Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	myofibril	BIN1 NRAP STYXL2 CMYA5 SVIL SYNE2 DMD MYBPC1	9.29e-05	273	109	8	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	BIN1 NRAP STYXL2 CMYA5 SVIL SYNE2 DMD MYBPC1	1.41e-04	290	109	8	GO:0043292
GeneOntologyCellularComponent	costamere	CMYA5 SVIL DMD	1.98e-04	22	109	3	GO:0043034
GeneOntologyCellularComponent	sarcomere	BIN1 NRAP STYXL2 CMYA5 SYNE2 DMD MYBPC1	3.32e-04	249	109	7	GO:0030017
GeneOntologyCellularComponent	supramolecular fiber	BIN1 NRAP REEP1 STYXL2 EVPL CMYA5 SHANK2 SVIL SYNE2 DIAPH1 MACF1 TNK2 DMD DNAH8 DYNC1H1 MYBPC1	3.98e-04	1179	109	16	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	BIN1 NRAP REEP1 STYXL2 EVPL CMYA5 SHANK2 SVIL SYNE2 DIAPH1 MACF1 TNK2 DMD DNAH8 DYNC1H1 MYBPC1	4.28e-04	1187	109	16	GO:0099081
GeneOntologyCellularComponent	anchoring junction	FLT1 NRAP ARHGAP26 EVPL UBOX5 TENM2 ITK PKP3 SVIL SYNE2 LRP1 TNK2 DMD ARHGAP21	5.49e-04	976	109	14	GO:0070161
GeneOntologyCellularComponent	presynapse	AMPH BIN1 SNX4 SEMA7A NTF3 SHANK2 TENM3 SV2B CPLX3 DIAPH1 RNF216 TNK2 DMD	7.11e-04	886	109	13	GO:0098793
GeneOntologyCellularComponent	axon	AMPH BIN1 NTF3 USP9X PLXND1 TENM2 SHANK2 TENM3 CPLX3 LRP1 TNK2 DMD DYNC1H1	7.49e-04	891	109	13	GO:0030424
GeneOntologyCellularComponent	leading edge membrane	AMPH PLXND1 SHISA9 SYNE2 DIAPH1 MACF1	8.21e-04	210	109	6	GO:0031256
GeneOntologyCellularComponent	actin cytoskeleton	DENND2A FLT1 AMPH BIN1 MYO5C SVIL DIAPH1 MACF1 PLEKHH2 ARHGAP21	8.65e-04	576	109	10	GO:0015629
GeneOntologyCellularComponent	glutamatergic synapse	AMPH BIN1 WNT5A PLXND1 TENM2 SHISA9 SHANK2 TENM3 SV2B LRP1 RNF216 PLAT	1.14e-03	817	109	12	GO:0098978
GeneOntologyCellularComponent	cell projection membrane	PLXND1 ADCY3 SHISA9 SHANK2 SYNE2 DIAPH1 MACF1 DMD	1.90e-03	431	109	8	GO:0031253
GeneOntologyCellularComponent	distal axon	AMPH BIN1 USP9X TENM2 SHANK2 CPLX3 LRP1 TNK2	2.01e-03	435	109	8	GO:0150034
GeneOntologyCellularComponent	cell-substrate junction	FLT1 NRAP ARHGAP26 UBOX5 SVIL SYNE2 LRP1 DMD	2.25e-03	443	109	8	GO:0030055
GeneOntologyCellularComponent	neurofilament	SHANK2 DMD	2.35e-03	14	109	2	GO:0005883
GeneOntologyCellularComponent	postsynapse	BIN1 USP9X WNT5A TENM2 CHRNA2 SHISA9 SHANK2 LRP1 MACF1 RNF216 TNK2 PLAT DMD	2.47e-03	1018	109	13	GO:0098794
GeneOntologyCellularComponent	exocytic vesicle membrane	AMPH BIN1 SV2B CPLX3 DMD	2.48e-03	179	109	5	GO:0099501
GeneOntologyCellularComponent	synaptic vesicle membrane	AMPH BIN1 SV2B CPLX3 DMD	2.48e-03	179	109	5	GO:0030672
Domain	Tox-GHH_dom	TENM2 TENM3 TENM1	7.49e-07	4	108	3	IPR028916
Domain	Tox-GHH	TENM2 TENM3 TENM1	7.49e-07	4	108	3	PF15636
Domain	Ten_N	TENM2 TENM3 TENM1	7.49e-07	4	108	3	IPR009471
Domain	Ten_N	TENM2 TENM3 TENM1	7.49e-07	4	108	3	PF06484
Domain	TENEURIN_N	TENM2 TENM3 TENM1	7.49e-07	4	108	3	PS51361
Domain	YD	TENM2 TENM3 TENM1	1.86e-06	5	108	3	IPR006530
Domain	Spectrin_repeat	EVPL SYNE2 MACF1 DMD	2.25e-05	29	108	4	IPR002017
Domain	SPEC	EVPL SYNE2 MACF1 DMD	3.36e-05	32	108	4	SM00150
Domain	Spectrin/alpha-actinin	EVPL SYNE2 MACF1 DMD	3.36e-05	32	108	4	IPR018159
Domain	SH3	AMPH BIN1 ARHGAP26 ITK SHANK2 MACF1 TNK2 SKAP2	3.67e-05	216	108	8	PS50002
Domain	SH3_domain	AMPH BIN1 ARHGAP26 ITK SHANK2 MACF1 TNK2 SKAP2	4.18e-05	220	108	8	IPR001452
Domain	NHL	TENM2 TENM3 TENM1	5.16e-05	13	108	3	PS51125
Domain	-	TENM2 TENM3 TENM1 LRP1	7.44e-05	39	108	4	2.120.10.30
Domain	Rhs_assc_core	TENM2 TENM3	9.90e-05	3	108	2	IPR022385
Domain	Qua1_dom	KHDRBS2 KHDRBS3	9.90e-05	3	108	2	IPR032571
Domain	Sam68-YY	KHDRBS2 KHDRBS3	9.90e-05	3	108	2	IPR032335
Domain	Amphiphysin	AMPH BIN1	9.90e-05	3	108	2	IPR003005
Domain	Sam68-YY	KHDRBS2 KHDRBS3	9.90e-05	3	108	2	PF16568
Domain	Qua1	KHDRBS2 KHDRBS3	9.90e-05	3	108	2	PF16274
Domain	6-blade_b-propeller_TolB-like	TENM2 TENM3 TENM1 LRP1	1.43e-04	46	108	4	IPR011042
Domain	SH3	AMPH BIN1 ARHGAP26 ITK SHANK2 TNK2 SKAP2	2.61e-04	216	108	7	SM00326
Domain	Spectrin	SYNE2 MACF1 DMD	3.06e-04	23	108	3	PF00435
Domain	ACTININ_2	SYNE2 MACF1 DMD	3.06e-04	23	108	3	PS00020
Domain	ACTININ_1	SYNE2 MACF1 DMD	3.06e-04	23	108	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE2 MACF1 DMD	3.06e-04	23	108	3	IPR001589
Domain	SH3_1	AMPH BIN1 ARHGAP26 ITK TNK2 SKAP2	3.82e-04	164	108	6	PF00018
Domain	-	EVPL MACF1	4.89e-04	6	108	2	3.90.1290.10
Domain	Plectin	EVPL MACF1	6.83e-04	7	108	2	PF00681
Domain	Plectin_repeat	EVPL MACF1	6.83e-04	7	108	2	IPR001101
Domain	PLEC	EVPL MACF1	6.83e-04	7	108	2	SM00250
Domain	DHC_N1	DNAH8 DYNC1H1	9.07e-04	8	108	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH8 DYNC1H1	9.07e-04	8	108	2	IPR013594
Domain	EGF	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	2.45e-03	235	108	6	SM00181
Domain	EGF_3	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	2.45e-03	235	108	6	PS50026
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DYNC1H1	2.88e-03	14	108	2	IPR024317
Domain	Dynein_HC_stalk	DNAH8 DYNC1H1	2.88e-03	14	108	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH8 DYNC1H1	2.88e-03	14	108	2	IPR013602
Domain	DHC_N2	DNAH8 DYNC1H1	2.88e-03	14	108	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH8 DYNC1H1	2.88e-03	14	108	2	IPR011704
Domain	MT	DNAH8 DYNC1H1	2.88e-03	14	108	2	PF12777
Domain	AAA_8	DNAH8 DYNC1H1	2.88e-03	14	108	2	PF12780
Domain	AAA_5	DNAH8 DYNC1H1	2.88e-03	14	108	2	PF07728
Domain	EGF-like_dom	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	3.26e-03	249	108	6	IPR000742
