Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsingle-stranded DNA 3'-5' DNA exonuclease activity

EXD2 POLG

7.08e-056442GO:0008310
GeneOntologyMolecularFunctionsingle-stranded DNA exodeoxyribonuclease activity

EXD2 POLG

2.11e-0410442GO:0008297
GeneOntologyMolecularFunctionmanganese ion binding

B4GALT7 PPEF2 EXD2

5.14e-0471443GO:0030145
GeneOntologyMolecularFunction3'-5'-DNA exonuclease activity

EXD2 POLG

5.58e-0416442GO:0008296
GeneOntologyMolecularFunctionsnRNP binding

SNRPB SNRPN

5.58e-0416442GO:0070990
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

CUL4A HECW1 STUB1 JADE2 HERC2P3 HECTD4

5.63e-04473446GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

CUL4A HECW1 STUB1 JADE2 HERC2P3 HECTD4

8.52e-04512446GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

CUL4A HECW1 STUB1 JADE2 HERC2P3 HECTD4

1.04e-03532446GO:0016755
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

NAA50 JADE2

1.17e-0323442GO:0010485
GeneOntologyMolecularFunctionubiquitin protein ligase activity

CUL4A HECW1 STUB1 JADE2 HERC2P3

1.31e-03372445GO:0061630
GeneOntologyMolecularFunctionDNA exonuclease activity, producing 5'-phosphomonoesters

EXD2 POLG

1.38e-0325442GO:0016895
GeneOntologyMolecularFunctionDNA-directed DNA polymerase activity

POLM POLG

1.38e-0325442GO:0003887
GeneOntologyMolecularFunctionacyltransferase activity

CUL4A NAA50 HECW1 STUB1 JADE2 HERC2P3 HECTD4

1.41e-03775447GO:0016746
GeneOntologyMolecularFunctionDNA exonuclease activity

EXD2 POLG

1.49e-0326442GO:0004529
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

CUL4A HECW1 STUB1 JADE2 HERC2P3

1.76e-03398445GO:0061659
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

SMARCA1 POLM EXD2 POLG

2.60e-03262444GO:0140097
GeneOntologyMolecularFunctionDNA polymerase activity

POLM POLG

3.17e-0338442GO:0034061
GeneOntologyCellularComponentU5 snRNP

PRPF8 SNRPB SNRPN

2.07e-0525453GO:0005682
GeneOntologyCellularComponentU4/U6 x U5 tri-snRNP complex

PRPF8 SNRPB SNRPN

1.41e-0447453GO:0046540
GeneOntologyCellularComponentspliceosomal tri-snRNP complex

PRPF8 SNRPB SNRPN

1.51e-0448453GO:0097526
GeneOntologyCellularComponentU4 snRNP

SNRPB SNRPN

3.48e-0413452GO:0005687
GeneOntologyCellularComponentU2-type prespliceosome

SNRPB SNRPN

6.78e-0418452GO:0071004
GeneOntologyCellularComponentprespliceosome

SNRPB SNRPN

6.78e-0418452GO:0071010
GeneOntologyCellularComponentspliceosomal snRNP complex

PRPF8 SNRPB SNRPN

1.16e-0396453GO:0097525
GeneOntologyCellularComponentcatalytic step 2 spliceosome

PRPF8 SNRPB SNRPN

1.19e-0397453GO:0071013
GeneOntologyCellularComponentU2-type spliceosomal complex

PRPF8 SNRPB SNRPN

1.19e-0397453GO:0005684
GeneOntologyCellularComponentsmall nuclear ribonucleoprotein complex

PRPF8 SNRPB SNRPN

1.58e-03107453GO:0030532
GeneOntologyCellularComponentU2 snRNP

SNRPB SNRPN

1.65e-0328452GO:0005686
GeneOntologyCellularComponentU2-type catalytic step 2 spliceosome

PRPF8 SNRPB

2.03e-0331452GO:0071007
GeneOntologyCellularComponentSm-like protein family complex

