Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	AP-type membrane coat adaptor complex	AP1B1 AP2B1 VPS39 TBC1D5	4.95e-05	48	88	4	GO:0030119
GeneOntologyCellularComponent	t-UTP complex	NOL11 HEATR1	5.24e-05	3	88	2	GO:0034455
GeneOntologyCellularComponent	eukaryotic translation initiation factor 2 complex	EIF2S3 EIF2S3B	2.60e-04	6	88	2	GO:0005850
GeneOntologyCellularComponent	clathrin adaptor complex	AP1B1 AP2B1 TBC1D5	2.98e-04	31	88	3	GO:0030131
GeneOntologyCellularComponent	DNA-dependent protein kinase-DNA ligase 4 complex	LIG4 XRCC6	3.63e-04	7	88	2	GO:0005958
GeneOntologyCellularComponent	cis-Golgi network	HOOK3 AKAP9 MPPE1 PHTF1	4.58e-04	85	88	4	GO:0005801
GeneOntologyCellularComponent	clathrin vesicle coat	AP1B1 AP2B1 TBC1D5	5.47e-04	38	88	3	GO:0030125
GeneOntologyCellularComponent	nonhomologous end joining complex	LIG4 XRCC6	6.19e-04	9	88	2	GO:0070419
GeneOntologyCellularComponent	inner dynein arm	DNAH10 DNAI7	7.71e-04	10	88	2	GO:0036156
GeneOntologyCellularComponent	membrane coat	AP1B1 AP2B1 VPS39 TBC1D5	1.05e-03	106	88	4	GO:0030117
GeneOntologyCellularComponent	coated membrane	AP1B1 AP2B1 VPS39 TBC1D5	1.05e-03	106	88	4	GO:0048475
GeneOntologyCellularComponent	cilium	DLG5 AKAP9 DNAH10 PTPRK CEP89 BBS7 RTTN ARMC9 DNAI7 CFAP69 WDR49	1.35e-03	898	88	11	GO:0005929
GeneOntologyCellularComponent	ciliary basal body	DLG5 AKAP9 BBS7 RTTN ARMC9	1.41e-03	195	88	5	GO:0036064
GeneOntologyCellularComponent	AP-2 adaptor complex	AP2B1 TBC1D5	1.54e-03	14	88	2	GO:0030122
GeneOntologyCellularComponent	HOPS complex	HOOK3 VPS39	1.54e-03	14	88	2	GO:0030897
GeneOntologyCellularComponent	microtubule organizing center	DLG5 EPS8L2 HOOK3 AKAP9 KIF2B CEP89 BBS7 RTTN TTC12 ARMC9 PCNA	1.62e-03	919	88	11	GO:0005815
GeneOntologyCellularComponent	clathrin coat	AP1B1 AP2B1 TBC1D5	1.70e-03	56	88	3	GO:0030118
GeneOntologyCellularComponent	clathrin coat of endocytic vesicle	AP2B1 TBC1D5	1.78e-03	15	88	2	GO:0030128
Domain	ARM-type_fold	URB1 AP1B1 AP2B1 CIP2A RTTN TTC12 FHOD3 APOB ARMC9 HEATR1 TAF2 ARMC2 CFAP69 FMNL2	4.50e-10	339	86	14	IPR016024
Domain	ARM-like	AP1B1 AP2B1 CIP2A RTTN TTC12 FHOD3 ARMC9 HEATR1 ARMC2 CFAP69	4.55e-07	270	86	10	IPR011989
Domain	-	AP1B1 AP2B1 CIP2A RTTN TTC12 ARMC9 HEATR1 ARMC2 CFAP69	8.38e-07	222	86	9	1.25.10.10
Domain	-	AP1B1 AP2B1	2.10e-05	2	86	2	2.60.40.1150
Domain	Clathrin_b-adaptin_app_Ig-like	AP1B1 AP2B1	2.10e-05	2	86	2	IPR013037
Domain	AP_complex_bsu_1_2_4	AP1B1 AP2B1	6.27e-05	3	86	2	IPR016342
Domain	B2-adapt-app_C	AP1B1 AP2B1	6.27e-05	3	86	2	PF09066
Domain	B-adaptin_app_sub_C	AP1B1 AP2B1	1.25e-04	4	86	2	IPR015151
Domain	B2-adapt-app_C	AP1B1 AP2B1	1.25e-04	4	86	2	SM01020
Domain	AP_beta	AP1B1 AP2B1	2.08e-04	5	86	2	IPR026739
Domain	Beta2_adaptin/TBP_C_dom	AP1B1 AP2B1	3.11e-04	6	86	2	IPR012295
Domain	-	AP1B1 AP2B1	3.11e-04	6	86	2	3.30.310.10
Domain	RA	RASSF6 RASSF8 RAPGEF2	3.86e-04	31	86	3	SM00314
Domain	DAD_dom	FHOD3 FMNL2	5.76e-04	8	86	2	IPR014767
Domain	Coatomer/calthrin_app_sub_C	AP1B1 AP2B1	5.76e-04	8	86	2	IPR009028
Domain	DAD	FHOD3 FMNL2	5.76e-04	8	86	2	PS51231
Domain	RA	RASSF6 RASSF8 RAPGEF2	6.03e-04	36	86	3	PF00788
Domain	RA	RASSF6 RASSF8 RAPGEF2	6.54e-04	37	86	3	PS50200
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP1B1 AP2B1	7.39e-04	9	86	2	IPR008152
Domain	Alpha_adaptinC2	AP1B1 AP2B1	7.39e-04	9	86	2	PF02883
Domain	Alpha_adaptinC2	AP1B1 AP2B1	7.39e-04	9	86	2	SM00809
Domain	ARM	AP1B1 AP2B1 ARMC2	8.23e-04	40	86	3	SM00185
Domain	RA_dom	RASSF6 RASSF8 RAPGEF2	8.23e-04	40	86	3	IPR000159
Domain	RWD	EIF2AK4 WDR59	9.21e-04	10	86	2	PS50908
Domain	Galactose-bd-like	PTPRK CNTNAP2 LAMB1 EPHA8	9.32e-04	94	86	4	IPR008979
Domain	GBD/FH3_dom	FHOD3 FMNL2	1.12e-03	11	86	2	IPR014768
Domain	RWD	EIF2AK4 WDR59	1.12e-03	11	86	2	SM00591
Domain	GBD_FH3	FHOD3 FMNL2	1.12e-03	11	86	2	PS51232
Domain	Armadillo	AP1B1 AP2B1 ARMC2	1.32e-03	47	86	3	IPR000225
Domain	RWD-domain	EIF2AK4 WDR59	1.34e-03	12	86	2	IPR006575
