Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF729 ZNF787 ZNF717 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 SOX8 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 SPZ1 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

5.24e-12141210030GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF729 ZNF717 ZNF311 ZNF473 ZNF273 ZNF195 ZNF429 ZNF208 SOX8 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 SPZ1 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 KDM6A ZNF726

8.41e-12124410028GO:0000978
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF729 ZNF717 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 SOX8 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 SPZ1 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 KDM6A ZNF726 ZNF443

1.19e-11145910030GO:0000977
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF729 ZNF717 ZNF311 ZNF473 ZNF273 ZNF195 ZNF429 ZNF208 SOX8 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 SPZ1 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 KDM6A ZNF726

1.40e-11127110028GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF729 ZNF717 ZNF473 ZNF208 ZNF33A ZNF43 ZNF721 ZNF85 ZNF606 ZNF726

5.01e-0456010010GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF729 ZNF717 ZNF473 ZNF208 ZNF33A ZNF43 ZNF721 ZNF85 ZNF606 ZNF726

5.44e-0456610010GO:0001216
GeneOntologyMolecularFunctionaspartic-type endopeptidase inhibitor activity

NLRP7 SORL1

8.74e-0491002GO:0019828
GeneOntologyBiologicalProcesstransposable element silencing

ZNF729 ZNF208 ZNF43 ZNF721 ZNF726

2.57e-0646985GO:0010526
GeneOntologyBiologicalProcessretrotransposition

ZNF729 ZNF208 ZNF43 ZNF721 ZNF726

3.18e-0648985GO:0032197
GeneOntologyBiologicalProcesstransposition

ZNF729 ZNF208 ZNF43 ZNF721 ZNF726

3.91e-0650985GO:0032196
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

2.23e-052982GO:0021628
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

6.68e-053982GO:0021627
HumanPhenoGastric adenocarcinoma

APC MSH3

2.13e-052242HP:0033770
DomainKRAB

ZNF729 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF85 ZNF606 ZNF726 ZNF443

1.21e-203589424PS50805
DomainKRAB

ZNF729 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF85 ZNF606 ZNF726 ZNF443

2.47e-203699424SM00349
DomainKRAB

ZNF729 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF85 ZNF606 ZNF726 ZNF443

2.63e-203709424IPR001909
DomainKRAB

ZNF729 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF85 ZNF606 ZNF726 ZNF443

2.24e-193589423PF01352
DomainZINC_FINGER_C2H2_2

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF830 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

5.77e-187759429PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF830 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

6.18e-187779429PS00028
Domain-

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

2.27e-1767994273.30.160.60
Domainzf-C2H2

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

3.78e-176939427PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

3.92e-176949427IPR013087
DomainZnf_C2H2-like

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

1.21e-167969428IPR015880
DomainZnf_C2H2

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

1.61e-168059428IPR007087
DomainZnF_C2H2

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

1.77e-168089428SM00355
Domainzf-C2H2_6

ZNF729 ZNF787 ZNF311 ZNF473 ZNF273 ZNF195 ZNF429 ZNF208 ZNF182 ZNF676 ZNF100 ZNF43 ZNF728 ZNF92 ZNF721 ZNF85 ZNF606 ZNF726 ZNF443