Domain	DHC_fam	DNAH8 DYNC1H1	3.31e-03	15	108	2	IPR026983
Domain	BAR	AMPH BIN1	3.31e-03	15	108	2	SM00721
Domain	Dynein_heavy	DNAH8 DYNC1H1	3.31e-03	15	108	2	PF03028
Domain	BAR	AMPH BIN1	3.31e-03	15	108	2	PF03114
Domain	Dynein_heavy_dom	DNAH8 DYNC1H1	3.31e-03	15	108	2	IPR004273
Domain	EGF_1	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	3.67e-03	255	108	6	PS00022
Domain	BAR_dom	AMPH BIN1	3.77e-03	16	108	2	IPR004148
Domain	EGF-like_CS	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	4.10e-03	261	108	6	IPR013032
Domain	CarboxyPept-like_regulatory	TENM2 TENM3	4.26e-03	17	108	2	IPR008969
Domain	EGF_2	TENM2 TENM3 TLL2 TENM1 LRP1 PLAT	4.42e-03	265	108	6	PS01186
Domain	BAR	AMPH BIN1	5.31e-03	19	108	2	PS51021
Domain	PH	IRS4 ARHGAP26 ITK PLEKHH2 SKAP2 ARHGAP21	5.56e-03	278	108	6	SM00233
Domain	PH_DOMAIN	IRS4 ARHGAP26 ITK PLEKHH2 SKAP2 ARHGAP21	5.66e-03	279	108	6	PS50003
Domain	PH_domain	IRS4 ARHGAP26 ITK PLEKHH2 SKAP2 ARHGAP21	5.76e-03	280	108	6	IPR001849
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	AMPH BIN1 SNX4 KHDRBS2 ZFC3H1 KHDRBS3 MACF1 DMD DYNC1H1	1.92e-10	120	111	9	31413325
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	NUP85 MCM4 PRPF8 YEATS4 SLC25A13 SYNE2 ALB DMD PLEKHH2 TASOR TXLNG ZRANB1 ARHGAP21 DYNC1H1 MAP3K19	1.90e-08	754	111	15	35906200
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT172 PEG3 TENM2 ADCY3 TENM3 SETD5 SV2B TLE3 MACF1 ARHGAP21 DYNC1H1	8.18e-08	407	111	11	12693553
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM2 TENM3 TENM1	1.26e-07	4	111	3	10225957
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM2 TENM3 TENM1	1.26e-07	4	111	3	12000766
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BIN1 ZRSR2 USP9X IFT172 PEG3 ZFC3H1 CMYA5 PRPF8 LRP1 MACF1 RNF216 MIGA1 ZNF606 DNAJB2 TXLNG ARHGAP21 TARS1 DYNC1H1	1.35e-07	1285	111	18	35914814
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IRS4 NUP85 BCLAF1 KHDRBS2 ZFC3H1 PRPF8 SHANK2 KHDRBS3 SETD5 SLC25A13 SYNE2 TENM1 MACF1 DMD SKAP2 TASOR DNAH8 ARHGAP21 MYBPC1	1.49e-07	1442	111	19	35575683
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	IRS4 NUP85 BCLAF1 USP9X MCM4 PRPF8 MYO5C PKP3 SLC25A13 SVIL SYNE2 MACF1 ALYREF ALB TARS1 DYNC1H1	1.69e-07	1024	111	16	24711643
Pubmed	Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton.	AMPH BIN1 SYNE2	3.15e-07	5	111	3	26506308
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM2 TENM3 TENM1	1.10e-06	7	111	3	12915301
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NTF3 TTC14 ADCY3 HPS3 SBNO2 SHISA9 TMCO4 STK10 SHANK2 SETD5 TLE3 PKP3 LRP1 MACF1 TNK2 ZRANB1 CRAMP1 TRAPPC9	1.14e-06	1489	111	18	28611215
Pubmed	Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.	TENM2 TENM3 TENM1	1.75e-06	8	111	3	10331952
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NUP85 SEMA7A ARHGAP26 PLXND1 SBNO2 STK10 SHANK2 SETD5 TNK2 DOT1L MMP17 ARHGAP21 CRAMP1 TRAPPC9 DYNC1H1	2.43e-06	1105	111	15	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DENND2A AMPH BIN1 BCLAF1 USP9X ARHGAP26 SHANK2 SV2B SVIL MACF1 ALB DMD ARHGAP21 TARS1 TRAPPC9 DYNC1H1 PTCD3	2.96e-06	1431	111	17	37142655
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	PEG3 CHGB REST SHANK2 MACF1 ARHGAP21	3.65e-06	128	111	6	30995482
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM2 TENM3 TENM1	3.74e-06	10	111	3	38713721
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KANSL1L BIN1 NRAP PEG3 CMYA5 SYNE2 MACF1 SKAP2 ARHGAP21 MYBPC1	4.61e-06	497	111	10	23414517
Pubmed	Systematic Identification of Oncogenic EGFR Interaction Partners.	AMPH DIAPH1 SKAP2	6.82e-06	12	111	3	27956147
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ARHGAP26 PEG3 TTC14 ZNF429 UBOX5 ADCY3 SBNO2 SETD5 HPS1 DIAPH1 MACF1 DOT1L TASOR ARHGAP21	9.52e-06	1084	111	14	11544199
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	IRS4 ADCY3 RGS12 TENM3 SYNE2 MACF1 DMD DYNC1H1	9.56e-06	322	111	8	26514267
Pubmed	DNAJB2 expression in normal and diseased human and mouse skeletal muscle.	DMD DNAJB2	1.01e-05	2	111	2	20395441
Pubmed	The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.	LRP1 PLAT	1.01e-05	2	111	2	18321860
Pubmed	Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins.	KHDRBS2 KHDRBS3	1.01e-05	2	111	2	25505328
Pubmed	Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation.	LRP1 PLAT	1.01e-05	2	111	2	10632583
Pubmed	Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking.	BIN1 SNX4	1.01e-05	2	111	2	12668730
Pubmed	GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice.	ARHGAP26 DMD	1.01e-05	2	111	2	26301073
Pubmed	Mutation analysis of patients with Hermansky-Pudlak syndrome: a frameshift hot spot in the HPS gene and apparent locus heterogeneity.	HPS3 HPS1	1.01e-05	2	111	2	9497254
Pubmed	Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.	LRP1 PLAT	1.01e-05	2	111	2	1502153
Pubmed	Recombinant Tissue Plasminogen Activator (r-tPA) Induces In-Vitro Human Neutrophil Migration via Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1).	LRP1 PLAT	1.01e-05	2	111	2	32977685
Pubmed	Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1.	LRP1 PLAT	1.01e-05	2	111	2	26237273
Pubmed	Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle.	AMPH BIN1	1.01e-05	2	111	2	9182667
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	USP9X MCM4 PRPF8 SETD5 BRPF1 SVIL MACF1 DYNC1H1	1.19e-05	332	111	8	37433992