Domain	Coatomer/clathrin_app_Ig-like	AP1B1 AP2B1	1.34e-03	12	86	2	IPR013041
Domain	Clathrin/coatomer_adapt-like_N	AP1B1 AP2B1	2.12e-03	15	86	2	IPR002553
Domain	Adaptin_N	AP1B1 AP2B1	2.12e-03	15	86	2	PF01602
Domain	FH2	FHOD3 FMNL2	2.12e-03	15	86	2	PS51444
Domain	FH2_Formin	FHOD3 FMNL2	2.12e-03	15	86	2	IPR015425
Domain	FH2	FHOD3 FMNL2	2.12e-03	15	86	2	PF02181
Domain	FH2	FHOD3 FMNL2	2.12e-03	15	86	2	SM00498
Domain	-	MORC1 SACS	3.77e-03	20	86	2	3.30.565.10
Domain	HATPase_C	MORC1 SACS	4.16e-03	21	86	2	IPR003594
Domain	AAA+_ATPase	DNAH10 ABCA6 ATAD2B CDC6	4.41e-03	144	86	4	IPR003593
Domain	AAA	DNAH10 ABCA6 ATAD2B CDC6	4.41e-03	144	86	4	SM00382
Pathway	BIOCARTA_EIF2_PATHWAY	EIF2S3 EIF2S3B EIF2AK4	9.51e-06	10	62	3	MM1469
Pathway	REACTOME_LDL_CLEARANCE	AP2B1 APOB SOAT1	6.31e-05	18	62	3	MM15565
Pathway	REACTOME_LDL_CLEARANCE	AP2B1 APOB SOAT1	7.47e-05	19	62	3	M27846
Pubmed	The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.	STX8 PRR5L VPS39 WDR59	1.62e-06	33	90	4	33452816
Pubmed	FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.	CUL1 LIG4 XRCC6	2.72e-06	11	90	3	26774286
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	STX8 DLG5 URB1 AKAP9 SACS CEP89 BBS7 EIF2S3 CIP2A CCDC138 NOL11 LAMB1 HEATR1 XRCC6 SOAT1	6.09e-06	1487	90	15	33957083
Pubmed	Association of XRCC6 C1310G and LIG4 T9I polymorphisms of NHEJ DNA repair pathway with risk of colorectal cancer in the Polish population.	LIG4 XRCC6	6.62e-06	2	90	2	31243170
Pubmed	Analysis of the polymorphisms in non-homologous DNA end joining (NHEJ) gene Ku70 and Ligase IV in sporadic breast cancer in women.	LIG4 XRCC6	6.62e-06	2	90	2	20496270
Pubmed	Can synthetic lethality approach be used with DNA repair genes for primary and secondary MDS?	LIG4 XRCC6	6.62e-06	2	90	2	31667665
Pubmed	Exome sequencing: an efficient diagnostic tool for complex neurodegenerative disorders.	SACS APOB	6.62e-06	2	90	2	23043354
Pubmed	The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer.	PTPRK ZNRF3	6.62e-06	2	90	2	31934854
Pubmed	Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals.	LIG4 XRCC6	6.62e-06	2	90	2	26974709
Pubmed	Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain.	EIF2S3 EIF2S3B	6.62e-06	2	90	2	16325480
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CUL1 STX8 DLG5 AKAP9 GATAD2A AP1B1 AP2B1 AVL9 NOL11 APOB EIF2AK4 FMNL2 XRCC6 PCNA	1.12e-05	1371	90	14	36244648
Pubmed	Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance.	USP36 XRCC6 PCNA	1.58e-05	19	90	3	34188037
Pubmed	A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling.	PTPRK ZNRF3	1.98e-05	3	90	2	34590584
Pubmed	Critical residues in the Ku70 von Willebrand A domain mediate Ku interaction with the LigIV-XRCC4 complex in non-homologous end-joining.	LIG4 XRCC6	1.98e-05	3	90	2	39151475
Pubmed	Influence of functional polymorphisms in DNA repair genes of myelodysplastic syndrome.	LIG4 XRCC6	1.98e-05	3	90	2	27497341
Pubmed	Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.	LIG4 XRCC6	1.98e-05	3	90	2	9823897
Pubmed	The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.	LIG4 XRCC6	1.98e-05	3	90	2	10823907
Pubmed	Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells.	XRCC6 PCNA	1.98e-05	3	90	2	11239001
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CUL1 AKAP9 GATAD2A AP1B1 AP2B1 RASSF6 EIF2S3 CCDC138 NOL11 EIF2S3B EIF2AK4	2.35e-05	910	90	11	36736316
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	GATAD2A VPS39 EIF2S3 CCDC138 LAMB1 EIF2S3B APOB HEATR1 XRCC6 PCNA	2.59e-05	754	90	10	35906200
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	HOOK3 AP1B1 AP2B1 SACS LAMB1 EIF2AK4	3.07e-05	230	90	6	35449600
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	USP36 URB1 AP2B1 EIF2S3 NOL11 HEATR1 XRCC6 PCNA	3.74e-05	483	90	8	36912080
Pubmed	Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: a multiple genotype-phenotype study.	LIG4 XRCC6	3.96e-05	4	90	2	19408343
Pubmed	Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.	LIG4 XRCC6	3.96e-05	4	90	2	20142431
