Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2A14 IL12RB1 IL12RB2 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 UNC5C OR2G2 GPR37L1 OR8H1 CCR3 SEMA6A ADGRV1 GABBR2 OR10R2	3.75e-06	1353	86	19	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 ADGRV1 GABBR2 OR10R2	5.03e-06	884	86	15	GO:0004930
GeneOntologyMolecularFunction	thyroid hormone transmembrane transporter activity	SLC17A4 SLCO4A1 SLC16A10	6.36e-06	9	86	3	GO:0015349
GeneOntologyMolecularFunction	prosaposin receptor activity	GPR37 GPR37L1	1.83e-05	2	86	2	GO:0036505
GeneOntologyMolecularFunction	transporter activity	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 NPC1L1 SLC25A38 SLC17A4 PITPNM3 MFSD2B SLCO4A1 ABCC11 TRPM8 SLC49A3 ATP4A SLC16A10	3.00e-05	1289	86	17	GO:0005215
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A18 SLC6A6 SLC22A18 SLC30A5 SLC17A4 MFSD2B SLCO4A1 ABCC11 ATP4A SLC16A10	3.85e-05	477	86	10	GO:0022804
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A18 SLC6A6 SLC22A18 SLC30A5 SLC17A4 MFSD2B SLCO4A1 SLC16A10	4.14e-05	296	86	8	GO:0015291
GeneOntologyMolecularFunction	pyrimidine-nucleoside phosphorylase activity	TYMP UPP2	5.48e-05	3	86	2	GO:0016154
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A18 SLC6A6 SLC7A3 SLC25A38 SLC16A10	9.07e-05	105	86	5	GO:0015171
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 SLC25A38 SLC17A4 MFSD2B SLCO4A1 ABCC11 TRPM8 SLC49A3 ATP4A SLC16A10	1.42e-04	1180	86	15	GO:0022857
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A6 SLC22A18 SLC7A3 SLC25A38 SLCO4A1 ABCC11 SLC16A10	2.72e-04	293	86	7	GO:0008514
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC6A6 SLC7A3 SLC25A38 SLC16A10	4.55e-04	83	86	4	GO:0015101
GeneOntologyMolecularFunction	symporter activity	SLC6A18 SLC6A6 SLC22A18 SLC17A4 MFSD2B	4.78e-04	150	86	5	GO:0015293
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC6A18 SLC6A6 SLC25A38	7.31e-04	41	86	3	GO:0015175
GeneOntologyMolecularFunction	cytokine receptor activity	IL12RB1 IL12RB2 CXCR4 CCR3	8.19e-04	97	86	4	GO:0004896
GeneOntologyMolecularFunction	lipid transporter activity	NPC1L1 PITPNM3 MFSD2B SLCO4A1 ABCC11	1.59e-03	196	86	5	GO:0005319
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC6A6 SLC7A3 SLC25A38 ABCC11 SLC16A10	2.01e-03	207	86	5	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC6A6 SLC7A3 SLC25A38 ABCC11 SLC16A10	2.06e-03	208	86	5	GO:0005342
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 LRRK2 OR2G2 GPR37L1 MFSD2B OR8H1 CCR3 ADGRV1 GABBR2 OR10R2 ADCY1	1.22e-05	1395	85	18	GO:0007186
GeneOntologyBiologicalProcess	thyroid hormone transport	SLC17A4 SLCO4A1 SLC16A10	1.87e-05	13	85	3	GO:0070327
GeneOntologyBiologicalProcess	cellular response to interleukin-12	IL12RB1 IL12RB2 CD47	1.87e-05	13	85	3	GO:0071349
GeneOntologyBiologicalProcess	response to interleukin-12	IL12RB1 IL12RB2 CD47	3.64e-05	16	85	3	GO:0070671
GeneOntologyCellularComponent	apical part of cell	SLC6A18 SLC6A6 SLC22A18 SLC30A5 SPP1 NPC1L1 SLC17A4 ABCC11 TF ATP4A	1.91e-04	592	88	10	GO:0045177
GeneOntologyCellularComponent	apical plasma membrane	SLC6A18 SLC6A6 SLC22A18 SLC30A5 NPC1L1 SLC17A4 ABCC11 TF ATP4A	2.10e-04	487	88	9	GO:0016324
Domain	MFS	SLC22A18 SLC17A4 MFSD2B SLCO4A1 SLC49A3 SLC16A10	9.81e-06	108	85	6	PS50850
Domain	GPCR_Rhodpsn_7TM	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 OR10R2	9.94e-06	670	85	13	IPR017452
Domain	7tm_1	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 OR10R2	1.11e-05	677	85	13	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 OR10R2	1.26e-05	685	85	13	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 OR10R2	1.38e-05	691	85	13	PS50262
Domain	GPCR_Rhodpsn	OR2A14 OR51F2 NPBWR2 CYSLTR2 OR51Q1 CXCR4 GPR37 GPR85 OR2G2 GPR37L1 OR8H1 CCR3 OR10R2	1.40e-05	692	85	13	IPR000276
Domain	GPR37_orph	GPR37 GPR37L1	2.05e-05	2	85	2	IPR003909
Domain	MFS_dom	SLC22A18 SLC17A4 MFSD2B SLCO4A1 SLC49A3 SLC16A10	3.35e-05	134	85	6	IPR020846
Domain	NfI_DNAbd_pre-N	NFIA NFIX	1.22e-04	4	85	2	PF10524
Domain	CTF_NFI	NFIA NFIX	1.22e-04	4	85	2	PF00859
Domain	CTF_NFI_1	NFIA NFIX	1.22e-04	4	85	2	PS00349
Domain	CTF/NFI	NFIA NFIX	1.22e-04	4	85	2	IPR000647
Domain	CTF_NFI_2	NFIA NFIX	1.22e-04	4	85	2	PS51080
Domain	CTF/NFI_DNA-bd_N	NFIA NFIX	1.22e-04	4	85	2	IPR019548
Domain	CTF/NFI_DNA-bd_CS	NFIA NFIX	1.22e-04	4	85	2	IPR019739
Domain	CTF/NFI_DNA-bd-dom	NFIA NFIX	1.22e-04	4	85	2	IPR020604
Domain	MFS_1	SLC22A18 SLC17A4 SLC49A3 SLC16A10	4.20e-04	77	85	4	PF07690
Domain	MFS	SLC22A18 SLC17A4 SLC49A3 SLC16A10	4.20e-04	77	85	4	IPR011701
Domain	Hematopoietin_rcpt_Gp130_CS	IL12RB1 IL12RB2	4.24e-04	7	85	2	IPR003529
Domain	HEMATOPO_REC_L_F2	IL12RB1 IL12RB2	5.63e-04	8	85	2	PS01353
Domain	MAD_homology1_Dwarfin-type	NFIA NFIX	1.31e-03	12	85	2	IPR003619
Domain	DWA	NFIA NFIX	1.31e-03	12	85	2	SM00523
Domain	MH1	NFIA NFIX	1.31e-03	12	85	2	PF03165
Domain	Chemokine_rcpt	CXCR4 CCR3	2.36e-03	16	85	2	IPR000355
Domain	NA_NEUROTRAN_SYMP_2	SLC6A18 SLC6A6	2.99e-03	18	85	2	PS00754