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	BIN1 BCLAF1 USP9X TENM2 SHANK2 SVIL SYNE2 DIAPH1 LRP1 MACF1 ALYREF ARHGAP21 DYNC1H1	1.28e-05	963	111	13	28671696
Pubmed	Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.	AMPH BIN1 TNK2	1.40e-05	15	111	3	19144635
Pubmed	Dual role of Fam208a during zygotic cleavage and early embryonic development.	SVIL ALB TASOR	1.72e-05	16	111	3	34216590
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	BCLAF1 WNT5A MCM4 PRPF8 TENM3 SYNE2 MACF1 DYNC1H1	2.05e-05	358	111	8	32460013
Pubmed	Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.	TENM2 TENM3 TENM1 DYNC1H1	2.19e-05	51	111	4	16919471
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	BIN1 IRS4 USP9X MCM4 SYNE2 POC1B DNAJB2 TXLNG	2.26e-05	363	111	8	25036637
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	IRS4 WNT5A SVIL TENM1 SECISBP2 MACF1 ARHGAP21	2.27e-05	263	111	7	34702444
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	IRS4 USP9X MCM4 PRPF8 SLC25A13 TARS1	2.47e-05	179	111	6	36261009
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	IRS4 USP9X PRPF8 SLC25A13 ZNF282 DYNC1H1 PTCD3	2.81e-05	272	111	7	25315684
Pubmed	Disorders of vesicles of lysosomal lineage: the Hermansky-Pudlak syndromes.	HPS3 HPS1	3.02e-05	3	111	2	12125811
Pubmed	Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein.	LRP1 PLAT	3.02e-05	3	111	2	19608750
Pubmed	Tissue-type plasminogen activator regulates macrophage activation and innate immunity.	LRP1 PLAT	3.02e-05	3	111	2	28684538
Pubmed	Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain.	LRP1 PLAT	3.02e-05	3	111	2	19672275
Pubmed	NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients.	HPS3 HPS1	3.02e-05	3	111	2	27593200
Pubmed	Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites.	AMPH BIN1	3.02e-05	3	111	2	9603201
Pubmed	Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.	AMPH BIN1	3.02e-05	3	111	2	23399914
Pubmed	Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.	AMPH BIN1	3.02e-05	3	111	2	9736607
Pubmed	Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathway.	LRP1 PLAT	3.02e-05	3	111	2	25670857
Pubmed	SH3 domain-dependent interactions of endophilin with amphiphysin.	AMPH BIN1	3.02e-05	3	111	2	9315708
Pubmed	LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling.	WNT5A LRP1	3.02e-05	3	111	2	18990694
Pubmed	Amphiphysin IIb-1, a novel splicing variant of amphiphysin II, regulates p73beta function through protein-protein interactions.	AMPH BIN1	3.02e-05	3	111	2	11709703
Pubmed	Wnt5a-Flt1 activation contributes to preterm altered cerebral angiogenesis after prenatal inflammation.	FLT1 WNT5A	3.02e-05	3	111	2	36922327
Pubmed	Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.	LRP1 PLAT	3.02e-05	3	111	2	17170123
Pubmed	Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression.	LRP1 PLAT	3.02e-05	3	111	2	16303771
Pubmed	LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.	LRP1 PLAT	3.02e-05	3	111	2	24129569
Pubmed	A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation.	RGS12 DMD	3.02e-05	3	111	2	31408461
Pubmed	SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3' UTR Isoforms in the Nervous System.	KHDRBS2 KHDRBS3	3.02e-05	3	111	2	31805436
Pubmed	Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis.	AMPH BIN1	3.02e-05	3	111	2	9348539
Pubmed	Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy.	FLT1 DMD	3.02e-05	3	111	2	31877123
Pubmed	Inhibition of HIV-1 gene expression by Sam68 Delta C: multiple targets but a common mechanism?	KHDRBS2 KHDRBS3	3.02e-05	3	111	2	19254361
Pubmed	Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.	SVIL DMD	3.02e-05	3	111	2	12711699
Pubmed	Mapping of determinants involved in the stimulation of HIV-1 expression by Sam68.	KHDRBS2 KHDRBS3	3.02e-05	3	111	2	19091369
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	BCLAF1 ZFC3H1 TENM3 SYNE2 DMD DNAH8	3.16e-05	187	111	6	26460568
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	IFT172 TTC14 MACF1	3.47e-05	20	111	3	21689717
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	BCLAF1 PEG3 ZNF429 STK10 ALYREF ALB DYNC1H1	3.70e-05	284	111	7	29459677
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	IRS4 NUP85 USP9X IFT172 MCM4 PRPF8 SLC25A13 DIAPH1 TARS1 DYNC1H1	3.94e-05	638	111	10	33239621
Pubmed	Agrin has a pathological role in the progression of oral cancer.	IRS4 REST PRPF8 TENM3 DMD MYBPC1	4.23e-05	197	111	6	29872149
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	IRS4 USP9X SYNE2 MACF1 PLAT DMD	4.23e-05	197	111	6	20811636
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IRS4 USP9X MCM4 PRPF8 SLC25A13 SYNE2 MACF1 ALYREF DYNC1H1 PTCD3	4.78e-05	653	111	10	22586326
Pubmed	Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.	IRS4 USP9X MYO5C SLC25A13 SVIL	5.23e-05	125	111	5	36030824
Pubmed	KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.	FLT1 PLXND1 KLF13	5.35e-05	23	111	3	28164238
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	BCLAF1 USP9X MCM4 PRPF8 DIAPH1 MACF1 DMD TARS1 DYNC1H1	5.93e-05	538	111	9	28524877
Pubmed	Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes.	HPS3 HPS1	6.03e-05	4	111	2	29190429
Pubmed	Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma.	SNRNP25 LRP1	6.03e-05	4	111	2	25300797