Pubmed	Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.	AP1B1 AP2B1	3.96e-05	4	90	2	17290217
Pubmed	SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation.	CUL1 ZNRF3	3.96e-05	4	90	2	29497989
Pubmed	β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation.	CUL1 DLG5	3.96e-05	4	90	2	31787846
Pubmed	Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.	LIG4 XRCC6	3.96e-05	4	90	2	20133803
Pubmed	Ku recruits the XRCC4-ligase IV complex to DNA ends.	LIG4 XRCC6	3.96e-05	4	90	2	10757784
Pubmed	Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.	EIF2S3 EIF2S3B	3.96e-05	4	90	2	31836389
Pubmed	Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells.	APOB SOAT1	3.96e-05	4	90	2	15308631
Pubmed	Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.	RNASEL DNAH10	3.96e-05	4	90	2	24891332
Pubmed	Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.	ATAD2B PCNA	3.96e-05	4	90	2	24561620
Pubmed	ATM binds to beta-adaptin in cytoplasmic vesicles.	AP1B1 AP2B1	3.96e-05	4	90	2	9707615
Pubmed	Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.	AP1B1 AP2B1	3.96e-05	4	90	2	7534311
Pubmed	The role of DNA breaks in genomic instability and tumorigenesis.	LIG4 XRCC6	6.59e-05	5	90	2	12846809
Pubmed	Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.	LIG4 XRCC6	6.59e-05	5	90	2	11248063
Pubmed	DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.	LIG4 XRCC6	6.59e-05	5	90	2	15520013
Pubmed	Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.	LIG4 XRCC6	6.59e-05	5	90	2	19251090
Pubmed	Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility.	LIG4 XRCC6	6.59e-05	5	90	2	12750264
Pubmed	The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance.	XRCC6 PCNA	6.59e-05	5	90	2	24695737
Pubmed	LDL-cholesterol concentrations: a genome-wide association study.	TDRD15 APOB	6.59e-05	5	90	2	18262040
Pubmed	Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice.	LIG4 XRCC6	6.59e-05	5	90	2	10716994
Pubmed	Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.	CUL1 CDC6	6.59e-05	5	90	2	25557911
Pubmed	Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.	CDC6 PCNA	6.59e-05	5	90	2	9566895
Pubmed	Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.	LIG4 XRCC6	6.59e-05	5	90	2	12547193
Pubmed	Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.	AP1B1 AP2B1	6.59e-05	5	90	2	16723738
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	USP36 CUL1 URB1 TRIM4 DNAH10 EIF2S3 PSMA5 NOL11 APOB HEATR1 XRCC6 SOAT1 PCNA	7.58e-05	1425	90	13	30948266
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CUL1 STX8 URB1 HOOK3 AP2B1 EIF2S3 CIP2A PSMA5 LAMB1 HEATR1 XRCC6 SOAT1 PCNA	8.42e-05	1440	90	13	30833792
Pubmed	DNA-PK suppresses a p53-independent apoptotic response to DNA damage.	LIG4 XRCC6	9.87e-05	6	90	2	19057578
Pubmed	Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12.	LAMB1 APOB	9.87e-05	6	90	2	9598327
Pubmed	Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.	LIG4 XRCC6	9.87e-05	6	90	2	34352203
Pubmed	Clathrin.	AP1B1 AP2B1	9.87e-05	6	90	2	10966473
Pubmed	The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis.	CUL1 CDC6	1.38e-04	7	90	2	37243816
Pubmed	Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17.	CDC6 PCNA	1.38e-04	7	90	2	19150984
Pubmed	A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron.	CUL1 XRCC6	1.38e-04	7	90	2	18784078
Pubmed	Retroviral DNA integration--mechanism and consequences.	LIG4 XRCC6	1.38e-04	7	90	2	16291214
Pubmed	Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.	LAMB1 SOAT1	1.38e-04	7	90	2	8672144
Pubmed	Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.	EIF2S3 EIF2S3B	1.38e-04	7	90	2	15669143
Pubmed	APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage.	CDC6 PCNA	1.38e-04	7	90	2	21768287
Pubmed	Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.	LIG4 XRCC6	1.38e-04	7	90	2	20383123
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AKAP9 AP1B1 CEP89 TBC1D5 CCDC138 RASSF8 RAPGEF2	1.63e-04	446	90	7	24255178