1.30e-153149419PF13912
DomainRUN

DENND5B DENND5A RUFY4

9.54e-0518943SM00593
DomainRUN

DENND5B DENND5A RUFY4

1.13e-0419943PS50826
DomainRUN

DENND5B DENND5A RUFY4

1.13e-0419943PF02759
DomainRun_dom

DENND5B DENND5A RUFY4

1.13e-0419943IPR004012
DomainPlexin_cytopl

PLXNA3 PLXNA1

8.82e-049942PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA1

8.82e-049942IPR013548
DomainPlexin

PLXNA3 PLXNA1

8.82e-049942IPR031148
DomainuDENN

DENND5B DENND5A

2.19e-0314942SM00800
DomainuDENN

DENND5B DENND5A

2.52e-0315942PF03456
DomainUDENN

DENND5B DENND5A

2.87e-0316942PS50946
DomainDDENN

DENND5B DENND5A

2.87e-0316942PS50947
DomainDENN

DENND5B DENND5A

2.87e-0316942SM00799
DomaindDENN

DENND5B DENND5A

2.87e-0316942SM00801
DomainDENN

DENND5B DENND5A

2.87e-0316942PF02141
DomaindDENN_dom

DENND5B DENND5A

2.87e-0316942IPR005112
DomainuDENN_dom

DENND5B DENND5A

2.87e-0316942IPR005113
DomaindDENN

DENND5B DENND5A

2.87e-0316942PF03455
DomainDENN

DENND5B DENND5A

2.87e-0316942PS50211
DomainDENN_dom

DENND5B DENND5A

2.87e-0316942IPR001194
DomainPLAT

DENND5B DENND5A

4.95e-0321942PS50095
Domain-

DENND5B DENND5A

4.95e-03219422.60.60.20
DomainPLAT

DENND5B DENND5A

4.95e-0321942PF01477
DomainPLAT/LH2_dom

DENND5B DENND5A

4.95e-0321942IPR001024
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF729 ZNF717 ZNF311 ZNF473 MED16 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ICE1 ZNF430 ZNF18 ZNF716 ZNF676 ZNF547 PPP2R5C ZNF100 ZNF33A ZNF43 ZNF257 SUPT6H ZNF92 ZNF721 ZNF606 ZNF726 ZNF443

1.70e-0913877727M734
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF729 PTDSS1 ZNF195 ZNF429 ZNF208 ZNF716 ZNF43 ZNF721 ZNF85 ZNF726

5.16e-19291011014563677
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF311 ZNF273 ZNF195 ZNF208 ZNF430 ZNF182 ZNF100 ZNF33A ZNF257 ZNF728 ZNF92 ZNF721 ZNF726

7.28e-151811011337372979
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF729 ZNF429 ZNF208 ZNF43 ZNF721 ZNF726

2.53e-1215101615885501
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF729 ZNF429 ZNF208 ZNF43 ZNF721 ZNF85 ZNF726

1.10e-104910179630514
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF208 ZNF100 ZNF43 ZNF92 ZNF85

7.96e-101610158467795
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF729 PLXNA3 ZNF473 ZNF195 ZNF429 ZNF208 ZNF18 ZNF716 ZNF43 SCAPER ZNF721 ZNF830 KDM6A ZNF726 PLXNA1

1.27e-088081011520412781
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF208 ZNF43 ZNF721

1.39e-0810101418588511
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF208 ZNF43 ZNF721

2.18e-0811101415469996
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF729 ZNF208 ZNF43 ZNF721

4.69e-0813101419850934
Pubmed

Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.

ZNF18 ZNF182 ZNF33A ZNF43

6.56e-081410142014798
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF43 ZNF92 ZNF85

1.32e-06810132023909
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF195 ZNF429 ZNF726

1.97e-069101310360839
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

2.50e-05310128806646
Pubmed

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

SUPT6H KDM6A

2.50e-053101223503590
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

2.50e-053101211241833
Pubmed

The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.

APC MSH3

2.50e-053101211691815
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

2.50e-053101220138877
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF195 ZNF429 ZNF726

2.61e-052010137479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF195 ZNF429 ZNF726

2.61e-052010132542606
Pubmed

Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

ZNF273 ZNF429 ZNF83

3.04e-052110137865130
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA1

4.99e-054101211306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA1

4.99e-054101225518740
Pubmed

Determination of cell adhesion sites of neuropilin-1.

PLXNA3 PLXNA1

4.99e-054101210725340
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA3 PLXNA1

4.99e-05410128570614
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

ZNF729 ZNF311 GART ZNF716 ZNF100 ZNF257 ZNF606 ZNF726

5.30e-05451101836168627
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

PLXNA3 PLXNA1

8.30e-055101225313870
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF429 ZNF726

8.30e-055101224190968
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF429 ZNF726

8.30e-055101220042539
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF473 KALRN APC MSH3 ME3 ZNF18 MTIF2 ZNF92 MTMR3 RNF216 ZNF83 ZNF606 KDM6A

9.00e-0512851011335914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF473 DYNC2H1 PTDSS1 EPB41L5 TRAPPC8 SCAPER CNTNAP4 ZNF606

9.83e-05493101815368895
Pubmed

Multiple genes encoding zinc finger domains are expressed in human T cells.