Domain	SNF	SLC6A18 SLC6A6	3.33e-03	19	85	2	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A18 SLC6A6	3.33e-03	19	85	2	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A18 SLC6A6	3.33e-03	19	85	2	PS50267
Domain	Na/ntran_symport	SLC6A18 SLC6A6	3.33e-03	19	85	2	IPR000175
Domain	Olfact_rcpt	OR2A14 OR51F2 OR51Q1 OR2G2 OR8H1 OR10R2	9.06e-03	393	85	6	IPR000725
Pathway	BIOCARTA_NKT_PATHWAY	IL12RB1 IL12RB2 CXCR4 CCR3	8.12e-06	26	71	4	M4047
Pathway	WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION	IL12RB1 IL12RB2 CXCR4 CCR3	1.28e-05	29	71	4	M39797
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 CES3 SLCO4A1 ABCC11 TRPM8 TF ADCY1 ATP4A SLC16A10	1.48e-05	736	71	14	M27287
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC6A18 SLC6A6 SLC7A3 SLC16A10	1.91e-05	32	71	4	MM14957
Pathway	BIOCARTA_NKT_PATHWAY	IL12RB1 IL12RB2 CXCR4 CCR3	1.91e-05	32	71	4	MM1492
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC6A18 SLC6A6 SLC7A3 SLC16A10	2.16e-05	33	71	4	M188
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 SLCO4A1 SLC16A10	2.50e-05	238	71	8	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 SLCO4A1 SLC16A10	3.45e-05	249	71	8	M5988
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC6A18 SLC6A6 SLC22A18 SLC30A5 SLC39A2	3.93e-05	76	71	5	MM15072
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC6A18 SLC6A6 SLC22A18 SLC30A5 SLC39A2	6.37e-05	84	71	5	M27334
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 CES3 SLCO4A1 TRPM8 TF ATP4A SLC16A10	1.36e-04	681	71	12	MM14985
Pathway	WP_LUNG_FIBROSIS	CYSLTR2 SPP1 CCR3 MMP9	2.81e-04	63	71	4	M39477
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	NPBWR2 CYSLTR2 CXCR4 GPR37 GPR85 GPR37L1 CCR3	3.26e-04	260	71	7	M39397
Pathway	WP_LUNG_FIBROSIS	CYSLTR2 SPP1 CCR3 MMP9	4.95e-04	73	71	4	MM15827
Pathway	REACTOME_INTERLEUKIN_12_SIGNALING	IL12RB1 IL12RB2	5.17e-04	7	71	2	MM17223
Pubmed	Amino acid transport across mammalian intestinal and renal epithelia.	SLC6A18 SLC6A6 SLC7A3 SLC16A10	1.14e-06	31	88	4	18195088
Pubmed	Association between IFNA genotype and the risk of sarcoidosis.	IL12RB1 IL12RB2 SPP1	2.55e-06	11	88	3	15004750
Pubmed	MMP-9-cleaved osteopontin isoform mediates tumor immune escape by inducing expansion of myeloid-derived suppressor cells.	SPP1 MMP9	6.33e-06	2	88	2	28986261
Pubmed	Mesenchymal stem cells overexpressing CXCR4 attenuate remodeling of postmyocardial infarction by releasing matrix metalloproteinase-9.	CXCR4 MMP9	6.33e-06	2	88	2	21671800
Pubmed	Differential regulation of antigen-specific CD8+ T cell responses by IL-12p40 in a dose-dependent manner.	IL12RB1 IL12RB2	6.33e-06	2	88	2	18490715
Pubmed	Assignment of IL12RB1 and IL12RB2, interleukin-12 receptor beta 1 and beta 2 chains, to human chromosome 19 band p13.1 and chromosome 1 band p31.2, respectively, by in situ hybridization.	IL12RB1 IL12RB2	6.33e-06	2	88	2	9284929
Pubmed	CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma.	CXCR4 CD47	6.33e-06	2	88	2	33956406
Pubmed	[CXC chemokine receptor 4 regulates breast cancer cell cycle through S phase kinase associated protein 2].	CXCR4 SKP2	6.33e-06	2	88	2	29256223
Pubmed	Effector T-cell differentiation during viral and bacterial infections: Role of direct IL-12 signals for cell fate decision of CD8(+) T cells.	IL12RB1 IL12RB2	6.33e-06	2	88	2	19548244
Pubmed	Osteopontin facilitates invasion in human trophoblastic cells via promoting matrix metalloproteinase-9 in vitro.	SPP1 MMP9	6.33e-06	2	88	2	26823725
Pubmed	Glioblastoma Factors Increase the Migration of Human Brain Endothelial Cells In Vitro by Increasing MMP-9/CXCR4 Levels.	CXCR4 MMP9	6.33e-06	2	88	2	32366418
Pubmed	Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination.	GPR37 GPR37L1	6.33e-06	2	88	2	28642167
Pubmed	Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.	SPP1 MMP9	6.33e-06	2	88	2	19010864
Pubmed	Association study between interleukin-12 receptor beta1/beta2 genes and type 1 diabetes or asthma in the Japanese population.	IL12RB1 IL12RB2	6.33e-06	2	88	2	12719941
Pubmed	Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1.	SPP1 NPC1L1	6.33e-06	2	88	2	28627641
Pubmed	Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system.	IL12RB1 IL12RB2	6.33e-06	2	88	2	12574388
Pubmed	CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis.	SPP1 MMP9	6.33e-06	2	88	2	23071279
Pubmed	GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells.	GPR37 GPR37L1	6.33e-06	2	88	2	30423289
Pubmed	GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.	GPR37 GPR37L1	6.33e-06	2	88	2	28688853
Pubmed	Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma.	SMPD1 MMP9	6.33e-06	2	88	2	17540003
Pubmed	Characterization of two novel mutations in IL-12R signaling in MSMD patients.	IL12RB1 IL12RB2	6.33e-06	2	88	2	31158284
Pubmed	Coexpression of CXCR4 and MMP9 predicts lung metastasis and poor prognosis in resected osteosarcoma.	CXCR4 MMP9	6.33e-06	2	88	2	26546437