Pubmed	Functional proteomic analysis of human nucleolus.	USP36 URB1 NOL11 HEATR1	1.70e-04	106	90	4	12429849
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	SCUBE1 DNAH10 CNTNAP2 LAMB1 FMNL2	1.73e-04	199	90	5	23382691
Pubmed	XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair.	LIG4 XRCC6	1.84e-04	8	90	2	25941166
Pubmed	Bridging expressed sequence alignments through targeted cDNA sequencing.	SCUBE1 HEATR1	1.84e-04	8	90	2	15028280
Pubmed	Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.	LAMB1 SOAT1	1.84e-04	8	90	2	2993224
Pubmed	A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.	AP1B1 AP2B1	1.84e-04	8	90	2	9811611
Pubmed	Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.	CNTNAP2 APOB	1.84e-04	8	90	2	18496130
Pubmed	Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk.	LIG4 XRCC6	1.84e-04	8	90	2	15958648
Pubmed	The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin.	CUL1 PCNA	1.84e-04	8	90	2	30018425
Pubmed	Essential role of Plzf in maintenance of spermatogonial stem cells.	MORC1 PCNA	1.84e-04	8	90	2	15156143
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	USP36 CUL1 URB1 GATAD2A AP2B1 PSMA5 NOL11 HEATR1 TAF2 WDR59 XRCC6 PCNA	1.90e-04	1353	90	12	29467282
Pubmed	The ORC ubiquitin ligase OBI1 promotes DNA replication origin firing.	CUL1 CDC6 XRCC6	2.06e-04	44	90	3	31160578
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	USP36 DLG5 EPS8L2 GATAD2A AP2B1 HEATR1 PCNA	2.30e-04	472	90	7	38943005
Pubmed	Mig-6 controls EGFR trafficking and suppresses gliomagenesis.	STX8 ZPBP PCNA	2.35e-04	46	90	3	20351267
Pubmed	Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X.	LAMB1 APOB	2.36e-04	9	90	2	8995758
Pubmed	Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.	LIG4 XRCC6	2.36e-04	9	90	2	12091904
Pubmed	Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution.	EIF2S3 EIF2S3B	2.36e-04	9	90	2	9736774
Pubmed	SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation.	CUL1 PCNA	2.36e-04	9	90	2	26666832
Pubmed	Wnt pathway anomalies in developing amygdalae of Turner syndrome-like mice.	EIF2S3 EIF2S3B	2.36e-04	9	90	2	17873295
Pubmed	Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.	AP1B1 AP2B1	2.36e-04	9	90	2	12429846
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CUL1 AP1B1 AP2B1 EIF2S3 CIP2A NOL11 HEATR1 XRCC6	2.54e-04	638	90	8	33239621
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	CUL1 AP1B1 AP2B1 EIF2S3 FMNL2 XRCC6 PCNA	2.74e-04	486	90	7	30940648
Pubmed	FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.	TRIM4 PSMA5 CCDC138 ULK2 SOAT1	2.92e-04	223	90	5	34226595
Pubmed	Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.	AP1B1 AP2B1	2.94e-04	10	90	2	12383505
Pubmed	Genotype-phenotype relationship between DNA repair gene genetic polymorphisms and DNA repair capacity.	LIG4 XRCC6	2.94e-04	10	90	2	18990028
Pubmed	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.	HOOK3 VPS39	2.94e-04	10	90	2	18799622
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	URB1 HOOK3 GATAD2A SACS BBS7 PSMA5 NOL11 HEATR1 XRCC6 PCNA	3.19e-04	1024	90	10	24711643
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	CUL1 MIX23 GATAD2A AP1B1 AP2B1 EIF2S3 TBC1D5 PSMA5 XRCC6	3.51e-04	847	90	9	35235311
Pubmed	Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.	PTPRO LAMB1	3.59e-04	11	90	2	11435469
Pubmed	Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.	PCNA EPHA8	3.59e-04	11	90	2	24550361
Pubmed	The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes.	AKAP9 FHOD3	3.59e-04	11	90	2	36627242
Pubmed	Proliferation inhibition of astrocytes, neurons, and non-glial cells by intracellularly expressed human immunodeficiency virus type 1 (HIV-1) Tat protein.	CDC6 PCNA	3.59e-04	11	90	2	15050687
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PPP1R7 DLG5 HOOK3 CIP2A TBC1D5 CCDC138 TAF2 RASSF8 PCNA	3.70e-04	853	90	9	28718761