ZNF18 ZNF182 ZNF43

1.01e-043110132288909
Pubmed

Pathology of mouse models of intestinal cancer: consensus report and recommendations.

APC MSH3

1.24e-046101212612914
Pubmed

The human genome contains hundreds of genes coding for finger proteins of the Krüppel type.

ZNF85 ZNF83

1.24e-04610122505992
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF429 ZNF726

1.24e-046101230846446
Pubmed

Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network.

SHROOM3 NECTIN3

1.24e-046101216249236
Pubmed

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

PLXNA3 PLXNA1

1.24e-046101219480842
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF429 ZNF726

1.74e-047101222801370
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA1

1.74e-047101219063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA1

1.74e-047101219655386
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

PLXNA3 PLXNA1

1.74e-047101210520994
Pubmed

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin.

APC PPP2R5C

1.74e-047101210698523
Pubmed

Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes.

GJC2 SOX8

1.74e-047101229023979
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

CUL4A MED16 DCAF10 SUPT6H

2.04e-0499101434161765
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA1

2.31e-048101215661641
Pubmed

OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation.

CUL4A DCAF10

2.31e-048101233898171
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA1

2.31e-048101222368082
Pubmed

PlexinA2 and semaphorin signaling during cardiac neural crest development.

PLXNA3 PLXNA1

2.97e-049101211688557
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA1

2.97e-049101219909241
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 PLXNA1

3.70e-0410101218804103
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

PLXNA3 NECTIN3 CUBN PLXNA1

3.86e-04117101417145500
Pubmed

Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development.

PLXNA3 PLXNA1

4.51e-0411101231209173
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA3 PLXNA1

5.41e-0412101225839327
Pubmed

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.

PLXNA3 PLXNA1

5.41e-0412101231690636
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

PLXNA3 PLXNA1

5.41e-0412101224179230
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

PLXNA3 PLXNA1

5.41e-0412101223991118
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

PLXNA3 PLXNA1

5.41e-0412101228407732
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNA1

5.41e-0412101221270798
Pubmed

Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.

ZNF195 ZNF429 ZNF716

5.59e-0455101329997285
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

PLXNA3 PLXNA1

6.38e-0413101225959730
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNA1

6.38e-0413101210520995
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA3 PLXNA1

6.38e-0413101211604131
Pubmed

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

PLXNA3 PLXNA1

6.38e-0413101222723296
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

PLXNA3 PLXNA1

7.43e-0414101220159958
Pubmed

Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.

ZNF195 ZNF429 ZNF726

7.57e-046110138662221
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

ZNF717 MINDY4B PLXNA1

7.94e-0462101316641997
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA3 PLXNA1

9.76e-0416101217356169
Pubmed

Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.

PLXNA3 PLXNA1

9.76e-0416101218489001
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF473 MED16 ZNF273 ZNF195 APC SOX8 RFC1 SPZ1 ZNF92

1.05e-03877101920211142
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNA1

1.10e-0317101211683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNA1

1.10e-0317101217626059
Pubmed

Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation.

DENND5B DENND5A

1.24e-0318101232496646
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CUL4A CYP4V2 SHROOM3 ZNF875 PTDSS1 ZSWIM1 ZNF33A SUPT6H TANC1 DENND5A KDM6A CYB5A

1.28e-0314891011228611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZNF787 SHROOM3 MED16 PTDSS1 APC EPB41L5 ICE1 PPP2R5C SUPT6H UTP20 RRP7A TANC1

1.34e-0314971011231527615
Pubmed

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.