PRPF8 SNRPB SNRPN

2.14e-03119453GO:0120114
GeneOntologyCellularComponentU1 snRNP

SNRPB SNRPN

2.29e-0333452GO:0005685
DomainsnRNP-assoc_SmB/SmN

SNRPB SNRPN

5.42e-062442IPR017131
DomainRNaseH-like_dom

PRPF8 EXD2 POLG

5.73e-0469443IPR012337
DomainSm

SNRPB SNRPN

9.04e-0419442SM00651
DomainLSM

SNRPB SNRPN

9.04e-0419442PF01423
DomainLSM_dom_euk/arc

SNRPB SNRPN

9.04e-0419442IPR001163
DomainLSM_dom

SNRPB SNRPN

1.22e-0322442IPR010920
DomainSAM_2

ARAP3 DLC1

4.61e-0343442PF07647
Domain-

EXD2 POLG

5.48e-03474423.30.420.10
DomainRhoGAP

ARAP3 DLC1

9.38e-0362442SM00324
Pubmed

The cardiac form of the tissue-specific SmN protein is identical to the brain and embryonic forms of the protein.

SNRPB SNRPN

1.71e-0624628510173
Pubmed

Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci.

SNRPB SNRPN

1.71e-06246210556313
Pubmed

A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'.

SNRPB SNRPN

5.13e-0634622522186
Pubmed

Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.

MYO7A SULF1

5.13e-06346225370455
Pubmed

Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs.

SNRPB SNRPN

5.13e-0634627744014
Pubmed

DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress.

CUL4A CHEK1

5.13e-06346219276361
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SH3GLB2 STUB1 PRPF8 WDR17 JADE2 MTMR10 SULF1 MED13 POLG HECTD4

5.55e-061285461035914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TAOK2 SH3GLB2 RBM12 JADE2 SULF1 MED13 HECTD4

5.80e-0652946714621295
Pubmed

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

CUL4A CHEK1

1.03e-05446216137618
Pubmed

ZNRF1 interacts with tubulin and regulates cell morphogenesis.

STUB1 DNAAF4

1.03e-05446219737534
Pubmed

Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia.

STUB1 DNAAF4

1.03e-05446219423554
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TAOK2 FRYL ZNF276 ARAP3 MYO7A MED13 POLG RTTN HECTD4

1.22e-05110546935748872
Pubmed

GYF domain proteomics reveals interaction sites in known and novel target proteins.

RBM12 SNRPB

1.71e-05546216120600
Pubmed

The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus.

SNRPB SNRPN

1.71e-05546218362360
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

SMARCA1 CUL4A HECW1 CENPI HECTD4

1.99e-0525046533536335
Pubmed

The Sm core components of small nuclear ribonucleoproteins promote homologous recombination repair.

CHEK1 SNRPB

2.56e-05646234768043
Pubmed

CRL4(CDT2) targets CHK1 for PCNA-independent destruction.

CUL4A CHEK1

3.58e-05746223109433
Pubmed

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.

CUL4A DLC1

3.58e-05746224082123
Pubmed

A novel function for human factor C1 (HCF-1), a host protein required for herpes simplex virus infection, in pre-mRNA splicing.

SNRPB SNRPN

3.58e-05746212456665
Pubmed

Multiple protein: protein interactions between the snRNP common core proteins.

SNRPB SNRPN

4.77e-0584629417867
Pubmed

Death by splicing: tumor suppressor RBM5 freezes splice-site pairing.

PRPF8 SNRPB

4.77e-05846218951082
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

CUL4A CASP10 PYGL NLRP7 POLG

5.79e-0531346520800603
Pubmed

Ataxin-3 promotes genome integrity by stabilizing Chk1.

CUL4A CHEK1

6.12e-05946228180282
Pubmed

Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2.

SNRPB SNRPN

7.65e-051046215105431
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

GNAL ARAP3 PPEF2 SNRPB POLM PTGIR CENPI

1.04e-0483246736724073
Pubmed

The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins.

SNRPB SNRPN

1.12e-041246211713266
Pubmed

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.

CUL4A NAA50 STUB1 PRPF8

1.23e-0419246432176739
Pubmed

A functional interaction between the survival motor neuron complex and RNA polymerase II.

SNRPB SNRPN

1.32e-041346211149922
Pubmed

Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones.

STUB1 DNAAF4

1.32e-041346215189447
Pubmed

Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli.

SNRPB SNRPN

1.54e-041446210725331
Pubmed

Selection system for genes encoding nuclear-targeted proteins.

RBM12 BMP2K

1.54e-04144629853615
Pubmed

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

CUL4A HECW1 STUB1

1.60e-047946327325702
Pubmed

Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon.