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CUL1 DLG5 AKAP9 AP2B1 EIF2S3 PSMA5 LAMB1 RASSF8 XRCC6 PCNA RPAP2	3.76e-04	1247	90	11	27684187
Pubmed	Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.	EIF2S3 EIF2S3B	4.30e-04	12	90	2	23210685
Pubmed	Molecular logic of cellular diversification in the mouse cerebral cortex.	PTPRK TAFA2	4.30e-04	12	90	2	34163074
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AP2B1 PTPRK SACS VPS39 LAMB1 N4BP2L2 DNAI7 RAPGEF2 FMNL2 WDR59 XRCC6	4.83e-04	1285	90	11	35914814
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	CUL1 EIF2S3 PSMA5 LAMB1 EIF2S3B XRCC6 PCNA	5.04e-04	538	90	7	28524877
GeneFamily	Ras association domain family	RASSF6 RASSF8	3.46e-04	10	51	2	1198
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRK PTPRO	1.58e-03	21	51	2	813
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R7 AKAP9 SACS DNAI7	1.68e-03	181	51	4	694
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP	PPP1R7 MIX23 EIF2S3 APOBEC2 CIP2A PSMA5 PCNA	5.55e-06	198	90	7	M5044
Coexpression	GSE14415_INDUCED_VS_NATURAL_TREG_UP	HOOK3 AKAP9 APOBEC2 CARD6 MPPE1 ULK2	1.28e-05	149	90	6	M2968
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 DNAH10 DNAI7 ARMC2 CFAP69 WDR49 LRRC9	1.52e-07	197	90	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HCAR3 DLG5 RASSF6 FHOD3 FGF11 WDR49	3.17e-06	199	90	6	f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MORC1 PTPRO CNTNAP2 FGF11 TAFA2	6.73e-06	130	90	5	8bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RASSF6 FGF11 NXPH2 INPP4B TAFA2	2.07e-05	164	90	5	f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	USP36 AKAP9 N4BP2L2 APOB INPP4B	2.53e-05	171	90	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	AT1-AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	LIG4 DLG5 RASSF6 CNTNAP2 FGF11	2.53e-05	171	90	5	0b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORC1 CCNG2 LIG4 XRCC6 SOAT1	3.69e-05	185	90	5	dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRK RASSF6 LAMB1 FHOD3 FMNL2	3.78e-05	186	90	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	DNAH10 FHOD3 DNAI7 CFAP69 WDR49	3.98e-05	188	90	5	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MORC1 CCNG2 LIG4 XRCC6 SOAT1	3.98e-05	188	90	5	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 DNAI7 ARMC2 CFAP69 WDR49	4.51e-05	193	90	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH10 DNAI7 ARMC2 CFAP69 WDR49	4.51e-05	193	90	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CIP2A RTTN CDC6 NXPH2 PCNA	4.74e-05	195	90	5	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH10 DNAI7 ARMC2 CFAP69 WDR49	4.74e-05	195	90	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 DNAI7 ARMC2 CFAP69 WDR49	4.97e-05	197	90	5	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD8+_Tcm\|URO / Disease, condition lineage and cell class	EPS8L2 SACS ZNF781 FXYD7 INPP4B	5.22e-05	199	90	5	eb085f9f2c837494548c26bb61e8b74516539e23
ToppCell	Transverse-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	USP36 EIF2S3 TTC12 FXYD7 INPP4B	5.34e-05	200	90	5	d89d3c16406d77cb08e1aa00d7df6887a692c337
Drug	LY294002; Up 200; 10uM; MCF7; HG-U133A	CCNG2 AKAP9 AP1B1 N4BP2L2 RAPGEF2 ALDH6A1 MPPE1	9.76e-06	190	89	7	328_UP
Drug	LY294002; Up 200; 10uM; SKMEL5; HG-U133A	CCNG2 PPP1R7 GPR4 RNASEL AVL9 MPPE1 SOAT1	1.08e-05	193	89	7	501_UP
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	CCNG2 LIG4 URB1 TBC1D5 MPPE1 ULK2 WDR59	1.12e-05	194	89	7	7538_DN
Drug	Methylatropine nitrate [52-88-0]; Down 200; 11uM; PC3; HT_HG-U133A	CCNG2 AVL9 VPS39 TTC12 TNFAIP8 RASSF8 MPPE1	1.23e-05	197	89	7	7253_DN
Disease	MEHMO syndrome (implicated_via_orthology)	EIF2S3 EIF2S3B	8.40e-06	2	86	2	DOID:0060801 (implicated_via_orthology)
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 RASSF6 APOB	8.50e-06	14	86	3	EFO_0004611, EFO_0008589
Disease	low density lipoprotein cholesterol measurement, physical activity	TDRD15 ABCA6 CNTNAP2 APOB	4.22e-05	66	86	4	EFO_0003940, EFO_0004611