CFAP47 KDM6A

1.53e-0320101219377476
Pubmed

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

PLXNA3 PLXNA1

1.69e-0321101221835343
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

PTDSS1 EPB41L5 FNDC3A PODXL2 NECTIN3 TRAPPC8 SNAP47 RRP7A PLXNA1

1.84e-03952101938569033
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

DYNC2H1 PODXL2 SNAP47 SERPINB4 DENND5A

1.92e-03302101530561431
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

ZNF787 SHROOM3 RECQL RFC1 DCAF10 RNF216 WWC1

1.94e-03604101738803224
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

CUL4A KALRN FNDC3A TRAPPC8 CYB5A

1.97e-03304101532235678
Pubmed

A genomic analysis of rat proteases and protease inhibitors.

SERPINB4 A2ML1

2.03e-0323101215060002
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

PLXNA3 PLXNA1

2.21e-0324101215869472
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA3 PLXNA1

2.21e-0324101228893946
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 PTDSS1 RECQL PODXL2 NECTIN3 STS SCAPER UTP20 PLXNA1 SORL1

2.61e-0312011011035696571
InteractionZNF726 interactions

ZNF430 ZNF716 DCAF10 ZNF726

2.32e-0712964int:ZNF726
InteractionTRIM28 interactions

CUL4A ZNF311 ZNF273 ZNF195 RECQL ZNF208 FNDC3A MSH3 ZNF430 ZNF182 ZNF100 ZNF33A ZNF257 ZNF728 ZNF92 UTP20 ZNF721 ZNF85 ZNF726 ZNF443 SENP7

4.68e-0614749621int:TRIM28
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF729 ZNF429 ZNF208 ZNF430 ZNF676 ZNF100 ZNF43 ZNF257 ZNF728 ZNF85 ZNF726

3.82e-1512210111chr19p12
Cytoband19p12

ZNF729 ZNF208 ZNF430 ZNF676 ZNF100 ZNF728 ZNF85 ZNF726

2.76e-1190101819p12
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF729 ZNF787 ZNF717 ZNF311 ZNF473 ZNF273 ZNF875 ZNF195 ZNF429 ZNF208 ZNF430 ZNF18 ZNF182 ZNF716 ZNF676 ZNF547 ZNF100 ZNF33A ZNF43 ZNF257 ZNF728 ZNF92 SCAPER ZNF721 ZNF85 ZNF83 ZNF606 ZNF726 ZNF443

7.76e-22718742928
GeneFamilyPlexins

PLXNA3 PLXNA1

5.84e-049742683
CoexpressionCOATES_MACROPHAGE_M1_VS_M2_UP

ZNF729 ZNF208 PPP2R5C ZNF43 ZNF721 CAPN5 ZNF85

1.22e-07102997MM749
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

ZNF195 APC RECQL MSH3 RFC1 TRAPPC8 JAKMIP2 ZNF430 ZNF43 ZNF257 ZNF85 ZNF83 ZNF443 SORL1

1.77e-076569914M18979
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K4ME3

ZNF729 ZNF195 ZNF429 ZNF208 DNAI3 ZNF182 PPP2R5C ZNF43 ZNF721 ZNF85 ZNF726

2.86e-064979911MM863
CoexpressionTERAO_AOX4_TARGETS_SKIN_DN

ZNF729 ZNF208 ZNF43 ZNF721

3.66e-0628994MM925
CoexpressionIVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR

ZNF729 ZNF787 GART ZNF195 ZNF429 ZNF208 ZNF43 RRP7A ZNF721 ZNF830

1.48e-054839910MM1012
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

ZNF100 ZNF43 ZNF92 ZNF726 ZNF443 CYB5A

1.14e-0615010061aa9320d97ff10994ea024751790524fe133aba9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 ZNF208 FNDC3A ZNF430 ZNF83 WWC1

5.06e-06194100646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 ZNF208 FNDC3A ZNF430 ZNF83 WWC1

5.06e-061941006abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 EPB41L5 CUBN KIAA1958 ZNF83 WWC1