CUL4A SNRPB SNRPN

1.72e-048146326990986
Pubmed

HIV-1 Vpr-a still "enigmatic multitasker".

CUL4A CHEK1

2.03e-041646224744753
Pubmed

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.

WNT5B SFRP2

2.30e-041746228292423
Pubmed

HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.

CUL4A HECW1 STUB1

2.35e-049046335671810
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

GNAL STUB1 PRPF8 WDR17

2.49e-0423146436597993
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

CUL4A CHEK1 RPS29 DLC1 STUB1 PRPF8 SNRPB

2.68e-0497146733306668
Pubmed

Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.

SFRP2 SULF1

2.88e-041946220185795
Pubmed

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.

WNT5B SFRP2

3.54e-042146217943183
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

HECW1 STUB1

3.54e-042146237005481
Pubmed

Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.

WNT5B SFRP2

3.89e-042246212815618
Pubmed

Motor neurons with axial muscle projections specified by Wnt4/5 signaling.

WNT5B SFRP2

3.89e-042246219285468
Pubmed

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.

SNRPB SNRPN

3.89e-042246218984161
Pubmed

A role for Wnt/beta-catenin signaling in lens epithelial differentiation.

WNT5B SFRP2

5.04e-042546212812787
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

CUL4A SH3GLB2 PYGL FRYL RBM12 RPS29 STUB1 SNRPB

5.82e-04145546822863883
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

WNT5B SFRP2

5.88e-042746217804636
Pubmed

Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients.

SFRP2 SULF1

6.33e-042846225082703
Pubmed

Mechanism of 5' splice site transfer for human spliceosome activation.

PRPF8 SNRPB

6.79e-042946230975767
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TAOK2 RBM12 MED13

6.89e-0413046312421765
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

RBM12 PRPF8 SNRPN

6.89e-0413046335545047
Pubmed

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.

PRPF8 SNRPB

7.27e-043046228076346
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

WNT5B SFRP2

7.27e-043046215880404
Pubmed

Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.

DLC1 SULF1

7.27e-043046220083228
Pubmed

An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage.

RPS29 STUB1

7.77e-043146235066290
Pubmed

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

PRPF8 SNRPB

7.77e-043146228878014
Pubmed

KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors.

WNT5B SFRP2

7.77e-043146237838801
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SH3GLB2 FRYL HECW1 STUB1 SNRPN

8.45e-0456046521653829
Pubmed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

PRPF8 SNRPB

8.80e-043346228781166
Pubmed

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.

PRPF8 SNRPB

9.35e-043446215146077
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

SMARCA1 CUL4A PRPF8 SNRPB

9.38e-0432946434316702
Pubmed

Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.

WNT5B SFRP2

9.90e-043546223376422
Pubmed

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

WNT5B SFRP2

9.90e-043546219185060
Pubmed

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.

WNT5B MYO7A

9.90e-043546232907846
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

WNT5B SFRP2

1.05e-033646212412008
Pubmed

Integrated analysis of Wnt signalling system component gene expression.

WNT5B SFRP2

1.11e-033746235831952
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

SMARCA1 CUL4A FRYL

1.17e-0315646322952844
Pubmed

Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.

WNT5B SFRP2

1.17e-033846221041481
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

SMARCA1 CUL4A STUB1 SNRPB SNRPN

1.20e-0360646536538041
Pubmed

Roles of tau protein in health and disease.

TAOK2 STUB1

1.29e-034046228386764
Cytoband7p13

HECW1 POLM

7.11e-04394627p13
GeneFamilyDNA polymerases

POLM POLG

7.50e-0423322535
CoexpressionHU_ANGIOGENESIS_UP

HECW1 STUB1 JADE2

6.58e-0621463M6967
ToppCellfacs-Trachea-nan-24m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 LRRC4B DNAAF4 BMP15 CENPI

9.57e-071734652226505610af1becc253d0a5550627144ef0ed6b
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALT7 POLM RTTN CENPI

2.58e-0516646421ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 LRRC4B BMP15 CENPI

3.25e-0517646477c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRYL SFRP2 SULF1 SNRPN

3.55e-0518046467c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WNT5B NPDC1 ARAP3 SULF1