Pubmed	Genetic testing for oculocutaneous albinism type 1 and 2 and Hermansky-Pudlak syndrome type 1 and 3 mutations in Puerto Rico.	HPS3 HPS1	6.03e-05	4	111	2	16417222
Pubmed	The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.	KHDRBS2 KHDRBS3	6.03e-05	4	111	2	15471878
Pubmed	Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4.	HPS3 HPS1	6.03e-05	4	111	2	12847290
Pubmed	Inhibition of phospholipase D by amphiphysins.	AMPH BIN1	6.03e-05	4	111	2	10764771
Pubmed	Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy.	CMYA5 DMD	6.03e-05	4	111	2	18252718
Pubmed	Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair.	FLT1 WNT5A	6.03e-05	4	111	2	23303818
Pubmed	SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.	KHDRBS2 KHDRBS3	6.03e-05	4	111	2	22196734
Pubmed	Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle.	SVIL DMD	6.03e-05	4	111	2	25605665
Pubmed	The microRNA/TET3/REST axis is required for olfactory globose basal cell proliferation and male behavior.	REST ADCY3	6.03e-05	4	111	2	32677323
Pubmed	Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.	LRP1 PLAT	6.03e-05	4	111	2	18037995
Pubmed	The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.	HPS3 HPS1	6.03e-05	4	111	2	23043085
Pubmed	Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation.	TLE3 ALB	6.03e-05	4	111	2	20108349
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	MACF1 DMD	6.03e-05	4	111	2	8954775
Pubmed	The PDGF family: four gene products form five dimeric isoforms.	PDGFD PLAT	6.03e-05	4	111	2	15207811
Pubmed	Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome.	HPS3 HPS1	6.03e-05	4	111	2	17365864
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	DNAH8 DYNC1H1	6.03e-05	4	111	2	15762842
Pubmed	Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.	LRP1 PLAT	6.03e-05	4	111	2	14617754
Pubmed	Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription.	NAB1 DMD	6.03e-05	4	111	2	7624335
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	DENND2A SVIL TNK2 ARHGAP21	6.45e-05	67	111	4	29254152
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	NUP85 IFT172 ARHGAP26 MCM4 EVPL PRPF8 PKP3 LRP1 ALYREF BZW1 DMD PTCD3	6.76e-05	974	111	12	28675297
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	IRS4 BCLAF1 USP9X PRPF8 KHDRBS3 ALYREF ALB TASOR PTCD3	7.12e-05	551	111	9	34728620
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	MCM4 CHGB TENM2	7.80e-05	26	111	3	15890332
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	IRS4 NUP85 MCM4 PRPF8 SLC25A13 DIAPH1 BZW1 DYNC1H1 PTCD3	8.05e-05	560	111	9	35241646
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	BCLAF1 PKP3 SLC25A13 SVIL ALYREF ALB	8.40e-05	223	111	6	33731348
Interaction	SPAST interactions	AMPH BIN1 NUP85 SHANK2 SVIL ALB ZRANB1	8.63e-06	136	108	7	int:SPAST
Interaction	SRGAP2 interactions	ARHGAP26 SYNE2 DIAPH1 TNK2 DOT1L ZRANB1 ARHGAP21 TARS1	1.10e-05	197	108	8	int:SRGAP2
Interaction	PRICKLE1 interactions	USP9X ARHGAP26 SYNE2 DMD ARHGAP21	1.74e-05	60	108	5	int:PRICKLE1
Interaction	LUC7L2 interactions	ZRSR2 BCLAF1 PRPF8 SVIL ALB BZW1 DOT1L ZRANB1 DYNC1H1 PTCD3	2.03e-05	353	108	10	int:LUC7L2
Interaction	PRICKLE2 interactions	USP9X ARHGAP26 SYNE2 DMD ARHGAP21	2.04e-05	62	108	5	int:PRICKLE2
Interaction	LHX5 interactions	ARHGAP26 SYNE2 DMD	2.39e-05	11	108	3	int:LHX5
Interaction	SRSF2 interactions	THNSL1 ZRSR2 PRPF8 POC1B ALYREF BZW1 DOT1L ZRANB1 DYNC1H1	2.63e-05	290	108	9	int:SRSF2
Interaction	THOC7 interactions	BCLAF1 ARHGAP26 TLE3 ALYREF ZNF606 ZRANB1	3.44e-05	114	108	6	int:THOC7
Interaction	MKRN2 interactions	BCLAF1 WNT5A ZFC3H1 TENM3 SYNE2 SECISBP2 MACF1 ALYREF PLEKHH2 DYNC1H1	4.23e-05	385	108	10	int:MKRN2
Interaction	SNRPA interactions	BCLAF1 ZFC3H1 PRPF8 KHDRBS3 POLR3E ALYREF BZW1 TASOR ZRANB1 DYNC1H1 PTCD3	5.59e-05	482	108	11	int:SNRPA
Interaction	BIN1 interactions	AMPH BIN1 SNX4 IRS4 SYNE2 TNK2	6.87e-05	129	108	6	int:BIN1
Interaction	SNRNP35 interactions	SNRNP25 ZRSR2 PRPF8 ZRANB1	8.19e-05	43	108	4	int:SNRNP35
Interaction	PEG3 interactions	PEG3 ALB ZRANB1	9.64e-05	17	108	3	int:PEG3
Interaction	SNRPB interactions	SNRNP25 ZRSR2 BCLAF1 USP9X PRPF8 MACF1 ALYREF SKAP2 TASOR DYNC1H1 PTCD3	1.04e-04	517	108	11	int:SNRPB
Interaction	SF3B2 interactions	ZRSR2 NOL12 TTC14 MCM4 REST PRPF8 BZW1 DMD DOT1L ZRANB1 DYNC1H1	1.04e-04	517	108	11	int:SF3B2
Interaction	THOC6 interactions	BCLAF1 ARHGAP26 ALYREF DOT1L ZRANB1	1.05e-04	87	108	5	int:THOC6
Interaction	SRRM1 interactions	BCLAF1 USP9X PRPF8 SYNE2 ALYREF BZW1 DOT1L ZRANB1 DYNC1H1	1.07e-04	348	108	9	int:SRRM1
Interaction	DMD interactions	ARHGAP26 REST SYNE2 ALB DMD ZRANB1	1.12e-04	141	108	6	int:DMD
Interaction	PSD4 interactions	THNSL1 USP9X ZRANB1	1.15e-04	18	108	3	int:PSD4
Interaction	MYCBP2 interactions	BCLAF1 WNT5A RGS12 SVIL SYNE2 MACF1 ZRANB1 ARHGAP21 DYNC1H1	1.25e-04	355	108	9	int:MYCBP2
Interaction	LYN interactions	IRS4 KHDRBS2 PRPF8 ADCY3 STK10 YEATS4 SVIL MACF1 TNK2 DMD PLEKHH2 SKAP2 ARHGAP21	1.26e-04	720	108	13	int:LYN
Interaction	FMR1 interactions	BIN1 BCLAF1 USP9X WNT5A LRP1 SECISBP2 MACF1 DOT1L ZRANB1 ARHGAP21 DYNC1H1	1.43e-04	536	108	11	int:FMR1
Interaction	MLLT10 interactions	YEATS4 TLE3 DOT1L ZRANB1	1.61e-04	51	108	4	int:MLLT10
Interaction	RBBP6 interactions	BCLAF1 PRPF8 RGS12 KHDRBS3 TLE3 DOT1L ZRANB1	1.64e-04	216	108	7	int:RBBP6
Interaction	FOXA3 interactions	KHDRBS2 MCM4 TLE3 ALB	1.73e-04	52	108	4	int:FOXA3
GeneFamily	Signal transduction and activation of RNA metabolism family	KHDRBS2 KHDRBS3	5.08e-05	3	75	2	1275