5.06e-0619410067002937e8903e037332a215d00fbc7c7843b33f2
ToppCellTCGA-Testes|World / Sample_Type by Project: Shred V9

ZNF729 NLRP7 ZNF716 ZNF728 SPZ1

1.04e-051281005a09b0e221b8749510002304e4d34d6a2eb8867e9
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 NECTIN3 TAFA2 WWC1 CYB5A

6.11e-0518510058ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

SHROOM3 EPB41L5 STS TANC1 WWC1

6.11e-05185100532b4e68e551d435a732f253f6ad83408c759a642
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SHROOM3 EPB41L5 TANC1 WWC1 CYB5A

7.28e-051921005efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 EPB41L5 CUBN KIAA1958 WWC1

7.46e-0519310053866667dd221612589ae50f5c52f73a183a49ce6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 SHROOM3 DYNC2H1 DNAI3 WWC1

7.46e-051931005bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 EPB41L5 CUBN KIAA1958 WWC1

7.46e-05193100582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF717 SHROOM3 STS TANC1 ARHGAP27

7.65e-05194100588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF717 SHROOM3 STS TANC1 ARHGAP27

7.65e-051941005a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 SHROOM3 DYNC2H1 TANC1 WWC1

7.83e-051951005fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 SHROOM3 DYNC2H1 TANC1 WWC1

7.83e-051951005eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SHROOM3 EPB41L5 FREM3 PLXNA1 WWC1

8.03e-051961005150554fa06868d29b0608189862eef6505ba757f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 EPB41L5 SCAPER TANC1 KDM6A

8.42e-0519810051996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_Tem|Bac-SEP / Disease, condition lineage and cell class

PLXNA3 ZNF208 DNAI3 PPP2R5C ZNF83

8.42e-051981005292b26f316f016b50d07689f84772eec46060251
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 EPB41L5 KIAA1958 WWC1 CYB5A

8.62e-0519910055f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 EPB41L5 KIAA1958 WWC1 CYB5A

8.62e-051991005725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 EPB41L5 KIAA1958 WWC1 CYB5A

8.62e-0519910055cea0d9e261903e0eaad60c28a07dff72ce65027
Diseasesmoking status measurement, triglyceride measurement

ZNF729 ZNF676

1.46e-046932EFO_0004530, EFO_0006527
Diseasemacrophage migration inhibitory factor measurement

ZNF208 TAFA2 ZNF43

3.41e-0443933EFO_0008221
DiseaseMental deterioration

TAFA2 SORL1

3.49e-049932C0234985
DiseaseMild cognitive disorder

TAFA2 SORL1

3.49e-049932C1270972
Diseaseendometrial carcinoma (is_implicated_in)

APC MSH3

6.35e-0412932DOID:2871 (is_implicated_in)
DiseaseImpaired cognition

TAFA2 SORL1

8.72e-0414932C0338656
DiseasePolyposis, Adenomatous Intestinal

APC MSH3

1.15e-0316932C2713442
DiseaseFamilial Intestinal Polyposis

APC MSH3

1.15e-0316932C2713443
DiseaseAdenomatous Polyposis Coli

APC MSH3

1.30e-0317932C0032580
Diseaseglucuronate measurement

PTDSS1 EPB41L5

1.45e-0318932EFO_0010486
Diseasetriacylglycerol 58:9 measurement

FAM227B TMEM132E

2.18e-0322932EFO_0010443
Diseaselongitudinal BMI measurement

ZNF208 JAKMIP2 ZNF257

2.24e-0382933EFO_0005937
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC MSH3