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 ABCA6 RASSF6 TBC1D5 APOB	5.16e-05	137	86	5	EFO_0004611, EFO_0008591
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	TDRD15 GATAD2A DNAH10 ABCA6 TBC1D5 APOB	5.20e-05	225	86	6	EFO_0008317, EFO_0010351
Disease	hypopituitarism (implicated_via_orthology)	EIF2S3 EIF2S3B	1.25e-04	6	86	2	DOID:9406 (implicated_via_orthology)
Disease	obsolete_red blood cell distribution width	USP36 HCAR3 GATAD2A AP2B1 ABCA6 ZNRF3 AVL9 TBC1D5 ATAD2B APOB EIF2AK4 ALDH6A1 INPP4B	1.38e-04	1347	86	13	EFO_0005192
Disease	free cholesterol to total lipids in large VLDL percentage	TDRD15 ABCA6 APOB	1.73e-04	37	86	3	EFO_0022281
Disease	LDL cholesterol change measurement	APOB PKD1L3	1.75e-04	7	86	2	EFO_0007804
Disease	lipid measurement, intermediate density lipoprotein measurement	TDRD15 ABCA6 TBC1D5 APOB	1.82e-04	96	86	4	EFO_0004529, EFO_0008595
Disease	myositis	PRR5L AP1B1 PHTF1	2.02e-04	39	86	3	EFO_0000783
Disease	total cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 ABCA6 TBC1D5 APOB	2.05e-04	99	86	4	EFO_0004574, EFO_0008595
Disease	phospholipid measurement, intermediate density lipoprotein measurement	TDRD15 ABCA6 TBC1D5 APOB	2.05e-04	99	86	4	EFO_0004639, EFO_0008595
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TDRD15 HCAR3 GATAD2A DNAH10 ABCA6 APOB	2.12e-04	291	86	6	EFO_0008317, EFO_0020946
Disease	cholesterol in very small VLDL measurement	TDRD15 ABCA6 APOB	2.18e-04	40	86	3	EFO_0022231
Disease	free cholesterol in medium LDL measurement	TDRD15 ABCA6 APOB	2.18e-04	40	86	3	EFO_0022268
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 APOB	2.32e-04	8	86	2	EFO_0008589, EFO_0008595
Disease	response to antihypertensive drug	RNASEL RAPGEF2 FMNL2	2.35e-04	41	86	3	EFO_0005405
Disease	free cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 ABCA6 TBC1D5 APOB	2.48e-04	104	86	4	EFO_0008591, EFO_0008595
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	DNAH10 ZNRF3 LAMB1 TNFAIP8	2.57e-04	105	86	4	EFO_0007788, EFO_0008007, EFO_0008343
Disease	liver fat measurement	GATAD2A RASSF6 CNTNAP2	2.71e-04	43	86	3	EFO_0010821
Disease	concentration of large LDL particles measurement	TDRD15 ABCA6 APOB	2.90e-04	44	86	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	TDRD15 ABCA6 APOB	2.90e-04	44	86	3	EFO_0022225
Disease	leukodystrophy (implicated_via_orthology)	EIF2S3 EIF2S3B	2.98e-04	9	86	2	DOID:10579 (implicated_via_orthology)
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	TDRD15 HCAR3 DNAH10 ABCA6 APOB	3.04e-04	200	86	5	EFO_0004611, EFO_0020945
Disease	cholesterol to total lipids in large VLDL percentage	TDRD15 ABCA6 APOB	3.10e-04	45	86	3	EFO_0022236
Disease	Intellectual Disability	AP1B1 SACS BBS7 EIF2S3 RTTN ARMC9 TAF2	3.35e-04	447	86	7	C3714756
Disease	free cholesterol in very small VLDL measurement	TDRD15 ABCA6 APOB	3.53e-04	47	86	3	EFO_0022275
Disease	mean corpuscular hemoglobin concentration	CUL1 HCAR3 PRR5L GATAD2A ABCA6 ZNRF3 BBS7 ATAD2B RTTN N4BP2L2 EIF2AK4	3.62e-04	1105	86	11	EFO_0004528
Disease	level of Triacylglycerol (51:3) in blood serum	GATAD2A APOB	3.72e-04	10	86	2	OBA_2045163
Disease	phospholipids in medium LDL measurement	TDRD15 ABCA6 APOB	4.00e-04	49	86	3	EFO_0022183
Disease	cholesteryl esters to total lipids in small VLDL percentage	TDRD15 ABCA6 APOB	4.00e-04	49	86	3	EFO_0022256
Disease	free cholesterol in LDL measurement	TDRD15 ABCA6 APOB	4.24e-04	50	86	3	EFO_0022266
Disease	free cholesterol in large LDL measurement	TDRD15 ABCA6 APOB	4.50e-04	51	86	3	EFO_0022176
Disease	phospholipids in IDL measurement	TDRD15 ABCA6 APOB	4.76e-04	52	86	3	EFO_0022164
Disease	total lipids in LDL measurement	TDRD15 ABCA6 APOB	4.76e-04	52	86	3	EFO_0022308
Disease	triglycerides to total lipids in very large VLDL percentage	TDRD15 ABCA6 APOB	5.04e-04	53	86	3	EFO_0022340
Disease	phospholipids in large LDL measurement	TDRD15 ABCA6 APOB	5.04e-04	53	86	3	EFO_0022174
Disease	free cholesterol in small LDL measurement	TDRD15 ABCA6 APOB	5.04e-04	53	86	3	EFO_0022271