GeneFamily	EF-hand domain containing\|Plakins	EVPL MACF1	4.68e-04	8	75	2	939
GeneFamily	N-BAR domain containing	AMPH BIN1	1.09e-03	12	75	2	1289
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	BIN1 BCLAF1 USP9X TTC14 REST ZFC3H1 PRPF8 ITK SBNO2 STK10 KLF13 SETD5 DIAPH1 SECISBP2 MACF1 RNF216 TNK2 BZW1 TASOR DYNC1H1	3.12e-06	1492	109	20	M40023
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AMPH KHDRBS2 CHGB TENM2 CHRNA2 RGS12 SHANK2 CPLX3	3.43e-08	200	109	8	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AMPH KHDRBS2 CHGB TENM2 CHRNA2 RGS12 SHANK2 CPLX3	3.43e-08	200	109	8	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AMPH KHDRBS2 CHGB TENM2 CHRNA2 RGS12 SHANK2 CPLX3	3.43e-08	200	109	8	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KHDRBS2 CMYA5 RFX8 TENM2 KHDRBS3 SV2B PLEKHH2	3.58e-07	184	109	7	6475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AMPH WNT5A FAM135B PDGFD PLAT DMD PLEKHH2	4.14e-07	188	109	7	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 DMD PLEKHH2	5.11e-07	194	109	7	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM3 POLR3E TLE3 PCDH15 PLEKHH2 MYBPC1	2.56e-06	158	109	6	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH ADCY3 LRP1 DMD PLEKHH2 MMP17	3.91e-06	170	109	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHGB STK10 TLE3 SYNE2 LRP1 MMP17	4.62e-06	175	109	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PEG3 CMYA5 MACF1 DMD TASOR ARHGAP21	4.77e-06	176	109	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	wk_08-11-Epithelial-PNS-Late_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FAM135B SHISA9 KHDRBS3 TENM3 SV2B MMP17	5.09e-06	178	109	6	a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DENND2A WNT5A CHRNA2 RGS12 ZFHX4 PLAT	5.78e-06	182	109	6	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP CMYA5 TENM2 SVIL RNF216 DMD	5.78e-06	182	109	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	ARHGAP26 STK10 PDGFD SYNE2 DIAPH1 MACF1	5.97e-06	183	109	6	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	BCLAF1 USP9X ARHGAP26 SYNE2 MACF1 DYNC1H1	6.96e-06	188	109	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.18e-06	189	109	6	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.18e-06	189	109	6	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP CMYA5 TENM2 SVIL DIAPH1 DMD	7.18e-06	189	109	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	P07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 BIN1 REEP1 SEMA7A RGS12 PDGFD	7.40e-06	190	109	6	5d25e40bc2cca314f4265e4001a546e6d99e2a79
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	NRAP CMYA5 TENM2 SVIL DIAPH1 DMD	7.40e-06	190	109	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.40e-06	190	109	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A PEG3 PDGFD PCDH15 LRP1 PLEKHH2	7.40e-06	190	109	6	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.62e-06	191	109	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TENM2 MYO5C TMCO4 SHANK2 PKP3 DMD	7.62e-06	191	109	6	05731ece7867659c662f952812805f947032fe10
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTF3 ADCY3 ZFHX4 TENM3 LRP1 DMD	7.85e-06	192	109	6	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP26 STK10 TENM3 SVIL MACF1 DOT1L	7.85e-06	192	109	6	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	7.85e-06	192	109	6	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PEG3 CMYA5 ZFHX4 TENM3 SVIL PLAT	8.09e-06	193	109	6	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP CMYA5 TENM2 SVIL RNF216 DMD	8.09e-06	193	109	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	8.09e-06	193	109	6	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KANSL1L DENND2A ARHGAP26 SVIL SYNE2 PLEKHH2	8.33e-06	194	109	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	8.33e-06	194	109	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTF3 ADCY3 ZFHX4 TENM3 LRP1 DMD	8.33e-06	194	109	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A TENM3 PDGFD PCDH15 LRP1 PLEKHH2	8.33e-06	194	109	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMYA5 SHISA9 PCDH15 TNK2 PLAT MMP17	8.83e-06	196	109	6	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMYA5 SHISA9 PCDH15 TNK2 PLAT MMP17	8.83e-06	196	109	6	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TTC14 ZFC3H1 ITK SYNE2 TENM1 MACF1	9.09e-06	197	109	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTF3 ADCY3 ZFHX4 TENM3 LRP1 DMD	9.09e-06	197	109	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTF3 ADCY3 ZFHX4 TENM3 LRP1 DMD	9.09e-06	197	109	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TTC14 ZFC3H1 ITK SYNE2 TENM1 MACF1	9.63e-06	199	109	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DENND2A TENM3 PDGFD LRP1 MACF1 PLEKHH2	9.63e-06	199	109	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DENND2A TENM3 PDGFD LRP1 MACF1 PLEKHH2	9.63e-06	199	109	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DENND2A AMPH NTF3 TENM2 PLAT MMP17	9.91e-06	200	109	6	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	DENND2A AMPH NTF3 TENM2 LRP1 MMP17	9.91e-06	200	109	6	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	BCLAF1 SYNE2 DIAPH1 MACF1 BZW1 DYNC1H1	9.91e-06	200	109	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	BIN1 TENM2 SV2B TENM1 DNAJB2 MMP17	9.91e-06	200	109	6	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHISA9 KHDRBS3 PCDH15 TENM1 TNK2 PLEKHH2	9.91e-06	200	109	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A IRS4 WNT5A RGS12 SHISA9	1.71e-05	130	109	5	56b9c3325e011f1dbaf9efc71bd6e1af4f96fda6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A ADCY3 PLAT DMD MMP17	4.11e-05	156	109	5	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 IRS4 SEMA7A PLXND1 ALB	4.36e-05	158	109	5	78b48b110b777bcc4c07cd23388bee911c0231d6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A WNT5A RGS12 SVIL MYBPC1	4.77e-05	161	109	5	be77e99faf653480c166305df3a4e93db76f0dcb