4.29e-0518946412b6f1c3bf526b90e112374bf937701f645c5780
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.38e-0519046470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.47e-0519146439092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPDC1 ARAP3 DLC1 MYO7A

4.47e-0519146488f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WNT5B ARAP3 SULF1

4.47e-05191464b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 PTGIR SULF1

4.47e-051914641caf726bd07fdca389e678fc16304a6ef1790423
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPDC1 ARAP3 DLC1 MYO7A

4.47e-051914641924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 PTGIR SULF1

4.47e-051914643d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.47e-05191464ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 PTGIR SULF1

4.56e-051924644022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.56e-051924645105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.56e-05192464d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 PTGIR SULF1

4.56e-051924649333aba0d04203ccccad78d82bf6359922f810a7
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LRRC4B SFRP2 SULF1

4.65e-0519346409de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WNT5B NPDC1 ARAP3

4.65e-051934642e72309607902dabe3218888b22a77fe941f3570
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

THSD4 NPDC1 LRRC4B SULF1

4.65e-051934643d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

THSD4 SFRP2 SNRPB SULF1

4.75e-051944645759c83308df017f1faae248e9b85388e25254f0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.75e-0519446490efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.75e-05194464e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.75e-05194464df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.84e-05195464edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.84e-05195464803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPDC1 ARAP3 DLC1 MYO7A

4.84e-0519546412ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.84e-051954644f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.94e-05196464802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.94e-051964642b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

4.94e-05196464fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

5.04e-0519746480e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

5.04e-05197464ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR SULF1

5.04e-0519746437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SFRP2 DLC1 PTGIR SULF1

5.14e-051984649541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

GNAL SFRP2 DLC1 SULF1

5.24e-0519946413ff7409e200a0b46cdb7924d15ef33639693622
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

THSD4 DLC1 PTGIR SULF1

5.24e-051994649503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TAOK2 CASP10 ARAP3 DLC1

5.34e-05200464dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TAOK2 CASP10 ARAP3 DLC1

5.34e-05200464a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

TAOK2 CASP10 NLRP7

3.42e-041324634e37400ae7375e6986f060234c373194603346f8
ToppCellURO-Lymphocyte-T_NK-CD8_TCM|URO / Disease, Lineage and Cell Type

NPDC1 RPS29 SNRPN

4.14e-0414146353aef819f505238011f8a3202445f31055791d05
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT5B SFRP2 SNRPN

4.41e-041444630322fef818a963be00535d5f141f028d43de5c6a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT5B SFRP2 SNRPN

4.50e-04145463590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP2 SULF1 CENPI

4.59e-0414646386cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DLC1 MYO7A EXD2

4.96e-041504636f7087a051a2f05c5611ff65a945c01736d5ec2b
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

TAOK2 CASP10 NLRP7

5.26e-04153463a156710217ef07c07a80ca6504fa0784d86380fa
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFRP2 SULF1 POLG

5.46e-041554638e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 SULF1

5.56e-04156463363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP2 DLC1 SULF1

5.56e-04156463d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-3|TCGA-Colorectal / Sample_Type by Project: Shred V9

LRRC4B B4GALT7 PTGIR

5.56e-04156463b464871ad7c8ce0d58013a27996639eac1e526d8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HECW1 BMP2K POLM

5.67e-0415746329622bac6b16bb39cec4319bf4c4f92d33345e8a
ToppCellcontrol-B_cell|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

GNAL RPS29 HECW1

5.67e-041574631269b55f2ef6a493f6116b131cc5cc7b8897d63e
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

LRRC4B PPEF2 PTGIR

5.77e-041584638d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPEF2 WDR17 CENPI

5.77e-04158463d72d6527dc50207ddbada262460d3c4bac249a19
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR

5.88e-041594632607b562903228274fbd96168ba826782fab0b53
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 PTGIR

5.88e-04159463e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WNT5B HECW1 CENPI

5.88e-041594637ed659163f45e0c4df4782997c0786900c8186c8
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PYGL DNAAF4 RTTN

5.99e-0416046319105debef96ea0c267d6a1d332303ec668ae47e
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMARCA1 THSD4 DNAAF4

6.66e-0416646337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellremission-HSPC|World / disease stage, cell group and cell class

DLC1 DNAAF4 EXD2

6.66e-04166463d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMARCA1 THSD4 DNAAF4

