TF71
VGMCTQTEPQDFALL

N4BP2

1011

Q86UW6
FVIVESVDPLSGTCM

GRIN2B

416

Q13224