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	PEG3 CMYA5 SVIL PLAT PLEKHH2	5.06e-05	163	109	5	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 PLXND1 SV2B PDGFD PLAT	5.21e-05	164	109	5	1592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DENND2A WNT5A RGS12 SVIL MYBPC1	5.36e-05	165	109	5	c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DENND2A REEP1 ZFHX4 TENM3 SV2B	6.35e-05	171	109	5	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TENM2 TENM3 SV2B PKP3 TLL2	6.35e-05	171	109	5	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EFCAB11 SEMA7A NTF3 TENM2 RGS12	6.53e-05	172	109	5	bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EFCAB11 SEMA7A NTF3 TENM2 RGS12	6.53e-05	172	109	5	aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFC3H1 HPS3 MACF1 ALB TASOR	6.71e-05	173	109	5	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFC3H1 HPS3 MACF1 ALB TASOR	6.71e-05	173	109	5	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFC3H1 HPS3 MACF1 ALB TASOR	6.71e-05	173	109	5	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	CF-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	ARHGAP26 ZNF429 SLC25A13 SVIL SYNE2	7.08e-05	175	109	5	8020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFC3H1 HPS3 MACF1 ALB TASOR	7.08e-05	175	109	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	metastatic_Brain-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	KHDRBS3 ZFHX4 PKP3 LRP1 DOT1L	7.28e-05	176	109	5	42541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHGB CMYA5 SV2B PCDH15 MYBPC1	7.68e-05	178	109	5	d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 BCLAF1 SYNE2 DIAPH1 TASOR	7.68e-05	178	109	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|343B / Donor, Lineage, Cell class and subclass (all cells)	NOL12 NAB1 ITK SBNO2 POLR3E	7.68e-05	178	109	5	5289ac61637224ae70ffbc2d164d73116f10af40
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTF3 ADCY3 ZFHX4 TENM3 DMD	7.68e-05	178	109	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHGB CMYA5 SV2B PCDH15 MYBPC1	7.88e-05	179	109	5	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLT1 ARHGAP26 SYNE2 MACF1 PLAT	8.09e-05	180	109	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DENND2A NTF3 SVIL TENM1 MYBPC1	8.30e-05	181	109	5	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X PLXND1 CHGB PDGFD ALB	8.52e-05	182	109	5	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 ARHGAP26 PLXND1 RFX8 SV2B	8.97e-05	184	109	5	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A AMPH ADCY3 PLAT DMD	8.97e-05	184	109	5	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A AMPH ADCY3 DMD PLEKHH2	8.97e-05	184	109	5	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	NRAP CMYA5 TENM2 SVIL DMD	8.97e-05	184	109	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DENND2A NTF3 SVIL TENM1 MYBPC1	8.97e-05	184	109	5	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A AMPH ADCY3 PLAT DMD	8.97e-05	184	109	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NTF3 TENM2 TENM3 SVIL PCDH15	9.20e-05	185	109	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRAP CMYA5 TENM2 SVIL DMD	9.20e-05	185	109	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ARHGAP26 SHANK2 TENM3 LRP1 DMD	9.20e-05	185	109	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IFT172 NAB1 ZNF429 ADCY3 ALYREF	9.44e-05	186	109	5	bca5215d406f1785bf3a420201d5686071fcaca5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH NTF3 STYXL2 TENM2 DMD	9.44e-05	186	109	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NTF3 TENM2 TENM3 SVIL PCDH15	9.68e-05	187	109	5	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DENND2A TENM3 PCDH15 MACF1 PLEKHH2	9.68e-05	187	109	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BIN1 KHDRBS2 SYNE2 PCDH15 TENM1	9.68e-05	187	109	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BIN1 KHDRBS2 SYNE2 PCDH15 TENM1	9.68e-05	187	109	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NRAP CMYA5 CPLX3 SVIL DMD	9.93e-05	188	109	5	6d249fe92d51a19da19ec14bb2262d394255d577
Drug	THIP Hydrochloride; Up 200; 22.6uM; MCF7; HT_HG-U133A	AMPH IRS4 PEG3 CHRNA2 RGS12 ITK TENM1 ALB TRAPPC9	4.98e-07	199	109	9	6511_UP
Drug	aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A	BIN1 WNT5A RGS12 SHANK2 ZFHX4 HPS1 SECISBP2 RNF216	4.91e-06	197	109	8	6964_UP
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; HL60; HT_HG-U133A	FLT1 BIN1 ARHGAP26 PEG3 KHDRBS2 RGS12 SV2B PLAT	4.91e-06	197	109	8	6137_UP
Drug	Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A	AMPH BIN1 PEG3 UBOX5 SHANK2 TENM3 PLAT DNAJB2	5.09e-06	198	109	8	2623_UP
Drug	Solanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A	KANSL1L FLT1 NAB1 PLXND1 REST RGS12 HPS1 LRP1	5.29e-06	199	109	8	4087_DN