Disease	cholesteryl esters to total lipids in very large VLDL percentage	TDRD15 ABCA6 APOB	5.04e-04	53	86	3	EFO_0022258
Disease	cholesterol to total lipids in very large VLDL percentage	TDRD15 ABCA6 APOB	5.33e-04	54	86	3	EFO_0022244
Disease	triglycerides in medium VLDL measurement	TDRD15 DNAH10 APOB	5.62e-04	55	86	3	EFO_0022155
Disease	free cholesterol to total lipids in large HDL percentage	TDRD15 ABCA6 APOB	5.93e-04	56	86	3	EFO_0022279
Disease	cholesteryl esters to total lipids in large VLDL percentage	TDRD15 ABCA6 APOB	5.93e-04	56	86	3	EFO_0022250
Disease	total lipids in large LDL	TDRD15 ABCA6 APOB	6.24e-04	57	86	3	EFO_0022163
Disease	cholesterol in large LDL measurement	TDRD15 ABCA6 APOB	6.24e-04	57	86	3	EFO_0021901
Disease	Amino Acid Metabolism, Inherited Disorders	EIF2AK4 ALDH6A1	6.41e-04	13	86	2	C0750905
Disease	Amino Acid Metabolism, Inborn Errors	EIF2AK4 ALDH6A1	6.41e-04	13	86	2	C0002514
Disease	cholesterol in IDL measurement	TDRD15 ABCA6 APOB	6.57e-04	58	86	3	EFO_0021899
Disease	phospholipids in LDL measurement	TDRD15 ABCA6 APOB	6.57e-04	58	86	3	EFO_0022294
Disease	phospholipids in small LDL measurement	TDRD15 ABCA6 APOB	6.91e-04	59	86	3	EFO_0022297
Disease	free cholesterol to total lipids in very large VLDL percentage	TDRD15 ABCA6 APOB	6.91e-04	59	86	3	EFO_0022289
Disease	total lipids in IDL	TDRD15 ABCA6 APOB	7.25e-04	60	86	3	EFO_0022161
Disease	triglycerides in small VLDL measurement	TDRD15 DNAH10 APOB	7.61e-04	61	86	3	EFO_0022145
Disease	free cholesterol in IDL measurement	TDRD15 ABCA6 APOB	7.61e-04	61	86	3	EFO_0022181
Disease	free cholesterol in very large VLDL measurement	TDRD15 DNAH10 APOB	7.61e-04	61	86	3	EFO_0022274
Disease	phospholipids in large VLDL measurement	TDRD15 DNAH10 APOB	7.98e-04	62	86	3	EFO_0022169
Disease	phospholipids in very large VLDL measurement	TDRD15 DNAH10 APOB	7.98e-04	62	86	3	EFO_0022299
Disease	low density lipoprotein triglyceride measurement	TDRD15 APOB	8.60e-04	15	86	2	EFO_0009946
Disease	response to statin, LDL cholesterol change measurement	TDRD15 APOB	8.60e-04	15	86	2	EFO_0007804, GO_0036273
Disease	cholesterol in large VLDL measurement	TDRD15 DNAH10 APOB	9.16e-04	65	86	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	TDRD15 DNAH10 APOB	9.16e-04	65	86	3	EFO_0022230
Disease	response to methotrexate	PRR5L INPP4B	9.81e-04	16	86	2	GO_0031427
Disease	total lipids in small VLDL	TDRD15 DNAH10 APOB	1.00e-03	67	86	3	EFO_0022148
Disease	total lipids in large VLDL	TDRD15 DNAH10 APOB	1.00e-03	67	86	3	EFO_0022175
Disease	common carotid intimal medial thickness	TDRD15 CNTNAP2 APOB	1.00e-03	67	86	3	EFO_0004860
Disease	free cholesterol in large VLDL measurement	TDRD15 DNAH10 APOB	1.04e-03	68	86	3	EFO_0022265
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	TDRD15 HCAR3 DNAH10 ABCA6 APOB	1.07e-03	264	86	5	EFO_0008317, EFO_0020944
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 APOB	1.11e-03	17	86	2	EFO_0022232
Disease	Tourette syndrome, schizophrenia	DNAH10 TBC1D5	1.25e-03	18	86	2	EFO_0004895, MONDO_0005090
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 APOB	1.25e-03	18	86	2	EFO_0008317, EFO_0008589
Disease	Chronic myeloproliferative disorder	LIG4 CDC6	1.39e-03	19	86	2	C1292778
Disease	age of onset of asthma	RASSF6 TLR6 RPAP2	1.61e-03	79	86	3	OBA_2001001
Disease	Seckel syndrome	LIG4 CDC6	1.87e-03	22	86	2	C0265202
Disease	proprotein convertase subtilisin/kexin type 9 measurement	TDRD15 APOB	1.87e-03	22	86	2	EFO_0009312
Disease	lipoprotein measurement, phospholipid measurement	TDRD15 ABCA6 APOB	1.99e-03	85	86	3	EFO_0004639, EFO_0004732
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	TDRD15 HCAR3 ABCA6 APOB PKD1L3	2.07e-03	307	86	5	EFO_0004612, EFO_0020946
Disease	intermediate density lipoprotein measurement	TDRD15 ABCA6 APOB	2.12e-03	87	86	3	EFO_0008595
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	TDRD15 HCAR3 DNAH10 ABCA6 APOB	2.31e-03	315	86	5	EFO_0004612, EFO_0008591