Pubmed	Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity.	FBXL18 LRRK2	6.33e-06	2	88	2	27890708
Pubmed	Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.	IL12RB1 IL12RB2	6.33e-06	2	88	2	7911493
Pubmed	Modification of osteopontin and MMP-9 levels in patients with psoriasis on anti-TNF-α therapy.	SPP1 MMP9	6.33e-06	2	88	2	22684781
Pubmed	[Significance of expression of chemokine receptor and matrix metalloproteinase in small cell lung cancer].	CXCR4 MMP9	6.33e-06	2	88	2	22490156
Pubmed	IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo.	IL12RB1 IL12RB2	6.33e-06	2	88	2	19544494
Pubmed	Mouse Mutants of Gpr37 and Gpr37l1 Receptor Genes: Disease Modeling Applications.	GPR37 GPR37L1	6.33e-06	2	88	2	35457105
Pubmed	A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis.	SPP1 MMP9 SKP2 ATP4A	1.18e-05	55	88	4	34237211
Pubmed	Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid.	SPP1 APOH TF	1.24e-05	18	88	3	16199891
Pubmed	Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration.	IL12RB1 IL12RB2	1.90e-05	3	88	2	20212068
Pubmed	Altered chemokine receptor expression in papillary thyroid cancer.	CXCR4 CCR3	1.90e-05	3	88	2	19731977
Pubmed	GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.	GPR37 GPR37L1	1.90e-05	3	88	2	23690594
Pubmed	Novel envelope determinants for CCR3 use by human immunodeficiency virus.	CXCR4 CCR3	1.90e-05	3	88	2	17041228
Pubmed	An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells.	SPP1 MMP9	1.90e-05	3	88	2	16709900
Pubmed	Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosis.	CXCR4 MMP9	1.90e-05	3	88	2	17463394
Pubmed	Direct interaction of STAT4 with the IL-12 receptor.	IL12RB1 IL12RB2	1.90e-05	3	88	2	10415122
Pubmed	Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains.	CXCR4 CCR3	1.90e-05	3	88	2	9765440
Pubmed	Cyclin G associated kinase interacts with interleukin 12 receptor beta2 and suppresses interleukin 12 induced IFN-gamma production.	IL12RB1 IL12RB2	1.90e-05	3	88	2	17937931
Pubmed	The prognostic value of CXCR4, MMP-2 and MMP-9 in tongue squamous carcinoma.	CXCR4 MMP9	1.90e-05	3	88	2	31263828
Pubmed	Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.	NFIA NFIX	1.90e-05	3	88	2	31128945
Pubmed	A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.	TYMP UPP2	1.90e-05	3	88	2	21855639
Pubmed	Deregulation of the CXCL12/CXCR4 axis in methotrexate chemotherapy-induced damage and recovery of the bone marrow microenvironment.	CXCR4 MMP9	1.90e-05	3	88	2	22220905
Pubmed	[Correlation study between OPN, CD44v6, MMP-9 and distant metastasis in laryngeal squamous cell carcinoma].	SPP1 MMP9	1.90e-05	3	88	2	23373240
Pubmed	Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma.	SPP1 MMP9	1.90e-05	3	88	2	22410369
Pubmed	Osteopontin-stimulated expression of matrix metalloproteinase-9 causes cardiomyopathy in the mdx model of Duchenne muscular dystrophy.	SPP1 MMP9	1.90e-05	3	88	2	21810612
Pubmed	A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.	SPP1 MMP9	1.90e-05	3	88	2	20207476
Pubmed	Missense mutations of the interleukin-12 receptor beta 1(IL12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea.	IL12RB1 IL12RB2	1.90e-05	3	88	2	12743658
Pubmed	Induction of vascular endothelial growth factor and matrix metalloproteinase-9 via CD47 signaling in neurovascular cells.	CD47 MMP9	1.90e-05	3	88	2	20364320
Pubmed	LRRK2, GBA and SMPD1 Founder Mutations and Parkinson's Disease in Ashkenazi Jews.	LRRK2 SMPD1	1.90e-05	3	88	2	27449028
Pubmed	NF‑κB inhibition is associated with OPN/MMP‑9 downregulation in cutaneous melanoma.	SPP1 MMP9	1.90e-05	3	88	2	28075446
Pubmed	Interrelationship of Osteopontin, MMP-9 and ADAMTS4 in Patients With Osteoarthritis Undergoing Total Joint Arthroplasty.	SPP1 MMP9	1.90e-05	3	88	2	33350314
Pubmed	Clinical Significance of Circulating Osteopontin Levels in Patients With Lung Cancer and Correlation With VEGF and MMP-9.	SPP1 MMP9	1.90e-05	3	88	2	27624849
Pubmed	Identification of a heteromeric complex that promotes DNA replication origin firing in human cells.	TOPBP1 MTBP	1.90e-05	3	88	2	23704573
Pubmed	Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia.	IL12RB1 IL12RB2	1.90e-05	3	88	2	14568135
Pubmed	Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation.	SPP1 MMP9	1.90e-05	3	88	2	19602039
Pubmed	IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1.	IL12RB1 IL12RB2	1.90e-05	3	88	2	14662893
Pubmed	Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse olfactory organ.	GPR37 GPR37L1	1.90e-05	3	88	2	37075680
Pubmed	Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis.	CXCR4 MMP9	1.90e-05	3	88	2	17916907
Pubmed	Genetic variations of IL-12B, IL-12Rβ1, IL-12Rβ2 in Behcet's disease and VKH syndrome.	IL12RB1 IL12RB2	1.90e-05	3	88	2	24859272
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	SLC6A6 IL12RB1 IL12RB2 GPR37 GABBR2	3.26e-05	143	88	5	20424473
Pubmed	Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS.	CXCR4 CCR3	3.79e-05	4	88	2	10415069