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	FLT1 IRS4 SEMA7A CHRNA2 KLF13 TENM1 LRP1	4.05e-05	193	109	7	4466_UP
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	DENND2A FLT1 THNSL1 PEG3 UBOX5 SBNO2 DIAPH1	4.19e-05	194	109	7	4301_DN
Drug	Flumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A	AMPH PLXND1 REST KLF13 SV2B HPS1 PLAT	4.33e-05	195	109	7	3712_UP
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; PC3; HT_HG-U133A	PEG3 TLE3 PKP3 HPS1 DIAPH1 SECISBP2 TXLNG	4.47e-05	196	109	7	7263_UP
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	CHRNA2 SHANK2 KLF13 TENM1 TNK2 ALB MYBPC1	4.47e-05	196	109	7	4390_UP
Drug	Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A	THNSL1 EVPL PLXND1 RGS12 SBNO2 TLE3 LRP1	4.62e-05	197	109	7	5106_UP
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; PC3; HT_HG-U133A	BIN1 ZRSR2 NOL12 EVPL UBOX5 TLE3 RNF216	4.62e-05	197	109	7	6326_DN
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; MCF7; HT_HG-U133A	REEP1 NTF3 ARHGAP26 NOL12 EVPL UBOX5 ZNF282	4.62e-05	197	109	7	2772_DN
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; HL60; HT_HG-U133A	SBNO2 MYO5C SHANK2 ZFHX4 TLE3 SVIL TNK2	4.62e-05	197	109	7	2945_UP
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A	GPAA1 EVPL ADCY3 HPS1 DIAPH1 TASOR TRAPPC9	4.62e-05	197	109	7	1674_DN
Drug	Ifosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A	MCM4 REST UBOX5 SHANK2 KHDRBS3 PDGFD PLAT	4.62e-05	197	109	7	6279_UP
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; MCF7; HT_HG-U133A	BIN1 REEP1 NOL12 PLXND1 UBOX5 SBNO2 HPS1	4.62e-05	197	109	7	2263_DN
Drug	plakin	EVPL SYNE2 MACF1 DMD DYNC1H1	4.67e-05	82	109	5	CID000018752
Drug	Isometheptene mucate; Down 200; 8.2uM; MCF7; HT_HG-U133A	NOL12 KHDRBS2 UBOX5 PDGFD HPS1 DIAPH1 DNAJB2	4.77e-05	198	109	7	6524_DN
Drug	Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	BIN1 IRS4 EFCAB11 CHRNA2 RGS12 HPS1 TNK2	4.77e-05	198	109	7	7235_UP
Drug	Austricine [10180-88-8]; Up 200; 14.2uM; PC3; HT_HG-U133A	FLT1 BIN1 NOL12 NAB1 LRP1 ZNF606 TRAPPC9	4.92e-05	199	109	7	4213_UP
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; MCF7; HT_HG-U133A	AMPH BIN1 NTF3 NOL12 PEG3 CHRNA2 SHANK2	4.92e-05	199	109	7	3614_UP
Drug	Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; PC3; HT_HG-U133A	BIN1 PEG3 ITK PKP3 TENM1 LRP1 TXLNG	4.92e-05	199	109	7	7249_UP
Drug	HA-1077 dihydrochloride; Down 200; 10uM; MCF7; HG-U133A	REEP1 EVPL CHRNA2 SBNO2 STK10 SVIL TNK2	4.92e-05	199	109	7	343_DN
Drug	Pentylenetetrazole [54-95-5]; Up 200; 29uM; PC3; HT_HG-U133A	KANSL1L NOL12 NAB1 REST ITK PKP3 LRP1	4.92e-05	199	109	7	2092_UP
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; PC3; HT_HG-U133A	REEP1 KHDRBS2 ITK KLF13 DIAPH1 TENM1 TXLNG	5.08e-05	200	109	7	6359_UP
Drug	L-Threonine	THNSL1 TARS1	6.79e-05	3	109	2	DB00156
Drug	perfluoropentane	PLAT ALB	6.79e-05	3	109	2	CID000012675
Disease	centronuclear myopathy 2 (implicated_via_orthology)	AMPH BIN1	3.83e-05	3	106	2	DOID:0111220 (implicated_via_orthology)
Disease	Drug habituation	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0013170
Disease	Drug abuse	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0013146
Disease	Prescription Drug Abuse	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C4316881
Disease	Substance-Related Disorders	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0236969
Disease	Drug Use Disorders	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0013222
Disease	Drug Dependence	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C1510472
Disease	Substance Dependence	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0038580
Disease	Substance Use Disorders	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0038586
Disease	Organic Mental Disorders, Substance-Induced	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.10e-05	115	106	5	C0029231
Disease	Substance abuse problem	TENM2 MYO5C PCDH15 ZNF606 DNAH8	6.36e-05	116	106	5	C0740858
Disease	L-Selectin measurement	EVPL POLR3E TENM1	1.88e-04	31	106	3	EFO_0008202
Disease	Angioedema	PLAT ALB	1.90e-04	6	106	2	C0002994
Disease	migraine disorder	REST STK10 SVIL LRP1 MACF1 DMD MMP17	3.13e-04	357	106	7	MONDO_0005277
Disease	calcium measurement	KHDRBS2 RGS12 TLE3 SYNE2 HPS1 MACF1 MIGA1 ALB SKAP2	4.45e-04	628	106	9	EFO_0004838
Disease	FEV/FEC ratio	FLT1 REEP1 ARHGAP26 KHDRBS2 REST ADCY3 SHISA9 SVIL SYNE2 LRP1 MIGA1 SKAP2 PTCD3	4.63e-04	1228	106	13	EFO_0004713
Disease	Hermanski-Pudlak Syndrome	HPS3 HPS1	5.65e-04	10	106	2	C0079504
Disease	Hermansky-Pudlak syndrome	HPS3 HPS1	5.65e-04	10	106	2	cv:C0079504
Disease	phosphatidylcholine measurement	IFT172 SHISA9 SYNE2 MACF1 ALB DYNC1H1	5.75e-04	284	106	6	EFO_0010226
Disease	estradiol measurement	UGT3A1 RFX8 SHANK2 ARHGAP21	6.78e-04	110	106	4	EFO_0004697
Disease	Parkinson's disease symptom measurement	PDGFD PCDH15 RNF216	6.93e-04	48	106	3	EFO_0600011
Disease	autoimmune thrombocytopenic purpura (is_marker_for)	PLAT ALB	9.72e-04	13	106	2	DOID:8924 (is_marker_for)
Disease	Acute Cerebrovascular Accidents	PRPF8 PLAT ALB	9.78e-04	54	106	3	C0751956
Disease	platelet storage pool deficiency (implicated_via_orthology)	HPS3 HPS1	1.30e-03	15	106	2	DOID:2223 (implicated_via_orthology)
Disease	Brain Ischemia	IL10RB PLAT ALB	1.33e-03	60	106	3	C0007786
Disease	Cerebral Ischemia	IL10RB PLAT ALB	1.33e-03	60	106	3	C0917798