Disease	lipid measurement, lipoprotein measurement	TDRD15 ABCA6 APOB	2.34e-03	90	86	3	EFO_0004529, EFO_0004732
Disease	sleep duration, low density lipoprotein cholesterol measurement	TDRD15 APOB PKD1L3	2.41e-03	91	86	3	EFO_0004611, EFO_0005271
Disease	level of Sterol ester (27:1/18:2) in blood serum	TDRD15 APOB	2.61e-03	26	86	2	OBA_2045194
Disease	cholesteryl ester measurement, intermediate density lipoprotein measurement	TDRD15 ABCA6 APOB	2.65e-03	94	86	3	EFO_0008595, EFO_0010351
Disease	alkaline phosphatase measurement	TDRD15 DLG5 ABCA6 ZNRF3 N4BP2L2 APOB PKD1L3 PHTF1 EPHA8	2.80e-03	1015	86	9	EFO_0004533
Disease	cholesterol to total lipids in medium LDL percentage	TDRD15 APOB	2.81e-03	27	86	2	EFO_0022238

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLLLAKKVQLIDALK	BBS7	616	Q8IWZ6
KANNRLLKILLEVVK	AKAP9	1726	Q99996
QLTLLTAIVKLFLKK	AP2B1	481	P63010
LLKKLGIKLQVLINL	EIF2AK4	1301	Q9P2K8
LSLKLAKIILALKVS	ARMC2	331	Q8NEN0
QDKKLYIAELLLKLL	ARMC2	671	Q8NEN0
LKLKRQTKVLLTLLL	ABCA6	846	Q8N139
VELLEILLLVKKHSK	CCNG2	221	Q16589
QLQLLTAIVKLFLKK	AP1B1	481	Q10567
IKTLSKTKNLRLLIL	APOBEC2	136	Q9Y235
IKTVKLNLLITGKIV	NXPH2	121	O95156
LKKLIRLQTEKLQSI	RASSF8	166	Q8NHQ8
AIILKCLQNKLVIKT	RASSF6	351	Q6ZTQ3
SKIENLEKLIKLKVL	LRRC9	111	Q6ZRR7
KLKNLRIKLALLLQK	MORC1	916	Q86VD1
IALKKKDVQLLQLCL	NOL11	476	Q9H8H0
EAKLVLLKKLRQSQI	GATAD2A	156	Q86YP4
LKLLKELTSKKSLQV	MGAT4A	91	Q9UM21
LIKENLKEIAKLITL	ALDH6A1	111	Q02252
LKKLLDLLVDKSNNL	ATAD2B	1401	Q9ULI0
KLKLIKFLALISKAS	ARMC9	176	Q7Z3E5
KVGELLKSKEQLLVL	INPP4B	151	O15327
LKRKSSLLLKLIAVV	MPPE1	16	Q53F39
LVQGSILKKVLEALK	PCNA	6	P12004
AKAELLLKLLLAKER	DLG5	51	Q8TDM6
NLLKITNLRIKFVKL	LAMB1	226	P07942
LKEAIKSSLIILKQV	PSMA5	191	P28066
LKISNLKKILKGILD	HOOK3	71	Q86VS8
IKLAINLLAKLQKHI	EPS8L2	321	Q9H6S3
KIKRLALSLIAIVLV	GPR4	221	P46093
LLLVTLIILRKKHLQ	PTPRO	836	Q16827
VLLKVKLGDLLLLAQ	PRR5L	166	Q6MZQ0
KSLCQKQLLILLSKV	FGF11	36	Q92914
KIVSLIKNLLVALKD	APOB	4406	P04114
FIFLKILKLLISKLK	GLP2R	356	O95838
TDLLKKSRKLLILVQ	CARD6	51	Q9BX69
ILEKLSIILQKLSKI	CCDC138	596	Q96M89
AKRKDLIKKSLLQLI	LIG4	161	P49917
KLTVLQAQKKSLLLE	CEP89	541	Q96ST8
LAQVLQILLKSKLLV	CUL1	636	Q13616
VLILFKLILLEKKVL	AVL9	191	Q8NBF6
ITGLVVLLLLLICKK	EPHA8	551	P29322
SKFRLVVKTALKLLL	FHOD3	201	Q2V2M9
KVVLNLIEKLKFILL	DNAI7	136	Q6TDU7
LIRQLKIKEVTLGKL	CDC6	471	Q99741
QKLKKILEIILALGN	FMNL2	816	Q96PY5
ITLELKKAKLVLSLN	CNTNAP2	236	Q9UHC6
AIRVFSLLQKKIKKL	HEATR1	726	Q9H583
RVTLILELLQHKKKL	HEATR1	1206	Q9H583
KLKHILILQNKIDLV	EIF2S3B	181	Q2VIR3
LKKLLFNVIVILCKD	CFAP69	366	A5D8W1
KKIYEVLTKLILKNL	DNAH10	866	Q8IVF4
VLKKVKTLCLRQNLI	PPP1R7	96	Q15435
ILKDKKLIKALFDVL	SCUBE1	936	Q8IWY4
QDVLLKKAKTLLLVL	SACS	1121	Q9NZJ4
LLAIKLSVLKAIKVS	FTH1P19	186	P0C7X4
ALTEIQKKLKLLLAD	KIF2B	651	Q8N4N8
LLLVVILIVKKSKLA	PTPRK	766	Q15262
SLRNKEVKVALKKLL	OR13F1	291	Q8NGS4
KLLIDIIHFLNKLIK	RTTN	1141	Q86VV8
LQKATKGKLLIIIFI	TAFA2	6	Q8N3H0
RIDIKQLIAKKIKLT	SOAT1	41	P35610
LSLGLQEKILKKLKT	TMCO2	121	Q7Z6W1
FKKLVLNKAILLQVI	TDRD15	616	B5MCY1
LSKNKKILSDLIVLI	TDRD15	1546	B5MCY1
ELGLVLNLKEKKAVL	TAF2	991	Q6P1X5
LFLLGILIVISKKVK	FXYD7	36	P58549
VGLTVHLLKKKLLIQ	HCAR3	156	P49019
KKLFKLTGDILVQIL	PKD1L3	1276	Q7Z443
ALLLAVELKLKKIAE	RNASEL	276	Q05823
IIKNLIKTVIKLAIL	TNFAIP8	71	O95379
LQLKSLTKLLIMKIL	URB1	651	O60287
ADVILKTLDLINKLK	CIP2A	476	Q8TCG1
NKLKKILDKTRISIL	RAPGEF2	531	Q9Y4G8
LSRLKLKLNKDIVIS	XRCC6	256	P12956
LTLLKQLRKEQTKLK	MIX23	96	Q4VC31
LVNNVLKLSTKLLKE	PHTF1	701	Q9UMS5
VGKRNLLKVLKETLI	RPAP2	361	Q8IXW5
AVDISQILILKKKIL	WDR49	236	Q8IV35
ALLQNLKEKIALLKD	STX8	46	Q9UNK0
LVKLETLILQKNGLK	TLR6	376	Q9Y2C9
EKKLLQILSKLLLDL	ZPBP	191	Q9BS86
LLKILKDTALQKVKR	WDR59	461	Q6PJI9
LSKSQILLGKEIKIL	ULK2	46	Q8IYT8
ILLGKEIKILKELQH	ULK2	51	Q8IYT8
LVCLILLVKIKLKQR	ZNRF3	231	Q9ULT6
SLLKTDLLQVLLKLA	TTC12	641	Q9H892
LVSLAGLKQIKDILK	TBC1D5	636	Q92609
TLKLNQTIASLKKLI	TRIM4	236	Q9C037
VKRLLGKVHILLNIK	ZNF781	206	Q8N8C0
KLLASSAKKVLLQKI	USP36	26	Q9P275
KSKKKLLQIIDTTLL	VPS39	451	Q96JC1
KLKHILILQNKIDLV	EIF2S3	181	P41091
KLNKLQKLLILLRGL	N4BP2L2	396	Q92802