Pubmed	Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice.	NFIA NFIX	3.79e-05	4	88	2	28295292
Pubmed	CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation.	GPR37 GABBR2	3.79e-05	4	88	2	25977097
Pubmed	Plasminogen regulates stromal cell-derived factor-1/CXCR4-mediated hematopoietic stem cell mobilization by activation of matrix metalloproteinase-9.	CXCR4 MMP9	3.79e-05	4	88	2	21719761
Pubmed	Gene regulatory networks controlling vertebrate retinal regeneration.	NFIA NFIX	3.79e-05	4	88	2	33004674
Pubmed	IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.	IL12RB1 IL12RB2	3.79e-05	4	88	2	19306359
Pubmed	Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines.	SPP1 CXCR4	3.79e-05	4	88	2	21909361
Pubmed	NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation.	NFIA NFIX	3.79e-05	4	88	2	29247144
Pubmed	IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.	IL12RB1 IL12RB2	3.79e-05	4	88	2	19100623
Pubmed	Study of the HIV-1 receptors CD4, CXCR4, CCR5 and CCR3 in the human and rat testis.	CXCR4 CCR3	3.79e-05	4	88	2	11994538
Pubmed	CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1α, CXCR4, Osteopontin and Cathepsin K.	SPP1 CXCR4	3.79e-05	4	88	2	25809793
Pubmed	Regulatory role of DC-derived osteopontin in systemic allergen sensitization.	IL12RB1 SPP1	3.79e-05	4	88	2	19830723
Pubmed	CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.	CXCR4 MMP9	3.79e-05	4	88	2	16114056
Pubmed	CXCR4 promotes oral squamous cell carcinoma migration and invasion through inducing expression of MMP-9 and MMP-13 via the ERK signaling pathway.	CXCR4 MMP9	3.79e-05	4	88	2	21205837
Pubmed	Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia.	CXCR4 CCR3	3.79e-05	4	88	2	11115360
Pubmed	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.	NFIA NFIX	3.79e-05	4	88	2	9056636
Pubmed	Functional impact of HIV coreceptor-binding site mutations.	CXCR4 CCR3	3.79e-05	4	88	2	16631222
Pubmed	Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression.	SPP1 MMP9	3.79e-05	4	88	2	26381542
Pubmed	Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.	MMP9 SKP2	3.79e-05	4	88	2	24986570
Pubmed	Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.	SPP1 MMP9	3.79e-05	4	88	2	17493236
Pubmed	Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease.	CXCR4 CCR3	3.79e-05	4	88	2	10590105
Pubmed	Nuclear factor one transcription factors as epigenetic regulators in cancer.	NFIA NFIX	3.79e-05	4	88	2	28076901
Pubmed	Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases.	SPP1 MMP9	3.79e-05	4	88	2	31411676
Pubmed	Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya.	IL12RB1 IL12RB2	3.79e-05	4	88	2	20350312
Pubmed	Transcription factor NF 1 expression in involuting mammary gland.	NFIA NFIX	3.79e-05	4	88	2	10959417
Pubmed	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.	NFIA NFIX	3.79e-05	4	88	2	7590749
Pubmed	Patterns of metastatic spread in early breast cancer.	SPP1 CXCR4	3.79e-05	4	88	2	23726130
Pubmed	Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration.	CHODL MMP9	3.79e-05	4	88	2	24462097
Pubmed	Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.	NFIA NFIX	3.79e-05	4	88	2	9052991
Pubmed	Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.	NFIA NFIX	3.79e-05	4	88	2	12568726
Pubmed	CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 and ERK1/2.	CXCR4 MMP9	3.79e-05	4	88	2	26261552
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NFIA CDK12 ADNP KDM1A	6.04e-05	83	88	4	28794006
Pubmed	Differential associations between the cytoplasmic regions of the interleukin-12 receptor subunits beta1 and beta2 and JAK kinases.	IL12RB1 IL12RB2	6.30e-05	5	88	2	9038232
Pubmed	Human adolescent nephronophthisis: gene locus synteny with polycystic kidney disease in pcy mice.	TOPBP1 TF	6.30e-05	5	88	2	11134256
Pubmed	Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting.	SLC22A18 ZNF195	6.30e-05	5	88	2	10369881
Pubmed	Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans.	IL12RB1 IL12RB2	6.30e-05	5	88	2	20060272
Pubmed	Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide.	IL12RB1 IL12RB2	6.30e-05	5	88	2	19587012
Pubmed	The influence of transforming growth factor-α, cyclooxygenase-2, matrix metalloproteinase (MMP)-7, MMP-9 and CXCR4 proteins involved in epithelial-mesenchymal transition on overall survival of patients with gastric cancer.	CXCR4 MMP9	6.30e-05	5	88	2	22582975
Pubmed	Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.	NFIA NFIX	6.30e-05	5	88	2	19706729
Interaction	IPPK interactions	SLC7A3 SLC30A5 CDK12 CXCR4 CD47 RETREG3	6.78e-06	116	80	6	int:IPPK
Cytoband	1p31.3-p31.2	IL12RB2 NFIA	1.09e-05	3	88	2	1p31.3-p31.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q22	SPP1 UNC5C HSD17B13	4.00e-04	74	88	3	chr4q22
Cytoband	4q22.1	SPP1 HSD17B13	1.15e-03	26	88	2	4q22.1
Cytoband	7q31	GPR37 GPR85	1.24e-03	27	88	2	7q31
Cytoband	17q24.2	NOL11 APOH	1.53e-03	30	88	2	17q24.2