3.04e-0326932C0009405

Protein segments in the cluster

PeptideGeneStartEntry
IHWKLKELSTTTIHG

FAM227B

301

Q96M60
TQHPWEKLLNLSHSK

GVINP1

66

Q7Z2Y8
AKTHHWNITAVKLGH

A2ML1

851

A8K2U0
GQWHSVSLSAKKNHL

CNTNAP4

451

Q9C0A0
RNSKTHWNKTIHGLI

PPP2R5C

376

Q13362
RVINTSHLSIHKTWE

CAPN5

341

O15484
SVLMSGFSHKVKSHW

AMPD2

801

Q01433
NGHKKVITDIHWLSD

DNAI3

476

Q8IWG1
AWHISLSKPSEKEQH

PODXL2

431

Q9NZ53
AKKNISHISSSHWGE

ENTHD1

501

Q8IYW4
TKGSLLWVLDHTKTS

MSH3

556

P20585
SEHQSHQEAISKIKW

JAKMIP2

186

Q96AA8
HVIWKGSLTSLKHHK

MTIF2

666

P46199
LHAVWEHKLGSQVSL

WWC1

131

Q8IX03
IHNHSTFVGKVWLTV

GJC2

16

Q5T442
GTKKIWHCESNRSHT

KDM6A

1016

O15550
DLESGTKLWHLVKNH

PLXNA1

1646

Q9UIW2
DQETGTKLWHLVKNH

PLXNA3

1621

P51805
KKLVRLTIDTHSHHW

MINDY4B

406

A8MYZ0
KLNTKVCTLHGHTSW

DCAF10

241

Q5QP82
KGHIHATEIRKWVTT

KALRN

1201

O60229
EIQKHNHSKSTWLIL

CYB5A

16

P00167
KHSERHHKTVEWGSL

LMNTD2

256

Q8IXW0
HHVTVWGEATRSAKK

LMNTD2

416

Q8IXW0
VSTLKAVAVTHSLWH

PRNT

61

Q86SH4
KGTVTVHLWKDSTGH

IP6K3

66

Q96PC2
VHLWKDSTGHLSLVA

IP6K3

71

Q96PC2
WLHNGVKLALHVEKS

MED16

136

Q9Y2X0
CSWTAITHKSKHLEI

CUBN

2831

O60494
HKNLKNHSIWGSSSK

DYNC2H1

2451

Q8NCM8
SAQVAHWLDGTKSIK

EPB41L5

91

Q9HCM4
VKSTSWHHSDLLRKG

ICE1

786

Q9Y2F5
SVKGKIHSHSFKITW

FNDC3A

571

Q9Y2H6
NSVHVHISKSKVGWL

BPI

171

P17213
HISKSKVGWLIQLFH

BPI

176

P17213
KHSGRKLQWQTTLGH

CUL4A

561

Q13619
HGLQVKQGKSALWSH

DENND5B

791

Q6ZUT9
GWEHKKSLQILHTFT

CYP4V2

251

Q6ZWL3
HGLQVKQGKSALWSH

DENND5A

806

Q6IQ26
TIHDKGHLATMLNSW

ME3

161

Q16798
SWADKVKAHHTGSTA

SCAPER

221

Q9BY12
KHHVTWTLDLSNTGK

CFAP47

1226

Q6ZTR5
LSALESTKWLHHLSV

MTMR3

376

Q13615
STKWLHHLSVLLKSA

MTMR3

381

Q13615
LHTKDKVSLCHLGWS

MKNK1

161

Q9BUB5
EVWLSDGKHTTHRKV

FREM3

1281

P0C091
VTLWGKVVSSANHHK

TAFA2

21

Q8N3H0
KPAETLSKIWSHVHS

UTP20

2456

O75691
GLWKSKDDNHSKRSH

SENP7

571

Q9BQF6
GESIWKTLETHSNKT

SORL1

1596

Q92673
SSITILEKGHAKHWF

SNAP47

111

Q5SQN1
QWHVTSELLTGAKHS

TMEM132E

351

Q6IEE7
SWLGKHSSTGKHDRI

RFC1

961

P35251
LIQHDSEAIISTWHK

ARHGAP27

591

Q6ZUM4
GTHKKEAEWSHVQRL

RUFY4

331

Q6ZNE9