6.66e-0416646381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WNT5B ARAP3

6.66e-041664638e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WNT5B CASP10

6.66e-041664638e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 SFRP2 SULF1

6.78e-04167463d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 SFRP2 SULF1

6.78e-041674637abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellTuft-tuft-1|World / Class top

WNT5B MYO7A RTTN

6.90e-041684638ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

ARAP3 DLC1 MED13

6.90e-0416846300646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 THSD4 ARAP3

6.90e-0416846306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GNAL PTGIR DNAAF4

6.90e-04168463a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

NPDC1 ARAP3 SULF1

6.90e-04168463aca34c51758c65925ad24110294a72b2dea6db72
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

NPDC1 ARAP3 SULF1

6.90e-041684638c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 THSD4 ARAP3

6.90e-041684631002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP2 WDR17 HECTD4

7.14e-041704635570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT5B SFRP2 SNRPN

7.14e-0417046314aa86a4f526ed6986afcb28c49225522055550c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 SULF1 CENPI

7.26e-04171463b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DLC1 PTGIR CENPI

7.26e-04171463a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 SULF1 CENPI

7.26e-04171463b0373ed8283ee1792b6a490bff93906546978593
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRYL SULF1 MED13

7.26e-041714636a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRYL SULF1 MED13

7.26e-041714639be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PYGL LRRC4B DLC1

7.39e-04172463553701349444eb366df3c11f54bb093434f153c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PYGL LRRC4B DLC1

7.39e-0417246308a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellFLU-Healthy-3|FLU / Virus stimulation, Condition and Cluster

TAOK2 CHEK1 CENPI

7.51e-0417346332b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCellFLU-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

TAOK2 CHEK1 CENPI

7.51e-0417346326e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 SFRP2 SULF1

7.51e-0417346330d67738633493d47f06ae452424382f069b6c0a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GNAL CHEK1 CENPI

7.51e-04173463506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THSD4 LRRC4B SFRP2

7.51e-04173463b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 SFRP2 SULF1

7.64e-04174463a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GNAL DLC1 SULF1

7.64e-04174463321c6cae614d28feeee266eeb3499f2053ab79e0
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B4GALT7 POLM CENPI

7.76e-041754636751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

NPDC1 ARAP3 SULF1

7.76e-041754630a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GNAL DLC1 SULF1

7.76e-0417546390e29945aa861082c94bb4f331161adc3a6ef899
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NPDC1 ARAP3 SULF1

7.89e-0417646352af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 SULF1

7.89e-041764639bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT5B SFRP2 SNRPN

7.89e-0417646305ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 DLC1 SULF1

7.89e-041764633f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GNAL DLC1 SULF1

7.89e-04176463e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellwk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THSD4 PYGL SULF1

8.02e-04177463b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NPDC1 ARAP3 DLC1

8.02e-041774636da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 SFRP2 SULF1

8.16e-04178463c413861148129be1ee94f2ceb5999840217eebe5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GNAL DLC1 SULF1

8.16e-04178463431e7557b8e8764e16e9e48368ce6bfa3c61561a
DrugThioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; PC3; HT_HG-U133A

NPDC1 ZNF276 RBM12 POLG BMP15 CENPI

2.39e-061974562073_DN
DrugBrVarafUTP

PYGL POLM POLG

1.42e-0524453CID005273539
DrugAC1L1CVV

CHEK1 POLM POLG

1.82e-0526453CID000027281
Drug15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A

ZNF276 CHEK1 DLC1 SULF1 POLG

3.76e-051924556990_DN
Drugbenzo(c)phenanthrene

TAOK2 LRRC4B POLG

3.78e-0533453CID000009136
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

TAOK2 SMARCA1 MYO7A SULF1 POLG

4.05e-051954552702_UP
DrugHymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A

DLC1 BMP2K JADE2 POLG BMP15

4.15e-051964553383_DN
DrugHesperidin [520-26-3]; Up 200; 6.6uM; PC3; HT_HG-U133A

TAOK2 CASP10 GNAL DLC1 HECW1

4.25e-051974556714_UP
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; MCF7; HT_HG-U133A

TAOK2 SMARCA1 DLC1 BMP2K JADE2

4.25e-051974553531_UP
Drug5-aza-2′-deoxycytidine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TAOK2 FRYL DLC1 BMP2K POLG