Cytoband	3q22.1	TOPBP1 TF	2.98e-03	42	88	2	3q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	SLC22A18 OR51F2 OR51Q1 ZNF195 SMPD1	4.67e-03	564	88	5	chr11p15
GeneFamily	Solute carriers	SLC6A18 SLC6A6 SLC22A18 SLC7A3 SLC30A5 SLC39A2 SLC25A38 SLC17A4 SLCO4A1 SLC49A3 SLC16A10	2.76e-07	395	69	11	752
Coexpression	LU_TUMOR_ANGIOGENESIS_UP	SPP1 CXCR4 MMP9 TYMP	1.30e-06	25	86	4	M9946
Coexpression	GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	FNDC7 CHODL MFSD2B CCR3 BTLA MMP9	1.76e-05	165	86	6	M9105
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 KIR3DX1 SH2D1B CXCR4 DENND2D SKP2	2.63e-06	197	88	6	52246d1354c4e2b13d48c878643edf843d2b50d2
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|343B / Donor, Lineage, Cell class and subclass (all cells)	IL12RB1 SLC39A2 SH2D1B CXCR4 DENND2D	1.37e-05	154	88	5	886e7cd01cb48ca3e97debeea2b1f100b09d47e6
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB2 CYSLTR2 SH2D1B CXCR4 CCR3	1.55e-05	158	88	5	607a13a3991953c1a98cc2fe90099b60487ca4f1
ToppCell	facs-GAT-Fat-18m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 SLC17A4 HSD17B2 TMEM139	2.09e-05	168	88	5	d6c8056b7d6b937bb91e6b33beeb1075dce1685c
ToppCell	facs-GAT-Fat-18m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 SLC17A4 HSD17B2 TMEM139	2.09e-05	168	88	5	7102c52bf1b2ba67bb3700932181a2e0a6627711
ToppCell	facs-GAT-Fat-18m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 SLC17A4 HSD17B2 TMEM139	2.09e-05	168	88	5	68a2f9fd53b54023241acd1620cf24226f639c1b
ToppCell	LPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CCR3	2.47e-05	174	88	5	61aa89b56ebda0eba1ba675d5f036992967f670f
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CCR3	2.75e-05	178	88	5	7905621f5b2aa55324c5592d1d2fef763a5fa41f
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CCR3	2.75e-05	178	88	5	f914092c20130207193f97c6044ae61a9a440a86
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CCR3	2.83e-05	179	88	5	de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CCR3	2.83e-05	179	88	5	def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL12RB1 IL12RB2 KIR3DX1 SH2D1B DENND2D	2.98e-05	181	88	5	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB2 EYS SH2D1B CXCR4 DENND2D	3.06e-05	182	88	5	09d0793245d3d77ab5fc384c0b62637f736da50b
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC6A18 SLCO4A1 ADGRV1 UPP2 TF	3.14e-05	183	88	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 IL12RB2 SH2D1B CXCR4 DENND2D	3.48e-05	187	88	5	b5c8322ee728303425be677aa0c36fa552fd0f59
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPP1 GPR37 GPR37L1 PLPPR1 TF	3.48e-05	187	88	5	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	wk_08-11-Hematologic-Myeloid-DC1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 CYSLTR2 LRRK2 BTLA TYMP	3.48e-05	187	88	5	2907cc0b8789c5e1468917caa21fa0feb025305e
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 IL12RB2 SH2D1B CXCR4 DENND2D	3.57e-05	188	88	5	624426815b789f0f35c327b8c3c0c05ba3aa7d98
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB2 SH2D1B CXCR4 TRPM8 DENND2D	3.66e-05	189	88	5	5a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell	PSB-critical-LOC-Lymphoid-NK\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IL12RB2 CYSLTR2 KIR3DX1 SH2D1B CXCR4	3.76e-05	190	88	5	e1b5d76edd4c1b95c0a7b94284a65043ab895e67
ToppCell	PCW_10-12-Immune_Lymphocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 IL12RB2 SH2D1B CXCR4 DENND2D	3.76e-05	190	88	5	9b56763d62e1ed50006a5b90b160c5a82aab515b
ToppCell	Control-Myeloid-MoAM5,_CCL3L1\|Myeloid / Condition, Lineage and Cell class	SPP1 CXCR4 SLCO4A1 MMP9 SLC16A10	4.15e-05	194	88	5	96400477d130b2403ed81c229e4e4182cc2cdc14
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB2 KIR3DX1 SH2D1B CXCR4 DENND2D	4.15e-05	194	88	5	3fe32e38c95135d152acb1624fec1623339e144a
ToppCell	Control-Myeloid-MoAM5,_CCL3L1\|Control / Condition, Lineage and Cell class	SPP1 CXCR4 SLCO4A1 MMP9 SLC16A10	4.15e-05	194	88	5	a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB1 EYS SH2D1B CXCR4 DENND2D	4.15e-05	194	88	5	da88e8c11e55df296d2533f1d1575779cdf3edd7
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB1 EYS SH2D1B CXCR4 DENND2D	4.25e-05	195	88	5	441345d33f839a9e9222e790752b5603ff572bf2
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB2 SH2D1B CXCR4 TRPM8 MMP9	4.68e-05	199	88	5	3bac69726153e988a7f36613ee280c74d2fa7545
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 KIR3DX1 SH2D1B CXCR4 DENND2D	4.68e-05	199	88	5	dfb89ff7b075420c63ead0f802d93a5f82fb7c28
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 KIR3DX1 SH2D1B CXCR4 DENND2D	4.79e-05	200	88	5	993b0856964d611af8d8cd1ea4d609fa3ede65ea
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CXCR4	4.79e-05	200	88	5	72e1cc0b222df3ab76164524676e91628e237995
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CHODL GPR85 UNC5C GPR37L1 ADCY1	4.79e-05	200	88	5	a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CXCR4	4.79e-05	200	88	5	44674ccfd1ad4ac45968484d70220bc0506e2651