LIGKWHLGMSCHSKT

STS

131

P08842
SLKKQHLTWSHTLKE

SHLD3

96

Q6ZNX1
HSWHTTKSGEKQPDA

SHROOM3

161

Q8TF72
SKKTGISSSHLQALW

TANC1

876

Q9C0D5
KTLTHLTLAGHIEWE

NLRP7

731

Q8WX94
SSQDIKWALHELKGH

RNF216

386

Q9NWF9
HLHNAELSKTLGKLW

SOX8

126

P57073
INRSGTWKREHSKHS

APC

2541

P25054
VSTESHPVKSGIHKW

RRP7A

141

Q9Y3A4
WATCHTGESTSHVKK

ERVK-25

676

P63136
LNASSSKEHVKWVHA

RECQL

161

P46063
SKGENHLTVTWKVSD

SUPT6H

1361

Q7KZ85
NWSSALTKHKRIHTG

ZNF100

411

Q8IYN0
NWSSTLTKHKRIHTG

ZNF273

356

Q14593
NWSSTLTKHKRIHTG

ZNF273

496

Q14593
KSHLIVHWRTHTGEK

ZNF182

246

P17025
NWSSTLTKHKIIHTG

ZNF92

211

Q03936
GKAFSWSSILTEHKI

ZNF676

511

Q8N7Q3
WSSILTEHKIIHTGE

ZNF676

516

Q8N7Q3
FGWSIALNQHKKIHT

ZNF721

666

Q8TF20
KWSSTLTKHKIIHTG

ZNF728

406

P0DKX0
SWSASLTKHKRIHTG

ZNF716

251

A6NP11
GMTWSHGLSVSKVLH

SERPINB4

316

P48594
TLAWKLAQSHHVKQV

GART

16

P22102
WSSKLTEHKITHTGE

ZNF43

521

P17038
WSSTLTKHKIIHTGE

ZNF43

661

P17038
WDKSNLTKHQRSHTG

ZNF33A

366

Q06730
KSFLTIHQWTHTGEK

ZNF717

491

Q9BY31
WSSNLTEHKKIHTRE

ZNF726

436

A6NNF4
NWSSTLTKHKRIHTG

ZNF430

411

Q9H8G1
WSSNLMEHKKIHTGE

ZNF208

436

O43345
NWSSNLMEHKKIHTG

ZNF208

1011

O43345
WSSTLITHQRVHTGK

ZNF547

251

Q8IVP9
ASLSSLHRHKKTHWK

ZNF443

626

Q9Y2A4
NWSSTLTKHKVIHTG

ZNF429

351

Q86V71
KSELLWQTHVLGKQH

ZNF830

61

Q96NB3
HIVQVSSSSKHWKLQ

TRAPPC8

1121

Q9Y2L5
KWSSVLTKHKIIHTG

ZNF85

576

Q03923
HWSKQHTELSKLIKS

SPZ1

256

Q9BXG8
WSSSLDKHQRSHLGK

ZNF18

531

P17022
TWKSNLITHQRTHSG

ZNF875

311

P10072
SWKSNLKTHQRTHSG

ZNF875

451

P10072
SKWSETLDKHLAVTH

ZSWIM1

431

Q9BR11
SHKSTSGQAKWQGHI

RPTN

211

Q6XPR3
HWASFKDIHTTTGKI

PTDSS1

246

P48651
WFSDLTKHKRIHTGE

ZNF195

421

O14628
WFSDITKHKKTHTGE

ZNF195

561

O14628
KSSLVNHWRIHTGEK

ZNF83

301

P51522
WSSYLIQHKKTHTGE

ZNF606

411

Q8WXB4
KRKHQVWSTHELDGS

ZNF311

631

Q5JNZ3
KWSSKLTVHKVVHTG

ZNF729

386

A6NN14
KWSSKLTVHKVIHTG

ZNF729

806

A6NN14
QSTYLWHQKTHTGEK

ZNF473

276

Q8WTR7
WSSALTTLTQHKIIH

ZNF257

411

Q9Y2Q1
CGKSFSHWSKLTRHQ

ZNF787

71

Q6DD87
NLSKLVSWAHSHGTI

KIAA1958

11

Q8N8K9
WEKIHGKSSQTVAVH

NECTIN3

91

Q9NQS3