4.46e-05199455920_DN
DrugL-BVAU

PYGL POLM POLG

5.80e-0538453CID000667554
Diseaseprimary ovarian insufficiency (is_implicated_in)

POLG BMP15

6.33e-058452DOID:5426 (is_implicated_in)
Diseasetauopathy (implicated_via_orthology)

SNRPB SNRPN

1.02e-0410452DOID:680 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (implicated_via_orthology)

PRPF8 POLG

2.36e-0415452DOID:0050908 (implicated_via_orthology)
Diseasecentral nervous system disease (implicated_via_orthology)

TAOK2 SMARCA1

2.69e-0416452DOID:331 (implicated_via_orthology)
DiseaseC-X-C motif chemokine 10 measurement

PPEF2 BMP2K HECTD4

6.21e-04109453EFO_0008056

Protein segments in the cluster

PeptideGeneStartEntry
GHLYRVQKCAALNQM

ARAP3

1036

Q8WWN8
RYNNRERLLNKMCGT

CHEK1

156

O14757
HGGIRCALKRMYVNN

BMP2K

71

Q9NSY1
MCRLQDQGLILYHQH

POLM

351

Q9NP87
AALCRHKQYMGNRFI

RBM12

486

Q9NTZ6
MAGYQFLDRCNHLKR

MTMR10

441

Q9NXD2
MLLHLCSVKNLYQNR

HECW1

1

Q76N89
LSKQHYRLCNGMSNR

B4GALT7

206

Q9UBV7
NNKGHRILRLRFMCQ

BMP15

196

O95972
YLAMRQRNNLLCNGL

EXD2

191

Q9NVH0
HLRQDLERVRNLCYM

JADE2

471

Q9NQC1
CRVDHSQNQKRLYIM

NAA50

61

Q9GZZ1
DRNMQINRHQYCALK

FRYL

1096

O94915
YRKHCLEQGKQQLMP

POLG

656

P54098
VRYQCLKGNMLTRHR

EVC2

321

Q86UK5
CLRYLMAVQNHLLSN

HECTD4

446

Q9Y4D8
CRDIIQRMHLKQYEL

GNAL

366

P38405
YQHQRQQMLCLERHK

NPDC1

251

Q9NQX5
RALCYLKMQQHEQAL

STUB1

66

Q9UNE7
MLYKQLRQACEDHVQ

CUL4A

101

Q13619
NKMPLLYLNRAACHL

DNAAF4

321

Q8WXU2
YRMNRNHRGLCVIVN

CASP10

276

Q92851
NQLCFIMHRYRKNLT

CENPI

601

Q92674
LVNLRYLNLGMCNLK

LRRC4B

206

Q9NT99
LQKYNMQFLIRSHEC

PPEF2

476

O14830
LQQLCMYLRNRLNFH

RTTN

256

Q86VV8
NLQLCHGIEYQNMRL

SFRP2

46

Q96HF1
NRHGLIRKYGLNMCR

RPS29

26

P62273
NILMQLRKCCNHPYL

SMARCA1

451

P28370
QHIDYRMRCILQDGR

SNRPN

11

P63162
QCYRHMLDLQKQLGR

SH3GLB2

266

Q9NR46
QHIDYRMRCILQDGR

SNRPB

11

P14678
LQCRQYKRKMLLARH

TAOK2

641

Q9UL54
MLCDLLRNHKCNLQY

NLRP7

751

Q8WX94
HLRLGQIQRYCELMV

WDR17

826

Q8IZU2
LCGLLQMLVYREQHR

HERC2P3

721

Q9BVR0
KAVHNLLERCLMNRN

MED13

121

Q9UHV7
QQAMRYLRNHCLDQV

DLC1

1096

Q96QB1
VCRQGYNMLNLLIHR

PRPF8

496

Q6P2Q9
CRMYRQQKRHQGSLG

PTGIR

211

P43119
GCNKVFMIDRYLQRH

ZNF276

471

Q8N554
PGQRKLCQLYQEHMA

WNT5B

56

Q9H1J7
MQHRQVLCRQVYANR

THSD4

696

Q6ZMP0
RQLLNCLHVITMYNR

PYGL

576

P06737
HVQLMELRSCQGYKQ

SULF1

826

Q8IWU6
HNCRKNYGLMRLGFL

MYO7A

781

Q13402