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 IL12RB2 KIR3DX1 SH2D1B CXCR4	4.79e-05	200	88	5	b5d00efb4286ae63cb081ef774aa0b0ff90d6c8a
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB1 KIR3DX1 SH2D1B CXCR4 DENND2D	4.79e-05	200	88	5	2efea0f2ac28d973182763d7667614204718d624
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM234A DYNC1LI1 DENND2D SKP2	8.28e-05	116	88	4	f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FIBCD1 SEMA6A MMP9 PLPPR1	1.01e-04	122	88	4	eae9d94f8510ac0f434942451d55c7260977b178
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC22A18 SPP1 SLC49A3 HSD17B2	1.04e-04	123	88	4	64a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SPP1 CXCR4 FIBCD1 HSD17B2	1.25e-04	129	88	4	6bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Rab3b_(Cerebellum_basket_cells_2)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MFSD2B TRPM8 BTLA	1.33e-04	50	88	3	71918067d244fa6fee6ed0dd5a2a52d46441f815
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Rab3b_(Cerebellum_basket_cells_2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MFSD2B TRPM8 BTLA	1.33e-04	50	88	3	4fbda6dd9a723484b82935a7300c32e2d88964af
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC22A18 SPP1 SERINC4 HSD17B2	1.49e-04	135	88	4	7e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC22A18 SPP1 SERINC4 HSD17B2	1.49e-04	135	88	4	4cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC22A18 SPP1 SERINC4 HSD17B2	1.49e-04	135	88	4	6bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC22A18 SPP1 SERINC4 HSD17B2	1.49e-04	135	88	4	97989546826bf3739e1b86a10832a457fd37c5d2
ToppCell	TCGA-Bile_Duct\|World / Sample_Type by Project: Shred V9	NPC1L1 SLC17A4 APOH HSD17B2	1.71e-04	140	88	4	ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell	Bronchial_Biopsy-Epithelial-Goblet_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC39A2 SLCO4A1 UPP2 TF	1.96e-04	145	88	4	e932361734839c14ffa0c1e028dcef9c833f884f
ToppCell	Bronchial_Biopsy-Epithelial-Goblet_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC39A2 SLCO4A1 UPP2 TF	2.01e-04	146	88	4	a4f2e3ea79e7154873c01739672ec6454547e6a6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NFIA ALDH16A1 HSD17B13 PLPPR1	2.12e-04	148	88	4	a261c6d3d9cf0311c053fca66c37d39e66db6ad8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	NFIA ALDH16A1 HSD17B13 PLPPR1	2.12e-04	148	88	4	c0237ba7d4040b6a497094b362dfb8b3a97a7d06
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL18 CXCR4 ADGRV1 MMP9	2.23e-04	150	88	4	34774b015adecc2be56a471fda8994e89a6ad93e
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	IL12RB2 SH2D1B CES3 SLC16A10	2.52e-04	155	88	4	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC17A4 CES3 HSD17B2	2.59e-04	156	88	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	GPR37 LRRK2 PITPNM3 ADGRV1	2.65e-04	157	88	4	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPP1 PLA2G3 UNC5C PLPPR1	2.85e-04	160	88	4	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	PLA2G3 LRRK2 APOH PLPPR1	2.85e-04	160	88	4	ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	PLA2G3 LRRK2 APOH PLPPR1	2.85e-04	160	88	4	b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPP1 PLA2G3 UNC5C PLPPR1	2.85e-04	160	88	4	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYSLTR2 PLA2G3 ADCY1 ADAM22	2.92e-04	161	88	4	176a4a72bb4892932da3c834d1fea5e211847f92
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	UGT1A8 UNC5C SLC17A4 HSD17B2	2.98e-04	162	88	4	7f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCell	facs-Heart-RA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSD17B13 SLC17A4 HSD17B2 TMEM139	3.06e-04	163	88	4	13557be854878abc1bcdab909b49b8292d064145
ToppCell	facs-Heart-RA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSD17B13 SLC17A4 HSD17B2 TMEM139	3.06e-04	163	88	4	6c1d1646410e785886d2de103b4b12f73e91edff
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A3 SLC39A2 MFSD2B TMEM139	3.06e-04	163	88	4	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh\|GI_large-bowel / Manually curated celltypes from each tissue	NFIA CXCR4 ADGRV1 SKP2	3.06e-04	163	88	4	4104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A3 SLC39A2 MFSD2B ADAM22	3.06e-04	163	88	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-mature_NK_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 CXCR4 DENND2D SLC16A10	3.13e-04	164	88	4	22f37c39fdce2cf6dc72c6db619537d4b0234839
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM234A SLC17A4 CES3 ADGRV1	3.13e-04	164	88	4	d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 HSD17B2 TMEM139	3.13e-04	164	88	4	2a00515d91ea03efcfc2a3d3c805dc2711867fcd
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 HSD17B2 TMEM139	3.20e-04	165	88	4	ce79d217df88035457cd58f679e72dd98722ae22