Disease	Cerebrovascular accident	PRPF8 PLAT ALB	1.46e-03	62	106	3	C0038454
Disease	5-oxoproline measurement	GPAA1 DNAH8	1.48e-03	16	106	2	EFO_0010988
Disease	Diabetic Angiopathies	ADCY3 ALB	1.48e-03	16	106	2	C0011875
Disease	Microangiopathy, Diabetic	ADCY3 ALB	1.48e-03	16	106	2	C0025945
Disease	Charcot-Marie-Tooth disease type 2	DNAJB2 DYNC1H1	1.68e-03	17	106	2	cv:C0270914
Disease	emphysema pattern measurement	SVIL TRAPPC9	2.10e-03	19	106	2	EFO_0005850
Disease	Juvenile Myelomonocytic Leukemia	ZRSR2 ARHGAP26	2.10e-03	19	106	2	C0349639
Disease	atrial fibrillation	ARHGAP26 ZFHX4 TLE3 SYNE2 ARHGAP21 CRAMP1	2.25e-03	371	106	6	EFO_0000275
Disease	Hemorrhage	HPS1 PLAT	2.33e-03	20	106	2	C0019080
Disease	response to alcohol	FAM135B SHANK2 PCDH15	2.52e-03	75	106	3	EFO_0005526
Disease	intellectual disability (implicated_via_orthology)	KANSL1L IRS4 TRAPPC9	2.52e-03	75	106	3	DOID:1059 (implicated_via_orthology)
Disease	lung cancer	TENM2 ZRANB1	2.57e-03	21	106	2	MONDO_0008903
Disease	Lung Injury	PDGFD ALB	2.57e-03	21	106	2	C0273115
Disease	Chronic Lung Injury	PDGFD ALB	2.57e-03	21	106	2	C2350344
Disease	Nonsyndromic genetic hearing loss	REST PCDH15 DIAPH1	2.62e-03	76	106	3	cv:C5680182
Disease	functional brain measurement	NTF3 HPS1 POC1B	3.25e-03	82	106	3	EFO_0007849
Disease	complement factor H-related protein 3 measurement	KANSL1L RFX8 PCDH15 DMD	3.28e-03	169	106	4	EFO_0600056
Disease	unipolar depression, neuroticism measurement	TLL2 ARHGAP21	3.35e-03	24	106	2	EFO_0003761, EFO_0007660

Protein segments in the cluster

Peptide	Gene	Start	Entry
AYSRGVFRRDAHKSE	ALB	16	P02768
AKFLDASGAKLDYRR	BZW1	51	Q7L1Q6
TETEDRLFKHLFRGY	CHRNA2	56	Q15822
KLLRDYSADDTRKVH	DMD	2646	P11532
KKHAEYTLERGDFLS	DOT1L	211	Q8TEK3
KRLHDEKEETAGSYD	DIAPH1	196	O60610
GYLESKRFIHRDLAA	TNK2	241	Q07912
AKRSRKLVDYDSARH	AMPH	136	P49418
SFDEEKRREYLTGFH	NOL12	21	Q9UGY1
HTKRSLRYFEEESKD	GOLGA8S	151	H3BPF8
YRKTDAKRLHGLDEE	MCM4	421	P33991
DRSFRKGKDYSKHLN	REST	1066	Q13127
SKEYGHTFRSDLREE	PTCD3	516	Q96EY7
LSDEVFSLRHKKYEE	KANSL1L	821	A0AUZ9
RAFARDFAAHRKKSG	GPAA1	71	O43292
VEYKKDLESSRGHSI	NRAP	371	Q86VF7
EYKKGFEESKTRFHL	NRAP	616	Q86VF7
YGRFDSKRKDGKHLT	NAB1	256	Q13506
HRAEKLYFSDATLDK	LRP1	2386	Q07954
YRGRSYHDRKSKVDL	PDGFD	246	Q9GZP0
TLGRVKDLDTEKYFH	PLXND1	1661	Q9Y4D7
LSDRLTFLGKYREFH	NUP85	531	Q9BW27
RRISKEEYHLYKDGH	EVPL	1756	Q92817
KYFRTHLEDSLSLGR	DNAH8	3496	Q96JB1
RKDVLYTKAHETFGS	MSLNL	471	Q96KJ4
ERYFKGHKAAITSLD	POC1B	11	Q8TC44
RKRYAEHKSHRGEYS	NTF3	136	P20783
KRRYHFDTDGKGSIH	PEG3	391	Q9GZU2
HLKRNADSRTEFGKY	PLEKHH2	1066	Q8IVE3
DKLKDATERYTALHS	MACF1	3971	Q9UPN3
LLYDEHGERRDKFST	IFT172	41	Q9UG01
ARRHGDAFSLEDYTK	PCDH15	1291	Q96QU1
KAERATLRSHFRDKY	CPLX3	66	Q8WVH0
KSSADHRKSYEFEDL	DENND2A	326	Q9ULE3
LSDKHKREIYDRYGR	DNAJB2	56	P25686
ASHRNTEEEGLKYKS	BCLAF1	426	Q9NYF8
EIHYRKGKDASISLE	CMYA5	256	Q8N3K9
YIDFDHVFSRGLKKS	CRAMP1	226	Q96RY5
ARHFLGSKKRDEELY	ADCY3	901	O60266
KYGDHTLRVRAEFAD	IL10RB	81	Q08334
FKSYIRESGKADRDG	DYNC1H1	161	Q14204
LRKSGEAKYAHLSDE	KHDRBS2	116	Q5VWX1
ELRKSGEAKYFHLND	KHDRBS3	111	O75525
KKFARSDELARHYRT	KLF13	206	Q9Y2Y9
HESRSSRDKYGLDRT	FAM135B	576	Q49AJ0
GDHTESEGDLRRKLY	HPS1	96	Q92902
AKRGRKLVDYDSARH	BIN1	141	O00499
DEDHKGYLSREDFKT	EFCAB11	31	Q9BUY7
YSSHHTAEKRKRLGE	CHGB	506	P05060
RPSFSYLDKADAKHR	POLR3E	136	Q9NVU0
HSSGLRIYDREEKFL	MAP3K19	1026	Q56UN5
ASLAYFEDRHGKKRT	ITK	36	Q08881
GHRRYFVLKLETADA	IRS4	91	O14654
HLILEYTKRAASDKG	MIGA1	111	Q8NAN2
FNLTYVSHDGDDKKR	TARS1	571	P26639
RERAKHSGDYFTLLR	USP9X	1366	Q93008
SEDLTKRSHGFRTEY	UBOX5	31	O94941
PDKRFTDLKHYSDEL	SNX4	216	O95219
LSFSLKDGHYDARAR	TMCO4	121	Q5TGY1
AYFSEFLSREKRGEH	SV2B	221	Q7L1I2
RAREGDSHKESKYAV	SVIL	981	O95425
ESKRYERTEFAEHLG	SYNE2	5131	Q8WXH0
STGLADEKRKYSHFQ	HPS3	276	Q969F9
RTSDHKIVFFKGDRY	MMP17	391	Q9ULZ9
GYLEKRRKDHSFLGF	SKAP2	121	O75563
HEDSSTPFRKAKALY	ARHGAP26	751	Q9UNA1
HRKDLDLAKVGYLDS	SETD5	911	Q9C0A6
FYTKRRHLAELAAKG	SHISA9	306	B4DS77
ENSLKSDGYHKRTDR	SECISBP2	186	Q96T21
SDGYHKRTDRKSRII	SECISBP2	191	Q96T21
RTGKIYDDHRKFTLR	TENM1	1806	Q9UKZ4
HGDRRATESRDLSKY	SBNO2	881	Q9Y2G9
RTEKIYDDHRKFTLR	TENM2	1856	Q9NT68
ELKGHYAITRKALSD	RNF216	396	Q9NWF9
KDRSYDALVHFGKRG	REEP1	111	Q9H902
ADRSKKLFRHYTVGS	SHANK2	596	Q9UPX8
GKQRSSHSLDYDKDR	TASOR	666	Q9UK61
RLEKESYFESHNKGD	BRPF1	251	P55201
LHFGKERKRHLTYAE	SLC25A13	136	Q9UJS0
ADAVSYKISREHKGD	ERVK-25	911	P63136
HRDFRAKGYRKEDFL	PKP3	781	Q9Y446
TLFQKDRHTLAYDKG	PRPF8	1421	Q6P2Q9
KHFDSYIETALDGRK	UGT3A1	91	Q6NUS8
DLRHKREKDYLTSDG	ZFHX4	231	Q86UP3
KHEALSPFYSERLKE	PLAT	451	P00750
AHDKKELSYRAREIF	RGS12	756	O14924
EKRYHSGDAIAFEKS	RFX8	111	Q6ZV50
ASRRYHAKSKREEAA	STYXL2	491	Q5VZP5
RLSTFEKRKSREYEH	STK10	11	O94804
YHLTSAGEKLTEDRK	SNRNP25	96	Q9BV90
SKRGFRAHFFSDKDE	TLL2	721	Q9Y6L7
TDFIKTGHYDLRERK	THNSL1	541	Q8IYQ7
DIDKVFRTSSLKGYH	SEMA7A	341	O75326
DHRKFLLRIAYDTSG	TENM3	1791	Q9P273
KKYAHSGSRDFSRHE	TTC14	686	Q96N46
ERERIHAKGSYESAR	WNT5A	201	P41221
ESLRASEKHRGSADY	TLE3	206	Q04726
FRYLSRHKRTHTGEK	ZNF443	516	Q9Y2A4
AFSNADRYKTRHTGK	ZNF429	156	Q86V71
DFVGLDTDSRHYKKR	TRAPPC9	186	Q96Q05
ADAVSYKISREHKGD	ERVK-19	916	Q9WJR5
ARYFGKKREEDGHTH	YEATS4	31	O95619
SEGKRRFTYDHAELE	FLT1	1301	P17948
REFLLKEATESRHKY	TXLNG	326	Q9NUQ3
LDDYREDAKLSFKHV	ARHGAP21	886	Q5T5U3
HYLRLFSKRGTKDEV	ZFC3H1	1406	O60293
DHSYKRNGESERKSS	ZRSR2	386	Q15696
YDKDSVLRKALHDSL	ZRANB1	456	Q9UGI0
GKSFRYKESLKDHLR	ZNF282	636	Q9UDV7
TLKKAAVHYDRSGRS	ALYREF	131	Q86V81
EKAFRDYSALSKHER	ZNF606	546	Q8WXB4
YEGLKKATRVLESHF	MYO5C	1141	Q9NQX4
IFIRKAERSHSGKYD	MYBPC1	896	Q00872