ToppCell	facs-Kidney-nan-3m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 IL12RB2 CYSLTR2 CXCR4	3.20e-04	165	88	4	ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCell	11.5-Airway-RBC-RBC\|Airway / Age, Tissue, Lineage and Cell class	IL12RB2 PLA2G3 MFSD2B TF	3.20e-04	165	88	4	8618b2c5659aa70c7c9d6e51a227ac612b4ad17b
ToppCell	11.5-Airway-RBC\|Airway / Age, Tissue, Lineage and Cell class	IL12RB2 PLA2G3 MFSD2B TF	3.20e-04	165	88	4	46042340a373adaf1c439b2301e02fbae3e31a4f
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPP1 HSD17B13 SLC17A4 SLC49A3	3.20e-04	165	88	4	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-1\|TCGA-Ovary / Sample_Type by Project: Shred V9	SEMA6A ADGRV1 SKP2 SLC16A10	3.20e-04	165	88	4	2ca1154a8692af311d99a4d3aa2f2ac3d23a4310
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC49A3 HSD17B2 TMEM139	3.27e-04	166	88	4	22b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCell	facs-Heart-RV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 CXCR4 DENND2D	3.27e-04	166	88	4	c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCell	facs-Heart-RV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 CXCR4 DENND2D	3.27e-04	166	88	4	ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC22A18 SPP1 DENND2D TF	3.43e-04	168	88	4	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	healthy_donor-Myeloid-Monocytic-Neutrophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SLC6A6 LRRK2 CCR3 MMP9	3.43e-04	168	88	4	04259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCell	Control-NK\|Control / Disease group and Cell class	SH2D1B NFIX SLCO4A1 SLC16A10	3.43e-04	168	88	4	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A18 ALDH16A1 HSD17B2 UPP2	3.43e-04	168	88	4	35ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 SPRY4 HSD17B13	3.50e-04	169	88	4	630d921aa8fb5681d06a4e09b833855c374be484
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 SPRY4 HSD17B13	3.50e-04	169	88	4	468284d4a3a0557aed04eadb1aba2317babc6904
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 SPRY4 HSD17B13	3.50e-04	169	88	4	6f765e142d127545e622fe24b5287cd6e9706ccc
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 HSD17B13 HSD17B2 TMEM139	3.58e-04	170	88	4	75b0486620cab838d3feb1c3aa965b487a906618
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-mature_NK_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 IL12RB2 CYSLTR2 MMP9	3.66e-04	171	88	4	d322cc042a6f4b4aa8ef80ae977edbce9e266d48
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIX GPR37L1 MFSD2B SEMA6A	3.75e-04	172	88	4	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC22A18 SERINC4 ZNF195 GNL1	3.75e-04	172	88	4	80b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 DENND2D MEAK7	3.75e-04	172	88	4	10a1d1838492b8ce6dea08844353b51571432c56
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 CYSLTR2 DENND2D MEAK7	3.75e-04	172	88	4	d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIX GPR37L1 MFSD2B SEMA6A	3.75e-04	172	88	4	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 SH2D1B CCR3	3.83e-04	173	88	4	fde1fabb8d13d05998ac3f21ecb1fde6a7a2f337
ToppCell	18-Airway-Immune-Hematopoietic,_Natural_Killer_Cell\|Airway / Age, Tissue, Lineage and Cell class	IL12RB1 IL12RB2 SH2D1B DENND2D	3.83e-04	173	88	4	054cb468a2a10a96aa1d971618993f6777569e14
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 SH2D1B CCR3	3.83e-04	173	88	4	dcde3252ff96448d3a61039a4948c74ad321a218
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC17A4 HSD17B2 TMEM139	3.91e-04	174	88	4	2fbdb62e269acf4447b171700a615e878dde7f9f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC17A4 HSD17B2 TMEM139	3.91e-04	174	88	4	7c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCell	TCGA-Colorectal-Recurrent_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HSD17B13 TRPM8 APOH TF	4.00e-04	175	88	4	7f74961436f88c0e380819095e6104489914d765
ToppCell	facs-Heart-RA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 CYSLTR2 CCR3 DENND2D	4.00e-04	175	88	4	db977f18a71845ecb16ee3e6b3fb03dea4a1a8bc
ToppCell	TCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HSD17B13 TRPM8 APOH TF	4.00e-04	175	88	4	bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell	facs-Heart-RA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB2 CYSLTR2 CCR3 DENND2D	4.00e-04	175	88	4	7b38cbd73be26cf33393c6e6c804d62856a91ec3
ToppCell	LPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 IL12RB2 SH2D1B CCR3	4.00e-04	175	88	4	98cb577df466700e72d1bbc6689205ccf2e7fcba
Drug	2,4-dichloronitrobenzene	IL12RB1 IL12RB2 CXCR4 PHIP	3.49e-07	16	87	4	CID000011899
Disease	Neoplasm Invasiveness	CXCR4 SMPD1 MMP9 TF KDM1A TMEM139	1.47e-05	184	84	6	C0027626
Disease	Abnormality of the eye	SLCO4A1 SEMA6A	2.40e-05	3	84	2	HP_0000478
Disease	Niemann-Pick disease (implicated_via_orthology)	NPC1L1 SMPD1	4.79e-05	4	84	2	DOID:14504 (implicated_via_orthology)
Disease	Alveolitis, Fibrosing	CYSLTR2 SPP1 CCR3 MMP9	9.46e-05	83	84	4	C4721507
Disease	Pulmonary Fibrosis	CYSLTR2 SPP1 CCR3 MMP9	1.04e-04	85	84	4	C0034069
Disease	carbohydrate measurement	EYS MEAK7 KDM1A	3.09e-04	46	84	3	EFO_0004998
Disease	glomerulosclerosis (biomarker_via_orthology)	SPP1 MMP9	3.55e-04	10	84	2	DOID:0050851 (biomarker_via_orthology)
Disease	Leukoencephalopathy	SPP1 TYMP	4.33e-04	11	84	2	C0270612
Disease	diabetic retinopathy (is_marker_for)	APOH MMP9 KDM1A	4.97e-04	54	84	3	DOID:8947 (is_marker_for)
Disease	xanthine measurement	EYS ADAM22	6.12e-04	13	84	2	EFO_0010548
Disease	prostate carcinoma (is_implicated_in)	SPP1 SKP2	6.12e-04	13	84	2	DOID:10286 (is_implicated_in)
Disease	Asthma, Aspirin-Induced	CYSLTR2 CCR3	6.12e-04	13	84	2	C1319853
Disease	myocardial infarction (implicated_via_orthology)	CCR3 APOH MMP9	8.95e-04	66	84	3	DOID:5844 (implicated_via_orthology)
Disease	rheumatoid arthritis (is_marker_for)	LRRK2 CCR3 MMP9	1.02e-03	69	84	3	DOID:7148 (is_marker_for)
Disease	p-tau measurement	UNC5C MTBP UPP2	1.15e-03	72	84	3	EFO_0004763
Disease	angiopoietin-related protein 1 measurement	UGT1A8 APOH	1.19e-03	18	84	2	EFO_0801382
Disease	esophagus squamous cell carcinoma (is_marker_for)	CXCR4 MMP9 SLC16A10	1.25e-03	74	84	3	DOID:3748 (is_marker_for)
Disease	bilirubin measurement	SLC22A18 FAM234A UGT1A8 TRPM8 MEAK7 PHIP	1.66e-03	442	84	6	EFO_0004570
Disease	systemic scleroderma	IL12RB1 IL12RB2 MMP9	1.86e-03	85	84	3	EFO_0000717
Disease	vasculitis	IL12RB2 CCR3	2.12e-03	24	84	2	EFO_0006803
Disease	systemic mastocytosis	EYS OR51Q1	2.30e-03	25	84	2	MONDO_0016586
Disease	colon adenocarcinoma (is_marker_for)	SLC22A18 MMP9	2.30e-03	25	84	2	DOID:234 (is_marker_for)
Disease	retinitis pigmentosa (implicated_via_orthology)	SLC6A6 EYS	2.68e-03	27	84	2	DOID:10584 (implicated_via_orthology)
Disease	S-warfarin measurement	SLC6A6 GPR37 ABCC11	2.71e-03	97	84	3	EFO_0803323
Disease	reaction time measurement	NFIX PLA2G3 LRRK2 CD47 PITPNM3 MFSD2B MMP9	2.73e-03	658	84	7	EFO_0008393

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTLCPLCFSILKGPI	ADNP	621	Q9H2P0
ILFPCASSLCGCSVK	FAM234A	276	Q9H0X4
SCGCILGELFTKKPI	CDK12	921	Q9NYV4
TLKCTPRVCPFAGIL	APOH	76	P02749
PGIVILSCYCIIISK	CXCR4	211	P61073
ICPALAVGCTVVALV	ALDH16A1	186	Q8IZ83
LGGLPLLITTCFCLF	BTLA	161	Q7Z6A9
CPICKGLFTAINLGL	SMPD1	91	P17405
AVGEPLYTCATLCLK	ADGRV1	2431	Q8WXG9
AVSVPFLLLCVLGTC	ADAM22	6	Q9P0K1
LGKTGIKTSCLCPVF	HSD17B13	206	Q7Z5P4
PLGVSTELIGLCICF	CCDC163	31	A0A0D9SF12
FVLTVTGKKPPCCVL	NFIA	91	Q12857
ICFCLLGITCAIPVK	SPP1	6	P10451
LVDLLCCGAILFPVV	GPR107	406	Q5VW38
IPESVTCACLKIFLS	NOL11	496	Q9H8H0
PLVLVLLVLGCCFAA	MMP9	6	P14780
YLVSLGCIKPLCDLL	KPNA6	416	O60684
ACVFILVGPLCLVLV	OR2A14	201	Q96R47
ICEVPVLIKLACVGT	OR2G2	181	Q8NGZ5
FVLTITGKKPPCCVL	NFIX	91	Q14938
CICSPIFTDLLCKSI	EYS	356	Q5T1H1
ETCLPLIGFILICLK	FNDC7	6	Q5VTL7
GLPLGTTLFVCKLAC	IL12RB2	91	Q99665
LGIPVLVVCTKCDAI	DYNC1LI1	236	Q9Y6G9
IICAPTGCGKTFVSL	DDX58	261	O95786
ALLSTTGFDCPCILL	OR51F2	216	Q8NH61
TGLAIICCCVLAVLP	OR51Q1	146	Q8NH59
ICFCIASVLGPILII	ABCC11	171	Q96J66
CYGPLVLITCASLVI	ABCC11	276	Q96J66
SFLKITVPSCRKGCI	LRRK2	1761	Q5S007
TYPVCISLLCLGVKE	MFSD2B	241	A6NFX1
SVKLCDCPGLIFPSL	GNL1	406	P36915
SVVICKGFLILCSSL	MEAK7	211	Q6P9B6
TLVLGFVLPVCTICV	NPBWR2	216	P48146
MAPKLITVLCLGFCL	KIR3DX1	1	Q9H7L2
PLLTFSKFCCTVLLQ	FANCB	586	Q8NB91
CLVPTFAVSCLLLGL	NPC1L1	1146	Q9UHC9
LLCCLVGTLPLAIFF	ADCY1	731	Q08828
YKCDAVLCTLPLGVL	KDM1A	616	O60341
KSCVTPVLLFCLCKP	GPR37	541	O15354
AICYTGIIKTLLRCP	CCR3	216	P51677
FFKGAITPVLLLCIC	GPR37L1	406	O60883
LSTCPGVLKEYVVRC	IL12RB1	471	P42701
PSCGYVLCTVLLALA	FIBCD1	26	Q8N539
CSTITLCLVFVPKLI	GABBR2	731	O75899
TLTCKVIAFLGVLSC	GPR85	91	P60893
LAVVGLSLCIAACIP	CD47	251	Q08722
VLVGVVCLLLACPAT	CES3	11	Q6UWW8
ICLAVPTVLCGTVFC	HSD17B2	11	P37059
LAGLCAVCLLILSPF	HSD17B2	41	P37059
GILSALPFVVGCICI	SLC17A4	331	Q9Y2C5
LPLGCITILFIELCT	ATP4A	811	P20648
KAGPSIVICFLVAAL	SLC7A3	61	Q8WY07
IISCIGCFGLFSKIL	DENND2D	156	Q9H6A0
LCSKVGALFVLPCTI	MTBP	346	Q96DY7
SKRLCCALVTGPYVI	OR8H1	136	Q8NGG4
ICGVLVLVVPFLFIC	OR10R2	221	Q8NGX6
LCGLKAAVVCVTLLD	UPP2	266	O95045
SFMGALSVVLPCLLC	SPRY4	236	Q9C004
ITPVLCVGCFIFSLV	SLC6A6	511	P31641
GVVPCCTSLEKLLLY	FBXL18	186	Q96ME1
PLFCSVLTKLGCGLL	PITRM1	616	Q5JRX3
LAKPVLCLGTLCTAF	PLPPR1	226	Q8TBJ4
LGTTCFKLAPPLDCV	PLA2G3	421	Q9NZ20
FCLLVPGLVFSLCTL	SLC22A18	331	Q96BI1
PVIKAFLCGSISGTC	SLC25A38	26	Q96DW6
KEALTGLVCLVCFLS	SLC6A18	441	Q96N87
LALTLGCGLTPICFK	SLC39A2	16	Q9NP94
IPGVLCLCVSFKNIV	SH2D1B	36	O14796
KFCLFCTVVSLLGIL	SLCO4A1	456	Q96BD0
PLLLLILVAFGTCCF	CHODL	226	Q9H9P2
LVVGCLLPFFTLSIC	CYSLTR2	206	Q9NS75
PGKFCLLSCGILTFL	RETREG3	166	Q86VR2
TKIGLCLFSLACVPF	SLC49A3	316	Q6UXD7
LGIFSCLCLPELLKV	SKP2	106	Q13309
CAVLGLCLAVPDKTV	TF	11	P02787
IVGIKYEVGLPTLCC	PHIP	1006	Q8WWQ0
VAFSTCVIKVPLGRC	SEMA6A	501	Q9H2E6
FCGLISFLSIAPCIR	SERINC4	266	A6NH21
ILIKFVPCPAICSEA	PITPNM3	176	Q9BZ71
LGVLSCLGFVVLKLC	TMEM187	196	Q14656
GVLLLVLALCCKVGF	SLC30A5	206	Q8TAD4
ILCLFIIPLVGCGFV	TRPM8	696	Q7Z2W7
KCPIFLGCIICVTGL	TOPBP1	196	Q92547
RLKLAIFGPLCCSSL	UNC5C	681	O95185
SLVLAPALAACGCKV	TYMP	126	P19971
EKPLLLLCCASFLLG	TMEM139	11	Q8IV31
FSVGLTVCKPGLITC	ZNF195	41	O14628
PLCVSLLLTCGFAEA	UGT1A8	11	Q9HAW9
IPLCSIFGALIAVCL	SLC16A10	376	Q8TF71